What is it about?
The MSCs are guided by inflammatory mediators and specific interactions with immune cells occur, especially between MSCs and the cells of the innate immune system. At the present many of these interactions remain to be determined.
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Why is it important?
This review summarizes the current knowledge in relation to the susceptibility of MSCs to NK cell mediated lysis as well as the immunomodulatory activity of MSCs and its control over NK cell function. Here we hypothesize that the inflammatory context will regulate the outcome of NK-MSC interactions.
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This page is a summary of: NK and MSCs Crosstalk: The Sense of Immunomodulation and Their Sensitivity, Stem Cell Reviews and Reports, February 2013, Springer Science + Business Media,
DOI: 10.1007/s12015-013-9430-y.
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