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  1. Comparative evaluation of three culture media for domestic cat in vitro embryo production and their effects on blastocyst development

    Article • Theriogenology, January 2026, Elsevier

    PhD Alfonso Gutierrez-Adan

  2. Dynamic Remodeling of the Zona Pellucida: Implications for Oocyte Competence and Assisted Reproduction

    Article • International Journal of Molecular Sciences, November 2025, MDPI AG

    PhD Alfonso Gutierrez-Adan

  3. Follicular fluid secretome enhances the meiotic competence of in vitro matured equine oocytes, but not the developmental competence of zygotes after intracytoplasmic sperm injection (ICSI)

    Article • Animal Reproduction Science, August 2025, Elsevier

    PhD Alfonso Gutierrez-Adan

  4. Oviductin sets the species-specificity of the mammalian zona pellucida

    Article • eLife, June 2025, eLife

    PhD Alfonso Gutierrez-Adan

  5. Oviductin sets the species-specificity of the mammalian zona pellucida

    Article • eLife, June 2025, eLife

    PhD Alfonso Gutierrez-Adan

  6. Integrating immune library probing with structure-based computational design to develop potent neutralizing nanobodies against emerging SARS-CoV-2 variants

    Article • mAbs, May 2025, Taylor & Francis

    PhD Alfonso Gutierrez-Adan

  7. Synthetic heparan sulfate mimics based on chitosan derivatives show broad-spectrum antiviral activity

    Article • Communications Biology, March 2025, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  8. Fermented Lignan-Enriched Soy Beverage Ameliorates the Metabolic Effects of a High-Fat Diet on Female Mice

    Article • Journal of Agricultural and Food Chemistry, February 2025, American Chemical Society (ACS)

    PhD Alfonso Gutierrez-Adan

  9. Effect of long-term moderate red wine consumption in CD1 female mice

    Article • Food & Function, January 2025, Royal Society of Chemistry

    PhD Alfonso Gutierrez-Adan

  10. A new hormonal protocol supports early development of in vitro‐produced embryos after transfer to anoestrus mares

    Article • Reproduction in Domestic Animals, October 2024, Wiley

    PhD Alfonso Gutierrez-Adan

  11. RNA Sequencing of Sperm from Healthy Cattle and Horses Reveals the Presence of a Large Bacterial Population

    Article • Current Issues in Molecular Biology, September 2024, MDPI AG

    PhD Alfonso Gutierrez-Adan

  12. Synthetic heparan sulfate mimics based on chitosan derivatives show broad-spectrum antiviral activity

    Article • July 2024, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  13. Oviductin sets the species-specificity of the mammalian zona pellucida

    Article • July 2024, Cold Spring Harbor Laboratory Press

    PhD Alfonso Gutierrez-Adan

  14. Preovulatory follicular fluid secretome added to in vitro maturation medium influences the metabolism of equine cumulus-oocyte complexes

    Article • BMC Veterinary Research, June 2024, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  15. Susceptibility and transmissibility of SARS-CoV-2 variants in transgenic mice expressing the cat angiotensin-converting enzyme 2 (ACE-2) receptor

    Article • One Health, June 2024, Elsevier

    PhD Alfonso Gutierrez-Adan

  16. Characterization of preovulatory follicular fluid secretome and its effects on equine oocytes during in vitro maturation

    Article • Research in Veterinary Science, May 2024, Elsevier

    PhD Alfonso Gutierrez-Adan, Dr Javier G Casado

  17. MicroRNA-148b secreted by bovine oviductal extracellular vesicles enhance embryo quality through BPM/TGF-beta pathway

    Article • Biological Research, March 2024, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  18. AG5 is a potent non-steroidal anti-inflammatory and immune regulator that preserves innate immunity

    Article • Biomedicine & Pharmacotherapy, December 2023, Elsevier

    PhD Alfonso Gutierrez-Adan

  19. Male fertility - a lesson from the cattle world

    Article • Proceedings of the National Academy of Sciences, October 2023, Proceedings of the National Academy of Sciences

    Pat Lonergan, PhD Alfonso Gutierrez-Adan

  20. Effect of fermented soy beverage in aged female mice model

    Article • Food Research International, July 2023, Elsevier

    PhD Alfonso Gutierrez-Adan

  21. Loss of the importin Kpna2 causes infertility in male mice by disrupting the translocation of testis-specific transcription factors

    Article • iScience, July 2023, Elsevier

    PhD Alfonso Gutierrez-Adan

  22. 059 Effect of bta-miR-483-3p of extracellular vesicles from the oviductal fluid of pregnant cows on in vitro early embryo development

    Article • Animal - science proceedings, May 2023, Elsevier

    PhD Alfonso Gutierrez-Adan

  23. 060 bta-miR-133b secreted by extracellular vesicles from the oviduct of pregnant cows could modulate signalling pathways during early embryo development

    Article • Animal - science proceedings, May 2023, Elsevier

    PhD Alfonso Gutierrez-Adan

  24. An ancient testis-specific IQ motif-containing H gene regulates specific transcript isoform expression during spermatogenesis

    Article • Development, April 2023, The Company of Biologists

    PhD Alfonso Gutierrez-Adan

  25. Non-coding RNAs derived from the foot-and-mouth disease virus genome trigger broad antiviral activity against coronaviruses

    Article • Frontiers in Immunology, March 2023, Frontiers

    PhD Alfonso Gutierrez-Adan

  26. Acquisition of fertilization competence in guinea pig spermatozoa under different capacitation protocols

    Article • Theriogenology, March 2023, Elsevier

    PhD Alfonso Gutierrez-Adan

  27. Identification and differential expression of long non-coding RNAs and their association with XIST gene during early embryonic developmental stages of Bos taurus

    Article • International Journal of Biological Macromolecules, February 2023, Elsevier

    PhD Alfonso Gutierrez-Adan

  28. Bull spermatozoa selected by thermotaxis exhibit high DNA integrity, specific head morphometry, and improve ICSI outcome

    Article • Journal of Animal Science and Biotechnology, January 2023, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  29. Extracellular vesicles from oviductal and uterine fluids supplementation in sequential in vitro culture improves bovine embryo quality

    Article • Journal of Animal Science and Biotechnology, October 2022, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  30. Concurrent Zrsr2 mutation and Tet2 loss promote myelodysplastic neoplasm in mice

    Article • Leukemia, August 2022, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  31. Bull spermatozoa selected by thermotaxis exhibit high DNA integrity, specific head morphometry, and improve ICSI outcome

    Article • July 2022, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  32. d ‐Pinitol promotes tau dephosphorylation through a cyclin‐dependent kinase 5 regulation mechanism: A new potential approach for tauopathies?

    Article • Bone Marrow Transplantation, July 2022, Wiley

    PhD Alfonso Gutierrez-Adan

  33. Extracellular vesicles from oviductal and uterine fluids supplementation in sequential in vitro culture improves bovine embryo quality

    Article • April 2022, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  34. Transit along the vas deferens results in a high percentage of filiform spermatozoa with compacted chromatin in the rooster (

    Article • Reproduction Fertility and Development, April 2022, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  35. The Role of Aquaporin 7 in the Movement of Water and Cryoprotectants in Bovine In Vitro Matured Oocytes

    Article • Animals, February 2022, MDPI AG

    PhD Alfonso Gutierrez-Adan

  36. Zrsr2 and functional U12-dependent spliceosome are necessary for follicular development

    Article • iScience, February 2022, Elsevier

    PhD Alfonso Gutierrez-Adan

  37. The impact of CD160 deficiency on alloreactive CD8 T cell responses and allograft rejection

    Article • Translational Research, January 2022, Elsevier

    PhD Alfonso Gutierrez-Adan, DVM, PhD Maria-Luisa del Rio-Gonzalez

  38. 90 Guinea pig sperm is capable of fertilising bovine zona-intact oocytes

    Article • Reproduction Fertility and Development, December 2021, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  39. 91 Fertilising capacity of guinea pig spermatozoa by heterologous fertilisation with zona-intact murine oocytes

    Article • Reproduction Fertility and Development, December 2021, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  40. Characterization and profiling analysis of bovine oviduct and uterine extracellular vesicles and their miRNA cargo through the estrous cycle

    Article • The FASEB Journal, November 2021, Wiley

    PhD Alfonso Gutierrez-Adan

  41. Nobiletin-induced partial abrogation of deleterious effects of AKT inhibition on preimplantation bovine embryo development in vitro†

    Article • Biology of Reproduction, October 2021, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  42. A drastic shift in the energetic landscape of toothed whale sperm cells

    Article • Current Biology, August 2021, Elsevier

    PhD Alfonso Gutierrez-Adan

  43. Activation of PI3K/Akt Signaling Pathway in Rat Hypothalamus Induced by an Acute Oral Administration of D-Pinitol

    Article • Nutrients, June 2021, MDPI AG

    PhD Alfonso Gutierrez-Adan

  44. Aberrant Alternative Splicing in U2af1/Tet2 Double Mutant Mice Contributes to Major Hematological Phenotypes

    Article • International Journal of Molecular Sciences, June 2021, MDPI AG

    PhD Alfonso Gutierrez-Adan

  45. Nobiletin enhances the development and quality of bovine embryos in vitro during two key periods of embryonic genome activation

    Article • Scientific Reports, June 2021, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  46. Sperm Metabolomics through Nuclear Magnetic Resonance Spectroscopy

    Article • Animals, June 2021, MDPI AG

    PhD Alfonso Gutierrez-Adan

  47. MicroRNAs in amniotic fluid and maternal blood plasma associated with sex determination and early gonad differentiation in cattle

    Article • Biology of Reproduction, April 2021, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  48. Postnatal Catch-Up Growth Programs Telomere Dynamics and Glucose Intolerance in Low Birth Weight Mice

    Article • International Journal of Molecular Sciences, April 2021, MDPI AG

    PhD Alfonso Gutierrez-Adan

  49. Impact of Overuse and Sexually Transmitted Infections on Seminal Parameters of Extensively Managed Bulls

    Article • Animals, March 2021, MDPI AG

    PhD Alfonso Gutierrez-Adan

  50. Sperm selection by rheotaxis improves sperm quality and early embryo development

    Article • Reproduction, March 2021, Bioscientifica

    Prof. Andreas Martin Grabrucker, PhD Alfonso Gutierrez-Adan

  51. Effect of an altered hormonal environment by blood plasma collected after adrenocorticotropic administration on embryo development and gene expression in porcine embryos

    Article • Theriogenology, March 2021, Elsevier

    PhD Alfonso Gutierrez-Adan

  52. A drastic shift in the energetic landscape of toothed whale sperm cells

    Article • March 2021, Cold Spring Harbor Laboratory Press

    PhD Alfonso Gutierrez-Adan

  53. Genome-wide DNA methylation dynamics during epigenetic reprogramming in the porcine germline

    Article • Clinical Epigenetics, February 2021, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  54. ZP4 Is Present in Murine Zona Pellucida and Is Not Responsible for the Specific Gamete Interaction

    Article • Frontiers in Cell and Developmental Biology, January 2021, Frontiers

    PhD Alfonso Gutierrez-Adan

  55. Effects of <i>Zrsr2</i> Mutations in Mice Oogenesis, Peripheral Blood Cells and Muscle Strength

    Article • SSRN Electronic Journal, January 2021, Elsevier

    PhD Alfonso Gutierrez-Adan

  56. Isolation, Characterization, and MicroRNA Analysis of Extracellular Vesicles from Bovine Oviduct and Uterine Fluids

    Article • January 2021, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  57. Role of Alternative Splicing in Sex Determination in Vertebrates

    Article • Sexual Development, January 2021, Karger Publishers

    PhD Alfonso Gutierrez-Adan

  58. Senescence and Apoptosis During in vitro Embryo Development in a Bovine Model

    Article • Frontiers in Cell and Developmental Biology, December 2020, Frontiers

    PhD Alfonso Gutierrez-Adan

  59. Inhibiting diacylglycerol acyltransferase-1 reduces lipid biosynthesis in bovine blastocysts produced in vitro

    Article • Theriogenology, December 2020, Elsevier

    PhD Alfonso Gutierrez-Adan

  60. Effect of supplementation of valine to chicken extender on sperm cryoresistance and post-thaw fertilization capacity

    Article • Poultry Science, December 2020, Elsevier

    PhD Alfonso Gutierrez-Adan

  61. A high glucose concentration during early stages of in vitro equine embryo development alters expression of genes involved in glucose metabolism

    Article • Equine Veterinary Journal, October 2020, Wiley

    PhD Alfonso Gutierrez-Adan

  62. D-Chiro-Inositol Treatment Affects Oocyte and Embryo Quality and Improves Glucose Intolerance in Both Aged Mice and Mouse Models of Polycystic Ovarian Syndrome

    Article • International Journal of Molecular Sciences, August 2020, MDPI AG

    PhD Alfonso Gutierrez-Adan

  63. The Presence of D-Penicillamine during the In Vitro Capacitation of Stallion Spermatozoa Prolongs Hyperactive-Like Motility and Allows for Sperm Selection by Thermotaxis

    Article • Animals, August 2020, MDPI AG

    PhD Alfonso Gutierrez-Adan

  64. Antioxidant Nobiletin Enhances Oocyte Maturation and Subsequent Embryo Development and Quality

    Article • International Journal of Molecular Sciences, July 2020, MDPI AG

    PhD Alfonso Gutierrez-Adan

  65. D-Pinitol from Ceratonia siliqua Is an Orally Active Natural Inositol That Reduces Pancreas Insulin Secretion and Increases Circulating Ghrelin Levels in Wistar Rats

    Article • Nutrients, July 2020, MDPI AG

    PhD Alfonso Gutierrez-Adan

  66. Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion

    Article • International Journal of Molecular Sciences, June 2020, MDPI AG

    PhD Alfonso Gutierrez-Adan

  67. TMEM95 is a sperm membrane protein essential for mammalian fertilization

    Article • eLife, June 2020, eLife

    PhD Alfonso Gutierrez-Adan

  68. Study of the Metabolomics of Equine Preovulatory Follicular Fluid: A Way to Improve Current In Vitro Maturation Media

    Article • Animals, May 2020, MDPI AG

    PhD Alfonso Gutierrez-Adan

  69. Oxygen tension during in vitro oocyte maturation and fertilization affects embryo quality in sheep and deer

    Article • Animal Reproduction Science, February 2020, Elsevier

    PhD Alfonso Gutierrez-Adan

  70. Stage-specific metabolomic changes in equine oviductal fluid: New insights into the equine fertilization environment

    Article • Theriogenology, February 2020, Elsevier

    PhD Alfonso Gutierrez-Adan

  71. Successful ICSI in Mice Using Caput Epididymal Spermatozoa

    Article • Frontiers in Cell and Developmental Biology, December 2019, Frontiers

    PhD Alfonso Gutierrez-Adan

  72. An approach to study the local embryo effect on gene expression in the bovine oviduct epithelium in vivo

    Article • Reproduction in Domestic Animals, September 2019, Wiley

    PhD Alfonso Gutierrez-Adan

  73. Global transcriptomic response of bovine endometrium to blastocyst-stage embryos

    Article • Reproduction, September 2019, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  74. Gene expression profiles of bovine genital ridges during sex determination and early differentiation of the gonads†

    Article • Biology of Reproduction, August 2019, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  75. Sex-Dimorphic Behavioral Alterations and Altered Neurogenesis in U12 Intron Splicing-Defective Zrsr1 Mutant Mice

    Article • International Journal of Molecular Sciences, July 2019, MDPI AG

    PhD Alfonso Gutierrez-Adan

  76. Gene expression and metabolic response of bovine oviduct epithelial cells to the early embryo

    Article • Reproduction, July 2019, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  77. Longitudinal analysis of somatic and germ-cell telomere dynamics in outbred mice

    Article • Molecular Reproduction and Development, June 2019, Wiley

    PhD Alfonso Gutierrez-Adan

  78. Differential isoform expression and alternative splicing in sex determination in mice

    Article • BMC Genomics, March 2019, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  79. Embryo responses to stress induced by assisted reproductive technologies

    Article • Molecular Reproduction and Development, February 2019, Wiley

    PhD Alfonso Gutierrez-Adan

  80. Seminal plasma amino acid profile in different breeds of chicken: Role of seminal plasma on sperm cryoresistance

    Article • PLOS One, January 2019, PLOS

    PhD Alfonso Gutierrez-Adan

  81. Targeting host metabolism by inhibition of acetyl-Coenzyme A carboxylase reduces flavivirus infection in mouse models

    Article • Emerging Microbes & Infections, January 2019, Taylor & Francis

    Ana-Belén Blázquez, Francisco Sobrino, PhD Alfonso Gutierrez-Adan

  82. Tissue plasminogen activator (tPA) of paternal origin is necessary for the success of in vitro but not of in vivo fertilisation in the mouse

    Article • Reproduction Fertility and Development, January 2019, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  83. Minor Splicing Factors <i>Zrsr1</i> and <i>Zrsr2</i> Essential for Gametogenesis, Early Embryo Development and Conversion of Stem Cells into 2C-Like

    Article • SSRN Electronic Journal, January 2019, Elsevier

    PhD Alfonso Gutierrez-Adan

  84. Analysis of extracellular vesicles from endometrial-derived mesenchymal stem cells

    Article • Biology of Reproduction, December 2018, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan, Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  85. EV‐endMSCs increase the developmental competence of IVF‐derived embryos from aged females

    Article • Reproduction in Domestic Animals, September 2018, Wiley

    Dr Francisco Miguel Sánchez Margallo, PhD Alfonso Gutierrez-Adan, Dr Javier G Casado

  86. Ascorbic acid-cyclodextrin complex alters the expression of genes associated with lipid metabolism in in vitro produced bovine embryos

    Article • Reproduction in Domestic Animals, August 2018, Wiley

    Viviana Torres, PhD Alfonso Gutierrez-Adan

  87. Effect of chronic THC administration in the reproductive organs of male mice, spermatozoa and in vitro fertilization

    Article • Biochemical Pharmacology, August 2018, Elsevier

    PhD Alfonso Gutierrez-Adan

  88. Effects of the HDAC inhibitor scriptaid on the in vitro development of bovine embryos and on imprinting gene expression levels

    Article • Theriogenology, April 2018, Elsevier

    PhD Alfonso Gutierrez-Adan

  89. Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice

    Article • Cell Reports, April 2018, Elsevier

    PhD Alfonso Gutierrez-Adan

  90. Resveratrol-cyclodextrin complex affects the expression of genes associated with lipid metabolism in bovine in vitro produced embryos

    Article • Reproduction in Domestic Animals, March 2018, Wiley

    PhD Alfonso Gutierrez-Adan

  91. In vitro cultured bovine endometrial cells recognize embryonic sex

    Article • Theriogenology, March 2018, Elsevier

    PhD Alfonso Gutierrez-Adan

  92. Sperm selection by thermotaxis improves ICSI outcome in mice

    Article • Scientific Reports, February 2018, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  93. Bovine oviductal and uterine fluid support in vitro embryo development

    Article • Reproduction Fertility and Development, January 2018, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  94. Effects of recombinant OVGP1 protein on in vitro bovine embryo development

    Article • Journal of Reproduction and Development, January 2018, Japanese Society of Animal Reproduction

    PhD Alfonso Gutierrez-Adan

  95. a-Tocopherol modifies the expression of genes related to oxidative stress and apoptosis during invitro maturation and enhances the developmental competence of rabbit oocytes

    Article • Reproduction Fertility and Development, January 2018, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan, Rosa María Garcia Garcia

  96. Expanded equine cumulus–oocyte complexes exhibit higher meiotic competence and lower glucose consumption than compact cumulus–oocyte complexes

    Article • Reproduction Fertility and Development, January 2018, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  97. The oviduct: from sperm selection to the epigenetic landscape of the embryo†

    Article • Biology of Reproduction, December 2017, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  98. Early sex-dependent differences in response to environmental stress

    Article • Reproduction, October 2017, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  99. Bottlenose Dolphin (Tursiops truncatus) Spermatozoa: Collection, Cryopreservation, and Heterologous In Vitro Fertilization

    Article • Journal of Visualized Experiments, August 2017, MyJove Corporation

    PhD Alfonso Gutierrez-Adan

  100. Bottlenose Dolphin (<em>Tursiops truncatus</em>) Spermatozoa: Collection, Cryopreservation, and Heterologous <em>In Vitro</em> Fertilization

    Article • Journal of Visualized Experiments, August 2017, MyJove Corporation

    PhD Alfonso Gutierrez-Adan

  101. Cultured bovine embryo biopsy conserves methylation marks from original embryo†

    Article • Biology of Reproduction, July 2017, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  102. Hepatoma-derived growth factor: Protein quantification in uterine fluid, gene expression in endometrial-cell culture and effects on in vitro embryo development, pregnancy and birth

    Article • Theriogenology, July 2017, Elsevier

    PhD Alfonso Gutierrez-Adan

  103. Subfertility in bulls carrying a nonsense mutation in TMEM95 is due to failure to interact with the oocyte vestments

    Article • Biology of Reproduction, June 2017, Oxford University Press (OUP)

    Dr Alan M O'Doherty, PhD Alfonso Gutierrez-Adan

  104. Effect of urokinase type plasminogen activator on in vitro bovine oocyte maturation

    Article • Reproduction, June 2017, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  105. CB 1 cannabinoid receptor drives oocyte maturation and embryo development via PI3K/Akt and MAPK pathways

    Article • The FASEB Journal, April 2017, Federation of American Societies For Experimental Biology (FASEB)

    PhD Alfonso Gutierrez-Adan

  106. Embryo culture in presence of oviductal fluid induces DNA methylation changes in bovine blastocysts

    Article • Reproduction, April 2017, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  107. Maternal metabolic stress may affect oviduct gatekeeper function

    Article • Reproduction, March 2017, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  108. Bovine embryo-oviduct interactionin vitroreveals an early cross talk mediated by BMP signaling

    Article • Reproduction, March 2017, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  109. Expression and localization of ARTEMIN in the bovine uterus and embryos

    Article • Theriogenology, March 2017, Elsevier

    PhD Alfonso Gutierrez-Adan

  110. Effect of bovine oviductal extracellular vesicles on embryo development and qualityin vitro

    Article • Reproduction, January 2017, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  111. Elimination of methylation marks at lysines 4 and 9 of histone 3 (H3K4 and H3K9) of spermatozoa alters offspring phenotype

    Article • Reproduction Fertility and Development, January 2017, CSIRO Publishing

    Priscila Ramos-Ibeas, PhD Alfonso Gutierrez-Adan

  112. In vivo and in vitro maturation of rabbit oocytes differently affects the gene expression profile, mitochondrial distribution, apoptosis and early embryo development

    Article • Reproduction Fertility and Development, January 2017, CSIRO Publishing

    Rosa María Garcia Garcia, PhD Alfonso Gutierrez-Adan

  113. Differential effects of high and low glucose concentrations during lipolysis-like conditions on bovine in vitro oocyte quality, metabolism and subsequent embryo development

    Article • Reproduction Fertility and Development, January 2017, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  114. Effect of bovine oviductal fluid on development and quality of bovine embryos produced in vitro

    Article • Reproduction Fertility and Development, January 2017, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  115. Effect of nutritionally induced hyperlipidaemia on in vitro bovine embryo quality depends on the type of major fatty acid in the diet

    Article • Reproduction Fertility and Development, January 2017, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  116. Short- and long-term outcomes of the absence of protein during bovine blastocyst formation in vitro

    Article • Reproduction Fertility and Development, January 2017, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  117. Biased Agonism of Three Different Cannabinoid Receptor Agonists in Mouse Brain Cortex

    Article • Frontiers in Pharmacology, November 2016, Frontiers

    PhD Alfonso Gutierrez-Adan

  118. Exocannabinoids effect on in vitro bovine oocyte maturation via activation of AKT and ERK1/2

    Article • Reproduction, October 2016, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  119. Oviductal response to gametes and early embryos in mammals

    Article • Reproduction, August 2016, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  120. Sexually Dimorphic Gene Expression in Bovine Conceptuses at the Initiation of Implantation

    Article • Biology of Reproduction, August 2016, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  121. Maternal-embryo interaction in the bovine oviduct: Evidence from in vivo and in vitro studies

    Article • Theriogenology, July 2016, Elsevier

    PhD Alfonso Gutierrez-Adan

  122. Spatial differences in gene expression in the bovine oviduct

    Article • Reproduction, April 2016, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  123. Progesterone effects on mouse sperm kinetics in conditions of viscosity

    Article • Reproduction, February 2016, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  124. Extracellular Vesicles from BOEC in In Vitro Embryo Development and Quality

    Article • PLOS One, February 2016, PLOS

    PhD Alfonso Gutierrez-Adan

  125. Suboptimal culture conditions induce more deviations in gene expression in male than female bovine blastocysts

    Article • BMC Genomics, January 2016, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  126. A novel antioxidant formulation designed to treat male infertility associated with oxidative stress: promising preclinical evidence from animal models

    Article • Human Reproduction, January 2016, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  127. Characterisation of the deleted in azoospermia like (Dazl)–green fluorescent protein mouse model generated by a two-step embryonic stem cell-based strategy to identify pluripotent and germ cells

    Article • Reproduction Fertility and Development, January 2016, CSIRO Publishing

    Priscila Ramos-Ibeas, PhD Alfonso Gutierrez-Adan

  128. Additions and Corrections

    Article • Biology of Reproduction, January 2016, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  129. Transgenic mouse offspring generated by ROSI

    Article • Journal of Reproduction and Development, January 2016, Japanese Society of Animal Reproduction

    PhD Alfonso Gutierrez-Adan

  130. Spermatozoa telomeres determine telomere length in early embryos and offspring

    Article • October 2015, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  131. Effects of Synchronous and Asynchronous Embryo Transfer on Postnatal Development, Adult Health, and Behavior in Mice1

    Article • Biology of Reproduction, October 2015, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  132. Heterologous murine and bovine IVF using bottlenose dolphin (Tursiops truncatus) spermatozoa

    Article • Theriogenology, October 2015, Elsevier

    PhD Alfonso Gutierrez-Adan

  133. Tet-mediated imprinting erasure in H19 locus following reprogramming of spermatogonial stem cells to induced pluripotent stem cells

    Article • Scientific Reports, September 2015, Nature

    Priscila Ramos-Ibeas, PhD Alfonso Gutierrez-Adan

  134. Fertilix, a novel antioxidant formulation designed to treat male infertility emanating from sperm oxidative DNA damage: promising preclinical evidence from mouse models

    Article • Fertility and Sterility, September 2015, Elsevier

    PhD Alfonso Gutierrez-Adan

  135. Oviduct-Embryo Interactions in Cattle: Two-Way Traffic or a One-Way Street?1

    Article • Biology of Reproduction, June 2015, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  136. The effect of human follicular fluid on bovine oocyte developmental competence and embryo quality

    Article • Reproductive BioMedicine Online, February 2015, Elsevier

    PhD Alfonso Gutierrez-Adan

  137. Liver growth factor induces testicular regeneration in EDS-treated rats and increases protein levels of class B scavenger receptors

    Article • AJP Endocrinology and Metabolism, January 2015, American Physiological Society

    PhD Alfonso Gutierrez-Adan

  138. Interaction between differential gene expression profile and phenotype in bovine blastocysts originating from oocytes exposed to elevated non-esterified fatty acid concentrations

    Article • Reproduction Fertility and Development, January 2015, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  139. Why we should not select the faster embryo: lessons from mice and cattle

    Article • Reproduction Fertility and Development, January 2015, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  140. Elevated non-esterified fatty acid concentrations during in vitro murine follicle growth alter follicular physiology and reduce oocyte developmental competence

    Article • Fertility and Sterility, December 2014, Elsevier

    PhD Alfonso Gutierrez-Adan

  141. Potential Health Risks Associated to ICSI: Insights from Animal Models and Strategies for a Safe Procedure

    Article • Frontiers in Public Health, November 2014, Frontiers

    Priscila Ramos-Ibeas, PhD Alfonso Gutierrez-Adan

  142. Male Fertility Is Reduced by Chronic Intermittent Hypoxia Mimicking Sleep Apnea in Mice

    Article • SLEEP, November 2014, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  143. Hyperplastic Obesity and Liver Steatosis as Long-Term Consequences of Suboptimal In Vitro Culture of Mouse Embryos1

    Article • Biology of Reproduction, August 2014, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  144. An Efficient System to Establish Biopsy-Derived Trophoblastic Cell Lines from Bovine Embryos1

    Article • Biology of Reproduction, July 2014, Oxford University Press (OUP)

    Priscila Ramos-Ibeas, PhD Alfonso Gutierrez-Adan

  145. Germ-cell culture conditions facilitate the production of mouse embryonic stem cells

    Article • Molecular Reproduction and Development, June 2014, Wiley

    Priscila Ramos-Ibeas, PhD Alfonso Gutierrez-Adan

  146. Ghrelin AcceleratesIn VitroMaturation of Bovine Oocytes

    Article • Reproduction in Domestic Animals, June 2014, Wiley

    Georgios S. Amiridis , PhD Alfonso Gutierrez-Adan

  147. Intracytoplasmic Sperm Injection Using DNA-Fragmented Sperm in Mice Negatively Affects Embryo-Derived Embryonic Stem Cells, Reduces the Fertility of Male Offspring and Induces Heritable Changes in Epialleles

    Article • PLOS One, April 2014, PLOS

    Priscila Ramos-Ibeas, PhD Alfonso Gutierrez-Adan

  148. Local Activation of Uterine Toll-Like Receptor 2 and 2/6 Decreases Embryo Implantation and Affects Uterine Receptivity in Mice1

    Article • Biology of Reproduction, April 2014, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  149. Daily supplementation with ghrelin improves in vitro bovine blastocysts formation rate and alters gene expression related to embryo quality

    Article • Theriogenology, March 2014, Elsevier

    PhD Alfonso Gutierrez-Adan

  150. Effects of vitrification on the expression of pluripotency, apoptotic and stress genes in in vitro-produced porcine blastocysts

    Article • Reproduction Fertility and Development, January 2014, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  151. Transcriptome profiling of liver of non-genetic low birth weight and long term health consequences

    Article • BMC Genomics, January 2014, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  152. Role of the Goat K222-PrPC Polymorphic Variant in Prion Infection Resistance

    Article • Journal of Virology, December 2013, ASM Journals

    PhD Alfonso Gutierrez-Adan

  153. Spontaneous Generation of Infectious Prion Disease in Transgenic Mice

    Article • Emerging Infectious Diseases, December 2013, Centers for Disease Control and Prevention (CDC)

    PhD Alfonso Gutierrez-Adan

  154. Embryo gene expression in response to maternal supplementation with glycogenic precursors in the rabbit

    Article • Animal Reproduction Science, November 2013, Elsevier

    Dr Antonio Gonzalez-Bulnes, Rosa María Garcia Garcia, PhD Alfonso Gutierrez-Adan

  155. Most regions of mouse epididymis are able to phagocytose immature germ cells

    Article • Reproduction, August 2013, Bioscientifica

    Priscila Ramos-Ibeas, PhD Alfonso Gutierrez-Adan

  156. Treatment with cholesterol-loaded methyl-β-cyclodextrin increased the cholesterol in rabbit oocytes, but did not improve developmental competence of cryopreserved oocytes

    Article • Cryobiology, August 2013, Elsevier

    Dr EVA MOCÉ, PhD Alfonso Gutierrez-Adan

  157. The role of prion protein in stem cell regulation

    Article • Reproduction, June 2013, Bioscientifica

    Priscila Ramos-Ibeas, PhD Alfonso Gutierrez-Adan

  158. 250 ALL REGIONS OF THE MOUSE EPIDIDYMIS ARE ABLE TO PHAGOCYTIZE IMMATURE SPERMATOGENIC CELLS

    Article • Reproduction Fertility and Development, January 2013, CSIRO Publishing

    Priscila Ramos-Ibeas, PhD Alfonso Gutierrez-Adan

  159. Sex-specific embryonic origin of postnatal phenotypic variability

    Article • Reproduction Fertility and Development, January 2013, CSIRO Publishing

    Priscila Ramos-Ibeas, PhD Alfonso Gutierrez-Adan

  160. Ovarian response and embryo gene expression patterns after nonsuperovulatory gonadotropin stimulation in primiparous rabbits does

    Article • Theriogenology, January 2013, Elsevier

    Rosa María Garcia Garcia, PhD Alfonso Gutierrez-Adan

  161. Acute fasting before conception affects metabolic and endocrine status without impacting follicle and oocyte development and embryo gene expression in the rabbit

    Article • Reproduction Fertility and Development, January 2013, CSIRO Publishing

    Rosa María Garcia Garcia, PhD Alfonso Gutierrez-Adan

  162. Behavioral, neurochemical and morphological changes induced by the overexpression of munc18-1a in brain of mice: relevance to schizophrenia

    Article • Translational Psychiatry, January 2013, Springer Science + Business Media

    Javier Pascau, PhD Alfonso Gutierrez-Adan

  163. 91 SPERMATOZOA TELOMERE LENGTH DETERMINES EMBRYONIC TELOMERE LENGTH BEFORE EMBRYONIC GENOME ACTIVATION

    Article • Reproduction Fertility and Development, January 2013, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  164. Oocyte developmental failure in response to elevated nonesterified fatty acid concentrations: mechanistic insights

    Article • October 2012, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  165. HSL-knockout mouse testis exhibits class B scavenger receptor upregulation and disrupted lipid raft microdomains

    Article • Journal of Lipid Research, September 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Alfonso Gutierrez-Adan

  166. Effect of the Bovine Oviductal Fluid onIn VitroFertilization, Development and Gene Expression ofIn Vitro-Produced Bovine Blastocysts

    Article • Reproduction in Domestic Animals, August 2012, Wiley

    PhD Alfonso Gutierrez-Adan

  167. Male Mice Produced by In Vitro Culture Have Reduced Fertility and Transmit Organomegaly and Glucose Intolerance to Their Male Offspring1

    Article • Biology of Reproduction, August 2012, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  168. The Use of Intracytoplasmic Sperm Injection (ICSI) for Gene Transfer in Mice

    Article • May 2012, Bentham Science Publishers

    PhD Alfonso Gutierrez-Adan

  169. Solving the “X” in Embryos and Stem Cells

    Article • Stem Cells and Development, May 2012, Mary Ann Liebert Inc

    Priscila Ramos-Ibeas, PhD Alfonso Gutierrez-Adan

  170. Long-term and transgenerational effects of in vitro culture on mouse embryos

    Article • Theriogenology, March 2012, Elsevier

    Priscila Ramos-Ibeas, PhD Alfonso Gutierrez-Adan

  171. Sex determination of porcine embryos using a new developed duplex polymerase chain reaction procedure based on the amplification of repetitive sequences

    Article • Reproduction Fertility and Development, January 2012, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  172. In vitro and in vivo development of mice morulae after storage in non-frozen conditions

    Article • Reproductive Biology and Endocrinology, January 2012, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  173. Intrafollicular conditions as a major link between maternal metabolism and oocyte quality: a focus on dairy cow fertility

    Article • Reproduction Fertility and Development, January 2012, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  174. Reduced Mid1 Expression and Delayed Neuromotor Development in daDREAM Transgenic Mice

    Article • Frontiers in Molecular Neuroscience, January 2012, Frontiers

    PhD Alfonso Gutierrez-Adan

  175. 60 TELOMERE LENGTH DYNAMICS DURING BOVINE PREIMPLANTATION EMBRYO DEVELOPMENT

    Article • Reproduction Fertility and Development, January 2012, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  176. Effect of leptin during in vitro maturation of prepubertal calf oocytes: Embryonic development and relative mRNA abundances of genes involved in apoptosis and oocyte competence

    Article • Theriogenology, December 2011, Elsevier

    PhD Alfonso Gutierrez-Adan

  177. Factors affecting porcine sperm mediated gene transfer

    Article • Research in Veterinary Science, December 2011, Elsevier

    PhD Alfonso Gutierrez-Adan

  178. Comparison of four methods to evaluate sperm DNA integrity between mouse caput and cauda epididymidis

    Article • Asian Journal of Andrology, October 2011, Medknow

    PhD Alfonso Gutierrez-Adan

  179. Altered gene transcription and telomere length in trout embryo and larvae obtained with DNA cryodamaged sperm

    Article • Theriogenology, October 2011, Elsevier

    Professor Maria Paz Herraez, PhD Alfonso Gutierrez-Adan

  180. Single in vitro bovine embryo production: Coculture with autologous cumulus cells, developmental competence, embryo quality and gene expression profiles

    Article • Theriogenology, October 2011, Elsevier

    PhD Alfonso Gutierrez-Adan

  181. New Challenges in the Analysis of Gene Transcription in Bovine Blastocysts

    Article • Reproduction in Domestic Animals, August 2011, Wiley

    PhD Alfonso Gutierrez-Adan

  182. Elevated Non-Esterified Fatty Acid Concentrations during Bovine Oocyte Maturation Compromise Early Embryo Physiology

    Article • PLOS One, August 2011, PLOS

    PhD Alfonso Gutierrez-Adan

  183. Transcriptome Changes at the Initiation of Elongation in the Bovine Conceptus1

    Article • Biology of Reproduction, August 2011, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  184. Prion protein in ESC regulation

    Article • Prion, July 2011, Taylor & Francis

    PhD Alfonso Gutierrez-Adan

  185. Transcriptional sexual dimorphism in elongating bovine embryos: implications for XCI and sex determination genes

    Article • Reproduction, June 2011, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  186. Transcriptional sexual dimorphism during preimplantation embryo development and its consequences for developmental competence and adult health and disease

    Article • Reproduction, May 2011, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  187. Prion Protein Expression Regulates Embryonic Stem Cell Pluripotency and Differentiation

    Article • PLOS One, April 2011, PLOS

    PhD Alfonso Gutierrez-Adan

  188. Sheep and Goat BSE Propagate More Efficiently than Cattle BSE in Human PrP Transgenic Mice

    Article • PLoS Pathogens, March 2011, PLOS

    Dr Vincent Beringue, PhD Alfonso Gutierrez-Adan

  189. Effect of leptin supplementation during in vitro oocyte maturation and embryo culture on bovine embryo development and gene expression patterns

    Article • Theriogenology, March 2011, Elsevier

    PhD Alfonso Gutierrez-Adan

  190. Effects of Guaiazulene on In Vitro Bovine Embryo Production and on mRNA Transcripts Related to Embryo Quality

    Article • Reproduction in Domestic Animals, February 2011, Wiley

    PhD Alfonso Gutierrez-Adan

  191. Postnatal Effects of Sperm Chromatin Damage

    Article • January 2011, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  192. Effect of liver growth factor on both testicular regeneration and recovery of spermatogenesis in busulfan-treated mice

    Article • Reproductive Biology and Endocrinology, January 2011, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  193. 273 CONSEQUENCE OF HIGH NONESTERIFIED FATTY ACID CONCENTRATIONS DURING BOVINE OOCYTE IN VITRO MATURATION ON mRNA TRANSCRIPT ABUNDANCE OF BLASTOCYSTS

    Article • Reproduction Fertility and Development, January 2011, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  194. 88 EFFECT OF VITRIFICATION PROCEDURE ON SURVIVAL RATE OF BOVINE EMBRYOS PRODUCED IN VITRO

    Article • Reproduction Fertility and Development, January 2011, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  195. 181 TRANSCRIPTIONAL SEXUAL DIMORPHISM IN AUTOSOMAL GENES ON BOVINE DAY 14 EMBRYOS

    Article • Reproduction Fertility and Development, January 2011, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  196. Effect of long-term culture of mouse embryonic stem cells under low oxygen concentration as well as on glycosaminoglycan hyaluronan on cell proliferation and differentiation

    Article • Cell Proliferation, December 2010, Wiley

    PhD Alfonso Gutierrez-Adan

  197. Histone Modifications at the Blastocyst Axin1Fu Locus Mark the Heritability of In Vitro Culture-Induced Epigenetic Alterations in Mice1

    Article • Biology of Reproduction, November 2010, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  198. Production of transgenic piglets using ICSI–sperm-mediated gene transfer in combination with recombinase RecA

    Article • Reproduction, August 2010, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  199. Oviductal secretions: will they be key factors for the future ARTs?

    Article • Molecular Human Reproduction, June 2010, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  200. Effect of exogenous DNA on bovine sperm functionality using the sperm mediated gene transfer (SMGT) technique

    Article • Molecular Reproduction and Development, June 2010, Wiley

    PhD Alfonso Gutierrez-Adan

  201. Depression-resistant endophenotype in mice overexpressing cannabinoid CB2 receptors

    Article • Bone Marrow Transplantation, April 2010, Wiley

    PhD Alfonso Gutierrez-Adan

  202. Culture of bovine embryos in intermediate host oviducts with emphasis on the isolated mouse oviduct

    Article • Theriogenology, April 2010, Elsevier

    PhD Alfonso Gutierrez-Adan

  203. Low oxygen tension during IVM improves bovine oocyte competence and enhances anaerobic glycolysis

    Article • Reproductive BioMedicine Online, March 2010, Elsevier

    PhD Alfonso Gutierrez-Adan

  204. Sex determines the expression level of one third of the actively expressed genes in bovine blastocysts

    Article • Proceedings of the National Academy of Sciences, February 2010, Proceedings of the National Academy of Sciences

    PhD Alfonso Gutierrez-Adan

  205. Effect of genistein supplementation of thawing medium on characteristics of frozen human spermatozoa

    Article • Asian Journal of Andrology, February 2010, Medknow

    PhD Alfonso Gutierrez-Adan

  206. Amino acid metabolism of bovine blastocysts: a biomarker of sex and viability

    Article • Molecular Reproduction and Development, January 2010, Wiley

    PhD Alfonso Gutierrez-Adan

  207. Developmental kinetics and gene expression in male and female bovine embryos producedin vitrowith sex-sorted spermatozoa

    Article • Reproduction Fertility and Development, January 2010, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  208. Selection against spermatozoa with fragmented DNA after postovulatory mating depends on the type of damage

    Article • Reproductive Biology and Endocrinology, January 2010, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  209. 233 DIFFERENTIAL GENE EXPRESSION IN BOVINE BLASTOCYSTS AND ELONGATING CONCEPTUSES DERIVED IN VIVO OR IN VITRO

    Article • Reproduction Fertility and Development, January 2010, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  210. 2 IDENTIFICATION OF FIVE GENES EXPRESSED PREFERENTIALLY FROM THE PATERNAL X CHROMOSOME

    Article • Reproduction Fertility and Development, January 2010, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  211. Intrafollicular testosterone concentration and sex ratio in individually cultured bovine embryos

    Article • Reproduction Fertility and Development, January 2010, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  212. 374 SEX-DEPENDENT METABOLIC DIFFERENCES OF BOVINE PREIMPLANTATION EMBRYOS

    Article • Reproduction Fertility and Development, January 2010, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  213. The effect of bovine embryo culture without proteins supplements until day 4 on transcription level of hyaluronan synthases, receptors and mtDNA content

    Article • Zygote, December 2009, Cambridge University Press

    PhD Alfonso Gutierrez-Adan

  214. The effect of nutritionally induced hyperlipidaemia on in vitro bovine embryo quality

    Article • Human Reproduction, December 2009, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  215. Effect of sperm treatment on efficiency of EGFP-expressing porcine embryos produced by ICSI-SMGT

    Article • Theriogenology, September 2009, Elsevier

    PhD Alfonso Gutierrez-Adan

  216. Progesterone and conceptus elongation in cattle: a direct effect on the embryo or an indirect effect via the endometrium?

    Article • Reproduction, September 2009, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  217. Changes in testosterone or temperature during the in vitro oocyte culture do not alter the sex ratio of bovine embryos

    Article • Journal of Experimental Zoology Part A Ecological Genetics and Physiology, July 2009, Wiley

    PhD Alfonso Gutierrez-Adan

  218. Effect of Stem Cell Activation, Culture Media of Manipulated Embryos, and Site of Embryo Transfer in the Production of F0 Embryonic Stem Cell Mice1

    Article • Biology of Reproduction, June 2009, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  219. Effects of oviductal fluid on the development, quality, and gene expression of porcine blastocysts produced in vitro

    Article • Reproduction, April 2009, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  220. Analysis of gene transcription alterations at the blastocyst stage related to the long-term consequences of in vitro culture in mice

    Article • Reproduction, February 2009, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  221. Biological differences between in vitro produced bovine embryos and parthenotes

    Article • Reproduction, February 2009, Bioscientifica

    PhD Alfonso Gutierrez-Adan

  222. Gene Expression in Early Expanded Parthenogenetic and In Vitro Fertilized Bovine Blastocysts

    Article • Journal of Reproduction and Development, January 2009, Japanese Society of Animal Reproduction

    PhD Alfonso Gutierrez-Adan

  223. 121 DIFFERENTIAL mRNA EXPRESSION BETWEEN IN VIVO AND IN VITRO-DERIVED BOS INDICUS AND BOS TAURUS EMBRYOS

    Article • Reproduction Fertility and Development, January 2009, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  224. 1 EFFECT OF OXYGEN TENSION DURING IN VITRO MATURATION AND FERTILIZATION ON BOVINE EMBRYO PRODUCTION AND CUMULUS-OOCYTE-COMPLEX mRNA ABUNDANCE

    Article • Reproduction Fertility and Development, January 2009, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  225. 303 EFFECT OF THE PRESENCE OF EXOGENOUS DNA AND RECOMBINASE-A PROTEIN ON THE BOAR SPERM FUNCTIONALITY

    Article • Reproduction Fertility and Development, January 2009, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  226. 112 EFFECTS OF GUAIAZULENE ON IN VITRO CULTURE OF BOVINE ZYGOTES, AND ON mRNA TRANSCRIPTS RELATED TO EMBRYO QUALITY

    Article • Reproduction Fertility and Development, January 2009, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  227. Evaluación de la unión espermatozoide-ADN exógeno en espermatozoides porcinos eyaculados y epididimarios

    Article • Archivos de medicina veterinaria, January 2009, SciELO Comision Nacional de Investigacion Cientifica Y Tecnologica (CONICYT)

    PhD Alfonso Gutierrez-Adan

  228. 204 RELATIVE MESSENGER RNA ABUNDANCE OF HYALURONAN RECEPTORS AND SYNTHASES ON IN VITRO- AND IN VIVO-DERIVED DAY 7 AND DAY 13 BOVINE EMBRYOS

    Article • Reproduction Fertility and Development, January 2009, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  229. 264 TESTOSTERONE IN THE OOCYTE CULTURE DOES NOT ALTER SEX-RATIO OF IN VITRO PRODUCED BOVINE EMBRYOS

    Article • Reproduction Fertility and Development, January 2009, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  230. The effect of different zwitterionic buffers and PBS used for out-of-incubator procedures during standard in vitro embryo production on development, morphology and gene expression of bovine embryos

    Article • Theriogenology, December 2008, Elsevier

    PhD Alfonso Gutierrez-Adan

  231. Crucial Role of CB2 Cannabinoid Receptor in the Regulation of Central Immune Responses during Neuropathic Pain

    Article • Journal of Neuroscience, November 2008, Society for Neuroscience

    PhD Alfonso Gutierrez-Adan

  232. Interferon-  Is a Critical Modulator of CB2 Cannabinoid Receptor Signaling during Neuropathic Pain

    Article • Journal of Neuroscience, November 2008, Society for Neuroscience

    PhD Alfonso Gutierrez-Adan

  233. Can Bovine In Vitro-Matured Oocytes Selectively Process X- or Y-Sorted Sperm Differentially?1

    Article • Biology of Reproduction, October 2008, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  234. Consequences ofIn VitroCulture Conditions on Embryo Development and Quality

    Article • Reproduction in Domestic Animals, October 2008, Wiley

    PhD Alfonso Gutierrez-Adan

  235. Can Bovine In Vitro Matured Oocytes Process Differentially X- or Y-bearing Spermatozoa?

    Article • Biology of Reproduction, May 2008, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  236. Effect of Oxygen Tension on Embryo Development and Gene Transcription of Bovine Blastocysts Produced In Vitro by Co-culture with Oviduct Epithelial Cells.

    Article • Biology of Reproduction, May 2008, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  237. Long-Term Effects of Mouse Intracytoplasmic Sperm Injection with DNA-Fragmented Sperm on Health and Behavior of Adult Offspring1

    Article • Biology of Reproduction, April 2008, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  238. Development, molecular composition and freeze tolerance of bovine embryos cultured in TCM-199 supplemented with hyaluronan

    Article • Zygote, January 2008, Cambridge University Press

    PhD Alfonso Gutierrez-Adan

  239. Effect of duration of oocyte maturation on the kinetics of cleavage, embryo yield and sex ratio in cattle

    Article • Reproduction Fertility and Development, January 2008, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  240. Epigenetic differences between male and female bovine blastocysts produced in vitro

    Article • Physiological Genomics, January 2008, American Physiological Society

    PhD Alfonso Gutierrez-Adan

  241. 197 DOES DURATION OF BOVINE OOCYTE MATURATION IN VITRO AFFECT THE SPEED OF EMBRYO DEVELOPMENT IN VITRO AND SEX RATIO AT THE TWO-CELL OR BLASTOCYST STAGE?

    Article • Reproduction Fertility and Development, January 2008, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  242. 301 EVALUATION OF THE SPERM-MEDIATED GENE TRANSFER (SMGT) TECHNIQUE BY IN VITRO FERTILIZATION IN PIGS USING RecA PROTEIN

    Article • Reproduction Fertility and Development, January 2008, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  243. 183 THE EFFECT OF BOVINE EMBRYO CULTURE WITHOUT ANY PROTEIN SOURCES UNTIL DAY 4 ON TRANSCRIPTION OF HYALURONAN SYNTHASES AND RECEPTORS AND mtDNA CONTENT

    Article • Reproduction Fertility and Development, January 2008, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  244. Factors From Damaged Sperm Affect Its DNA Integrity and Its Ability to Promote Embryo Implantation in Mice

    Article • Journal of Andrology, August 2007, Wiley

    PhD Alfonso Gutierrez-Adan

  245. TRANSGENERATIONAL EPIGENETIC ALTERATIONS IN MICE PRODUCED BY IN VITRO CULTURE

    Article • Biology of Reproduction, July 2007, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  246. Reduced susceptibility to bovine spongiform encephalopathy prions in transgenic mice expressing a bovine PrP with five octapeptide repeats

    Article • Journal of General Virology, June 2007, Society for General Microbiology

    PhD Alfonso Gutierrez-Adan

  247. Suboptimal in vitro culture conditions: an epigenetic origin of long-term health effects

    Article • Molecular Reproduction and Development, May 2007, Wiley

    PhD Alfonso Gutierrez-Adan

  248. Improving the generation of genomic-type transgenic mice by ICSI

    Article • Transgenic Research, February 2007, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  249. Effect of Transgene Concentration, Flanking Matrix Attachment Regions, and RecA-Coating on the Efficiency of Mouse Transgenesis Mediated by Intracytoplasmic Sperm Injection1

    Article • Biology of Reproduction, February 2007, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  250. Scrotal heat stress effects on sperm viability, sperm DNA integrity, and the offspring sex ratio in mice

    Article • Molecular Reproduction and Development, January 2007, Wiley

    PhD Alfonso Gutierrez-Adan

  251. Development and pattern of mRNA relative abundance of bovine embryos cultured in the isolated mouse oviduct in organ culture

    Article • Molecular Reproduction and Development, January 2007, Wiley

    PhD Alfonso Gutierrez-Adan

  252. Inadvertent presence of pluripotent cells in monolayers derived from differentiated embryoid bodies

    Article • The International Journal of Developmental Biology, January 2007, UBC Press

    PhD Alfonso Gutierrez-Adan

  253. 375 UNEXPECTED SEVERE ABNORMALITIES IN MOUSE ROSI OFFSPRING

    Article • Reproduction Fertility and Development, January 2007, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  254. 401 USE OF FLOW CYTOMETRY TO EVALUATE THE CAPACITY OF BOAR SPERM TO BIND TO EXOGENOUS DNA OF DIFFERENT SIZES

    Article • Reproduction Fertility and Development, January 2007, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  255. Developmental Consequences of Sexual Dimorphism During Pre-implantation Embryonic Development

    Article • Reproduction in Domestic Animals, October 2006, Wiley

    PhD Alfonso Gutierrez-Adan

  256. Sustained leukaemic phenotype after inactivation of BCR-ABLp190 in mice

    Article • Oncogene, September 2006, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  257. Effects of hyaluronan, BSA, and serum on bovine embryo in vitro development, ultrastructure, and gene expression patterns

    Article • Molecular Reproduction and Development, August 2006, Wiley

    PhD Alfonso Gutierrez-Adan

  258. P1–077: Generation of a transgenic YAC mouse as a tool for the study of sporadic Alzheimer's disease

    Article • Alzheimer s & Dementia, July 2006, Wiley

    PhD Alfonso Gutierrez-Adan

  259. Differential effects of culture and nuclear transfer on relative transcript levels of genes with key roles during preimplantation

    Article • Zygote, February 2006, Cambridge University Press

    PhD Alfonso Gutierrez-Adan

  260. SLUG (SNAI2) overexpression in embryonic development

    Article • Cytogenetic and Genome Research, January 2006, Karger Publishers

    PhD Alfonso Gutierrez-Adan

  261. Article • Reproductive Biology and Endocrinology, January 2006, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  262. Article • Reproductive Biology and Endocrinology, January 2006, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  263. Differential sensitivity of male and female mouse embryos to oxidative induced heat-stress is mediated by glucose-6-phosphate dehydrogenase gene expression

    Article • Molecular Reproduction and Development, December 2005, Wiley

    PhD Alfonso Gutierrez-Adan

  264. Downstream Regulatory Element Antagonist Modulator Regulates Ca2+ Homeostasis and Viability in Cerebellar Neurons

    Article • Journal of Neuroscience, November 2005, Society for Neuroscience

    PhD Alfonso Gutierrez-Adan

  265. Transgenic mice expressing bovine PrP with a four extra repeat octapeptide insert mutation show a spontaneous, non-transmissible, neurodegenerative disease and an expedited course of BSE infection

    Article • FEBS Letters, October 2005, Wiley

    PhD Alfonso Gutierrez-Adan

  266. Cancer development induced by graded expression of Snail in mice

    Article • Human Molecular Genetics, October 2005, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  267. Transcriptional repressor DREAM regulates T-lymphocyte proliferation and cytokine gene expression

    Article • The EMBO Journal, September 2005, Wiley

    Jose Naranjo, PhD Alfonso Gutierrez-Adan

  268. The epigenetic environment: secondary sex ratio depends on differential survival in embryogenesis: Comment 1

    Article • Human Reproduction, September 2005, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  269. Inadvertent transgenesis by conventional ICSI in mice

    Article • Human Reproduction, August 2005, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  270. Vertical Transmission of Bovine Spongiform Encephalopathy Prions Evaluated in a Transgenic Mouse Model

    Article • Journal of Virology, July 2005, ASM Journals

    PhD Alfonso Gutierrez-Adan

  271. Relationship between non-return rate and chromatin condensation of deep frozen bull spermatozoa

    Article • Theriogenology, July 2005, Elsevier

    PhD Alfonso Gutierrez-Adan

  272. SLUG in cancer development

    Article • Oncogene, February 2005, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  273. Efficient Generation of Transgenic Mice with Intact Yeast Artificial Chromosomes by Intracytoplasmic Sperm Injection1

    Article • Biology of Reproduction, December 2004, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  274. Retinoid-dependent mRNA expression and poly-(A) contents in bovine oocytes meiotically arrested and/or matured in vitro

    Article • Molecular Reproduction and Development, July 2004, Wiley

    PhD Alfonso Gutierrez-Adan

  275. Effect of speed of development on mRNA expression pattern in early bovine embryos cultured in vivo or in vitro

    Article • Molecular Reproduction and Development, June 2004, Wiley

    PhD Alfonso Gutierrez-Adan

  276. Subclinical Bovine Spongiform Encephalopathy Infection in Transgenic Mice Expressing Porcine Prion Protein

    Article • Journal of Neuroscience, May 2004, Society for Neuroscience

    PhD Alfonso Gutierrez-Adan

  277. Long-term effect of in vitro culture of mouse embryos with serum on mRNA expression of imprinting genes, development, and behavior

    Article • Proceedings of the National Academy of Sciences, April 2004, Proceedings of the National Academy of Sciences

    PhD Alfonso Gutierrez-Adan

  278. Different Behavior toward Bovine Spongiform Encephalopathy Infection of Bovine Prion Protein Transgenic Mice with One Extra Repeat Octapeptide Insert Mutation

    Article • Journal of Neuroscience, March 2004, Society for Neuroscience

    PhD Alfonso Gutierrez-Adan

  279. Search for the Bovine Homolog of the Murine Ped Gene and Characterization of Its Messenger RNA Expression During Bovine Preimplantation Development1

    Article • Biology of Reproduction, February 2004, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  280. Species-related differences in blastocyst quality are associated with differences in relative mRNA transcription

    Article • Molecular Reproduction and Development, January 2004, Wiley

    PhD Alfonso Gutierrez-Adan

  281. Relative messenger RNA abundance in bovine oocytes collected in vitro or in vivo before and 20 hr after the preovulatory luteinizing hormone surge

    Article • Molecular Reproduction and Development, September 2003, Wiley

    PhD Alfonso Gutierrez-Adan

  282. Experimental demonstration that pre- and post-conceptional mechanisms influence sex ratio in mouse embryos

    Article • Molecular Reproduction and Development, August 2003, Wiley

    PhD Alfonso Gutierrez-Adan

  283. Effect of ejaculate, bull, and a double swim-up sperm processing method on sperm sex ratio

    Article • Zygote, August 2003, Cambridge University Press

    PhD Alfonso Gutierrez-Adan

  284. Oocyte and Embryo Quality: Effect of Origin, Culture Conditions and Gene Expression Patterns

    Article • Reproduction in Domestic Animals, August 2003, Wiley

    PhD Alfonso Gutierrez-Adan

  285. Mouse ICSI with frozen-thawed sperm: The impact of sperm freezing procedure and sperm donor strain

    Article • Molecular Reproduction and Development, July 2003, Wiley

    PhD Alfonso Gutierrez-Adan

  286. Temporal Divergence in the Pattern of Messenger RNA Expression in Bovine Embryos Cultured from the Zygote to Blastocyst Stage In Vitro or In Vivo

    Article • Biology of Reproduction, May 2003, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  287. Hyperglycemia-induced apoptosis affects sex ratio of bovine and murine preimplantation embryos

    Article • Molecular Reproduction and Development, April 2003, Wiley

    PhD Alfonso Gutierrez-Adan

  288. Early detection of PrP res in BSE-infected bovine PrP transgenic mice

    Article • Archives of Virology, March 2003, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  289. Bovine Embryo Culture in the Presence or Absence of Serum: Implications for Blastocyst Development, Cryotolerance, and Messenger RNA Expression1

    Article • Biology of Reproduction, January 2003, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  290. Effect of culture environment on embryo quality and gene expression – experience from animal studies

    Article • Reproductive BioMedicine Online, January 2003, Elsevier

    PhD Alfonso Gutierrez-Adan

  291. Expression of the FUS domain restores liposarcoma development in CHOP transgenic mice

    Article • Oncogene, March 2002, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  292. Analysis of Differential Messenger RNA Expression Between Bovine Blastocysts Produced in Different Culture Systems: Implications for Blastocyst Quality1

    Article • Biology of Reproduction, March 2002, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  293. CMV-driven expression of green fluorescent protein (GFP) in male germ cells of transgenic mice and its effect on fertility

    Article • International Journal of Andrology, October 2001, Wiley

    PhD Alfonso Gutierrez-Adan

  294. Effect of the in vitro culture system on the kinetics of blastocyst development and sex ratio of bovine embryos

    Article • Theriogenology, March 2001, Elsevier

    PhD Alfonso Gutierrez-Adan

  295. Hematopoietic Stem Cell Transplantation in Utero Produces Sheep–Goat Chimeras

    Article • Blood Cells Molecules and Diseases, January 2001, Elsevier

    PhD Alfonso Gutierrez-Adan

  296. Influence of glucose on the sex ratio of bovine IVM/IVF embryos cultured in vitro

    Article • Reproduction Fertility and Development, January 2001, CSIRO Publishing

    PhD Alfonso Gutierrez-Adan

  297. The chimeric FUS/TLS-CHOP fusion protein specifically induces liposarcomas in transgenic mice

    Article • Oncogene, May 2000, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  298. Differential expression of two genes located on the X chromosome between male and female in vitro-produced bovine embryos at the blastocyst stage

    Article • Molecular Reproduction and Development, February 2000, Wiley

    PhD Alfonso Gutierrez-Adan

  299. Article • Transgenic Research, January 2000, Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan

  300. Relationship between time of first cleavage and the expression of IGF-I growth factor, its receptor, and two housekeeping genes in bovine two-cell embryos and blastocysts produced in vitro

    Article • Molecular Reproduction and Development, January 2000, Wiley

    PhD Alfonso Gutierrez-Adan

  301. Expression of bovine β-lactoglobulin transgenic mice

    Article • Journal of Dairy Research, May 1999, Cambridge University Press

    PhD Alfonso Gutierrez-Adan

  302. Relationship between sex ratio and time of insemination according to both time of ovulation and maturational state of oocyte

    Article • Zygote, February 1999, Cambridge University Press

    PhD Alfonso Gutierrez-Adan

  303. Effect of flanking matrix attachment regions on the expression of microinjected transgenes during preimplantation development of mouse embryos

    Article • Theriogenology, January 1999, Elsevier

    PhD Alfonso Gutierrez-Adan

  304. Effect of post-thaw cell rehydration at 4 °C on survival of frozen and vitrified IVP-derived bovine embryos

    Article • Reproduction Nutrition Développement, January 1999, EDP Sciences

    PhD Alfonso Gutierrez-Adan

  305. Relationship between sex ratio and time of insemination according to both time of ovulation and maturational state of oocyte

    Article • Theriogenology, January 1999, Elsevier

    PhD Alfonso Gutierrez-Adan

  306. Transgenesis in large domestic species: future development for milk modification

    Article • Reproduction Nutrition Développement, January 1999, EDP Sciences

    PhD Alfonso Gutierrez-Adan

  307. Superovulatory response of murciana goats to treatments based on PMSG/anti-PMSG or combined FSH/PMSG administration

    Article • Theriogenology, August 1998, Elsevier

    PhD Alfonso Gutierrez-Adan

  308. Isolation of Pluripotent Stem Cells from Cultured Porcine Primordial Germ Cells1

    Article • Biology of Reproduction, November 1997, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan

  309. Influence of the synchronization treatment on the superovulatory response of Murciana goats

    Article • Small Ruminant Research, January 1997, Elsevier

    PhD Alfonso Gutierrez-Adan

  310. Relationship between stage of development and sex of bovine IVM-IVF embryos cultured in vitro versus in the sheep oviduct

    Article • Theriogenology, August 1996, Elsevier

    PhD Alfonso Gutierrez-Adan

  311. Influence of biopsy sexing andin vitroculture on losses of female mouse and bovine embryos

    Article • Animal Biotechnology, October 1995, Taylor & Francis

    PhD Alfonso Gutierrez-Adan

  312. Comparison of superovulatory response of mature outbred mice treated with FSH or PMSG and developmental potential of embryos produced

    Article • Theriogenology, January 1994, Elsevier

    PhD Alfonso Gutierrez-Adan

  313. Ram spermatozoa cocultured with epithelial cell monolayers: An in vitro model for the study of capacitation and the acrosome reaction

    Article • Molecular Reproduction and Development, November 1993, Wiley

    PhD Alfonso Gutierrez-Adan

  314. Transient inhibition of foot-and-mouth disease virus infection of BHK-21 cells by antisense oligonucleotides directed against the second functional initiator AUG

    Article • Antiviral Research, September 1993, Elsevier

    PhD Alfonso Gutierrez-Adan

  315. In vitro survival of murine morulae after quick freezing in the presence of chemically defined macromolecules and different cryoprotectants

    Article • Theriogenology, May 1993, Elsevier

    PhD Alfonso Gutierrez-Adan

  316. Generation of Yeast Artificial Chromosome Transgenic Mice by Intracytoplasmic Sperm Injection

    Article • Springer Science + Business Media

    PhD Alfonso Gutierrez-Adan