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This case report details the treatment of two teens with APS-1 and stage 2 type 1 diabetes. The application of immune therapy with teplizumab to APS-1 has not bee previously described. Information about treatment, and clinical responses are provided. Information about immune responses ad pancreatic imaging are provided for one individual.

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This page is a summary of: Use of Teplizumab to Modulate Stage 2 Type 1 Diabetes in Two Individuals With Autoimmune Polyendocrine Syndrome 1, Diabetes Care, November 2025, American Diabetes Association,
DOI: 10.2337/dc25-1444.
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