All Stories

  1. A biomaterial-based platform of pancreatic cancer reveals kallikrein-related peptidase 6 (KLK6) as a mediator of neutrophil recruitment and immunosuppression
  2. In Vitro Characterization of the Published Glypican-3-Targeting Peptide TJ12P2 Reveals a Lack of Specificity and Potency
  3. Novel Ruthenacarborane–NSAID Conjugates
  4. “Precision on Two Wheels”─Structural Refinement of 64 Cu- and 68 Ga-Labeled Bicyclic Peptides Targeting Nectin-4 for Improved Tumor Imaging: From Prec...
  5. Investigation of the Putative Relationship Between Copper Transport and the Anticancer Activity of Cisplatin in Ductal Pancreatic Adenocarcinoma
  6. Radioresistant mouse pheochromocytoma cell lines
  7. Exploring the Role of Peripheral Macrophages in Glioma Progression: The Metabolic Significance of Cyclooxygenase-2 (COX-2)
  8. It’s a match: use of the radionuclide theranostic pair 133La/225Ac for the radiopharmacological characterization of EGFR-targeted single-domain antibodies
  9. Front Cover: Carborane‐Based Analogs of Celecoxib and Flurbiprofen, their COX Inhibition Potential, and COX Selectivity Index (ChemMedChem 11/2025)
  10. Cover Feature: Advances in Diclofenac Derivatives: Exploring Carborane‐Substituted N‐Methyl and Nitrile Analogs for Anticancer Therapy (ChemMedChem 11/2025)
  11. Deciphering the Tumor Uptake of Heterobivalent (SST2/Albumin) [64Cu]Cu-NODAGA-cLAB-TATEs
  12. Development of [99mTc]TcO-ABX474: Design, Synthesis, and Biological Evaluation of PSMA-Binding Technetium-99m Radioligands for SPECT Imaging of Prostate Cancer
  13. Carborane‐based Analogues of Celecoxib and Flurbiprofen, their COX Inhibition Potential and COX Selectivity Index
  14. Advances in Diclofenac Derivatives: Exploring Carborane‐Substituted N‐Methyl and Nitrile Analogs for Anti‐Cancer Therapy
  15. Exploring a Nitric Oxide-Releasing Celecoxib Derivative as a Potential Modulator of Bone Healing: Insights from Ex Vivo and In Vivo Imaging Experiments
  16. Front Cover: Carborane Conjugates with Ibuprofen, Fenoprofen and Flurbiprofen: Synthesis, Characterization, COX Inhibition Potential and In Vitro Activity (ChemMedChem 1/2025)
  17. Re-design and evaluation of diclofenac-based carborane-substituted prodrugs and their anti-cancer potential
  18. Towards more reliable experimental models for pancreatic cancer
  19. Cyclohexanediamine Triazole (CHDT) Functionalization Enables Labeling of Target Molecules with Al18F/68Ga/111In
  20. Programmable Release of Chemotherapeutics from Ferrocene‐Based Injectable Hydrogels Slows Melanoma Growth
  21. Carborane Conjugates with Ibuprofen, Fenoprofen and Flurbiprofen: Synthesis, Characterization, COX Inhibition Potential and In Vitro Activity
  22. Cover Feature: 64Cu tumor labeling with hexadentate picolinic acid‐based bispidine immunoconjugates (Chem. Eur. J. 32/2024)
  23. 64 Cu tumor labeling with hexadentate picolinic acid‐based bispidine immunoconjugates
  24. Impact of Viscosity on Human Hepatoma Spheroids in Soft Core–Shell Microcapsules
  25. Correction to: Radiosynthesis and biological evaluation of [18F]AG-120 for PET imaging of the mutant isocitrate dehydrogenase 1 in glioma
  26. Preclinical evaluation of an 18F-labeled Nε-acryloyllysine piperazide for covalent targeting of transglutaminase 2
  27. Improving susceptibility of neuroendocrine tumors to radionuclide therapies: personalized approaches towards complementary treatments
  28. Towards an advanced clinical use of radiocopper in cancer theranostics
  29. Radiosynthesis and biological evaluation of [18F]AG-120 for PET imaging of the mutant isocitrate dehydrogenase 1 in glioma
  30. Lysyl Oxidases as Targets for Cancer Therapy and Diagnostic Imaging
  31. Correction to Impedimetric Nanobiosensor for the Detection of SARS-CoV-2 Antigens and Antibodies
  32. Anti-Cancer Prodrug Cyclophosphamide Exerts Thrombogenic Effects on Human Venous Endothelial Cells Independent of CYP450 Activation—Relevance to Thrombosis
  33. Comparative Saturation Binding Analysis of 64Cu-Labeled Somatostatin Analogues Using Cell Homogenates and Intact Cells
  34. Synthesis and In Vitro Biological Evaluation of p-Carborane-Based Di-tert-butylphenol Analogs
  35. Outside Back Cover: (Biotechnology Journal 6/2023)
  36. Reactivating damaged motor neurons using magnetic fields
  37. Preclinical Characterization of the 177Lu-Labeled Prostate Stem Cell Antigen (PSCA)-Specific Monoclonal Antibody 7F5
  38. Isonimesulide and Its Carborane Analogues as Isoform‐Selective COX Inhibitors and Antitumor Agents
  39. Carborane‐based Tebufelone Analogs and their Biological Evaluation In Vitro
  40. Specific and safe targeting of glioblastoma using switchable and logic-gated RevCAR T cells
  41. Metastatic pheochromocytoma and paraganglioma: Somatostatin receptor 2 expression, genetics and therapeutic responses
  42. Shell engineering in soft alginate‐based capsules for culturing liver spheroids
  43. Dipeptide-Derived Alkynes as Potent and Selective Irreversible Inhibitors of Cysteine Cathepsins
  44. A self-assembled dynamic extracellular matrix-like hydrogel system with multi-scale structures for cell bioengineering applications
  45. Front Cover: Carborane Analogues of Fenoprofen Exhibit Improved Antitumor Activity (ChemMedChem 5/2023)
  46. Impedimetric Nanobiosensor for the Detection of SARS-CoV-2 Antigens and Antibodies
  47. Microdialysis Reveals Anti-Inflammatory Effects of Sulfated Glycosaminoglycanes in the Early Phase of Bone Healing
  48. Solid-Phase Parallel Synthesis of Dual Histone Deacetylase-Cyclooxygenase Inhibitors
  49. Prostaglandins and the Lung
  50. The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2
  51. Modulating the Renal Clearance of Targeted Radiopharmaceuticals
  52. Carborane-based Compounds in Dual Inhibitor Design
  53. Pheochromocytoma radionuclide theranostics and radiation transcriptomics
  54. Carborane Analogues of Fenoprofen Exhibit Improved Antitumor Activity
  55. Impact of Sulfated Hyaluronan on Bone Metabolism in Diabetic Charcot Neuroarthropathy and Degenerative Arthritis
  56. Toward Personalized Medicine: One Chelator for Imaging and Therapy with Lutetium-177 and Actinium-225
  57. Targeting neuropeptide receptors for cancer imaging
  58. New link between dietary phosphate and coronary heart disease
  59. NO• donors in cancer therapy
  60. Case report: Incidentally discovered case of pheochromocytoma as a cause of long COVID-19 syndrome
  61. Better understanding the metabolic stability of radiotracers
  62. Shell engineering in soft alginate-based capsules for culturing liver tumoroids
  63. Carboranyl Analogues of Mefenamic Acid and Their Biological Evaluation
  64. Application of a Fluorescence Anisotropy-Based Assay to Quantify Transglutaminase 2 Activity in Cell Lysates
  65. The Role of Transglutaminase 2 in the Radioresistance of Melanoma Cells
  66. Acceleration to the next level
  67. Personalized drug testing in human pheochromocytoma/paraganglioma primary cultures
  68. CRISPR/Cas9 Mediated Knockout of Cyclooxygenase-2 Gene Inhibits Invasiveness in A2058 Melanoma Cells
  69. A Self‐Assembled Matrix System for Cell‐Bioengineering Applications in Different Dimensions, Scales, and Geometries
  70. Targeting estrogen receptors in melanoma
  71. Targeting bone with copper radionuclides
  72. “Clickable” Albumin Binders for Modulating the Tumor Uptake of Targeted Radiopharmaceuticals
  73. Solid-Phase Synthesis of Selectively Mono-Fluorobenz(o)ylated Polyamines as a Basis for the Development of 18F-Labeled Radiotracers
  74. Hybrid agents for multimodal imaging
  75. Men who stare at bone: multimodal monitoring of bone healing
  76. Radiolabelled Cyclic Bisarylmercury: High Chemical and in vivo Stability for Theranostics
  77. Modulation of γ-Secretase Activity by a Carborane-Based Flurbiprofen Analogue
  78. Conductive Hydrogels with Dynamic Reversible Networks for Biomedical Applications
  79. Immunocompatibility and non-thrombogenicity of gelatin-based hydrogels
  80. Convergent synthesis of diversified reversible network leads to liquid metal-containing conductive hydrogel adhesives
  81. Development of an 18F-Labeled Irreversible Inhibitor of Transglutaminase 2 as Radiometric Tool for Quantitative Expression Profiling in Cells and Tissues
  82. Development of a ghrelin receptor inverse agonist for positron emission tomography
  83. The transCampus Metabolic Training Programme Explores the Link of SARS-CoV-2 Virus to Metabolic Disease
  84. Response of Endothelial Cells to Gelatin-Based Hydrogels
  85. Pseudohypoxia causes radioresistance
  86. Screening Arrays of Laminin Peptides on Modified Cellulose for Promotion of Adhesion of Primary Endothelial and Neural Precursor Cells
  87. A modular, injectable, non-covalently assembled hydrogel system features widescale tunable degradability for controlled release and tissue integration
  88. The Pyrazolo[3,4-d]pyrimidine-Based Kinase Inhibitor NVP-BHG712: Effects of Regioisomers on Tumor Growth, Perfusion, and Hypoxia in EphB4-Positive A375 Melanoma Xenografts
  89. The influence of different artificial extracellular matrix implant coatings on the regeneration of a critical size femur defect in rats
  90. Pseudohypoxia promotes metastasis
  91. Recent Insights in Barium-131 as a Diagnostic Match for Radium-223: Cyclotron Production, Separation, Radiolabeling, and Imaging
  92. Radiopharmaceutical Cancer Research goes 3D
  93. Metabolomics, machine learning and immunohistochemistry to predict succinate dehydrogenase mutational status in phaeochromocytomas and paragangliomas
  94. Fighting Cancer: Targeting the Eph Receptor Tyrosine Kinase Subfamily
  95. Comparison of manual and automated ventricle segmentation in the maternal immune stimulation rat model of schizophrenia
  96. The sigma-1 receptor: Potential role in the modulation of cellular radiation sensitivity
  97. Adjuvant Drug-Assisted Bone Healing: Advances and Challenges in Drug Delivery Approaches
  98. Carboranyl Derivatives of Rofecoxib with Cytostatic Activity against Human Melanoma and Colon Cancer Cells
  99. Regulation of bone regeneration
  100. Adjuvant drug-assisted bone healing: Part I – Modulation of inflammation
  101. Adjuvant drug-assisted bone healing: Part II – Modulation of angiogenesis
  102. Adjuvant drug-assisted bone healing: Part III – Further strategies for local and systemic modulation
  103. Synthesis, radiolabelling and initial biological characterisation of 18F-labelled xanthine derivatives for PET imaging of Eph receptors
  104. Deuteration versus ethylation – strategies to improve the metabolic fate of an 18F-labeled celecoxib derivative
  105. Fluorescent mouse pheochromocytoma spheroids expressing hypoxia-inducible factor 2 alpha: Morphologic and radiopharmacologic characterization
  106. Active Targeting of Dendritic Polyglycerols for Diagnostic Cancer Imaging
  107. Bone healing made visible
  108. Synthesis and Cyclooxygenase Inhibition of Sulfonamide-Substituted (Dihydro)Pyrrolo[3,2,1-hi]indoles and Their Potential Prodrugs
  109. Pheochromocytoma/Paraganglioma: A Guide for the Practicing Clinician
  110. Characterization of Tissue Transglutaminase as a Potential Biomarker for Tissue Response toward Biomaterials
  111. A theranostic PSMA ligand for PET imaging and retargeting of T cells expressing the universal chimeric antigen receptor UniCAR
  112. Radiochemical and radiopharmacological characterization of a 64 Cu-labeled α-MSH analog conjugated with different chelators
  113. Targeting Cyclooxygenase-2 in Pheochromocytoma and Paraganglioma: Focus on Genetic Background
  114. Cytocompatible, Injectable, and Electroconductive Soft Adhesives with Hybrid Covalent/Noncovalent Dynamic Network
  115. Instant kit preparation of 68Ga-radiopharmaceuticals via the hybrid chelator DATA: clinical translation of [68Ga]Ga-DATA-TOC
  116. Carboranyl Analogues of Ketoprofen with Cytostatic Activity against Human Melanoma and Colon Cancer Cell Lines
  117. Nitric Oxide-Releasing Selective Estrogen Receptor Modulators: A Bifunctional Approach to Improve the Therapeutic Index
  118. Synthesis and preliminary radiopharmacological characterisation of an 11 C-labelled azadipeptide nitrile as potential PET tracer for imaging of cysteine cathepsins
  119. Impact of Extrinsic and Intrinsic Hypoxia on Catecholamine Biosynthesis in Absence or Presence of Hif2α in Pheochromocytoma Cells
  120. Limited importance of EphrinA1–ligand, Src kinase, and focal adhesion kinase in EphA2-mediated regulation of metastasis in Mel-Juso and A375 human melanoma cells
  121. Regulation of A375 melanoma cell adhesion and migration by EphB4 and EphrinB2 – insights from co-culture experiments
  122. Cover Feature: Carboranyl Analogues of Celecoxib with Potent Cytostatic Activity against Human Melanoma and Colon Cancer Cell Lines (ChemMedChem 3/2019)
  123. Carboranyl Analogues of Celecoxib with Potent Cytostatic Activity against Human Melanoma and Colon Cancer Cell Lines
  124. Fluorine-18 Labeling of S100 Proteins for Small Animal Positron Emission Tomography
  125. One-Pot Cascade Synthesis of Pyrazole Based Isosteres of Valdecoxib by a [3+2] Cycloaddition Sequence and Evaluation of Their Cox Inhibitory Activity
  126. Strain-specific metastatic phenotypes in pheochromocytoma allograft mice
  127. Diverse effects of phospholipase A2 receptor expression on LNCaP and PC-3 prostate cancer cell growth in vitro and in vivo
  128. Synthesis, 18F-labelling and radiopharmacological characterisation of the C-terminal 30mer of Clostridium perfringens enterotoxin as a potential claudin-targeting peptide
  129. Development of a novel target module redirecting UniCAR T cells to Sialyl Tn-expressing tumor cells
  130. Exploring pitfalls of 64Cu-labeled EGFR-targeting peptide GE11 as a potential PET tracer
  131. Causative treatment of acid aspiration induced acute lung injury – Recent trends from animal experiments and critical perspective
  132. From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo
  133. Evaluation of Fluorine-18-Labeled α1(I)-N-Telopeptide Analogs as Substrate-Based Radiotracers for PET Imaging of Melanoma-Associated Lysyl Oxidase
  134. Synthesis, Characterization, and Initial Biological Evaluation of [99m Tc]Tc-Tricarbonyl-labeled DPA-α-MSH Peptide Derivatives for Potential Melanoma Imaging
  135. Nε-Acryloyllysine Piperazides as Irreversible Inhibitors of Transglutaminase 2: Synthesis, Structure–Activity Relationships, and Pharmacokinetic Profiling
  136. Bridging from Brain to Tumor Imaging: (S)-(−)- and (R)-(+)-[18F]Fluspidine for Investigation of Sigma-1 Receptors in Tumor-Bearing Mice
  137. Engrafting human regulatory T cells with a flexible modular chimeric antigen receptor technology
  138. Overexpression of Receptor Tyrosine Kinase EphB4 Triggers Tumor Growth and Hypoxia in A375 Melanoma Xenografts: Insights from Multitracer Small Animal Imaging Experiments
  139. Novel valdecoxib derivatives by ruthenium(ii)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes – synthesis and COX-2 inhibition activity
  140. Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells
  141. An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment
  142. Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells
  143. Preparation of a novel radiotracer targeting the EphB4 receptor via radiofluorination using spiro azetidinium salts as precursor
  144. Biological characterization of novel nitroimidazole-peptide conjugates in vitr o and in vivo
  145. Novel Tumor Pretargeting System Based on Complementaryl-Configured Oligonucleotides
  146. In Vivo Examination of an Injectable Hydrogel System Crosslinked by Peptide-Oligosaccharide Interaction in Immunocompetent Nude Mice
  147. Human Endothelial Cell Models in Biomaterial Research
  148. Retargeting of T lymphocytes to PSCA- or PSMA positive prostate cancer cells using the novel modular chimeric antigen receptor platform technology “UniCAR”
  149. Cryogel-supported stem cell factory for customized sustained release of bispecific antibodies for cancer immunotherapy
  150. A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform
  151. Surface charge and particle size determine the metabolic fate of dendritic polyglycerols
  152. The why and how of amino acid analytics in cancer diagnostics and therapy
  153. Technetium-99m based small molecule radiopharmaceuticals and radiotracers targeting inflammation and infection
  154. Development of a18F-labeled Diaryl-Substituted Dihydropyrrolo[3,2,1-hi]indole as Potential Probe for Functional Imaging of Cyclooxygenase-2 with PET
  155. S100 proteins and scavenger receptors: what's going on?
  156. Zwitterionic Polymer-Coated Ultrasmall Superparamagnetic Iron Oxide Nanoparticles with Low Protein Interaction and High Biocompatibility
  157. Extracellular S100A4 affects endothelial cell integrity and stimulates transmigration of A375 melanoma cells
  158. Corrigendum: Synthesis and Kinetic Characterisation of Water-Soluble Fluorogenic Acyl Donors for Transglutaminase 2
  159. Synthesis and Kinetic Characterisation of Water-Soluble Fluorogenic Acyl Donors for Transglutaminase 2
  160. Development of Antioxidant COX-2 Inhibitors as Radioprotective Agents for Radiation Therapy—A Hypothesis-Driven Review
  161. Interaction of extracellular S100A4 with RAGE prompts prometastatic activation of A375 melanoma cells
  162. 177Lu-labelled macrocyclic bisphosphonates for targeting bone metastasis in cancer treatment
  163. Protective effects of 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors on oxidative modification of human low density lipoproteins in vitro
  164. Controlled immobilization of His-tagged proteins for protein-ligand interaction experiments using Ni2+-NTA layer on glass surfaces
  165. Gelatin-based Hydrogel Degradation and Tissue Interactionin vivo: Insights from Multimodal Preclinical Imaging in Immunocompetent Nude Mice
  166. Multimodal Somatostatin Receptor Theranostics Using [64Cu]Cu-/[177Lu]Lu-DOTA-(Tyr3)octreotate and AN-238 in a Mouse Pheochromocytoma Model
  167. Radiopharmacological characterization of 64Cu-labeled α-MSH analogs for potential use in imaging of malignant melanoma
  168. 68Ga- und 177Lu-markierte Bisphosphonate als Knochenmetastasen-Theranostika
  169. Influence of irradiation on release of endothelial microparticles (EMP) in vitro
  170. Development of indazolylpyrimidine derivatives as high-affine EphB4 receptor ligands and potential PET radiotracers
  171. Novel (pyrazolyl)benzenesulfonamides with a nitric oxide-releasing moiety as selective cyclooxygenase-2 inhibitors
  172. Copper(II) Cyclam Complexes withN-­Propionic Acid Pendant Arms
  173. Effects of pulmonary acid aspiration on the regional pulmonary blood flow within the first hour after injury: An observational study in rats1
  174. 18F-Labeled 1,4-Dioxa-8-azaspiro[4.5]decane Derivative: Synthesis and Biological Evaluation of a σ1Receptor Radioligand with Low Lipophilicity as Potent Tumor Imaging Agent
  175. Cysteine cathepsins: their role in tumor progression and recent trends in the development of imaging probes
  176. Synthesis and Biodistribution Studies of 3 H- and 64 Cu-Labeled Dendritic Polyglycerol and Dendritic Polyglycerol Sulfate
  177. Diaryl-Substituted (Dihydro)pyrrolo[3,2,1-hi]indoles, a Class of Potent COX-2 Inhibitors with Tricyclic Core Structure
  178. Reduced pulmonary blood flow in regions of injury 2 hours after acid aspiration in rats
  179. Optical imaging of COX-2: Studies on an autofluorescent 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitor
  180. Cyclopeptides containing the DEKS motif as conformationally restricted collagen telopeptide analogues: synthesis and conformational analysis
  181. Novel indole-based sigma-2 receptor ligands: synthesis, structure–affinity relationship and antiproliferative activity
  182. Biocompatibility and inflammatory response in vitro and in vivo to gelatin-based biomaterials with tailorable elastic properties
  183. In Vivo Fluorescence Imaging and Urinary Monoamines as Surrogate Biomarkers of Disease Progression in a Mouse Model of Pheochromocytoma
  184. Radiofluorination and first radiopharmacological characterization of a SWLAY peptide-based ligand targeting EphA2
  185. Binding properties of radiolabeled cetuximab conjugates
  186. Bispidine Dioxotetraaza Macrocycles: A New Class of Bispidines for 64Cu PET Imaging
  187. Radiolabeled Cetuximab Conjugates for EGFR Targeted Cancer Diagnostics and Therapy
  188. Metastatic potential of B16-F10 melanoma cells is enhanced by extracellular S100A4 derived from RAW264.7 macrophages
  189. ChemInform Abstract: Tissue Transglutaminase: An Emerging Target for Therapy and Imaging
  190. Radiolabeled anti-EGFR-antibody improves local tumor control after external beam radiotherapy and offers theragnostic potential
  191. 2,3-Diaryl-substituted indole based COX-2 inhibitors as leads for imaging tracer development
  192. Organotypical vascular model for characterization of radioprotective compounds: Studies on antioxidant 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors
  193. Synthesis and radiopharmacological evaluation of 64Cu-labeled bombesin analogs featuring a bis(2-pyridylmethyl)-1,4,7-triazacyclononane chelator
  194. Tissue transglutaminase: An emerging target for therapy and imaging
  195. Pulmonary Blood Flow Increases in Damaged Regions Directly after Acid Aspiration in Rats
  196. Optimization of Pentadentate Bispidines as Bifunctional Chelators for64Cu Positron Emission Tomography (PET)
  197. Synthesis and Radiopharmacological Characterisation of a Fluorine-18-Labelled Azadipeptide Nitrile as a Potential PET Tracer for in vivo Imaging of Cysteine Cathepsins
  198. Radiolabeled COX-2 Inhibitors for Non-Invasive Visualization of COX-2 Expression and Activity — A Critical Update
  199. Anti-tumor effects of peptide analogs targeting neuropeptide hormone receptors on mouse pheochromocytoma cells
  200. An Efficient Bioorthogonal Strategy Using CuAAC Click Chemistry for Radiofluorinations of SNEW Peptides and the Role of Copper Depletion
  201. Experimental hypoxia does not influence gene expression and protein synthesis of Eph receptors and ephrin ligands in human melanoma cells in vitro
  202. 2-Carbaborane-3-phenyl-1H-indoles-Synthesis via McMurry Reaction and Cyclooxygenase (COX) Inhibition Activity
  203. Copper(ii) chemistry of the functionalized macrocycle cyclam tetrapropionic acid
  204. Visualization of cyclooxygenase-2 using a 2,3-diarylsubstituted indole-based inhibitor and confocal laser induced cryofluorescence microscopy at 20K in melanoma cells in vitro
  205. 18F-Labeled phosphopeptide-cell-penetrating peptide dimers with enhanced cell uptake properties in human cancer cells
  206. Protein and non-protein biomarkers in melanoma: a critical update
  207. Fluorine-18 Radiolabeling and Radiopharmacological Characterization of a Benzodioxolylpyrimidine-based Radiotracer Targeting the Receptor Tyrosine Kinase EphB4
  208. Radiosynthesis of a 18F-labeled 2,3-diarylsubstituted indole via McMurry coupling for functional characterization of cyclooxygenase-2 (COX-2) in vitro and in vivo
  209. Design, Evaluation, and Comparison of Ghrelin Receptor Agonists and Inverse Agonists as Suitable Radiotracers for PET Imaging
  210. Irradiation affects cellular properties and Eph receptor expression in human melanoma cells
  211. Site-selective radiolabeling of peptides by 18F-fluorobenzoylation with [18F]SFB in solution and on solid phase: a comparative study
  212. Cyclin-Dependent Kinases (Cdk) as Targets for Cancer Therapy and Imaging
  213. Specific Targeting of Hypoxic Tumor Tissue with Nitroimidazole-Peptide Conjugates
  214. Synthesis of an 18F-labeled cyclin-dependent kinase-2 inhibitor
  215. Automated radiosynthesis of the thiol-reactive labeling agent N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide ([18F]FBAM)
  216. Copper-mediated cross-linking of S100A4, but not of S100A2, results in proinflammatory effects in melanoma cells
  217. Phosphopeptides with improved cellular uptake properties as ligands for the polo-box domain of polo-like kinase 1
  218. ChemInform Abstract: Synthesis and Evaluation of 1,5‐Diaryl‐Substituted Tetrazoles (IV) as Novel Selective Cyclooxygenase‐2 (COX‐2) Inhibitors.
  219. A novel tetrabranched neurotensin(8–13) cyclam derivative: Synthesis, 64Cu-labeling and biological evaluation
  220. Synthesis, characterization and biological evaluation of [188Re(N)(cys∼)(PNP)]+/0 mixed-ligand complexes as prototypes for the development of 188Re(N)-based target-specific radiopharmaceuticals
  221. Synthesis and evaluation of 1,5-diaryl-substituted tetrazoles as novel selective cyclooxygenase-2 (COX-2) inhibitors
  222. Expression, purification and fluorine-18 radiolabeling of recombinant S100A4: a potential probe for molecular imaging of receptor for advanced glycation endproducts in vivo?
  223. S100 proteins in health and disease
  224. Modulation of Adrenal Aldosterone Release by Oxidative Modification of Low-Density Lipoprotein
  225. S100A2 in cancerogenesis: a friend or a foe?
  226. Cyclin-Dependent Kinase 4/6 (Cdk4/6) Inhibitors: Perspectives in Cancer Therapy and Imaging
  227. Synthesis of neurotensin(8–13)–phosphopeptide heterodimers via click chemistry
  228. Scavenger receptors are associated with cellular interactions of S100A12 in vitro and in vivo
  229. Improved multimodality imaging using alginate molding in xenograft tumor models
  230. Effects of posture on regional pulmonary blood flow in rats as measured by PET
  231. Radiosynthesis and radiopharmacological evaluation of cyclin-dependent kinase 4 (Cdk4) inhibitors
  232. Eph receptors and ephrins: bloody players
  233. Influence of irradiation on metabolism and metastatic potential of B16-F10 melanoma cells
  234. Validation of 99mTc-labeled “4+1” fatty acids for myocardial metabolism and flow imaging
  235. Validation of 99mTc-labeled “4+1” fatty acids for myocardial metabolism and flow imaging
  236. Radiosynthesis and radiopharmacological evaluation of [N-methyl-11C]Org 34850 as a glucocorticoid receptor (GR)-binding radiotracer
  237. Synthesis and cyclooxygenase inhibition of various (aryl-1,2,3-triazole-1-yl)-methanesulfonylphenyl derivatives
  238. Cell Cycle Regulating Kinase Cdk4 as a Potential Target for Tumor Cell Treatment and Tumor Imaging
  239. Erratum
  240. Fluorine-18 labeling of phosphopeptides: A potential approach for the evaluation of phosphopeptide metabolism in vivo
  241. Reduction of Arteriosclerotic Nanoplaque Formation and Size by n-3 Fatty Acids in Patients after Valvular Defect Operation
  242. Effects of pioglitazone and/or simvastatin on low density lipoprotein subfractions in non-diabetic patients with high cardiovascular risk: A sub-analysis from the PIOSTAT study
  243. Prediabetic and diabetic in vivo modification of circulating low-density lipoprotein attenuates its stimulatory effect on adrenal aldosterone and cortisol secretion
  244. Synthesis and evaluation in vitro and in vivo of a 11C-labeled cyclooxygenase-2 (COX-2) inhibitor
  245. Radiolabeled Glucocorticoids as Molecular Probes for Imaging Brain Glucocorticoid Receptors by Means of Positron Emission Tomography (PET)
  246. Synthesis and Application of [18F]FDG-Maleimidehexyloxime ([18F]FDG-MHO): A [18F]FDG-Based Prosthetic Group for the Chemoselective18F-Labeling of Peptides and Proteins†
  247. Human S100A12: a novel key player in inflammation?
  248. Systematic comparison of two novel, thiol-reactive prosthetic groups for 18F labeling of peptides and proteins with the acylation agent succinimidyl-4-[18F]fluorobenzoate ([18F]SFB)
  249. Expression, purification and fluorine-18 radiolabeling of recombinant S100 proteins—potential probes for molecular imaging of receptor for advanced glycation endproducts (RAGE) in vivo
  250. Glycoxidation of Low Density Lipoprotein in Impaired Glucose Tolerance: Implications for the Pathogenesis of Diabetic Vascular Disease
  251. Yttrium-86-labelled human serum albumin microspheres: relation of surface structure with in vivo stability
  252. Modified “4 + 1” Mixed Ligand Technetium-Labeled Fatty Acids for Myocardial Imaging: Evaluation of Myocardial Uptake and Biodistribution
  253. L-Type Amino Acid Transporters LAT1 and LAT4 in Cancer: Uptake of 3-O-Methyl-6- 18F-Fluoro-L-Dopa in Human Adenocarcinoma and Squamous Cell Carcinoma In Vitro and In Vivo
  254. Localized proton magnetic resonance spectroscopy of lipids in adipose tissue at high spatial resolution in mice in vivo
  255. Factors influencing the formation of small dense low-density lipoprotein particles in dependence on the presence of the metabolic syndrome and on the degree of glucose intolerance
  256. Experimental hypoxia is a potent stimulus for radiotracer uptake in vitro: Comparison of different tumor cells and primary endothelial cells
  257. Myocardial uptake and biodistribution of newly designed technetium-labelled fatty acid analogues
  258. Synthesis and radiopharmacological characterization of [11C]AL-438 as a nonsteroidal ligand for imaging brain glucocorticoid receptors
  259. Glycoxidised LDL isolated from subjects with impaired glucose tolerance increases CD36 and peroxisome proliferator–activator receptor γ gene expression in macrophages
  260. Labeling of low-density lipoproteins using the 18F-labeled thiol-reactive reagent N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide
  261. Lipid transfer protein activities in subjects with impaired glucose tolerance
  262. Synthesis and Biological Evaluation of a New Type of99mTechnetium-Labeled Fatty Acid for Myocardial Metabolism Imaging
  263. Biodistribution and catabolism of 18F-labeled N-ε-fructoselysine as a model of Amadori products
  264. Positron emission tomography in food sciences
  265. Glucose-Induced Enhancement of Hemin-Catalyzed LDL Oxidation In Vitro and In Vivo
  266. Small animal positron emission tomography in food sciences
  267. Catabolism of native and oxidized low density lipoproteins: in vivo insights from small animal positron emission tomography studies
  268. Synthesis and biodistribution of an 18F-labelled resveratrol derivative for small animal positron emission tomography
  269. Biodistribution and catabolism of 18F-labelled isopeptide Nɛ-(γ-glutamyl)-L-lysine
  270. Fluorine-18 radiolabeling of low-density lipoproteins: a potential approach for characterization and differentiation of metabolism of native and oxidized low-density lipoproteins in vivo
  271. Oxidativ modifizierte Lipoproteine und deren Antik�rper bei Patienten mit Antiphospholipidsyndrom und Systemischem Lupus erythematodes
  272. The pivotal role of scavenger receptor CD36 and phagocyte-derived oxidants in oxidized low density lipoprotein-induced adhesion to endothelial cells
  273. The protective effects of HDL and its constitutents against neutrophil respiratory burst activation by hypochlorite-oxidized LDL
  274. The effect of garlic on arteriosclerotic nanoplaque formation and size
  275. Analysis of non-protein amino acids as specific markers of low density lipoprotein apolipoprotein B-100 oxidation in human atherosclerotic lesions: the use ofN(O)-ethoxycarbonyl trifluoroethyl ester derivatives and GC-MS1
  276. Analysis of 6-hydroxy-2-aminocaproic acid (HACA) as a specific marker of protein oxidation: The use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and gas chromatography/mass spectrometry
  277. Measurement of 5-hydroxy-2-aminovaleric acid as a specific marker of metal catalysed oxidation of proline and arginine residues of low density lipoprotein apolipoprotein B-100 in human atherosclerotic lesions
  278. Lack of Association between Serum Paraoxonase 1 Activities and Increased Oxidized Low-Density Lipoprotein Levels in Impaired Glucose Tolerance and Newly Diagnosed Diabetes Mellitus
  279. Analysis of 3-chlorotyrosine as a specific marker of protein oxidation: the use ofN(O,S)-ethoxycarbonyltrifluoroethyl ester derivatives and gas chromatography/mass spectrometry
  280. Validation of different chemilumigenic substrates for detecting extracellular generation of reactive oxygen species by phagocytes and endothelial cells
  281. In Vivo Evidence for Increased Oxidation of Circulating LDL in Impaired Glucose Tolerance
  282. Protective Effects of Native But Not Oxidized High-Density Lipoprotein against Proinflammatory Respiratory Burst Activities of Polymorphonuclear Leukocytes Induced by Hypochlorite-Oxidized Low-Density Lipoprotein
  283. UVB-Induced Conversion of 7-Dehydrocholesterol to 1α,25-Dihydroxyvitamin D3 in an In Vitro Human Skin Equivalent Model
  284. Homocysteine levels in patients treated with lipid apheresis: effect of a vitamin therapy
  285. Different susceptibility to oxidation of proline and arginine residues of apolipoprotein B-100 among subspecies of low density lipoproteins
  286. Oxidation of Apolipoprotein B-100 in Circulating LDL Is Related to LDL Residence Time
  287. Impaired glucose tolerance (IGT) is not associated with disturbed homocysteine metabolism
  288. Conversion of vitamin D3 to 1alpha,25-dihydroxyvitamin D3 in human skin equivalents
  289. Measurement of 5-Hydroxy-2-aminovaleric Acid as a Specific Marker of Iron-Mediated Oxidation of Proline and Arginine Side-Chain Residues of Low-Density Lipoprotein Apolipoprotein B-100
  290. Urate modifies lipoprotein oxidation
  291. Human secretory group IIA phospholipase A2 is associated with lipid metabolism
  292. Störungen des Lipid- und Lipoproteinstoffwechsels
  293. Metabolic Basis of Low High Density Lipoprotein in Subjects with Impaired Glucose Tolerance
  294. Very Low Density Lipoprotein Overproduction Is Maximally Expressed in Early Insulin Resistant States
  295. In vivo evidence for increased apolipoprotein A-I catabolism in subjects with impaired glucose tolerance
  296. Human keratinocyte line HaCaT metabolizes 1α-hydroxyvitamin D3 and vitamin D3 to 1α,25-dihydroxyvitamin D3 (calcitriol)
  297. Determination of Total Homocysteine
  298. Hypochlorite-modified low-density lipoprotein stimulates human polymorphonuclear leukocytes for enhanced production of reactive oxygen metabolites, enzyme secretion, and adhesion to endothelial cells
  299. Stable isotope ratio analysis of amino acids: the use ofN(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and gas chromatography/mass spectrometry
  300. Stable isotope ratio analysis of amino acids: the use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and gas chromatography/mass spectrometry
  301. Rapid Determination of Total Homocysteine in Human Plasma by Using N(O,S)-Ethoxycarbonyl Ethyl Ester Derivatives and Gas Chromatography–Mass Spectrometry,
  302. Very fast ultracentrifugation of serum lipoproteins: influence on lipoprotein separation and composition
  303. Recovery of Cholesterol and Triacylglycerol in Very-Fast Ultracentrifugation of Human Lipoproteins in a Large Range of Concentrations
  304. Very-fast ultracentrifugation of human plasma lipoproteins: influence of the centrifugal field on lipoprotein composition