All Stories

  1. Decoding Plaque Instability Through Plasma Proteomics Profiling?

    Article • JACC Basic to Translational Science, September 2026, Elsevier

    Manuel Mayr

  2. Comparative Analysis of Data Processing Tools for Mass Spectrometry Proteomics in Cardiovascular Research

    Article • Journal of Proteome Research, July 2026, American Chemical Society (ACS)

    Manuel Mayr

  3. Consensus statement on mass spectrometry-based proteomic analysis of cardiac tissue

    Article • Nature Cardiovascular Research, May 2026, Springer Science + Business Media

    Manuel Mayr

  4. Proteomic insights into bi-atrial remodelling in persistent atrial fibrillation

    Article • Cardiovascular Research, May 2026, Oxford University Press (OUP)

    Manuel Mayr

  5. Deficiency of ZC3HC1 Modulates Vascular Smooth Muscle Cell Phenotype and Increases Neointima Formation

    Article • Arteriosclerosis Thrombosis and Vascular Biology, March 2026, Wolters Kluwer Health

    Manuel Mayr

  6. Clinical Proteomics in Cardiovascular Medicine: Current Capabilities, Limitations, and Future Directions

    Article • Atherosclerosis, January 2026, Elsevier

    Manuel Mayr

  7. Anti‐Malondialdehyde Low‐Density Lipoprotein Antibodies and Valvular Calcification: A Substudy of the SCOT‐HEART Trial

    Article • Journal of the American Heart Association, November 2025, Wolters Kluwer Health

    Manuel Mayr

  8. A genetic map of human metabolism across the allele frequency spectrum

    Article • Nature Genetics, October 2025, Springer Science + Business Media

    Manuel Mayr

  9. Precision medicine requires precision proteomics: Discordance between proteomic and clinical assays in UK Biobank

    Article • Cardiovascular Research, September 2025, Oxford University Press (OUP)

    Manuel Mayr

  10. Cardiac regeneration beyond stem cells: harnessing sarcomere dynamics and endogenous repair mechanisms

    Article • Cardiovascular Research, June 2025, Oxford University Press (OUP)

    Manuel Mayr

  11. Platelets and inflammation—insights from platelet non-coding RNA content and release in the Bruneck study and the PACMAN-AMI trial

    Article • Cardiovascular Research, June 2025, Oxford University Press (OUP)

    Manuel Mayr

  12. ECM Modifications Driven by Age and Metabolic Stress Directly Promote Vascular Smooth Muscle Cell Osteogenic Processes

    Article • Arteriosclerosis Thrombosis and Vascular Biology, March 2025, Wolters Kluwer Health

    Manuel Mayr

  13. Transcriptional Atlas of Cardiac Disease

    Article • February 2025, Springer Science + Business Media

    Manuel Mayr

  14. A genetic map of human metabolism across the allele frequency spectrum

    Article • February 2025, Cold Spring Harbor Laboratory Press

    Manuel Mayr

  15. Cervical Artery Tortuosity Is Associated With Dissection Occurrence and Late Recurrence: A Nested Case-Control Study

    Article • Stroke, February 2025, Wolters Kluwer Health

    Manuel Mayr

  16. Dissecting the effect of genetic variants on atherosclerosis: integrating bulk and single-cell transcriptomics

    Article • European Heart Journal, November 2024, Oxford University Press (OUP)

    Manuel Mayr

  17. Differential effects of physiological agonists on the proteome of platelet‐derived extracellular vesicles

    Article • PROTEOMICS, August 2024, Wiley

    Manuel Mayr

  18. Longitudinal Lipidomic Signature of Coronary Heart Disease in American Indian People

    Article • Journal of the American Heart Association, February 2024, Wolters Kluwer Health

    Manuel Mayr

  19. Enhancing cardiovascular risk prediction through proteomics?

    Article • Cardiovascular Research, February 2024, Oxford University Press (OUP)

    Manuel Mayr

  20. Inhibition of miR-199a-3p in a murine hypertrophic cardiomyopathy (HCM) model attenuates fibrotic remodeling

    Article • Journal of Molecular and Cellular Cardiology Plus, December 2023, Elsevier

    Manuel Mayr

  21. Phenylalanine-tRNA aminoacylation is compromised by ALS/FTD-associated C9orf72 C4G2 repeat RNA

    Article • Nature Communications, September 2023, Springer Science + Business Media

    Manuel Mayr

  22. Proteomic Atlas of Atherosclerosis: The Contribution of Proteoglycans to Sex Differences, Plaque Phenotypes, and Outcomes

    Article • Circulation Research, September 2023, Wolters Kluwer Health

    Manuel Mayr

  23. Human blood vessel organoids reveal a critical role for CTGF in maintaining microvascular integrity

    Article • Nature Communications, September 2023, Springer Science + Business Media

    Manuel Mayr

  24. Effect of Alirocumab Added to High-Intensity Statin on Platelet Reactivity and Noncoding RNAs in Patients with AMI: A Substudy of the PACMAN-AMI Trial

    Article • Thrombosis and Haemostasis, August 2023, Thieme Publishing Group

    Manuel Mayr

  25. SERCA2a Protein Levels Are Unaltered in Human Heart Failure

    Article • Circulation, August 2023, Wolters Kluwer Health

    Manuel Mayr

  26. Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein

    Article • Molecular & Cellular Proteomics, August 2023, Elsevier

    Manuel Mayr

  27. Uncovering Protein Networks in Cardiovascular Proteomics

    Article • Molecular & Cellular Proteomics, August 2023, Elsevier

    Manuel Mayr

  28. Reducing reductionism: addressing risk for atherosclerotic cardiovascular disease by apolipoprotein proteomics

    Article • European Heart Journal, June 2023, Oxford University Press (OUP)

    Manuel Mayr

  29. Proteomics and lipidomics in atherosclerotic cardiovascular disease risk prediction

    Article • European Heart Journal, March 2023, Oxford University Press (OUP)

    Manuel Mayr

  30. Desmosomal protein degradation as an underlying cause of arrhythmogenic cardiomyopathy

    Article • Science Translational Medicine, March 2023, American Association for the Advancement of Science

    Manuel Mayr

  31. Apolipoprotein Proteomics for Residual Lipid-Related Risk in Coronary Heart Disease

    Article • Circulation Research, February 2023, Wolters Kluwer Health

    Manuel Mayr

  32. CNP Promotes Antiarrhythmic Effects via Phosphodiesterase 2

    Article • Circulation Research, February 2023, Wolters Kluwer Health

    Manuel Mayr

  33. Letter by Gutmann et al Regarding Article, “Circulating MicroRNA-122-5p Is Associated With a Lack of Improvement in Left Ventricular Function After Transcatheter Aortic Valve Replacement and Regulates Viability of Cardiomyocytes Through Extracellular V...

    Article • Circulation, January 2023, Wolters Kluwer Health

    Manuel Mayr

  34. Extracellular Matrix Profiling and Disease Modelling in Engineered Vascular Smooth Muscle Cell Tissues

    Article • Matrix Biology Plus, December 2022, Elsevier

    Manuel Mayr

  35. Temporal in vivo platelet labeling in mice reveals age-dependent receptor expression and conservation of specific mRNAs

    Article • Blood Advances, November 2022, American Society of Hematology

    Manuel Mayr

  36. Reduced secretion of neuronal growth regulator 1 contributes to impaired adipose-neuronal crosstalk in obesity

    Article • Nature Communications, November 2022, Springer Science + Business Media

    Manuel Mayr

  37. Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization

    Article • Aging Cell, November 2022, Wiley

    Manuel Mayr, Professor David Middleton

  38. SGLT2 inhibitors in heart failure: insights from plasma proteomics

    Article • European Heart Journal, November 2022, Oxford University Press (OUP)

    Manuel Mayr

  39. Phenylalanine-tRNA aminoacylation is compromised by ALS/FTD-associated C9orf72 C4G2 repeat RNA

    Article • November 2022, Research Square

    Manuel Mayr

  40. Integrative single-cell meta-analysis reveals disease-relevant vascular cell states and markers in human atherosclerosis

    Article • October 2022, Cold Spring Harbor Laboratory Press

    Manuel Mayr

  41. SGLT2 Inhibitors in Heart Failure: Targeted Metabolomics and Energetic Metabolism

    Article • Circulation, September 2022, Wolters Kluwer Health

    Manuel Mayr

  42. Human blood vessel organoids reveal a critical role for CTGF in maintaining microvascular integrity

    Article • September 2022, Cold Spring Harbor Laboratory Press

    Manuel Mayr

  43. Serial measurements of protein and microRNA biomarkers to specify myocardial infarction subtypes

    Article • Journal of Molecular and Cellular Cardiology Plus, September 2022, Elsevier

    Manuel Mayr

  44. Effect of Alirocumab Added to High-Intensity Statin Therapy on Coronary Atherosclerosis in Patients With Acute Myocardial Infarction

    Article • JAMA, May 2022, American Medical Association (AMA)

    Manuel Mayr

  45. Precision Medicine Approach for Cardiometabolic Risk Factors in Therapeutic Apheresis

    Article • Hormone and Metabolic Research, April 2022, Thieme Publishing Group

    Manuel Mayr

  46. Correction: Precision Medicine Approach for Cardiometabolic Risk Factors in Therapeutic Apheresis

    Article • Hormone and Metabolic Research, April 2022, Thieme Publishing Group

    Manuel Mayr

  47. Methods for the identification and characterization of extracellular vesicles in cardiovascular studies: from exosomes to microvesicles

    Article • Cardiovascular Research, March 2022, Oxford University Press (OUP)

    Prof. Lucio Barile, Manuel Mayr

  48. Circulating microRNAs as biomarkers and mediators of platelet activation

    Article • Platelets, March 2022, Taylor & Francis

    Manuel Mayr

  49. Sexual dimorphism in COVID-19: potential clinical and public health implications

    Article • The Lancet Diabetes & Endocrinology, March 2022, Elsevier

    Manuel Mayr

  50. Linking Genetics and Proteomics: Gene-Protein Associations Built on Diversity

    Article • Circulation, February 2022, Wolters Kluwer Health

    Manuel Mayr

  51. Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

    Article • Cardiovascular Research, January 2022, Oxford University Press (OUP)

    Manuel Mayr

  52. Association of adolescent lipoprotein subclass profile with carotid intima-media thickness and comparison to adults: Prospective population-based cohort studies

    Article • Atherosclerosis, January 2022, Elsevier

    Manuel Mayr

  53. Isolation of Circulating Extracellular Vesicles by High-Performance Size-Exclusion Chromatography

    Article • January 2022, Springer Science + Business Media

    Manuel Mayr

  54. Neutrophil-Derived Protein S100A8/A9 Alters the Platelet Proteome in Acute Myocardial Infarction and Is Associated With Changes in Platelet Reactivity

    Article • Arteriosclerosis Thrombosis and Vascular Biology, January 2022, Wolters Kluwer Health

    Manuel Mayr

  55. Extracellular Matrix in Heart Failure: Role of ADAMTS5 in Proteoglycan Remodeling

    Article • Circulation, December 2021, Wolters Kluwer Health

    Manuel Mayr

  56. Temporal in vivo platelet labelling in mice reveals age-dependent receptor expression and conservation of specific mRNAs

    Article • December 2021, Cold Spring Harbor Laboratory Press

    Manuel Mayr

  57. Proteome and functional decline as platelets age in the circulation

    Article • Journal of Thrombosis and Haemostasis, December 2021, Elsevier

    Manuel Mayr

  58. PCSK9 Activity Is Potentiated Through HDL Binding

    Article • Circulation Research, November 2021, Wolters Kluwer Health

    Manuel Mayr

  59. Association of cardiometabolic microRNAs with COVID-19 severity and mortality

    Article • Cardiovascular Research, November 2021, Oxford University Press (OUP)

    Manuel Mayr

  60. Protein Aggregation Is an Early Manifestation of Phospholamban p.(Arg14del)–Related Cardiomyopathy: Development of PLN-R14del–Related Cardiomyopathy

    Article • Circulation Heart Failure, November 2021, Wolters Kluwer Health

    Manuel Mayr

  61. Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation

    Article • Circulation Research, October 2021, Wolters Kluwer Health

    Manuel Mayr

  62. Endothelial cells exposed to atheroprotective flow secrete follistatin-like 1 protein which reduces transcytosis and inflammation

    Article • Atherosclerosis, September 2021, Elsevier

    Manuel Mayr

  63. DRP1: a novel regulator of PCSK9 secretion and degradation

    Article • Cardiovascular Research, July 2021, Oxford University Press (OUP)

    Manuel Mayr

  64. Lessons from the spatiotemporal expression patterns of RNA vs. proteins during the cell cycle

    Article • Cardiovascular Research, June 2021, Oxford University Press (OUP)

    Manuel Mayr

  65. SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care

    Article • Nature Communications, June 2021, Springer Science + Business Media

    Manuel Mayr

  66. Proteome and functional decline as platelets age in the circulation

    Article • June 2021, Cold Spring Harbor Laboratory Press

    Manuel Mayr

  67. Lipoprotein compartmentalisation as a regulator of PCSK9 activity

    Article • Journal of Molecular and Cellular Cardiology, June 2021, Elsevier

    Manuel Mayr

  68. The Landscape of Coding and Noncoding RNAs in Platelets

    Article • Antioxidants & Redox Signaling, May 2021, Mary Ann Liebert Inc

    Manuel Mayr

  69. Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation

    Article • EMBO Molecular Medicine, May 2021, EMBO

    Manuel Mayr

  70. Fibroblast GATA-4 and GATA-6 promote myocardial adaptation to pressure overload by enhancing cardiac angiogenesis

    Article • Basic Research in Cardiology, April 2021, Springer Science + Business Media

    Manuel Mayr

  71. The transCampus Metabolic Training Programme Explores the Link of SARS-CoV-2 Virus to Metabolic Disease

    Article • Hormone and Metabolic Research, March 2021, Thieme Publishing Group

    Prof. Dr. Jens Pietzsch, Manuel Mayr, Professor Fiona M Watt

  72. Fibroblast Nox2 (NADPH Oxidase-2) Regulates ANG II (Angiotensin II)–Induced Vascular Remodeling and Hypertension via Paracrine Signaling to Vascular Smooth Muscle Cells

    Article • Arteriosclerosis Thrombosis and Vascular Biology, February 2021, Wolters Kluwer Health

    Manuel Mayr

  73. Loss of hepatic miR-33 improves metabolic homeostasis and liver function without altering body weight or atherosclerosis

    Article • Proceedings of the National Academy of Sciences, January 2021, Proceedings of the National Academy of Sciences

    Manuel Mayr

  74. A Proteomics-Based Assessment of Inflammation Signatures in Endotoxemia

    Article • Molecular & Cellular Proteomics, January 2021, Elsevier

    Manuel Mayr

  75. Systems biology in cardiovascular disease: a multiomics approach

    Article • Nature Reviews Cardiology, December 2020, Springer Science + Business Media

    Manuel Mayr

  76. SARS-CoV-2 RNAemia and proteomic biomarker trajectory inform prognostication in COVID-19 patients admitted to intensive care

    Article • November 2020, Research Square

    Manuel Mayr

  77. Proteomic landscape of TGF-β1-induced fibrogenesis in renal fibroblasts

    Article • Scientific Reports, November 2020, Springer Science + Business Media

    Manuel Mayr

  78. Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia

    Article • Nature, November 2020, Springer Science + Business Media

    Manuel Mayr

  79. Metabolic recovery after weight loss surgery is reflected in serum microRNAs

    Article • BMJ Open Diabetes Research & Care, October 2020, BMJ

    Manuel Mayr

  80. Extracellular matrix protein signature of recurrent spontaneous cervical artery dissection

    Article • Neurology, September 2020, Wolters Kluwer Health

    Manuel Mayr

  81. Cathepsin A contributes to left ventricular remodeling by degrading extracellular superoxide dismutase in mice

    Article • Journal of Biological Chemistry, September 2020, Elsevier

    Manuel Mayr

  82. Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement

    Article • Journal of the American Heart Association, August 2020, Wolters Kluwer Health

    Manuel Mayr

  83. Platelet “-omics” in health and cardiovascular disease

    Article • Atherosclerosis, August 2020, Elsevier

    Manuel Mayr

  84. Very preterm birth results in later lower platelet activation markers

    Article • Pediatric Research, July 2020, Springer Science + Business Media

    Manuel Mayr

  85. Cardiac dysfunction in cancer patients: beyond direct cardiomyocyte damage of anticancer drugs: novel cardio-oncology insights from the joint 2019 meeting of the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart

    Article • Cardiovascular Research, July 2020, Oxford University Press (OUP)

    Manuel Mayr

  86. Platelet Reactivity in Individuals Over 65 Years Old Is Not Modulated by Age

    Article • Circulation Research, July 2020, Wolters Kluwer Health

    Manuel Mayr

  87. Noncoding RNAs versus Protein Biomarkers in Cardiovascular Disease

    Article • Trends in Molecular Medicine, June 2020, Elsevier

    Manuel Mayr

  88. microRNAs as Promising Biomarkers of Platelet Activity in Antiplatelet Therapy Monitoring

    Article • International Journal of Molecular Sciences, May 2020, MDPI AG

    Manuel Mayr

  89. Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function

    Article • Cardiovascular Research, May 2020, Oxford University Press (OUP)

    Manuel Mayr

  90. Extracellular Matrix in Vascular Disease, Part 2/4

    Article • Journal of the American College of Cardiology, May 2020, Elsevier

    Manuel Mayr

  91. Circulating MicroRNA Levels Indicate Platelet and Leukocyte Activation in Endotoxemia Despite Platelet P2Y12 Inhibition

    Article • International Journal of Molecular Sciences, April 2020, MDPI AG

    Manuel Mayr

  92. Pkm2 Regulates Cardiomyocyte Cell Cycle and Promotes Cardiac Regeneration

    Article • Circulation, April 2020, Wolters Kluwer Health

    Manuel Mayr

  93. The ‘Digital Twin’ to enable the vision of precision cardiology

    Article • European Heart Journal, March 2020, Oxford University Press (OUP)

    Manuel Mayr

  94. Liver-specific microRNA-122 as prognostic biomarker in patients with chronic systolic heart failure

    Article • International Journal of Cardiology, March 2020, Elsevier

    Manuel Mayr

  95. High-Density Lipoproteins Are the Main Carriers of PCSK9 in the Circulation

    Article • Journal of the American College of Cardiology, March 2020, Elsevier

    Manuel Mayr

  96. FURIN Expression in Vascular Endothelial Cells Is Modulated by a Coronary Artery Disease–Associated Genetic Variant and Influences Monocyte Transendothelial Migration

    Article • Journal of the American Heart Association, February 2020, Wolters Kluwer Health

    Manuel Mayr

  97. ApoCIII-Lp(a) complexes in conjunction with Lp(a)-OxPL predict rapid progression of aortic stenosis

    Article • Heart, February 2020, BMJ

    Manuel Mayr

  98. Preclinical development of a miR-132 inhibitor for heart failure treatment

    Article • Nature Communications, January 2020, Springer Science + Business Media

    Manuel Mayr

  99. Aspirin, clopidogrel and prasugrel monotherapy in patients with type 2 diabetes mellitus: a double-blind randomised controlled trial of the effects on thrombotic markers and microRNA levels

    Article • Cardiovascular Diabetology, January 2020, Springer Science + Business Media

    Manuel Mayr

  100. Cartilage-like composition of keloid scar extracellular matrix suggests fibroblast mis-differentiation in disease

    Article • Matrix Biology Plus, November 2019, Elsevier

    Manuel Mayr

  101. Glycoproteomic Analysis of the Aortic Extracellular Matrix in Marfan Patients

    Article • Arteriosclerosis Thrombosis and Vascular Biology, September 2019, Wolters Kluwer Health

    Manuel Mayr

  102. TIP 30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation

    Article • EMBO Molecular Medicine, August 2019, EMBO

    Manuel Mayr

  103. A Plasma Proteogenomic Signature for Fibromuscular Dysplasia

    Article • Cardiovascular Research, August 2019, Oxford University Press (OUP)

    Manuel Mayr

  104. Response by Schulte et al to Letter Regarding Article, “Comparative Analysis of Circulating Noncoding RNAs Versus Protein Biomarkers in the Detection of Myocardial Injury”

    Article • Circulation Research, August 2019, Wolters Kluwer Health

    Manuel Mayr

  105. Comparative Analysis of Circulating Noncoding RNAs Versus Protein Biomarkers in the Detection of Myocardial Injury

    Article • Circulation Research, July 2019, Wolters Kluwer Health

    Manuel Mayr

  106. Apolipoprotein Profiles in Very Preterm and Term‐Born Preschool Children

    Article • Journal of the American Heart Association, April 2019, Wolters Kluwer Health

    Manuel Mayr

  107. Optogenetic Monitoring of the Glutathione Redox State in Engineered Human Myocardium

    Article • Frontiers in Physiology, April 2019, Frontiers

    Manuel Mayr

  108. Locally different proteome in aortas from patients with stenotic tricuspid and bicuspid aortic valves†

    Article • European Journal of Cardio-Thoracic Surgery, February 2019, Oxford University Press (OUP)

    Manuel Mayr

  109. Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology

    Article • European Journal of Heart Failure, February 2019, Wiley

    Professor John GF Cleland, Manuel Mayr

  110. MicroRNAs: A New Understanding of Platelet Physiology and Pathology

    Article • Thrombosis and Haemostasis, January 2019, Thieme Publishing Group

    Manuel Mayr

  111. The Emerging Role of the ADAMTS Family in Vascular Diseases

    Article • Circulation Research, December 2018, Wolters Kluwer Health

    Manuel Mayr

  112. In Aptamers They Trust

    Article • Circulation, November 2018, Wolters Kluwer Health

    Manuel Mayr

  113. Inhibition of profibrotic microRNA-21 affects platelets and their releasate

    Article • JCI Insight, November 2018, American Society for Clinical Investigation

    Manuel Mayr

  114. Hypoxia-induced epigenetic silencing of polo-like kinase 2 promotes fibrosis in atrial fibrillation

    Article • October 2018, Cold Spring Harbor Laboratory Press

    Manuel Mayr

  115. Characterisation of circulating biomarkers before and after cardiac resynchronisation therapy and their role in predicting CRT response: the COVERT-HF study

    Article • Open Heart, October 2018, BMJ

    Alan M Nevill, Manuel Mayr

  116. Higher spermidine intake is linked to lower mortality: a prospective population-based study

    Article • American Journal of Clinical Nutrition, August 2018, Elsevier

    Manuel Mayr

  117. Role of ADAMTS-5 in Aortic Dilatation and Extracellular Matrix Remodeling

    Article • Arteriosclerosis Thrombosis and Vascular Biology, July 2018, Wolters Kluwer Health

    Manuel Mayr

  118. Extracellular Vesicle Crosstalk Between the Myocardium and Immune System Upon Infarction

    Article • Circulation Research, June 2018, Wolters Kluwer Health

    Manuel Mayr

  119. Metabolic changes in hypertrophic cardiomyopathies: scientific update from the Working Group of Myocardial Function of the European Society of Cardiology

    Article • Cardiovascular Research, June 2018, Oxford University Press (OUP)

    Manuel Mayr

  120. Expanding the horizons of microRNA bioinformatics

    Article • RNA, June 2018, Cold Spring Harbor Laboratory Press

    Manuel Mayr

  121. MicroRNA-24 and the Diabetic Heart

    Article • JACC Basic to Translational Science, June 2018, Elsevier

    Manuel Mayr

  122. Non-coding RNAs in vascular disease – from basic science to clinical applications: scientific update from the Working Group of Myocardial Function of the European Society of Cardiology

    Article • Cardiovascular Research, May 2018, Oxford University Press (OUP)

    Manuel Mayr

  123. MicroRNA-21 and the Vulnerability of Atherosclerotic Plaques

    Article • Molecular Therapy, April 2018, Elsevier

    Manuel Mayr

  124. Downregulation of MicroRNA-126 Augments DNA Damage Response in Cigarette Smokers and Patients with Chronic Obstructive Pulmonary Disease

    Article • American Review of Respiratory Disease, March 2018, American Thoracic Society

    Dr Koralia Paschalaki, Manuel Mayr

  125. Correction: Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease

    Article • Journal of Experimental Medicine, February 2018, Rockefeller University Press

    Manuel Mayr

  126. Cardiovascular Risk Beyond Low-Density Lipoprotein Cholesterol

    Article • Journal of the American College of Cardiology, February 2018, Elsevier

    Manuel Mayr

  127. The innate immune system in chronic cardiomyopathy: a European Society of Cardiology (ESC) scientific statement from the Working Group on Myocardial Function of the ESC

    Article • European Journal of Heart Failure, January 2018, Wiley

    Manuel Mayr

  128. Extracellular Matrix Proteomics Reveals Interplay of Aggrecan and Aggrecanases in Vascular Remodeling of Stented Coronary Arteries

    Article • Circulation, January 2018, Wolters Kluwer Health

    Dr Stephen White, Manuel Mayr

  129. Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation

    Article • JCI Insight, December 2017, American Society for Clinical Investigation

    Manuel Mayr

  130. Comparison of MOLLI, shMOLLLI, and SASHA in discrimination between health and disease and relationship with histologically derived collagen volume fraction

    Article • European Heart Journal - Cardiovascular Imaging, December 2017, Oxford University Press (OUP)

    Manuel Mayr

  131. Plasma Proteomics for Epidemiology

    Article • Circulation Cardiovascular Genetics, December 2017, Wolters Kluwer Health

    Manuel Mayr

  132. Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling

    Article • Nature Communications, November 2017, Springer Science + Business Media

    Manuel Mayr

  133. An integrative translational approach to study heart failure with preserved ejection fraction: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology

    Article • European Journal of Heart Failure, November 2017, Wiley

    Manuel Mayr

  134. Genetic Dissection of the Impact of miR-33a and miR-33b during the Progression of Atherosclerosis

    Article • Cell Reports, October 2017, Elsevier

    Manuel Mayr

  135. Very low-density lipoprotein associated apolipoproteins predict cardiovascular events and are lowered by inhibition of apoC-III

    Article • Atherosclerosis Supplements, September 2017, Elsevier

    Manuel Mayr

  136. CRISPR/Cas9 editing reveals novel mechanisms of clustered microRNA regulation and function

    Article • Scientific Reports, August 2017, Springer Science + Business Media

    Manuel Mayr

  137. What are the prospects of apolipoprotein profiling for cardiovascular disease?

    Article • Expert Review of Molecular Diagnostics, July 2017, Taylor & Francis

    Manuel Mayr

  138. Cardiac myocyte β3-adrenergic receptors prevent myocardial fibrosis by modulating oxidant stress-dependent paracrine signaling

    Article • European Heart Journal, July 2017, Oxford University Press (OUP)

    Manuel Mayr

  139. Long Noncoding RNAs and Angiogenesis

    Article • Circulation, July 2017, Wolters Kluwer Health

    Manuel Mayr

  140. Proteomics of the epicardial fat secretome and its role in post-operative atrial fibrillation

    Article • EP Europace, June 2017, Oxford University Press (OUP)

    Manuel Mayr

  141. 195 Crispr/cas9 gene editing reveals novel tertiary constraints in clustered mirna processing

    Article • Heart, June 2017, BMJ

    Manuel Mayr

  142. Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease

    Article • Journal of Experimental Medicine, May 2017, Rockefeller University Press

    Manuel Mayr

  143. Association Between Vascular Cell Adhesion Molecule 1 and Atrial Fibrillation

    Article • JAMA Cardiology, May 2017, American Medical Association (AMA)

    Manuel Mayr

  144. Epigenomic and transcriptomic approaches in the post-genomic era: path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart

    Article • Cardiovascular Research, April 2017, Oxford University Press (OUP)

    Manuel Mayr

  145. Mitochondria and ageing: role in heart, skeletal muscle and adipose tissue

    Article • Journal of Cachexia Sarcopenia and Muscle, April 2017, Wiley

    Manuel Mayr

  146. Glycoproteomics of the Extracellular Matrix: A Method for Intact Glycopeptide Analysis Using Mass Spectrometry

    Article • Journal of Visualized Experiments, April 2017, MyJove Corporation

    Manuel Mayr

  147. Reply

    Article • Journal of the American College of Cardiology, April 2017, Elsevier

    Manuel Mayr

  148. Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques

    Article • Journal of Clinical Investigation, March 2017, American Society for Clinical Investigation

    Manuel Mayr

  149. High-density lipoproteins in high resolution: Will proteomics solve the paradox for cardiovascular risk?

    Article • PROTEOMICS, February 2017, Wiley

    Manuel Mayr

  150. Very-Low-Density Lipoprotein–Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III

    Article • Journal of the American College of Cardiology, February 2017, Elsevier

    Manuel Mayr

  151. MicroRNA Biomarkers and Platelet Reactivity

    Article • Circulation Research, January 2017, Wolters Kluwer Health

    Manuel Mayr

  152. Premature senescence of endothelial cells upon chronic exposure to TNFα can be prevented by N-acetyl cysteine and plumericin

    Article • Scientific Reports, January 2017, Springer Science + Business Media

    Manuel Mayr

  153. Diabetes Mellitus–Induced Microvascular Destabilization in the Myocardium

    Article • Journal of the American College of Cardiology, January 2017, Elsevier

    Manuel Mayr

  154. MicroRNAs in Cardiovascular Disease

    Article • Journal of the American College of Cardiology, December 2016, Elsevier

    Manuel Mayr

  155. Circulating MicroRNA-122 Is Associated With the Risk of New-Onset Metabolic Syndrome and Type 2 Diabetes

    Article • Diabetes, November 2016, American Diabetes Association

    Manuel Mayr

  156. Potential and Caveats of Lipidomics for Cardiovascular Disease

    Article • Circulation, November 2016, Wolters Kluwer Health

    Manuel Mayr

  157. Cardioprotection and lifespan extension by the natural polyamine spermidine

    Article • Nature Medicine, November 2016, Springer Science + Business Media

    Professor Luca Scorrano, Manuel Mayr

  158. Native T1 and T2 mapping by CMR in lupus myocarditis: Disease recognition and response to treatment

    Article • International Journal of Cardiology, November 2016, Elsevier

    Manuel Mayr

  159. From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on “New frontiers in cardiovascular research”

    Article • Basic Research in Cardiology, October 2016, Springer Science + Business Media

    Dr. Hector Cabrera-Fuentes, Dr Heeraj Bulluck, Manuel Mayr

  160. Systems biology—opportunities and challenges: the application of proteomics to study the cardiovascular extracellular matrix

    Article • Cardiovascular Research, September 2016, European Society of Cardiology

    Manuel Mayr

  161. Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation

    Article • Circulation, September 2016, Wolters Kluwer Health

    Manuel Mayr

  162. Caveats of Untargeted Metabolomics for Biomarker Discovery ∗

    Article • Journal of the American College of Cardiology, September 2016, Elsevier

    Manuel Mayr

  163. Identification of cyclins A1, E1 and vimentin as downstream targets of heme oxygenase-1 in vascular endothelial growth factor-mediated angiogenesis

    Article • Scientific Reports, July 2016, Springer Science + Business Media

    Manuel Mayr

  164. Proteomic and metabolomic changes driven by elevating myocardial creatine suggest novel metabolic feedback mechanisms

    Article • Amino Acids, May 2016, Springer Science + Business Media

    Manuel Mayr

  165. Chronic miR‐29 antagonism promotes favorable plaque remodeling in atherosclerotic mice

    Article • EMBO Molecular Medicine, May 2016, EMBO

    Manuel Mayr

  166. Loss of Biglycan Enhances Thrombin Generation in Apolipoprotein E -Deficient Mice

    Article • Arteriosclerosis Thrombosis and Vascular Biology, May 2016, Wolters Kluwer Health

    Manuel Mayr

  167. Oxidant-induced Interprotein Disulfide Formation in Cardiac Protein DJ-1 Occurs via an Interaction with Peroxiredoxin 2

    Article • Journal of Biological Chemistry, May 2016, Elsevier

    Manuel Mayr

  168. Liver microRNAs: potential mediators and biomarkers for metabolic and cardiovascular disease?

    Article • European Heart Journal, April 2016, European Society of Cardiology

    Manuel Mayr

  169. Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

    Article • Cardiovascular Research, April 2016, European Society of Cardiology

    Manuel Mayr

  170. Pharmacogenetics of Clopidogrel

    Article • Circulation Cardiovascular Genetics, April 2016, Wolters Kluwer Health

    Manuel Mayr

  171. Vascular proteomics in metabolic and cardiovascular diseases

    Article • Journal of Internal Medicine, March 2016, Wiley

    Manuel Mayr

  172. “Young at heart”: Regenerative potential linked to immature cardiac phenotypes

    Article • Journal of Molecular and Cellular Cardiology, March 2016, Elsevier

    Manuel Mayr

  173. Guidelines for the functional annotation of microRNAs using the Gene Ontology

    Article • RNA, February 2016, Cold Spring Harbor Laboratory Press

    Manuel Mayr

  174. Association of MicroRNAs and YRNAs With Platelet Function

    Article • Circulation Research, February 2016, Wolters Kluwer Health

    Manuel Mayr

  175. When Sweet Turns Salty

    Article • Journal of the American College of Cardiology, February 2016, Elsevier

    Manuel Mayr

  176. Correlates of serum hepcidin levels and its association with cardiovascular disease in an elderly general population

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2016, De Gruyter

    Manuel Mayr

  177. Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside

    Article • Basic Research in Cardiology, December 2015, Springer Science + Business Media

    Manuel Mayr, Dr. Hector Cabrera-Fuentes

  178. Comparative analysis of statistical methods used for detecting differential expression in label-free mass spectrometry proteomics

    Article • Journal of Proteomics, November 2015, Elsevier

    Manuel Mayr

  179. Inadequate hepcidin serum concentrations predict incident type 2 diabetes mellitus

    Article • Diabetes/Metabolism Research and Reviews, October 2015, Wiley

    Manuel Mayr

  180. MicroRNA Biomarkers for Coronary Artery Disease?

    Article • Current Atherosclerosis Reports, October 2015, Springer Science + Business Media

    Manuel Mayr

  181. XBP 1-Deficiency Abrogates Neointimal Lesion of Injured Vessels Via Cross Talk With the PDGF Signaling

    Article • Arteriosclerosis Thrombosis and Vascular Biology, October 2015, Wolters Kluwer Health

    Manuel Mayr

  182. Angiogenic microRNAs Linked to Incidence and Progression of Diabetic Retinopathy in Type 1 Diabetes

    Article • Diabetes, September 2015, American Diabetes Association

    Manuel Mayr

  183. Transformative Impact of Proteomics on Cardiovascular Health and Disease

    Article • Circulation, September 2015, Wolters Kluwer Health

    Manuel Mayr

  184. Sweet Dicer

    Article • Circulation Research, July 2015, Wolters Kluwer Health

    Manuel Mayr

  185. The cardiovascular gene annotation initiative: Impact on data analysis

    Article • Atherosclerosis, July 2015, Elsevier

    Manuel Mayr

  186. Asymmetric Dimethylarginine and Cardiovascular Risk: Systematic Review and Meta‐Analysis of 22 Prospective Studies

    Article • Journal of the American Heart Association, June 2015, Wolters Kluwer Health

    Manuel Mayr

  187. Novel methodologies for biomarker discovery in atherosclerosis

    Article • European Heart Journal, June 2015, European Society of Cardiology

    Manuel Mayr

  188. Proteomic analyses reveal that loss of TDP-43 affects RNA processing and intracellular transport

    Article • Neuroscience, May 2015, Elsevier

    Manuel Mayr

  189. Vascular Smooth Muscle Cell Calcification Is Mediated by Regulated Exosome Secretion

    Article • Circulation Research, April 2015, Wolters Kluwer Health

    Manuel Mayr

  190. ADAMTS-7 Inhibits Re-endothelialization of Injured Arteries and Promotes Vascular Remodeling Through Cleavage of Thrombospondin-1

    Article • Circulation, March 2015, Wolters Kluwer Health

    Manuel Mayr

  191. T1 values by conservative septal postprocessing approach are superior in relating to the interstitial myocardial fibrosis: findings from patients with severe aortic stenosis

    Article • Journal of Cardiovascular Magnetic Resonance, February 2015, Springer Science + Business Media

    Manuel Mayr

  192. Cardiac-targeted NADPH oxidase 4 in the adaptive cardiac remodelling of the murine heart

    Article • The Lancet, February 2015, Elsevier

    Manuel Mayr

  193. Affinity Proteomics for Phosphatase Interactions in Atrial Fibrillation∗

    Article • Journal of the American College of Cardiology, January 2015, Elsevier

    Manuel Mayr

  194. Native T1 in Discrimination of Acute and Convalescent Stages in Patients With Clinical Diagnosis of Myocarditis

    Article • JACC Cardiovascular Imaging, January 2015, Elsevier

    Manuel Mayr

  195. Lipidomics

    Article • Circulation Cardiovascular Genetics, December 2014, Wolters Kluwer Health

    Manuel Mayr

  196. Role of miR-195 in Aortic Aneurysmal Disease

    Article • Circulation Research, October 2014, Wolters Kluwer Health

    Manuel Mayr

  197. “Going Long”: Long Non-Coding RNAs as Biomarkers

    Article • Circulation Research, September 2014, Wolters Kluwer Health

    Manuel Mayr

  198. Discrimination and Net Reclassification of Cardiovascular Risk With Lipoprotein(a)

    Article • Journal of the American College of Cardiology, September 2014, Elsevier

    Manuel Mayr

  199. Long‐term therapeutic silencing of miR‐33 increases circulating triglyceride levels and hepatic lipid accumulation in mice

    Article • EMBO Molecular Medicine, July 2014, EMBO

    Manuel Mayr

  200. Redox State of Pentraxin 3 as a Novel Biomarker for Resolution of Inflammation and Survival in Sepsis

    Article • Molecular & Cellular Proteomics, June 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Manuel Mayr

  201. Lipidomics Profiling and Risk of Cardiovascular Disease in the Prospective Population-Based Bruneck Study

    Article • Circulation, May 2014, Wolters Kluwer Health

    Dr Massimo Mangino, Dr Cristina Menni, Manuel Mayr

  202. Cardiac fibroblast–derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy

    Article • Journal of Clinical Investigation, April 2014, American Society for Clinical Investigation

    Manuel Mayr

  203. Tracing the Proteomic Fingerprint of the Diabetic Aorta?

    Article • Circulation Cardiovascular Genetics, April 2014, Wolters Kluwer Health

    Manuel Mayr

  204. Targeting myocardial remodelling to develop novel therapies for heart failure

    Article • European Journal of Heart Failure, March 2014, Oxford University Press (OUP)

    Manuel Mayr

  205. Effects of Heparin on Temporal MicroRNA Profiles

    Article • Journal of the American College of Cardiology, March 2014, Elsevier

    Manuel Mayr

  206. ESC Working Group on Myocardial Function Position Paper: how to study the right ventricle in experimental models

    Article • European Journal of Heart Failure, February 2014, Oxford University Press (OUP)

    Manuel Mayr

  207. Signature of circulating microRNAs in osteoarthritis

    Article • Annals of the Rheumatic Diseases, February 2014, BMJ

    Professor Stefan Sesselmann, Manuel Mayr

  208. LDL-receptor-deficient mice lacking microRNA-143/145 have less atherosclerosis

    Article • Thrombosis and Haemostasis, January 2014, Thieme Publishing Group

    Manuel Mayr

  209. Matrix Metalloproteinase-8 Promotes Vascular Smooth Muscle Cell Proliferation and Neointima Formation

    Article • Arteriosclerosis Thrombosis and Vascular Biology, January 2014, Wolters Kluwer Health

    Manuel Mayr

  210. Phosphoregulation of the Titin-cap Protein Telethonin in Cardiac Myocytes

    Article • Journal of Biological Chemistry, January 2014, Elsevier

    Manuel Mayr

  211. Gene Network and Proteomic Analyses of Cardiac Responses to Pathological and Physiological Stress

    Article • Circulation Cardiovascular Genetics, December 2013, Wolters Kluwer Health

    Manuel Mayr

  212. Impaired Antioxidant Defenses and Redox Signaling in GDM Fetal Endothelial Cells

    Article • Diabetes, November 2013, American Diabetes Association

    Manuel Mayr

  213. Histone Deacetylase 3 Unconventional Splicing Mediates Endothelial-to-mesenchymal Transition through Transforming Growth Factor β2

    Article • Journal of Biological Chemistry, November 2013, Elsevier

    Manuel Mayr

  214. Extracellular Matrix Secretion by Cardiac Fibroblasts

    Article • Circulation Research, October 2013, Wolters Kluwer Health

    Manuel Mayr

  215. Multidimensional separation prior to mass spectrometry: Getting closer to the bottom of the iceberg

    Article • PROTEOMICS, October 2013, Wiley

    Manuel Mayr

  216. Oxidative stress in atherosclerosis: The role of microRNAs in arterial remodeling

    Article • Free Radical Biology and Medicine, September 2013, Elsevier

    Manuel Mayr

  217. The Hypoxia-Inducible MicroRNA Cluster miR-199a∼214 Targets Myocardial PPARδ and Impairs Mitochondrial Fatty Acid Oxidation

    Article • Cell Metabolism, September 2013, Elsevier

    Manuel Mayr

  218. Macrophage MicroRNA-155 Promotes Cardiac Hypertrophy and Failure

    Article • Circulation, August 2013, Wolters Kluwer Health

    Dr Kristiaan Wouters, Manuel Mayr

  219. Heterogeneity in Neutrophil Microparticles Reveals Distinct Proteome and Functional Properties

    Article • Molecular & Cellular Proteomics, August 2013, Elsevier

    Prof Jesmond Dalli, Manuel Mayr

  220. Proteomics and Metabolomics for Mechanistic Insights and Biomarker Discovery in Cardiovascular Disease

    Article • Revista Española de Cardiología (English Edition), August 2013, Elsevier

    Manuel Mayr

  221. Vascular Proteomics - The Forgotten Blood Vessels

    Article • PROTEOMICS - CLINICAL APPLICATIONS, August 2013, Wiley

    Manuel Mayr

  222. La proteómica y la metabolómica: los mecanismos de la enfermedad cardiovascular y el descubrimiento de biomarcadores

    Article • Revista Española de Cardiología, August 2013, Elsevier

    Manuel Mayr

  223. MicroRNA biomarkers for failing hearts?

    Article • European Heart Journal, July 2013, European Society of Cardiology

    Manuel Mayr

  224. Proteomics in aortic aneurysm - What have we learnt so far?

    Article • PROTEOMICS - CLINICAL APPLICATIONS, July 2013, Wiley

    Manuel Mayr

  225. Endothelial Seeding for Abdominal Aortic Aneurysms

    Article • Circulation, May 2013, Wolters Kluwer Health

    Manuel Mayr

  226. Glycoproteomic Analysis of the Secretome of Human Endothelial Cells

    Article • Molecular & Cellular Proteomics, April 2013, Elsevier

    Manuel Mayr

  227. Native T1 Mapping in Differentiation of Normal Myocardium From Diffuse Disease in Hypertrophic and Dilated Cardiomyopathy

    Article • JACC Cardiovascular Imaging, April 2013, Elsevier

    Manuel Mayr

  228. Circulating MicroRNAs as Novel Biomarkers for Platelet Activation

    Article • Circulation Research, February 2013, Wolters Kluwer Health

    Manuel Mayr

  229. From data gathering to systems medicine

    Article • Cardiovascular Research, February 2013, European Society of Cardiology

    Manuel Mayr

  230. Effects of perhexiline-induced fuel switch on the cardiac proteome and metabolome

    Article • Journal of Molecular and Cellular Cardiology, February 2013, Elsevier

    Manuel Mayr

  231. MicroRNAs Within the Continuum of Postgenomics Biomarker Discovery

    Article • Arteriosclerosis Thrombosis and Vascular Biology, February 2013, Wolters Kluwer Health

    Manuel Mayr

  232. Proteomic Identification of Matrix Metalloproteinase Substrates in the Human Vasculature

    Article • Circulation Cardiovascular Genetics, February 2013, Wolters Kluwer Health

    Manuel Mayr

  233. Functional Role of Matrix Metalloproteinase-8 in Stem/Progenitor Cell Migration and Their Recruitment Into Atherosclerotic Lesions

    Article • Circulation Research, January 2013, Wolters Kluwer Health

    Manuel Mayr

  234. Impact of intravenous heparin on quantification of circulating microRNAs in patients with coronary artery disease

    Article • Thrombosis and Haemostasis, January 2013, Thieme Publishing Group

    Manuel Mayr

  235. A Sequential Extraction Methodology for Cardiac Extracellular Matrix Prior to Proteomics Analysis

    Article • January 2013, Springer Science + Business Media

    Manuel Mayr

  236. Cytochrome P4502S1: a novel monocyte/macrophage fatty acid epoxygenase in human atherosclerotic plaques

    Article • Basic Research in Cardiology, December 2012, Springer Science + Business Media

    Professor Ingrid Fleming, Manuel Mayr

  237. Proteomics: from single molecules to biological pathways

    Article • Cardiovascular Research, November 2012, European Society of Cardiology

    Manuel Mayr

  238. Oxidation-Specific Biomarkers, Prospective 15-Year Cardiovascular and Stroke Outcomes, and Net Reclassification of Cardiovascular Events

    Article • Journal of the American College of Cardiology, November 2012, Elsevier

    Manuel Mayr

  239. Calpain inhibition stabilizes the platelet proteome and reactivity in diabetes

    Article • Blood, July 2012, American Society of Hematology

    Manuel Mayr

  240. Prospective Study on Circulating MicroRNAs and Risk of Myocardial Infarction

    Article • Journal of the American College of Cardiology, July 2012, Elsevier

    Manuel Mayr

  241. Novel Role of ADAMTS-5 Protein in Proteoglycan Turnover and Lipoprotein Retention in Atherosclerosis

    Article • Journal of Biological Chemistry, June 2012, Elsevier

    Manuel Mayr

  242. European Perspectives

    Article • Circulation, May 2012, Wolters Kluwer Health

    Manuel Mayr

  243. The -omics era: Proteomics and lipidomics in vascular research

    Article • Atherosclerosis, March 2012, Elsevier

    Manuel Mayr

  244. Proteomics Analysis of Cardiac Extracellular Matrix Remodeling in a Porcine Model of Ischemia/Reperfusion Injury

    Article • Circulation, February 2012, Wolters Kluwer Health

    Manuel Mayr

  245. Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs

    Article • Nature Cell Biology, February 2012, Springer Science + Business Media

    Manuel Mayr

  246. Review focus on the role of microRNA in cardiovascular biology and disease

    Article • Cardiovascular Research, February 2012, European Society of Cardiology

    Manuel Mayr

  247. MicroRNAs in Vascular and Metabolic Disease

    Article • Circulation Research, February 2012, Wolters Kluwer Health

    Manuel Mayr

  248. Analytical challenges and technical limitations in assessing circulating MiRNAs

    Article • Thrombosis and Haemostasis, January 2012, Thieme Publishing Group

    Manuel Mayr

  249. Pathogenesis of Varicose Veins

    Article • Journal of Vascular and Interventional Radiology, January 2012, Elsevier

    Manuel Mayr

  250. Method for Protein Subfractionation of Cardiovascular Tissues Before DIGE Analysis

    Article • January 2012, Springer Science + Business Media

    Manuel Mayr

  251. Proteomics of Atherosclerosis

    Article • November 2011, Springer Science + Business Media

    Manuel Mayr

  252. Terminal Differentiation, Advanced Organotypic Maturation, and Modeling of Hypertrophic Growth in Engineered Heart Tissue

    Article • Circulation Research, October 2011, Wolters Kluwer Health

    Manuel Mayr

  253. Profiling of circulating microRNAs: from single biomarkers to re-wired networks

    Article • Cardiovascular Research, October 2011, European Society of Cardiology

    Manuel Mayr

  254. Chromobox Protein Homolog 3 Is Essential for Stem Cell Differentiation to Smooth Muscles In Vitro and in Embryonic Arteriogenesis

    Article • Arteriosclerosis Thrombosis and Vascular Biology, August 2011, Wolters Kluwer Health

    Manuel Mayr

  255. Extracellular Matrix Composition and Remodeling in Human Abdominal Aortic Aneurysms: A Proteomics Approach

    Article • Molecular & Cellular Proteomics, August 2011, Elsevier

    Manuel Mayr

  256. Nitrosative protein oxidation is modulated during early endotoxemia

    Article • Nitric Oxide, August 2011, Elsevier

    Manuel Mayr

  257. Recent Highlights of Metabolomics in Cardiovascular Research

    Article • Circulation Cardiovascular Genetics, August 2011, Wolters Kluwer Health

    Manuel Mayr

  258. Substrate Modifications Precede the Development of Atrial Fibrillation After Cardiac Surgery: A Proteomic Study

    Article • The Annals of Thoracic Surgery, July 2011, Elsevier

    Manuel Mayr

  259. Calcium Regulates Key Components of Vascular Smooth Muscle Cell–Derived Matrix Vesicles to Enhance Mineralization

    Article • Circulation Research, June 2011, Wolters Kluwer Health

    Manuel Mayr

  260. Comparative Lipidomics Profiling of Human Atherosclerotic Plaques

    Article • Circulation Cardiovascular Genetics, June 2011, Wolters Kluwer Health

    Manuel Mayr

  261. From Bench to Bedside: What Physicians Need to Know About Endothelial Progenitor Cells

    Article • The American Journal of Medicine, June 2011, Elsevier

    Manuel Mayr

  262. Metabolic homeostasis is maintained in myocardial hibernation by adaptive changes in the transcriptome and proteome

    Article • Journal of Molecular and Cellular Cardiology, June 2011, Elsevier

    Manuel Mayr

  263. Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas

    Article • BMC Cancer, May 2011, Springer Science + Business Media

    Manuel Mayr

  264. Proteomics

    Article • Circulation Research, February 2011, Wolters Kluwer Health

    Manuel Mayr

  265. Redox Regulation of Soluble Epoxide Hydrolase by 15-Deoxy-Δ-Prostaglandin J 2 Controls Coronary Hypoxic Vasodilation

    Article • Circulation Research, February 2011, Wolters Kluwer Health

    Manuel Mayr

  266. Cardiovascular stem cells revisited

    Article • Journal of Molecular and Cellular Cardiology, February 2011, Elsevier

    Manuel Mayr

  267. Proteomic characterization of human early pro-angiogenic cells

    Article • Journal of Molecular and Cellular Cardiology, February 2011, Elsevier

    Manuel Mayr

  268. Does Late Enhancement Imaging Decipher the Role of Myocardial Fibrosis in Hypertrophic Cardiomyopathy?

    Article • Current Cardiovascular Imaging Reports, January 2011, Springer Science + Business Media

    Manuel Mayr

  269. Preoperative high-dose atorvastatin for prevention of atrial fibrillation after cardiac surgery: A randomized controlled trial

    Article • Journal of Thoracic and Cardiovascular Surgery, January 2011, Elsevier

    Manuel Mayr

  270. Highlights from the 2010 BAS/BSCR spring meeting: New Frontiers in Cardiovascular Research

    Article • Expert Review of Proteomics, December 2010, Taylor & Francis

    Manuel Mayr

  271. Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes

    Article • Circulation Research, September 2010, Wolters Kluwer Health

    Manuel Mayr

  272. Human cardiac and bone marrow stromal cells exhibit distinctive properties related to their origin

    Article • Cardiovascular Research, September 2010, European Society of Cardiology

    Manuel Mayr

  273. Proteomics Characterization of Extracellular Space Components in the Human Aorta

    Article • Molecular & Cellular Proteomics, September 2010, Elsevier

    Manuel Mayr

  274. Short Communication: Asymmetric Dimethylarginine Impairs Angiogenic Progenitor Cell Function in Patients With Coronary Artery Disease Through a MicroRNA-21–Dependent Mechanism

    Article • Circulation Research, July 2010, Wolters Kluwer Health

    Manuel Mayr

  275. Comparative Proteomics Profiling Reveals Role of Smooth Muscle Progenitors in Extracellular Matrix Production

    Article • Arteriosclerosis Thrombosis and Vascular Biology, July 2010, Wolters Kluwer Health

    Manuel Mayr

  276. Coupling Vascular and Myocardial Inflammatory Injury into a Common Phenotype of Cardiovascular Dysfunction: Systemic Inflammation and Aging – A Mini-Review

    Article • Gerontology, June 2010, Karger Publishers

    Manuel Mayr

  277. Histone Deacetylase 7 Controls Endothelial Cell Growth Through Modulation of β-Catenin

    Article • Circulation Research, April 2010, Wolters Kluwer Health

    Manuel Mayr

  278. Phenotyping transgenic animals—An integrated readout of pathophysiology by combining proteomics and metabolomics with cardiovascular imaging

    Article • Journal of Molecular and Cellular Cardiology, April 2010, Elsevier

    Manuel Mayr

  279. Proteomics Analysis of the Cardiac Myofilament Subproteome Reveals Dynamic Alterations in Phosphatase Subunit Distribution

    Article • Molecular & Cellular Proteomics, March 2010, Elsevier

    Manuel Mayr

  280. Proteomic analysis of the secretome of human umbilical vein endothelial cells using a combination of free-flow electrophoresis and nanoflow LC-MS/MS

    Article • PROTEOMICS, October 2009, Wiley

    Manuel Mayr

  281. Identification of Cardiac Myosin-binding Protein C as a Candidate Biomarker of Myocardial Infarction by Proteomics Analysis

    Article • Molecular & Cellular Proteomics, August 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Pierre Sicard, Manuel Mayr

  282. Proteomics, Metabolomics, and Immunomics on Microparticles Derived From Human Atherosclerotic Plaques

    Article • Circulation Cardiovascular Genetics, August 2009, Wolters Kluwer Health

    Manuel Mayr

  283. Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures

    Article • Blood, July 2009, American Society of Hematology

    Manuel Mayr

  284. Asymmetric and symmetric dimethylarginines are of similar predictive value for cardiovascular risk in the general population

    Article • Atherosclerosis, July 2009, Elsevier

    Manuel Mayr

  285. Proteomics of acute coronary syndromes

    Article • Current Atherosclerosis Reports, April 2009, Springer Science + Business Media

    Manuel Mayr

  286. Proteomic and metabolomic analysis of cardioprotection: Interplay between protein kinase C epsilon and delta in regulating glucose metabolism of murine hearts

    Article • Journal of Molecular and Cellular Cardiology, February 2009, Elsevier

    Manuel Mayr

  287. Proteomics Identifies Thymidine Phosphorylase As a Key Regulator of the Angiogenic Potential of Colony-Forming Units and Endothelial Progenitor Cell Cultures

    Article • Circulation Research, January 2009, Wolters Kluwer Health

    Manuel Mayr

  288. Metabolomics

    Article • Circulation Cardiovascular Genetics, October 2008, Wolters Kluwer Health

    Manuel Mayr

  289. Lipoprotein-associated phospholipase A2 activity, ferritin levels, metabolic syndrome, and 10-year cardiovascular and non-cardiovascular mortality: results from the Bruneck study

    Article • European Heart Journal, July 2008, European Society of Cardiology

    Manuel Mayr

  290. Letter by Metzler et al Regarding Article, “Intracoronary KAI-9803 as an Adjunct to Primary Coronary Intervention for Acute ST-Segment Elevation Myocardial Infarction”

    Article • Circulation, July 2008, Wolters Kluwer Health

    Manuel Mayr

  291. Cardiovascular Proteomics

    Article • PROTEOMICS - CLINICAL APPLICATIONS, June 2008, Wiley

    Manuel Mayr

  292. Proteomic analysis of secretory proteins and vesicles in vascular research

    Article • PROTEOMICS - CLINICAL APPLICATIONS, June 2008, Wiley

    Manuel Mayr

  293. Proteomic and Metabolomic Analysis of Smooth Muscle Cells Derived From the Arterial Media and Adventitial Progenitors of Apolipoprotein E–Deficient Mice

    Article • Circulation Research, May 2008, Wolters Kluwer Health

    Professor Paul HA Quax, Manuel Mayr

  294. The Paradox of Hypoxic and Oxidative Stress in Atherosclerosis⁎⁎Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Car...

    Article • Journal of the American College of Cardiology, April 2008, Elsevier

    Manuel Mayr

  295. Combined Metabolomic and Proteomic Analysis of Human Atrial Fibrillation

    Article • Journal of the American College of Cardiology, February 2008, Elsevier

    Manuel Mayr

  296. Integrated Membrane Protein Analysis of Mature and Embryonic Stem Cell-derived Smooth Muscle Cells Using a Novel Combination of CyDye/Biotin Labeling

    Article • Molecular & Cellular Proteomics, October 2007, Elsevier

    Manuel Mayr

  297. Oxidized Phospholipids, Lipoprotein(a), Lipoprotein-Associated Phospholipase A2 Activity, and 10-Year Cardiovascular Outcomes

    Article • Arteriosclerosis Thrombosis and Vascular Biology, August 2007, Wolters Kluwer Health

    Manuel Mayr

  298. Protein Kinase D Selectively Targets Cardiac Troponin I and Regulates Myofilament Ca 2+ Sensitivity in Ventricular Myocytes

    Article • Circulation Research, March 2007, Wolters Kluwer Health

    Manuel Mayr

  299. Proteomics and Metabolomics Combined in Cardiovascular Research

    Article • Trends in Cardiovascular Medicine, February 2007, Elsevier

    Manuel Mayr

  300. Proteomic analysis reveals higher demand for antioxidant protection in embryonic stem cell-derived smooth muscle cells

    Article • PROTEOMICS, December 2006, Wiley

    Manuel Mayr

  301. The role of oxidant stress in angiotensin II-mediated contraction of human resistance arteries in the state of health and the presence of cardiovascular disease

    Article • Vascular Pharmacology, December 2006, Elsevier

    Manuel Mayr

  302. Proteomics-based Development of Biomarkers in Cardiovascular Disease

    Article • Molecular & Cellular Proteomics, October 2006, Elsevier

    Manuel Mayr

  303. Oxidized Low-Density Lipoprotein Autoantibodies, Chronic Infections, and Carotid Atherosclerosis in a Population-Based Study

    Article • Journal of the American College of Cardiology, June 2006, Elsevier

    Manuel Mayr

  304. Oxidized Phospholipids Predict the Presence and Progression of Carotid and Femoral Atherosclerosis and Symptomatic Cardiovascular Disease

    Article • Journal of the American College of Cardiology, June 2006, Elsevier

    Manuel Mayr

  305. Association of Serum-Soluble Heat Shock Protein 60 With Carotid Atherosclerosis

    Article • Stroke, December 2005, Wolters Kluwer Health

    Manuel Mayr

  306. Metabolic profiling of hypoxia-inducible factor-1β-deficient and wild type Hepa-1 cells: effects of hypoxia measured by 1H magnetic resonance spectroscopy

    Article • Metabolomics, October 2005, Springer Science + Business Media

    Manuel Mayr

  307. Proteomic dataset of Sca-1+ progenitor cells

    Article • PROTEOMICS, October 2005, Wiley

    Manuel Mayr

  308. Proteomic dataset of mouse aortic smooth muscle cells

    Article • PROTEOMICS, October 2005, Wiley

    Manuel Mayr

  309. Proteomic and Metabolomic Analyses of Atherosclerotic Vessels From Apolipoprotein E-Deficient Mice Reveal Alterations in Inflammation, Oxidative Stress, and Energy Metabolism

    Article • Arteriosclerosis Thrombosis and Vascular Biology, October 2005, Wolters Kluwer Health

    Manuel Mayr

  310. Role of oxidative stress in angiotensin-II mediated contraction of human conduit arteries in patients with cardiovascular disease

    Article • Vascular Pharmacology, October 2005, Elsevier

    Manuel Mayr

  311. Vascular proteomics: Linking proteomic and metabolomic changes

    Article • PROTEOMICS, December 2004, Wiley

    Manuel Mayr

  312. Pitfalls of Proteomics

    Article • Circulation, September 2004, Wolters Kluwer Health

    Manuel Mayr

  313. Ischemic preconditioning exaggerates cardiac damage in PKC-δ null mice

    Article • AJP Heart and Circulatory Physiology, August 2004, American Physiological Society

    Manuel Mayr

  314. Loss of PKC-δ alters cardiac metabolism

    Article • AJP Heart and Circulatory Physiology, August 2004, American Physiological Society

    Manuel Mayr

  315. Proteomic and Metabolomic Analysis of Vascular Smooth Muscle Cells

    Article • Circulation Research, May 2004, Wolters Kluwer Health

    Manuel Mayr

  316. Cross-Reactive B-Cell Epitopes of Microbial and Human Heat Shock Protein 60/65 in Atherosclerosis

    Article • Arteriosclerosis Thrombosis and Vascular Biology, June 2003, Wolters Kluwer Health

    Manuel Mayr

  317. Mechanical Stretch-Induced Apoptosis in Smooth Muscle Cells Is Mediated by β 1 -Integrin Signaling Pathways

    Article • Hypertension, April 2003, Wolters Kluwer Health

    Manuel Mayr

  318. Increased Risk of Atherosclerosis Is Confined to CagA-Positive Helicobacter pylori Strains

    Article • Stroke, March 2003, Wolters Kluwer Health

    Manuel Mayr

  319. Both Donor and Recipient Origins of Smooth Muscle Cells in Vein Graft Atherosclerotic Lesions

    Article • Circulation Research, October 2002, Wolters Kluwer Health

    Manuel Mayr

  320. Smooth Muscle Cells in Transplant Atherosclerotic Lesions Are Originated From Recipients, but Not Bone Marrow Progenitor Cells

    Article • Circulation, October 2002, Wolters Kluwer Health

    Manuel Mayr

  321. Active and Passive Smoking, Chronic Infections, and the Risk of Carotid Atherosclerosis

    Article • Stroke, September 2002, Wolters Kluwer Health

    Manuel Mayr

  322. Mechanical Stress‐induced DNA damage and rac‐p38MAPK Signal Pathways Mediate p53‐dependent Apoptosis in Vascular Smooth Muscle Cells

    Article • The FASEB Journal, July 2002, Wiley

    Manuel Mayr

  323. Loss of p53 Accelerates Neointimal Lesions of Vein Bypass Grafts in Mice

    Article • Circulation Research, February 2002, Wolters Kluwer Health

    Manuel Mayr

  324. Exacerbated vein graft arteriosclerosis in protein kinase Cδ–null mice

    Article • Journal of Clinical Investigation, November 2001, American Society for Clinical Investigation

    Manuel Mayr

  325. Smooth muscle cell apoptosis in arteriosclerosis

    Article • Experimental Gerontology, July 2001, Elsevier

    Manuel Mayr

  326. Chronic Infections and the Risk of Carotid Atherosclerosis

    Article • Circulation, February 2001, Wolters Kluwer Health

    Manuel Mayr

  327. Infections, Immunity, and Atherosclerosis

    Article • Circulation, August 2000, Wolters Kluwer Health

    Manuel Mayr

  328. Rapid Development of Vein Graft Atheroma in ApoE-Deficient Mice

    Article • American Journal Of Pathology, August 2000, Elsevier

    Manuel Mayr

  329. Serum Soluble Heat Shock Protein 60 Is Elevated in Subjects With Atherosclerosis in a General Population

    Article • Circulation, July 2000, Wolters Kluwer Health

    Manuel Mayr

  330. Reduced Neointima Hyperplasia of Vein Bypass Grafts in Intercellular Adhesion Molecule-1–Deficient Mice

    Article • Circulation Research, March 2000, Wolters Kluwer Health

    Manuel Mayr

  331. Association of Serum Antibodies to Heat-Shock Protein 65 With Carotid Atherosclerosis

    Article • Circulation, September 1999, Wolters Kluwer Health

    Manuel Mayr

  332. Cyclic Strain Stress-induced Mitogen-activated Protein Kinase (MAPK) Phosphatase 1 Expression in Vascular Smooth Muscle Cells Is Regulated by Ras/Rac-MAPK Pathways

    Article • Journal of Biological Chemistry, September 1999, Elsevier

    Manuel Mayr

  333. Inhibition of Arteriosclerosis by T-Cell Depletion in Normocholesterolemic Rabbits Immunized With Heat Shock Protein 65

    Article • Arteriosclerosis Thrombosis and Vascular Biology, August 1999, Wolters Kluwer Health

    Manuel Mayr

  334. Endothelial Cytotoxicity Mediated by Serum Antibodies to Heat Shock Proteins of Escherichia coli and Chlamydia pneumoniae

    Article • Circulation, March 1999, Wolters Kluwer Health

    Manuel Mayr

  335. Macrophage-lysis mediated by autoantibodies to heat shock protein 65/60

    Article • Atherosclerosis, January 1997, Elsevier

    Manuel Mayr