All Stories

  1. Synthesis, Molecular Docking, c-Met Inhibitions of 2,2,2-Trichloroethylidene- cyclohexane-1, 3-dione Derivatives Together with their Application as Target SARS-CoV-2 main Protease (Mpro) and as Potential anti-COVID-19

    Article • Combinatorial Chemistry & High Throughput Screening, June 2023, Bentham Science Publishers

    Dr Ali S Abdelhameed, Mahmoud Mahmoud

  2. Antiproliferative activity and possible mechanism of action of certain 5-methoxyindole tethered C-5 functionalized isatins

    Article • Drug Design Development and Therapy, August 2019, Taylor & Francis

    Dr Ali S Abdelhameed

  3. Validated LC-MS/MS assay for quantification of the newly approved tyrosine kinase inhibitor, dacomitinib, and application to investigating its metabolic stability

    Article • PLoS ONE, April 2019, PLOS

    Dr Ali S Abdelhameed

  4. Deciphering the enhanced inhibitory, disaggregating and cytoprotective potential of promethazine towards amyloid fibrillation

    Article • International Journal of Biological Macromolecules, January 2018, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  5. Probing the interaction of cephalosporin antibiotic–ceftazidime with human serum albumin: A biophysical investigation

    Article • International Journal of Biological Macromolecules, December 2017, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  6. Biophysical and In Silico Studies of the Interaction between the Anti-Viral Agents Acyclovir and Penciclovir, and Human Serum Albumin

    Article • Molecules, November 2017, MDPI AG

    Dr Ali S Abdelhameed

  7. Cationic surfactant mediated fibrillogenesis in bovine liver catalase: a biophysical approach

    Article • Journal of Biomolecular Structure and Dynamics, August 2017, Taylor & Francis

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  8. Isatin-benzoazine molecular hybrids as potential antiproliferative agents: synthesis and in vitro pharmacological profiling

    Article • Drug Design Development and Therapy, August 2017, Dove Medical Press

    Dr Ali S Abdelhameed, Mohamed Attwa, Wagdy Eldehna

  9. Exploring the interaction forces involved in the binding of the multiple myeloma drug lenalidomide to bovine serum albumin

    Article • Journal of Molecular Liquids, July 2017, Elsevier

    Dr Ali S Abdelhameed

  10. Synthesis and Biophysical Insights into the Binding of a Potent Anti-Proliferative Non-symmetric Bis-isatin Derivative with Bovine Serum Albumin: Spectroscopic and Molecular Docking Approaches

    Article • Applied Sciences, June 2017, MDPI AG

    Dr Ali S Abdelhameed, Wagdy Eldehna

  11. Anti-Parkinsonian L-Dopa can also act as anti-systemic amyloidosis—A mechanistic exploration

    Article • International Journal of Biological Macromolecules, June 2017, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  12. Ascorbic acid inhibits human insulin aggregation and protects against amyloid induced cytotoxicity

    Article • Archives of Biochemistry and Biophysics, May 2017, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  13. Biophysical insight reveals tannic acid as amyloid inducer and conformation transformer from amorphous to amyloid aggregates in Concanavalin A (ConA)

    Article • Journal of Biomolecular Structure and Dynamics, April 2017, Taylor & Francis

    Dr Ali S Abdelhameed, Rizwan KHAN, Professor Rizwan Hasan Khan

  14. A multitechnique approach to probe the interaction of a therapeutic tyrosine kinase inhibitor nintedanib and bovine serum albumin

    Article • Preparative Biochemistry & Biotechnology, February 2017, Taylor & Francis

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  15. Liquid chromatographic-tandem mass spectrometric assay for simultaneous quantitation of tofacitinib, cabozantinib and afatinib in human plasma and urine

    Article • Tropical Journal of Pharmaceutical Research, January 2017, African Journals Online (AJOL)

    Dr Ali S Abdelhameed

  16. Fluorescence spectroscopic and molecular docking studies of the binding interaction between the new anaplastic lymphoma kinase inhibitor crizotinib and bovine serum albumin

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, January 2017, Elsevier

    Dr Ali S Abdelhameed

  17. Polyols (Glycerol and Ethylene glycol) mediated amorphous aggregate inhibition and secondary structure restoration of metalloproteinase-conalbumin (ovotransferrin)

    Article • International Journal of Biological Macromolecules, January 2017, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  18. A biophysical and computational study unraveling the molecular interaction mechanism of a new Janus kinase inhibitor Tofacitinib with bovine serum albumin

    Article • Journal of Molecular Recognition, December 2016, Wiley

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  19. Mechanisms of protein misfolding: Novel therapeutic approaches to protein-misfolding diseases

    Article • Journal of Molecular Structure, November 2016, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  20. Solution conformation and flexibility of capsular polysaccharides from Neisseria meningitidis and glycoconjugates with the tetanus toxoid protein

    Article • Scientific Reports, October 2016, Nature

    Dr Ali S Abdelhameed

  21. Correction: A Comprehensive Spectroscopic and Computational Investigation to Probe the Interaction of Antineoplastic Drug Nordihydroguaiaretic Acid with Serum Albumins

    Article • PLoS ONE, October 2016, PLOS

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  22. An LC-MS/MS method for rapid and sensitive high-throughput simultaneous determination of various protein kinase inhibitors in human plasma

    Article • Biomedical Chromatography, August 2016, Wiley

    Dr Ali S Abdelhameed

  23. Liquid chromatographic-mass spectrometric method for determination of drug content uniformity of two commonly used dermatology medications in a split-tablet dosage form

    Article • Tropical Journal of Pharmaceutical Research, July 2016, African Journals Online (AJOL)

    Dr Ali S Abdelhameed, Mohamed Attwa

  24. A Comprehensive Spectroscopic and Computational Investigation to Probe the Interaction of Antineoplastic Drug Nordihydroguaiaretic Acid with Serum Albumins

    Article • PLoS ONE, July 2016, PLOS

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  25. Interaction of the recently approved anticancer drug nintedanib with human acute phase reactant α 1-acid glycoprotein

    Article • Journal of Molecular Structure, July 2016, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  26. A novel method to determine new potent angiotensin inhibitor, azilsartan, in human plasma via micelle-enhanced spectrofluorimetry using cremophor RH 40

    Article • Tropical Journal of Pharmaceutical Research, May 2016, African Journals Online (AJOL)

    Dr Ali S Abdelhameed

  27. Binding of Janus kinase inhibitor tofacitinib with human serum albumin: multi-technique approach

    Article • Journal of Biomolecular Structure and Dynamics, May 2016, Taylor & Francis

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  28. Structure of amyloid oligomers and their mechanisms of toxicities: Targeting amyloid oligomers using novel therapeutic approaches

    Article • European Journal of Medicinal Chemistry, May 2016, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  29. Interplay of multiple interaction forces: Binding of tyrosine kinase inhibitor nintedanib with human serum albumin

    Article • Journal of Photochemistry and Photobiology B Biology, April 2016, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  30. Interaction of new kinase inhibitors cabozantinib and tofacitinib with human serum alpha-1 acid glycoprotein. A comprehensive spectroscopic and molecular Docking approach

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, April 2016, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  31. A glycoconjugate of Haemophilus influenzae Type b capsular polysaccharide with tetanus toxoid protein: hydrodynamic properties mainly influenced by the carbohydrate

    Article • Scientific Reports, February 2016, Nature

    Dr Ali S Abdelhameed

  32. A highly efficient and sensitive LC-MS/MS method for the determination of afatinib in human plasma: application to a metabolic stability study

    Article • Biomedical Chromatography, January 2016, Wiley

    Dr Ali S Abdelhameed

  33. A Spectroscopic Approach to Investigate the Molecular Interactions between the Newly Approved Irreversible ErbB blocker "Afatinib" and Bovine Serum Albumin

    Article • PLoS ONE, January 2016, PLOS

    Dr Ali S Abdelhameed

  34. Simultaneous quantitative analysis of olmesartan, amlodipine and hydrochlorothiazide in their combined dosage form utilizing classical and alternating least squares based chemometric methods

    Article • Acta Pharmaceutica, January 2016, De Gruyter

    Dr Ali S Abdelhameed

  35. Effect of galactose on acid induced molten globule state of Soybean Agglutinin: Biophysical approach

    Article • Journal of Molecular Structure, November 2015, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  36. Experimental and Theoretical Studies of the Vibrational and Electronic Properties of (2E)-2-[3-(1H-imidazol-1-yl)-1-phenyl-propylidene]-N-phenylhydrazinecarboxamide: An Anticonvulsant Agent

    Article • Applied Sciences, October 2015, MDPI AG

    Dr Ali S Abdelhameed

  37. Erratum to: Biophysical Interactions of Novel Oleic Acid Conjugate and its Anticancer Potential in HeLa Cells

    Article • Journal of Fluorescence, March 2015, Springer Science + Business Media

    Dr Ali S Abdelhameed

  38. Biophysical Interactions of Novel Oleic Acid Conjugate and its Anticancer Potential in HeLa Cells

    Article • Journal of Fluorescence, February 2015, Springer Science + Business Media

    Dr Ali S Abdelhameed

  39. A new method to determine the new C-Met inhibitor “Cabozantinib” in dosage form and human plasma via micelle-enhanced spectrofluorimetry

    Article • RSC Advances, January 2015, Royal Society of Chemistry

    Dr Ali S Abdelhameed

  40. Spectrofluorimetric study of finasteride and bovine serum albumin interaction and its application for quantitative determination of finasteride in tablet dosage form

    Article • Analytical Methods, January 2015, Royal Society of Chemistry

    Dr Ali S Abdelhameed

  41. Nanosuspension: An Emerging Trend for Bioavailability Enhancement of Etodolac

    Article • International Journal of Polymer Science, January 2015, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed

  42. Insight into the Interaction between the HIV-1 Integrase Inhibitor Elvitegravir and Bovine Serum Albumin: A Spectroscopic Study

    Article • Journal of Spectroscopy, January 2015, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed

  43. Characterization of Capsular Polysaccharides and Their Glycoconjugates by Hydrodynamic Methods

    Article • January 2015, Springer Science + Business Media

    Dr Ali S Abdelhameed

  44. Micellar Enhanced Spectrofluorimetric Method for the Determination of Ponatinib in Human Plasma and Urine via Cremophor RH 40 as Sensing Agent

    Article • International Journal of Analytical Chemistry, January 2015, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed

  45. HPLC method with monolithic column for simultaneous determination of irbesartan and hydrochlorothiazide in tablets

    Article • Acta Pharmaceutica, June 2014, De Gruyter

    Dr Ali S Abdelhameed

  46. A Validated HPLC-DAD Method for Simultaneous Determination of Etodolac and Pantoprazole in Rat Plasma

    Article • Journal of Chemistry, January 2014, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed

  47. Pseudo-MS3Approach Using Electrospray Mass Spectrometry (ESI-MS/MS) to Characterize Certain (2E)-2-[3-(1H-Imidazol-1-yl)-1-phenylpropylidene]hydrazinecarboxamide Derivatives

    Article • Journal of Chemistry, January 2014, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed, Mohamed Attwa

  48. A Stability-Indicating HPLC-DAD Method for Determination of Stiripentol: Development, Validation, Kinetics, Structure Elucidation and Application to Commercial Dosage Form

    Article • Journal of Analytical Methods in Chemistry, January 2014, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed

  49. Multistage Fragmentation of Ion Trap Mass Spectrometry System and Pseudo-MS3of Triple Quadrupole Mass Spectrometry Characterize Certain (E)-3-(Dimethylamino)-1-arylprop-2-en-1-ones: A Comparative Study

    Article • The Scientific World JOURNAL, January 2014, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed

  50. Characterization and Anticancer Potential of Newly Synthesized Propofol Conjugates

    Article • Asian Journal of Chemistry, January 2014, Asian Journal of Chemistry

    Dr Ali S Abdelhameed

  51. Induced in-source fragmentation pattern of certain novel (1Z,2E)-N-(aryl)propanehydrazonoyl chlorides by electrospray mass spectrometry (ESI-MS/MS)

    Article • Chemistry Central Journal, January 2013, Springer Science + Business Media

    Dr Ali S Abdelhameed

  52. Comparative ANNs with Different Input Layers and GA-PLS Study for Simultaneous Spectrofluorimetric Determination of Melatonin and Pyridoxine HCl in the Presence of Melatonin’s Main Impurity

    Article • Molecules, January 2013, MDPI AG

    Dr Ali S Abdelhameed

  53. High Throughput Quantitative Bioanalytical LC/MS/MS Determination of Gemifloxacin in Human Urine

    Article • Journal of Chemistry, January 2013, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed, Mohamed Attwa

  54. An asymmetric and slightly dimerized structure for the tetanus toxoid protein used in glycoconjugate vaccines

    Article • Carbohydrate Polymers, November 2012, Elsevier

    Dr Gordon A. Morris, Dr Ali S Abdelhameed

  55. Solution properties of capsular polysaccharides from Streptococcus pneumoniae

    Article • Carbohydrate Polymers, September 2012, Elsevier

    Dr Gordon A. Morris, Dr Ali S Abdelhameed

  56. Extended Fujita approach to the molecular weight distribution of polysaccharides and other polymeric systems

    Article • Methods, May 2011, Elsevier

    Dr Gordon A. Morris, Dr Ali S Abdelhameed

  57. On the hydrodynamic analysis of conformation in mixed biopolymer systems

    Article • Polymer International, October 2010, Wiley

    Dr Gordon A. Morris, Dr Ali S Abdelhameed

  58. Molecular Weight Distribution Evaluation of Polysaccharides and Glycoconjugates Using Analytical Ultracentrifugation

    Article • Macromolecular Bioscience, July 2010, Wiley

    Dr Gordon A. Morris, Dr Ali S Abdelhameed

  59. An analytical ultracentrifuge study on ternary mixtures of konjac glucomannan supplemented with sodium alginate and xanthan gum

    Article • Carbohydrate Polymers, May 2010, Elsevier

    Dr Gordon A. Morris, Dr Ali S Abdelhameed

  60. A novel global hydrodynamic analysis of the molecular flexibility of the dietary fibre polysaccharide konjac glucomannan

    Article • Food Hydrocolloids, October 2009, Elsevier

    Dr Gordon A. Morris, Dr Ali S Abdelhameed