All Stories

  1. C-Ring Structure-Dependent Redox Properties of Flavonoids Regulate the Expression of Bioactivity

    Article • Antioxidants, February 2026, MDPI AG

    Dr Ali S Abdelhameed

  2. Estimation of the metabolic stability of omipalisib in human liver microsomes employing an ultra-fast UPLC-MS/MS approach: in silico screening for structural alarms and metabolic lability

    Article • Analytical Methods, January 2026, Royal Society of Chemistry

    Dr Ali S Abdelhameed

  3. Quantification of buparlisib in human liver microsomes employing an ultra-fast, sensitive UPLC-MS/MS method: in vitro and in silico metabolic stability evalua...

    Article • The Analyst, January 2026, Royal Society of Chemistry

    Dr Ali S Abdelhameed

  4. Green Ultra‐Fast UPLC–MS/MS Method for Enasidenib Quantification in HLMs Matrix With the Metabolic Stability Assessment: In Silico Study for Structural Alerts, ADME Characteristics and Metaboslic Lability

    Article • Biomedical Chromatography, December 2025, Wiley

    Dr Ali S Abdelhameed

  5. Mitigating testicular dysfunction: Metformin’s role in combating valproic acid-induced damage in rats

    Article • Reproductive Biology, December 2025, Elsevier

    Dr Ali S Abdelhameed

  6. Evaluation of Niraparib Metabolic Stability in Human Liver Microsomes Using Ultrafast UPLC‐MS/MS Technique: In Silico Screening for Structural Alerts Related to the Metabolic Lability and In Silico DEREK Toxicity

    Article • Biomedical Chromatography, November 2025, Wiley

    Dr Ali S Abdelhameed

  7. Cellular cAMP Content and Mitochondrial Profile Define Different Subtypes of Ovarian Cancer Cells

    Article • International Journal of Molecular Sciences, October 2025, MDPI AG

    Dr Ali S Abdelhameed

  8. Ultra-fast eco-friendly UHPLC–MS/MS methodology for the quantification of ASP3026 in human liver microsomes: Evaluation of metabolic stability via in silico software and in vitro metabolic incubation

    Article • Acta Chromatographica, October 2025, Akademiai Kiado

    Dr Ali S Abdelhameed

  9. Evaluation of Anlotinib Metabolic Stability in HLMs Matrix Applying Ultra‐Fast UPLC–MS/MS Approach: Greenness Assessment With In Silico Testing for Structural Alarms Related to the Metabolic Lability and DEREK Toxicity

    Article • Biomedical Chromatography, October 2025, Wiley

    Mohamed Attwa, Dr Ali S Abdelhameed

  10. Ultra‐Fast Green UPLC‐MS/MS Method for the Quantification of Cediranib in the Human Liver Microsome Matrix: In Vitro and In Silico Metabolic Stability Assessment

    Article • Archiv der Pharmazie, September 2025, Wiley

    Dr Ali S Abdelhameed

  11. Synthesis of a novel dual-functional Ti₃C₂ MXene-based composite for sustainable photocatalytic CO₂ conversion and pollutant degradation: Characterization and optimization of process parameters

    Article • Journal of Alloys and Compounds, September 2025, Elsevier

    Dr Ali S Abdelhameed

  12. An ultra-fast validated green UPLC-MS/MS approach for the evaluation of zanubrutinib in vitro metabolic stability in human liver microsomes: Screening for in silico metabolic lability, ADME parameters, and DEREK toxic alerts

    Article • Acta Chromatographica, August 2025, Akademiai Kiado

    Mohamed Attwa, Dr Ali S Abdelhameed

  13. Ziziphus spina-christi alleviates paracetamol-induced hepatorenal toxicity in rats through in vivo and computational approaches

    Article • Scientific Reports, August 2025, Springer Science + Business Media

    Dr Ali S Abdelhameed

  14. Generative artificial intelligence, integrative bioinformatics, and single-cell analysis reveal Alzheimer’s genetic and immune landscape

    Article • Molecular Therapy — Nucleic Acids, June 2025, Elsevier

    Dr Ali S Abdelhameed

  15. Recent SARS-CoV-2 evolution trajectories indicate the emergence of Omicron's several subvariants and the current rise of KP.3.1.1 and XEC

    Article • Virology, June 2025, Elsevier

    Dr Ali S Abdelhameed

  16. Deciphering the structural and dynamic effects of SHP2-E76 mutations: mechanistic insights into oncogenic activation

    Article • BMC Chemistry, May 2025, Springer Science + Business Media

    Dr Ali S Abdelhameed

  17. Boosting photocatalytic H2O2 production and non-biodegradable ofloxacin removal via a novel Ti3C2 MXene nanosheet-supported BiVO4/InVO4 Z-scheme heterojunction: Optimization and mechanism insights

    Article • Journal of Water Process Engineering, May 2025, Elsevier

    Dr Ali S Abdelhameed

  18. Engineering a novel BiVO4-CuFe2O4@MXene heterojunction with boosted photocatalytic activity: Visible-light-driven enrofloxacin degradation from polluted water and H2 production

    Article • Journal of Alloys and Compounds, May 2025, Elsevier

    Dr Ali S Abdelhameed

  19. A Computational Quest for Finding Novel Drug Targets against Mycobacterium tuberculosis

    Article • Indian Journal of Microbiology, April 2025, Springer Science + Business Media

    Dr Ali S Abdelhameed

  20. Activin-A urine levels correlate with radiological patterns in preterm infants complicated by intraventricular hemorrhage

    Article • Italian Journal of Pediatrics, March 2025, Springer Science + Business Media

    Dr Ali S Abdelhameed

  21. Cigarette Smoke and Heated Tobacco Product Exhibit Distinct Biochemical Pathways of Microglial Activation Under Hypoxia-Reoxygenation

    Article • March 2025, MDPI AG

    Dr Massimo Caruso, Dr Ali S Abdelhameed

  22. Validated and green UPLC-MS/MS method for belumosudil quantification in human liver microsomes: Application to in vitro metabolic stability assessment

    Article • Acta Chromatographica, March 2025, Akademiai Kiado

    Mohamed Attwa, Dr Ali S Abdelhameed

  23. Phylogenetic analyses of the spread of Clade I MPOX in African and non-African nations

    Article • Virus Genes, February 2025, Springer Science + Business Media

    Dr Ali S Abdelhameed

  24. Ejaculatory abstinence duration impacts semen parameters: Insights from a retrospective analysis in male infertility on 23,527 analyses

    Article • Frontiers in Endocrinology, February 2025, Frontiers

    Dr Ali S Abdelhameed

  25. Changes in adrenomedullin in bronchoalveolar lavage fluid with chorioamnionitis in a sheep-based model

    Article • The Journal of Maternal-Fetal & Neonatal Medicine, January 2025, Taylor & Francis

    Dr Ali S Abdelhameed

  26. Sensory Characteristics and Impact of Flavanol-Rich Grape and Blueberry Extract on Blood Flow Velocity and Oxidative Stress

    Article • Journal of Dietary Supplements, January 2025, Taylor & Francis

    Dr Ali S Abdelhameed

  27. An ultra-fast validated green UPLC-MS/MS method for the quantification of osimertinib in human liver microsomes: Screening for ADME parameters and in vitro metabolic stability

    Article • Acta Chromatographica, January 2025, Akademiai Kiado

    Mohamed Attwa, Dr Ali S Abdelhameed

  28. An ultra-fast UPLC-MS/MS approach for the quantification of baricitinib in the HLM matrix: greenness assessment with application to in vitro and in silico metabolic stability studies

    Article • Analytical Methods, January 2025, Royal Society of Chemistry

    Mohamed Attwa, Dr Ali S Abdelhameed

  29. An Ultrafast UPLC‐MS/MS Approach for Determining the In Vitro Metabolic Stability of Duvelisib in the HLMs: In Silico Screening for Metabolic Lability, ADME Features, and DEREK Alerts

    Article • International Journal of Analytical Chemistry, January 2025, Wiley

    Dr Ali S Abdelhameed

  30. Quercetin, Isoquercitrin, and Quercetin‐3‐Rutinoside: Understanding the Pharmacological, Organoleptic, ADME Properties, Human Health Toxicity, Ecological Risk, and Cosmetic Risk of Using Integrative Bioinformatics

    Article • Journal of Food Quality, January 2025, Wiley

    Dr Ali S Abdelhameed

  31. A comparative analysis of the impact of repeated administration of flavan 3-ol on brown, subcutaneous, and visceral adipose tissue

    Article • Open Medicine, January 2025, De Gruyter

    Dr Ali S Abdelhameed

  32. Assessment of the metabolic stability of avapritinib in human liver microsomes using a fast and green UPLC-MS/MS method: screening for structural alarms associated with metabolic lability and in silico tox...

    Article • Analytical Methods, January 2025, Royal Society of Chemistry

    Dr Ali S Abdelhameed

  33. Determination of veliparib metabolic stability in the human liver microsomes using a hydrophilic interaction UPLC-MS/MS quantitative method: greenness assessment with an in silico study for ADME, DEREK ala...

    Article • The Analyst, January 2025, Royal Society of Chemistry

    Dr Ali S Abdelhameed

  34. Development and validation of a quick and sensitive UPLC-MS/MS method for measuring ensartinib in HLMs: investigation of structural alerts associated with metabolic lability and in silico toxicity

    Article • The Analyst, January 2025, Royal Society of Chemistry

    Dr Ali S Abdelhameed

  35. Validated green ultra-fast UPLC-MS/MS method for the quantification of fedratinib in an HLM matrix: application to in vitro and in silico metabolic stability ...

    Article • Analytical Methods, January 2025, Royal Society of Chemistry

    Dr Ali S Abdelhameed

  36. Integrative approaches to m6A and m5C RNA modifications in autism spectrum disorder revealing potential causal variants

    Article • Mammalian Genome, December 2024, Springer Science + Business Media

    Dr Ali S Abdelhameed

  37. An immunohistochemical evaluation of fast twitch muscle formation induced by repeated administration of flavan 3‐ols in mice

    Article • The FASEB Journal, December 2024, Wiley

    Dr Ali S Abdelhameed

  38. An Ultra-Fast Validated Green UPLC-MS/MS Approach for Assessing Revumenib in Human Liver Microsomes: In Vitro Absorption, Distribution, Metabolism, and Excretion and Metabolic Stability Evaluation

    Article • Medicina, November 2024, MDPI AG

    Mohamed Attwa, Dr Ali S Abdelhameed

  39. Heavy Metal Nanoparticle Detection in Human and Formula Milk

    Article • Foods, October 2024, MDPI AG

    Dr Ali S Abdelhameed

  40. Change in Nfkb/Nrf2/Bax Levels by High Monomeric Polyphenols Berries Extract (HMPBE) in Acute and Chronic Secondary Brain Damage

    Article • Cellular Physiology and Biochemistry, October 2024, Cell Physiol Biochem Press GmbH and Co KG

    Dr Ali S Abdelhameed

  41. An Ultra-Fast Green UHPLC-MS/MS Method for Assessing the In Vitro Metabolic Stability of Dovitinib: In Silico Study for Absorption, Distribution, Metabolism, Excretion, Metabolic Lability, and DEREK Alerts

    Article • Medicina, October 2024, MDPI AG

    Mohamed Attwa, Dr Ali S Abdelhameed

  42. Redox Modulation of Meniere Disease by Coriolus versicolor Treatment, a Nutritional Mushroom Approach with Neuroprotective Potential

    Article • Current Neuropharmacology, October 2024, Bentham Science Publishers

    Dr Ali S Abdelhameed

  43. Assessment of the in vitro metabolic stability of CEP-37440, a selective FAK/ALK inhibitor, in HLMs using fast UPLC–MS/MS method: in silico metabolic lability and DEREK alerts screening

    Article • Frontiers in Chemistry, September 2024, Frontiers

    Mohamed Attwa, Dr Ali S Abdelhameed

  44. Unraveling the enigma: Probing the unconventional binding site and binding mechanism of entrectinib with human serum albumin through spectroscopic, molecular docking, and dynamic simulation analyses

    Article • Journal of Molecular Liquids, September 2024, Elsevier

    Dr Ali S Abdelhameed

  45. Capillary blood parameters are gestational age, birthweight, delivery mode and gender dependent in healthy preterm and term infants

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), August 2024, De Gruyter

    Dr Ali S Abdelhameed

  46. Presepsin in Human Milk Is Delivery Mode and Gender Dependent

    Article • Nutrients, August 2024, MDPI AG

    Dr Ali S Abdelhameed

  47. An ultra‐fast green ultra‐high‐performance liquid chromatography‐tandem mass spectrometry method for estimating the in vitro metabolic stability of zotizalkib in human liver microsomes

    Article • Journal of Separation Science, August 2024, Wiley

    Mohamed Attwa, Dr Ali S Abdelhameed

  48. An ultra‐fast ultra‐high‐performance liquid chromatography‐tandem mass spectrometry method for estimating the in vitro metabolic stability of palbociclib in human liver microsomes: In silico study for metabolic lability, absorption, distribution, metab...

    Article • Journal of Separation Science, August 2024, Wiley

    Mohamed Attwa, Dr Ali S Abdelhameed

  49. Transgenerational hormesis in healthy aging and antiaging medicine from bench to clinics: Role of food components

    Article • Mechanisms of Ageing and Development, August 2024, Elsevier

    Dr Ali S Abdelhameed

  50. Characterization of the in vitro metabolic profile of nazartinib in HLMs using UPLC-MS/MS method: In silico metabolic lability and DEREK structural alerts screening using StarDrop software

    Article • Heliyon, July 2024, Elsevier

    Mohamed Attwa, Dr Ali S Abdelhameed

  51. Ultra-fast UPLC–MS/MS approach for estimating X-376 in human liver microsomes: Evaluation of metabolic stability via in silico software and in vitro analysis

    Article • Journal of Pharmacological and Toxicological Methods, July 2024, Elsevier

    Mohamed Attwa, Dr Ali S Abdelhameed

  52. Effects of long and short ejaculatory abstinence on sperm parameters: a meta-analysis of randomized-controlled trials

    Article • Frontiers in Endocrinology, May 2024, Frontiers

    Dr Ali S Abdelhameed

  53. CYP7B1 as a Biomarker for Prostate Cancer Risk and Progression: Metabolic and Oncogenic Signatures (Diagnostic Immunohistochemistry Analysis by Tissue Microarray in Prostate Cancer Patients—Diamond Study)

    Article • International Journal of Molecular Sciences, April 2024, MDPI AG

    Professor Antonio Rescifina, Dr Ali S Abdelhameed

  54. Phase angle at bioelectric impedance analysis is associated with detrimental sperm quality in idiopathic male infertility: a preliminary clinical study

    Article • Frontiers in Endocrinology, April 2024, Frontiers

    Dr Ali S Abdelhameed

  55. Sensory Properties, Redox Characteristics, and Impact on the Hemodynamics of the Flavanol-Rich Fraction Originated Grape and Blueberry

    Article • March 2024, MDPI AG

    Salvatore Cuzzocrea, Dr Ali S Abdelhameed

  56. Microglia and glioblastoma heterocellular interplay sustains tumour growth and proliferation as an off‐target effect of radiotherapy

    Article • Cell Proliferation, March 2024, Wiley

    Professor Nunzio Vicario, Dr Ali S Abdelhameed

  57. REDOXOMICS IN AGEING AND NEURODEGENERATIVE DISORDERS: FROM BENCH TO CLINICS

    Article • Translational Medicine UniSa, January 2024, Translational Medicine, University of Salerno

    Dr Ali S Abdelhameed

  58. Autophagy machinery plays an essential role in traumatic brain injury-induced apoptosis and its related behavioral abnormalities in mice: focus on Boswellia Sacra gum resin

    Article • Frontiers in Physiology, January 2024, Frontiers

    Dr Ali S Abdelhameed

  59. Ion Trap LC/MS reveals the generation of reactive intermediates in acalabrutinib metabolism: phase I metabolic profiling and bioactivation pathways elucidation

    Article • RSC Advances, January 2024, Royal Society of Chemistry

    Mohamed Attwa, Dr Ali S Abdelhameed

  60. Frankincense: A neuronutrient to approach Parkinson’s disease treatment

    Article • Open Medicine, January 2024, De Gruyter

    Dr Ali S Abdelhameed

  61. Corrigendum to “Frankincense: A neuronutrient to approach Parkinson’s disease treatment”

    Article • Open Medicine, January 2024, De Gruyter

    Dr Ali S Abdelhameed

  62. Ponatinib: A comprehensive drug profile

    Article • January 2024, Elsevier

    Dr Ali S Abdelhameed

  63. Polyphenols in Inner Ear Neurobiology, Health and Disease: From Bench to Clinics

    Article • Medicina, November 2023, MDPI AG

    Dr Ali S Abdelhameed

  64. Hormesis defines the limits of lifespan

    Article • Ageing Research Reviews, November 2023, Elsevier

    Dr Ali S Abdelhameed

  65. An Ultrafast UPLC–MS/MS Method for Characterizing the In Vitro Metabolic Stability of Acalabrutinib

    Article • Molecules, October 2023, MDPI AG

    Mohamed Attwa, Dr Ali S Abdelhameed

  66. A Sensitive, Green, and Fast LC–MS/MS Analytical Method for the Quantification of Ribociclib: Evaluation of the Metabolic Stability in HLMs

    Article • Separations, August 2023, MDPI AG

    Mohamed Attwa, Dr Ali S Abdelhameed

  67. A Fast LC-MS/MS Methodology for Estimating Savolitinib in Human Liver Microsomes: Assessment of Metabolic Stability Using In Vitro Metabolic Incubation and In Silico Software Analysis

    Article • Separations, August 2023, MDPI AG

    Mohamed Attwa, Dr Ali S Abdelhameed

  68. Binding of Novobiocin Paves the Way for Inhibition of DEAH-box Helicase 8

    Article • Indian Journal of Pharmaceutical Education and Research, June 2023, EManuscript Services

    Dr Mohammad Ayaz Ahmad, Dr Ali S Abdelhameed

  69. Synthesis, Molecular Docking, c-Met Inhibitions of 2,2,2-Trichloroethylidene- cyclohexane-1, 3-dione Derivatives Together with their Application as Target SARS-CoV-2 main Protease (Mpro) and as Potential anti-COVID-19

    Article • Combinatorial Chemistry & High Throughput Screening, June 2023, Bentham Science Publishers

    Dr Ali S Abdelhameed, Mahmoud Mahmoud

  70. Reactive intermediates formation and bioactivation pathways of spebrutinib revealed by LC-MS/MS: In vitro and in silico metabolic study

    Article • Heliyon, June 2023, Elsevier

    Mohamed Attwa, Dr Ali S Abdelhameed

  71. Investigation of Fenebrutinib Metabolism and Bioactivation Using MS3 Methodology in Ion Trap LC/MS

    Article • Molecules, May 2023, MDPI AG

    Mohamed Attwa, Dr Ali S Abdelhameed

  72. Development of a Fast and Sensitive UPLC–MS/MS Analytical Methodology for Fenebrutinib Estimation in Human Liver Microsomes: In Vitro and In Silico Metabolic Stability Evaluation

    Article • Separations, May 2023, MDPI AG

    Mohamed Attwa, Dr Ali S Abdelhameed

  73. An UPLC–ESI–MS/MS Bioanalytical Methodology for the Quantification of Gilteritinib in Human Liver Microsomes: Application to In Vitro and In Silico Metabolic Stability Estimation

    Article • Separations, April 2023, MDPI AG

    Mohamed Attwa, Dr Ali S Abdelhameed

  74. A Rapid and Sensitive UPLC-MS/MS Method for Quantifying Capmatinib in Human Liver Microsomes: Evaluation of Metabolic Stability by In Silico and In Vitro Analysis

    Article • Separations, April 2023, MDPI AG

    Mohamed Attwa, Dr Ali S Abdelhameed

  75. MemophenolTM Prevents Amyloid-β Deposition and Attenuates Inflammation and Oxidative Stress in the Brain of an Alzheimer’s Disease Rat

    Article • International Journal of Molecular Sciences, April 2023, MDPI AG

    Salvatore Cuzzocrea, Dr Ali S Abdelhameed

  76. Mechanism of Action of Natural Compounds in Peripheral Multiorgan Dysfunction and Hippocampal Neuroinflammation Induced by Sepsis

    Article • Antioxidants, March 2023, MDPI AG

    Salvatore Cuzzocrea, Dr Ali S Abdelhameed

  77. Spectroscopic and computational investigation of the interaction between the new anticancer agent enasidenib and human serum albumin

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, April 2022, Elsevier

    Dr Ali S Abdelhameed

  78. Estimation of zorifertinib metabolic stability in human liver microsomes using LC–MS/MS

    Article • Journal of Pharmaceutical and Biomedical Analysis, March 2022, Elsevier

    Mohamed Attwa, Dr Ali S Abdelhameed

  79. A validated LC-MS/MS analytical method for the quantification of pemigatinib: metabolic stability evaluation in human liver microsomes

    Article • RSC Advances, January 2022, Royal Society of Chemistry

    Mohamed Attwa, Dr Ali S Abdelhameed

  80. Development of novel univariate and multivariate validated chemometric methods for the analysis of dasatinib, sorafenib, and vandetanib in pure form, dosage forms and biological fluids

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, January 2022, Elsevier

    Mohamed Attwa, Dr Ali S Abdelhameed

  81. Spectroscopic, molecular docking and dynamic simulation studies of binding between the new anticancer agent olmutinib and human serum albumin

    Article • Journal of Biomolecular Structure and Dynamics, November 2021, Taylor & Francis

    Mohamed Attwa, Dr Ali S Abdelhameed

  82. Simple and efficient spectroscopic-based univariate sequential methods for simultaneous quantitative analysis of vandetanib, dasatinib, and sorafenib in pharmaceutical preparations and biological fluids

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, November 2021, Elsevier

    Mohamed Attwa, Dr Ali S Abdelhameed

  83. LC–MS/MS Estimation of Rociletinib Levels in Human Liver Microsomes: Application to Metabolic Stability Estimation

    Article • Drug Design Development and Therapy, September 2021, Taylor & Francis

    Dr Ali S Abdelhameed

  84. Synthesis of Novel Halogenated Heterocyclic compounds and their uses as Target SARS-CoV-2 main Protease (Mpro) and Potential Anti-Covid-19

    Article • March 2021, Springer Science + Business Media

    Dr Ali S Abdelhameed

  85. <p>Characterization of Stable and Reactive Metabolites of the Anticancer Drug, Ensartinib, in Human Liver Microsomes Using LC-MS/MS: An in silico and Practical Bioactivation Approach</p>

    Article • Drug Design Development and Therapy, November 2020, Taylor & Francis

    Mohamed Attwa, Dr Ali S Abdelhameed

  86. Identification of Iminium Intermediates Generation in the Metabolism of Tepotinib Using LC-MS/MS: In Silico and Practical Approaches to Bioactivation Pathway Elucidation

    Article • Molecules, October 2020, MDPI AG

    Mohamed Attwa, Dr Ali S Abdelhameed

  87. <p>LC-MS/MS Estimation of the Anti-Cancer Agent Tandutinib Levels in Human Liver Microsomes: Metabolic Stability Evaluation Assay</p>

    Article • Drug Design Development and Therapy, October 2020, Taylor & Francis

    Mohamed Attwa, Dr Ali S Abdelhameed

  88. Biophysical Insight into the Interaction of Human Lysozyme with Anticancer Drug Anastrozole: A Multitechnique Approach

    Article • The Scientific World JOURNAL, August 2020, Hindawi Publishing Corporation

    Professor Rizwan Hasan Khan, Dr Mohammad Rehan Ajmal Khan, Dr Ali S Abdelhameed

  89. Corrigendum to “Investigating the site selective binding of busulfan to human serum albumin: Biophysical and molecular docking approaches” [Int. J. Biol. Macromol. 107 (2018) 1414–1421]

    Article • International Journal of Biological Macromolecules, August 2020, Elsevier

    Dr Mohammad Rehan Ajmal Khan, Dr Ali S Abdelhameed

  90. Corrigendum to “Deciphering the enhanced inhibitory, disaggregating and cytoprotective potential of promethazine towards amyloid fibrillation.” [Int. J. Biol. Macromol. 106 (2018) 851–863]

    Article • International Journal of Biological Macromolecules, August 2020, Elsevier

    Dr Ali S Abdelhameed

  91. Biophysical insight into the interaction of levocabastine with human serum albumin: spectroscopy and molecular docking approach

    Article • Journal of Biomolecular Structure and Dynamics, April 2020, Taylor & Francis

    Professor Rizwan Hasan Khan, Dr Mohammad Rehan Ajmal Khan, Dr Ali S Abdelhameed

  92. <p>Metabolic Stability Assessment of New PARP Inhibitor Talazoparib Using Validated LC–MS/MS Methodology: In silico Metabolic Vulnerability and Toxicity Studies</p>

    Article • Drug Design Development and Therapy, February 2020, Taylor & Francis

    Mohamed Attwa, Dr Ali S Abdelhameed

  93. Phase I metabolic profiling and unexpected reactive metabolites in human liver microsome incubations of X-376 using LC-MS/MS: bioactivation pathway elucidation andin silicotoxicity studies of its metabolites

    Article • RSC Advances, January 2020, Royal Society of Chemistry

    Mohamed Attwa, Dr Ali S Abdelhameed

  94. Spectroscopic and molecular docking studies reveal binding characteristics of nazartinib (EGF816) to human serum albumin

    Article • Royal Society Open Science, January 2020, Royal Society Publishing

    Dr Ali S Abdelhameed

  95. Azilsartan medoxomil

    Article • January 2020, Elsevier

    Dr Ali S Abdelhameed

  96. Emtricitabine

    Article • January 2020, Elsevier

    Dr Ali S Abdelhameed

  97. Detection and characterization of olmutinib reactive metabolites by LC–MS/MS: Elucidation of bioactivation pathways

    Article • Journal of Separation Science, December 2019, Wiley

    Mohamed Attwa, Dr Ali S Abdelhameed

  98. Potent Activity of a Novel Vanadyl (IV)-Vitamin D3 Complex Against Streptozotocin-Induced Diabetes in Rats: Synthesis, Characterization and Biological Assessments

    Article • Journal of Biobased Materials and Bioenergy, December 2019, American Scientific Publishers

    Dr Ali S Abdelhameed

  99. Structural, spectroscopic, Hirshfeld surface and charge distribution analysis of 3-(1H-imidazole-1-yl)-1-phenylpropan-1-ol complemented by molecular docking predictions: An integrated experimental and computational approach

    Article • Journal of Molecular Structure, November 2019, Elsevier

    Dr Ali S Abdelhameed

  100. Antiproliferative activity and possible mechanism of action of certain 5-methoxyindole tethered C-5 functionalized isatins

    Article • Drug Design Development and Therapy, August 2019, Taylor & Francis

    Dr Ali S Abdelhameed

  101. Liquid chromatography–tandem mass spectrometry metabolic profiling of nazartinib reveals the formation of unexpected reactive metabolites

    Article • Royal Society Open Science, August 2019, Royal Society Publishing

    Mohamed Attwa, Dr Ali S Abdelhameed

  102. A highly sensitive LC-MS/MS method to determine novel Bruton's tyrosine kinase inhibitor spebrutinib: application to metabolic stability evaluation

    Article • Royal Society Open Science, June 2019, Royal Society Publishing

    Mohamed Attwa, Dr Ali S Abdelhameed

  103. Validated LC-MS/MS assay for quantification of the newly approved tyrosine kinase inhibitor, dacomitinib, and application to investigating its metabolic stability

    Article • PLOS One, April 2019, PLOS

    Dr Ali S Abdelhameed, Mohamed Attwa

  104. Novel BTK inhibitor acalabrutinib (ACP-196) tightly binds to site I of the human serum albumin as observed by spectroscopic and computational studies

    Article • International Journal of Biological Macromolecules, April 2019, Elsevier

    Dr Ali S Abdelhameed

  105. Reactive intermediates and bioactivation pathways characterization of avitinib by LC–MS/MS: In vitro metabolic investigation

    Article • Journal of Pharmaceutical and Biomedical Analysis, February 2019, Elsevier

    Mohamed Attwa, Dr Ali S Abdelhameed

  106. A simple liquid chromatography-tandem mass spectrometry method to accurately determine the novel third-generation EGFR-TKI naquotinib with its applicability to metabolic stability assessment

    Article • RSC Advances, January 2019, Royal Society of Chemistry

    Mohamed Attwa, Dr Ali S Abdelhameed

  107. Reactive intermediates in copanlisib metabolism identified by LC-MS/MS: phase I metabolic profiling

    Article • RSC Advances, January 2019, Royal Society of Chemistry

    Mohamed Attwa, Dr Ali S Abdelhameed

  108. Molecular interactions of AL3818 (anlotinib) to human serum albumin as revealed by spectroscopic and molecular docking studies

    Article • Journal of Molecular Liquids, January 2019, Elsevier

    Dr Ali S Abdelhameed

  109. Spectroscopic and molecular docking studies of the binding of the angiotensin II receptor blockers (ARBs) azilsartan, eprosartan and olmesartan to bovine serum albumin

    Article • Journal of Luminescence, November 2018, Elsevier

    Dr Ali S Abdelhameed

  110. Synthesis, Spectroscopic Identification and Molecular Docking of Certain N-(2-{[2-(1H-Indol-2-ylcarbonyl)hydrazinyl](oxo)acetyl}phenyl)acetamides and N-[2-(2-{[2-(Acetylamino)phenyl](oxo)acetyl}hydrazinyl)-2-oxoethyl]-1H-indole-2-carboxamides: New Anti...

    Article • Molecules, April 2018, MDPI AG

    Dr Ali S Abdelhameed

  111. Interaction of catecholamine precursor l-Dopa with lysozyme: A biophysical insight

    Article • International Journal of Biological Macromolecules, April 2018, Elsevier

    Professor Rizwan Hasan Khan, Dr Mohammad Rehan Ajmal Khan, Dr Ali S Abdelhameed

  112. Investigating the site selective binding of busulfan to human serum albumin: Biophysical and molecular docking approaches

    Article • International Journal of Biological Macromolecules, February 2018, Elsevier

    Professor Rizwan Hasan Khan, Dr Mohammad Rehan Ajmal Khan, Dr Ali S Abdelhameed

  113. Unraveling the binding characteristics of the anti-HIV agents abacavir, efavirenz and emtricitabine to bovine serum albumin using spectroscopic and molecular simulation approaches

    Article • Journal of Molecular Liquids, February 2018, Elsevier

    Dr Ali S Abdelhameed

  114. Deciphering the enhanced inhibitory, disaggregating and cytoprotective potential of promethazine towards amyloid fibrillation

    Article • International Journal of Biological Macromolecules, January 2018, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  115. Characterization of reactive intermediates formation in dacomitinib metabolism and bioactivation pathways elucidation by LC-MS/MS: in vitro phase I metabolic investigation

    Article • RSC Advances, January 2018, Royal Society of Chemistry

    Mohamed Attwa, Dr Ali S Abdelhameed

  116. Investigation of the metabolic stability of olmutinib by validated LC-MS/MS: quantification in human plasma

    Article • RSC Advances, January 2018, Royal Society of Chemistry

    Mohamed Attwa, Dr Ali S Abdelhameed

  117. Probing the interaction of cephalosporin antibiotic–ceftazidime with human serum albumin: A biophysical investigation

    Article • International Journal of Biological Macromolecules, December 2017, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan, Dr Mohammad Rehan Ajmal Khan

  118. Biophysical and In Silico Studies of the Interaction between the Anti-Viral Agents Acyclovir and Penciclovir, and Human Serum Albumin

    Article • Molecules, November 2017, MDPI AG

    Dr Ali S Abdelhameed

  119. Cationic surfactant mediated fibrillogenesis in bovine liver catalase: a biophysical approach

    Article • Journal of Biomolecular Structure and Dynamics, August 2017, Taylor & Francis

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan, Dr Mohammad Rehan Ajmal Khan

  120. Isatin-benzoazine molecular hybrids as potential antiproliferative agents: synthesis and in vitro pharmacological profiling

    Article • Drug Design Development and Therapy, August 2017, Dove Medical Press

    Dr Ali S Abdelhameed, Mohamed Attwa, Wagdy Eldehna

  121. Exploring the interaction forces involved in the binding of the multiple myeloma drug lenalidomide to bovine serum albumin

    Article • Journal of Molecular Liquids, July 2017, Elsevier

    Dr Ali S Abdelhameed

  122. Synthesis and Biophysical Insights into the Binding of a Potent Anti-Proliferative Non-symmetric Bis-isatin Derivative with Bovine Serum Albumin: Spectroscopic and Molecular Docking Approaches

    Article • Applied Sciences, June 2017, MDPI AG

    Dr Ali S Abdelhameed, Wagdy Eldehna

  123. Anti-Parkinsonian L-Dopa can also act as anti-systemic amyloidosis—A mechanistic exploration

    Article • International Journal of Biological Macromolecules, June 2017, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan, Dr Mohammad Rehan Ajmal Khan

  124. Ascorbic acid inhibits human insulin aggregation and protects against amyloid induced cytotoxicity

    Article • Archives of Biochemistry and Biophysics, May 2017, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan, Dr Mohammad Rehan Ajmal Khan

  125. Biophysical insight reveals tannic acid as amyloid inducer and conformation transformer from amorphous to amyloid aggregates in Concanavalin A (ConA)

    Article • Journal of Biomolecular Structure and Dynamics, April 2017, Taylor & Francis

    Dr Ali S Abdelhameed, Rizwan KHAN, Professor Rizwan Hasan Khan, Tajalli Ilm Chandel , Dr Mohammad Rehan Ajmal Khan

  126. A multitechnique approach to probe the interaction of a therapeutic tyrosine kinase inhibitor nintedanib and bovine serum albumin

    Article • Preparative Biochemistry & Biotechnology, February 2017, Taylor & Francis

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  127. Liquid chromatographic-tandem mass spectrometric assay for simultaneous quantitation of tofacitinib, cabozantinib and afatinib in human plasma and urine

    Article • Tropical Journal of Pharmaceutical Research, January 2017, African Journals Online (AJOL)

    Dr Ali S Abdelhameed, Mohamed Attwa

  128. Fluorescence spectroscopic and molecular docking studies of the binding interaction between the new anaplastic lymphoma kinase inhibitor crizotinib and bovine serum albumin

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, January 2017, Elsevier

    Dr Ali S Abdelhameed

  129. Polyols (Glycerol and Ethylene glycol) mediated amorphous aggregate inhibition and secondary structure restoration of metalloproteinase-conalbumin (ovotransferrin)

    Article • International Journal of Biological Macromolecules, January 2017, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  130. A biophysical and computational study unraveling the molecular interaction mechanism of a new Janus kinase inhibitor Tofacitinib with bovine serum albumin

    Article • Journal of Molecular Recognition, December 2016, Wiley

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan, Dr Mohammad Rehan Ajmal Khan

  131. Mechanisms of protein misfolding: Novel therapeutic approaches to protein-misfolding diseases

    Article • Journal of Molecular Structure, November 2016, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  132. Solution conformation and flexibility of capsular polysaccharides from Neisseria meningitidis and glycoconjugates with the tetanus toxoid protein

    Article • Scientific Reports, October 2016, Nature

    Dr Ali S Abdelhameed

  133. Correction: A Comprehensive Spectroscopic and Computational Investigation to Probe the Interaction of Antineoplastic Drug Nordihydroguaiaretic Acid with Serum Albumins

    Article • PLOS One, October 2016, PLOS

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan, Dr Mohammad Rehan Ajmal Khan

  134. An LC-MS/MS method for rapid and sensitive high-throughput simultaneous determination of various protein kinase inhibitors in human plasma

    Article • Biomedical Chromatography, August 2016, Wiley

    Dr Ali S Abdelhameed, Mohamed Attwa

  135. Liquid chromatographic-mass spectrometric method for determination of drug content uniformity of two commonly used dermatology medications in a split-tablet dosage form

    Article • Tropical Journal of Pharmaceutical Research, July 2016, African Journals Online (AJOL)

    Dr Ali S Abdelhameed, Mohamed Attwa

  136. A Comprehensive Spectroscopic and Computational Investigation to Probe the Interaction of Antineoplastic Drug Nordihydroguaiaretic Acid with Serum Albumins

    Article • PLOS One, July 2016, PLOS

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan, Dr Mohammad Rehan Ajmal Khan

  137. Interaction of the recently approved anticancer drug nintedanib with human acute phase reactant α 1-acid glycoprotein

    Article • Journal of Molecular Structure, July 2016, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan, Dr Mohammad Rehan Ajmal Khan

  138. A novel method to determine new potent angiotensin inhibitor, azilsartan, in human plasma via micelle-enhanced spectrofluorimetry using cremophor RH 40

    Article • Tropical Journal of Pharmaceutical Research, May 2016, African Journals Online (AJOL)

    Dr Ali S Abdelhameed

  139. Binding of Janus kinase inhibitor tofacitinib with human serum albumin: multi-technique approach

    Article • Journal of Biomolecular Structure and Dynamics, May 2016, Taylor & Francis

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  140. Structure of amyloid oligomers and their mechanisms of toxicities: Targeting amyloid oligomers using novel therapeutic approaches

    Article • European Journal of Medicinal Chemistry, May 2016, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  141. ChemInform Abstract: Structure of Amyloid Oligomers and Their Mechanisms of Toxicities: Targeting Amyloid Oligomers Using Novel Therapeutic Approaches

    Article • ChemInform, May 2016, Wiley

    Dr Ali S Abdelhameed

  142. Interplay of multiple interaction forces: Binding of tyrosine kinase inhibitor nintedanib with human serum albumin

    Article • Journal of Photochemistry and Photobiology B Biology, April 2016, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  143. Interaction of new kinase inhibitors cabozantinib and tofacitinib with human serum alpha-1 acid glycoprotein. A comprehensive spectroscopic and molecular Docking approach

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, April 2016, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan, Dr Mohammad Rehan Ajmal Khan

  144. A glycoconjugate of Haemophilus influenzae Type b capsular polysaccharide with tetanus toxoid protein: hydrodynamic properties mainly influenced by the carbohydrate

    Article • Scientific Reports, February 2016, Nature

    Dr Ali S Abdelhameed

  145. A highly efficient and sensitive LC-MS/MS method for the determination of afatinib in human plasma: application to a metabolic stability study

    Article • Biomedical Chromatography, January 2016, Wiley

    Dr Ali S Abdelhameed, Mohamed Attwa

  146. A Spectroscopic Approach to Investigate the Molecular Interactions between the Newly Approved Irreversible ErbB blocker "Afatinib" and Bovine Serum Albumin

    Article • PLOS One, January 2016, PLOS

    Dr Ali S Abdelhameed

  147. Simultaneous quantitative analysis of olmesartan, amlodipine and hydrochlorothiazide in their combined dosage form utilizing classical and alternating least squares based chemometric methods

    Article • Acta Pharmaceutica, January 2016, De Gruyter

    Dr Ali S Abdelhameed

  148. Effect of galactose on acid induced molten globule state of Soybean Agglutinin: Biophysical approach

    Article • Journal of Molecular Structure, November 2015, Elsevier

    Dr Ali S Abdelhameed, Professor Rizwan Hasan Khan

  149. Experimental and Theoretical Studies of the Vibrational and Electronic Properties of (2E)-2-[3-(1H-imidazol-1-yl)-1-phenyl-propylidene]-N-phenylhydrazinecarboxamide: An Anticonvulsant Agent

    Article • Applied Sciences, October 2015, MDPI AG

    Dr Ali S Abdelhameed

  150. Erratum to: Biophysical Interactions of Novel Oleic Acid Conjugate and its Anticancer Potential in HeLa Cells

    Article • Journal of Fluorescence, March 2015, Springer Science + Business Media

    Dr Ali S Abdelhameed

  151. Biophysical Interactions of Novel Oleic Acid Conjugate and its Anticancer Potential in HeLa Cells

    Article • Journal of Fluorescence, February 2015, Springer Science + Business Media

    Dr Ali S Abdelhameed

  152. A new method to determine the new C-Met inhibitor “Cabozantinib” in dosage form and human plasma via micelle-enhanced spectrofluorimetry

    Article • RSC Advances, January 2015, Royal Society of Chemistry

    Dr Ali S Abdelhameed

  153. Spectrofluorimetric study of finasteride and bovine serum albumin interaction and its application for quantitative determination of finasteride in tablet dosage form

    Article • Analytical Methods, January 2015, Royal Society of Chemistry

    Dr Ali S Abdelhameed

  154. Nanosuspension: An Emerging Trend for Bioavailability Enhancement of Etodolac

    Article • International Journal of Polymer Science, January 2015, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed

  155. Insight into the Interaction between the HIV-1 Integrase Inhibitor Elvitegravir and Bovine Serum Albumin: A Spectroscopic Study

    Article • Journal of Spectroscopy, January 2015, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed

  156. Characterization of Capsular Polysaccharides and Their Glycoconjugates by Hydrodynamic Methods

    Article • January 2015, Springer Science + Business Media

    Dr Ali S Abdelhameed

  157. Micellar Enhanced Spectrofluorimetric Method for the Determination of Ponatinib in Human Plasma and Urine via Cremophor RH 40 as Sensing Agent

    Article • International Journal of Analytical Chemistry, January 2015, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed

  158. HPLC method with monolithic column for simultaneous determination of irbesartan and hydrochlorothiazide in tablets

    Article • Acta Pharmaceutica, June 2014, De Gruyter

    Dr Ali S Abdelhameed

  159. A Validated HPLC-DAD Method for Simultaneous Determination of Etodolac and Pantoprazole in Rat Plasma

    Article • Journal of Chemistry, January 2014, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed

  160. Pseudo-MS3Approach Using Electrospray Mass Spectrometry (ESI-MS/MS) to Characterize Certain (2E)-2-[3-(1H-Imidazol-1-yl)-1-phenylpropylidene]hydrazinecarboxamide Derivatives

    Article • Journal of Chemistry, January 2014, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed, Mohamed Attwa

  161. A Stability-Indicating HPLC-DAD Method for Determination of Stiripentol: Development, Validation, Kinetics, Structure Elucidation and Application to Commercial Dosage Form

    Article • Journal of Analytical Methods in Chemistry, January 2014, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed

  162. Multistage Fragmentation of Ion Trap Mass Spectrometry System and Pseudo-MS3of Triple Quadrupole Mass Spectrometry Characterize Certain (E)-3-(Dimethylamino)-1-arylprop-2-en-1-ones: A Comparative Study

    Article • The Scientific World JOURNAL, January 2014, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed, Mohamed Attwa

  163. Characterization and Anticancer Potential of Newly Synthesized Propofol Conjugates

    Article • Asian Journal of Chemistry, January 2014, Asian Journal of Chemistry

    Dr Ali S Abdelhameed

  164. Induced in-source fragmentation pattern of certain novel (1Z,2E)-N-(aryl)propanehydrazonoyl chlorides by electrospray mass spectrometry (ESI-MS/MS)

    Article • Chemistry Central Journal, January 2013, Springer Science + Business Media

    Dr Ali S Abdelhameed, Mohamed Attwa

  165. Comparative ANNs with Different Input Layers and GA-PLS Study for Simultaneous Spectrofluorimetric Determination of Melatonin and Pyridoxine HCl in the Presence of Melatonin’s Main Impurity

    Article • Molecules, January 2013, MDPI AG

    Dr Ali S Abdelhameed

  166. High Throughput Quantitative Bioanalytical LC/MS/MS Determination of Gemifloxacin in Human Urine

    Article • Journal of Chemistry, January 2013, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed, Mohamed Attwa

  167. An asymmetric and slightly dimerized structure for the tetanus toxoid protein used in glycoconjugate vaccines

    Article • Carbohydrate Polymers, November 2012, Elsevier

    Dr Gordon A. Morris, Dr Ali S Abdelhameed

  168. Solution properties of capsular polysaccharides from Streptococcus pneumoniae

    Article • Carbohydrate Polymers, September 2012, Elsevier

    Dr Gordon A. Morris, Dr Ali S Abdelhameed

  169. Extended Fujita approach to the molecular weight distribution of polysaccharides and other polymeric systems

    Article • Methods, May 2011, Elsevier

    Dr Gordon A. Morris, Dr Ali S Abdelhameed

  170. On the hydrodynamic analysis of conformation in mixed biopolymer systems

    Article • Polymer International, October 2010, Wiley

    Dr Gordon A. Morris, Dr Ali S Abdelhameed

  171. Molecular Weight Distribution Evaluation of Polysaccharides and Glycoconjugates Using Analytical Ultracentrifugation

    Article • Macromolecular Bioscience, July 2010, Wiley

    Dr Gordon A. Morris, Dr Ali S Abdelhameed

  172. An analytical ultracentrifuge study on ternary mixtures of konjac glucomannan supplemented with sodium alginate and xanthan gum

    Article • Carbohydrate Polymers, May 2010, Elsevier

    Dr Gordon A. Morris, Dr Ali S Abdelhameed

  173. A novel global hydrodynamic analysis of the molecular flexibility of the dietary fibre polysaccharide konjac glucomannan

    Article • Food Hydrocolloids, October 2009, Elsevier

    Dr Gordon A. Morris, Dr Ali S Abdelhameed