All Stories

  1. PARP1 rewires neuroinflammatory and redox metabolism associated with reactive neuroglia in neuropathic pain

    Article • Redox Biology, September 2026, Elsevier

    Rosalba Parenti, Professor Nunzio Vicario

  2. Long-Read RNA Sequencing Reveals an Isoform Switching Pattern in Healthy Microglial Cell Lines Exposed to Radiotherapy

    Article • Non-Coding RNA, August 2026, MDPI AG

    Professor Nunzio Vicario

  3. Glutamate accumulation in myelofibrosis microenvironment rewires mesenchymal stromal cells metabolic and epigenetic profiles

    Article • Cell Communication and Signaling, July 2026, Springer Science + Business Media

    Professor Nunzio Vicario

  4. Connexin Regulation and Modulation of Neural Stem Cell Differentiation Induced by Cell‐Permeable Itaconate

    Article • Journal of Cellular Physiology, May 2026, Wiley

    Professor Nunzio Vicario

  5. Retinal alterations resemble brain pathology in a rat model of Parkinson’s disease induced by intranigral infusion of α-synuclein oligomers

    Article • Cell Death Discovery, November 2025, Springer Science + Business Media

    Professor Nunzio Vicario

  6. Mitochondrial connexin 43 modulates metabolic stress adaptation in glioma cell lines

    Article • Cell Communication and Signaling, November 2025, Springer Science + Business Media

    Professor Nunzio Vicario

  7. GAP JUNCTIONS, HEMICHANNELS AND CONNEXINS AND THEIR ROLE IN THE NEUROVASCULAR UNIT

    Article • EuroMediterranean Biomedical Journal, October 2025, PAGEPress Publications

    Professor Nunzio Vicario

  8. Connexin 43 Role in Mitochondrial Transfer and Homeostasis in the Central Nervous System

    Article • Journal of Cellular Physiology, August 2025, Wiley

    Professor Nunzio Vicario

  9. Purine metabolism rewiring improves glioblastoma susceptibility to temozolomide treatment

    Article • Cell Death and Disease, April 2025, Springer Science + Business Media

    Professor Nunzio Vicario

  10. Mechanistic insights into connexin-mediated neuroglia crosstalk in neurodegenerative diseases

    Article • Frontiers in Cellular Neuroscience, February 2025, Frontiers

    Professor Nunzio Vicario

  11. Physiopathological effects of entrance versus distal spread-out Bragg peak on mouse spinal cord neurons

    Article • Scientific Reports, January 2025, Springer Science + Business Media

    Professor Nunzio Vicario

  12. Comparative evaluation of cigarette smoke and a heated tobacco product on microglial toxicity, oxidative stress and inflammatory response

    Article • Journal of Translational Medicine, September 2024, Springer Science + Business Media

    Professor Nunzio Vicario, Dr Massimo Caruso

  13. Glioblastoma mesenchymal subtype enhances antioxidant defence to reduce susceptibility to ferroptosis

    Article • Scientific Reports, September 2024, Springer Science + Business Media

    Professor Nunzio Vicario

  14. Sigma-1 receptor targeting inhibits connexin 43 based intercellular communication in chronic neuropathic pain

    Article • Inflammation Research, August 2024, Springer Science + Business Media

    Professor Nunzio Vicario

  15. Enhanced Antitumor Activity by the Combination of Dasatinib and Selinexor in Chronic Myeloid Leukemia

    Article • Pharmaceuticals, July 2024, MDPI AG

    Professor Nunzio Vicario

  16. Melatonin Enhances Neural Differentiation of Adipose-Derived Mesenchymal Stem Cells

    Article • International Journal of Molecular Sciences, April 2024, MDPI AG

    Professor Nunzio Vicario

  17. Skeletal muscle of young females under resistance exercise exhibits a unique innate immune cell infiltration profile compared to males and elderly individuals

    Article • Journal of Muscle Research and Cell Motility, April 2024, Springer Science + Business Media

    Professor Nunzio Vicario

  18. Microglia and glioblastoma heterocellular interplay sustains tumour growth and proliferation as an off‐target effect of radiotherapy

    Article • Cell Proliferation, March 2024, Wiley

    Professor Nunzio Vicario, Dr Ali S Abdelhameed

  19. Plectin plays a role in the migration and volume regulation of astrocytes: a potential biomarker of glioblastoma

    Article • Journal of Biomedical Science, January 2024, Springer Science + Business Media

    Professor Nunzio Vicario

  20. SIRT5 rs12216101 T>G variant is associated with liver damage and mitochondrial dysfunction in patients with non-alcoholic fatty liver disease

    Article • Journal of Hepatology, January 2024, Elsevier

    Professor Nunzio Vicario, Sami Qadri

  21. Anaplastic thyroid cancer cells reduce CD71 levels to increase iron overload tolerance

    Article • Journal of Translational Medicine, November 2023, Springer Science + Business Media

    Professor Nunzio Vicario

  22. Sigma-1 Receptor Inhibition Reduces Mechanical Allodynia and Modulate Neuroinflammation in Chronic Neuropathic Pain

    Article • Molecular Neurobiology, November 2023, Springer Science + Business Media

    Professor Nunzio Vicario

  23. The Pleiotropic Effects of Fumarate: From Mitochondrial Respiration to Epigenetic Rewiring and DNA Repair Mechanisms

    Article • Metabolites, July 2023, MDPI AG

    Professor Nunzio Vicario

  24. Adipose-Derived Mesenchymal Stromal Cells: A Tool for Bone and Cartilage Repair

    Article • Biomedicines, June 2023, MDPI AG

    Professor Nunzio Vicario

  25. Proton boron capture therapy (PBCT) induces cell death and mitophagy in a heterotopic glioblastoma model

    Article • Communications Biology, April 2023, Springer Science + Business Media

    Professor Nunzio Vicario

  26. Mesenchymal stromal cells in tumor microenvironment remodeling of BCR-ABL negative myeloproliferative diseases

    Article • Frontiers in Oncology, February 2023, Frontiers

    Professor Nunzio Vicario

  27. Epigenetics and Metabolism Reprogramming Interplay into Glioblastoma: Novel Insights on Immunosuppressive Mechanisms

    Article • Antioxidants, January 2023, MDPI AG

    Professor Nunzio Vicario

  28. Lactate Rewrites the Metabolic Reprogramming of Uveal Melanoma Cells and Induces Quiescence Phenotype

    Article • International Journal of Molecular Sciences, December 2022, MDPI AG

    Professor Nunzio Vicario

  29. Neurotrophic and immunomodulatory effects of olfactory ensheathing cells as a strategy for neuroprotection and regeneration

    Article • Frontiers in Immunology, December 2022, Frontiers

    Professor Nunzio Vicario

  30. The Role of Epigenetics in Neuroinflammatory-Driven Diseases

    Article • International Journal of Molecular Sciences, December 2022, MDPI AG

    Professor Nunzio Vicario

  31. Sex-dependent neuro-deconvolution analysis of Alzheimer's disease brain transcriptomes according to CHI3L1 expression levels

    Article • Journal of Neuroimmunology, December 2022, Elsevier

    Professor Nunzio Vicario

  32. GJA1/CX43 High Expression Levels in the Cervical Spinal Cord of ALS Patients Correlate to Microglia-Mediated Neuroinflammatory Profile

    Article • Biomedicines, September 2022, MDPI AG

    Professor Nunzio Vicario

  33. Connexins Signatures of the Neurovascular Unit and Their Physio-Pathological Functions

    Article • International Journal of Molecular Sciences, August 2022, MDPI AG

    Professor Nunzio Vicario

  34. Neuroprotective Role of α-Lipoic Acid in Iron-Overload-Mediated Toxicity and Inflammation in In Vitro and In Vivo Models

    Article • Antioxidants, August 2022, MDPI AG

    Professor Nunzio Vicario

  35. Lactate modulates microglia polarization via IGFBP6 expression and remodels tumor microenvironment in glioblastoma

    Article • Medical Oncology, June 2022, Springer Science + Business Media

    Professor Nunzio Vicario

  36. Mu and Delta Opioid Receptor Targeting Reduces Connexin 43-Based Heterocellular Coupling during Neuropathic Pain

    Article • International Journal of Molecular Sciences, May 2022, MDPI AG

    Professor Nunzio Vicario

  37. Hedgehog signaling pathways in multiple myeloma

    Article • Annals of Research in Oncology, May 2022, Edra SpA

    Professor Nunzio Vicario

  38. Lactate Induces the Expressions of MCT1 and HCAR1 to Promote Tumor Growth and Progression in Glioblastoma

    Article • Frontiers in Oncology, April 2022, Frontiers

    Professor Nunzio Vicario

  39. The Hallmarks of Glioblastoma: Heterogeneity, Intercellular Crosstalk and Molecular Signature of Invasiveness and Progression

    Article • Biomedicines, March 2022, MDPI AG

    Professor Nunzio Vicario

  40. The Crosstalk between GPR81/IGFBP6 Promotes Breast Cancer Progression by Modulating Lactate Metabolism and Oxidative Stress

    Article • Antioxidants, January 2022, MDPI AG

    Professor Nunzio Vicario

  41. CXCL12/CXCR4 axis supports mitochondrial trafficking in tumor myeloma microenvironment

    Article • Oncogenesis, January 2022, Springer Science + Business Media

    Professor Nunzio Vicario

  42. IGFBP-6/sonic hedgehog/TLR4 signalling axis drives bone marrow fibrotic transformation in primary myelofibrosis

    Article • Aging, December 2021, Impact Journals, LLC

    Professor Nunzio Vicario

  43. The Multimodal MOPr/DOPr Agonist LP2 Reduces Allodynia in Chronic Constriction Injured Rats by Rescue of TGF-β1 Signalling

    Article • Frontiers in Pharmacology, October 2021, Frontiers

    Professor Nunzio Vicario

  44. Adult stem cell niches for tissue homeostasis

    Article • Journal of Cellular Physiology, August 2021, Wiley

    Professor Nunzio Vicario

  45. Connexin 43 and Sonic Hedgehog Pathway Interplay in Glioblastoma Cell Proliferation and Migration

    Article • Biology, August 2021, MDPI AG

    Professor Nunzio Vicario

  46. Clobetasol promotes neuromuscular plasticity in mice after motoneuronal loss via sonic hedgehog signaling, immunomodulation and metabolic rebalancing

    Article • Cell Death and Disease, June 2021, Springer Science + Business Media

    Professor Nunzio Vicario

  47. Stem cells traffic functional mitochondria via EVs

    Article • PLoS Biology, April 2021, PLOS

    Stefano Pluchino, Professor Nunzio Vicario

  48. Focus on Osteosclerotic Progression in Primary Myelofibrosis

    Article • Biomolecules, January 2021, MDPI AG

    Professor Nunzio Vicario

  49. Connexin expression decreases during adipogenic differentiation of human adipose-derived mesenchymal stem cells

    Article • Molecular Biology Reports, November 2020, Springer Science + Business Media

    Professor Nunzio Vicario

  50. The Role of Hypoxia and SRC Tyrosine Kinase in Glioblastoma Invasiveness and Radioresistance

    Article • Cancers, October 2020, MDPI AG

    Professor Nunzio Vicario

  51. Iron regulates myeloma cell/macrophage interaction and drives resistance to bortezomib

    Article • Redox Biology, September 2020, Elsevier

    Professor Nunzio Vicario

  52. Inhibition of TLR4 Signaling Affects Mitochondrial Fitness and Overcomes Bortezomib Resistance in Myeloma Plasma Cells

    Article • Cancers, July 2020, MDPI AG

    Professor Nunzio Vicario

  53. Increased expression of connexin 43 in a mouse model of spinal motoneuronal loss

    Article • Aging, June 2020, Impact Journals, LLC

    Professor Nunzio Vicario

  54. Intercellular communication and ion channels in neuropathic pain chronicization

    Article • Inflammation Research, June 2020, Springer Science + Business Media

    Professor Nunzio Vicario

  55. SRC Tyrosine Kinase Inhibitor and X-rays Combined Effect on Glioblastoma Cell Lines

    Article • International Journal of Molecular Sciences, May 2020, MDPI AG

    Professor Nunzio Vicario

  56. Chronic α-Synuclein Accumulation in Rat Hippocampus Induces Lewy Bodies Formation and Specific Cognitive Impairments

    Article • eNeuro, May 2020, Society for Neuroscience

    Professor Nunzio Vicario

  57. Mitochondrial Functions, Energy Metabolism and Protein Glycosylation are Interconnected Processes Mediating Resistance to Bortezomib in Multiple Myeloma Cells

    Article • Biomolecules, April 2020, MDPI AG

    Professor Nunzio Vicario

  58. Olfactory Ensheathing Cells express both Ghrelin and Ghrelin Receptor in vitro: a new hypothesis in favor of a neurotrophic effect

    Article • Neuropeptides, February 2020, Elsevier

    Professor Nunzio Vicario

  59. Ixazomib Improves Bone Remodeling and Counteracts Sonic Hedgehog Signaling Inhibition Mediated by Myeloma Cells

    Article • Cancers, January 2020, MDPI AG

    Professor Nunzio Vicario

  60. A novel in situ multiplex immunofluorescence panel for the assessment of tumor immunopathology and response to virotherapy in pediatric glioblastoma reveals a role for checkpoint protein inhibition

    Article • OncoImmunology, October 2019, Taylor & Francis

    Dr. Joshua D Bernstock, Professor Nunzio Vicario

  61. Compensatory changes in degenerating spinal motoneurons sustain functional sparing in the SOD1‐G93A mouse model of amyotrophic lateral sclerosis

    Article • The Journal of Comparative Neurology, August 2019, Wiley

    Professor Nunzio Vicario

  62. Middle-aged healthy women and Alzheimer's disease patients present an overlapping of brain cell transcriptional profile

    Article • Neuroscience, May 2019, Elsevier

    Professor Nunzio Vicario

  63. Simultaneous Activation of Mu and Delta Opioid Receptors Reduces Allodynia and Astrocytic Connexin 43 in an Animal Model of Neuropathic Pain

    Article • Molecular Neurobiology, April 2019, Springer Science + Business Media

    Professor Nunzio Vicario

  64. Clobetasol Modulates Adult Neural Stem Cell Growth via Canonical Hedgehog Pathway Activation

    Article • International Journal of Molecular Sciences, April 2019, MDPI AG

    Professor Nunzio Vicario

  65. SUMOylation in Glioblastoma: A Novel Therapeutic Target

    Article • International Journal of Molecular Sciences, April 2019, MDPI AG

    Professor Nunzio Vicario

  66. Neuroprotective effects of Rosmarinus officinalis L. extract in oxygen glucose deprivation (OGD)-injured human neural-like cells

    Article • Natural Product Research, April 2019, Taylor & Francis

    Professor Nunzio Vicario, Rosalba Parenti, Carmela Parenti

  67. SUMOylation promotes survival and integration of neural stem cell grafts in ischemic stroke

    Article • EBioMedicine, April 2019, Elsevier

    Professor Nunzio Vicario

  68. Safety and efficacy of oncolytic HSV-1 G207 inoculated into the cerebellum of mice

    Article • Cancer Gene Therapy, March 2019, Springer Science + Business Media

    Professor Nunzio Vicario

  69. Neuromuscular Plasticity in a Mouse Neurotoxic Model of Spinal Motoneuronal Loss

    Article • International Journal of Molecular Sciences, March 2019, MDPI AG

    Professor Nunzio Vicario

  70. The Biochemical and Pharmacological Properties of Ozone: The Smell of Protection in Acute and Chronic Diseases

    Article • International Journal of Molecular Sciences, February 2019, MDPI AG

    Professor Nunzio Vicario

  71. α-Lipoic Acid Reduces Iron-induced Toxicity and Oxidative Stress in a Model of Iron Overload

    Article • International Journal of Molecular Sciences, January 2019, MDPI AG

    Professor Nunzio Vicario

  72. An innovative silicon-chip for sensitive real time PCR improvement in pathogen detection

    Article • The Analyst, January 2019, Royal Society of Chemistry

    Professor Nunzio Vicario

  73. An Advanced, Silicon-Based Substrate for Sensitive Nucleic Acids Detection

    Article • Sensors, September 2018, MDPI AG

    Professor Nunzio Vicario

  74. Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation

    Article • Cell Stem Cell, March 2018, Elsevier

    Dr. Joshua D Bernstock, Professor Nunzio Vicario

  75. Evaluation of RGD functionalization in hybrid hydrogels as 3D neural stem cell culture systems

    Article • Biomaterials Science, January 2018, Royal Society of Chemistry

    Professor Nunzio Vicario

  76. Connexins in the Central Nervous System: Physiological Traits and Neuroprotective Targets

    Article • Frontiers in Physiology, December 2017, Frontiers

    Professor Nunzio Vicario

  77. OECs and Cx43 role in neuroprotection

    Article • Journal of Cellular and Molecular Medicine, May 2017, Wiley

    Professor Nunzio Vicario, Rosalba Parenti

  78. Neural stem cell transplantation in ischemic stroke: A role for preconditioning and cellular engineering

    Article • Journal of Cerebral Blood Flow & Metabolism, March 2017, SAGE Publications

    Dr. Joshua D Bernstock, Stefano Pluchino, Professor Nunzio Vicario

  79. Wilms’ tumor gene 1 silencing inhibits proliferation of human osteosarcoma MG-63 cell line by cell cycle arrest and apoptosis activation

    Article • Oncotarget, February 2017, Impact Journals, LLC

    Rosalba Parenti, Professor Nunzio Vicario

  80. Repeated activation of delta opioid receptors counteracts nerve injury-induced TNF-α up-regulation in the sciatic nerve of rats with neuropathic pain

    Article • Molecular Pain, January 2016, SAGE Publications

    Carmela Parenti, Professor Nunzio Vicario