Mohamed Attwa

All Stories

1. 
   An ultra-fast validated green UPLC-MS/MS approach for the evaluation of zanubrutinib in vitro metabolic stability in human liver microsomes: Screening for in silico metabolic lability, ADME parameters, and DEREK toxic alerts

   Article • Acta Chromatographica, August 2025, Akademiai Kiado

   Mohamed Attwa

2. 
   Validated and green UPLC-MS/MS method for belumosudil quantification in human liver microsomes: Application to in vitro metabolic stability assessment

   Article • Acta Chromatographica, March 2025, Akademiai Kiado

   Mohamed Attwa

3. 
   Development and validation of a sensitive and fast bioanalytical LC-MS/MS assay for the quantitation of venetoclax and azacitidine in Rat Plasma: Application to pharmacokinetic study

   Article • Analytical Biochemistry, March 2025, Elsevier

   Mohamed Attwa

4. 
   An ultra-fast validated green UPLC-MS/MS method for the quantification of osimertinib in human liver microsomes: Screening for ADME parameters and in vitro metabolic stability

   Article • Acta Chromatographica, January 2025, Akademiai Kiado

   Mohamed Attwa

5. 
   An ultra-fast UPLC-MS/MS approach for the quantification of baricitinib in the HLM matrix: greenness assessment with application to in vitro and in silico metabolic stability studies

   Article • Analytical Methods, January 2025, Royal Society of Chemistry

   Mohamed Attwa

6. 
   An Ultra-Fast Validated Green UPLC-MS/MS Approach for Assessing Revumenib in Human Liver Microsomes: In Vitro Absorption, Distribution, Metabolism, and Excretion and Metabolic Stability Evaluation

   Article • Medicina, November 2024, MDPI AG

   Mohamed Attwa

7. 
   A Green Approach: Optimization of the UPLC Method Using DoE Software for Concurrent Quantification of Pioglitazone and Dapagliflozin in a SNEDDS Formulation for the Treatment of Diabetes

   Article • ACS Omega, November 2024, American Chemical Society (ACS)

   Mohamed Attwa

8. 
   An Ultra-Fast Green UHPLC-MS/MS Method for Assessing the In Vitro Metabolic Stability of Dovitinib: In Silico Study for Absorption, Distribution, Metabolism, Excretion, Metabolic Lability, and DEREK Alerts

   Article • Medicina, October 2024, MDPI AG

   Mohamed Attwa

9. 
   Assessment of the in vitro metabolic stability of CEP-37440, a selective FAK/ALK inhibitor, in HLMs using fast UPLC–MS/MS method: in silico metabolic lability and DEREK alerts screening

   Article • Frontiers in Chemistry, September 2024, Frontiers

   Mohamed Attwa

10. 
    Polycaprolactone—Vitamin E TPGS Micellar Formulation for Oral Delivery of Paclitaxel

    Article • Polymers, August 2024, MDPI AG

    Mohamed Attwa

11. 
    An ultra‐fast green ultra‐high‐performance liquid chromatography‐tandem mass spectrometry method for estimating the in vitro metabolic stability of zotizalkib in human liver microsomes

    Article • Journal of Separation Science, August 2024, Wiley

    Mohamed Attwa

12. 
    An ultra‐fast ultra‐high‐performance liquid chromatography‐tandem mass spectrometry method for estimating the in vitro metabolic stability of palbociclib in human liver microsomes: In silico study for metabolic lability, absorption, distribution, metab...

    Article • Journal of Separation Science, August 2024, Wiley

    Mohamed Attwa

13. 
    Characterization of the in vitro metabolic profile of nazartinib in HLMs using UPLC-MS/MS method: In silico metabolic lability and DEREK structural alerts screening using StarDrop software

    Article • Heliyon, July 2024, Elsevier

    Mohamed Attwa

14. 
    Ultra-fast UPLC–MS/MS approach for estimating X-376 in human liver microsomes: Evaluation of metabolic stability via in silico software and in vitro analysis

    Article • Journal of Pharmacological and Toxicological Methods, July 2024, Elsevier

    Mohamed Attwa

15. 
    Editorial: Drug metabolism-induced organ toxicity

    Article • Frontiers in Pharmacology, January 2024, Frontiers

    Mohamed Attwa

16. 
    Ion Trap LC/MS reveals the generation of reactive intermediates in acalabrutinib metabolism: phase I metabolic profiling and bioactivation pathways elucidation

    Article • RSC Advances, January 2024, Royal Society of Chemistry

    Mohamed Attwa

17. 
    Phospholipid-based nano drug delivery system of curcumin using MSP1D1 protein and poloxamer 407: a comparative study for targeted drug delivery to the brain

    Article • Journal of Nanoparticle Research, January 2024, Springer Science + Business Media

    Mohamed Attwa

18. 
    Identification of Indazole-Based Thiadiazole-Bearing Thiazolidinone Hybrid Derivatives: Theoretical and Computational Approaches to Develop Promising Anti-Alzheimer’s Candidates

    Article • Pharmaceuticals, November 2023, MDPI AG

    Mohamed Attwa

19. 
    The Synthesis, In Vitro Bio-Evaluation, and In Silico Molecular Docking Studies of Pyrazoline–Thiazole Hybrid Analogues as Promising Anti-α-Glucosidase and Anti-Urease Agents

    Article • Pharmaceuticals, November 2023, MDPI AG

    Mohamed Attwa

20. 
    Supramolecular Structure, Hirshfeld Surface Analysis, Morphological Study and DFT Calculations of the Triphenyltetrazolium Cobalt Thiocyanate Complex

    Article • Crystals, November 2023, MDPI AG

    Mohamed Attwa

21. 
    Ionophore-Based Polymeric Sensors for Potentiometric Assay of the Anticancer Drug Gemcitabine in Pharmaceutical Formulation: A Comparative Study

    Article • Molecules, November 2023, MDPI AG

    Mohamed Attwa

22. 
    Selective Stability Indicating Liquid Chromatographic Method Based on Quality by Design Framework and In Silico Toxicity Assessment for Infigratinib and Its Degradation Products

    Article • Molecules, November 2023, MDPI AG

    Mohamed Attwa

23. 
    An Ultrafast UPLC–MS/MS Method for Characterizing the In Vitro Metabolic Stability of Acalabrutinib

    Article • Molecules, October 2023, MDPI AG

    Mohamed Attwa

24. 
    Evaluation of Alectinib Metabolic Stability in HLMs Using Fast LC-MS/MS Method: In Silico ADME Profile, P450 Metabolic Lability, and Toxic Alerts Screening

    Article • Pharmaceutics, October 2023, MDPI AG

    Mohamed Attwa

25. 
    Applicable pharmacokinetic study: Development and validation of bioanalytical LC-MS/MS method for the simultaneous quantification of cytarabine and glasdegib used for the treatment of acute myeloid leukemia

    Article • Arabian Journal of Chemistry, October 2023, Scientific Scholar

    Mohamed Attwa

26. 
    LC–MS/MS method for the quantitation of decitabine and venetoclax in rat plasma after SPE: Application to pharmacokinetic study

    Article • Saudi Pharmaceutical Journal, September 2023, Springer Science + Business Media

    Mohamed Attwa

27. 
    A Sensitive, Green, and Fast LC–MS/MS Analytical Method for the Quantification of Ribociclib: Evaluation of the Metabolic Stability in HLMs

    Article • Separations, August 2023, MDPI AG

    Mohamed Attwa

28. 
    Structural Analysis and Reactivity Insights of (E)-Bromo-4-((4-((1-(4-chlorophenyl)ethylidene)amino)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)-5-((2-isopropylcyclohexyl)oxy) Furan-2(5H)-one: A Combined Approach Using Single-Crystal X-ray Diffraction, Hirshf...

    Article • Crystals, August 2023, MDPI AG

    Mohamed Attwa

29. 
    A Fast LC-MS/MS Methodology for Estimating Savolitinib in Human Liver Microsomes: Assessment of Metabolic Stability Using In Vitro Metabolic Incubation and In Silico Software Analysis

    Article • Separations, August 2023, MDPI AG

    Mohamed Attwa

30. 
    Crosstalk between aryl hydrocarbon receptor (AhR) and BCL-2 pathways suggests the use of AhR antagonist to maintain normal differentiation state of mammary epithelial cells during BCL-2 inhibition therapy

    Article • Journal of Advanced Research, August 2023, Elsevier

    Mohamed Attwa

31. 
    Enhanced Codelivery of Gefitinib and Azacitidine for Treatment of Metastatic-Resistant Lung Cancer Using Biodegradable Lipid Nanoparticles

    Article • Materials, July 2023, MDPI AG

    Mohamed Attwa

32. 
    Exploring the Chemical Reactivity, Molecular Docking, Molecular Dynamic Simulation and ADMET Properties of a Tetrahydrothienopyridine Derivative Using Computational Methods

    Article • Crystals, June 2023, MDPI AG

    Mohamed Attwa

33. 
    Fabrication and Applications of Potentiometric Membrane Sensors Based on γ-Cyclodextrin and Calixarene as Ionophores for the Determination of a Histamine H1-Receptor Antagonist: Fexofenadine

    Article • Polymers, June 2023, MDPI AG

    Mohamed Attwa

34. 
    Reactive intermediates formation and bioactivation pathways of spebrutinib revealed by LC-MS/MS: In vitro and in silico metabolic study

    Article • Heliyon, June 2023, Elsevier

    Mohamed Attwa

35. 
    An LC–MS/MS Analytical Method for Quantifying Tepotinib in Human Liver Microsomes: Application to In Vitro and In Silico Metabolic Stability Estimation

    Article • Separations, May 2023, MDPI AG

    Mohamed Attwa

36. 
    Investigation of Fenebrutinib Metabolism and Bioactivation Using MS3 Methodology in Ion Trap LC/MS

    Article • Molecules, May 2023, MDPI AG

    Mohamed Attwa

37. 
    Development of a Fast and Sensitive UPLC–MS/MS Analytical Methodology for Fenebrutinib Estimation in Human Liver Microsomes: In Vitro and In Silico Metabolic Stability Evaluation

    Article • Separations, May 2023, MDPI AG

    Mohamed Attwa

38. 
    An UPLC–ESI–MS/MS Bioanalytical Methodology for the Quantification of Gilteritinib in Human Liver Microsomes: Application to In Vitro and In Silico Metabolic Stability Estimation

    Article • Separations, April 2023, MDPI AG

    Mohamed Attwa

39. 
    A Rapid and Sensitive UPLC-MS/MS Method for Quantifying Capmatinib in Human Liver Microsomes: Evaluation of Metabolic Stability by In Silico and In Vitro Analysis

    Article • Separations, April 2023, MDPI AG

    Mohamed Attwa

40. 
    Assessment of In Silico and In Vitro Selpercatinib Metabolic Stability in Human Liver Microsomes Using a Validated LC-MS/MS Method

    Article • Molecules, March 2023, MDPI AG

    Mohamed Attwa

41. 
    Development and Validation of a Rapid LC-MS/MS Method for Quantifying Alvocidib: In Silico and In Vitro Metabolic Stability Estimation in Human Liver Microsomes

    Article • Molecules, March 2023, MDPI AG

    Mohamed Attwa

42. 
    Development of an LC-MS/MS Method for Quantification of Sapitinib in Human Liver Microsomes: In Silico and In Vitro Metabolic Stability Evaluation

    Article • Molecules, March 2023, MDPI AG

    Mohamed Attwa

43. 
    Rapid LC-MS/MS Bosutinib Quantification with Applications in Metabolic Stability Estimation

    Article • Molecules, February 2023, MDPI AG

    Mohamed Attwa

44. 
    A Liquid Chromatography Tandem Mass Spectrometry Method for the Simultaneous Estimation of the Dopamine Receptor Antagonist LE300 and Its N-methyl Metabolite in Plasma: Application to a Pharmacokinetic Study

    Article • Molecules, February 2023, MDPI AG

    Mohamed Attwa

45. 
    Piperazine ring toxicity in three novel anti-breast cancer drugs: an in silico and in vitro metabolic bioactivation approach using olaparib as a case study

    Article • Naunyn-Schmiedeberg s Archives of Pharmacology, February 2023, Springer Science + Business Media

    Mohamed Attwa

46. 
    Development and validation of an UPLC-ESI-MS/MS method for quantification of duvelisib in plasma: application to pharmacokinetic study in rats

    Article • RSC Advances, January 2023, Royal Society of Chemistry

    Mohamed Attwa

47. 
    Vandetanib

    Article • January 2023, Elsevier

    Mohamed Attwa

48. 
    A Rapid and Sensitive Liquid Chromatography-Tandem Mass Spectrometry Bioanalytical Method for the Quantification of Encorafenib and Binimetinib as a First-Line Treatment for Advanced (Unresectable or Metastatic) Melanoma—Application to a Pharmacokineti...

    Article • Molecules, December 2022, MDPI AG

    Mohamed Attwa

49. 
    A Novel Green Micellar HPLC-UV Method for the Estimation of Vandetanib in Pure Form, Human Urine, Human Plasma and Human Liver Microsomes Matrices with Application to Metabolic Stability Evaluation

    Article • Molecules, December 2022, MDPI AG

    Mohamed Attwa

50. 
    Simvastatin: In Vitro Metabolic Profiling of a Potent Competitive HMG-CoA Reductase Inhibitor

    Article • Separations, November 2022, MDPI AG

    Mohamed Attwa

51. 
    Nicotine and cotinine quantification after a 4-week inhalation of electronic cigarette vapors in male and female mice using UPLC-MS/MS

    Article • Saudi Medical Journal, July 2022, Saudi Medical Journal

    Mohamed Attwa

52. 
    Detection and characterization of simvastatin and its metabolites in rat tissues and biological fluids using MALDI high resolution mass spectrometry approach

    Article • Scientific Reports, March 2022, Springer Science + Business Media

    Mohamed Attwa

53. 
    Estimation of zorifertinib metabolic stability in human liver microsomes using LC–MS/MS

    Article • Journal of Pharmaceutical and Biomedical Analysis, March 2022, Elsevier

    Mohamed Attwa

54. 
    A validated LC-MS/MS analytical method for the quantification of pemigatinib: metabolic stability evaluation in human liver microsomes

    Article • RSC Advances, January 2022, Royal Society of Chemistry

    Mohamed Attwa

55. 
    Development of novel univariate and multivariate validated chemometric methods for the analysis of dasatinib, sorafenib, and vandetanib in pure form, dosage forms and biological fluids

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, January 2022, Elsevier

    Mohamed Attwa

56. 
    Lodenafil

    Article • January 2022, Elsevier

    Mohamed Attwa

57. 
    Profiling of in vivo, in vitro and reactive zorifertinib metabolites using liquid chromatography ion trap mass spectrometry

    Article • RSC Advances, January 2022, Royal Society of Chemistry

    Mohamed Attwa

58. 
    Spectroscopic, molecular docking and dynamic simulation studies of binding between the new anticancer agent olmutinib and human serum albumin

    Article • Journal of Biomolecular Structure and Dynamics, November 2021, Taylor & Francis

    Mohamed Attwa

59. 
    Simple and efficient spectroscopic-based univariate sequential methods for simultaneous quantitative analysis of vandetanib, dasatinib, and sorafenib in pharmaceutical preparations and biological fluids

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, November 2021, Elsevier

    Mohamed Attwa

60. 
    LC-MS/MS method for the quantification of the anti-cancer agent infigratinib: Application for estimation of metabolic stability in human liver microsomes

    Article • Journal of Chromatography B, August 2021, Elsevier

    Mohamed Attwa

61. 
    A Validated LC–MS/MS Assay for the Simultaneous Quantification of the FDA-Approved Anticancer Mixture (Encorafenib and Binimetinib): Metabolic Stability Estimation

    Article • Molecules, May 2021, MDPI AG

    Mohamed Attwa

62. 
    Identification and characterization of in vitro, in vivo, and reactive metabolites of tandutinib using liquid chromatography ion trap mass spectrometry

    Article • Analytical Methods, January 2021, Royal Society of Chemistry

    Mohamed Attwa

63. 
    <p>Characterization of Stable and Reactive Metabolites of the Anticancer Drug, Ensartinib, in Human Liver Microsomes Using LC-MS/MS: An in silico and Practical Bioactivation Approach</p>

    Article • Drug Design Development and Therapy, November 2020, Taylor & Francis

    Mohamed Attwa

64. 
    Effective quantification of ravidasvir (an NS5A inhibitor) and sofosbuvir in rat plasma by validated LC-MS/MS method and its application to pharmacokinetic study

    Article • Arabian Journal of Chemistry, November 2020, Scientific Scholar

    Mohamed Attwa

65. 
    Identification of Iminium Intermediates Generation in the Metabolism of Tepotinib Using LC-MS/MS: In Silico and Practical Approaches to Bioactivation Pathway Elucidation

    Article • Molecules, October 2020, MDPI AG

    Mohamed Attwa

66. 
    Development and validation of an HPLC-MS/MS method for the determination of filgotinib, a selective Janus kinase 1 inhibitor: Application to a metabolic stability study

    Article • Journal of Chromatography B, October 2020, Elsevier

    Mohamed Attwa

67. 
    <p>LC-MS/MS Estimation of the Anti-Cancer Agent Tandutinib Levels in Human Liver Microsomes: Metabolic Stability Evaluation Assay</p>

    Article • Drug Design Development and Therapy, October 2020, Taylor & Francis

    Mohamed Attwa

68. 
    Exploring the effect of khat (Catha edulis) chewing on the pharmacokinetics of the antiplatelet drug clopidogrel in rats using the newly developed LC-MS/MS technique

    Article • Open Chemistry, June 2020, De Gruyter

    Mohamed Attwa

69. 
    Fragmentation pattern of certain isatin–indole antiproliferative conjugates with application to identify their in vitro metabolic profiles in rat liver microsomes by liquid chromatography tandem mass spectrometry

    Article • Open Chemistry, June 2020, De Gruyter

    Mohamed Attwa

70. 
    EGFR Inhibitor Gefitinib Induces Cardiotoxicity through the Modulation of Cardiac PTEN/Akt/FoxO3a Pathway and Reactive Metabolites Formation: In Vivo and in Vitro Rat Studies

    Article • Chemical Research in Toxicology, May 2020, American Chemical Society (ACS)

    Mohamed Attwa

71. 
    <p>Metabolic Stability Assessment of New PARP Inhibitor Talazoparib Using Validated LC–MS/MS Methodology: In silico Metabolic Vulnerability and Toxicity Studies</p>

    Article • Drug Design Development and Therapy, February 2020, Taylor & Francis

    Mohamed Attwa

72. 
    Correction: In silico and in vitro metabolism of ribociclib: a mass spectrometric approach to bioactivation pathway elucidation and metabolite profiling

    Article • RSC Advances, January 2020, Royal Society of Chemistry

    Mohamed Attwa

73. 
    In silico and in vitro metabolism of ribociclib: a mass spectrometric approach to bioactivation pathway elucidation and metabolite profiling

    Article • RSC Advances, January 2020, Royal Society of Chemistry

    Mohamed Attwa

74. 
    <p>A New Validated HPLC-MS/MS Method for Quantification and Pharmacokinetic Evaluation of Dovitinib, a Multi-Kinase Inhibitor, in Mouse Plasma</p>

    Article • Drug Design Development and Therapy, January 2020, Taylor & Francis

    Mohamed Attwa

75. 
    Identification and characterization of in silico, in vivo, in vitro, and reactive metabolites of infigratinib using LC-ITMS: bioactivation pathway elucidation and in silico toxicity studies of its metabolites

    Article • RSC Advances, January 2020, Royal Society of Chemistry

    Mohamed Attwa

76. 
    <p>Metabolic Stability Assessment of Larotrectinib Using Liquid Chromatography Tandem Mass Spectrometry</p>

    Article • Drug Design Development and Therapy, January 2020, Taylor & Francis

    Mohamed Attwa

77. 
    Phase I metabolic profiling and unexpected reactive metabolites in human liver microsome incubations of X-376 using LC-MS/MS: bioactivation pathway elucidation andin silicotoxicity studies of its metabolites

    Article • RSC Advances, January 2020, Royal Society of Chemistry

    Mohamed Attwa

78. 
    Detection and characterization of olmutinib reactive metabolites by LC–MS/MS: Elucidation of bioactivation pathways

    Article • Journal of Separation Science, December 2019, Wiley

    Mohamed Attwa

79. 
    Liquid chromatography–tandem mass spectrometry metabolic profiling of nazartinib reveals the formation of unexpected reactive metabolites

    Article • Royal Society Open Science, August 2019, Royal Society Publishing

    Mohamed Attwa

80. 
    Belizatinib: Novel reactive intermediates and bioactivation pathways characterized by LC–MS/MS

    Article • Journal of Pharmaceutical and Biomedical Analysis, July 2019, Elsevier

    Mohamed Attwa

81. 
    A highly sensitive LC-MS/MS method to determine novel Bruton's tyrosine kinase inhibitor spebrutinib: application to metabolic stability evaluation

    Article • Royal Society Open Science, June 2019, Royal Society Publishing

    Mohamed Attwa

82. 
    Validated LC-MS/MS assay for quantification of the newly approved tyrosine kinase inhibitor, dacomitinib, and application to investigating its metabolic stability

    Article • PLOS One, April 2019, PLOS

    Dr Ali S Abdelhameed, Mohamed Attwa

83. 
    Reactive intermediates and bioactivation pathways characterization of avitinib by LC–MS/MS: In vitro metabolic investigation

    Article • Journal of Pharmaceutical and Biomedical Analysis, February 2019, Elsevier

    Mohamed Attwa

84. 
    A simple liquid chromatography-tandem mass spectrometry method to accurately determine the novel third-generation EGFR-TKI naquotinib with its applicability to metabolic stability assessment

    Article • RSC Advances, January 2019, Royal Society of Chemistry

    Mohamed Attwa

85. 
    Identification of reactive intermediate formation and bioactivation pathways in Abemaciclib metabolism by LC–MS/MS: in vitro metabolic investigation

    Article • Royal Society Open Science, January 2019, Royal Society Publishing

    Mohamed Attwa

86. 
    Reactive intermediates in copanlisib metabolism identified by LC-MS/MS: phase I metabolic profiling

    Article • RSC Advances, January 2019, Royal Society of Chemistry

    Mohamed Attwa

87. 
    Reactive intermediates in naquotinib metabolism identified by liquid chromatography-tandem mass spectrometry: phase I metabolic profiling

    Article • RSC Advances, January 2019, Royal Society of Chemistry

    Mohamed Attwa

88. 
    Sapitinib: reactive intermediates and bioactivation pathways characterized by LC-MS/MS

    Article • RSC Advances, January 2019, Royal Society of Chemistry

    Mohamed Attwa

89. 
    Validated liquid chromatography tandem mass spectrometry for simultaneous quantification of foretinib and lapatinib, and application to metabolic stability investigation

    Article • RSC Advances, January 2019, Royal Society of Chemistry

    Mohamed Attwa

90. 
    LC-ESI-MS/MS identification and characterization of ponatinib in vivo phase I and phase II metabolites

    Article • Clinica Chimica Acta, October 2018, Elsevier

    Mohamed Attwa

91. 
    Investigation of metabolic degradation of new ALK inhibitor: Entrectinib by LC-MS/MS

    Article • Clinica Chimica Acta, October 2018, Elsevier

    Mohamed Attwa

92. 
    LC–MS/MS reveals the formation of iminium and quinone methide reactive intermediates in entrectinib metabolism: In vivo and in vitro metabolic investigation

    Article • Journal of Pharmaceutical and Biomedical Analysis, October 2018, Elsevier

    Mohamed Attwa

93. 
    Identification and characterization of in vivo, in vitro and reactive metabolites of vandetanib using LC–ESI–MS/MS

    Article • Chemistry Central Journal, September 2018, Springer Science + Business Media

    Mohamed Attwa

94. 
    LC-MS/MS reveals the formation of reactive ortho -quinone and iminium intermediates in saracatinib metabolism: Phase I metabolic profiling

    Article • Clinica Chimica Acta, July 2018, Elsevier

    Mohamed Attwa

95. 
    Characterization of in vivo metabolites in rat urine following an oral dose of masitinib by liquid chromatography tandem mass spectrometry

    Article • Chemistry Central Journal, May 2018, Springer Science + Business Media

    Mohamed Attwa

96. 
    Development and validation of an HPLC–MS/MS method for the determination of arginine-vasopressin receptor blocker conivaptan in human plasma and rat liver microsomes: application to a metabolic stability study

    Article • Chemistry Central Journal, May 2018, Springer Science + Business Media

    Mohamed Attwa

97. 
    Investigation of metabolic stability of the novel ALK inhibitor brigatinib by liquid chromatography tandem mass spectrometry

    Article • Clinica Chimica Acta, May 2018, Elsevier

    Mohamed Attwa

98. 
    A reliable and stable method for the determination of foretinib in human plasma by LC-MS/MS: Application to metabolic stability investigation and excretion rate

    Article • European Journal of Mass Spectrometry, April 2018, SAGE Publications

    Mohamed Attwa

99. 
    Characterization of reactive intermediates formation in dacomitinib metabolism and bioactivation pathways elucidation by LC-MS/MS: in vitro phase I metabolic investigation

    Article • RSC Advances, January 2018, Royal Society of Chemistry

    Mohamed Attwa

100. 
     LC-ESI-MS/MS reveals the formation of reactive intermediates in brigatinib metabolism: elucidation of bioactivation pathways

     Article • RSC Advances, January 2018, Royal Society of Chemistry

     Mohamed Attwa

101. 
     Investigation of the metabolic stability of olmutinib by validated LC-MS/MS: quantification in human plasma

     Article • RSC Advances, January 2018, Royal Society of Chemistry

     Mohamed Attwa

102. 
     LC–MS/MS method for the quantification of masitinib in RLMs matrix and rat urine: application to metabolic stability and excretion rate

     Article • Chemistry Central Journal, December 2017, Springer Science + Business Media

     Mohamed Attwa

103. 
     Isatin-benzoazine molecular hybrids as potential antiproliferative agents: synthesis and in vitro pharmacological profiling

     Article • Drug Design Development and Therapy, August 2017, Dove Medical Press

     Dr Ali S Abdelhameed, Mohamed Attwa, Wagdy Eldehna

104. 
     Development and validation of HPLC-MS/MS method for the determination of lixivaptan in mouse plasma and its application in a pharmacokinetic study

     Article • Biomedical Chromatography, June 2017, Wiley

     Mohamed Attwa

105. 
     Liquid chromatography tandem mass spectrometry method for the quantification of vandetanib in human plasma and rat liver microsomes matrices: metabolic stability investigation

     Article • Chemistry Central Journal, May 2017, Springer Science + Business Media

     Mohamed Attwa

106. 
     Liquid chromatographic-tandem mass spectrometric assay for simultaneous quantitation of tofacitinib, cabozantinib and afatinib in human plasma and urine

     Article • Tropical Journal of Pharmaceutical Research, January 2017, African Journals Online (AJOL)

     Dr Ali S Abdelhameed, Mohamed Attwa

107. 
     Identification and characterization of in vitro phase I and reactive metabolites of masitinib using a LC-MS/MS method: bioactivation pathway elucidation

     Article • RSC Advances, January 2017, Royal Society of Chemistry

     Mohamed Attwa

108. 
     LC-MS/MS reveals the formation of aldehydes and iminium reactive intermediates in foretinib metabolism: phase I metabolic profiling

     Article • RSC Advances, January 2017, Royal Society of Chemistry

     Mohamed Attwa

109. 
     Correction: Detection and characterization of ponatinib reactive metabolites by liquid chromatography tandem mass spectrometry and elucidation of bioactivation pathways

     Article • RSC Advances, January 2017, Royal Society of Chemistry

     Mohamed Attwa

110. 
     Rapid validated liquid chromatographic method coupled with Tandem mass spectrometry for quantification of nintedanib in human plasma

     Article • Tropical Journal of Pharmaceutical Research, December 2016, African Journals Online (AJOL)

     Mohamed Attwa

111. 
     Validated LC-MS/MS Method for the Quantification of Ponatinib in Plasma: Application to Metabolic Stability

     Article • PLOS One, October 2016, PLOS

     Mohamed Attwa

112. 
     An LC-MS/MS method for rapid and sensitive high-throughput simultaneous determination of various protein kinase inhibitors in human plasma

     Article • Biomedical Chromatography, August 2016, Wiley

     Dr Ali S Abdelhameed, Mohamed Attwa

113. 
     Liquid chromatographic-mass spectrometric method for determination of drug content uniformity of two commonly used dermatology medications in a split-tablet dosage form

     Article • Tropical Journal of Pharmaceutical Research, July 2016, African Journals Online (AJOL)

     Dr Ali S Abdelhameed, Mohamed Attwa

114. 
     A highly efficient and sensitive LC-MS/MS method for the determination of afatinib in human plasma: application to a metabolic stability study

     Article • Biomedical Chromatography, January 2016, Wiley

     Dr Ali S Abdelhameed, Mohamed Attwa

115. 
     Detection and characterization of ponatinib reactive metabolites by liquid chromatography tandem mass spectrometry and elucidation of bioactivation pathways

     Article • RSC Advances, January 2016, Royal Society of Chemistry

     Mohamed Attwa

116. 
     Drug content and uniformity in commonly split tablets in dermatology

     Article • Journal of the American Academy of Dermatology, May 2014, Elsevier

     Mohamed Attwa

117. 
     Pseudo-MS3Approach Using Electrospray Mass Spectrometry (ESI-MS/MS) to Characterize Certain (2E)-2-[3-(1H-Imidazol-1-yl)-1-phenylpropylidene]hydrazinecarboxamide Derivatives

     Article • Journal of Chemistry, January 2014, Hindawi Publishing Corporation

     Dr Ali S Abdelhameed, Mohamed Attwa

118. 
     Multistage Fragmentation of Ion Trap Mass Spectrometry System and Pseudo-MS3of Triple Quadrupole Mass Spectrometry Characterize Certain (E)-3-(Dimethylamino)-1-arylprop-2-en-1-ones: A Comparative Study

     Article • The Scientific World JOURNAL, January 2014, Hindawi Publishing Corporation

     Dr Ali S Abdelhameed, Mohamed Attwa

119. 
     A Preliminary Study of Arecoline and Guvacoline Presence in the Saliva of a “Betel-Quid” Chewer Using Liquid-Chromatography Ion Trap Mass Spectrometry

     Article • European Journal of Mass Spectrometry, October 2013, SAGE Publications

     Mohamed Attwa

120. 
     Fragmentation Behavior Studies of Chalcones Employing Direct Analysis in Real Time (DART)

     Article • Mass Spectrometry Letters, June 2013, Korean Society for Mass Spectrometry

     Mohamed Attwa

121. 
     Induced in-source fragmentation pattern of certain novel (1Z,2E)-N-(aryl)propanehydrazonoyl chlorides by electrospray mass spectrometry (ESI-MS/MS)

     Article • Chemistry Central Journal, January 2013, Springer Science + Business Media

     Dr Ali S Abdelhameed, Mohamed Attwa

122. 
     High Throughput Quantitative Bioanalytical LC/MS/MS Determination of Gemifloxacin in Human Urine

     Article • Journal of Chemistry, January 2013, Hindawi Publishing Corporation

     Dr Ali S Abdelhameed, Mohamed Attwa

123. 
     Microwave-Assisted Solution-Phase Synthesis and DART-Mass Spectrometric Monitoring of a Combinatorial Library of Indolin-2,3-dione Schiff Bases with Potential Antimycobacterial Activity

     Article • Molecules, June 2011, MDPI AG

     Mohamed Attwa