All Stories

  1. Beyond the Score: Fixed-Budget Benchmarking of Virtual Screening Integration Strategies for Decision-Centric Drug Discovery
  2. ImagiChem: Hybrid Deterministic Image-Conditioned Generation of Chemically Valid and Drug-like Molecules from Artistic Inputs
  3. Sustainable Xanthine-Grafted Alginate Biosensing Platform for Metabolic Disorder Diagnostics
  4. A Reproducible Hierarchical Virtual Screening Framework Integrating Scaffold-Aware Machine Learning, Ensemble Docking, and Molecular Dynamics: Application to IDO1
  5. Structure-Guided Repurposing of Approved Drugs Identifies Aprepitant and Mavorixafor as Putative δ-Opioid Receptor Agonist Candidates
  6. Multifunctional Halloysite-Glutathione Nanocomposite for Solar CO2 Conversion and Pollutant Sensing
  7. Repurposing FDA-approved drugs as SIRT3-binding candidates for Ataxia–Telangiectasia: An integrated virtual screening, molecular dynamics, and SPR study
  8. An Integrated in Silico and SPR-based Workflow Identifies FDA-Approved Drugs as Previously Unrecognized SIRT3 Binders
  9. Tunable phenolic-modified alginate–chitosan semi-IPNs as multifunctional platforms for localized antimicrobial and antioxidant therapy
  10. Targeting the untargetable: accelerated discovery of KRAS G12D inhibitors through a deep learning-enhanced in silico pipeline
  11. High-Throughput, High-Quality: Benchmarking GNINA and AutoDock Vina for Precision Virtual Screening Workflow
  12. Nanosensors Made of Halloysite and Kojic Acid Metal Complexes for Dopamine Detection
  13. Development of a γ-Cyclodextrin-Based Cryogel Loaded with Trimethoprim for Acne Treatment: Design, Synthesis, and In Vitro Evaluation
  14. High-Throughput, High-Quality: Unlocking GNINA for Precision Virtual Screening
  15. Designing a monolithic photo-Fenton catalyst using a fungal hydroxypyrone metabolic derivative
  16. Selective Control by Pistacia vera L. and Its Carotenoid Zeaxanthin on SARS-CoV-2 Virus
  17. Enhancing HDAC Inhibitor Screening: Addressing Zinc Parameterization and Ligand Protonation in Docking Studies
  18. A full carbon-based thermoplastic photocatalyst for organic pollutants abatement: An experimental and computational study
  19. Carboxylato-prism[6]arene as a supramolecular catalyst in water: exploiting its deep hydrophobic cavity for green oxidation of aromatic amines
  20. Enhancing HDAC Inhibitors Screening: Addressing Zinc Parameterization and Ligand Protonation in Docking Studies
  21. Design, Synthesis, and Evaluation of Novel (−)‐cis‐N‐Normetazocine Derivatives: In Vitro and Molecular Modeling Insights
  22. Developing Advanced Antibacterial Alginic Acid Biomaterials through Dual Functionalization
  23. Efficient green solvent-free CO2/epoxide cycloaddition catalyzed by a β-cyclodextrin-imidazolium-based ionic liquid
  24. Synthesis, Characterisation, and In Vitro Evaluation of Biocompatibility, Antibacterial and Antitumor Activity of Imidazolium Ionic Liquids
  25. Structural, morphological, and modeling studies of N-(benzoyloxy)benzamide as a specific inhibitor of Type II inosine monophosphate dehydrogenase
  26. CYP7B1 as a Biomarker for Prostate Cancer Risk and Progression: Metabolic and Oncogenic Signatures (Diagnostic Immunohistochemistry Analysis by Tissue Microarray in Prostate Cancer Patients—Diamond Study)
  27. Targeting Viral and Cellular Cysteine Proteases for Treatment of New Variants of SARS-CoV-2
  28. Rutin/Sulfobutylether-β-Cyclodextrin as a Promising Therapeutic Formulation for Ocular Infection
  29. Rutin/Sulfobutylether-β-Cyclodextrin as a Promising Therapeutic Formulation for Ocular Infection
  30. γ‐Cyclodextrins as Supramolecular Reactors for the Three‐component Aza‐Darzens Reaction in Water
  31. Supramolecular biomaterials as drug nanocontainers with iron depletion properties for antimicrobial applications
  32. Bio-Based Palladium Catalyst in Cryogel for Cross-Coupling Reactions
  33. An Integrated In Silico and In Vitro Approach for the Identification of Natural Products Active against SARS-CoV-2
  34. Discovery of first novel sigma/HDACi dual-ligands with a potent in vitro antiproliferative activity
  35. Antiviral Efficacy of Heparan Sulfate and Enoxaparin Sodium against SARS-CoV-2: An In-Vitro/in-Silico Model
  36. HEMA-based macro and microporous materials for CO2 capture
  37. Insights into the Friedel–Crafts Benzoylation of N-Methylpyrrole inside the Confined Space of the Self-Assembled Resorcinarene Capsule
  38. How can artificial intelligence be utilized for de novo drug design against COVID-19 (SARS-CoV-2)?
  39. Total Bio-Based Material for Drug Delivery and Iron Chelation to Fight Cancer through Antimicrobial Activity
  40. Total Bio-Based Material To Fight Cancer Through Antimicrobial Activity
  41. Progress of the “Molecular Informatics” Section in 2022
  42. Selective noncovalent proteasome inhibiting activity of trifluoromethyl‐containing gem‐quaternary aziridines
  43. Computer-Assisted Design of Peptide-Based Radiotracers
  44. Steered Molecular Dynamics Simulations Study on FABP4 Inhibitors
  45. Design, synthesis, in vitro evaluation, and molecular modeling studies of N‐substituted benzomorphans, analogs of LP2, as novel MOR ligands
  46. Heparan Sulfate and Enoxaparin Interact at the Interface of the Spike Protein of HCoV-229E but Not with HCoV-OC43
  47. Portable Nanocomposite System for Wound Healing in Space
  48. Soluble peptidoglycan fragments produced by Limosilactobacillus fermentum with antiproliferative activity are suitable for potential therapeutic development: A preliminary report
  49. 1,2-Dibenzoylhydrazine as a Multi-Inhibitor Compound: A Morphological and Docking Study
  50. Sponge-like macroporous cyclodextrin-based cryogels for controlled drug delivery
  51. CO2-derived non-isocyanate polyurethanes (NIPUs) and their potential applications
  52. Carbamoyl-Decorated Cyclodextrins for Carbon Dioxide Adsorption
  53. Cyclodextrin-Based Cryogels for Controlled Drug Delivery
  54. Novel Class of Proteasome Inhibitors: In Silico and In Vitro Evaluation of Diverse Chloro(trifluoromethyl)aziridines
  55. Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. An update from 2017 to early 2022
  56. Targeting the SARS-CoV-2 HR1 with Small Molecules as Inhibitors of the Fusion Process
  57. Correction to “Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents”
  58. Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia
  59. Artificial Intelligence Technologies for COVID-19 De Novo Drug Design
  60. Artificial Intelligence Technologies for COVID-19 De Novo Drug Design
  61. A sustainable porous composite material based on loofah-halloysite for gas adsorption and drug delivery
  62. Carbocation catalysis in confined space: activation of trityl chloride inside the hexameric resorcinarene capsule
  63. Supramolecular catalysis in confined space: making the pyrogallol[4]arene capsule catalytically active in non-competitive solvent
  64. Green Efficient One-Pot Synthesis and Separation of Nitrones in Water Assisted by a Self-Assembled Nanoreactor
  65. Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties
  66. From Far West to East: Joining the Molecular Architecture of Imidazole-like Ligands in HO-1 Complexes
  67. Natural Substances in the Fight of SARS-CoV-2: A Critical Evaluation Resulting from the Cross-Fertilization of Molecular Modeling Data with the Pharmacological Aspects
  68. Growing the molecular architecture of imidazole-like ligands in HO-1 complexes
  69. Synthesis and in vitro evaluation of chlorogenic acid amides as potential hypoglycemic agents and their synergistic effect with acarbose
  70. Unusual Calixarenes Incorporating Chromene and Benzofuran Moieties Obtained via Propargyl Claisen Rearrangement
  71. Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent In Vitro Antiproliferative Activity
  72. Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents
  73. Shedding Light on the Chemistry and the Properties of Münchnone Functionalized Graphene
  74. Expanding Coefficient: A Parameter To Assess the Stability of Induced-Fit Complexes
  75. Pseudo-Dipeptide Bearing α,α-Difluoromethyl Ketone Moiety as Electrophilic Warhead with Activity against Coronaviruses
  76. Nanosponges based on self-assembled starfish-shaped cucurbit[6]urils functionalized with imidazolium arms
  77. An Integrated Pharmacophore/Docking/3D-QSAR Approach to Screening a Large Library of Products in Search of Future Botulinum Neurotoxin A Inhibitors
  78. Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region
  79. A Rare Natural Benzo[k,l]xanthene as a Turn-Off Fluorescent Sensor for Cu2+ Ion
  80. New Anti SARS-Cov-2 Targets for Quinoline Derivatives Chloroquine and Hydroxychloroquine
  81. Functionalization of Single and Multi-Walled Carbon Nanotubes with Polypropylene Glycol Decorated Pyrrole for the Development of Doxorubicin Nano-Conveyors for Cancer Drug Delivery
  82. Putative Inhibitors of SARS-CoV-2 Main Protease from A Library of Marine Natural Products: A Virtual Screening and Molecular Modeling Study
  83. Sigma Receptor Ligands Carrying a Nitric Oxide Donor Nitrate Moiety: Synthesis, In Silico, and Biological Evaluation
  84. Inhibitors of SARS-CoV-2 Main Protease from a Library of Marine Natural Products: A Virtual Screening and Molecular Modeling Study
  85. New Arylethanolimidazole Derivatives as HO-1 Inhibitors with Cytotoxicity against MCF-7 Breast Cancer Cells
  86. Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers
  87. Cucurbit[7]uril as a catalytic nanoreactor for one-pot synthesis of isoxazolidines in water
  88. Repurposing of FDA‐Approved Drugs for Treating Iatrogenic Botulism: A Paired 3D‐QSAR/Docking Approach†
  89. Progress in the development of more effective and safer analgesics for pain management
  90. [1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor
  91. Synergic Interplay Between Halogen Bonding and Hydrogen Bonding in the Activation of a Neutral Substrate in a Nanoconfined Space
  92. Synergic Interplay Between Halogen Bonding and Hydrogen Bonding in the Activation of a Neutral Substrate in a Nanoconfined Space
  93. Supramolecular host-guest interactions of pseudoginsenoside F11 with β- and γ-cyclodextrin: Spectroscopic/spectrometric and computational studies
  94. Computational Tools in the Discovery of FABP4 Ligands: A Statistical and Molecular Modeling Approach
  95. Physicochemical Characterization and Antioxidant Activity Evaluation of Idebenone/Hydroxypropyl-β-Cyclodextrin Inclusion Complex †
  96. Computational Tools in the Discovery of FABP4 Ligands: A Statistical and Molecular Modeling Approach
  97. Metabolic Characterization of Supernatants Produced by Lactobacillus spp. With in vitro Anti-Legionella Activity
  98. Structure-Based Approach for the Prediction of Mu-opioid Binding Affinity of Unclassified Designer Fentanyl-Like Molecules
  99. A molecular hybrid producing simultaneously singlet oxygen and nitric oxide by single photon excitation with green light
  100. Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application
  101. 3D-QSAR assisted identification of FABP4 inhibitors: An effective scaffold hopping analysis/QSAR evaluation
  102. Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Bearing a Pyrazole Scaffold and a Cinnamoyl Linker
  103. Synthesis of Rosmarinic Acid Amides as Antioxidative and Hypoglycemic Agents
  104. Fourfold Filtered Statistical/Computational Approach for the Identification of Imidazole Compounds as HO-1 Inhibitors from Natural Products
  105. FABP4 inhibitors 3D-QSAR model and isosteric replacement of BMS309403 datasets
  106. Gemcitabine anticancer activity enhancement by water soluble celecoxib/sulfobutyl ether-β-cyclodextrin inclusion complex
  107. Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands
  108. A hexameric resorcinarene capsule as a hydrogen bonding catalyst in the conjugate addition of pyrroles and indoles to nitroalkenes
  109. Metyrapone-β-cyclodextrin supramolecular interactions inferred by complementary spectroscopic/spectrometric and computational studies
  110. A Pseudouridine Isoxazolidinyl Nucleoside Analogue Structural Analysis: A Morphological Approach
  111. Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis
  112. A Structure- and Ligand-Based Virtual Screening of a Database of “Small” Marine Natural Products for the Identification of “Blue” Sigma-2 Receptor Ligands
  113. Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines
  114. Discovery of High-Affinity Cannabinoid Receptors Ligands through a 3D-QSAR Ushered by Scaffold-Hopping Analysis
  115. PEGylate porphyrin-gold nanoparticles conjugates as removable pH-sensor nano-probes for acidic environments
  116. Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis
  117. Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D‐QSAR Coupled to Scaffold‐Hopping Analysis
  118. Novel Structural Insight into Inhibitors of Heme Oxygenase-1 (HO-1) by New Imidazole-Based Compounds: Biochemical and In Vitro Anticancer Activity Evaluation
  119. Light‐Controlled Simultaneous “On Demand” Release of Cytotoxic Combinations for Bimodal Killing of Cancer Cells
  120. Mild Friedel–Crafts Reactions inside a Hexameric Resorcinarene Capsule: C−Cl Bond Activation through Hydrogen Bonding to Bridging Water Molecules
  121. Mild Friedel–Crafts Reactions inside a Hexameric Resorcinarene Capsule: C−Cl Bond Activation through Hydrogen Bonding to Bridging Water Molecules
  122. Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors
  123. Covalently immobilized catalase on functionalized graphene: effect on the activity, immobilization efficiency, and tetramer stability
  124. DNA intercalators based on (1,10-phenanthrolin-2-yl)isoxazolidin-5-yl core with better growth inhibition and selectivity than cisplatin upon head and neck squamous cells carcinoma
  125. Bio-activated intramolecular anti-aza-Michael addition: stereoselective synthesis of hydantoin derivatives
  126. The hexameric resorcinarene capsule as an artificial enzyme: ruling the regio and stereochemistry of a 1,3-dipolar cycloaddition between nitrones and unsaturated aldehydes
  127. (+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties
  128. Recent advances in drug discovery of phototherapeutic non-porphyrinic anticancer agents
  129. Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors
  130. Serendipitous discovery of potent human head and neck squamous cell carcinoma anti-cancer molecules: A fortunate failure of a rational molecular design
  131. Ensemble-based ADME-Tox profiling and virtual screening for the discovery of new inhibitors of the Leishmania mexicana cysteine protease CPB2.8ΔCTE
  132. Molecular modeling studies of pseudouridine isoxazolidinyl nucleoside analogues as potential inhibitors of the pseudouridine 5ʹ-monophosphate glycosidase
  133. Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands
  134. Synthesis and evaluation of haloperidol metabolite II prodrugs as anticancer agents
  135. Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review
  136. Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors
  137. Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis
  138. Sigma-2 receptor ligands QSAR model dataset
  139. Repurposing of Human Kinase Inhibitors in Neglected Protozoan Diseases
  140. γ-Cyclodextrin as a Catalyst for the Synthesis of 2-Methyl-3,5-diarylisoxazolidines in Water
  141. The Search for Potent, Small-Molecule HDACIs in Cancer Treatment: A Decade After Vorinostat
  142. S2RSLDB: a comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands
  143. Antiangiogenic Effect of (±)-Haloperidol Metabolite II Valproate Ester [(±)-MRJF22] in Human Microvascular Retinal Endothelial Cells
  144. 5′-Spiro-cyclopropanated lactose derivatives as suitable intermediates for the chain elongation: synthesis of a new 6-deoxy-6-methyl δ-eptulose
  145. Synthesis and characterization of copolycarbonates having azobenzene units in the main chain as an active group for optical logic gate devices
  146. Targeting of the Leishmania mexicana cysteine protease CPB2.8ΔCTE by decorated fused benzo[b]thiophene scaffold
  147. Decorated 6,6′,7,7′-tetrahydro-1H,1′H-2,3′-biindole scaffold as promising candidate for recognition of the CDK2 allosteric site
  148. An α1-adrenergic receptor ligand repurposed as a potent antiproliferative agent for head and neck squamous cell carcinoma
  149. Haloperidol metabolite II prodrug: Asymmetric synthesis and biological evaluation on rat C6 glioma cells
  150. 4-Nitro-2,1,3-benzoxadiazole derivatives as potential fluorescent sigma receptor probes
  151. Repurposing of oxazolone chemistry: gaining access to functionalized graphene nanosheets in a top-down approach from graphite
  152. DNA Recognition with Polycyclic-Aromatic-Hydrocarbon-Presenting Calixarene Conjugates
  153. Production of filmable medium-chain-length polyhydroxyalkanoates produced from glycerol by Pseudomonas mediterranea
  154. Use of Microwave Heating in the Synthesis of Heterocycles from Carbohydrates
  155. Recent advances in small organic molecules as DNA intercalating agents: Synthesis, activity, and modeling
  156. A top–down approach to crystal engineering of a racemic Δ2-isoxazoline
  157. Functional hybrid co-crystals of humic substances: a growth forecast
  158. Prevalence of Oxetanose Forms in the Tautomeric Equilibrium of β-Hydroxy-1,5-dicarbonyl Monosaccharides
  159. Self-Catalyzed Mannich-Type Reaction of Enolizable Cyclic 1,3-Dicarbonyls to Acyclic Nitrones: An Entry to Functionalized β-Enamino Diones
  160. Phosphonated Nucleoside Analogues
  161. Experimental and in silico characterization of a biologically active inosose
  162. Crystal Morphologies and Polymorphs in Tolbutamide Microcrystalline Powder
  163. Histone Methyltransferase Inhibitors: Novel Epigenetic Agents for Cancer Treatment
  164. Histone Methyltransferase Inhibitors: Novel Epigenetic Agents for Cancer Treatment
  165. Synthesis and biological activity of novel bifunctional isoxazolidinyl polycyclic aromatic hydrocarbons
  166. Novel isoxazole polycyclic aromatic hydrocarbons as DNA-intercalating agents
  167. Potassium caffeate/caffeic acid co-crystal: the rat race between the catecholic and carboxylic moieties in an atypical co-crystal
  168. Recent Developments on Rotaxane-Based Shuttles: An Update to 2010
  169. How molecular interactions affect crystal morphology: The case of haloperidol
  170. Design, Synthesis, Molecular Docking and Crystal Structure Prediction of New Azasugar Analogues of α-Glucosidase Inhibitors
  171. From the X-rays to a reliable “low cost” computational structure of caffeic acid: DFT, MP2, HF and integrated molecular dynamics–X-ray diffraction approach to condensed phases
  172. An intriguing U-shaped molecule as possible ionophore for sensor applications: A computational DFT and NMR study
  173. Isoxazolidinyl polycyclic aromatic hydrocarbons as DNA-intercalating antitumor agents
  174. Stereodefined ring contraction-rearrangement of thiocoumarins to new fused benzo[b]thiophene derivatives
  175. β-Cyclodextrin and Caffeine Complexes with Natural Polyphenols from Olive and Olive Oils: NMR, Thermodynamic, and Molecular Modeling Studies
  176. Could N-(diethylcarbamothioyl)benzamide be a good ionophore for sensor membranes?
  177. Structural determinants of resveratrol for cell proliferation inhibition potency: Experimental and docking studies of new analogs
  178. Synthesis of C-4′Truncated Phosphonated Carbocyclic 2′-Oxa-3′-azanucleosides as Antiviral Agents
  179. Biomimetic Synthesis of Natural and “Unnatural” Lignans by Oxidative Coupling of Caffeic Esters
  180. Stereoselective Synthesis and Biological Evaluations of Novel 3′-Deoxy-4′-azaribonucleosides as Inhibitors of Hepatitis C Virus RNA Replication
  181. Structures and properties in different media of N,N-(diethylcarbamothioyl)furan-2-carboxamide: A ionophore for sensor membranes
  182. Recent Developments on Rotaxane-Based Shuttles
  183. 3-Amino-2(5H)furanones as inhibitors of subgenomic hepatitis C virus RNA replication
  184. Cyclopropanation of 5-methylene galactopyranosides by dihalo-, ethoxycarbonyl-, and unsubstituted carbenes
  185. Conversion of Oximes to Carbonyl Compounds by Triscetylpyridinium Tetrakis(oxodiperoxotungsto) Phosphate (PCWP)-mediated Oxidation with Hydrogen Peroxide
  186. Synthesis of Methyleneisoxazolidine Nucleoside Analogues by Microwave-Assisted Nitrone Cycloaddition
  187. Phosphonated Carbocyclic 2‘-Oxa-3‘-azanucleosides as New Antiretroviral Agents
  188. A Novel Class of Modified Nucleosides: Synthesis of Alkylidene Isoxazolidinyl Nucleosides Containing Thymine
  189. A DFT study on the 1,3-dipolar cycloaddition reactions of C-(hetaryl) nitrones with methyl acrylate and vinyl acetate
  190. Synthesis and biological evaluation of phosphonated carbocyclic 2′-oxa-3′-aza-nucleosides
  191. Binding of a non-ionic pyrenylisoxazolidine derivative to double-stranded polynucleotides: spectroscopic and molecular modelling studies
  192. Synthesis and Biological Activity of Isoxazolidinyl Polycyclic Aromatic Hydrocarbons:  Potential DNA Intercalators
  193. Corrigendum to “Enantioselective synthesis of N,O-psiconucleosides”
  194. Zinc(II) Triflate-Controlled 1,3-Dipolar Cycloadditions of C -(2-Thiazolyl)nitrones:  Application to the Synthesis of a Novel Isoxazolidinyl Analogue of Tiazofurin
  195. Synthesis of functionalized polyhedral oligomeric silsesquioxane (POSS) macromers by microwave assisted 1,3-dipolar cycloaddition
  196. From Amino Acids to Enantiopure Bicyclic Isoxazolidinylpyridin-4(1H)-ones through Intramolecular Nitrone Cycloadditions
  197. Synthesis of Phosphonated Carbocyclic 2‘-Oxa-3‘-aza-nucleosides:  Novel Inhibitors of Reverse Transcriptase
  198. Reactions of Benzonitrile Oxide with Methoxypyrimidines and Pyrimidones
  199. C-Alkoxycarbonyl Nitrones: Building Blocks for the Synthesis of Butenolides, Lactams and Modified Nucleosides
  200. Synthesis of pyrimidine-containing 3-aminobutenolides
  201. A DFT rationalization for the observed regiochemistry in the nitrile oxide cycloaddition with anthracene and acridine
  202. From cyclopentadiene to isoxazoline–carbocyclic nucleosides: a rapid access to biological molecules through nitrosocarbonyl chemistry
  203. Steric course of some cyclopropanation reactions of L-threo-hex-4-enopyranosides
  204. Diastereoselective synthesis of homo-N,O-nucleosides
  205. Diastereo- and Enantioselective Synthesis of 1′-C-BranchedN,O-Nucleosides
  206. Diastereo- and enantioselective synthesis of N,O-nucleosides
  207. Enantioselective synthesis of N,O-psiconucleosides
  208. Enantioselective Syntheses and Cytotoxicity ofN,O-Nucleosides
  209. Isoxazolidine analogues of pseudouridine: a new class of modified nucleosides
  210. A DFT study on the 1,3-dipolar cycloaddition reactions of C-(methoxycarbonyl)-N-methyl nitrone with methyl acrylate and vinyl acetate
  211. New Rearrangement of 4-Isoxazoline System:  Conversion of Ketones into α,β-Unsaturated Amides
  212. Enantioselective synthesis of isoxazolidinyl nucleosides containing uracil, 5-fluorouracil, thymine and cytosine as new potential anti-HIV drugs
  213. Syntheses of new chiral bicyclic sultams and their use as auxiliaries in asymmetric conjugate addition of Grignard reagents
  214. Intramolecular Cycloadditions of α-Allyloxycarbonylnitrones:  Stereoselective Synthesis of 3-Amino-2(5H)furanones
  215. Diastereoselective Synthesis ofN,O-Psiconucleosides, a New Class of Modified Nucleosides
  216. Enantioselective synthesis of 4-hydroxy-d-pyroglutamic acid derivatives by an asymmetric 1,3-dipolar cycloaddition
  217. Modified nucleosides. A general and diastereoselective approach to N,O-psiconucleosides
  218. A Stereoselective Approach to Isoxazolidinyl Nucleosides
  219. Stereoselective synthesis of homochiral annulated sultams via intramolecular cycloaddition reactions
  220. Diastereoselective synthesis of N,O-psiconucleosides via 1,3-dipolar cycloadditions
  221. Diastereoselective and enantioselective synthesis of 4′-aza analogues of 2′,3′-dideoxynucleosides
  222. Cycloadditions of mesitonitrile oxide with amino- and nitrostilbenes†
  223. An Unusual Route for the Regioselective Acylation of Polycyclic Aromatic Hydrocarbons: Nitrile Oxide Addition Followed by Isoxazoline Degradation
  224. Homochiral α-d- and β-d-Isoxazolidinylthymidines via 1,3-Dipolar Cycloaddition†
  225. Stereoselective Synthesis of Enantiomerically Pure Isoxa-zolidine-fused d-Lactams
  226. Stereoselective Synthesis of 2‘-Amino-2‘,3‘-dideoxynucleosides by Nitrone 1,3-Dipolar Cycloaddition:  A New Efficient Entry Toward d4T and Its 2-Methyl Analogue †
  227. Cycloaddition of nitrile oxides to aza-analogues of phenanthrene
  228. A general synthetic approach to 5-alkyl-2(5H)furanonesvia 1,3-dipolar cycloaddition
  229. THE REACTION OF UNSATURATED CARBONYL COMPOUNDS WITH "ACTIVATED" SULFUR PART 3.1 REACTION COURSE
  230. The Reaction of Unsaturated Carbonyl Compounds with “Activated” Sulfur. Part 3.1Reaction Course
  231. The Reaction of Unsaturated Carbonyl Compounds with "Activated" Sulfur (II). Formation of Cyclic Disulfide and Polysulfides
  232. Cycloadditions of Mesitonitrile Oxide with Hydroxy- and Methoxy-substituted Stilbenes. A Directing Hydrogen Bonding Model
  233. Biomimetic Supramolecular Biophenol−Carbohydrate and Biophenol−Protein Models by NMR Experiments
  234. Stereoselective synthesis of isoxazole and pyrazole annulated sultams via intramolecular 1,3-dipolar cycloaddition reactions
  235. Intramolecular nitrone cycloaddition: Stereoselective synthesis of piperidine systems
  236. Intramolecular nitrile oxide cycloaddition (INOC) of substituted amido-oximes
  237. An asymmetric approach to pyrrolidinone and pyrrolizidinone systems by intramolecular oxime-olefin cycloaddition
  238. Modified dideoxynucleosides: Synthesis of 2′-N-alkyl-3′-hydroxyalkyl-1′,2′-isoxazolidinyl thymidine and 5-fluorouridine derivatives
  239. Synthesis of 1-alkyl-3-dialkylaminoalkylamine[1]benzo-thieno[2,3-b]pyrazin-2(1H))-ones and their ability to antagonize KCl-induced contractions
  240. Ring opening of the isoxazolidine system: A new synthesis of 3-amino-2(5H)furanones
  241. α-Amino acids as chiral educts for stereoselective syntheses of pyrrolidine and pyrrolizidine systems
  242. Ring-opening of isoxazolidine nucleus: Competitive formation of α,β-enones and tetrahydro-1,3-oxazines
  243. Stereoselective synthesis of fused γ-lactams by intramolecular nitrone cycloaddition
  244. Stereoselective control in 1,3-dipolar cycloaddition of nitrones to substituted styrenes
  245. The Reaction of Unsaturated Carbonyl Compounds with "Activated" Sulfur
  246. Functionalized g-Lactones via Intramolecular Nitrile Oxide Cycloaddition
  247. A New Synthesis of Streptomyces Lactones by 1,3-Dipolar Cycloaddition
  248. Ring-Opening of 4-Isoxazolines: Competitive Formation of Enamino Derivatives and a,b-Enones
  249. Formation of Isoxazolines and Isoxazoles Via Dipolar Cycloaddition by Catalytic Oxidation of Aldoximes with Hydrogen Peroxide and W(Vi) Peroxo Complexes
  250. Novel approach to the ring-opening of 4-isoxazolines: One-pot synthesis of α,β-enones
  251. One-flask transformation of secondary amines to nitrones by oxidation with hydrogen peroxide mediated by triscetylpyridinium tetrakis oxodiperoxotungsto-phosphate (PCWP). Some mechanistic considerations
  252. Rearrangement of o-alkynyl substituted α-diazoacetophenones. Conversion to β-naphthols via arylketene intermediates