All Stories

  1. Reducing insulin via conditional partial gene ablation in adults reverses diet-induced weight gain

    Article • The FASEB Journal, March 2018, Federation of American Societies For Experimental Biology (FASEB)

    Professor Corey Nislow, Søs Skovsø

  2. Faculty Opinions recommendation of Selection of chromosomal DNA libraries using a multiplex CRISPR system.

    Article • September 2014, F1000Research

    Professor Corey Nislow

  3. The Yeast Deletion Collection: A Decade of Functional Genomics

    Article • Genetics, June 2014, Genetics Society of America

    Professor Corey Nislow

  4. Sequencing and functional analysis of the genome of a nematode egg-parasitic fungus, Pochonia chlamydosporia

    Article • Fungal Genetics and Biology, April 2014, Elsevier

    Professor Corey Nislow

  5. Large-Scale Identification and Analysis of Suppressive Drug Interactions

    Article • Chemistry & Biology, April 2014, Elsevier

    Professor Corey Nislow

  6. GC-Rich DNA Elements Enable Replication Origin Activity in the Methylotrophic Yeast Pichia pastoris

    Article • PLoS Genetics, March 2014, PLOS

    Professor Corey Nislow

  7. CHIP-MYTH: A novel interactive proteomics method for the assessment of agonist-dependent interactions of the human β2-adrenergic receptor

    Article • Biochemical and Biophysical Research Communications, March 2014, Elsevier

    Professor Corey Nislow

  8. Broad metabolic sensitivity profiling of a prototrophic yeast deletion collection

    Article • Genome Biology, January 2014, Springer Science + Business Media

    Professor Corey Nislow

  9. A genome scale overexpression screen to reveal drug activity in human cells

    Article • Genome Medicine, January 2014, Springer Science + Business Media

    Professor Corey Nislow

  10. PITPs as targets for selectively interfering with phosphoinositide signaling in cells

    Article • Nature Chemical Biology, November 2013, Springer Science + Business Media

    Professor Corey Nislow

  11. Conserved Substitution Patterns around Nucleosome Footprints in Eukaryotes and Archaea Derive from Frequent Nucleosome Repositioning through Evolution

    Article • PLoS Computational Biology, November 2013, PLOS

    Professor Corey Nislow

  12. A unified model for yeast transcript definition

    Article • Genome Research, October 2013, Cold Spring Harbor Laboratory Press

    Professor Corey Nislow

  13. A Novel Small Molecule Methyltransferase Is Important for Virulence in Candida albicans

    Article • ACS Chemical Biology, October 2013, American Chemical Society (ACS)

    Professor Corey Nislow

  14. Whole Genome Duplication and Enrichment of Metal Cation Transporters Revealed by De Novo Genome Sequencing of Extremely Halotolerant Black Yeast Hortaea werneckii

    Article • PLoS ONE, August 2013, PLOS

    Professor Corey Nislow, Mr Shaun Dunn Jackman

  15. A High-Throughput Yeast Assay Identifies Synergistic Drug Combinations

    Article • Assay and Drug Development Technologies, June 2013, Mary Ann Liebert Inc

    Professor Corey Nislow

  16. A Compendium of Nucleosome and Transcript Profiles Reveals Determinants of Chromatin Architecture and Transcription

    Article • PLoS Genetics, May 2013, PLOS

    Professor Corey Nislow

  17. DNA-Damaging Agents in Cancer Chemotherapy: Serendipity and Chemical Biology

    Article • Chemistry & Biology, May 2013, Elsevier

    Professor Corey Nislow

  18. Genetic and Genomic Architecture of the Evolution of Resistance to Antifungal Drug Combinations

    Article • PLoS Genetics, April 2013, PLOS

    Professor Corey Nislow

  19. Faculty Opinions recommendation of Decoupling epigenetic and genetic effects through systematic analysis of gene position.

    Article • January 2013, F1000Research

    Professor Corey Nislow

  20. Chemogenomic Profiling

    Article • January 2013, Elsevier

    Professor Gary D Bader, Professor Corey Nislow

  21. Chromatin is an ancient innovation conserved between Archaea and Eukarya

    Article • eLife, December 2012, eLife

    Professor Gary D Bader, Professor Corey Nislow

  22. Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors

    Article • Journal of Clinical Investigation, December 2012, American Society for Clinical Investigation

    Professor Corey Nislow

  23. Timing of Transcriptional Quiescence during Gametogenesis Is Controlled by Global Histone H3K4 Demethylation

    Article • Developmental Cell, November 2012, Elsevier

    Professor Corey Nislow

  24. Faculty Opinions recommendation of One-step purification of assembly-competent tubulin from diverse eukaryotic sources.

    Article • October 2012, F1000Research

    Professor Corey Nislow

  25. An algorithm for chemical genomic profiling that minimizes batch effects: bucket evaluations

    Article • BMC Bioinformatics, September 2012, Springer Science + Business Media

    Professor Corey Nislow

  26. Comparative Chemogenomics To Examine the Mechanism of Action of DNA-Targeted Platinum-Acridine Anticancer Agents

    Article • ACS Chemical Biology, September 2012, American Chemical Society (ACS)

    Professor Corey Nislow

  27. Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress

    Article • Nature Cell Biology, July 2012, Springer Science + Business Media

    Professor Corey Nislow

  28. Faculty Opinions recommendation of A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target.

    Article • July 2012, F1000Research

    Professor Corey Nislow

  29. Identification of yeast genes that confer resistance to chitosan oligosaccharide (COS) using chemogenomics

    Article • BMC Genomics, June 2012, Springer Science + Business Media

    Professor Corey Nislow

  30. Faculty Opinions recommendation of Manipulating nucleosome disfavoring sequences allows fine-tune regulation of gene expression in yeast.

    Article • June 2012, F1000Research

    Professor Corey Nislow

  31. Genome Sequence of Shigella flexneri Serotype 5a Strain M90T Sm

    Article • Journal of Bacteriology, May 2012, ASM Journals

    Professor Corey Nislow

  32. Faculty Opinions recommendation of Whole lifespan microscopic observation of budding yeast aging through a microfluidic dissection platform.

    Article • March 2012, F1000Research

    Professor Corey Nislow

  33. Faculty Opinions recommendation of A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells.

    Article • March 2012, F1000Research

    Professor Corey Nislow

  34. Erratum: Corrigendum: Dafadine inhibits DAF-9 to promote dauer formation and longevity of Caenorhabditis elegans

    Article • Nature Chemical Biology, February 2012, Springer Science + Business Media

    Professor Corey Nislow

  35. Faculty Opinions recommendation of Parallel mapping and simultaneous sequencing reveals deletions in BCAN and FAM83H associated with discrete inherited disorders in a domestic dog breed.

    Article • February 2012, F1000Research

    Professor Corey Nislow

  36. Mitochondrial Electron Transport Is the Cellular Target of the Oncology Drug Elesclomol

    Article • PLoS ONE, January 2012, PLOS

    Professor Corey Nislow

  37. A novel calcineurin-independent activity of cyclosporin A in Saccharomyces cerevisiae

    Article • Molecular BioSystems, January 2012, Royal Society of Chemistry

    Professor Corey Nislow

  38. Barcode Sequencing for Understanding Drug–Gene Interactions

    Article • January 2012, Springer Science + Business Media

    Professor Corey Nislow

  39. A phenotypic screening platform to identify small molecule modulators of Chlamydomonas reinhardtii growth, motility and photosynthesis

    Article • Genome Biology, January 2012, Springer Science + Business Media

    Professor Corey Nislow

  40. Genome-wide analysis of intracellular pH reveals quantitative control of cell division rate by pHc in Saccharomyces cerevisiae

    Article • Genome Biology, January 2012, Springer Science + Business Media

    Professor Corey Nislow

  41. Faculty Opinions recommendation of Comprehensive genome-wide protein-DNA interactions detected at single-nucleotide resolution.

    Article • December 2011, F1000Research

    Professor Corey Nislow

  42. Bugs, drugs and chemical genomics

    Article • Nature Chemical Biology, December 2011, Springer Science + Business Media

    Professor Corey Nislow

  43. Genomic Approaches for Determining Nucleosome Occupancy in Yeast

    Article • November 2011, Springer Science + Business Media

    Professor Corey Nislow

  44. Multiple Means to the Same End: The Genetic Basis of Acquired Stress Resistance in Yeast

    Article • PLoS Genetics, November 2011, PLOS

    Professor Corey Nislow

  45. Dafadine inhibits DAF-9 to promote dauer formation and longevity of Caenorhabditis elegans

    Article • Nature Chemical Biology, November 2011, Springer Science + Business Media

    Professor Corey Nislow

  46. Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia

    Article • Cancer Cell, November 2011, Elsevier

    Professor Corey Nislow

  47. A Systems Biology Approach Reveals the Role of a Novel Methyltransferase in Response to Chemical Stress and Lipid Homeostasis

    Article • PLoS Genetics, October 2011, PLOS

    Professor Corey Nislow

  48. Compound Prioritization Methods Increase Rates of Chemical Probe Discovery in Model Organisms

    Article • Chemistry & Biology, October 2011, Elsevier

    Professor Gary D Bader, Professor Corey Nislow

  49. Nucleosome-coupled expression differences in closely-related species

    Article • BMC Genomics, September 2011, Springer Science + Business Media

    Professor Corey Nislow

  50. Curcumin Inhibits Growth of Saccharomyces cerevisiae through Iron Chelation

    Article • Eukaryotic Cell, September 2011, ASM Journals

    Professor Corey Nislow

  51. New azole antifungal agents with novel modes of action: Synthesis and biological studies of new tridentate ligands based on pyrazole and triazole

    Article • European Journal of Medicinal Chemistry, September 2011, Elsevier

    Professor Corey Nislow

  52. Competitive Genomic Screens of Barcoded Yeast Libraries

    Article • Journal of Visualized Experiments, August 2011, MyJove Corporation

    Professor Corey Nislow

  53. Response to “The Reality of Pervasive Transcription”

    Article • PLoS Biology, July 2011, PLOS

    Professor Corey Nislow

  54. Design, Synthesis and Characterization of a Highly Effective Inhibitor for Analog-Sensitive (as) Kinases

    Article • PLoS ONE, June 2011, PLOS

    Professor Morten Grötli, Professor Corey Nislow

  55. Design, Synthesis, and Characterization of a Highly Effective Hog1 Inhibitor: A Powerful Tool for Analyzing MAP Kinase Signaling in Yeast

    Article • PLoS ONE, May 2011, PLOS

    Professor Morten Grötli, Professor Corey Nislow, Professor Markus J Tamas

  56. Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell

    Article • Nature Biotechnology, May 2011, Springer Science + Business Media

    Professor Corey Nislow

  57. A comprehensive platform for highly multiplexed mammalian functional genetic screens

    Article • BMC Genomics, May 2011, Springer Science + Business Media

    Professor Corey Nislow

  58. The SWI/SNF complex acts to constrain distribution of the centromeric histone variant Cse4

    Article • The EMBO Journal, April 2011, Wiley

    Professor Corey Nislow, Professor Geoff Barton

  59. Systematic exploration of essential yeast gene function with temperature-sensitive mutants

    Article • Nature Biotechnology, March 2011, Springer Science + Business Media

    Professor Corey Nislow

  60. Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selection

    Article • Nature Methods, January 2011, Springer Science + Business Media

    Professor Corey Nislow

  61. Displaying Chemical Information on a Biological Network Using Cytoscape

    Article • January 2011, Springer Science + Business Media

    Professor Gary D Bader, Professor Corey Nislow

  62. Signature-tagged Mutagenesis to Characterize Genes Through Competitive Selection of Bar-coded Genome Libraries

    Article • January 2011, Springer Science + Business Media

    Professor Corey Nislow

  63. The Automated Cell: Compound and Environment Screening System (ACCESS) for Chemogenomic Screening

    Article • January 2011, Springer Science + Business Media

    Professor Corey Nislow

  64. The synthetic genetic interaction network reveals small molecules that target specific pathways in Sacchromyces cerevisiae

    Article • Molecular BioSystems, January 2011, Royal Society of Chemistry

    Professor Corey Nislow

  65. Endosomal protein sorting and autophagy genes contribute to the regulation of yeast life span

    Article • Autophagy, November 2010, Taylor & Francis

    Professor Corey Nislow

  66. Gene Annotation and Drug Target Discovery in Candida albicans with a Tagged Transposon Mutant Collection

    Article • PLoS Pathogens, October 2010, PLOS

    Professor Corey Nislow

  67. Diversity of Eukaryotic DNA Replication Origins Revealed by Genome-Wide Analysis of Chromatin Structure

    Article • PLoS Genetics, September 2010, PLOS

    Professor Corey Nislow

  68. A survey of yeast genomic assays for drug and target discovery

    Article • Pharmacology & Therapeutics, August 2010, Elsevier

    Professor Corey Nislow

  69. Genome-Wide Screen in Saccharomyces cerevisiae Identifies Vacuolar Protein Sorting, Autophagy, Biosynthetic, and tRNA Methylation Genes Involved in Life Span Regulation

    Article • PLoS Genetics, July 2010, PLOS

    Professor Corey Nislow

  70. A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans

    Article • Nature Chemical Biology, May 2010, Springer Science + Business Media

    Professor Gary D Bader, Professor Corey Nislow

  71. Most “Dark Matter” Transcripts Are Associated With Known Genes

    Article • PLoS Biology, May 2010, PLOS

    Professor Corey Nislow

  72. Recent advances and method development for drug target identification

    Article • Trends in Pharmacological Sciences, February 2010, Elsevier

    Professor Corey Nislow

  73. Exploring Gene Function and Drug Action Using Chemogenomic Dosage Assays

    Article • January 2010, Elsevier

    Professor Corey Nislow

  74. Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action

    Article • Genome Biology, January 2010, Springer Science + Business Media

    Professor Corey Nislow

  75. You too can play with an edge

    Article • Nature Methods, November 2009, Springer Science + Business Media

    Professor Corey Nislow

  76. A comparative analysis of DNA barcode microarray feature size

    Article • BMC Genomics, October 2009, Springer Science + Business Media

    Professor Corey Nislow

  77. Two-Color Cell Array Screen Reveals Interdependent Roles for Histone Chaperones and a Chromatin Boundary Regulator in Histone Gene Repression

    Article • Molecular Cell, August 2009, Elsevier

    Professor Corey Nislow

  78. Quantitative phenotyping via deep barcode sequencing

    Article • Genome Research, July 2009, Cold Spring Harbor Laboratory Press

    Professor Corey Nislow

  79. Alternative Splicing of PTC7 in Saccharomyces cerevisiae Determines Protein Localization

    Article • Genetics, June 2009, Genetics Society of America

    Professor Corey Nislow

  80. Self-reporting cells

    Article • BioTechniques, April 2009, Future Science

    Professor Corey Nislow

  81. A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds

    Article • Nature Biotechnology, April 2009, Springer Science + Business Media

    Professor Corey Nislow

  82. Precise Gene-Dose Alleles for Chemical Genetics

    Article • Genetics, March 2009, Genetics Society of America

    Professor Corey Nislow

  83. Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae

    Article • BMC Genomics, March 2009, Springer Science + Business Media

    Professor Corey Nislow, Professor Adam P Arkin

  84. Computationally Driven, Quantitative Experiments Discover Genes Required for Mitochondrial Biogenesis

    Article • PLoS Genetics, March 2009, PLOS

    Professor Corey Nislow

  85. Knocking sense into regulatory pathways

    Article • Nature Biotechnology, February 2009, Springer Science + Business Media

    Professor Corey Nislow

  86. Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis

    Article • BMC Microbiology, January 2009, Springer Science + Business Media

    Professor Corey Nislow

  87. Chemogenomic Approaches to Elucidation of Gene Function and Genetic Pathways

    Article • January 2009, Springer Science + Business Media

    Professor Corey Nislow

  88. A Library of Yeast Transcription Factor Motifs Reveals a Widespread Function for Rsc3 in Targeting Nucleosome Exclusion at Promoters

    Article • Molecular Cell, December 2008, Elsevier

    Professor Corey Nislow

  89. Chemical–Genetic Profiling of Imidazo[1,2-a]pyridines and -Pyrimidines Reveals Target Pathways Conserved between Yeast and Human Cells

    Article • PLoS Genetics, November 2008, PLOS

    Professor Corey Nislow, Dr Brahim El Bali

  90. Combination chemical genetics

    Article • Nature Chemical Biology, October 2008, Springer Science + Business Media

    Professor Corey Nislow

  91. Yeast chemical genomics and drug discovery: an update

    Article • Trends in Pharmacological Sciences, October 2008, Elsevier

    Professor Corey Nislow

  92. Erratum: Corrigendum: An integrated platform of genomic assays reveals small-molecule bioactivities

    Article • Nature Chemical Biology, October 2008, Springer Science + Business Media

    Professor Corey Nislow, Dr CHAO ZHANG

  93. Off-Target Effects of Psychoactive Drugs Revealed by Genome-Wide Assays in Yeast

    Article • PLoS Genetics, August 2008, PLOS

    Professor Corey Nislow

  94. An integrated platform of genomic assays reveals small-molecule bioactivities

    Article • Nature Chemical Biology, July 2008, Springer Science + Business Media

    Professor Corey Nislow, Dr CHAO ZHANG

  95. Yeast Barcoders: a chemogenomic application of a universal donor-strain collection carrying bar-code identifiers

    Article • Nature Methods, July 2008, Springer Science + Business Media

    Professor Corey Nislow

  96. Correction: Identification of Small Molecule Inhibitors of Pseudomonas aeruginosa Exoenzyme S Using a Yeast Phenotypic Screen

    Article • PLoS Genetics, April 2008, PLOS

    Professor Corey Nislow

  97. Identification of Small Molecule Inhibitors of Pseudomonas aeruginosa Exoenzyme S Using a Yeast Phenotypic Screen

    Article • PLoS Genetics, February 2008, PLOS

    Professor Corey Nislow

  98. Genome-wide analysis of barcoded Saccharomyces cerevisiae gene-deletion mutants in pooled cultures

    Article • Nature Protocols, November 2007, Springer Science + Business Media

    Professor Corey Nislow

  99. A high-resolution atlas of nucleosome occupancy in yeast

    Article • Nature Genetics, September 2007, Springer Science + Business Media

    Professor Corey Nislow

  100. Accelerating the Discovery of Biologically Active Small Molecules Using a High-Throughput Yeast Halo Assay

    Article • Journal of Natural Products, February 2007, American Chemical Society (ACS)

    Professor Corey Nislow

  101. Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions

    Article • Nature Genetics, January 2007, Springer Science + Business Media

    Professor Corey Nislow

  102. 17 Chemical Genomic Tools for Understanding Gene Function and Drug Action

    Article • January 2007, Elsevier

    Professor Corey Nislow

  103. Chemical Genomic Profiling for Identifying Intracellular Targets of Toxicants Producing Parkinson's Disease

    Article • Toxicological Sciences, October 2006, Oxford University Press (OUP)

    Professor Corey Nislow

  104. Experimental approaches to identify genetic networks

    Article • Current Opinion in Biotechnology, October 2006, Elsevier

    Professor Corey Nislow

  105. A unique and universal molecular barcode array

    Article • Nature Methods, July 2006, Springer Science + Business Media

    Professor Corey Nislow

  106. Introns Regulate RNA and Protein Abundance in Yeast

    Article • Genetics, July 2006, Genetics Society of America

    Professor Corey Nislow

  107. Genome-Wide Requirements for Resistance to Functionally Distinct DNA-Damaging Agents

    Article • PLoS Genetics, August 2005, PLOS

    Professor Corey Nislow, Professor Adam P Arkin

  108. ‘Chemogenomics: tools for protein families’ and ‘Chemical genomics: chemical and biological integration’

    Article • Pharmacogenomics, January 2003, Future Medicine

    Professor Corey Nislow

  109. SET1, A Yeast Member of the Trithorax Family, Functions in Transcriptional Silencing and Diverse Cellular Processes

    Article • Molecular Biology of the Cell, December 1997, American Society for Cell Biology (ASCB)

    Professor Corey Nislow

  110. Microtubule Dynamics and Chromosome Movement

    Article • January 1995, Springer Science + Business Media

    Professor Corey Nislow

  111. A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles

    Article • Nature, October 1992, Springer Science + Business Media

    Professor Corey Nislow

  112. Molecular components of the mitotic spindle

    Article • BioEssays, February 1992, Wiley

    Professor Corey Nislow

  113. A monoclonal antibody to a mitotic microtubule-associated protein blocks mitotic progression

    Article • The Journal of Cell Biology, August 1990, Rockefeller University Press

    Professor Corey Nislow

  114. Regionalized Cell Division during Sea Urchin Gastrulation Contributes to Archenteron Formation and Is Correlated with the Establishment of Larval Symmetry. (sea urchin/gastrulation/cell division/autoradiography)

    Article • Development Growth & Differentiation, October 1988, Wiley

    Professor Corey Nislow

  115. The origin of skeleton forming cells in the sea urchin embryo

    Article • January 1988

    Professor Corey Nislow

  116. Chemical-genetic approaches for exploring the mode of action of natural products

    Article • Springer Science + Business Media

    Professor Corey Nislow