All Stories

  1. Development of a genetic priority score to predict drug side effects using human genetic evidence
  2. Genetic analyses of eight complex diseases using predicted continuous representations of disease
  3. Evaluation of a machine learning-based metabolic marker for coronary artery disease in the UK Biobank
  4. Expanding drug targets for 112 chronic diseases using a machine learning-assisted genetic priority score
  5. Exome sequence analysis identifies rare coding variants associated with a machine learning-based marker for coronary artery disease
  6. Genome-first evaluation with exome sequence and clinical data uncovers underdiagnosed genetic disorders in a large healthcare system
  7. Muesli Intake May Protect Against Coronary Artery Disease
  8. Development of a human genetics-guided priority score for 19,365 genes and 399 drug indications
  9. In vitro and in vivo pharmacokinetic characterization, chiral conversion and PBPK scaling towards human PK simulation of S-MRI-1867, a drug candidate for Hermansky-Pudlak syndrome pulmonary fibrosis
  10. Abstract P1179: Evaluation Of A Machine Learning-based Metabolic Marker For Coronary Artery Disease In The UK Biobank
  11. A machine learning model identifies patients in need of autoimmune disease testing using electronic health records
  12. Machine Learning Identifies Plasma Metabolites Associated With Heart Failure in Underrepresented Populations With the TTR V122I Variant
  13. An Integrative Multiomics Framework for Identification of Therapeutic Targets in Pulmonary Fibrosis
  14. Phenome-wide Mendelian Randomization of Triglycerides and 2600 Diseases
  15. Machine learning-based marker for coronary artery disease: derivation and validation in two longitudinal cohorts
  16. Short-term prediction of coronary artery disease using serum metabolomic patterns
  17. Phenome-wide Mendelian randomization study of plasma triglycerides and 2,600 disease traits
  18. Peripheral Hybrid CB1R and iNOS Antagonist MRI-1867 Displays Anti-Fibrotic Efficacy in Bleomycin-Induced Skin Fibrosis
  19. CB 1 R and iNOS are distinct players promoting pulmonary fibrosis in Hermansky–Pudlak syndrome
  20. The Heterogeneity of Lipid Metabolism in Cancer
  21. Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice
  22. Bleomycin Induces Drug Efflux in Lungs: A pitfall for Pharmacological Studies of Pulmonary Fibrosis
  23. Targeting Peripheral CB1 Receptors Reduces Ethanol Intake via a Gut-Brain Axis
  24. The Heterogeneity of Lipid Metabolism in Cancer
  25. Cannabinoid-1 receptor deletion in podocytes mitigates both glomerular and tubular dysfunction in a mouse model of diabetic nephropathy
  26. Network analyses identify liver‐specific targets for treating liver diseases
  27. Cannabinoid CB1 receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis
  28. Developmental Role of Macrophage Cannabinoid-1 Receptor Signaling in Type 2 Diabetes
  29. Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer
  30. Hybrid inhibitor of peripheral cannabinoid-1 receptors and inducible nitric oxide synthase mitigates liver fibrosis
  31. Glucose-Independent Glutamine-Driven TCA Cycle in Cancer Cells
  32. Abstract 852: Novel role and mechanism of the LDHA protein as a survival factor for cancer cells.