All Stories

  1. Novel potent and selective dual acetylcholinesterase inhibitors: N-substituted theobromine and theophylline derivatives

    Article • RSC Medicinal Chemistry, January 2025, Royal Society of Chemistry

    Dr. María Isabel Rodríguez-Franco

  2. Target Fisher: A Consensus Structure‐Based Target Prediction Tool, and its Application in the Discovery of Selective MAO‐B Inhibitors

    Article • Chemistry - A European Journal, November 2024, Wiley

    Dr. María Isabel Rodríguez-Franco

  3. Discovery of a potent melatonin-based inhibitor of quinone reductase-2 with neuroprotective and neurogenic properties

    Article • European Journal of Medicinal Chemistry, November 2024, Elsevier

    Dr Martin Estrada Valencia, Dr. María Isabel Rodríguez-Franco

  4. 8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies

    Article • European Journal of Medicinal Chemistry, February 2023, Elsevier

    Dr. María Isabel Rodríguez-Franco, Dr Maria João Matos

  5. Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors

    Article • Journal of Medicinal Chemistry, October 2022, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  6. KEAP1‐NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential

    Article • Medicinal Research Reviews, September 2022, Wiley

    Dr. María Isabel Rodríguez-Franco

  7. An inhibitor of interaction between the transcription factor NRF2 and the E3 ubiquitin ligase adapter β-TrCP delivers anti-inflammatory responses in mouse liver

    Article • Redox Biology, September 2022, Elsevier

    Dr. María Isabel Rodríguez-Franco

  8. Antinociceptive and modulatory effect of pathoplastic changes in spinal glia of a TLR4/CD14 blocking molecule in two models of pain in rat

    Article • Biomedicine & Pharmacotherapy, June 2022, Elsevier

    Dr Ernesto Quesada, Dr. María Isabel Rodríguez-Franco

  9. Resveratrol-Based MTDLs to Stimulate Defensive and Regenerative Pathways and Block Early Events in Neurodegenerative Cascades

    Article • Journal of Medicinal Chemistry, March 2022, American Chemical Society (ACS)

    Dr Martin Estrada Valencia, Dr. María Isabel Rodríguez-Franco

  10. From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis

    Article • Journal of Medicinal Chemistry, May 2021, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  11. Synthesis and in vitro study of nitro- and methoxy-2-phenylbenzofurans as human monoamine oxidase inhibitors

    Article • Bioorganic Chemistry, February 2021, Elsevier

    Dr. María Isabel Rodríguez-Franco

  12. 2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreatitis

    Article • Journal of Medicinal Chemistry, August 2020, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  13. Optical control of muscular nicotinic channels with azocuroniums, photoswitchable azobenzenes bearing two N-methyl-N-carbocyclic quaternary ammonium groups

    Article • European Journal of Medicinal Chemistry, August 2020, Elsevier

    Dr Martin Estrada Valencia, Dr. María Isabel Rodríguez-Franco

  14. Identification of tetracyclic lactams as NMDA receptor antagonists with potential application in neurological disorders

    Article • European Journal of Medicinal Chemistry, May 2020, Elsevier

    Dr. María Isabel Rodríguez-Franco

  15. Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties

    Article • European Journal of Medicinal Chemistry, March 2020, Elsevier

    Dr Martin Estrada Valencia, Dr. María Isabel Rodríguez-Franco

  16. Structure-Activity Relationship of Potent Photo-Switchable Neuromuscular Inhibitors

    Article • Biophysical Journal, February 2019, Elsevier

    Dr Martin Estrada Valencia, Dr. María Isabel Rodríguez-Franco

  17. New flavonoid – N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer´s disease endowed with neurogenic properties

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, January 2019, Taylor & Francis

    Dr. María Isabel Rodríguez-Franco, Dr Jose A Morales-Garcia, Dr Martin Estrada Valencia

  18. Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors

    Article • European Journal of Medicinal Chemistry, October 2018, Elsevier

    Dr. María Isabel Rodríguez-Franco, Dr Martin Estrada Valencia, Professor Fernanda Borges

  19. Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease

    Article • European Journal of Medicinal Chemistry, August 2018, Elsevier

    Dr Martin Estrada Valencia, Dr. María Isabel Rodríguez-Franco

  20. The Melatonin Analog IQM316 May Induce Adult Hippocampal Neurogenesis and Preserve Recognition Memories in Mice

    Article • Cell Transplantation, March 2018, SAGE Publications

    Dr. María Isabel Rodríguez-Franco

  21. Functional Characterization of Novel Photo-Switchable Neuromuscular Blockers

    Article • Biophysical Journal, February 2018, Elsevier

    Dr Martin Estrada Valencia, Dr. María Isabel Rodríguez-Franco

  22. Poster Sessions Monday/Tuesday

    Article • Journal of Neurochemistry, August 2017, Wiley

    Dr. María Isabel Rodríguez-Franco

  23. The alkaloids of Banisteriopsis caapi, the plant source of the Amazonian hallucinogen Ayahuasca, stimulate adult neurogenesis in vitro

    Article • Scientific Reports, July 2017, Nature

    Dr. María Isabel Rodríguez-Franco

  24. Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia

    Article • European Journal of Medicinal Chemistry, April 2017, Elsevier

    Dr. María Isabel Rodríguez-Franco

  25. Optimization of Bicyclic Lactam Derivatives as NMDA Receptor Antagonists

    Article • ChemMedChem, March 2017, Wiley

    Dr. María Isabel Rodríguez-Franco

  26. New cinnamic – N-benzylpiperidine and cinnamic – N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties

    Article • European Journal of Medicinal Chemistry, October 2016, Elsevier

    Dr Jose A Morales-Garcia, Dr. María Isabel Rodríguez-Franco, Dr Martin Estrada Valencia

  27. Recent Advances in Neurogenic Small Molecules as Innovative Treatments for Neurodegenerative Diseases

    Article • Molecules, September 2016, MDPI AG

    Dr. María Isabel Rodríguez-Franco, Dr Martin Estrada Valencia

  28. New neurogenic lipoic-based hybrids as innovative Alzheimer's drugs with σ-1 agonism and β-secretase inhibition

    Article • Future Medicinal Chemistry, July 2016, Future Science

    Dr Jose A Morales-Garcia, Dr. María Isabel Rodríguez-Franco, Maurizio Romano, Dr Martin Estrada Valencia

  29. 3-Amidocoumarins as Potential Multifunctional Agents against Neurodegenerative Diseases

    Article • ChemMedChem, October 2015, Wiley

    Dr. María Isabel Rodríguez-Franco, Dr Maria João Matos, Dr Martin Estrada Valencia, Professor Fernanda Borges

  30. New coumarin-based fluorescent melatonin ligands. Design, synthesis and pharmacological characterization

    Article • European Journal of Medicinal Chemistry, October 2015, Elsevier

    Dr. María Isabel Rodríguez-Franco

  31. Poster Sessions Monday/Tuesday

    Article • Journal of Neurochemistry, August 2015, Wiley

    Dr Nicholas A Badcock, Dr. María Isabel Rodríguez-Franco

  32. Novel N -Acetyl Bioisosteres of Melatonin: Melatonergic Receptor Pharmacology, Physicochemical Studies, and Phenotypic Assessment of Their Neurogenic Potential

    Article • Journal of Medicinal Chemistry, June 2015, American Chemical Society (ACS)

    Dr Jose A Morales-Garcia, Dr. María Isabel Rodríguez-Franco

  33. Neurogenic Potential Assessment and Pharmacological Characterization of 6-Methoxy-1,2,3,4-tetrahydro-β-carboline (Pinoline) and Melatonin–Pinoline Hybrids

    Article • ACS Chemical Neuroscience, May 2015, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  34. The Melatonin– N , N -Dibenzyl( N -methyl)amine Hybrid ITH91/IQM157 Affords Neuroprotection in an in Vitro Alzheimer’s Model via Hemo-oxygenase-1 Induction

    Article • ACS Chemical Neuroscience, February 2015, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  35. Potent and selective MAO-B inhibitory activity: Amino- versus nitro-3-arylcoumarin derivatives

    Article • Bioorganic & Medicinal Chemistry Letters, February 2015, Elsevier

    Dr. María Isabel Rodríguez-Franco, Dr Maria João Matos, Dr Martin Estrada Valencia

  36. N -Methyl- N -((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1 H -indol-2-yl)methyl)prop-2-yn-1-amine, a New Cholinesterase and Monoamine Oxidase Dual Inhibitor

    Article • Journal of Medicinal Chemistry, December 2014, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  37. Novel Tacrine-Grafted Ugi Adducts as Multipotent Anti-Alzheimer Drugs: A Synthetic Renewal in Tacrine-Ferulic Acid Hybrids

    Article • ChemMedChem, December 2014, Wiley

    Dr. María Isabel Rodríguez-Franco

  38. ITH12410/SC058: A New Neuroprotective Compound with Potential in the Treatment of Alzheimer’s Disease

    Article • ACS Chemical Neuroscience, September 2014, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  39. Discovery of 5-(4-Hydroxyphenyl)-3-oxo-pentanoic Acid [2-(5-Methoxy-1H-indol-3-yl)-ethyl]-amide as a Neuroprotectant for Alzheimer’s Disease by Hybridization of Curcumin and Melatonin

    Article • ACS Chemical Neuroscience, August 2014, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco, Dr Martin Estrada Valencia

  40. Dibenzo[1,4,5]thiadiazepine: A hardly-known heterocyclic system with neuroprotective properties of potential usefulness in the treatment of neurodegenerative diseases

    Article • European Journal of Medicinal Chemistry, June 2014, Elsevier

    Dr. María Isabel Rodríguez-Franco

  41. New Melatonin– N , N -Dibenzyl( N -methyl)amine Hybrids: Potent Neurogenic Agents with Antioxidant, Cholinergic, and Neuroprotective Properties as Innovative Drugs for Alzheimer’s Disease

    Article • Journal of Medicinal Chemistry, May 2014, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  42. PP2A Ligand ITH12246 Protects against Memory Impairment and Focal Cerebral Ischemia in Mice

    Article • ACS Chemical Neuroscience, September 2013, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco, Dr Martin Estrada Valencia

  43. Multipotent, Permeable Drug ASS234 Inhibits Aβ Aggregation, Possesses Antioxidant Properties and Protects from Aβ-induced Apoptosis In Vitro

    Article • Current Alzheimer Research, September 2013, Bentham Science Publishers

    Dr. María Isabel Rodríguez-Franco, MERCEDES UNZETA

  44. Synthesis, pharmacological assessment, and molecular modeling of 6-chloro-pyridonepezils: New dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease

    Article • European Journal of Medicinal Chemistry, September 2013, Elsevier

    Dr. María Isabel Rodríguez-Franco

  45. Synthesis, Pharmacological Assessment, and Molecular Modeling of Acetylcholinesterase/Butyrylcholinesterase Inhibitors: Effect against Amyloid-β-Induced Neurotoxicity

    Article • ACS Chemical Neuroscience, April 2013, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  46. Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia

    Article • Neuropharmacology, April 2013, Elsevier

    Dr. María Isabel Rodríguez-Franco

  47. Pyridonepezils, new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease: Synthesis, biological assessment, and molecular modeling

    Article • European Journal of Medicinal Chemistry, November 2012, Elsevier

    Dr. María Isabel Rodríguez-Franco, Dr Martin Estrada Valencia

  48. Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9,10,11,12-tetrahydro-7H-benzo[7,8]chromeno[2,3-b]quinolin-8-amines as potential drugs for the treatment of Alzheimer's disease

    Article • European Journal of Medicinal Chemistry, August 2012, Elsevier

    Dr. María Isabel Rodríguez-Franco

  49. Benzothiazepine CGP37157 and Its Isosteric 2′-Methyl Analogue Provide Neuroprotection and Block Cell Calcium Entry

    Article • ACS Chemical Neuroscience, July 2012, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  50. Effects of a tacrine-8-hydroxyquinoline hybrid (IQM-622) on Aβ accumulation and cell death: Involvement in hippocampal neuronal loss in Alzheimer's disease

    Article • Neurobiology of Disease, June 2012, Elsevier

    Dr. María Isabel Rodríguez-Franco

  51. New Tacrine–4-Oxo-4 H -chromene Hybrids as Multifunctional Agents for the Treatment of Alzheimer’s Disease, with Cholinergic, Antioxidant, and β-Amyloid-Reducing Properties

    Article • Journal of Medicinal Chemistry, February 2012, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  52. Huprine–Tacrine Heterodimers as Anti-Amyloidogenic Compounds of Potential Interest against Alzheimer’s and Prion Diseases

    Article • Journal of Medicinal Chemistry, January 2012, American Chemical Society (ACS)

    Professor Cristina Minguillon, Dr. María Isabel Rodríguez-Franco

  53. α-Aryl- N -alkyl Nitrones, as Potential Agents for Stroke Treatment: Synthesis, Theoretical Calculations, Antioxidant, Anti-inflammatory, Neuroprotective, and Brain–Blood Barrier Permeability Properties

    Article • Journal of Medicinal Chemistry, January 2012, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  54. Multi-target novel neuroprotective compound ITH33/IQM9.21 inhibits calcium entry, calcium signals and exocytosis

    Article • Cell Calcium, October 2011, Elsevier

    Dr. María Isabel Rodríguez-Franco

  55. N-Acylaminophenothiazines: Neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer’s disease

    Article • European Journal of Medicinal Chemistry, June 2011, Elsevier

    Dr. María Isabel Rodríguez-Franco

  56. Alzheimer’s and Parkinson’s Diseases: Advances, Concepts and New Challenges

    Article • Neurodegenerative Diseases, January 2011, Karger Publishers

    Dr. María Isabel Rodríguez-Franco

  57. Old phenothiazine and dibenzothiadiazepine derivatives for tomorrow’s neuroprotective therapies against neurodegenerative diseases

    Article • European Journal of Medicinal Chemistry, December 2010, Elsevier

    Dr. María Isabel Rodríguez-Franco

  58. Novel Huprine Derivatives with Inhibitory Activity toward β-Amyloid Aggregation and Formation as Disease-Modifying Anti-Alzheimer Drug Candidates

    Article • ChemMedChem, September 2010, Wiley

    Dr. María Isabel Rodríguez-Franco

  59. Novel Tacrine−8-Hydroxyquinoline Hybrids as Multifunctional Agents for the Treatment of Alzheimer’s Disease, with Neuroprotective, Cholinergic, Antioxidant, and Copper-Complexing Properties

    Article • Journal of Medicinal Chemistry, July 2010, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  60. Neuroprotective and Cholinergic Properties of Multifunctional Glutamic Acid Derivatives for the Treatment of Alzheimer’s Disease

    Article • Journal of Medicinal Chemistry, November 2009, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  61. A New Tacrine–Melatonin Hybrid Reduces Amyloid Burden and Behavioral Deficits in a Mouse Model of Alzheimer’s Disease

    Article • Neurotoxicity Research, September 2009, Springer Science + Business Media

    Dr. María Isabel Rodríguez-Franco

  62. Pyrano[3,2- c ]quinoline−6-Chlorotacrine Hybrids as a Novel Family of Acetylcholinesterase- and β-Amyloid-Directed Anti-Alzheimer Compounds

    Article • Journal of Medicinal Chemistry, September 2009, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  63. Tacripyrines, the First Tacrine−Dihydropyridine Hybrids, as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease

    Article • Journal of Medicinal Chemistry, May 2009, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  64. Tacrine-Melatonin Hybrids as Multifunctional Agents for Alzheimer's Disease, with Cholinergic, Antioxidant, and Neuroprotective Properties

    Article • ChemMedChem, May 2009, Wiley

    Dr. María Isabel Rodríguez-Franco

  65. The Sodium Salt of Diethyl 1 H -pyrazole-3,5-dicarboxylate as an Efficient Amphiphilic Receptor for Dopamine and Amphetamines. Crystal Structure and Solution Studies

    Article • Journal of the American Chemical Society, December 2006, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  66. Antiobesity effects of the novel in vivo neutral cannabinoid receptor antagonist 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole – LH 21

    Article • Neuropharmacology, August 2006, Elsevier

    Dr. María Isabel Rodríguez-Franco, Dr. Nadine jagerovic

  67. Novel Tacrine−Melatonin Hybrids as Dual-Acting Drugs for Alzheimer Disease, with Improved Acetylcholinesterase Inhibitory and Antioxidant Properties

    Article • Journal of Medicinal Chemistry, January 2006, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  68. Design and synthesis of N-benzylpiperidine–purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase

    Article • Bioorganic & Medicinal Chemistry, December 2005, Elsevier

    Dr. María Isabel Rodríguez-Franco

  69. Synthesis and muscarinic activities of O-[(Benzyl- or benzoyl-pyrazolyl)propynyl]-oximes of N-methylpiperidinone, 3-tropinone, and 3-quinuclidinone

    Article • Bioorganic & Medicinal Chemistry, May 2003, Elsevier

    Dr. María Isabel Rodríguez-Franco

  70. Synthesis of New 1-(But-2-ynyl)pyrazoles: Containing a Pyrrolidine or Diethylamine Moiety and Their Muscarinic Properties

    Article • Archiv der Pharmazie, September 2002, Wiley

    Dr. María Isabel Rodríguez-Franco

  71. Complete assignment of the1H and13C NMR spectra of someN-benzyl-(piperidin or pyrrolidin)-purines

    Article • Magnetic Resonance in Chemistry, June 2002, Wiley

    Dr. María Isabel Rodríguez-Franco

  72. A mild and efficient method for the regioselective iodination of pyrazoles

    Article • Tetrahedron Letters, January 2001, Elsevier

    Dr. María Isabel Rodríguez-Franco

  73. N-Benzylpiperidine derivatives of 1,2,4-thiadiazolidinone as new acetylcholinesterase inhibitors

    Article • European Journal of Medicinal Chemistry, October 2000, Elsevier

    Dr. María Isabel Rodríguez-Franco

  74. Synthesis of NewN-(4-Pyridyl)-1-aminopyrazoles and Their Muscarinic and Adrenergic Properties

    Article • Archiv der Pharmazie, May 2000, Wiley

    Dr. María Isabel Rodríguez-Franco

  75. Hindered Inversion/Rotation in Diheteroaryl Alkyl Amines with a N-(1-Pyrazolyl) Group: Dynamic NMR and Molecular Modelling Studies

    Article • Tetrahedron, March 2000, Elsevier

    Dr. María Isabel Rodríguez-Franco

  76. Selective dopamine receptors: Synthesis, complexing properties, and molecular modelling studies of new podands derived from 4-hydroxy-1H-pyrazole

    Article • Tetrahedron, February 1999, Elsevier

    Dr. María Isabel Rodríguez-Franco

  77. Resolution of 1-(4-amino-3-chloro-5-cyanophenyl)-2-bromo-1-ethanol by lipase mediated enantioselective alcoholysis, hydrolysis and acylation

    Article • Tetrahedron Asymmetry, July 1998, Elsevier

    Dr. María Isabel Rodríguez-Franco

  78. Regioselective lipase catalyzed synthesis of diester crowns. New asymmetric macrocycles containing a 1,3-bis(1H-pyrazol-1-yl)propane unit

    Article • Tetrahedron, August 1997, Elsevier

    Dr. María Isabel Rodríguez-Franco

  79. Regioselective lipase-catalyzed synthesis of l-glutamic α-monoamide derivatives. Effect of the N-blocking group

    Article • Tetrahedron, August 1997, Elsevier

    Dr. María Isabel Rodríguez-Franco, Dr María Victoria Biezma Moraleda

  80. Intermediates in the synthesis of dipyrazolic podands and ester crowns via regioselective lipase catalyzed hydrolysis of a tetraester

    Article • Tetrahedron, February 1997, Elsevier

    Dr. María Isabel Rodríguez-Franco

  81. Selective carriers of norepinephrine and ammonium ions: Ionophoric properties and molecular modelling studies of diester crown compounds containing a 1,3-bis(1H-pyrazol-1-yl)propane unit

    Article • Bioorganic & Medicinal Chemistry, February 1997, Elsevier

    Dr. María Isabel Rodríguez-Franco

  82. Regioselective Mucor miehei lipase catalyzed synthesis of podands containing a 1,3-bis(1H-Pyrazol-1-yl)propane unit

    Article • Tetrahedron, February 1995, Elsevier

    Dr. María Isabel Rodríguez-Franco

  83. First regioselective mucor miehei lipase catalyzed synthesis of diester crowns. New macrocycles containing a 1,3-bis(1H-pyrazol-1-yl)propane unit

    Article • Bioorganic & Medicinal Chemistry Letters, November 1994, Elsevier

    Dr. María Isabel Rodríguez-Franco

  84. Formation of mono- and di- nuclear complexes of Zn2+ from a 26 membered tetraester crown of 3,5-disubstituted pyrazole able to act as neutral and dianionic ligand

    Article • Tetrahedron, April 1994, Elsevier

    Dr. María Isabel Rodríguez-Franco

  85. Mucor miehei lipase catalyzed transesterifications on aromatic and heteroaromatic substrates. A general survey

    Article • Tetrahedron, January 1994, Elsevier

    Dr. María Isabel Rodríguez-Franco

  86. Synthesis and ionophoric properties of a new series of polyester heterocyclophanes of 3,5-disubstituted 1-methylpyrazole and 2,6-bis(methylene)pyridine

    Article • Tetrahedron, January 1990, Elsevier

    Dr. María Isabel Rodríguez-Franco

  87. Selective carriers of ammonium ions. I. Synthesis and template effect of cesium chloride and x-ray structure and ionophoric properties of polyether crowns containing 1-methyl-3,5-bis(methylene)-1H-pyrazole units

    Article • The Journal of Organic Chemistry, March 1989, American Chemical Society (ACS)

    Dr. María Isabel Rodríguez-Franco

  88. Efficient transport of alkali and ammonium ions by proton-ionizable ester crowns containing 1H-pyrazole units. Symmetric complexing behaviour towards europium observed by13C n.m.r. spectroscopy

    Article • Journal of the Chemical Society Chemical Communications, January 1988, Royal Society of Chemistry

    Dr. María Isabel Rodríguez-Franco

  89. Synthesis, cytostatic and trichomonacide activities of 3,5-bis-(halomethyl)pyrazoles

    Article • European Journal of Medicinal Chemistry, September 1987, Elsevier

    Dr. María Isabel Rodríguez-Franco

  90. Caesium-Assisted Cyclization of Large Polyether Hexa- and Octaester Pyrazolic Crowns

    Article • Synthetic Communications, January 1987, Taylor & Francis

    Dr. María Isabel Rodríguez-Franco

  91. SYNTHESIS OF NEW MACROCYCLIC POLYETHER DI- OR TETRAESTER LIGANDS CONTAINING PYRAZOLE UNITS

    Article • Chemistry Letters, March 1984, The Chemical Society of Japan

    Dr. María Isabel Rodríguez-Franco