All Stories

  1. Identification of L. infantum trypanothione synthetase inhibitors with leishmanicidal activity from a (non-biased) in-house chemical library
  2. Antinociceptive and modulatory effect of pathoplastic changes in spinal glia of a TLR4/CD14 blocking molecule in two models of pain in rat
  3. Pradimicin and Benanomicin Antibiotics: From Antifungal Polyketide Natural Products to Antiviral Agents with a Unique Carbohydrate- Binding Mode of Action
  4. TLR4 Antagonism Reduces Movement-Induced Nociception and ATF-3 Expression in Experimental Osteoarthritis
  5. Double Arylation of the Indole Side Chain of Tri- and Tetrapodal Tryptophan Derivatives Renders Highly Potent HIV-1 and EV-A71 Entry Inhibitors
  6. A SCAFFOLD SIMPLIFICATION STRATEGY LEADS TO A NOVEL GENERATION OF DUAL HUMAN IMMUNODEFICIENCY VIRUS AND ENTEROVIRUS-A71 ENTRY INHIBITORS
  7. Conformational mimetics of the α-methyl chalcone TUB091 binding tubulin: Design, synthesis and antiproliferative activity
  8. SAT0494 Early toll-like receptor 4 blockade impedes the behavioural and histological characteristics observed in a mia-induced animal model of osteoarthritic pain
  9. AB0043 TLR4 inhibition reduces movement-induced nociception and ATF-3 expression in experimental osteoarthritis
  10. Structure-activity relationship studies on a Trp dendrimer with dual activities against HIV and enterovirus A71. Modifications on the amino acid
  11. Optimization of a Class of Tryptophan Dendrimers That Inhibit HIV Replication Leads to a Selective, Specific, and Low-Nanomolar Inhibitor of Clinical Isolates of Enterovirus A71
  12. Anti-HIV-1 activity of a tripodal receptor that recognizes mannose oligomers
  13. Tryptophan dendrimers that inhibit HIV replication, prevent virus entry and bind to the HIV envelope glycoproteins gp120 and gp41
  14. Linear and branched alkyl-esters and amides of gallic acid and other (mono-, di- and tri-) hydroxy benzoyl derivatives as promising anti-HCV inhibitors
  15. Multivalent agents containing 1-substituted 2,3,4-trihydroxyphenyl moieties as novel synthetic polyphenols directed against HIV-1
  16. Entry Inhibitors Directed Towards Glycoprotein gp120: An Overview on a Promising Target for HIV-1 Therapy
  17. Differential Recognition of Mannose-Based Polysaccharides by Tripodal Receptors Based on a Triethylbenzene Scaffold Substituted with Trihydroxybenzoyl Moieties
  18. Selective inhibition of Human Immunodeficiency Virus type 1 (HIV-1) by a novel family of tricyclic nucleosides
  19. One-Pot Synthesis of Polycyclic Nucleosides with Unusual Molecular Skeletons
  20. Novel N-3 Substituted TSAO-T Derivatives: Synthesis and Anti-HIV-Evaluation
  21. Synthesis of Highly Condensed Polycyclic Carbohydrates by Reaction of a Spirocyclic Enamino Sulfonate Derived fromd-Xylofuranose with Bifunctional Reagents
  22. Synthesis and Spectral Properties of Amphiphilic Lipids with Linear Conjugated Polyene and Phenylpolyene Fluorescent Groups
  23. A Cyclic Enamine Derived from 1,2-O-Isopropylidene-α-d-xylofuranose As a Novel Carbohydrate Intermediate To Achieve Skeletal Diversity
  24. One-pot conversion of activated alcohols into 1,1-dibromoalkenes and terminal alkynes using tandem oxidation processes with manganese dioxide
  25. Dynamics of bolaamphiphilic fluorescent polyenes in lipid bilayers from polarization emission spectroscopy
  26. One-pot conversion of activated alcohols into terminal alkynes using manganese dioxide in combination with the Bestmann–Ohira reagent
  27. Tandem Horner-Wadsworth-Emmons Olefination/Claisen Rearrangement/Hydrolysis Sequence: Remarkable Acceleration in Water with Microwave Irradiation
  28. Fluorescent Phenylpolyene Analogues of the Ether Phospholipid Edelfosine for the Selective Labeling of Cancer Cells
  29. The first total syntheses of (±)-Preussomerins K and L using 2-arylacetal anion technology
  30. A versatile, non-biomimetic route to the preussomerins: syntheses of (±)-preussomerins F, K and L
  31. Leads for Development of New Naphthalenesulfonate Derivatives with Enhanced Antiangiogenic Activity: CRYSTAL STRUCTURE OF ACIDIC FIBROBLAST GROWTH FACTOR IN COMPLEX WITH 5-AMINO-2-NAPHTHALENESULFONATE
  32. Synthesis of Carboxyl-Tethered Symmetric Conjugated Polyenes as Fluorescent Transmembrane Probes of Lipid Bilayers
  33. New Transmembrane Polyene Bolaamphiphiles as Fluorescent Probes in Lipid Bilayers
  34. New Transmembrane Polyene Bolaamphiphiles as Fluorescent Probes in Lipid Bilayers
  35. Synthesis and Fluorescence Properties of Novel Transmembrane Probes and Determination of Their Orientation within Vesicles
  36. Synthesis of Crowned Triazolephthalocyanines