All Stories

  1. The Role of Hydrogen Bond Donors and Intramolecular Hydrogen Bonding in Modulating Blood–Brain Barrier Permeability: Implications for CNS Drug Design

    Article • Molecules, July 2026, MDPI AG

    Dr Maria João Matos

  2. Design, Synthesis, and Evaluation of Coumarin‐Rasagiline Hybrids as Multifunctional Neuroprotective Agents

    Article • ChemMedChem, May 2026, Wiley

    Dr Maria João Matos

  3. Exploring 6‐Hydroxy‐3‐Aryl/Heteroarylcoumarins as Promising Candidates Against Trypanosoma cruzi

    Article • ChemMedChem, April 2026, Wiley

    Dr Maria João Matos

  4. The futility of the familiar: rethinking strategies for the development of small molecules for neurodegenerative disorders

    Article • Expert Opinion on Drug Discovery, March 2026, Taylor & Francis

    Dr Maria João Matos

  5. 2-Arylbenzofurans as Selective Cholinesterase Inhibitors: Design, Synthesis, and Evaluation as Alzheimer’s Disease Agents

    Article • Biomolecules, January 2026, MDPI AG

    Dr Maria João Matos

  6. Biosafety Evaluation of 6,7‐Dihydroxy‐3‐(2‐Nitrophenyl)Coumarin in Human Cells

    Article • Journal of Applied Toxicology, August 2025, Wiley

    Dr Maria João Matos

  7. The Role of Trifluoromethyl and Trifluoromethoxy Groups in Medicinal Chemistry: Implications for Drug Design

    Article • Molecules, July 2025, MDPI AG

    Dr Maria João Matos

  8. Exploring Trisubstituted adenine derivatives as adenosine A1 receptor ligands with antagonist activity: Synthesis, biological evaluation and molecular modelling

    Article • Bioorganic Chemistry, June 2025, Elsevier

    Dr Maria João Matos, Dr Juan J Diaz-Mochon

  9. A New Class of Benzo[b]thiophene-chalcones as Cholinesterase Inhibitors: Synthesis, Biological Evaluation, Molecular Docking and ADME Studies

    Article • Molecules, August 2024, MDPI AG

    Dr Maria João Matos

  10. Seaweeds as Source of Bioactive Pigments with Neuroprotective and/or Anti-Neurodegenerative Activities: Astaxanthin and Fucoxanthin

    Article • Marine Drugs, July 2024, MDPI AG

    Dr Maria João Matos

  11. Empowering Voices: Inspiring Women in Medicinal Chemistry

    Article • ACS Medicinal Chemistry Letters, March 2024, American Chemical Society (ACS)

    Dr Maria João Matos

  12. Empowering Voices: Inspiring Women in Medicinal Chemistry

    Article • Journal of Medicinal Chemistry, March 2024, American Chemical Society (ACS)

    Dr Maria João Matos

  13. N-(coumarin-3-yl)cinnamamide Promotes Immunomodulatory, Neuroprotective, and Lung Function-Preserving Effects during Severe Malaria

    Article • Pharmaceuticals, December 2023, MDPI AG

    Dr Maria João Matos

  14. Front Cover: Design of 3‐Phenylcoumarins and 3‐Thienylcoumarins as Potent Xanthine Oxidase Inhibitors: Synthesis, Biological Evaluation, and Docking Studies (ChemMedChem 21/2023)

    Article • ChemMedChem, November 2023, Wiley

    Dr Maria João Matos

  15. Study of the DNA damage and cell death in human peripheral blood mononuclear and HepG2/C3A cells exposed to the synthetic 3-(3-hydroxyphenyl)-7-hydroxycoumarin

    Article • Journal of Toxicology and Environmental Health Part A, October 2023, Taylor & Francis

    Dr Maria João Matos

  16. Design of 3‐Phenylcoumarins and 3‐Thienylcoumarins as Potent Xanthine Oxidase Inhibitors: Synthesis, Biological Evaluation, and Docking Studies

    Article • ChemMedChem, October 2023, Wiley

    Dr Maria João Matos

  17. Evaluation of in vitro cytotoxic and genotoxic effects of the 3‐(3,4‐dihydroxyphenyl)‐8‐hydroxycoumarin

    Article • Journal of Applied Toxicology, May 2023, Wiley

    Dr Maria João Matos

  18. Oxidation-labile linkers for controlled drug delivery

    Article • Bioorganic & Medicinal Chemistry Letters, May 2023, Elsevier

    Dr Maria João Matos

  19. 8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies

    Article • European Journal of Medicinal Chemistry, February 2023, Elsevier

    Dr. María Isabel Rodríguez-Franco, Dr Maria João Matos

  20. In silico approaches to develop new phenyl-pyrimidines as glycogen synthase kinase 3 (GSK-3) inhibitors with halogen-bonding capabilities: 3D-QSAR CoMFA/CoMSIA, molecular docking and molecular dynamics studies

    Article • Journal of Biomolecular Structure and Dynamics, January 2023, Taylor & Francis

    Dr Maria João Matos

  21. Propargylamine: an Important Moiety in Drug Discovery

    Article • Future Medicinal Chemistry, January 2023, Taylor & Francis

    Dr Maria João Matos

  22. Recent Advances in Biologically Active Coumarins from Marine Sources: Synthesis and Evaluation

    Article • Marine Drugs, December 2022, MDPI AG

    Dr Maria João Matos

  23. Front Cover: Synthesis and Vasorelaxant Activity of Nitrate−Coumarin Derivatives (ChemMedChem 21/2022)

    Article • ChemMedChem, November 2022, Wiley

    Dr Maria João Matos

  24. Hydroxy-3-Phenylcoumarins as Multitarget Compounds for Skin Aging Diseases: Synthesis, Molecular Docking and Tyrosinase, Elastase, Collagenase and Hyaluronidase Inhibition, and Sun Protection Factor

    Article • Molecules, October 2022, MDPI AG

    Dr Maria João Matos

  25. Synthesis and Vasorelaxant Activity of Nitrate−Coumarin Derivatives

    Article • ChemMedChem, October 2022, Wiley

    Dr Maria João Matos

  26. Cytogenotoxicity assessment of 3‐(3,4‐dihydroxyphenyl)‐7,8‐dihydroxycoumarin on HepG2/C3A cells and leukocytes

    Article • Journal of Applied Toxicology, September 2022, Wiley

    Dr Maria João Matos

  27. Thiocoumarins: From the Synthesis to the Biological Applications

    Article • Molecules, July 2022, MDPI AG

    Dr Maria João Matos

  28. Medicinal Chemistry in Portugal and Spain: A Strong Iberian Alliance

    Article • ACS Medicinal Chemistry Letters, June 2022, American Chemical Society (ACS)

    Dr Maria João Matos

  29. Treating Neurodegenerative Diseases with Multitarget Drugs: An Interview With Maria João Matos

    Article • Future Medicinal Chemistry, May 2022, Taylor & Francis

    Dr Maria João Matos

  30. A comprehensive ethnobotanical profile ofOcimum campechianum(Lamiaceae): from traditional medicine to phytochemical and pharmacological evidences

    Article • Plant Biosystems, April 2022, Taylor & Francis

    Dr Maria João Matos

  31. Single Mutation on Trastuzumab Modulates the Stability of Antibody–Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry

    Article • Journal of the American Chemical Society, March 2022, American Chemical Society (ACS)

    Dr Maria João Matos

  32. Structural Insight of New Butyrylcholinesterase Inhibitors Based on Benzylbenzofuran Scaffold

    Article • Pharmaceuticals, March 2022, MDPI AG

    Dr Maria João Matos

  33. Synthesis and study of the trypanocidal activity of catechol-containing 3-arylcoumarins, inclusion in β-cyclodextrin complexes and combination with benznidazole

    Article • Arabian Journal of Chemistry, March 2022, Scientific Scholar

    Dr Maria João Matos

  34. Coumarin-Resveratrol-Inspired Hybrids as Monoamine Oxidase B Inhibitors: 3-Phenylcoumarin versus trans-6-Styrylcoumarin

    Article • Molecules, January 2022, MDPI AG

    Dr Maria João Matos

  35. 8-Amide and 8-Carbamate Substitution Patterns as Modulators of 7-Hydroxy-4-Methylcoumarin's Antidepressant Profile: Synthesis, MAO Inhibition, Cytotoxicity and Docking Studies

    Article • SSRN Electronic Journal, January 2022, Elsevier

    Dr Maria João Matos

  36. 3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade

    Article • Molecules, November 2021, MDPI AG

    Dr Maria João Matos

  37. Coumarin and Its Derivatives—Editorial

    Article • Molecules, October 2021, MDPI AG

    Dr Maria João Matos

  38. Study of a Selected Series of 3‐ and 4‐Arylcoumarins as Antifungal Agents against Dermatophytic Fungi: T. rubrum and T. mentagrophytes

    Article • ChemistrySelect, October 2021, Wiley

    Dr Maria João Matos

  39. Computer-aided Design of Coumarins for Neurodegenerative Diseases: Trends of the Last Decade

    Article • Current Topics in Medicinal Chemistry, October 2021, Bentham Science Publishers

    Professor Fernanda Borges, Dr Maria João Matos, Eugenio Uriarte

  40. Theobroma cacao L. compounds: Theoretical study and molecular modeling as inhibitors of main SARS-CoV-2 protease

    Article • Biomedicine & Pharmacotherapy, August 2021, Elsevier

    Angelica Sandoval Aldana, Dr Maria João Matos

  41. Multitarget Therapeutic Approaches for Alzheimer's and Parkinson's Diseases: An Opportunity or an illusion?

    Article • Future Medicinal Chemistry, June 2021, Taylor & Francis

    Dr Maria João Matos

  42. Medicinal Chemistry in Portugal and Spain: A Strong Iberian Alliance — Call for Papers

    Article • ACS Medicinal Chemistry Letters, April 2021, American Chemical Society (ACS)

    Dr Maria João Matos

  43. Chemical and biological analysis of 4-acyloxy-3-nitrocoumarins as trypanocidal agents

    Article • Arabian Journal of Chemistry, March 2021, Scientific Scholar

    Dr Maria João Matos

  44. Combined 3D-QSAR and docking analysis for the design and synthesis of chalcones as potent and selective monoamine oxidase B inhibitors

    Article • Bioorganic Chemistry, March 2021, Elsevier

    Dr Maria João Matos

  45. Study of 3-(4’-Nitrobenzamido)coumarin using an Alzheimer’s Disease Model

    Article • February 2021, Springer Science + Business Media

    Dr Maria João Matos

  46. Trending Topics on Coumarin and Its Derivatives in 2020

    Article • Molecules, January 2021, MDPI AG

    Dr Maria João Matos

  47. Sequential dual site-selective protein labelling enabled by lysine modification

    Article • Bioorganic & Medicinal Chemistry, November 2020, Elsevier

    Dr Maria João Matos

  48. Looking for new xanthine oxidase inhibitors: 3-Phenylcoumarins versus 2-phenylbenzofurans

    Article • International Journal of Biological Macromolecules, November 2020, Elsevier

    Dr Maria João Matos

  49. Adenosine Receptor Ligands: Coumarin–Chalcone Hybrids as Modulating Agents on the Activity of hARs

    Article • Molecules, September 2020, MDPI AG

    Dr Maria João Matos

  50. 7‐Amidocoumarins as Multitarget Agents against Neurodegenerative Diseases: Substitution Pattern Modulation

    Article • ChemMedChem, August 2020, Wiley

    Dr Maria João Matos

  51. Discovery and optimization of 3-thiophenylcoumarins as novel agents against Parkinson’s disease: Synthesis, in vitro and in vivo studies

    Article • Bioorganic Chemistry, August 2020, Elsevier

    Dr Maria João Matos

  52. 3-Arylcoumarins as highly potent and selective monoamine oxidase B inhibitors: Which chemical features matter?

    Article • Bioorganic Chemistry, August 2020, Elsevier

    Dr Maria João Matos

  53. Coumarin‐Rasagiline Hybrids as Potent and Selective hMAO‐B Inhibitors, Antioxidants, and Neuroprotective Agents

    Article • ChemMedChem, February 2020, Wiley

    Dr Maria João Matos

  54. Structure-Based Optimization of Coumarin hA3 Adenosine Receptor Antagonists

    Article • Journal of Medicinal Chemistry, December 2019, American Chemical Society (ACS)

    Dr Maria João Matos, Professor Fernanda Borges

  55. Artificial Intelligence Applied to Flavonoid Data in Food Matrices

    Article • Foods, November 2019, MDPI AG

    Dr Maria João Matos

  56. Facing Novel Challenges in Neurodegenerative Diseases Drug Discovery: From Small Molecules to Targeted Therapies

    Article • August 2019, MDPI AG

    Dr Maria João Matos

  57. Antibacterial Activity and Molecular Docking Studies of a Selected Series of Hydroxy-3-arylcoumarins

    Article • Molecules, August 2019, MDPI AG

    Dr Maria João Matos

  58. Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification

    Article • ACS Central Science, July 2019, American Chemical Society (ACS)

    Dr Maria João Matos

  59. Design, Synthesis and Docking Calculations of Prenylated Chalcones as Selective Monoamine Oxidase B Inhibitors with Antioxidant Activity

    Article • ChemistrySelect, July 2019, Wiley

    Dr Maria João Matos

  60. Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine‐Selective Protein Modification and Charge Modulation

    Article • Angewandte Chemie, April 2019, Wiley

    Dr Maria João Matos

  61. Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine‐Selective Protein Modification and Charge Modulation

    Article • Angewandte Chemie, April 2019, Wiley

    Dr Maria João Matos

  62. Synthesis, molecular docking and cholinesterase inhibitory activity of hydroxylated 2-phenylbenzofuran derivatives

    Article • Bioorganic Chemistry, March 2019, Elsevier

    Dr Maria João Matos

  63. Targeting α -(1,4)-Glucosidase in Diabetes Mellitus Type 2: The Role of New Synthetic Coumarins as Potent Inhibitors

    Article • Current Topics in Medicinal Chemistry, January 2019, Bentham Science Publishers

    Dr Maria João Matos, Eugenio Uriarte, Catalina Figueroa, Rubén Veas

  64. Novel Coumarin-Quinoline Hybrids: Design of Multitarget Compounds for Alzheimer's Disease

    Article • ChemistrySelect, January 2019, Wiley

    Dr Maria João Matos, Dr Jans H. Alzate-Morales

  65. Lysine Bioconjugation on Native Albumin with a Sulfonyl Acrylate Reagent

    Article • January 2019, Springer Science + Business Media

    Dr Maria João Matos

  66. Coumarin derivatives as promising xanthine oxidase inhibitors

    Article • International Journal of Biological Macromolecules, December 2018, Elsevier

    Dr Maria João Matos

  67. Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents

    Article • Nature Protocols, November 2018, Springer Science + Business Media

    Dr Maria João Matos

  68. PEGylated PLGA Nanoparticles As a Smart Carrier to Increase the Cellular Uptake of a Coumarin-Based Monoamine Oxidase B Inhibitor

    Article • ACS Applied Materials & Interfaces, October 2018, American Chemical Society (ACS)

    Dr Maria João Matos, Professor Fernanda Borges

  69. Synthesis and Biological Evaluation of Homogeneous Thiol-Linked NHC*-Au-Albumin and -Trastuzumab Bioconjugates

    Article • Chemistry - A European Journal, May 2018, Wiley

    Dr Maria João Matos

  70. Unexpected one-step synthesis of 3-benzoyl-2-phenylbenzofurans under Wittig conditions

    Article • Tetrahedron Letters, May 2018, Elsevier

    Dr Maria João Matos

  71. A silicon-labelled amino acid suitable for late-stage fluorination and unexpected oxidative cleavage reactions in the preparation of a key intermediate in the Strecker synthesis

    Article • Peptide Science, April 2018, Wiley

    Dr Maria João Matos

  72. Evaluation of trypanocidal and antioxidant activities of a selected series of 3-amidocoumarins

    Article • Medicinal Chemistry, April 2018, Bentham Science Publishers

    Dr Maria João Matos, Eugenio Uriarte, Michel Lapier

  73. Learning from nature: the role of albumin in drug delivery

    Article • Future Medicinal Chemistry, April 2018, Future Science

    Dr Maria João Matos

  74. Trends in patented chromones for skin diseases

    Article • Pharmaceutical Patent Analyst, April 2018, Future Science

    Dr Maria João Matos

  75. Novel 2-pheynlbenzofuran derivatives as selective butyrylcholinesterase inhibitors for Alzheimer’s disease

    Article • Scientific Reports, March 2018, Springer Science + Business Media

    Dr Maria João Matos

  76. Chemo- and Regioselective Lysine Modification on Native Proteins

    Article • Journal of the American Chemical Society, February 2018, American Chemical Society (ACS)

    Dr Maria João Matos

  77. Coumarins as Promising Scaffold for the Treatment of Age-related Diseases – An Overview of the Last Five Years

    Article • Current Topics in Medicinal Chemistry, January 2018, Bentham Science Publishers

    Dr Maria João Matos

  78. A thioether-directed palladium-cleavable linker for targeted bioorthogonal drug decaging

    Article • Chemical Science, January 2018, Royal Society of Chemistry

    Dr Maria João Matos

  79. Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation

    Article • Journal of the American Chemical Society, December 2017, American Chemical Society (ACS)

    Dr Maria João Matos

  80. Coumarins and adenosine receptors: New perceptions in structure-affinity relationships

    Article • Chemical Biology & Drug Design, September 2017, Wiley

    Dr Maria João Matos, Professor Fernanda Borges

  81. Coumarin versus Chromone Monoamine Oxidase B Inhibitors: Quo Vadis?

    Article • Journal of Medicinal Chemistry, August 2017, American Chemical Society (ACS)

    Dr Maria João Matos, Professor Fernanda Borges

  82. New insights into highly potent tyrosinase inhibitors based on 3-heteroarylcoumarins: Anti-melanogenesis and antioxidant activities, and computational molecular modeling studies

    Article • Bioorganic & Medicinal Chemistry, March 2017, Elsevier

    Dr Maria João Matos, Professor Fernanda Borges

  83. Heterocyclic Antioxidants in Nature: Coumarins

    Article • Current Organic Chemistry, January 2017, Bentham Science Publishers

    Dr Maria João Matos, Professor Fernanda Borges

  84. Synthesis, antioxidant and antichagasic properties of a selected series of hydroxy-3-arylcoumarins

    Article • Bioorganic & Medicinal Chemistry, January 2017, Elsevier

    Dr Maria João Matos

  85. In silico genotoxicity of coumarins: application of the Phenol-Explorer food database to functional food science

    Article • Food & Function, January 2017, Royal Society of Chemistry

    Dr Maria João Matos

  86. MAO inhibitory activity of bromo-2-phenylbenzofurans: synthesis, in vitro study, and docking calculations

    Article • MedChemComm, January 2017, Royal Society of Chemistry

    Dr Maria João Matos, Professor Fernanda Borges

  87. Trends in therapeutic drug conjugates for bacterial diseases: a patent review

    Article • Expert Opinion on Therapeutic Patents, November 2016, Taylor & Francis

    Dr Maria João Matos

  88. Structural elucidation of a series of 6-methyl-3-carboxamidocoumarins

    Article • Magnetic Resonance in Chemistry, November 2016, Wiley

    Dr Maria João Matos, Professor Fernanda Borges

  89. In silico study of new structural alerts of agents clastogenic

    Article • November 2016, MDPI AG

    Dr Maria João Matos

  90. Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents

    Article • Nature Communications, October 2016, Springer Science + Business Media

    Dr Maria João Matos

  91. Evaluation of Antioxidant and Antitrypanosomal Properties of a Selected Series of Synthetic 3-Carboxamidocoumarins

    Article • ChemistrySelect, September 2016, Wiley

    Dr Maria João Matos, Professor Fernanda Borges

  92. Facing Chagas' Disease: Trypanocidal Properties of New Coumarinchalcone Scaffolds

    Article • Medicinal Chemistry, July 2016, Bentham Science Publishers

    Dr Maria João Matos

  93. 6-Methyl-2-oxo-N-(quinolin-6-yl)-2H-chromene-3-carboxamide: crystal structure and Hirshfeld surface analysis

    Article • Acta Crystallographica Section E Crystallographic Communications, July 2016, International Union of Crystallography

    Dr John N Low, Dr Maria João Matos, Professor Fernanda Borges

  94. Crystal structures of three 6-substituted coumarin-3-carboxamide derivatives

    Article • Acta Crystallographica Section E Crystallographic Communications, June 2016, International Union of Crystallography

    Dr John N Low, Dr Maria João Matos, Professor Fernanda Borges

  95. 2-Phenylbenzofuran derivatives as butyrylcholinesterase inhibitors: Synthesis, biological activity and molecular modeling

    Article • Bioorganic & Medicinal Chemistry Letters, May 2016, Elsevier

    Dr Maria João Matos

  96. Exploring coumarin potentialities: development of new enzymatic inhibitors based on the 6-methyl-3-carboxamidocoumarin scaffold

    Article • RSC Advances, January 2016, Royal Society of Chemistry

    Dr Maria João Matos, Professor Fernanda Borges

  97. Progress in the development of small molecules as new human A3 adenosine receptor ligands based on the 3-thiophenylcoumarin core

    Article • MedChemComm, January 2016, Royal Society of Chemistry

    Dr Maria João Matos, Professor Fernanda Borges

  98. Prediction of the total antioxidant capacity of food based on artificial intelligence algorithms

    Article • December 2015, MDPI AG

    Dr Maria João Matos

  99. Design, synthesis and antibacterial study of new potent and selective coumarin–chalcone derivatives for the treatment of tenacibaculosis

    Article • Bioorganic & Medicinal Chemistry, November 2015, Elsevier

    Dr Maria João Matos, Professor Fernanda Borges

  100. 3-Amidocoumarins as Potential Multifunctional Agents against Neurodegenerative Diseases

    Article • ChemMedChem, October 2015, Wiley

    Dr. María Isabel Rodríguez-Franco, Dr Maria João Matos, Dr Martin Estrada Valencia, Professor Fernanda Borges

  101. Coumarins — An Important Class of Phytochemicals

    Article • September 2015, IntechOpen

    Dr Maria João Matos

  102. Development of novel adenosine receptor ligands based on the 3-amidocoumarin scaffold

    Article • Bioorganic Chemistry, August 2015, Elsevier

    Dr Maria João Matos, Professor Fernanda Borges

  103. Bioactive Coumarins from Marine Sources: Origin, Structural Features and Pharmacological Properties

    Article • Current Topics in Medicinal Chemistry, June 2015, Bentham Science Publishers

    Dr Maria João Matos, Professor Fernanda Borges

  104. In silico clastogenic activity of dietary phenolic acids

    Article • LWT, April 2015, Elsevier

    Dr Maria João Matos

  105. Interest of Antioxidant Agents in Parasitic Diseases. The Case Study of Coumarins

    Article • Current Topics in Medicinal Chemistry, March 2015, Bentham Science Publishers

    Professor Fernanda Borges, Dr Maria João Matos

  106. Oxidative Stress and Neurodegenerative Diseases: Looking for a Therapeutic Solution Inspired on Benzopyran Chemistry

    Article • Current Topics in Medicinal Chemistry, February 2015, Bentham Science Publishers

    Professor Fernanda Borges, Dr Maria João Matos

  107. Study of Coumarin-Resveratrol Hybrids as Potent Antioxidant Compounds

    Article • Molecules, February 2015, MDPI AG

    Professor Fernanda Borges, Dr Maria João Matos

  108. Potent and selective MAO-B inhibitory activity: Amino- versus nitro-3-arylcoumarin derivatives

    Article • Bioorganic & Medicinal Chemistry Letters, February 2015, Elsevier

    Dr. María Isabel Rodríguez-Franco, Dr Maria João Matos, Dr Martin Estrada Valencia

  109. Potential pharmacological uses of chalcones: a patent review (from June 2011 – 2014)

    Article • Expert Opinion on Therapeutic Patents, January 2015, Informa Healthcare

    Dr Maria João Matos

  110. Design and discovery of tyrosinase inhibitors based on a coumarin scaffold

    Article • RSC Advances, January 2015, Royal Society of Chemistry

    Dr Maria João Matos, Professor Fernanda Borges

  111. Back Cover: Insight into the Interactions between Novel Coumarin Derivatives and Human A3 Adenosine Receptors (ChemMedChem 10/2014)

    Article • ChemMedChem, September 2014, Wiley

    Dr Maria João Matos, Professor Fernanda Borges

  112. Insight into the Interactions between Novel Coumarin Derivatives and Human A3 Adenosine Receptors

    Article • ChemMedChem, July 2014, Wiley

    Dr Maria João Matos, Professor Fernanda Borges

  113. Synthesis and electrochemical study of new 3-(hydroxyphenyl)benzo[f]coumarins

    Article • Journal of Electroanalytical Chemistry, July 2014, Elsevier

    Dr Maria João Matos

  114. Insight into the Functional and Structural Properties of 3‐Arylcoumarin as an Interesting Scaffold in Monoamine Oxidase B Inhibition

    Article • ChemMedChem, April 2014, Wiley

    Dr Maria João Matos

  115. Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases

    Article • Future Medicinal Chemistry, March 2014, Future Science

    Dr Maria João Matos, Professor Fernanda Borges

  116. Chromone: A Valid Scaffold in Medicinal Chemistry

    Article • Chemical Reviews, February 2014, American Chemical Society (ACS)

    Dr Maria João Matos, Professor Fernanda Borges

  117. Synthesis and evaluation of antioxidant and trypanocidal properties of a selected series of coumarin derivatives

    Article • Future Medicinal Chemistry, October 2013, Future Science

    Dr Maria João Matos

  118. Comparative study of the 3-phenylcoumarin scaffold: Synthesis, X-ray structural analysis and semiempirical calculations of a selected series of compounds

    Article • Journal of Molecular Structure, October 2013, Elsevier

    Dr Maria João Matos

  119. Synthesis and adenosine receptors binding affinities of a series of 3-arylcoumarins

    Article • Journal of Pharmacy and Pharmacology, August 2013, Oxford University Press (OUP)

    Dr Maria João Matos, Professor Fernanda Borges

  120. QSAR and Complex Network Recognition of miRNAs in Stem Cells

    Article • Current Bioinformatics, August 2013, Bentham Science Publishers

    Professor Fernanda Borges, Dr Maria João Matos

  121. Synthesis and Electrochemical and Biological Studies of Novel Coumarin–Chalcone Hybrid Compounds

    Article • Journal of Medicinal Chemistry, July 2013, American Chemical Society (ACS)

    Dr Maria João Matos

  122. Remarkable antioxidant properties of a series of hydroxy-3-arylcoumarins

    Article • Bioorganic & Medicinal Chemistry, July 2013, Elsevier

    Dr Maria João Matos, Professor Fernanda Borges

  123. Synthesis, NMR characterization, X-ray structural analysis and theoretical calculations of amide and ester derivatives of the coumarin scaffold

    Article • Journal of Molecular Structure, June 2013, Elsevier

    Dr Maria João Matos

  124. Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: Synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study

    Article • European Journal of Medicinal Chemistry, May 2013, Elsevier

    Dr Maria João Matos

  125. (1S,2S,5S)-2-Methyl-3-oxo-5-(prop-1-en-2-yl)cyclohexane-1-carbonitrile

    Article • Acta Crystallographica Section E Structure Reports Online, April 2013, International Union of Crystallography

    Dr Maria João Matos

  126. [(2S,3aR,6aR)-5-Oxohexahydrofuro[3,2-b]furan-2-yl]methyl acetate

    Article • Acta Crystallographica Section E Structure Reports Online, April 2013, International Union of Crystallography

    Dr Maria João Matos

  127. MAO Inhibitory Activity of 2‐Arylbenzofurans versus 3‐Arylcoumarins: Synthesis, in vitro Study, and Docking Calculations

    Article • ChemMedChem, April 2013, Wiley

    Dr Maria João Matos

  128. ChemInform Abstract: Improved Synthesis of 3‐(Aminoaryl)coumarins.

    Article • ChemInform, March 2013, Wiley

    Dr Maria João Matos, Professor Fernanda Borges

  129. Editorial (Hot Topic: Monoamine Oxidase as a Target in Medicinal Chemistry and Drug Discovery)

    Article • Current Topics in Medicinal Chemistry, February 2013, Bentham Science Publishers

    Dr Maria João Matos

  130. Focusing on New Monoamine Oxidase Inhibitors: Differently Substituted Coumarins As An Interesting Scaffold

    Article • Current Topics in Medicinal Chemistry, February 2013, Bentham Science Publishers

    Dr Maria João Matos

  131. Chalcone-based derivatives as new scaffolds for h A3 adenosine receptor antagonists

    Article • Journal of Pharmacy and Pharmacology, January 2013, Oxford University Press (OUP)

    Dr Maria João Matos, Professor Fernanda Borges

  132. Synthesis and Structure-Activity Relationships of Novel Amino/Nitro Substituted 3-Arylcoumarins as Antibacterial Agents

    Article • Molecules, January 2013, MDPI AG

    Dr Maria João Matos

  133. Synthesis of coumarin–chalcone hybrids and evaluation of their antioxidant and trypanocidal properties

    Article • MedChemComm, January 2013, Royal Society of Chemistry

    Dr Maria João Matos

  134. New hydroxylated 3-arylcoumarins, synthesis and electrochemical study

    Article • Journal of Electroanalytical Chemistry, January 2013, Elsevier

    Dr Maria João Matos

  135. Targeting adenosine receptors with coumarins: synthesis and binding activities of amide and carbamate derivatives

    Article • Journal of Pharmacy and Pharmacology, December 2012, Oxford University Press (OUP)

    Dr Maria João Matos, Professor Fernanda Borges

  136. N-(2-Oxo-2H-chromen-3-yl)cyclohexanecarboxamide

    Article • Acta Crystallographica Section E Structure Reports Online, November 2012, International Union of Crystallography

    Dr Maria João Matos

  137. Looking for New Targets: Simple Coumarins as Antibacterial Agents

    Article • Medicinal Chemistry, November 2012, Bentham Science Publishers

    Dr Maria João Matos

  138. Editorial (Hot Topic: Monoamine Oxidase as a Target in Medicinal Chemistry and Drug Discovery)

    Article • Current Topics in Medicinal Chemistry, October 2012, Bentham Science Publishers

    Dr Maria João Matos

  139. Focusing on New Monoamine Oxidase Inhibitors: Differently Substituted Coumarins As An Interesting Scaffold

    Article • Current Topics in Medicinal Chemistry, October 2012, Bentham Science Publishers

    Dr Maria João Matos

  140. Monoamine Oxidase Inhibitors: Ten Years of Docking Studies

    Article • Current Topics in Medicinal Chemistry, October 2012, Bentham Science Publishers

    Dr Maria João Matos

  141. Looking for New Targets: Simple Coumarins as Antibacterial Agents

    Article • Medicinal Chemistry, September 2012, Bentham Science Publishers

    Dr Maria João Matos

  142. Monoamino Oxidase A: An Interesting Pharmacological Target for the Development of Multi-Target QSAR

    Article • Mini-Reviews in Medicinal Chemistry, September 2012, Bentham Science Publishers

    Dr Maria João Matos

  143. Lipodystrophy defined by Fat Mass Ratio in HIV-infected patients is associated with a high prevalence of glucose disturbances and insulin resistance

    Article • BMC Infectious Diseases, August 2012, Springer Science + Business Media

    Dr Maria João Matos, DAVIDE CARVALHO

  144. 3-Phenylcoumarin

    Article • Acta Crystallographica Section E Structure Reports Online, August 2012, International Union of Crystallography

    Dr Maria João Matos

  145. In search for new chemical entities as adenosine receptor ligands: Development of agents based on benzo-γ-pyrone skeleton

    Article • European Journal of Medicinal Chemistry, August 2012, Elsevier

    Dr Maria João Matos, Professor Fernanda Borges

  146. Antioxidant and Pro-Oxidant Effects of Polyphenolic Compounds and Structure-Activity Relationship Evidence

    Article • February 2012, IntechOpen

    Dr Maria João Matos

  147. Tyrosine-like condensed derivatives as tyrosinase inhibitors

    Article • Journal of Pharmacy and Pharmacology, February 2012, Oxford University Press (OUP)

    Dr Maria João Matos

  148. Structural Alerts for Predicting Clastogenic Activity of Pro-oxidant Flavonoid Compounds

    Article • SLAS DISCOVERY, February 2012, SAGE Publications

    Dr Maria João Matos

  149. Thyroid carcinoma in children and adolescents: A retrospective review

    Article • Endocrinología y Nutrición, February 2012, Elsevier

    Dr Maria João Matos

  150. 8-Substituted 3-Arylcoumarins as Potent and Selective MAO-B Inhibitors: Synthesis, Pharmacological Evaluation, and Docking Studies

    Article • ChemMedChem, January 2012, Wiley

    Professor Fernanda Borges, Dr Maria João Matos

  151. 3-Substituted coumarins as dual inhibitors of AChE and MAO for the treatment of Alzheimer's disease

    Article • MedChemComm, January 2012, Royal Society of Chemistry

    Dr Maria João Matos

  152. Improved Synthesis of 3-(Aminoaryl)coumarins

    Article • Organic Preparations and Procedures International, January 2012, Taylor & Francis

    Dr Maria João Matos, Professor Fernanda Borges

  153. Hydroxycoumarins as selective MAO-B inhibitors

    Article • Bioorganic & Medicinal Chemistry Letters, January 2012, Elsevier

    Dr Maria João Matos

  154. Synthesis and Study of a Series of 3-Arylcoumarins as Potent and Selective Monoamine Oxidase B Inhibitors

    Article • Journal of Medicinal Chemistry, October 2011, American Chemical Society (ACS)

    Dr Maria João Matos

  155. ChemInform Abstract: New Halogenated Phenylcoumarins as Tyrosinase Inhibitors.

    Article • ChemInform, October 2011, Wiley

    Dr Maria João Matos

  156. MAO inhibitory activity modulation: 3-Phenylcoumarins versus 3-benzoylcoumarins

    Article • Bioorganic & Medicinal Chemistry Letters, July 2011, Elsevier

    Dr Maria João Matos

  157. New halogenated phenylcoumarins as tyrosinase inhibitors

    Article • Bioorganic & Medicinal Chemistry Letters, June 2011, Elsevier

    Dr Maria João Matos

  158. ChemInform Abstract: Synthesis of 3‐Arylcoumarins via Suzuki Cross‐Coupling Reactions of 3‐Chlorocoumarin.

    Article • ChemInform, May 2011, Wiley

    Dr Maria João Matos, Professor Fernanda Borges

  159. Synthesis of 3-arylcoumarins via Suzuki-cross-coupling reactions of 3-chlorocoumarin

    Article • Tetrahedron Letters, March 2011, Elsevier

    Dr Maria João Matos, Professor Fernanda Borges

  160. New halogenated 3-phenylcoumarins as potent and selective MAO-B inhibitors

    Article • Bioorganic & Medicinal Chemistry Letters, September 2010, Elsevier

    Dr Maria João Matos, Professor Fernanda Borges

  161. Regioselective Synthesis of Bromo-Substituted 3-Arylcoumarins

    Article • Synthesis, June 2010, Thieme Publishing Group

    Dr Maria João Matos

  162. ChemInform Abstract: A New Series of 3‐Phenylcoumarins as Potent and Selective MAO‐B Inhibitors.

    Article • ChemInform, October 2009, Wiley

    Dr Maria João Matos

  163. Synthesis and evaluation of 6-methyl-3-phenylcoumarins as potent and selective MAO-B inhibitors

    Article • Bioorganic & Medicinal Chemistry Letters, September 2009, Elsevier

    Dr Maria João Matos

  164. Tyrosinase Inhibitor Activity of Coumarin-Resveratrol Hybrids

    Article • Molecules, July 2009, MDPI AG

    Dr Maria João Matos

  165. Synthesis of Regioisomeric Functionalized Benzodifurans and Angelicins

    Article • Helvetica Chimica Acta, July 2009, Wiley

    Dr Maria João Matos

  166. A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors

    Article • Bioorganic & Medicinal Chemistry Letters, June 2009, Elsevier

    Dr Maria João Matos

  167. Silicones—A Key Ingredient in Cosmetic and Toiletry Formulations

    Article • November 2005, Taylor & Francis

    Dr Maria João Matos