All Stories

  1. Cannabinoid-based Anti-cancer Strategies: Slowly Approaching the Bedside
  2. An Overview on Medicinal Chemistry of Synthetic and Natural Derivatives of Cannabidiol
  3. New pyridazinone-4-carboxamides as new cannabinoid receptor type-2 inverse agonists: Synthesis, pharmacological data and molecular docking
  4. New Methods for the Synthesis of Cannabidiol Derivatives
  5. Synthesis of a novel CB2 cannabinoid-porphyrin conjugate based on an antitumor chromenopyrazoledione
  6. Targeting Cannabinoid CB2 Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders
  7. GPR55 Review
  8. Exploring the Benzimidazole Ring as a Substitution for Indole in Cannabinoid Allosteric Modulators
  9. Cannabinoid receptor 2 (CB2) agonists and antagonists: a patent update
  10. Allosteric Modulators of the CB1Cannabinoid Receptor: A Structural Update Review
  11. Benzyl-1,2,4-triazoles as CB1Cannabinoid Receptor Ligands: Preparation andIn VitroPharmacological Evaluation
  12. Compounds combining pharmacophoric elements of CB1 and opioid mu.
  13. Ghrelin-Induced Orexigenic Effect in Rats Depends on the Metabolic Status and Is Counteracted by Peripheral CB1 Receptor Antagonism
  14. Description of a Bivalent Cannabinoid Ligand with Hypophagic Properties
  15. Tautomerism of hydroxychromenopyrazoles
  16. Anti-obesity efficacy of LH-21, a cannabinoid CB1 receptor antagonist with poor brain penetration, in diet-induced obese rats
  17. Inside Back Cover: Chromenopyrazoles: Non-psychoactive and Selective CB1Cannabinoid Agonists with Peripheral Antinociceptive Properties (ChemMedChem 3/2012)
  18. Chromenopyrazoles: Non-psychoactive and Selective CB1Cannabinoid Agonists with Peripheral Antinociceptive Properties
  19. Determination of the absolute configuration of 1,3,5-triphenyl-4,5-dihydropyrazole enantiomers by a combination of VCD, ECD measurements, and theoretical calculations
  20. ChemInform Abstract: Use of the Chlorophyll Derivative, Purpurin-18, for Syntheses of Sensitizers for Use in Photodynamic Therapy.
  21. ChemInform Abstract: Synthesis and Molecular Structure of 3-(2-Benzyloxy-6-hydroxyphenyl)-5-styrylpyrazoles. Reaction of 2-Styrylchromones and Hydrazine Hydrate.
  22. ChemInform Abstract: 1,3-Dipolar Cycloaddition of 3-Azido-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose and C60.
  23. ChemInform Abstract: Novel Derivatives of 3-Alkyl-1,5-diaryl-1H-1,2,4-triazoles and Their Pharmacological Evaluation as CB1Cannabinoid Ligands.
  24. Antiobesity designed multiple ligands: Synthesis of pyrazole fatty acid amides and evaluation as hypophagic agents
  25. Analgesic activity and pharmacological characterization of N-[1-phenylpyrazol-3-yl]-N-[1-(2-phenethyl)-4-piperidyl] propenamide, a new opioid agonist acting peripherally
  26. Novel derivatives of 3-alkyl-1,5-diaryl-1H-1,2,4-triazoles and their pharmacological evaluation as CB1 cannabinoid ligands
  27. CB1 Cannabinoid Antagonists: Structure-Activity Relationships and Potential Therapeutic Applications
  28. Synthesis and Pharmacological Evaluation of Chlorinated N-Alkyl-3- and -5-(2-hydroxyphenyl)pyrazoles as CB 1 Cannabinoid Ligands
  29. Synthesis and pharmacological studies of new hybrid derivatives of fentanyl active at the μ-opioid receptor and I2–imidazoline binding sites
  30. Antiobesity effects of the novel in vivo neutral cannabinoid receptor antagonist 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole – LH 21
  31. Structural—Activity Relationship Study on C-4 Carbon Atom of the CB1 Antagonist SR141716: Synthesis and Pharmacological Evaluation of 1,2,4-Triazole-3-carboxamides.
  32. Dynamic NMR Study of the Mechanisms of Double, Triple, and Quadruple Proton and Deuteron Transfer in Cyclic Hydrogen Bonded Solids of Pyrazole Derivatives
  33. Study of the Structure of 1-Hydroxymethylindazole and 1-Hydroxymethylbenzotriazole by X-Ray Crystallography, Multinuclear NMR in Solution and DFT Calculations.
  34. Discovery of 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole, a Novel in Vivo Cannabinoid Antagonist Containing a 1,2,4-Triazole Motif
  35. Fentanyl Derivatives Bearing Aliphatic Alkaneguanidinium Moieties: A New Series of Hybrid Molecules with Significant Binding Affinity for μ‐Opioid Receptors and I2‐Imidazoline Binding Sites.
  36. Study of the structure of 1-hydroxymethylindazole and 1-hydroxymethylbenzotriazole by X-ray crystallography, multinuclear NMR in solution and DFT calculations
  37. Fentanyl derivatives bearing aliphatic alkaneguanidinium moieties: a new series of hybrid molecules with significant binding affinity for μ-opioid receptors and I2-imidazoline binding sites
  38. Multiple hydrogen bonds and tautomerism in naphthyridine derivatives
  39. The Structure of Two 1-(Nitrophenyl)-Δ2-pyrazolines: a Crystallographic and Theoretical Study
  40. The structure of 1,1,3-trimethyl-Δ2- pyrazolinium perchlorate: An X-ray crystallographic and GIAO/DFT multinuclear NMR study
  41. Cannabinoids and Neuropathic Pain
  42. Structure of a 4-Nitroso-5-aminopyrazole and Its Salts:  Tautomerism, Protonation, andE/ZIsomerism
  43. 1,2,4,5-Tetrazines vs. Carboxylic Acid Dimers: Molecular Chemistry vs. Supramolecular Chemistry
  44. The structure of the agrochemical fungicidal 4-chloro-3-(3,5-dichlorophenyl)-1H-pyrazole (RPA 406194) and related compounds
  45. Fentanyl and Its Analogue N-(1-Phenylpyrazol-3-yl)-N-[1-(2-phenylethyl)-4-piperidyl]propanamide: 1H- and 13C-NMR Spectroscopy, X-Ray Crystallography, and Theoretical Calculations
  46. An experimental (NMR) and theoretical (GIAO) study of the tautomerism of benzotriazole in solution
  47. Synthesis and opioid activity of new fentanyl analogs
  48. ChemInform Abstract: Guanidinium and Aminoimidazolinium Derivatives of N‐(4‐Piperidyl)propanamides as Potential Ligands for μ Opioid and I2‐Imidazoline Receptors: Synthesis and Pharmacological Screening.
  49. Guanidinium and aminoimidazolinium derivatives of N-(4-piperidyl)propanamides as potential ligands for μ opioid and I2-imidazoline receptors: synthesis and pharmacological screening
  50. Long-Acting Fentanyl Analogues: Synthesis and Pharmacology of N-(1-Phenylpyrazolyl)-N-(1-phenylalkyl-4-piperidyl)propanamides
  51. Synthesis, X-ray Structure, and Properties of 2-(1‘-Pyridin-2‘-one)Benzimidazole
  52. A Solid-State NMR, X-ray Diffraction, and ab Initio Computational Study of Hydrogen-Bond Structure and Dynamics of Pyrazole-4-Carboxylic Acid Chains
  53. Crystal structure of 1,3,5-triphenyl-2-pyrazoline: a case of spontaneous resolution
  54. Recent advances in cannabinoid receptor agonists and antagonists
  55. Basicity of 1‐nitroaryl‐4,5‐dihydropyrazoles: pK a ­measurements and theoretical calculations
  56. Basicity of 1-nitroaryl-4,5-dihydropyrazoles: pKa �measurements and theoretical calculations
  57. 4‐Nitropyrazole: a nitrogen or an oxygen base in the gas phase?
  58. 4-Nitropyrazole: a nitrogen or an oxygen base in the gas phase?
  59. Synthesis and molecular structure of 3-(2-benzyloxy-6-hydroxyphenyl)-5-styrylpyrazoles. Reaction of 2-styrylchromones and hydrazine hydrate
  60. The search for proton mobility in solid pyrazoles: molecular and crystal structure of 3(5)-phenyl-4-bromo-5(3)-methylpyrazole
  61. A structural study of pyrazole-1-carboxamides by X-ray crystallography and 13C CPMAS NMR spectroscopy
  62. 1,3-Dipolar Cycloaddition of 3-Azido-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose and C60
  63. Hydrogen Bond Compression during Triple Proton Transfer in Crystalline Pyrazoles. A Dynamic15N NMR Study
  64. Packing Modes in Eight 3-Ethoxycarbonylpyrazole Derivatives. Influence of the Substituents on the Crystal Structure and Annular Tautomerism
  65. Synthesis and X-ray crystallographic study of 6,12-epiiminodibenzo[b,f][1,5]diazocines
  66. Pyridinium betaines derived from thiazolo and imidazoacridinones
  67. Structure of 3-nitropyrazole in solution and in the solid state
  68. Synthesis and molecular structure of new O/N/O ligands: Bis-phenol-pyridine and bis-phenol-pyrazole
  69. Solid-state structure of NH-pyrazolium hydrochlorides and hydrobromides by X-ray crystallography and CPMAS NMR
  70. 1H and13C NMR study of perdeuterated pyrazoles
  71. The Unusual Properties of 5-Methyl-4,5,6,7-Tetrahydro-1H-Indazole in the Solid State
  72. Molecular structure of 4-(3,5-dimethylpyrazol-1-yl)benzoic acid trifluoroacetate
  73. 19F,31P,1H NMR and X-ray crystallographic studies of (pentafluorophenyl)3−n (4-pyrazol-1-yl-2,3,5,6-tetrafluorophenyl) n=1,2,3 Phosphines
  74. Reaction of 2-azidobenzothiazole and 1-azido-4-(3′,5′-dimethyl-1′-pyrazolyl)tetrafluorobenzene with [60]fullerene and characterization of the adducts by fast-atom bombardment mass spectrometry
  75. Syntheses and preliminary in vivo photodynamic efficacy of benzoporphyrin derivatives from phylloerythrin and rhodoporphyrin XV methyl esters and aspartyl amides
  76. Molecular structure of 4-p-hydroxyphenyl-3,5-dimethylpyrazole monohydrate
  77. Gas-phase (ion cyclotron resonance spectrometric) and solid-state (crystallographic) studies of highly substituted pyrazoles
  78. Synthesis, structure (NMR and mass spectrometry) and conformational analysis of heterocyclic analogues of dibenzo[a,e]cycloocta-1,5-diene: 5,6,12,13-tetrahydrobispyrazolo[1,2-a:1′,2′-e][1,2,5,6]tetraazocinediium dihalides
  79. Cycloaddition of tetracyanoethene oxide with [60]fullerene
  80. New synthetic approaches to condensed pyridazinones: alkylpyridazinyl carbonitriles as building blocks for the synthesis of condensed pyridazinones
  81. Synthesis and1H,19F NMR spectroscopic characterization of (pentafluorophenyl)3-n(pyrazol-1-yl-tetrafluorophenyl)n=1,2porphyrins
  82. Synthesis, spectroscopic and electrochemical properties of tetrazolatomanganese(III) porphyrins
  83. The X-ray crystal and molecular structure of 3,5-di-tert-butylpyrazole hydrochloride at 200 K
  84. Photosensitization with derivatives of chlorin p6
  85. Structure and Dynamics of 3,5-Di-tert-butylpyrazole Probed by Combined X-ray Crystallography and 15N Solid State NMR
  86. Solid state structure of NH-pyrazoles not easily amenable to crystal structure determinations: The case of 3(5)-phenyl-5(3)-methylpyrazole and 3,5-diphenyl-4-methylpyrazole
  87. TRIFLUOROMETHYL AND PERFLUOROALKYL DERIVATIVES OF AZOLES. A REVIEW
  88. The Colors of C60 Solutions
  89. Die Farben von C60-Lösungen
  90. Aromatic propellenes. Part 1. NMR spectroscopy, X-ray crystal and molecular structure of hexa(3,5-dimethylpyrazol-1-yl)benzene
  91. Microwave spectra and ab initio calculations of 1-nitropyrazole
  92. 15N NMR chemical shifts of NH-pyrazoles in the solid state and in solution at low temperature
  93. Regioselective synthesis of the homochiral ligand (4S,7R)-7,8,8-trimethyl-4,5,6,7-tetrahydro-4,7-methanoindazol-2-yl-indazol-1′-ylmethane
  94. FAILED ATTEMPT TO INDUCE CHIRALITY USING A MAGNETIC FIELD: THE CASE OF CHIRAL HELICITY OF TRIS-(2-METHYLBENZIMIDAZOL-1-YL)METHANE
  95. Efficient syntheses of new classes of regiochemically pure benzoporphyrin derivatives
  96. Use of the chlorophyll derivative, purpurin-18, for syntheses of sensitizers for use in photodynamic therapy
  97. Synthesis, spectroscopic and electrochemical characterization of different isomer types in tetrazolatoindium(III) porphyrins
  98. ChemInform Abstract: Synthesis and Characterization of Bis(phenyltetrazolato)-germanium(IV) and -tin(IV) Porphyrins.
  99. Synthesis and characterization of bis(phenyltetrazolato)-germanium(IV) and -tin(IV) porphyrins