Professor Willem H. Koppenol

Superoxide does not react with hydrogen peroxide.

• Free Radical Biology and Medicine
• December 2019

The iron bolt is an award given during the Gordon Oxyradical Conference.

• Free Radical Biology and Medicine
• August 2018

Peroxynitrite forms very rapidly an adduct with CO2, which decays by reacting with a 2n...

• Chemical Research in Toxicology
• July 2018

Discovery and importance of hydrogen peroxide

• Nature
• July 2018

Rapid reduction of the oxyform of cytochrome P450 by a hydrated electron

• Journal of Biological Chemistry
• November 2017

Autoxidation of NO

• Inorganic Chemistry
• April 2017

Introduction for the special issue on the chemistry of redox signaling

• Archives of Biochemistry and Biophysics
• March 2017

Limits on the reactions of sulfur-containing biomolecules

• Archives of Biochemistry and Biophysics
• March 2017

Element names

• January 2017

Electrode Potentials ofl-Tryptophan,l-Tyrosine, 3-Nitro-l-tyrosine, 2,3-Difluoro-l-tyro...

• Biochemistry
• May 2016

The title says it all.

• Pure and Applied Chemistry
• April 2016

History of hydrogen peroxide

• Archives of Biochemistry and Biophysics
• April 2016

Primary photochemistry of peroxynitrite in aqueous solution

• Chemical Physics Letters
• November 2015

Superoxide-mediated post-translational modification of tyrosine residues

• Free Radical Biology and Medicine
• September 2015

Corrigendum to “Rapid reaction of superoxide with insulin-tyrosyl radicals to generate ...

• Free Radical Biology and Medicine
• May 2015

Redox Properties and Activity of Iron–Citrate Complexes: Evidence for Redox Cycling

• Chemical Research in Toxicology
• April 2015

Protein thiyl radical reactions and product formation: a kinetic simulation

• Free Radical Biology and Medicine
• March 2015

Concurrent Cooperativity and Substrate Inhibition in the Epoxidation of Carbamazepine b...

• Biochemistry
• January 2015

Standard electrode potentials involving radicals in aqueous solution: inorganic radical...

• Pure and Applied Chemistry
• January 2015

Iron(II) binding by cereal beta-glucan

• Carbohydrate Polymers
• January 2015

ONOOH does not react with H2: Potential beneficial effects of H2 as an antioxidant by s...

• Free Radical Biology and Medicine
• October 2014

Why Selenocysteine Replaces Cysteine in Thioredoxin Reductase: A Radical Hypothesis

• Biochemistry
• August 2014

Rapid reaction of superoxide with insulin-tyrosyl radicals to generate a hydroperoxide ...

• Free Radical Biology and Medicine
• May 2014

The kinetics of the reaction of nitrogen dioxide with iron(II)- and iron(III) cytochrome c

• Free Radical Biology and Medicine
• April 2014

Intramolecular 1,2- and 1,3-Hydrogen Transfer Reactions of Thiyl Radicals

• Israel Journal of Chemistry
• March 2014

Repair of Protein Radicals by Antioxidants

• Israel Journal of Chemistry
• March 2014

The complex interplay of iron metabolism, reactive oxygen species, and reactive nitroge...

• Free Radical Biology and Medicine
• December 2013

Cytochrome c and superoxide

• JBIC Journal of Biological Inorganic Chemistry
• July 2013

Reactions of the tetraoxidosulfate(˙−) and hydroxyl radicals with poly(sodium α-methyls...

• Physical Chemistry Chemical Physics
• January 2013

Decomposition kinetics of peroxynitrite: influence of pH and buffer

• Dalton Transactions
• January 2013

Standard electrode potentials involving radicals in aqueous solution: inorganic radicals

• BioInorganic Reaction Mechanisms
• January 2013

Efficient depletion of ascorbate by amino acid and protein radicals under oxidative stress

• Free Radical Biology and Medicine
• October 2012

Hydrogen Exchange Equilibria in Thiols

• Chemical Research in Toxicology
• September 2012

Chemical Characterization of the Smallest S -Nitrosothiol, HSNO; Cellular Cross-talk o...

• Journal of the American Chemical Society
• July 2012

Nitrosation, Thiols, and Hemoglobin: Energetics and Kinetics

• Inorganic Chemistry
• May 2012

Reversible Hydrogen Transfer Reactions in Thiyl Radicals From Cysteine and Related Mole...

• The Journal of Physical Chemistry
• May 2012

Fast repair of protein radicals by urate

• Free Radical Biology and Medicine
• May 2012

Peroxynitrous acid: controversy and consensus surrounding an enigmatic oxidant

• Dalton Transactions
• January 2012

Kinetic Simulation of the Chemical Stabilization Mechanism in Fuel Cell Membranes Using...

• Journal of The Electrochemical Society
• January 2012

Erratum: Otto Warburg's contributions to current concepts of cancer metabolism

• Nature Reviews Cancer
• July 2011

Otto Warburg's contributions to current concepts of cancer metabolism

• Nature Reviews Cancer
• April 2011

Reaction of SO4˙− with an oligomer of poly(sodium styrene sulfonate). Probing the mecha...

• Physical Chemistry Chemical Physics
• January 2011

Water increases rates of epoxidation by Mn(iii)porphyrins/imidazole/IO4− in CH2Cl2. Ana...

• Dalton Transactions
• January 2011

Radicals in Fuel Cell Membranes: Mechanisms of Formation and Ionomer Attack

• January 2011

Radical (HO●, H● and HOO●) Formation and Ionomer Degradation in Polymer Electrolyte Fue...

• Journal of The Electrochemical Society
• January 2011

Distance-Dependent Diffusion-Controlled Reaction of•NO and O2•−at Chemical Equilibrium ...

• The Journal of Physical Chemistry
• December 2010

Hydrogen Exchange Equilibria in Glutathione Radicals: Rate Constants

• Chemical Research in Toxicology
• October 2010

Selenium and Sulfur in Exchange Reactions: A Comparative Study

• The Journal of Organic Chemistry
• October 2010

Electrode potentials of partially reduced oxygen species, from dioxygen to water

• Free Radical Biology and Medicine
• August 2010

Reduction of protein radicals by GSH and ascorbate: potential biological significance

• Amino Acids
• June 2010

Why do proteins use selenocysteine instead of cysteine?

• Amino Acids
• May 2010

Damage to fuel cell membranes. Reaction of HO˙ with an oligomer of poly(sodium styrene ...

• Physical Chemistry Chemical Physics
• January 2010

Photon-Initiated Homolysis of Peroxynitrous Acid

• Inorganic Chemistry
• August 2009

Intermediates in the Autoxidation of Nitrogen Monoxide

• Chemistry - A European Journal
• June 2009

Efficient repair of protein radicals by ascorbate

• Free Radical Biology and Medicine
• April 2009

Peroxynitrate is formed rapidly during decomposition of peroxynitrite at neutral pH

• Dalton Transactions
• January 2009

Preparation and Properties of Lithium and Sodium Peroxynitrite

• Chemical Research in Toxicology
• December 2008

Reversible Intramolecular Hydrogen Transfer between Cysteine Thiyl Radicals and Glycine...

• The Journal of Physical Chemistry
• November 2008

Kinetics of Tyrosyl Radical Reduction by Selenocysteine

• Biochemistry
• September 2008

Antioxidant Nanoreactor Based on Superoxide Dismutase Encapsulated in Superoxide-Permea...

• The Journal of Physical Chemistry
• July 2008

Homolysis of the Peroxynitrite Anion Detected with Permanganate

• Inorganic Chemistry
• December 2007

Two Pathways of Carbon Dioxide Catalyzed Oxidative Coupling of Phenol by Peroxynitrite

• Chemical Research in Toxicology
• December 2007

Oxygen Activation by Cytochrome P450:  A Thermodynamic Analysis

• Journal of the American Chemical Society
• August 2007

The glutathione thiyl radical does not react with nitrogen monoxide

• Biochemical and Biophysical Research Communications
• August 2007

Fenton Chemistry and Iron Chelation under Physiologically Relevant Conditions:  Electro...

• Chemical Research in Toxicology
• October 2006

Oxidation-state-dependent reactions of cytochrome c with the trioxidocarbonate(•1−) rad...

• JBIC Journal of Biological Inorganic Chemistry
• September 2006

Catalysis of Electron Transfer by Selenocysteine †

• Biochemistry
• May 2006

Two Pathways of Carbon Dioxide Catalyzed Oxidative Coupling of Phenol by Peroxynitrite

• Chemical Research in Toxicology
• March 2006

Dissociation of CP20 from Iron(II)(cp20)3: A Pulse Radiolysis Study

• European Journal of Inorganic Chemistry
• February 2006

The kinetics of oxidation of GSH by protein radicals

• Biochemical Journal
• December 2005

Redox cycling of iron complexes of N-(dithiocarboxy)sarcosine and N-methyl-d-glucamine ...

• Free Radical Biology and Medicine
• December 2005

Corrigendum to “Kinetics properties of Cu,Zn-superoxide dismutase as a function of meta...

• Archives of Biochemistry and Biophysics
• December 2005

Peroxynitrite efficiently mediates the interconversion of redox intermediates of myelop...

• Biochemical and Biophysical Research Communications
• November 2005

Inhibition of the Fenton reaction by nitrogen monoxide

• JBIC Journal of Biological Inorganic Chemistry
• October 2005

Kinetics properties of Cu,Zn-superoxide dismutase as a function of metal content

• Archives of Biochemistry and Biophysics
• July 2005

Chemiluminescence of Pholasin caused by peroxynitrite

• Free Radical Biology and Medicine
• April 2005

On the Chemical and Electrochemical One-Electron Reduction of Peroxynitrous Acid

• The Journal of Physical Chemistry A
• February 2005

Peroxynitritometal complexes

• Coordination Chemistry Reviews
• February 2005

The history of naming elements.

• Helvetica Chimica Acta
• January 2005

Qualitative and Quantitative Determination of Nitrite and Nitrate with Ion Chromatography

• January 2005

Intramolecular addition of cysteine thiyl radicals to phenylalanine in peptides: format...

• Chemical Communications
• January 2005

Calmodulin methionine residues are targets for one-electron oxidation by hydroxyl radic...

• Chemical Communications
• January 2005

Redox Properties of the Iron Complexes of Orally Active Iron ChelatorsCP20, CP502, CP50...

• Helvetica Chimica Acta
• December 2004

Preventing Nitrite Contamination in Tetramethylammonium Peroxynitrite Solutions

• Inorganic Chemistry
• October 2004

UV Photolysis of 3-Nitrotyrosine Generates Highly Oxidizing Species:  A Potential Sourc...

• Chemical Research in Toxicology
• September 2004

Kinetics Evidence for a Complex between Peroxynitrous Acid and Titanium(IV)

• Inorganic Chemistry
• August 2004

Human peroxiredoxin 5 is a peroxynitrite reductase

• FEBS Letters
• July 2004

The mechanisms of S-nitrosothiol decomposition catalyzed by iron

• Nitric Oxide
• March 2004

Mechanistic insight into the peroxidase catalyzed nitration of tyrosine derivatives by ...

• European Journal of Biochemistry
• February 2004

Peroxynitrous Acid - Where is the Hydroxyl Radical?

• IUBMB Life
• January 2004

Rapid scavenging of peroxynitrous acid by monohydroascorbate

• Free Radical Biology and Medicine
• December 2003

Evaluation of Activation Volumes for the Conversion of Peroxynitrous to Nitric Acid

• The Journal of Physical Chemistry A
• December 2003

Peroxynitrite-mediated oxidation of dichlorodihydrofluorescein and dihydrorhodamine

• Free Radical Biology and Medicine
• September 2003

Oxidation of Nitrite by Peroxynitrous Acid

• The Journal of Physical Chemistry A
• March 2003

Erratum to “NO Nomenclature?” [Nitric Oxide 6 (2002), 96–98]

• Nitric Oxide
• November 2002

The Rate Constant of the Reaction of Superoxide with Nitrogen Monoxide:  Approaching th...

• The Journal of Physical Chemistry A
• April 2002

The Haber-Weiss cycle—71 years later

• Redox Report
• February 2002

NO Nomenclature?

• Nitric Oxide
• February 2002

Product Distribution of Peroxynitrite Decay as a Function of pH, Temperature, and Conce...

• Journal of the American Chemical Society
• January 2002

Studies of metal-binding properties of Cu,Zn superoxide dismutase by isothermal titrati...

• January 2002

Naming of new elements(IUPAC Recommendations 2002)

• Pure and Applied Chemistry
• January 2002

100 Years of peroxynitrite chemistry and 11 years of peroxynitrite biochemistry

• Redox Report
• December 2001

Hydrolysis and Photolysis of Tris(tetraethylammonium) Pentacyanoperoxynitritocobaltate(...

• Helvetica Chimica Acta
• October 2001

Oxidation of NADH by Chloramines and Chloramides and Its Activation by Iodide and by Te...

• Archives of Biochemistry and Biophysics
• September 2001

The Haber-Weiss cycle – 70 years later

• Redox Report
• August 2001

Reaction of peroxynitrite with carbon dioxide: intermediates and determination of the y...

• JBIC Journal of Biological Inorganic Chemistry
• July 2001

On the Oxidation of Cytochrome c by Hypohalous Acids

• Archives of Biochemistry and Biophysics
• May 2001

Gibbs Energy of Formation of Peroxynitrite

• Chemical Research in Toxicology
• April 2001

Names for muonium and hydrogen atoms and their ions(IUPAC Recommendations 2001)

• Pure and Applied Chemistry
• January 2001

Reactions of Peroxynitrite with Phenolic and Carbonyl Compounds: Flavonoids are not Sca...

• Helvetica Chimica Acta
• September 2000

Peroxynitrite does not decompose to singlet oxygen (1Delta gO2) and nitroxyl (NO-)

• Proceedings of the National Academy of Sciences
• September 2000

On the Irreversible Destruction of Reduced Nicotinamide Nucleotides by Hypohalous Acids

• Archives of Biochemistry and Biophysics
• August 2000

The Preparation of Apo-Cu,Zn Superoxide Dismutase by Ion-Exchange Chromatography on Imi...

• Protein Expression and Purification
• June 2000

The Quantitative Oxidation of Methionine to Methionine Sulfoxide by Peroxynitrite

• Archives of Biochemistry and Biophysics
• May 2000

Mechanism of Reaction of Myeloperoxidase with Nitrite

• Journal of Biological Chemistry
• April 2000

Synthesis and Characterization of Tris(tetraethylammonium) Pentacyanoperoxynitritocobal...

• Helvetica Chimica Acta
• April 2000

Names for inorganic radicals (IUPAC Recommendations 2000)

• Pure and Applied Chemistry
• January 2000

• Helvetica Chimica Acta
• May 1999

Conformation of Peroxynitrite:  Determination by Crystallographic Analysis

• Chemical Research in Toxicology
• April 1999

Correspondence

• Free Radical Biology and Medicine
• March 1999

[36] Peroxynitrite studied by stopped-flow spectroscopy

• January 1999

Kinetic Study of the Reaction of Glutathione Peroxidase with Peroxynitrite

• Chemical Research in Toxicology
• December 1998

Peroxynitrite Uncloaked? Volume 11, Number 7, July 1998, pp 716−717

• Chemical Research in Toxicology
• November 1998

The basic chemistry of nitrogen monoxide and peroxynitrite

• Free Radical Biology and Medicine
• September 1998

Peroxynitrite Uncloaked?

• Chemical Research in Toxicology
• July 1998

The chemistry of peroxynitrite, a biological toxin<a name=TOP1></a>

• Química Nova
• June 1998

Formation and Properties of Peroxynitrite as Studied by Laser Flash Photolysis, High-Pr...

• Chemical Research in Toxicology
• May 1998

The Reaction of Peroxynitrite with Zeaxanthin

• Nitric Oxide
• February 1998

Can ONOOH Undergo Homolysis?

• Chemical Research in Toxicology
• February 1998

Hydrogen Isotope Effect on the Isomerization of Peroxynitrous Acid

• Helvetica Chimica Acta
• January 1998

Formation and Properties of Peroxynitrite as Studied by Laser Flash Photolysis, High-Pr...

• Chemical Research in Toxicology
• November 1997

Kinetic study of the reaction of ebselen with peroxynitrite

• FEBS Letters
• December 1996

Reaction of peroxynitrite with L-tryptophan

• Redox Report
• June 1996

The enthalpy of isomerization of peroxynitrite to nitrate

• Thermochimica Acta
• February 1996

[27] Syntheses of peroxynitrite: To go with the flow or on solid grounds?

• January 1996

Nitration and Hydroxylation of Phenolic Compounds by Peroxynitrite

• Chemical Research in Toxicology
• January 1996

Ab Initio and NMR Study of Peroxynitrite and Peroxynitrous Acid:  Important Biological...

• The Journal of Physical Chemistry
• January 1996

Thermodynamics of reactions involving nitrogen-oxygen compounds

• January 1996

Say NO to nitric oxide: Nomenclature for nitrogen- and oxygen-containing compounds

• January 1996

[18] Nitration and hydroxylation of phenolic compounds by peroxynitrite

• January 1996

A Novel Hexanuclear FeIII-cis-Inositolato Complex as a Model for FeIII–Polyol Interacti...

• Angewandte Chemie International Edition in English
• November 1995

Ein neuartiger sechskerniger FeIII-cis-Inositolato-Komplex als Modell für FeIII-Polyol-...

• Angewandte Chemie
• October 1995

A practical method for preparing peroxynitrite solutions of low ionic strength and free...

• Free Radical Biology and Medicine
• January 1995

The kinetics of the oxidation of l-ascorbic acid by peroxynitrite

• Free Radical Biology and Medicine
• January 1995

Thermodynamic considerations on the formation of reactive species from hypochlorite, su...

• FEBS Letters
• June 1994

On the pH-dependent yield of hydroxyl radical products from peroxynitrite

• Free Radical Biology and Medicine
• March 1994

The hazard of hydroxyl radicals, a reply

• Free Radical Biology and Medicine
• February 1994

NO comments

• Nature
• January 1994

Chemistry of iron and copper in radical reactions

• January 1994

The centennial of the Fenton reaction

• Free Radical Biology and Medicine
• December 1993

The nitration and hydroxylation of phenol and salicylic acid by peroxynitrite

• Free Radical Biology and Medicine
• November 1993

ALS, SOD and peroxynitrite

• Nature
• August 1993

Ferredoxin binding site on ferredoxin: NADP+ reductase. Differential chemical modificat...

• European Journal of Biochemistry
• August 1993

Binding of ferredoxin to ferredoxin: NADP+oxidoreductase: The role of carboxyl groups, ...

• Protein Science
• July 1993

Ab initio calculations on ONOOH and ONOO?

• International Journal of Quantum Chemistry
• March 1993

A thermodynamic appraisal of the radical sink hypothesis

• Free Radical Biology and Medicine
• January 1993

Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide

• Chemical Research in Toxicology
• November 1992

The quality of nutrition letters in free radical biology & medicine: A reply

• Free Radical Biology and Medicine
• October 1992

A small point

• Free Radical Biology and Medicine
• August 1992

The hydroxylation of tryptophan

• Archives of Biochemistry and Biophysics
• August 1992

The hydroxylation of phenylalanine and tyrosine: A comparison with salicylate and trypt...

• Archives of Biochemistry and Biophysics
• August 1992

Spirohydantoin inhibitors of aldose reductase inhibit iron- and copper-catalysed ascorb...

• Biochemical Pharmacology
• August 1991

The superoxide dismutase activities of two higher-valent manganese complexes, MnIV desf...

• Archives of Biochemistry and Biophysics
• August 1991

Reactions of Fe(II)-ATP and Fe(II)-citrate complexes with t -butyl hydroperoxide and cu...

• FEBS Letters
• March 1991

TRANSITION METALS IN OXIDATIVE STRESS: AN OVERVIEW

• January 1991

CATALYSIS OF OXYRADICAL REACTIONS BY IRON COMPLEXES

• January 1991

Oxyradicals and multivitamin tablets

• Free Radical Biology and Medicine
• January 1991

Thermodynamic considerations on the generation of hydroxyl radicals from nitrous oxide—...

• Free Radical Biology and Medicine
• January 1991

Reactions of Fe(II)-ATP and Fe(II)-citrate complexes with t -butyl hydroperoxide and cu...

• FEBS Letters
• November 1990

Oxyradical reactions: from bond-dissociation energies to reduction potentials

• FEBS Letters
• May 1990

Reactions of iron(II) nucleotide complexes with hydrogen peroxide

• FEBS Letters
• February 1990

What is in a name? Rules for radicals

• Free Radical Biology and Medicine
• January 1990

Catalysis of oxyradical reactions by iron

• Free Radical Biology and Medicine
• January 1990

[12] Distinction between hydroxyl radical and ferryl species

• January 1990

The hydroxylation of the salicylate anion by a fenton reaction and Γ-radiolysis: A cons...

• Free Radical Biology and Medicine
• January 1990

Electron affinity of chlorine dioxide

• The Journal of Physical Chemistry
• December 1989

Hormesis

• Science
• October 1989

Electrostatic interactions of 4-carboxy-2,6-dinitrophenyllysine-modified cytochromes c ...

• Biochimica et Biophysica Acta (BBA) - Bioenergetics
• November 1988

The electron-transfer site of spinach plastocyanin

• Biochemistry
• August 1988

Reactions of iron(II) nitrilotriacetate and iron(II) ethylenediamine-N,N'-diacetate com...

• Journal of the American Chemical Society
• July 1988

Thermodynamics of reactions involving oxyradicals and hydrogen peroxide

• Bioelectrochemistry and Bioenergetics
• December 1987

Reduction potential of the carbon dioxide/carbon dioxide radical anion: a comparison wi...

• The Journal of Physical Chemistry
• July 1987

Effect of a dipole moment on the ionic strength dependence of electron-transfer reactio...

• Journal of the American Chemical Society
• April 1987

The reaction between ferrous polyaminocarboxylate complexes and hydrogen peroxide: An i...

• Journal of Inorganic Biochemistry
• March 1987

Effects of γ-irradiation on Isolated Rat Liver Mitochondria

• International Journal of Radiation Biology and Related Studies in Physics Chemistry and...
• January 1987

In vitro damage to rat lens by xanthine-xanthine oxidase: Protection by ascorbate

• Experimental Eye Research
• December 1986

Catalysis of superoxide dismutation by manganese aminopolycarboxylate complexes

• Archives of Biochemistry and Biophysics
• December 1986

Energetics of interconversion reactions of oxyradicals

• Advances in Free Radical Biology & Medicine
• January 1985

The reaction of ferrous EDTA with hydrogen peroxide: Evidence against hydroxyl radical ...

• Journal of Free Radicals in Biology & Medicine
• January 1985

The Radiation Chemistry of Cytochromec

• Israel Journal of Chemistry
• January 1984

The oxidizing nature of the hydroxyl radical. A comparison with the ferryl ion (FeO2+)

• The Journal of Physical Chemistry
• January 1984

Is cytochrome c reactivity determined by dipole moment or by local charges?

• Biophysical Chemistry
• October 1983

CHEMIOSMOTIC ATPase MECHANISMS

• Annals of the New York Academy of Sciences
• December 1982

The reduction potential of the couple O3 /O·− 3

• FEBS Letters
• April 1982

The Relation between the Dipole Moment of Cytochrome c and the Activity with Cytochrome...

• January 1982

Basic issues in binding

• Trends in Biochemical Sciences
• January 1981

Use of singly modified cytochrome c derivatives to determine the site for electron tran...

• Journal of the American Chemical Society
• January 1981

Effect of a molecular dipole on the ionic strength dependence of a biomolecular rate co...

• Biophysical Journal
• March 1980

THE HABER-WEISS CYCLE

• Photochemistry and Photobiology
• October 1978

The electric potential field around cytochrome c and the effect of ionic strength on re...

• Biochimica et Biophysica Acta (BBA) - Bioenergetics
• September 1978

A tunnelling model to explain the reduction of ferricytochrome c by H and OH radicals

• Biochimica et Biophysica Acta (BBA) - Bioenergetics
• July 1978

EFFECTS OF ANIONS ON THE REACTION BETWEEN CYTOCHROME c AND CYTOCHROME c OXIDASE

• January 1978

Mechanism of reactions involving singlet oxygen and the superoxide anion

• FEBS Letters
• November 1977

Mechanism of the reaction of hydrated electrons with ferrocytochrome c

• Biochimica et Biophysica Acta (BBA) - Bioenergetics
• February 1977

Erratum

• Nature
• November 1976

The kinetics of the reduction of cytochrome c by the superoxide anion radical

• Biochimica et Biophysica Acta (BBA) - Bioenergetics
• November 1976

Reactions involving singlet oxygen and the superoxide anion

• Nature
• July 1976

CHAPTER 1. Peroxynitrite: The Basics