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  1. Integrated cross-sectoral surveillance of antimicrobial resistance genotypes and phenotypes across disparate reservoirs

    Article • October 2025, Cold Spring Harbor Laboratory Press

    Professor Trevor Lithgow

  2. Telomere bacteriophages are widespread and equip their bacterial hosts with potent interbacterial weapons

    Article • Science Advances, May 2025, American Association for the Advancement of Science

    Professor Trevor Lithgow

  3. Ethical bioprospecting and microbial assessments for sustainable solutions to the AMR crisis

    Article • IUBMB Life, December 2024, Wiley

    Professor Trevor Lithgow

  4. A new model of endotracheal tube biofilm identifies combinations of matrix-degrading enzymes and antimicrobials able to eradicate biofilms of pathogens that cause ventilator-associated pneumonia

    Article • Microbiology, August 2024, Society for General Microbiology

    Professor Trevor Lithgow

  5. RIL-seq reveals extensive involvement of small RNAs in virulence and capsule regulation in hypervirulent Klebsiella pneumoniae

    Article • Nucleic Acids Research, May 2024, Oxford University Press (OUP)

    Professor Trevor Lithgow

  6. What does the future hold? Improved detection, treatment and management of One Health AMR

    Article • Microbiology Australia, May 2024, CSIRO Publishing

    Professor Trevor Lithgow

  7. The TAM, a Translocation and Assembly Module for protein assembly and potential conduit for phospholipid transfer

    Article • EMBO Reports, March 2024, Springer Science + Business Media

    Professor Trevor Lithgow

  8. A new model of endotracheal tube biofilm identifies combinations of matrix-degrading enzymes and antimicrobials able to eradicate biofilms of pathogens that cause ventilator-associated pneumonia

    Article • February 2024, Cold Spring Harbor Laboratory Press

    Professor Trevor Lithgow

  9. Surveying membrane landscapes: a new look at the bacterial cell surface

    Article • Nature Reviews Microbiology, February 2023, Springer Science + Business Media

    Professor Trevor Lithgow

  10. A Structurally Characterized Staphylococcus aureus Evolutionary Escape Route from Treatment with the Antibiotic Linezolid

    Article • Microbiology Spectrum, August 2022, ASM Journals

    Professor Trevor Lithgow

  11. Targeting bacterial outer-membrane remodelling to impact antimicrobial drug resistance

    Article • Trends in Microbiology, June 2022, Elsevier

    Professor Trevor Lithgow

  12. A noncanonical chaperone interacts with drug efflux pumps during their assembly into bacterial outer membranes

    Article • PLoS Biology, January 2022, PLOS

    Professor Trevor Lithgow

  13. Two-Step Receptor Binding Initiates Bacteriophage Infection of <i>Klebsiella Pneumoniae</i>

    Article • January 2022, Elsevier

    Professor Trevor Lithgow

  14. The Carbapenemase BKC-1 from Klebsiella pneumoniae Is Adapted for Translocation by Both the Tat and Sec Translocons

    Article • mBio, June 2021, ASM Journals

    Professor Trevor Lithgow

  15. Stepwise evolution of carbapenem-resistance, captured in patient samples and evident in global genomics of Klebsiella pneumoniae

    Article • June 2021, Cold Spring Harbor Laboratory Press

    Professor Trevor Lithgow

  16. AcrHub: an integrative hub for investigating, predicting and mapping anti-CRISPR proteins

    Article • Nucleic Acids Research, November 2020, Oxford University Press (OUP)

    Professor Trevor Lithgow

  17. AcrDB: a database of anti-CRISPR operons in prokaryotes and viruses

    Article • Nucleic Acids Research, October 2020, Oxford University Press (OUP)

    Professor Trevor Lithgow

  18. Forensic genomics of a novel Klebsiella quasipneumoniae type from a neonatal intensive care unit in China reveals patterns of colonization, evolution and epidemiology

    Article • Microbial Genomics, October 2020, Society for General Microbiology

    Professor Trevor Lithgow

  19. Single Molecule Localization Microscopy (SMLM) imaging of bacteria: A sample preparation guide

    Article • October 2020, Springer Science + Business Media

    Professor Trevor Lithgow

  20. Mapping bacterial effector arsenals: in vivo and in silico approaches to defining the protein features dictating effector secretion by bacteria

    Article • Current Opinion in Microbiology, October 2020, Elsevier

    Professor Trevor Lithgow

  21. The architecture and stabilisation of flagellotropic tailed bacteriophages

    Article • Nature Communications, July 2020, Springer Science + Business Media

    Professor Trevor Lithgow

  22. Formation and function of bacterial organelles

    Article • Nature Reviews Microbiology, July 2020, Springer Science + Business Media

    Professor Trevor Lithgow

  23. PaCRISPR: a server for predicting and visualizing anti-CRISPR proteins

    Article • Nucleic Acids Research, May 2020, Oxford University Press (OUP)

    Professor Trevor Lithgow

  24. The crystal structure of the TonB-dependent transporter YncD reveals a positively charged substrate-binding site

    Article • Acta Crystallographica Section D Structural Biology, April 2020, International Union of Crystallography

    Rhys Grinter, Professor Trevor Lithgow

  25. Forensic genomics of a novel Klebsiella quasipneumoniae type from an NICU in China reveals patterns of genetic diversity, evolution and epidemiology

    Article • March 2020, Cold Spring Harbor Laboratory Press

    Professor Trevor Lithgow

  26. The crystal structure of the TonB-dependent transporter YncD reveals a positively charged substrate binding site.

    Article • January 2020, Cold Spring Harbor Laboratory Press

    Professor Trevor Lithgow

  27. Protease-associated import systems are widespread in Gram-negative bacteria

    Article • PLoS Genetics, October 2019, PLOS

    Professor Trevor Lithgow, Rhys Grinter

  28. The flagellotropic bacteriophage YSD1 targets Salmonella Typhi with a Chi‐like protein tail fibre

    Article • Molecular Microbiology, October 2019, Wiley

    Professor Trevor Lithgow

  29. The structure of the iron-catecholate transporter Fiu suggests substrate import occurs via a 2-step mechanism

    Article • September 2019, Cold Spring Harbor Laboratory Press

    Professor Trevor Lithgow

  30. Determination of the molecular basis for coprogen import by Gram-negative bacteria

    Article • IUCrJ, April 2019, International Union of Crystallography

    Professor Trevor Lithgow, Rhys Grinter

  31. Filamentous phages: masters of a microbial sharing economy

    Article • EMBO Reports, April 2019, EMBO

    Professor Trevor Lithgow

  32. Positive-unlabelled learning of glycosylation sites in the human proteome

    Article • BMC Bioinformatics, March 2019, Springer Science + Business Media

    Professor Trevor Lithgow

  33. Master regulator could be key to controlling cancer progression

    Article • Molecular Cell, March 2019, Elsevier

    Professor Trevor Lithgow

  34. cryoEM-Guided Development of Antibiotics for Drug-Resistant Bacteria

    Article • ChemMedChem, February 2019, Wiley

    Professor Trevor Lithgow

  35. The TAM: A Translocation and Assembly Module of the β-barrel Assembly Machinery in Bacterial Outer Membranes

    Article • January 2019, ASM Journals

    Professor Trevor Lithgow

  36. Bastion3: a two-layer ensemble predictor of type III secreted effectors

    Article • Bioinformatics, November 2018, Oxford University Press (OUP)

    Professor Trevor Lithgow

  37. FusC, a member of the M16 protease family acquired by bacteria for iron piracy against plants

    Article • PLoS Biology, August 2018, PLOS

    Professor Trevor Lithgow

  38. Quokka: a comprehensive tool for rapid and accurate prediction of kinase family-specific phosphorylation sites in the human proteome

    Article • Bioinformatics, June 2018, Oxford University Press (OUP)

    Professor Trevor Lithgow

  39. An investigation into the Omp85 protein BamK in hypervirulent Klebsiella pneumoniae , and its role in outer membrane biogenesis

    Article • Molecular Microbiology, June 2018, Wiley

    Professor Trevor Lithgow

  40. Methionine biosynthesis and transport are functionally redundant for the growth and virulence ofSalmonellaTyphimurium

    Article • Journal of Biological Chemistry, May 2018, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Trevor Lithgow

  41. The WD40 Protein BamB Mediates Coupling of BAM Complexes into Assembly Precincts in the Bacterial Outer Membrane

    Article • Cell Reports, May 2018, Elsevier

    Professor Trevor Lithgow

  42. Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis

    Article • PLoS Pathogens, March 2018, PLOS

    Professor Trevor Lithgow

  43. Bastion6: a bioinformatics approach for accurate prediction of type VI secreted effectors

    Article • Bioinformatics, March 2018, Oxford University Press (OUP)

    Professor Trevor Lithgow

  44. Genome-scale metabolic modeling of responses to polymyxins in Pseudomonas aeruginosa

    Article • GigaScience, March 2018, Oxford University Press (OUP)

    Professor Trevor Lithgow

  45. Correction for Nguyen et al., “Bacteriophage Transcytosis Provides a Mechanism To Cross Epithelial Cell Layers”

    Article • mBio, January 2018, ASM Journals

    Jeremy Barr, Professor Trevor Lithgow

  46. The Structure of a Conserved Domain of TamB Reveals a Hydrophobic β Taco Fold

    Article • Structure, December 2017, Elsevier

    Professor Trevor Lithgow

  47. Systematic analysis and prediction of type IV secreted effector proteins by machine learning approaches

    Article • Briefings in Bioinformatics, November 2017, Oxford University Press (OUP)

    Professor Trevor Lithgow

  48. Bacteriophage Transcytosis Provides a Mechanism To Cross Epithelial Cell Layers

    Article • mBio, November 2017, ASM Journals

    Jeremy Barr, Kyle Schlosser, Benjamin S Padman, Professor Trevor Lithgow

  49. Constraints on lateral gene transfer in promoting fimbrial usher protein diversity and function

    Article • Open Biology, November 2017, Royal Society Publishing

    Professor Trevor Lithgow

  50. Phylogenetic Analysis of Klebsiella pneumoniae from Hospitalized Children, Pakistan

    Article • Emerging Infectious Diseases, November 2017, Centers for Disease Control and Prevention (CDC)

    Professor Trevor Lithgow

  51. Structure and Membrane Topography of the Vibrio-Type Secretin Complex from the Type 2 Secretion System of EnteropathogenicEscherichia coli

    Article • Journal of Bacteriology, October 2017, ASM Journals

    Professor Trevor Lithgow

  52. Reductive evolution in outer membrane protein biogenesis has not compromised cell surface complexity in Helicobacter pylori

    Article • MicrobiologyOpen, October 2017, Wiley

    Dr Rebecca J Gorrell, Professor Trevor Lithgow, Dr Rebecca Gorrell

  53. The TPR domain of BepA is required for productive interaction with substrate proteins and the β-barrel assembly machinery complex

    Article • Molecular Microbiology, October 2017, Wiley

    Yoshinori Akiyama, Shin-ichiro Narita, Professor Trevor Lithgow

  54. Structural Basis of Type 2 Secretion System Engagement between the Inner and Outer Bacterial Membranes

    Article • mBio, October 2017, ASM Journals

    Professor Trevor Lithgow

  55. Structural basis for substrate selection by the translocation and assembly module of the β-barrel assembly machinery

    Article • Molecular Microbiology, August 2017, Wiley

    Professor Trevor Lithgow, Prof Martin Jung

  56. Knowledge-transfer learning for prediction of matrix metalloprotease substrate-cleavage sites

    Article • Scientific Reports, July 2017, Nature

    Professor Trevor Lithgow

  57. Extensively Drug-Resistant Klebsiella pneumoniae Causing Nosocomial Bloodstream Infections in China: Molecular Investigation of Antibiotic Resistance Determinants, Informing Therapy, and Clinical Outcomes

    Article • Frontiers in Microbiology, June 2017, Frontiers

    Professor Trevor Lithgow

  58. Super-Resolution Imaging of Protein Secretion Systems and the Cell Surface of Gram-Negative Bacteria

    Article • Frontiers in Cellular and Infection Microbiology, May 2017, Frontiers

    Professor Trevor Lithgow

  59. POSSUM: a bioinformatics toolkit for generating numerical sequence feature descriptors based on PSSM profiles

    Article • Bioinformatics, May 2017, Oxford University Press (OUP)

    Professor Trevor Lithgow

  60. Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome

    Article • mBio, May 2017, ASM Journals

    Professor Trevor Lithgow

  61. The Assembly of Beta-Barrel Proteins into Bacterial Outer Membranes

    Article • Biophysical Journal, February 2017, Elsevier

    Professor Trevor Lithgow

  62. SecretEPDB: a comprehensive web-based resource for secreted effector proteins of the bacterial types III, IV and VI secretion systems

    Article • Scientific Reports, January 2017, Nature

    Professor Trevor Lithgow

  63. Defining Membrane Protein Localization by Isopycnic Density Gradients

    Article • January 2017, Springer Science + Business Media

    Professor Trevor Lithgow

  64. Comprehensive assessment and performance improvement of effector protein predictors for bacterial secretion systems III, IV and VI

    Article • Briefings in Bioinformatics, October 2016, Oxford University Press (OUP)

    Professor Trevor Lithgow

  65. GlycoMine struct : a new bioinformatics tool for highly accurate mapping of the human N-linked and O-linked glycoproteomes by incorporating structural features

    Article • Scientific Reports, October 2016, Nature

    Professor Trevor Lithgow

  66. The modular nature of the β-barrel assembly machinery, illustrated inBorrelia burgdorferi

    Article • Molecular Microbiology, September 2016, Wiley

    Professor Trevor Lithgow

  67. Effective assembly of fimbriae in Escherichia coli depends on the translocation assembly module nanomachine

    Article • Nature Microbiology, May 2016, Nature

    Professor Trevor Lithgow

  68. Conserved Features in the Structure, Mechanism, and Biogenesis of the Inverse Autotransporter Protein Family

    Article • Genome Biology and Evolution, May 2016, Oxford University Press (OUP)

    Professor Trevor Lithgow, Professor Anthony W Purcell

  69. Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis

    Article • Nature Microbiology, February 2016, Nature

    Mr Seong Hoong Chow, Professor Trevor Lithgow

  70. Antibiotic regimen based on population analysis of residing persister cells eradicates Staphylococcus epidermidis biofilms

    Article • Scientific Reports, December 2015, Nature

    Professor Trevor Lithgow

  71. Prebiotic-chemistry inspired polymer coatings for biomedical and material science applications

    Article • NPG Asia Materials, November 2015, Nature

    Professor Trevor Lithgow

  72. Molecular architecture of the active mitochondrial protein gate

    Article • Science, September 2015, American Association for the Advancement of Science

    Professor Trevor Lithgow

  73. Antibacterial poly(ethylene glycol) hydrogels from combined epoxy-amine and thiol-ene click reaction

    Article • Journal of Polymer Science Part A Polymer Chemistry, September 2015, Wiley

    Professor Trevor Lithgow

  74. Evidence of Distinct Channel Conformations and Substrate Binding Affinities for the Mitochondrial Outer Membrane Protein Translocase Pore Tom40

    Article • Journal of Biological Chemistry, September 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Trevor Lithgow

  75. Conserved features in TamA enable interaction with TamB to drive the activity of the translocation and assembly module

    Article • Scientific Reports, August 2015, Nature

    Professor Trevor Lithgow, Professor Martin J Scanlon

  76. Assembly of the secretion pores GspD, Wza and CsgG into bacterial outer membranes does not require the Omp85 proteins BamA or TamA

    Article • Molecular Microbiology, June 2015, Wiley

    Professor Anthony W Purcell, Professor Trevor Lithgow

  77. Evolution of the Translocation and Assembly Module (TAM)

    Article • Genome Biology and Evolution, May 2015, Oxford University Press (OUP)

    Professor Trevor Lithgow

  78. Positive Autoregulation ofmrkHIby the Cyclic Di-GMP-Dependent MrkH Protein in the Biofilm Regulatory Circuit of Klebsiella pneumoniae

    Article • Journal of Bacteriology, March 2015, ASM Journals

    Professor Trevor Lithgow

  79. Light-triggered release of ciprofloxacin from an in situ forming click hydrogel for antibacterial wound dressings

    Article • Journal of Materials Chemistry B, January 2015, Royal Society of Chemistry

    Professor Trevor Lithgow

  80. Identification of BamC on the Surface of E. coli

    Article • January 2015, Springer Science + Business Media

    Professor Trevor Lithgow

  81. Mitochondrial Biogenesis: Cell-Cycle-Dependent Investment in Making Mitochondria

    Article • Current Biology, January 2015, Elsevier

    Professor Trevor Lithgow

  82. The β-Barrel Assembly Machinery Complex

    Article • January 2015, Springer Science + Business Media

    Professor Trevor Lithgow

  83. Of linkers and autochaperones: an unambiguous nomenclature to identify common and uncommon themes for autotransporter secretion

    Article • Molecular Microbiology, November 2014, Wiley

    Professor Trevor Lithgow

  84. Reconstitution of a nanomachine driving the assembly of proteins into bacterial outer membranes

    Article • Nature Communications, October 2014, Nature

    Professor Trevor Lithgow

  85. Assembly of β-barrel proteins into bacterial outer membranes

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, August 2014, Elsevier

    Professor Trevor Lithgow

  86. Efficient construction of unmarked recombinant mycobacteria using an improved system

    Article • Journal of Microbiological Methods, August 2014, Elsevier

    Professor Trevor Lithgow

  87. A comprehensive analysis of the Omp85/TpsB protein superfamily structural diversity, taxonomic occurrence, and evolution

    Article • Frontiers in Microbiology, July 2014, Frontiers

    Professor Trevor Lithgow

  88. A mortise–tenon joint in the transmembrane domain modulates autotransporter assembly into bacterial outer membranes

    Article • Nature Communications, June 2014, Springer Science + Business Media

    Professor Anthony W Purcell, Dr Travis Beddoe, Professor Trevor Lithgow

  89. Emerging rules for effective antimicrobial coatings

    Article • Trends in Biotechnology, February 2014, Elsevier

    Professor Trevor Lithgow

  90. Transcriptional Activation of the mrkA Promoter of the Klebsiella pneumoniae Type 3 Fimbrial Operon by the c-di-GMP-Dependent MrkH Protein

    Article • PLOS One, November 2013, PLOS

    Professor Trevor Lithgow

  91. Modifications and Innovations in the Evolution of Mitochondrial Protein Import Pathways

    Article • October 2013, Springer Science + Business Media

    Professor Trevor Lithgow

  92. Structural insight into the biogenesis of β-barrel membrane proteins

    Article • Nature, September 2013, Nature

    Professor Trevor Lithgow

  93. Seaside transportation—from structure to function of translocation machines

    Article • EMBO Reports, June 2013, Wiley

    Professor Trevor Lithgow

  94. Self-assembly of ciprofloxacin and a tripeptide into an antimicrobial nanostructured hydrogel

    Article • Biomaterials, May 2013, Elsevier

    Dr Silvia Marchesan, Professor Trevor Lithgow

  95. Back to basics: A revealing secondary reduction of the mitochondrial protein import pathway in diverse intracellular parasites

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, February 2013, Elsevier

    Professor Trevor Lithgow

  96. Reconstitution of Membrane Proteins into Model Membranes: Seeking Better Ways to Retain Protein Activities

    Article • International Journal of Molecular Sciences, January 2013, MDPI AG

    Professor Trevor Lithgow

  97. Assembly of the Type II Secretion System such as Found in Vibrio cholerae Depends on the Novel Pilotin AspS

    Article • PLoS Pathogens, January 2013, PLOS

    Professor Anthony W Purcell, Professor Trevor Lithgow

  98. Nanomechanics measurements of live bacteria reveal a mechanism for bacterial cell protection: the polysaccharide capsule in Klebsiella is a responsive polymer hydrogel that adapts to osmotic stress

    Article • Soft Matter, January 2013, Royal Society of Chemistry

    Professor Trevor Lithgow

  99. Evolution of the β-barrel assembly machinery

    Article • Trends in Microbiology, December 2012, Elsevier

    Professor Trevor Lithgow

  100. A model system for mitochondrial biogenesis reveals evolutionary rewiring of protein import and membrane assembly pathways

    Article • Proceedings of the National Academy of Sciences, November 2012, Proceedings of the National Academy of Sciences

    Professor Trevor Lithgow

  101. Dynamic Association of BAM Complex Modules Includes Surface Exposure of the Lipoprotein BamC

    Article • Journal of Molecular Biology, September 2012, Elsevier

    Professor Trevor Lithgow

  102. A Bioinformatic Strategy for the Detection, Classification and Analysis of Bacterial Autotransporters

    Article • PLOS One, August 2012, PLOS

    Dr Rebecca Gorrell, Professor Trevor Lithgow

  103. An essential novel component of the noncanonical mitochondrial outer membrane protein import system of trypanosomatids

    Article • Molecular Biology of the Cell, July 2012, American Society for Cell Biology (ASCB)

    Professor Trevor Lithgow

  104. Response to Zarsky et al.

    Article • Current Biology, June 2012, Elsevier

    Professor Trevor Lithgow

  105. The evolution of new lipoprotein subunits of the bacterial outer membrane BAM complex

    Article • Molecular Microbiology, April 2012, Wiley

    Professor Trevor Lithgow

  106. Discovery of an archetypal protein transport system in bacterial outer membranes

    Article • Nature Structural & Molecular Biology, April 2012, Springer Science + Business Media

    Professor Mark A Schembri, Professor Anthony W Purcell, Professor Trevor Lithgow

  107. The Type II Secretion System and Its Ubiquitous Lipoprotein Substrate, SslE, Are Required for Biofilm Formation and Virulence of Enteropathogenic Escherichia coli

    Article • Infection and Immunity, March 2012, ASM Journals

    Associate Professor Cynthia B Whitchurch, Professor Trevor Lithgow

  108. Mitochondrial Sorting and Assembly Machinery Subunit Sam37 in Candida albicans: Insight into the Roles of Mitochondria in Fitness, Cell Wall Integrity, and Virulence

    Article • Eukaryotic Cell, January 2012, ASM Journals

    Professor Trevor Lithgow

  109. Legionella pneumophila Secretes a Mitochondrial Carrier Protein during Infection

    Article • PLoS Pathogens, January 2012, PLOS

    Professor Trevor Lithgow

  110. Targeting of Neisserial PorB to the mitochondrial outer membrane: an insight on the evolution of β-barrel protein assembly machines

    Article • Molecular Microbiology, October 2011, Wiley

    Professor Trevor Lithgow

  111. A Small Tim Homohexamer in the Relict Mitochondrion of Cryptosporidium

    Article • Molecular Biology and Evolution, October 2011, Oxford University Press (OUP)

    Professor Trevor Lithgow

  112. Mitochondrial Preprotein Translocase of Trypanosomatids Has a Bacterial Origin

    Article • Current Biology, October 2011, Elsevier

    Professor Trevor Lithgow

  113. The Core Components of Organelle Biogenesis and Membrane Transport in the Hydrogenosomes of Trichomonas vaginalis

    Article • PLOS One, September 2011, PLOS

    Professor Trevor Lithgow

  114. MrkH, a Novel c-di-GMP-Dependent Transcriptional Activator, Controls Klebsiella pneumoniae Biofilm Formation by Regulating Type 3 Fimbriae Expression

    Article • PLoS Pathogens, August 2011, PLOS

    Professor Mark A Schembri, Associate Professor Cynthia B Whitchurch, Professor Trevor Lithgow

  115. The mitochondrial import protein Mim1 promotes biogenesis of multispanning outer membrane proteins

    Article • Journal of Cell Biology, August 2011, Rockefeller University Press

    Professor Trevor Lithgow

  116. Minor modifications and major adaptations: The evolution of molecular machines driving mitochondrial protein import

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, March 2011, Elsevier

    Professor Trevor Lithgow

  117. The Minimal Proteome in the Reduced Mitochondrion of the Parasitic Protist Giardia intestinalis

    Article • PLOS One, February 2011, PLOS

    Professor Trevor Lithgow

  118. PUF proteins: repression, activation and mRNA localization

    Article • Trends in Cell Biology, February 2011, Elsevier

    Professor Trevor Lithgow

  119. Recognition of Mitochondrial Targeting Sequences by the Import Receptors Tom20 and Tom22

    Article • Journal of Molecular Biology, January 2011, Elsevier

    Associate Professor Paul R Gooley, Professor Trevor Lithgow

  120. Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2

    Article • Molecular Microbiology, December 2010, Wiley

    Professor Trevor Lithgow

  121. Ancestral and Derived Protein Import Pathways in the Mitochondrion of Reclinomonas americana

    Article • Molecular Biology and Evolution, November 2010, Oxford University Press (OUP)

    Professor Trevor Lithgow

  122. A Functional Tom70 in the Human Parasite Blastocystis sp.: Implications for the Evolution of the Mitochondrial Import Apparatus

    Article • Molecular Biology and Evolution, September 2010, Oxford University Press (OUP)

    Professor Trevor Lithgow, Anastasios D. Tsaousis

  123. Both the p33 and p55 Subunits of the Helicobacter pylori VacA Toxin Are Targeted to Mammalian Mitochondria

    Article • Journal of Molecular Biology, September 2010, Elsevier

    Professor Trevor Lithgow

  124. Mitochondrial Biogenesis: Sorting Mechanisms Cooperate in ABC Transporter Assembly

    Article • Current Biology, July 2010, Elsevier

    Professor Trevor Lithgow

  125. The Yeast PUF Protein Puf5 Has Pop2-Independent Roles in Response to DNA Replication Stress

    Article • PLOS One, May 2010, PLOS

    Professor Trevor Lithgow

  126. The Essentials of Protein Import in the Degenerate Mitochondrion of Entamoeba histolytica

    Article • PLoS Pathogens, March 2010, PLOS

    Professor Trevor Lithgow

  127. Tinkering Inside the Organelle

    Article • Science, February 2010, American Association for the Advancement of Science

    Professor Trevor Lithgow

  128. Evolution of macromolecular import pathways in mitochondria, hydrogenosomes and mitosomes

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, February 2010, Royal Society Publishing

    Professor Trevor Lithgow

  129. A Modular BAM Complex in the Outer Membrane of the α-Proteobacterium Caulobacter crescentus

    Article • PLOS One, January 2010, PLOS

    Professor Anthony W Purcell, Professor Trevor Lithgow

  130. Using Hidden Markov Models to Discover New Protein Transport Machines

    Article • January 2010, Springer Science + Business Media

    Professor Trevor Lithgow

  131. Systems Biology: The Next Frontier for Bioinformatics

    Article • Advances in Bioinformatics, January 2010, Hindawi Publishing Corporation

    Professor Trevor Lithgow

  132. Protein Secretion

    Article • January 2010, Springer Science + Business Media

    Professor Trevor Lithgow

  133. The reducible complexity of a mitochondrial molecular machine

    Article • Proceedings of the National Academy of Sciences, September 2009, Proceedings of the National Academy of Sciences

    Professor Trevor Lithgow

  134. Jid1 is a J-protein functioning in the mitochondrial matrix, unable to directly participate in endoplasmic reticulum associated protein degradation

    Article • FEBS Letters, August 2009, Wiley

    Professor Trevor Lithgow

  135. Importing Mitochondrial Proteins: Machineries and Mechanisms

    Article • Cell, August 2009, Elsevier

    Professor Trevor Lithgow

  136. Erratum to “Domain Organization of the Monomeric Form of the Tom70 Mitochondrial Import Receptor” [J. Mol. Biol. 388 (2009) 1043–1058]

    Article • Journal of Molecular Biology, July 2009, Elsevier

    Professor Trevor Lithgow

  137. The Protein Import Channel in the Outer Mitosomal Membrane of Giardia intestinalis

    Article • Molecular Biology and Evolution, June 2009, Oxford University Press (OUP)

    Professor Anthony W Purcell, Professor Trevor Lithgow

  138. Domain Organization of the Monomeric Form of the Tom70 Mitochondrial Import Receptor

    Article • Journal of Molecular Biology, May 2009, Elsevier

    Professor Trevor Lithgow

  139. The three domains of the mitochondrial outer membrane protein Mim1 have discrete functions in assembly of the TOM complex

    Article • FEBS Letters, April 2009, Wiley

    Professor Trevor Lithgow

  140. The Single Mitochondrial Porin of Trypanosoma brucei is the Main Metabolite Transporter in the Outer Mitochondrial Membrane

    Article • Molecular Biology and Evolution, December 2008, Oxford University Press (OUP)

    Professor Trevor Lithgow

  141. The Major Surface-Associated Saccharides of Klebsiella pneumoniae Contribute to Host Cell Association

    Article • PLOS One, November 2008, PLOS

    Professor Jerome F.L. Duval, Professor Trevor Lithgow

  142. Evidence of a Reduced and Modified Mitochondrial Protein Import Apparatus in Microsporidian Mitosomes

    Article • Eukaryotic Cell, November 2008, ASM Journals

    Professor Trevor Lithgow

  143. Protein secretion and outer membrane assembly in Alphaproteobacteria

    Article • FEMS Microbiology Reviews, November 2008, Oxford University Press (OUP)

    Professor Anthony W Purcell, Professor Trevor Lithgow

  144. Structure, topology and function of the translocase of the outer membrane of mitochondria

    Article • Plant Physiology and Biochemistry, March 2008, Elsevier

    Associate Professor Paul R Gooley, Professor Trevor Lithgow

  145. The Transmembrane Segment of Tom20 Is Recognized by Mim1 for Docking to the Mitochondrial TOM Complex

    Article • Journal of Molecular Biology, February 2008, Elsevier

    Associate Professor Paul R Gooley, Professor Trevor Lithgow

  146. Conserved substrate binding by chaperones in the bacterial periplasm and the mitochondrial intermembrane space

    Article • Biochemical Journal, January 2008, Portland Press Ltd.

    Professor Trevor Lithgow

  147. The direct route: a simplified pathway for protein import into the mitochondrion of trypanosomes

    Article • Trends in Cell Biology, January 2008, Elsevier

    Professor Trevor Lithgow

  148. The Twists and Turns of Maurer’s Cleft Trafficking in P. falciparum-Infected Erythrocytes

    Article • Traffic, December 2007, Wiley

    Professor Trevor Lithgow

  149. The Peripheral Membrane Subunits of the SAM Complex Function Codependently in Mitochondrial Outer Membrane Biogenesis

    Article • Molecular Biology of the Cell, October 2007, American Society for Cell Biology (ASCB)

    Professor Trevor Lithgow

  150. Re-assessing the locations of components of the classical vesicle-mediated trafficking machinery in transfected Plasmodium falciparum

    Article • International Journal for Parasitology, August 2007, Elsevier

    Professor Trevor Lithgow

  151. Domain Stealing by Receptors in a Protein Transport Complex

    Article • Molecular Biology and Evolution, June 2007, Oxford University Press (OUP)

    Professor Trevor Lithgow

  152. Conserved Motifs Reveal Details of Ancestry and Structure in the Small TIM Chaperones of the Mitochondrial Intermembrane Space

    Article • Molecular Biology and Evolution, February 2007, Oxford University Press (OUP)

    Professor Anthony W Purcell, Professor Trevor Lithgow

  153. TOM and SAM Machineries in Mitochondrial Protein Import and Outer Membrane Biogenesis

    Article • January 2007, Elsevier

    Professor Trevor Lithgow

  154. A mitochondrial protein affects cell morphology, mitochondrial segregation and virulence in Leishmania

    Article • International Journal for Parasitology, December 2006, Elsevier

    Professor Trevor Lithgow

  155. Microsporidian mitosomes retain elements of the general mitochondrial targeting system

    Article • Proceedings of the National Academy of Sciences, October 2006, Proceedings of the National Academy of Sciences

    Professor Trevor Lithgow

  156. Evolution of the Molecular Machines for Protein Import into Mitochondria

    Article • Science, July 2006, American Association for the Advancement of Science

    Professor Trevor Lithgow

  157. Human Bcl-2 cannot directly inhibit the Caenorhabditis elegans Apaf-1 homologue CED-4, but can interact with EGL-1

    Article • Journal of Cell Science, June 2006, The Company of Biologists

    Professor Trevor Lithgow

  158. The C-terminal TPR Domain of Tom70 Defines a Family of Mitochondrial Protein Import Receptors Found only in Animals and Fungi

    Article • Journal of Molecular Biology, May 2006, Elsevier

    Professor Trevor Lithgow

  159. Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae

    Article • European Journal of Biochemistry, April 2006, Wiley

    Professor Trevor Lithgow

  160. Convergent Evolution of Receptors for Protein Import into Mitochondria

    Article • Current Biology, February 2006, Elsevier

    Associate Professor Paul R Gooley, Professor Trevor Lithgow

  161. 1H, 13C and 15N Resonance Assignments of the Cytosolic Domain of Tom20 from Arabidopsis thaliana

    Article • Journal of Biomolecular NMR, November 2005, Springer Science + Business Media

    Associate Professor Paul R Gooley, Professor Trevor Lithgow

  162. Molecular architecture and function of the Omp85 family of proteins

    Article • Molecular Microbiology, October 2005, Wiley

    Professor Trevor Lithgow

  163. Giardia mitosomes and trichomonad hydrogenosomes share a common mode of protein targeting

    Article • Proceedings of the National Academy of Sciences, July 2005, Proceedings of the National Academy of Sciences

    Professor Trevor Lithgow

  164. Protein Targeting: Entropy, Energetics and Modular Machines

    Article • Current Biology, June 2005, Elsevier

    Professor Trevor Lithgow

  165. Mature DIABLO/Smac Is Produced by the IMP Protease Complex on the Mitochondrial Inner Membrane

    Article • Molecular Biology of the Cell, March 2005, American Society for Cell Biology (ASCB)

    Professor Trevor Lithgow

  166. Patterns that Define the Four Domains Conserved in Known and Novel Isoforms of the Protein Import Receptor Tom20

    Article • Journal of Molecular Biology, March 2005, Elsevier

    Associate Professor Paul R Gooley, Professor Trevor Lithgow

  167. Protein import into mitochondria: origins and functions today (Review)

    Article • Molecular Membrane Biology, January 2005, Taylor & Francis

    Professor Trevor Lithgow

  168. Mitochondrial Release of Pro-apoptotic Proteins

    Article • Journal of Biological Chemistry, November 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Trevor Lithgow

  169. Assembling the mitochondrial outer membrane

    Article • Nature Structural & Molecular Biology, November 2004, Nature

    Professor Trevor Lithgow

  170. Zim17, a Novel Zinc Finger Protein Essential for Protein Import into Mitochondria

    Article • Journal of Biological Chemistry, September 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Trevor Lithgow

  171. Distinct Roles for the Hsp40 and Hsp90 Molecular Chaperones during Cystic Fibrosis Transmembrane Conductance Regulator Degradation in Yeast

    Article • Molecular Biology of the Cell, September 2004, American Society for Cell Biology (ASCB)

    Professor Trevor Lithgow

  172. A Biophysical Analysis of the Tetratricopeptide Repeat-rich Mitochondrial Import Receptor, Tom70, Reveals an Elongated Monomer That Is Inherently Flexible, Unstable, and Unfolds via a Multistate Pathway

    Article • Journal of Biological Chemistry, August 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Trevor Lithgow

  173. The J-protein family: modulating protein assembly, disassembly and translocation

    Article • EMBO Reports, June 2004, Wiley

    Professor Trevor Lithgow

  174. Bacterial Proteins Predisposed for Targeting to Mitochondria

    Article • Molecular Biology and Evolution, April 2004, Oxford University Press (OUP)

    Professor Trevor Lithgow

  175. Tom22', an 8-kDa trans-Site Receptor in Plants and Protozoans, Is a Conserved Feature of the TOM Complex That Appeared Early in the Evolution of Eukaryotes

    Article • Molecular Biology and Evolution, February 2004, Oxford University Press (OUP)

    Professor Trevor Lithgow

  176. Protein hijacking

    Article • Cancer Cell, February 2004, Elsevier

    Professor Trevor Lithgow

  177. The Omp85 family of proteins is essential for outer membrane biogenesis in mitochondria and bacteria

    Article • Journal of Cell Biology, December 2003, Rockefeller University Press

    Professor Trevor Lithgow

  178. A Complete Set of SNAREs in Yeast

    Article • Traffic, November 2003, Wiley

    Professor Trevor Lithgow

  179. Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity

    Article • Journal of Cell Biology, September 2003, Rockefeller University Press

    Professor Trevor Lithgow

  180. A SNARE required for retrograde transport to the endoplasmic reticulum

    Article • Proceedings of the National Academy of Sciences, July 2003, Proceedings of the National Academy of Sciences

    Professor Trevor Lithgow

  181. Environmental stresses inhibit and stimulate different protein import pathways in plant mitochondria

    Article • FEBS Letters, June 2003, Wiley

    Professor Trevor Lithgow

  182. Tom40, the import channel of the mitochondrial outer membrane, plays an active role in sorting imported proteins

    Article • The EMBO Journal, May 2003, Wiley

    Professor Trevor Lithgow

  183. Bipartite Signals Mediate Subcellular Targeting of Tail-anchored Membrane Proteins inSaccharomyces cerevisiae

    Article • Journal of Biological Chemistry, January 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Trevor Lithgow

  184. Delivery of nascent polypeptides to the mitochondrial surface

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, September 2002, Elsevier

    Dr Travis Beddoe, Professor Trevor Lithgow

  185. The nascent polypeptide-associated complex (NAC) promotes interaction of ribosomes with the mitochondrial surface in vivo

    Article • FEBS Letters, March 2002, Wiley

    Dr Travis Beddoe, Professor Trevor Lithgow

  186. A conserved proline residue is present in the transmembrane-spanning domain of Tom7 and other tail-anchored protein subunits of the TOM translocase

    Article • FEBS Letters, March 2002, Wiley

    Professor Trevor Lithgow

  187. The mitochondrial protein targeting suppressor (mts1) mutation maps to the mRNA-binding domain of Npl3p and affects translation on cytoplasmic polysomes

    Article • Molecular Microbiology, January 2002, Wiley

    Dr Travis Beddoe, Professor Trevor Lithgow

  188. Article • Genome Biology, January 2002, Springer Science + Business Media

    Professor Trevor Lithgow

  189. RAC, a stable ribosome-associated complex in yeast formed by the DnaK-DnaJ homologs Ssz1p and zuotin

    Article • Proceedings of the National Academy of Sciences, March 2001, Proceedings of the National Academy of Sciences

    Professor Trevor Lithgow

  190. Targeting of C-Terminal (Tail)-Anchored Proteins: Understanding how Cytoplasmic Activities are Anchored to Intracellular Membranes

    Article • Traffic, January 2001, Wiley

    Professor Trevor Lithgow

  191. The alpha and the beta: protein translocation across mitochondrial and plastid outer membranes

    Article • Trends in Biochemical Sciences, January 2001, Elsevier

    Professor Trevor Lithgow

  192. A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae

    Article • The EMBO Journal, November 2000, Wiley

    Professor Trevor Lithgow

  193. How Do Plant Mitochondria Avoid Importing Chloroplast Proteins? Components of the Import Apparatus Tom20 and Tom22 from Arabidopsis Differ from Their Fungal Counterparts

    Article • PLANT PHYSIOLOGY, July 2000, American Society of Plant Biologists (ASPB)

    Professor Trevor Lithgow

  194. Targeting of proteins to mitochondria

    Article • FEBS Letters, June 2000, Wiley

    Professor Trevor Lithgow

  195. Mitochondrial FtsZ in a Chromophyte Alga

    Article • Science, February 2000, American Association for the Advancement of Science

    Professor Trevor Lithgow

  196. A First Glimpse at the Structure of the Tom Translocase from the Mitochondrial Outer Membrane: Figure 1

    Article • Journal of Cell Biology, November 1999, Rockefeller University Press

    Professor Trevor Lithgow

  197. Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division

    Article • Proceedings of the National Academy of Sciences, August 1999, Proceedings of the National Academy of Sciences

    Professor Trevor Lithgow

  198. Targeting of tail-anchored proteins to yeast mitochondria in vivo

    Article • FEBS Letters, May 1999, Wiley

    Professor Trevor Lithgow

  199. The Tom channel in the mitochondrial outer membrane: alive and kicking

    Article • BioEssays, April 1999, Wiley

    Professor Trevor Lithgow

  200. A Toxic Fusion Protein Accumulating between the Mitochondrial Membranes Inhibits Protein Assemblyin Vivo

    Article • Journal of Biological Chemistry, December 1998, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Trevor Lithgow

  201. The yeast nascent polypeptide-associated complex initiates protein targeting to mitochondria in vivo

    Article • Proceedings of the National Academy of Sciences, March 1998, Proceedings of the National Academy of Sciences

    Professor Trevor Lithgow

  202. A reply to Preiss et al.

    Article • Trends in Biochemical Sciences, August 1997, Elsevier

    Professor Trevor Lithgow

  203. The protein encoded by the MFT1 gene is a targeting factor for mitochondrial precursor proteins, and not a core ribosomal protein

    Article • FEBS Letters, April 1997, Wiley

    Dr Travis Beddoe, Professor Trevor Lithgow

  204. Highways for protein delivery to the mitochondria

    Article • Trends in Biochemical Sciences, April 1997, Elsevier

    Professor Trevor Lithgow

  205. Mft52, an Acid-bristle Protein in the Cytosol That Delivers Precursor Proteins to Yeast Mitochondria

    Article • Journal of Biological Chemistry, February 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Trevor Lithgow

  206. Article • Journal of Bioenergetics and Biomembranes, January 1997, Springer Science + Business Media

    Professor Trevor Lithgow

  207. Reconstitution of the initial steps of mitochondrial protein import

    Article • Nature, August 1995, Nature

    Professor Trevor Lithgow

  208. Import of the Cytochrome Oxidase Subunit Va Precursor into Yeast Mitochondria Is Mediated by the Outer Membrane Receptor Mas20p

    Article • Journal of Biological Chemistry, June 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Trevor Lithgow

  209. Mas37p, a novel receptor subunit for protein import into mitochondria

    Article • Journal of Cell Biology, April 1995, Rockefeller University Press

    Professor Trevor Lithgow

  210. The Yeast Mitochondrial Protein Import Receptor Mas20p Binds Precursor Proteins through Electrostatic Interaction with the Positively Charged Presequence

    Article • Journal of Biological Chemistry, March 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Trevor Lithgow

  211. The protein import receptor of mitochondria

    Article • Trends in Biochemical Sciences, March 1995, Elsevier

    Professor Trevor Lithgow

  212. Import and Folding of Proteins by Mitochondria

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 1995, Cold Spring Harbor Laboratory Press

    Professor Trevor Lithgow

  213. The mitochondrial outer membrane protein Mas22p is essential for protein import and viability of yeast.

    Article • Proceedings of the National Academy of Sciences, December 1994, Proceedings of the National Academy of Sciences

    Professor Trevor Lithgow

  214. An escherichia coli gene showing a potential ancestral relationship to the genes for the mitochondrial import site proteins ISP42 and MOM38

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, December 1993, Elsevier

    Professor Trevor Lithgow

  215. A constitutive form of heat-shock protein 70 is located in the outer membranes of mitochondria from rat liver

    Article • FEBS Letters, October 1993, Wiley

    Professor Trevor Lithgow

  216. Do cytosolic factors prevent promiscuity at the membrane surface?

    Article • FEBS Letters, August 1993, Wiley

    Professor Trevor Lithgow

  217. Prechaperonin 60 and preornithine transcarbamylase share componunts of the import apparatus but have distinct maturation pathways in rat liver mitochondria

    Article • European Journal of Biochemistry, February 1993, Wiley

    Professor Trevor Lithgow

  218. Identification of a GTP-binding protein in the contact sites between inner and outer mitochondrial membranes

    Article • Biochemical and Biophysical Research Communications, November 1991, Elsevier

    Professor Trevor Lithgow

  219. High-Level Expression of a Mitochondrial Enzyme, Ornithine Transcarbamylase from Rat Liver, in a Baculovirus Expression System

    Article • DNA and Cell Biology, July 1991, Mary Ann Liebert Inc

    Professor Trevor Lithgow

  220. Primary structure of mammalian ribosomal protein S6

    Article • Biochemistry, January 1988, American Chemical Society (ACS)

    Professor Trevor Lithgow

  221. Pharmaco-ontogeny of reward: Enhancement of self-stimulation by d-amphetamine and cocaine in 3- and 10-day-old rats

    Article • Developmental Brain Research, January 1986, Elsevier

    Gordon A. Barr, Professor Trevor Lithgow

  222. Effect of age on benzodiazepine-induced behavioural convulsions in rats

    Article • Nature, March 1983, Nature

    Professor Trevor Lithgow

  223. A method for stereotaxic implantation in neonatal rats

    Article • Developmental Brain Research, September 1981, Elsevier

    Professor Trevor Lithgow, Gordon A. Barr