All Stories

  1. A Ras-like GTPase in African trypanosomes

    Article • March 2025, Cold Spring Harbor Laboratory Press

    Prof Mark C Field

  2. A lineage-specific protein network at the trypanosome nuclear envelope

    Article • Nucleus, April 2024, Taylor & Francis

    Prof Mark C Field

  3. Deviating from the norm: Nuclear organisation in trypanosomes

    Article • Current Opinion in Cell Biology, December 2023, Elsevier

    Prof Mark C Field

  4. Trypanosomes as a magnifying glass for cell and molecular biology

    Article • Trends in Parasitology, November 2023, Elsevier

    Dr Dave Speijer, Prof Mark C Field

  5. Evolutionary, structural and functional insights in nuclear organisation and nucleocytoplasmic transport in trypanosomes

    Article • FEBS Letters, October 2023, Wiley

    Prof Mark C Field

  6. Extracellular vesicles secreted by Echinococcus multilocularis: important players in angiogenesis promotion

    Article • Microbes and Infection, September 2023, Elsevier

    Prof Mark C Field

  7. Evolution of cullin E3 ubiquitin ligases and function in trypanosomes

    Article • July 2023, Cold Spring Harbor Laboratory Press

    Prof Mark C Field

  8. Identification of inhibitors for the transmembrane Trypanosoma cruzi eIF2α kinase relevant for parasite proliferation

    Article • Journal of Biological Chemistry, July 2023, Elsevier

    Prof Mark C Field

  9. Lessons from the deep: mechanisms behind diversification of eukaryotic protein complexes

    Article • Biological Reviews, June 2023, Wiley

    Dr Dave Speijer, Prof Mark C Field

  10. Functional differentiation of Sec13 paralogues in the euglenozoan protists

    Article • Open Biology, June 2023, Royal Society Publishing

    Prof Mark C Field

  11. Trypanosoma cruziVDU deubiquitinase mediates surface protein trafficking and infectivity

    Article • April 2023, Cold Spring Harbor Laboratory Press

    Prof Mark C Field

  12. Functional differentiation of Sec13 paralogs in the euglenozoan protists

    Article • November 2022, Cold Spring Harbor Laboratory Press

    Prof Mark C Field

  13. Sending the message: specialized RNA export mechanisms in trypanosomes

    Article • Trends in Parasitology, October 2022, Elsevier

    Prof Mark C Field

  14. Microbe Profile: Euglena gracilis: photogenic, flexible and hardy

    Article • Microbiology, September 2022, Society for General Microbiology

    Prof Mark C Field

  15. Correction to: Evolution of factors shaping the endoplasmic reticulum

    Article • Traffic, September 2022, Wiley

    Prof Mark C Field

  16. African trypanosome strategies for conquering new hosts and territories: the end of monophyly?

    Article • Trends in Parasitology, September 2022, Elsevier

    Prof Mark C Field

  17. Evolution of factors shaping the endoplasmic reticulum

    Article • Traffic, August 2022, Wiley

    Prof Mark C Field

  18. A novel membrane complex is required for docking and regulated exocytosis of lysosome-related organelles in Tetrahymena thermophila

    Article • PLoS Genetics, May 2022, PLOS

    Professor Aaron P Turkewitz, Prof Mark C Field

  19. Proteomics Uncovers Novel Components of an Interactive Protein Network Supporting RNA Export in Trypanosomes

    Article • Molecular & Cellular Proteomics, March 2022, Elsevier

    Prof Mark C Field

  20. The distinctive flagellar proteome of Euglena gracilis illuminates the complexities of protistan flagella adaptation

    Article • New Phytologist, August 2021, Wiley

    Prof Mark C Field

  21. Evolution and diversification of the nuclear pore complex

    Article • Biochemical Society Transactions, July 2021, Portland Press Ltd.

    Prof Mark C Field

  22. A hub-and-spoke nuclear lamina architecture in trypanosomes

    Article • Journal of Cell Science, June 2021, The Company of Biologists

    Prof Mark C Field

  23. Kinetoplastid cell biology and genetics, from the 2020 British Society for Parasitology Trypanosomiasis and Leishmaniasis symposium, Granada, Spain

    Article • Parasitology, June 2021, Cambridge University Press

    Prof Mark C Field

  24. Evolving Differentiation in African Trypanosomes

    Article • Trends in Parasitology, April 2021, Elsevier

    Prof Mark C Field

  25. Evolution, function and roles in drug sensitivity of trypanosome aquaglyceroporins

    Article • Parasitology, February 2021, Cambridge University Press

    Prof Mark C Field

  26. Evolution and diversification of the nuclear envelope

    Article • Nucleus, January 2021, Taylor & Francis

    Prof Mark C Field

  27. The endosomal TbTpr86/TbUsp7/SkpZ (TUS) complex controls surface protein abundance in trypanosomes

    Article • November 2020, Cold Spring Harbor Laboratory Press

    Prof Mark C Field

  28. EIF2αphosphorylation is regulated in intracellular amastigotes for the generation of infectiveTrypanosoma cruzitrypomastigote forms

    Article • Cellular Microbiology, July 2020, Wiley

    Prof Mark C Field

  29. Instability of aquaglyceroporin (AQP) 2 contributes to drug resistance in Trypanosoma brucei

    Article • PLoS Neglected Tropical Diseases, July 2020, PLOS

    Prof Mark C Field

  30. A Uniquely Complex Mitochondrial Proteome from Euglena gracilis

    Article • Molecular Biology and Evolution, April 2020, Oxford University Press (OUP)

    Prof Mark C Field

  31. Evolution of late steps in exocytosis: conservation and specialization of the exocyst complex

    Article • Wellcome Open Research, November 2019, Faculty of 1000, Ltd.

    Prof Mark C Field

  32. Evolution of late steps in exocytosis: conservation, specialization

    Article • Wellcome Open Research, July 2019, Faculty of 1000, Ltd.

    Prof Mark C Field

  33. Monoallelic expression and epigenetic inheritance sustained by a Trypanosoma brucei variant surface glycoprotein exclusion complex

    Article • Nature Communications, July 2019, Springer Science + Business Media

    Prof Mark C Field

  34. Pore timing: the evolutionary origins of the nucleus and nuclear pore complex

    Article • F1000Research, April 2019, Faculty of 1000, Ltd.

    Prof Mark C Field

  35. Evolution of protein trafficking in kinetoplastid parasites: Complexity and pathogenesis

    Article • Traffic, July 2018, Wiley

    Prof Mark C Field

  36. Adaptation and Therapeutic Exploitation of the Plasma Membrane of African Trypanosomes

    Article • Genes, July 2018, MDPI AG

    Prof Mark C Field

  37. Adaptation and Therapeutic Exploitation of the Plasma Membrane of African Trypanosomes

    Article • June 2018, MDPI AG

    Prof Mark C Field

  38. Regulation of early endosomes across eukaryotes: Evolution and functional homology of Vps9 proteins

    Article • Traffic, April 2018, Wiley

    Prof Mark C Field

  39. Unlocking the biological potential ofEuglena gracilis: evolution, cell biology and significance to parasitism

    Article • December 2017, Cold Spring Harbor Laboratory Press

    Prof Mark C Field

  40. Comparative interactomics provides evidence for functional specialization of the nuclear pore complex

    Article • Nucleus, May 2017, Taylor & Francis

    Prof Mark C Field

  41. Evolution of the endomembrane systems of trypanosomatids – conservation and specialisation

    Article • Journal of Cell Science, April 2017, The Company of Biologists

    Prof Mark C Field

  42. Lineage-specific proteins essential for endocytosis in trypanosomes

    Article • Journal of Cell Science, April 2017, The Company of Biologists

    Prof Mark C Field

  43. A leucine aminopeptidase is involved in kinetoplast DNA segregation in Trypanosoma brucei

    Article • PLoS Pathogens, April 2017, PLOS

    Prof Mark C Field

  44. Specialising the parasite nucleus: Pores, lamins, chromatin, and diversity

    Article • PLoS Pathogens, March 2017, PLOS

    Prof Mark C Field

  45. The Trypanosome Exocyst: A Conserved Structure Revealing a New Role in Endocytosis

    Article • PLoS Pathogens, January 2017, PLOS

    Dr Mary Munson, Prof Mark C Field

  46. Exploiting the Achilles’ heel of membrane trafficking in trypanosomes

    Article • Current Opinion in Microbiology, December 2016, Elsevier

    Prof Mark C Field

  47. The changing view of eukaryogenesis – fossils, cells, lineages and how they all come together

    Article • Journal of Cell Science, September 2016, The Company of Biologists

    Dr Laura Eme, Prof Mark C Field

  48. Co-dependence between trypanosome nuclear lamina components in nuclear stability and control of gene expression

    Article • Nucleic Acids Research, September 2016, Oxford University Press (OUP)

    Prof Mark C Field

  49. Making the pathogen: Evolution and adaptation in parasitic protists

    Article • Molecular and Biochemical Parasitology, September 2016, Elsevier

    Prof Mark C Field

  50. Resolving the homology—function relationship through comparative genomics of membrane-trafficking machinery and parasite cell biology

    Article • Molecular and Biochemical Parasitology, September 2016, Elsevier

    Prof Mark C Field

  51. Conservation and divergence within the clathrin interactome of Trypanosoma cruzi

    Article • Scientific Reports, August 2016, Springer Science + Business Media

    Prof Mark C Field

  52. Ancient Eukaryotic Origin and Evolutionary Plasticity of Nuclear Lamina

    Article • Genome Biology and Evolution, April 2016, Oxford University Press (OUP)

    Prof Mark C Field

  53. Genome of Leptomonas pyrrhocoris: a high-quality reference for monoxenous trypanosomatids and new insights into evolution of Leishmania

    Article • Scientific Reports, March 2016, Nature

    Professor Fred R. Opperdoes, Prof Mark C Field

  54. Interactome Mapping Reveals the Evolutionary History of the Nuclear Pore Complex

    Article • PLoS Biology, February 2016, PLOS

    Prof Mark C Field

  55. Kinetoplastid Phylogenomics Reveals the Evolutionary Innovations Associated with the Origins of Parasitism

    Article • Current Biology, January 2016, Elsevier

    Prof Mark C Field

  56. Subunit connectivity, assembly determinants and architecture of the yeast exocyst complex

    Article • Nature Structural & Molecular Biology, December 2015, Nature

    Dr Mary Munson, Prof Mark C Field

  57. Correction: Modulation of the Surface Proteome through Multiple Ubiquitylation Pathways in African Trypanosomes

    Article • PLoS Pathogens, November 2015, PLOS

    Prof Mark C Field

  58. Phosphoinositides, kinases and adaptors coordinating endocytosis in Trypanosoma brucei

    Article • Communicative & Integrative Biology, November 2015, Taylor & Francis

    Prof Mark C Field

  59. Modulation of the Surface Proteome through Multiple Ubiquitylation Pathways in African Trypanosomes

    Article • PLoS Pathogens, October 2015, PLOS

    Prof Mark C Field

  60. Quantitative sequencing confirms VSG diversity as central to immune evasion by Trypanosoma brucei

    Article • Trends in Parasitology, August 2015, Elsevier

    Prof Mark C Field

  61. Architecture of a Host–Parasite Interface: Complex Targeting Mechanisms Revealed Through Proteomics

    Article • Molecular & Cellular Proteomics, July 2015, Elsevier

    Prof Mark C Field

  62. Localization of serum resistance-associated protein inTrypanosoma brucei rhodesienseand transgenicTrypanosoma brucei brucei

    Article • Cellular Microbiology, June 2015, Wiley

    Prof Mark C Field

  63. ENTH and ANTH domain proteins participate in AP2-independent clathrin-mediated endocytosis

    Article • Journal of Cell Science, June 2015, The Company of Biologists

    Prof Mark C Field

  64. Evolutionary cell biology: Two origins, one objective

    Article • Proceedings of the National Academy of Sciences, November 2014, Proceedings of the National Academy of Sciences

    Prof Mark C Field

  65. The mitochondrial respiratory chain of the secondary green alga Euglena gracilis shares many additional subunits with parasitic Trypanosomatidae

    Article • Mitochondrion, November 2014, Elsevier

    Prof Mark C Field

  66. An extensive endoplasmic reticulum-localised glycoprotein family in trypanosomatids

    Article • Microbial Cell, October 2014, Shared Science Publishers OG

    Prof Mark C Field

  67. Missing Pieces of an Ancient Puzzle: Evolution of the Eukaryotic Membrane-Trafficking System

    Article • Cold Spring Harbor Perspectives in Biology, October 2014, Cold Spring Harbor Laboratory Press

    Prof Mark C Field

  68. A draft genome for the African crocodilian trypanosome Trypanosoma grayi

    Article • Scientific Data, August 2014, Springer Science + Business Media

    Prof Mark C Field

  69. Touching from a distance

    Article • Nucleus, July 2014, Taylor & Francis

    Prof Mark C Field

  70. Evolution of the nucleus

    Article • Current Opinion in Cell Biology, June 2014, Elsevier

    Prof Mark C Field

  71. Life and times: synthesis, trafficking, and evolution of VSG

    Article • Trends in Parasitology, May 2014, Elsevier

    Prof Mark C Field

  72. Nuclear pore complex evolution: a trypanosome Mlp analogue functions in chromosomal segregation but lacks transcriptional barrier activity

    Article • Molecular Biology of the Cell, May 2014, American Society for Cell Biology (ASCB)

    Prof Mark C Field

  73. A comparative analysis of trypanosomatid SNARE proteins

    Article • Parasitology International, April 2014, Elsevier

    Prof Mark C Field

  74. The Streamlined Genome of Phytomonas spp. Relative to Human Pathogenic Kinetoplastids Reveals a Parasite Tailored for Plants

    Article • PLoS Genetics, February 2014, PLOS

    Professor Roberto Docampo, Professor Fred R. Opperdoes, Prof Mark C Field

  75. The Cell Biology of the Endocytic System from an Evolutionary Perspective

    Article • Cold Spring Harbor Perspectives in Biology, January 2014, Cold Spring Harbor Laboratory Press

    Prof Mark C Field

  76. Enriching the Pore: Splendid Complexity from Humble Origins

    Article • Traffic, January 2014, Wiley

    Prof Mark C Field

  77. The Ancient Small GTPase Rab21 Functions in Intermediate Endocytic Steps in Trypanosomes

    Article • Eukaryotic Cell, December 2013, ASM Journals

    Prof Mark C Field

  78. Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context inVSGexpression control

    Article • Cellular Microbiology, October 2013, Wiley

    Prof Mark C Field

  79. Molecular paleontology and complexity in the last eukaryotic common ancestor

    Article • Critical Reviews in Biochemistry and Molecular Biology, July 2013, Taylor & Francis

    Prof Mark C Field

  80. Cell density-dependent ectopic expression in bloodstream form Trypanosoma brucei

    Article • Experimental Parasitology, June 2013, Elsevier

    Prof Mark C Field

  81. Receptor-mediated endocytosis for drug delivery in African trypanosomes: fulfilling Paul Ehrlich's vision of chemotherapy

    Article • Trends in Parasitology, May 2013, Elsevier

    Prof Mark C Field

  82. Evolution of modular intraflagellar transport from a coatomer-like progenitor

    Article • Proceedings of the National Academy of Sciences, April 2013, Proceedings of the National Academy of Sciences

    Prof Mark C Field

  83. Adaptin evolution in kinetoplastids and emergence of the variant surface glycoprotein coat in African trypanosomatids

    Article • Molecular Phylogenetics and Evolution, April 2013, Elsevier

    Prof Mark C Field

  84. A Cell-surface Phylome for African Trypanosomes

    Article • PLoS Neglected Tropical Diseases, March 2013, PLOS

    Prof Mark C Field

  85. Evolution of Tre-2/Bub2/Cdc16 (TBC) Rab GTPase-activating proteins

    Article • Molecular Biology of the Cell, March 2013, American Society for Cell Biology (ASCB)

    Prof Mark C Field

  86. TbFRP, a novel FYVE-domain containing phosphoinositide-binding Ras-like GTPase from trypanosomes

    Article • Experimental Parasitology, March 2013, Elsevier

    Prof Mark C Field

  87. Proteomic Analysis of Clathrin Interactions in Trypanosomes Reveals Dynamic Evolution of Endocytosis

    Article • Traffic, February 2013, Wiley

    Prof Mark C Field

  88. Differential Localization of the Two T. brucei Poly(A) Binding Proteins to the Nucleus and RNP Granules Suggests Binding to Distinct mRNA Pools

    Article • PLOS One, January 2013, PLOS

    Prof Mark C Field

  89. An automated graphics tool for comparative genomics: the Coulson plot generator

    Article • BMC Bioinformatics, January 2013, Springer Science + Business Media

    Prof Mark C Field

  90. Evidence for Recycling of Invariant Surface Transmembrane Domain Proteins in African Trypanosomes

    Article • Eukaryotic Cell, December 2012, ASM Journals

    Prof Mark C Field

  91. Pyrimidine Salvage in Trypanosoma brucei Bloodstream Forms and the Trypanocidal Action of Halogenated Pyrimidines

    Article • Molecular Pharmacology, November 2012, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Prof Mark C Field

  92. Telomeres, tethers and trypanosomes

    Article • Nucleus, November 2012, Taylor & Francis

    Prof Mark C Field

  93. RAB-Like 2 Has an Essential Role in Male Fertility, Sperm Intra-Flagellar Transport, and Tail Assembly

    Article • PLoS Genetics, October 2012, PLOS

    Prof Mark C Field

  94. Epigenetic mechanisms, nuclear architecture and the control of gene expression in trypanosomes

    Article • Expert Reviews in Molecular Medicine, May 2012, Cambridge University Press

    Prof Mark C Field

  95. Terminal galactosylation of glycoconjugates in Plasmodium falciparum asexual blood stages and Trypanosoma brucei bloodstream trypomastigotes

    Article • Experimental Parasitology, April 2012, Elsevier

    Prof Mark C Field

  96. NUP-1 Is a Large Coiled-Coil Nucleoskeletal Protein in Trypanosomes with Lamin-Like Functions

    Article • PLoS Biology, March 2012, PLOS

    Prof Mark C Field

  97. Sculpting the endomembrane system in deep time: high resolution phylogenetics of Rab GTPases

    Article • Journal of Cell Science, February 2012, The Company of Biologists

    Prof Mark C Field

  98. Antigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species

    Article • Proceedings of the National Academy of Sciences, February 2012, Proceedings of the National Academy of Sciences

    Prof Mark C Field

  99. Proteomics on the rims: insights into the biology of the nuclear envelope and flagellar pocket of trypanosomes

    Article • Parasitology, February 2012, Cambridge University Press

    Prof Mark C Field

  100. High-throughput decoding of antitrypanosomal drug efficacy and resistance

    Article • Nature, January 2012, Springer Science + Business Media

    Prof Mark C Field

  101. Rab28 function in trypanosomes: interactions with retromer and ESCRT pathways

    Article • Journal of Cell Science, November 2011, The Company of Biologists

    Prof Mark C Field

  102. A Novel Rho-Like Protein TbRHP Is Involved in Spindle Formation and Mitosis in Trypanosomes

    Article • PLOS One, November 2011, PLOS

    Prof Mark C Field

  103. Specializations in a successful parasite: What makes the bloodstream-form African trypanosome so deadly?

    Article • Molecular and Biochemical Parasitology, October 2011, Elsevier

    Prof Mark C Field

  104. High Affinity Nanobodies against the Trypanosome brucei VSG Are Potent Trypanolytic Agents that Block Endocytosis

    Article • PLoS Pathogens, June 2011, PLOS

    Prof Mark C Field, Prof. Dr. ir. Benoit Stijlemans

  105. On a bender—BARs, ESCRTs, COPs, and finally getting your coat

    Article • Journal of Cell Biology, June 2011, Rockefeller University Press

    Prof Mark C Field

  106. Rab11 Function in Trypanosoma brucei: Identification of Conserved and Novel Interaction Partners

    Article • Eukaryotic Cell, June 2011, ASM Journals

    Prof Mark C Field

  107. Ubiquitylation and Developmental Regulation of Invariant Surface Protein Expression in Trypanosomes

    Article • Eukaryotic Cell, May 2011, ASM Journals

    Prof Mark C Field

  108. Evolution of the Karyopherin-β Family of Nucleocytoplasmic Transport Factors; Ancient Origins and Continued Specialization

    Article • PLOS One, April 2011, PLOS

    Prof Mark C Field

  109. Evolutionary reconstruction of the retromer complex and its function in Trypanosoma brucei

    Article • Journal of Cell Science, April 2011, The Company of Biologists

    Prof Mark C Field

  110. Trypanosoma brucei brucei: Endocytic recycling is important for mouse infectivity

    Article • Experimental Parasitology, April 2011, Elsevier

    Prof Mark C Field

  111. A Conserved Coatomer-related Complex Containing Sec13 and Seh1 Dynamically Associates With the Vacuole in Saccharomyces cerevisiae

    Article • Molecular & Cellular Proteomics, March 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Mark C Field

  112. Rab23 is a flagellar protein in Trypanosoma brucei

    Article • BMC Research Notes, January 2011, Springer Science + Business Media

    Prof Mark C Field

  113. Regulation of Thromboxane Receptor Signaling at Multiple Levels by Oxidative Stress-Induced Stabilization, Relocation and Enhanced Responsiveness

    Article • PLOS One, September 2010, PLOS

    Prof Mark C Field

  114. Trypanosoma brucei: Trypanosome-specific endoplasmic reticulum proteins involved in variant surface glycoprotein expression

    Article • Experimental Parasitology, July 2010, Elsevier

    Prof Mark C Field

  115. Rab protein evolution and the history of the eukaryotic endomembrane system

    Article • Cellular and Molecular Life Sciences, June 2010, Springer Science + Business Media

    Prof Mark C Field

  116. The Genome of Naegleria gruberi Illuminates Early Eukaryotic Versatility

    Article • Cell, March 2010, Elsevier

    Prof Mark C Field

  117. Chaperone Requirements for Biosynthesis of the Trypanosome Variant Surface Glycoprotein

    Article • PLOS One, January 2010, PLOS

    Prof Mark C Field

  118. Evidence that low endocytic activity is not directly responsible for human serum resistance in the insect form of African trypanosomes

    Article • BMC Research Notes, January 2010, Springer Science + Business Media

    Prof Mark C Field

  119. The trypanosome flagellar pocket

    Article • Nature Reviews Microbiology, October 2009, Nature

    Prof Mark C Field

  120. The Trypanosome Rab-Related Proteins RabX1 and RabX2 Play No Role in IntraCellular Trafficking but May Be Involved in Fly Infectivity

    Article • PLOS One, September 2009, PLOS

    Prof Mark C Field

  121. Evidence for a Shared Nuclear Pore Complex Architecture That Is Conserved from the Last Common Eukaryotic Ancestor

    Article • Molecular & Cellular Proteomics, June 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Mark C Field

  122. Drug screening by crossing membranes: a novel approach to identification of trypanocides

    Article • Biochemical Journal, April 2009, Portland Press Ltd.

    Prof Mark C Field

  123. The Single ENTH-Domain Protein of Trypanosomes; Endocytic Functions and Evolutionary Relationship with Epsin

    Article • Traffic, March 2009, Wiley

    Prof Mark C Field

  124. First and last ancestors: reconstructing evolution of the endomembrane system with ESCRTs, vesicle coat proteins, and nuclear pore complexes

    Article • Current Opinion in Cell Biology, February 2009, Elsevier

    Prof Mark C Field

  125. Evolution of specificity in the eukaryotic endomembrane system

    Article • The International Journal of Biochemistry & Cell Biology, February 2009, Elsevier

    Prof Mark C Field

  126. Chapter 1 Macromolecular Trafficking and Immune Evasion in African Trypanosomes

    Article • January 2009, Elsevier

    Prof Mark C Field

  127. Ubiquitylation is Required for Degradation of Transmembrane Surface Proteins in Trypanosomes

    Article • Traffic, October 2008, Wiley

    Prof Mark C Field

  128. Evolution of the Multivesicular Body ESCRT Machinery; Retention Across the Eukaryotic Lineage

    Article • Traffic, October 2008, Wiley

    Prof Mark C Field

  129. Implications of the new eukaryotic systematics for parasitologists

    Article • Parasitology International, June 2008, Elsevier

    Prof Mark C Field

  130. How complex is GTPase signaling in trypanosomes?

    Article • Trends in Parasitology, June 2008, Elsevier

    Prof Mark C Field

  131. Phylogeny of endocytic components yields insight into the process of nonendosymbiotic organelle evolution

    Article • Proceedings of the National Academy of Sciences, January 2008, Proceedings of the National Academy of Sciences

    Prof Mark C Field

  132. The trypanosome transcriptome is remodelled during differentiation but displays limited responsiveness within life stages

    Article • BMC Genomics, January 2008, Springer Science + Business Media

    Prof Mark C Field

  133. Analysis of Small GTPase Function in Trypanosomes

    Article • January 2008, Elsevier

    Prof Mark C Field

  134. Dileucine signal-dependent and AP-1-independent targeting of a lysosomal glycoprotein in Trypanosoma brucei

    Article • Molecular and Biochemical Parasitology, December 2007, Elsevier

    Prof Mark C Field

  135. Activation of Endocytosis as an Adaptation to the Mammalian Host by Trypanosomes

    Article • Eukaryotic Cell, September 2007, ASM Journals

    Prof Mark C Field

  136. Evolution of the eukaryotic membrane-trafficking system: origin, tempo and mode

    Article • Journal of Cell Science, August 2007, The Company of Biologists

    Prof Mark C Field

  137. Intracellular Trafficking in the Trypanosomatids

    Article • Traffic, April 2007, Wiley

    Prof Mark C Field

  138. Article • BMC Evolutionary Biology, January 2007, Springer Science + Business Media

    Prof Mark C Field

  139. Chromosome-Wide Analysis of Gene Function by RNA Interference in the African Trypanosome

    Article • Eukaryotic Cell, September 2006, ASM Journals

    Prof Mark C Field

  140. TbVps34, the Trypanosome Orthologue of Vps34, Is Required for Golgi Complex Segregation

    Article • Journal of Biological Chemistry, July 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Mark C Field, Belinda Hall

  141. Dramatic reorganisation of Trichomonas endomembranes during amoebal transformation: A possible role for G-proteins☆

    Article • Molecular and Biochemical Parasitology, July 2006, Elsevier

    Prof Mark C Field

  142. Electrical and optical performance of InAs/GaSb superlattice LWIR detectors

    Article • February 2006, SPIE

    Prof Mark C Field

  143. Trypanosoma brucei: TbRAB4 regulates membrane recycling and expression of surface proteins in procyclic forms

    Article • Experimental Parasitology, November 2005, Elsevier

    Prof Mark C Field, Belinda Hall

  144. Signalling the genome: the Ras-like small GTPase family of trypanosomatids

    Article • Trends in Parasitology, October 2005, Elsevier

    Prof Mark C Field

  145. Identification of a very large Rab GTPase family in the parasitic protozoan Trichomonas vaginalis

    Article • Molecular and Biochemical Parasitology, October 2005, Elsevier

    Prof Mark C Field

  146. ER-associated protein degradation is a common mechanism underpinning numerous monogenic diseases including Robinow syndrome

    Article • Human Molecular Genetics, July 2005, Oxford University Press (OUP)

    Prof Mark C Field

  147. The Genome of the African Trypanosome Trypanosoma brucei

    Article • Science, July 2005, American Association for the Advancement of Science

    Professor Elodie Ghedin, Prof Mark C Field, Professor Fred R. Opperdoes

  148. An Evolutionarily Conserved Coiled-Coil Protein Implicated in Polycystic Kidney Disease Is Involved in Basal Body Duplication and Flagellar Biogenesis in Trypanosoma brucei

    Article • Molecular and Cellular Biology, May 2005, ASM Journals

    Prof Mark C Field

  149. Developmental Variation in Rab11-Dependent Trafficking in Trypanosoma brucei

    Article • Eukaryotic Cell, May 2005, ASM Journals

    Prof Mark C Field, Belinda Hall

  150. A bioinformatic analysis of the RAB genes of Trypanosoma brucei

    Article • Molecular and Biochemical Parasitology, May 2005, Elsevier

    Prof Mark C Field

  151. The role of alternative splicing and C-terminal amino acids in thromboxane receptor stabilization

    Article • Biochemical and Biophysical Research Communications, April 2005, Elsevier

    Prof Mark C Field

  152. Perturbation of local endogenous expression by insertion of Pol I expression constructs into the genome of Trypanosoma brucei

    Article • Experimental Parasitology, March 2005, Elsevier

    Prof Mark C Field

  153. Reconstitution of glycopeptide export in mixed detergent-solubilised and resealed microsomes depleted of lumenal components

    Article • Journal of Biochemical and Biophysical Methods, January 2005, Elsevier

    Prof Mark C Field

  154. Leishmania major: clathrin and adaptin complexes of an intra-cellular parasite

    Article • Experimental Parasitology, January 2005, Elsevier

    Prof Mark C Field

  155. Both of the Rab5 subfamily small GTPases of Trypanosoma brucei are essential and required for endocytosis

    Article • Molecular and Biochemical Parasitology, November 2004, Elsevier

    Prof Mark C Field, Belinda Hall

  156. Intracellular Membrane Transport Systems in Trypanosoma brucei

    Article • Traffic, October 2004, Wiley

    Prof Mark C Field

  157. TbRAB1 and TbRAB2 mediate trafficking through the early secretory pathway of Trypanosoma brucei

    Article • Molecular and Biochemical Parasitology, October 2004, Elsevier

    Prof Mark C Field

  158. New Approaches to the Microscopic Imaging of Trypanosoma brucei

    Article • Microscopy and Microanalysis, October 2004, Cambridge University Press

    Prof Mark C Field, Belinda Hall

  159. Cytoplasmic Targeting Signals in Transmembrane Invariant Surface Glycoproteins of Trypanosomes

    Article • Journal of Biological Chemistry, September 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Mark C Field

  160. TbRAB23; a nuclear-associated Rab protein from Trypanosoma brucei

    Article • Molecular and Biochemical Parasitology, August 2004, Elsevier

    Prof Mark C Field

  161. Rab4 Is an Essential Regulator of Lysosomal Trafficking in Trypanosomes

    Article • Journal of Biological Chemistry, July 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Mark C Field, Belinda Hall

  162. The Single Dynamin-like Protein of Trypanosoma brucei Regulates Mitochondrial Division and Is Not Required for Endocytosis

    Article • Journal of Biological Chemistry, December 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Mark C Field

  163. The Mechanism of Oxidative Stress Stabilization of the Thromboxane Receptor in COS-7 Cells

    Article • Journal of Biological Chemistry, October 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Mark C Field

  164. Clathrin-mediated endocytosis is essential in Trypanosoma brucei

    Article • The EMBO Journal, October 2003, Wiley

    Prof Mark C Field

  165. Rab5 and Rab11 mediate transferrin and anti-variant surface glycoprotein antibody recycling in Trypanosoma brucei

    Article • Biochemical Journal, September 2003, Portland Press Ltd.

    Prof Mark C Field, Belinda Hall

  166. Biochemical and genetic evidence for a family of heterotrimeric G-proteins in Trichomonas vaginalis

    Article • Molecular and Biochemical Parasitology, July 2003, Elsevier

    Prof Mark C Field

  167. RNAit: an automated web-based tool for the selection of RNAi targets in Trypanosoma brucei

    Article • Molecular and Biochemical Parasitology, April 2003, Elsevier

    Prof Mark C Field

  168. Endocytosis of a Glycosylphosphatidylinositol-anchored Protein via Clathrin-coated Vesicles, Sorting by Default in Endosomes, and Exocytosis via RAB11-positive Carriers

    Article • Molecular Biology of the Cell, February 2003, American Society for Cell Biology (ASCB)

    Prof Mark C Field

  169. Essential Roles for GPI-anchored Proteins in African Trypanosomes Revealed Using Mutants Deficient in GPI8

    Article • Molecular Biology of the Cell, December 2002, American Society for Cell Biology (ASCB)

    Prof Mark C Field

  170. The endocytic apparatus of the kinetoplastida. Part II: machinery and components of the system

    Article • Trends in Parasitology, December 2002, Elsevier

    Prof Mark C Field, Belinda Hall

  171. The kinetoplastida endocytic apparatus. Part I: a dynamic system for nutrition and evasion of host defences

    Article • Trends in Parasitology, November 2002, Elsevier

    Prof Mark C Field, Belinda Hall

  172. Leishmania RAB7: characterisation of terminal endocytic stages in an intracellular parasite

    Article • Molecular and Biochemical Parasitology, August 2002, Elsevier

    Prof Mark C Field

  173. Evidence for a non-LDL-mediated entry route for the trypanocidal drug suramin in Trypanosoma brucei

    Article • Molecular and Biochemical Parasitology, July 2002, Elsevier

    Prof Mark C Field, Belinda Hall

  174. TbRAB18, a developmentally regulated Golgi GTPase from Trypanosoma brucei

    Article • Molecular and Biochemical Parasitology, April 2002, Elsevier

    Prof Mark C Field

  175. Differential Endocytic Functions ofTrypanosoma brucei Rab5 Isoforms Reveal a Glycosylphosphatidylinositol-specific Endosomal Pathway

    Article • Journal of Biological Chemistry, December 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Mark C Field, Belinda Hall

  176. Isolation and Characterization of Subnuclear Compartments from Trypanosoma brucei

    Article • Journal of Biological Chemistry, October 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Mark C Field

  177. GPI-anchored proteins and glycoconjugates segregate into lipid rafts in Kinetoplastida

    Article • FEBS Letters, February 2001, Wiley

    Prof Mark C Field

  178. Export of a misprocessed GPI-anchored protein from the endoplasmic reticulum in vitro in an ATP- and cytosol-dependent manner

    Article • FEBS Letters, October 2000, Wiley

    Prof Mark C Field

  179. A Microsomal GTPase Is Required for Glycopeptide Export from the Mammalian Endoplasmic Reticulum

    Article • Journal of Biological Chemistry, July 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Mark C Field

  180. Erratum to “Cell-cycle and developmental regulation of TbRAB31 localisation, a GTP-locked Rab protein from Trypanosoma brucei”[Mol. Biochem. Parasitol. 106 (2000) 21–35]

    Article • Molecular and Biochemical Parasitology, April 2000, Elsevier

    Prof Mark C Field

  181. Acylation-dependent Protein Export in Leishmania

    Article • Journal of Biological Chemistry, April 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Mark C Field

  182. Cell-cycle and developmental regulation of TbRAB31 localisation, a GTP-locked Rab protein from Trypanosoma brucei

    Article • Molecular and Biochemical Parasitology, February 2000, Elsevier

    Prof Mark C Field

  183. The farnesyltransferase inhibitor manumycin A is a novel trypanocide with a complex mode of action including major effects on mitochondria

    Article • Molecular and Biochemical Parasitology, October 1999, Elsevier

    Prof Mark C Field

  184. GTPases in Protozoan Parasites: Tools for Cell Biology and Chemotherapy

    Article • Parasitology Today, September 1999, Elsevier

    Prof Mark C Field

  185. Complexity of Trypanosomatid Endocytosis Pathways Revealed by Rab4 and Rab5 Isoforms in Trypanosoma brucei

    Article • Journal of Biological Chemistry, November 1998, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Mark C Field

  186. Tandem Duplication of rab Genes Followed by Sequence Divergence and Acquisition of Distinct Functions in Trypanosoma brucei

    Article • Journal of Biological Chemistry, April 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Mark C Field

  187. Characterisation of protein isoprenylation in procyclic form Trypanosoma brucei

    Article • Molecular and Biochemical Parasitology, November 1996, Elsevier

    Prof Mark C Field

  188. Leptomonas seymouri, Trypanosoma brucei:A Method for Isolating Trypanosomatid Nuclear Factors Which BindT. bruceiSingle-Stranded g-Rich Telomere Sequence

    Article • Experimental Parasitology, June 1996, Elsevier

    Prof Mark C Field

  189. Sequence divergence in a family of variant surface glycoprotein genes from trypanosomes: Coding region hypervariability and downstream recombinogenic repeats

    Article • Journal of Molecular Evolution, May 1996, Springer Science + Business Media

    Prof Mark C Field

  190. Trypanosoma brucei: Molecular Cloning of Homologues of Small GTP-Binding Proteins Involved in Vesicle Trafficking

    Article • Experimental Parasitology, November 1995, Elsevier

    Prof Mark C Field

  191. A homologue of the nuclear GTPase Ran/TC4 from Trypanosoma brucei

    Article • Molecular and Biochemical Parasitology, January 1995, Elsevier

    Prof Mark C Field

  192. Molecular species analysis of phospholipids from Trypanosoma brucei bloodstream and procyclic forms

    Article • Molecular and Biochemical Parasitology, March 1993, Elsevier

    Professor Peter Bütikofer, Prof Mark C Field

  193. Characterization of a glycosylphosphatidylinositol membrane protein anchor precursor in Leishmania mexicana

    Article • Molecular and Biochemical Parasitology, October 1991, Elsevier

    Prof Mark C Field