All Stories

  1. Deletion of a Golgi protein in Trypanosoma cruzi reveals a critical role for Mn2+ in protein glycosylation needed for host cell invasion and intracellular replication

    Article • PLoS Pathogens, March 2021, PLOS

    Professor Roberto Docampo

  2. Affinity‐based proteomics reveals novel targets of inositol pyrophosphate (5‐IP 7 )‐dependent phosphorylation and binding in Trypanosoma cruzi replicative stages

    Article • Molecular Microbiology, January 2021, Wiley

    Professor Roberto Docampo

  3. Signaling pathways involved in environmental sensing in Trypanosoma cruzi

    Article • Molecular Microbiology, October 2020, Wiley

    Professor Roberto Docampo

  4. Inorganic Polyphosphate Interacts with Nucleolar and Glycosomal Proteins in Trypanosomatids

    Article • Molecular Microbiology, September 2018, Wiley

    Professor Roberto Docampo

  5. Novel hetero-oligomeric mitochondrial calcium uniporter (MCU) complex

    Article • mBio, September 2018, ASM Journals

    Professor Roberto Docampo

  6. An Intracellular Ammonium Transporter Is Necessary for Replication, Differentiation, and Resistance to Starvation and Osmotic Stress in Trypanosoma cruzi

    Article • mSphere, January 2018, ASM Journals

    Professor Roberto Docampo

  7. The inositol pyrophosphate synthesis pathway in Trypanosoma brucei is linked to polyphosphate synthesis in acidocalcisomes

    Article • Molecular Microbiology, August 2017, Wiley

    Professor Roberto Docampo

  8. Different Roles of Mitochondrial Calcium Uniporter Complex Subunits in Growth and Infectivity of Trypanosoma cruzi

    Article • mBio, May 2017, ASM Journals

    Professor Roberto Docampo

  9. CRISPR/Cas9-Induced Disruption of Paraflagellar Rod Protein 1 and 2 Genes in Trypanosoma cruzi Reveals Their Role in Flagellar Attachment

    Article • mBio, July 2015, ASM Journals

    Professor Roberto Docampo

  10. TcPho91 is a contractile vacuole phosphate sodium symporter that regulates phosphate and polyphosphate metabolism inTrypanosoma cruzi

    Article • Molecular Microbiology, June 2015, Wiley

    Professor Roberto Docampo

  11. Oxa, Thia, Heterocycle, and Carborane Analogues of SQ109: Bacterial and Protozoal Cell Growth Inhibitors

    Article • ACS Infectious Diseases, May 2015, American Chemical Society (ACS)

    Professor Roberto Docampo

  12. Aryloxyethyl Thiocyanates Are Potent Growth Inhibitors ofTrypanosoma cruziandToxoplasma gondii

    Article • ChemMedChem, April 2015, Wiley

    Professor Roberto Docampo

  13. Ca 2+ Regulation of Trypanosoma brucei Phosphoinositide Phospholipase C

    Article • Eukaryotic Cell, March 2015, ASM Journals

    Professor Roberto Docampo

  14. Proteomic analysis of acidocalcisomes ofTrypanosoma bruceiuncovers their role in phosphate metabolism, cation homeostasis, and calcium signaling

    Article • Communicative & Integrative Biology, March 2015, Taylor & Francis

    Professor Roberto Docampo

  15. Calcium signaling in trypanosomatid parasites

    Article • Cell Calcium, March 2015, Elsevier

    Professor Roberto Docampo

  16. SQ109, a New Drug Lead for Chagas Disease

    Article • Antimicrobial Agents and Chemotherapy, January 2015, ASM Journals

    Professor Roberto Docampo, Prof. Dr. Gustavo Benaim

  17. A novel role of Rab11 in trafficking GPI-anchored trans-sialidase to the plasma membrane of Trypanosoma cruzi

    Article • Small GTPases, January 2015, Taylor & Francis

    Professor Roberto Docampo

  18. Proteomic Analysis of the Acidocalcisome, an Organelle Conserved from Bacteria to Human Cells

    Article • PLoS Pathogens, December 2014, PLOS

    Professor Roberto Docampo

  19. Polyphosphate: a target for thrombosis attenuation

    Article • Blood, November 2014, American Society of Hematology

    Professor Roberto Docampo

  20. Intracellular calcium channels in protozoa

    Article • European Journal of Pharmacology, September 2014, Elsevier

    Professor Roberto Docampo

  21. Mitochondrial calcium transport in trypanosomes

    Article • Molecular and Biochemical Parasitology, September 2014, Elsevier

    Professor Roberto Docampo

  22. Rab11 Regulates Trafficking of Trans-sialidase to the Plasma Membrane through the Contractile Vacuole Complex of Trypanosoma cruzi

    Article • PLoS Pathogens, June 2014, PLOS

    Professor Roberto Docampo

  23. Squalene Synthase As a Target for Chagas Disease Therapeutics

    Article • PLoS Pathogens, May 2014, PLOS

    Professor Roberto Docampo

  24. The Streamlined Genome of Phytomonas spp. Relative to Human Pathogenic Kinetoplastids Reveals a Parasite Tailored for Plants

    Article • PLoS Genetics, February 2014, PLOS

    Professor Roberto Docampo, Professor Fred R. Opperdoes

  25. The Acidocalcisome Vacuolar Transporter Chaperone 4 Catalyzes the Synthesis of Polyphosphate in Insect-stages ofTrypanosoma bruceiandT. cruzi

    Article • Journal of Eukaryotic Microbiology, January 2014, Wiley

    Professor Roberto Docampo

  26. Letter from the Editor

    Article • Journal of Eukaryotic Microbiology, January 2014, Wiley

    Professor Roberto Docampo

  27. New insights into molecular recognition of 1,1-bisphosphonic acids by farnesyl diphosphate synthase

    Article • Bioorganic & Medicinal Chemistry, January 2014, Elsevier

    Professor Roberto Docampo

  28. Essential regulation of cell bioenergetics in Trypanosoma brucei by the mitochondrial calcium uniporter

    Article • Nature Communications, December 2013, Springer Science + Business Media

    Professor Roberto Docampo

  29. Design, synthesis and biological evaluation of WC-9 analogs as antiparasitic agents

    Article • European Journal of Medicinal Chemistry, November 2013, Elsevier

    Professor Roberto Docampo

  30. Evidence for the role of vacuolar soluble pyrophosphatase and inorganic polyphosphate inTrypanosoma cruzipersistence

    Article • Molecular Microbiology, September 2013, Wiley

    Professor Roberto Docampo

  31. Polyphosphate and Its Diverse Functions in Host Cells and Pathogens

    Article • PLoS Pathogens, May 2013, PLOS

    Professor Roberto Docampo

  32. Design, synthesis and biological evaluation of sulfur-containing 1,1-bisphosphonic acids as antiparasitic agents

    Article • European Journal of Medicinal Chemistry, February 2013, Elsevier

    Professor Roberto Docampo

  33. Calcium in Malaria Parasites

    Article • January 2013, Springer Science + Business Media

    Professor Roberto Docampo

  34. Letter from the Editor

    Article • Journal of Eukaryotic Microbiology, January 2013, Wiley

    Professor Roberto Docampo

  35. New Insights into Roles of Acidocalcisomes and Contractile Vacuole Complex in Osmoregulation in Protists

    Article • January 2013, Elsevier

    Professor Roberto Docampo

  36. Design, Synthesis, Calorimetry, and Crystallographic Analysis of 2-Alkylaminoethyl-1,1-bisphosphonates as Inhibitors of Trypanosoma cruzi Farnesyl Diphosphate Synthase

    Article • Journal of Medicinal Chemistry, July 2012, American Chemical Society (ACS)

    Dr Sandra B Gabelli, Dr Leon Mario Amzel, Professor Roberto Docampo

  37. Molecular and Electrophysiological Characterization of a Novel Cation Channel of Trypanosoma cruzi

    Article • PLoS Pathogens, June 2012, PLOS

    Professor Roberto Docampo

  38. Phosphonium lipocations as antiparasitic agents

    Article • Bioorganic & Medicinal Chemistry Letters, April 2012, Elsevier

    Professor Roberto Docampo

  39. Bisphosphonate metal complexes as selective inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase

    Article • Dalton Transactions, January 2012, Royal Society of Chemistry

    Professor Roberto Docampo

  40. 1-(Fluoroalkylidene)-1,1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthase

    Article • Organic & Biomolecular Chemistry, January 2012, Royal Society of Chemistry

    Professor Roberto Docampo

  41. Trypanosomes and the solution to a 50-year mitochondrial calcium mystery

    Article • Trends in Parasitology, January 2012, Elsevier

    Professor Roberto Docampo

  42. Bacterial and Archaeal Inclusions

    Article • December 2011, Wiley

    Dr Christiane Dahl, Dr Dennis A. Bazylinski, Professor Roberto Docampo

  43. Acidocalcisomes as Calcium- and Polyphosphate-Storage Compartments during Embryogenesis of the Insect Rhodnius prolixus Stahl

    Article • PLoS ONE, November 2011, PLOS

    Professor Roberto Docampo

  44. Molecular parasitology in the 21st Century

    Article • Essays in Biochemistry, October 2011, Portland Press Ltd.

    Professor Roberto Docampo

  45. Acidocalcisomes

    Article • Cell Calcium, August 2011, Elsevier

    Professor Roberto Docampo

  46. Volutin Granules of Eimeria Parasites are Acidic Compartments and Have Physiological and Structural Characteristics Similar to Acidocalcisomes

    Article • Journal of Eukaryotic Microbiology, June 2011, Wiley

    Professor Roberto Docampo

  47. Synthesis and biological evaluation of new 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase

    Article • Bioorganic & Medicinal Chemistry, April 2011, Elsevier

    Professor Roberto Docampo

  48. Identification of Contractile Vacuole Proteins in Trypanosoma cruzi

    Article • PLoS ONE, March 2011, PLOS

    Professor Roberto Docampo

  49. Inositolphosphoceramide Metabolism in Trypanosoma cruzi as Compared with other Trypanosomatids

    Article • Journal of Eukaryotic Microbiology, February 2011, Wiley

    Professor Roberto Docampo

  50. The Role of Acidocalcisomes in the Stress Response of Trypanosoma cruzi

    Article • January 2011, Elsevier

    Professor Roberto Docampo

  51. Risedronate metal complexes potentially active against Chagas disease

    Article • Journal of Inorganic Biochemistry, December 2010, Elsevier

    Professor Roberto Docampo

  52. Corrigendum: Acidic calcium stores open for business: expanding the potential for intracellular Ca2+ signaling

    Article • Trends in Cell Biology, November 2010, Elsevier

    Professor Roberto Docampo

  53. Defining the role of a FYVE domain in the localization and activity of a cAMP phosphodiesterase implicated in osmoregulation in Trypanosoma cruzi

    Article • Molecular Microbiology, October 2010, Wiley

    Professor Roberto Docampo

  54. Calcium- and polyphosphate-containing acidic granules of sea urchin eggs are similar to acidocalcisomes, but are not the targets for NAADP

    Article • Biochemical Journal, August 2010, Portland Press Ltd.

    Professor Roberto Docampo

  55. Calcium- and polyphosphate-containing acidocalcisomes in chicken egg yolk

    Article • Biology of the Cell, July 2010, Wiley

    Professor Roberto Docampo

  56. Acidic calcium stores open for business: expanding the potential for intracellular Ca2+ signaling

    Article • Trends in Cell Biology, May 2010, Elsevier

    Professor Roberto Docampo

  57. Biochemistry of Trypanosoma cruzi

    Article • January 2010, Elsevier

    Professor Roberto Docampo

  58. Calcium Homeostasis and Acidocalcisomes in Trypanosoma cruzi

    Article • January 2010, Springer Science + Business Media

    Professor Roberto Docampo

  59. In with the TRP Channels: Intracellular Functions for TRPM1 and TRPM2

    Article • Science Signaling, October 2009, American Association for the Advancement of Science

    Professor Roberto Docampo

  60. The Role of Acidocalcisomes in Parasitic Protists

    Article • Journal of Eukaryotic Microbiology, May 2009, Wiley

    Professor Roberto Docampo

  61. Trypanosoma cruzi: Antiproliferative effect of indole phytoalexins on intracellular amastigotes in vitro

    Article • Experimental Parasitology, May 2009, Elsevier

    Professor Roberto Docampo

  62. Proton-pyrophosphatase and polyphosphate in acidocalcisome-like vesicles from oocytes and eggs of Periplaneta americana

    Article • Insect Biochemistry and Molecular Biology, March 2009, Elsevier

    Professor Roberto Docampo

  63. Proteomics in Trypanosoma cruzi - localization of novel proteins to various organelles

    Article • PROTEOMICS, July 2008, Wiley

    Professor Roberto Docampo, Daniel Nilsson

  64. Farnesyl diphosphate synthase localizes to the cytoplasm of Trypanosoma cruzi and T. brucei

    Article • Experimental Parasitology, June 2008, Elsevier

    Professor Roberto Docampo

  65. Phospholipid and glycolipid composition of acidocalcisomes of Trypanosoma cruzi

    Article • Molecular and Biochemical Parasitology, April 2008, Elsevier

    Professor Roberto Docampo

  66. Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase

    Article • Bioorganic & Medicinal Chemistry, March 2008, Elsevier

    Professor Roberto Docampo

  67. The Acidocalcisome as a Target for Chemotherapeutic Agents in Protozoan Parasites

    Article • Current Pharmaceutical Design, March 2008, Bentham Science Publishers

    Professor Roberto Docampo

  68. Special section on novel organelles in parasitic protozoa

    Article • Experimental Parasitology, January 2008, Elsevier

    Professor Roberto Docampo

  69. A contractile vacuole complex is involved in osmoregulation in Trypanosoma cruzi

    Article • Experimental Parasitology, January 2008, Elsevier

    Professor Roberto Docampo

  70. Ablation of a small transmembrane protein of Trypanosoma brucei (TbVTC1) involved in the synthesis of polyphosphate alters acidocalcisome biogenesis and function, and leads to a cytokinesis defect

    Article • Biochemical Journal, October 2007, Portland Press Ltd.

    Professor Roberto Docampo

  71. Fluorine-containing aryloxyethyl thiocyanate derivatives are potent inhibitors of Trypanosoma cruzi and Toxoplasma gondii proliferation

    Article • Bioorganic & Medicinal Chemistry Letters, September 2007, Elsevier

    Professor Roberto Docampo

  72. Overexpression of a Zn2+-sensitive Soluble Exopolyphosphatase from Trypanosoma cruzi Depletes Polyphosphate and Affects Osmoregulation

    Article • Journal of Biological Chemistry, August 2007, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Roberto Docampo

  73. Ammonium production during hypo-osmotic stress leads to alkalinization of acidocalcisomes and cytosolic acidification in Trypanosoma cruzi

    Article • Molecular and Biochemical Parasitology, December 2006, Elsevier

    Professor Roberto Docampo

  74. Bacterial Inclusions

    Article • April 2006, Wiley

    Dr Christiane Dahl, Dr Dennis A. Bazylinski, Professor Roberto Docampo

  75. Synthesis and Biological Evaluation of 1-Amino-1,1-bisphosphonates Derived from Fatty Acids Against Trypanosoma cruzi Targeting Farnesyl Pyrophosphate Synthase.

    Article • ChemInform, January 2006, Wiley

    Professor Roberto Docampo

  76. Design, Synthesis, and Biological Evaluation of Phosphinopeptides against Trypanosoma cruzi Targeting Trypanothione Biosynthesis

    Article • Journal of Medicinal Chemistry, January 2006, American Chemical Society (ACS)

    Professor Roberto Docampo

  77. Role for a P-type H + -ATPase in the acidification of the endocytic pathway of Trypanosoma cruzi

    Article • Biochemical Journal, December 2005, Portland Press Ltd.

    Professor Roberto Docampo

  78. Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design

    Article • Proteins Structure Function and Bioinformatics, November 2005, Wiley

    Dr Sandra B Gabelli, Dr Leon Mario Amzel, Professor Roberto Docampo

  79. Synthesis and biological evaluation of 1-amino-1,1-bisphosphonates derived from fatty acids against Trypanosoma cruzi targeting farnesyl pyrophosphate synthase

    Article • Bioorganic & Medicinal Chemistry Letters, November 2005, Elsevier

    Professor Roberto Docampo

  80. Bisphosphonate Inhibition of the Exopolyphosphatase Activity of the Trypanosoma brucei Soluble Vacuolar Pyrophosphatase

    Article • Journal of Medicinal Chemistry, September 2005, American Chemical Society (ACS)

    Professor Roberto Docampo

  81. Acidocalcisomes ? conserved from bacteria to man

    Article • Nature Reviews Microbiology, March 2005, Springer Science + Business Media

    Professor Roberto Docampo

  82. P-type Proton ATPases are Involved in Intracellular Calcium and Proton Uptake in the Plant Parasite Phytomonas francai

    Article • Journal of Eukaryotic Microbiology, February 2005, Wiley

    Professor Roberto Docampo

  83. Leishmania salvage and remodelling of host sphingolipids in amastigote survival and acidocalcisome biogenesis

    Article • Molecular Microbiology, January 2005, Wiley

    Professor Roberto Docampo

  84. Acidocalcisomes and the Contractile Vacuole Complex Are Involved in Osmoregulation in Trypanosoma cruzi

    Article • Journal of Biological Chemistry, October 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Roberto Docampo

  85. New and Re-Emerging Infectious Diseases

    Article • Emerging Infectious Diseases, October 2004, Centers for Disease Control and Prevention (CDC)

    Professor Roberto Docampo

  86. Introduction: A Special Issue on Cellular Biology of Protozoan Parasites

    Article • Microscopy and Microanalysis, October 2004, Cambridge University Press

    Professor Roberto Docampo

  87. Polyphosphate Content and Fine Structure of Acidocalcisomes of Plasmodium falciparum

    Article • Microscopy and Microanalysis, October 2004, Cambridge University Press

    Professor Roberto Docampo

  88. Acidocalcisomes of Phytomonas françai Possess Distinct Morphological Characteristics and Contain Iron

    Article • Microscopy and Microanalysis, October 2004, Cambridge University Press

    Professor Roberto Docampo

  89. Crystallization and preliminary X-ray diffraction study of the farnesyl diphosphate synthase fromTrypanosoma brucei

    Article • Acta Crystallographica Section D Biological Crystallography, September 2004, International Union of Crystallography

    Professor Roberto Docampo

  90. Dynamics of polymorphism of acidocalcisomes in Leishmania parasites

    Article • Histochemistry and Cell Biology, May 2004, Springer Science + Business Media

    Professor Roberto Docampo

  91. Selective in vitro effects of the farnesyl pyrophosphate synthase inhibitor risedronate on Trypanosoma cruzi

    Article • International Journal of Antimicrobial Agents, March 2004, Elsevier

    Professor Roberto Docampo

  92. Antiparasitic activity of risedronate in a murine model of acute Chagas’ disease

    Article • International Journal of Antimicrobial Agents, March 2004, Elsevier

    Professor Roberto Docampo

  93. Specific chemotherapy of Chagas disease: controversies and advances

    Article • Trends in Parasitology, November 2003, Elsevier

    Professor Roberto Docampo

  94. Bisphosphonates derived from fatty acids are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase

    Article • Bioorganic & Medicinal Chemistry Letters, October 2003, Elsevier

    Professor Roberto Docampo

  95. New and Reemerging Infectious Diseases

    Article • Emerging Infectious Diseases, August 2003, Centers for Disease Control and Prevention (CDC)

    Professor Roberto Docampo

  96. Calcium regulation in protozoan parasites

    Article • Current Opinion in Microbiology, August 2003, Elsevier

    Professor Roberto Docampo

  97. Signaling in Trypanosoma cruzi

    Article • January 2003, Springer Science + Business Media

    Professor Roberto Docampo

  98. Fifth Annual Conference on New and Re-Emerging Infectious Diseases

    Article • Emerging Infectious Diseases, September 2002, Centers for Disease Control and Prevention (CDC)

    Professor Roberto Docampo

  99. Significant Differences Between Procyclic and Bloodstream Forms of Trypanosoma brucei in the Maintenance of their Plasma Membrane Potential

    Article • Journal of Eukaryotic Microbiology, September 2002, Wiley

    Professor Roberto Docampo

  100. New and re-emerging infectious diseases

    Article • Trends in Parasitology, August 2002, Elsevier

    Professor Roberto Docampo

  101. Design, Synthesis, and Biological Evaluation of Aryloxyethyl Thiocyanate Derivatives against Trypanosoma cruzi

    Article • Journal of Medicinal Chemistry, August 2002, American Chemical Society (ACS)

    Professor Roberto Docampo

  102. Radical Cure of Experimental Cutaneous Leishmaniasis by the Bisphosphonate Pamidronate

    Article • The Journal of Infectious Diseases, July 2002, Oxford University Press (OUP)

    Professor Roberto Docampo

  103. Magic-angle spinning31P NMR spectroscopy of condensed phosphates in parasitic protozoa: visualizing the invisible

    Article • FEBS Letters, June 2002, Wiley

    Professor Roberto Docampo

  104. A proton pumping pyrophosphatase in the Golgi apparatus and plasma membrane vesicles of Trypanosoma cruzi

    Article • Molecular and Biochemical Parasitology, April 2002, Elsevier

    Prof. Dr. Gustavo Benaim, Professor Roberto Docampo

  105. Proton and sodium pumps regulate the plasma membrane potential of different stages of Trypanosoma cruzi

    Article • Molecular and Biochemical Parasitology, March 2002, Elsevier

    Professor Roberto Docampo

  106. Overexpression of the Leishmania amazonensis Ca2+-ATPase gene lmaa1 enhances virulence

    Article • Cellular Microbiology, February 2002, Wiley

    Professor Roberto Docampo

  107. A plasma membrane P-type H+-ATPase regulates intracellular pH in Leishmania mexicana amazonensis

    Article • Molecular and Biochemical Parasitology, February 2002, Elsevier

    Professor Roberto Docampo

  108. The phosphatidylinositol-phospholipase C from Trypanosoma cruzi is active on inositolphosphoceramide

    Article • Molecular and Biochemical Parasitology, January 2002, Elsevier

    Professor Roberto Docampo

  109. The Sterol Composition of Trypanosoma cruzi Changes After Growth in Different Culture Media and Results in Different Sensitivity to Digitonin-Permeabilization

    Article • Journal of Eukaryotic Microbiology, September 2001, Wiley

    Professor Roberto Docampo

  110. Recent Developments in the Chemotherapy of Chagas Disease

    Article • Current Pharmaceutical Design, August 2001, Bentham Science Publishers

    Professor Roberto Docampo

  111. 31P NMR of Apicomplexans and the Effects of Risedronate on Cryptosporidium parvum Growth

    Article • Biochemical and Biophysical Research Communications, June 2001, Elsevier

    Professor Roberto Docampo

  112. Bisphosphonates as Chemotherapeutic Agents Against Trypanosomatid and Apicomplexan Parasites.

    Article • Current Drug Targets - Infectious Disorders, May 2001, Bentham Science Publishers

    Professor Roberto Docampo

  113. The acidocalcisome

    Article • Molecular and Biochemical Parasitology, May 2001, Elsevier

    Professor Roberto Docampo

  114. Bisphosphonates derived from fatty acids are potent growth inhibitors of Trypanosoma cruzi

    Article • Bioorganic & Medicinal Chemistry Letters, March 2001, Elsevier

    Professor Roberto Docampo

  115. Bisphosphonates Inhibit the Growth of Trypanosoma b rucei , Trypanosoma c ruzi , Leishmania d onovani , Toxoplasma g ondii , and Plasmodium f alciparum :  A Potential Route to Chemotherapy

    Article • Journal of Medicinal Chemistry, March 2001, American Chemical Society (ACS)

    Professor Roberto Docampo

  116. Third Annual Conference on New and Re-Emerging Infectious Diseases: in Honor of Norman Dion Levine

    Article • Acta Tropica, February 2001, Elsevier

    Professor Roberto Docampo

  117. Cloning and functional expression of a gene encoding a vacuolar-type proton-translocating pyrophosphatase from Trypanosoma cruzi

    Article • Biochemical Journal, October 2000, Portland Press Ltd.

    Professor Roberto Docampo

  118. Cloning and functional expression of a gene encoding a vacuolar-type proton-translocating pyrophosphatase from Trypanosoma cruzi

    Article • Biochemical Journal, October 2000, Portland Press Ltd.

    Professor Roberto Docampo

  119. New and Re-emerging Diseases

    Article • Parasitology Today, August 2000, Elsevier

    Professor Roberto Docampo

  120. Characterization of Isolated Acidocalcisomes of Trypanosoma cruzi

    Article • Journal of Biological Chemistry, May 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Roberto Docampo

  121. Presence of a Na+ /H+ exchanger in acidocalcisomes of Leishmania donovani and their alkalization by anti-leishmanial drugs

    Article • FEBS Letters, May 2000, Wiley

    Professor Roberto Docampo

  122. Design and Synthesis of Aryloxyethyl Thiocyanate Derivatives as Potent Inhibitors of Trypanosoma cruzi Proliferation

    Article • Journal of Medicinal Chemistry, May 2000, American Chemical Society (ACS)

    Professor Roberto Docampo

  123. The fine structure of acidocalcisomes in Trypanosoma cruzi

    Article • Parasitology Research, April 2000, Springer Science + Business Media

    Professor Roberto Docampo

  124. Acidocalcisomes and a vacuolar H+-pyrophosphatase in malaria parasites

    Article • Biochemical Journal, April 2000, Portland Press Ltd.

    Professor Roberto Docampo

  125. Acidocalcisomes and a vacuolar H+-pyrophosphatase in malaria parasites

    Article • Biochemical Journal, April 2000, Portland Press Ltd.

    Professor Roberto Docampo

  126. A pyruvate‒proton symport and an H+-ATPase regulate the intracellular pH of Trypanosoma brucei at different stages of its life cycle

    Article • Biochemical Journal, February 2000, Portland Press Ltd.

    Professor Roberto Docampo

  127. A pyruvate–proton symport and an H+-ATPase regulate the intracellular pH of Trypanosoma brucei at different stages of its life cycle

    Article • Biochemical Journal, February 2000, Portland Press Ltd.

    Professor Roberto Docampo

  128. Regulation of the plasma membrane potential inPneumocystis carinii

    Article • FEMS Microbiology Letters, February 2000, Oxford University Press (OUP)

    Professor Roberto Docampo

  129. Calcium mobilization by arachidonic acid in trypanosomatids

    Article • Molecular and Biochemical Parasitology, February 2000, Elsevier

    Professor Roberto Docampo

  130. Intracellular pH in mammalian stages of Trypanosoma cruzi is K+-dependent and regulated by H+-ATPases

    Article • Molecular and Biochemical Parasitology, February 2000, Elsevier

    Professor Roberto Docampo

  131. Sulphur-containing derivatives structurally related to fenoxycarb are potent growth inhibitors against the intracellular form of Trypanosoma cruzi

    Article • International Journal of Antimicrobial Agents, January 2000, Elsevier

    Professor Roberto Docampo

  132. Acidocalcisome: A Novel Ca2+ Storage Compartment in Trypanosomatids and Apicomplexan Parasites

    Article • Parasitology Today, November 1999, Elsevier

    Professor Roberto Docampo

  133. A plant-like vacuolar H+ -pyrophosphatase in Plasmodium falciparum

    Article • FEBS Letters, October 1999, Wiley

    Professor Roberto Docampo

  134. Presence of a vacuolar H+-pyrophosphatase in promastigotes of Leishmania donovani and its localization to a different compartment from the vacuolar H+-ATPase

    Article • Biochemical Journal, June 1999, Portland Press Ltd.

    Professor Roberto Docampo

  135. Presence of a vacuolar H+-pyrophosphatase in promastigotes of Leishmania donovani and its localization to a different compartment from the vacuolar H+-ATPase

    Article • Biochemical Journal, June 1999, Portland Press Ltd.

    Professor Roberto Docampo

  136. Mercaptopyridine- N -oxide, an NADH-fumarate reductase inhibitor, blocks Trypanosoma cruzi growth in culture and in infected myoblasts

    Article • FEMS Microbiology Letters, June 1999, Oxford University Press (OUP)

    Professor Roberto Docampo

  137. Functional expression of a vacuolar-type H+-ATPase in the plasma membrane and intracellular vacuoles of Trypanosoma cruzi

    Article • Biochemical Journal, June 1998, Portland Press Ltd.

    Professor Roberto Docampo

  138. Analysis of the uptake of the fluorescent marker 2′,7′-bis-(2-carboxyethyl)-5(and-6)-carboxyfluorescein (BCECF) by hydrogenosomes in Trichomonas vaginalis

    Article • European Journal of Cell Biology, June 1998, Elsevier

    Professor Roberto Docampo

  139. Ecto-protein tyrosine phosphatase activity in Trypanosoma cruzi infective stages

    Article • Molecular and Biochemical Parasitology, May 1998, Elsevier

    Professor Roberto Docampo

  140. Two types of H+-ATPase are involved in the acidification of internal compartments in Trypanosoma cruzi

    Article • Biochemical Journal, April 1998, Portland Press Ltd.

    Professor Roberto Docampo

  141. Tyrosine phosphate hydrolysis of host proteins by Trypanosoma cruzi is linked to cell invasion

    Article • FEMS Microbiology Letters, April 1998, Oxford University Press (OUP)

    Professor Roberto Docampo

  142. Structure−Activity Relationship of New Growth Inhibitors of Trypanosoma cruzi

    Article • Journal of Medicinal Chemistry, April 1998, American Chemical Society (ACS)

    Professor Roberto Docampo

  143. Inhibition of Ca2+ release from Trypanosoma brucei acidocalcisomes by 3,5-dibutyl-4-hydroxytoluene: role of the Na+/H+ exchanger

    Article • Biochemical Journal, December 1997, Portland Press Ltd.

    Professor Roberto Docampo

  144. Design, Synthesis, and Biological Evaluation of New Growth Inhibitors of Trypanosoma cruzi (Epimastigotes)

    Article • Journal of Medicinal Chemistry, July 1997, American Chemical Society (ACS)

    Professor Roberto Docampo

  145. Sterol biosynthesis inhibitors: Potential chemotherapeutics against chagas disease

    Article • Parasitology Today, April 1997, Elsevier

    Professor Roberto Docampo

  146. Inhibition of Trypanosoma cruzi and T. brucei NADH fumarate reductase by benznidazole and anthelmintic imidazole derivatives

    Article • Molecular and Biochemical Parasitology, November 1996, Elsevier

    Professor Roberto Docampo

  147. Biological evaluation of two potent inhibitors of Trypanosoma cruzi epimastigotes against the intracellular form of the parasite

    Article • Bioorganic & Medicinal Chemistry Letters, November 1996, Elsevier

    Professor Roberto Docampo

  148. The role of a H+-ATPase in the regulation of cytoplasmic pH inTrypanosoma cruziepimastigotes

    Article • Biochemical Journal, August 1996, Portland Press Ltd.

    Professor Roberto Docampo, Prof. Dr. Gustavo Benaim

  149. Phosphatidylethanol stimulates the plasma-membrane calcium pump from human erythrocytes

    Article • Biochemical Journal, August 1996, Portland Press Ltd.

    Professor Roberto Docampo, Prof. Dr. Gustavo Benaim

  150. An H + -ATPase regulates cytoplasmic pH in Pneumocystis carinii trophozoites

    Article • Biochemical Journal, June 1996, Portland Press Ltd.

    Professor Roberto Docampo

  151. Sodium-proton exchange stimulates Ca 2+ release from acidocalcisomes of Trypanosoma brucei

    Article • Biochemical Journal, April 1996, Portland Press Ltd.

    Professor Roberto Docampo

  152. The role of Ca2+ in the process of cell invasion by intracellular parasites

    Article • Parasitology Today, February 1996, Elsevier

    Professor Roberto Docampo

  153. Calcium regulation of cellular functions

    Article • Parasitology Today, September 1995, Elsevier

    Professor Roberto Docampo

  154. Inhibition of Protein Synthesis and Amino Acid Transport by Crystal Violet in Trypanosoma cruzi

    Article • Journal of Eukaryotic Microbiology, May 1995, Wiley

    Professor Roberto Docampo

  155. Antioxidant Mechanisms

    Article • January 1995, Elsevier

    Professor Roberto Docampo

  156. Inhibition of Trypanosoma cruzi trypanothione reductase by crystal violet

    Article • Molecular and Biochemical Parasitology, October 1994, Elsevier

    Professor Roberto Docampo

  157. Trypanothione-dependent peroxide metabolism in Trypanosoma cruzi different stages

    Article • Molecular and Biochemical Parasitology, September 1993, Elsevier

    Professor Roberto Docampo

  158. Effect of thapsigargin on calcium homeostasis in Trypanosoma cruzi trypomastigotes and epimastigotes

    Article • Molecular and Biochemical Parasitology, June 1993, Elsevier

    Professor Roberto Docampo

  159. Energization-dependent Ca2+ accumulation in Trypanosoma brucei bloodstream and procyclic trypomastigotes mitochondria

    Article • Molecular and Biochemical Parasitology, December 1992, Elsevier

    Professor Roberto Docampo

  160. Evidence for free radical formation during horseradish peroxidase-catalyzed N-demethylation of crystal violet

    Article • Chemico-Biological Interactions, November 1992, Elsevier

    Professor Roberto Docampo

  161. Calcium homeostasis in Trypanosoma cruzi amastigotes: presence of inositol phosphates and lack of an inositol 1,4,5-trisphosphate-sensitive calcium pool

    Article • Molecular and Biochemical Parasitology, June 1992, Elsevier

    Professor Roberto Docampo

  162. The inositol phosphate/diacylglycerol signalling pathway in Trypanosoma cruzi

    Article • Biochemical Journal, April 1991, Portland Press Ltd.

    Professor Roberto Docampo

  163. Ca2+ transport in digitonin-permeabilized trypanosomatids

    Article • Molecular and Biochemical Parasitology, August 1990, Elsevier

    Professor Roberto Docampo

  164. Sensitivity of parasites to free radical damage by antiparasitic drugs

    Article • Chemico-Biological Interactions, January 1990, Elsevier

    Professor Roberto Docampo

  165. The Metabolism and Mode of Action of Gentian Violet

    Article • Drug Metabolism Reviews, January 1990, Taylor & Francis

    Professor Roberto Docampo

  166. Characteristics of Ca2+ transport by Trypanosoma cruzi mitochondria in situ

    Article • Archives of Biochemistry and Biophysics, July 1989, Elsevier

    Professor Roberto Docampo

  167. Enhancement of the cytotoxicity of crystal violet against Trypanosoma cruzi in the blood by ascorbate

    Article • Molecular and Biochemical Parasitology, January 1988, Elsevier

    Professor Roberto Docampo

  168. Reduction of 5-Nitroimidazoles, Nitrofurazone, and 2,4-Dinitrophenol to their Free Radical Metabolites by Tritrichomonas Foetus Hydrogenosomes

    Article • January 1988, Springer Science + Business Media

    Professor Roberto Docampo

  169. Generation of superoxide anion and hydrogen peroxide during redox cycling of 5-(4-nitrophenyl)penta-2,4-dienal by mammalian microsomes and enzymes

    Article • Chemico-Biological Interactions, January 1988, Elsevier

    Professor Roberto Docampo

  170. Reduction of the metallochromic indicators murexide and tetramethylmurexide to their free radical metabolites by cytoplasmic enzymes and reducing agents

    Article • Chemico-Biological Interactions, January 1986, Elsevier

    Professor Roberto Docampo

  171. Photosensitization by the trypanocidal agent crystal violet. Type i versus type II reactions

    Article • Chemico-Biological Interactions, January 1986, Elsevier

    Professor Roberto Docampo

  172. Mechanism of Toxicity of Nitro Compounds Used in the Chemotherapy of Trichomoniasis

    Article • Environmental Health Perspectives, December 1985, JSTOR

    Professor Roberto Docampo

  173. Mechanism of toxicity of nitro compounds used in the chemotherapy of trichomoniasis

    Article • Environmental Health Perspectives, December 1985, Environmental Health Perspectives

    Professor Roberto Docampo

  174. Reduction of the metallochromic indicators arsenazo III and antipyrylazo III to their free radical metabolites by cytoplasmic enzymes

    Article • FEBS Letters, January 1985, Wiley

    Professor Roberto Docampo

  175. On the mechanism of killing ofTrypanosoma cruzi by human polymorphonuclear leukocytes

    Article • Cellular and Molecular Life Sciences, January 1985, Springer Science + Business Media

    Professor Roberto Docampo

  176. Free-Radical Intermediates in the Antiparasitic Action of Drugs and Phagocytic Cells

    Article • January 1984, Elsevier

    Professor Roberto Docampo

  177. Oxygen-derived radicals fromTrypanosoma cruzi-stimulated human neutrophils

    Article • FEBS Letters, May 1983, Wiley

    Professor Roberto Docampo

  178. Increased biliary secretion and loss of hepatic glutathione in rat liver after nifurtimox treatment

    Article • Biochemical Pharmacology, February 1983, Elsevier

    Professor Roberto Docampo

  179. Subcellular localization of phosphoenolpyruvate carboxykinase in the trypanosomatids Trypanosoma cruzi and Crithidia fasciculata

    Article • Molecular and Biochemical Parasitology, September 1982, Elsevier

    Professor Roberto Docampo

  180. Metabolic Requirements for the Damage of Trypanosoma cruzi Epimastigotes by Human Polymorphonuclear Leukocytes

    Article • Journal of Parasitology, August 1982, JSTOR

    Professor Roberto Docampo

  181. Porphyrin biosynthesis in parasitic hemoflagellates: Functional and defective enzymes in Trypanosoma cruzi

    Article • Comparative Biochemistry and Physiology Part B Comparative Biochemistry, January 1982, Elsevier

    Professor Roberto Docampo

  182. Mechanism of nifurtimox toxicity in different forms of Trypanosoma cruzi

    Article • Biochemical Pharmacology, July 1981, Elsevier

    Professor Roberto Docampo

  183. Biochemical and ultrastructural alterations produced by miconazole and econazole in Trypanosoma cruzi

    Article • Molecular and Biochemical Parasitology, July 1981, Elsevier

    Professor Roberto Docampo

  184. Evaluation of the toxicity of 3-allyl-β-lapachone against Trypanosma cruzi bloodstream forms

    Article • Molecular and Biochemical Parasitology, January 1980, Elsevier

    Professor Roberto Docampo

  185. Generation of superoxide anion and hydrogen peroxide induced by nifurtimox in Trypanosoma cruzi

    Article • Archives of Biochemistry and Biophysics, October 1979, Elsevier

    Professor Roberto Docampo

  186. Acetate Oxidation by Bloodstream Forms ofTrypanosoma cruzi*

    Article • The Journal of Protozoology, May 1979, Wiley

    Professor Roberto Docampo

  187. β-lapachone enhancement of lipid peroxidation and superoxide anion and hydrogen peroxide formation by Sarcoma 180 ascites tumor cells

    Article • Biochemical Pharmacology, March 1979, Elsevier

    Professor Roberto Docampo

  188. Trypanosoma cruzi: Effect of olivacine on macromolecular synthesis, ultrastructure, and respiration of epimastigotes

    Article • Experimental Parasitology, August 1978, Elsevier

    Professor Roberto Docampo

  189. Lipid peroxidation and the generation of free radicals, superoxide anion, and hydrogen peroxide in β-lapachone-treated Trypanosoma cruzi epimastigotes

    Article • Archives of Biochemistry and Biophysics, March 1978, Elsevier

    Professor Roberto Docampo

  190. Superoxide anion production and trypanocidal action of naphthoquinones on Trypanosoma cruzi

    Article • Comparative Biochemistry and Physiology Part C Comparative Pharmacology, January 1978, Elsevier

    Professor Roberto Docampo

  191. Trypanosoma cruzi: Ultrastructural and metabolic alterations of epimastigotes by β-lapachone

    Article • Experimental Parasitology, June 1977, Elsevier

    Professor Roberto Docampo

  192. Localization of peroxidase activity inTrypanosoma cruzi microbodies

    Article • Cellular and Molecular Life Sciences, August 1976, Springer Science + Business Media

    Professor Roberto Docampo

  193. Acidocalcisomes and Polyphosphate Granules

    Article • Springer Science + Business Media

    Professor Roberto Docampo