All Stories

  1. Hallmarks of Cancer Affected by the MIF Cytokine Family

    Article • Cancers, January 2023, MDPI AG

    Prof. Dr. ir. Benoit Stijlemans

  2. The Trypanosomal Transferrin Receptor of Trypanosoma Brucei—A Review

    Article • Tropical Medicine and Infectious Disease, October 2019, MDPI AG

    Prof. Dr. ir. Benoit Stijlemans

  3. Novel half-life extended anti-MIF nanobodies protect against endotoxic shock

    Article • The FASEB Journal, June 2018, Federation of American Societies For Experimental Biology (FASEB)

    Prof. Dr. ir. Benoit Stijlemans

  4. The anuran skin peptide bradykinin mediates its own absorption across epithelial barriers of the digestive tract

    Article • Peptides, March 2018, Elsevier

    Prof. Dr. ir. Benoit Stijlemans

  5. African Trypanosomiasis-Associated Anemia: The Contribution of the Interplay between Parasites and the Mononuclear Phagocyte System

    Article • Frontiers in Immunology, February 2018, Frontiers

    Prof. Dr. ir. Benoit Stijlemans

  6. MIF inhibition interferes with the inflammatory and T cell-stimulatory capacity of NOD macrophages and delays autoimmune diabetes onset

    Article • PLoS ONE, November 2017, PLOS

    Prof. Dr. ir. Benoit Stijlemans

  7. Nanobodies As Tools to Understand, Diagnose, and Treat African Trypanosomiasis

    Article • Frontiers in Immunology, June 2017, Frontiers

    Prof. Dr. ir. Benoit Stijlemans

  8. Reprint of: The non-mammalian MIF superfamily

    Article • Immunobiology, June 2017, Elsevier

    Prof. Dr. ir. Benoit Stijlemans

  9. African Trypanosomes Undermine Humoral Responses and Vaccine Development: Link with Inflammatory Responses?

    Article • Frontiers in Immunology, May 2017, Frontiers

    Prof. Dr. ir. Benoit Stijlemans

  10. The non-mammalian MIF superfamily

    Article • Immunobiology, March 2017, Elsevier

    Prof. Dr. ir. Benoit Stijlemans

  11. Early Immunological Responses Upon Tsetse Fly–Mediated Trypanosome Inoculation

    Article • January 2017, Elsevier

    Prof. Dr. ir. Benoit Stijlemans

  12. Immune Evasion Strategies of Trypanosoma brucei within the Mammalian Host: Progression to Pathogenicity

    Article • Frontiers in Immunology, June 2016, Frontiers

    Prof. Dr. ir. Benoit Stijlemans

  13. An Anti-proteome Nanobody Library Approach Yields a Specific Immunoassay for Trypanosoma congolense Diagnosis Targeting Glycosomal Aldolase

    Article • PLoS Neglected Tropical Diseases, February 2016, PLOS

    Prof. Dr. ir. Benoit Stijlemans

  14. The Possible Role of Staphylococcus epidermidis LPxTG Surface Protein SesC in Biofilm Formation

    Article • PLoS ONE, January 2016, PLOS

    Prof. Dr. ir. Benoit Stijlemans

  15. E-cadherin expression in macrophages dampens their inflammatory responsiveness in vitro, but does not modulate M2-regulated pathologies in vivo

    Article • Scientific Reports, July 2015, Nature

    Prof. Dr. ir. Benoit Stijlemans

  16. NK-, NKT- and CD8-Derived IFNγ Drives Myeloid Cell Activation and Erythrophagocytosis, Resulting in Trypanosomosis-Associated Acute Anemia

    Article • PLoS Pathogens, June 2015, PLOS

    Prof. Dr. ir. Benoit Stijlemans

  17. Development of a pHrodo-Based Assay for the Assessment of In Vitro and In Vivo Erythrophagocytosis during Experimental Trypanosomosis

    Article • PLoS Neglected Tropical Diseases, March 2015, PLOS

    Prof. Dr. ir. Benoit Stijlemans

  18. Monitoring liver macrophages using nanobodies targeting Vsig4: Concanavalin A induced acute hepatitis as paradigm

    Article • Immunobiology, February 2015, Elsevier

    Prof. Dr. ir. Benoit Stijlemans

  19. Murine Liver Myeloid Cell Isolation Protocol

    Article • BIO-PROTOCOL, January 2015, Bio-Protocol, LLC

    Prof. Dr. ir. Benoit Stijlemans

  20. Iron Homeostasis andTrypanosoma bruceiAssociated Immunopathogenicity Development: A Battle/Quest for Iron

    Article • BioMed Research International, January 2015, Hindawi Publishing Corporation

    Prof. Dr. ir. Benoit Stijlemans

  21. Generation of a Nanobody Targeting the Paraflagellar Rod Protein of Trypanosomes

    Article • PLoS ONE, December 2014, PLOS

    Prof. Dr. ir. Benoit Stijlemans

  22. MIF Contributes to Trypanosoma brucei Associated Immunopathogenicity Development

    Article • PLoS Pathogens, September 2014, PLOS

    Prof. Dr. ir. Benoit Stijlemans

  23. Antibody-mediated control ofTrypanosoma vivaxinfection fails in the absence of tumour necrosis factor

    Article • Parasite Immunology, May 2014, Wiley

    Prof. Dr. ir. Benoit Stijlemans

  24. Presence and regulation of insulin-regulated aminopeptidase in mouse macrophages

    Article • Journal of the Renin-Angiotensin-Aldosterone System, February 2014, SAGE Publications

    Prof. Dr. ir. Benoit Stijlemans

  25. Low Structural Variation in the Host-Defense Peptide Repertoire of the Dwarf Clawed Frog Hymenochirus boettgeri (Pipidae)

    Article • PLoS ONE, January 2014, PLOS

    Prof. Dr. ir. Benoit Stijlemans

  26. African Trypanosomiasis as Paradigm for Involvement of the Mononuclear Phagocyte System in Pathogenicity During Parasite Infection

    Article • January 2014, Springer Science + Business Media

    Prof. Dr. ir. Benoit Stijlemans

  27. A Trypanosoma brucei Kinesin Heavy Chain Promotes Parasite Growth by Triggering Host Arginase Activity

    Article • PLoS Pathogens, October 2013, PLOS

    Prof. Dr. ir. Benoit Stijlemans

  28. Origin and Functional Diversification of an Amphibian Defense Peptide Arsenal

    Article • PLoS Genetics, August 2013, PLOS

    Prof. Dr. ir. Benoit Stijlemans

  29. Characterization of central macrophages in Anemia of Inflammation (AI): African trypanosomiasis as a model system

    Article • Frontiers in Immunology, January 2013, Frontiers

    Prof. Dr. ir. Benoit Stijlemans

  30. Affinity Is an Important Determinant of the Anti-Trypanosome Activity of Nanobodies

    Article • PLoS Neglected Tropical Diseases, November 2012, PLOS

    Prof. Dr. ir. Benoit Stijlemans

  31. Tsetse Salivary Gland Proteins 1 and 2 Are High Affinity Nucleic Acid Binding Proteins with Residual Nuclease Activity

    Article • PLoS ONE, October 2012, PLOS

    Prof. Dr. ir. Benoit Stijlemans

  32. Vaccination with SesC Decreases Staphylococcus epidermidis Biofilm Formation

    Article • Infection and Immunity, July 2012, ASM Journals

    Prof. Dr. ir. Benoit Stijlemans

  33. Expression and extracellular release of a functional anti-trypanosome Nanobody® in Sodalis glossinidius, a bacterial symbiont of the tsetse fly

    Article • Microbial Cell Factories, January 2012, Springer Science + Business Media

    Prof. Dr. ir. Benoit Stijlemans

  34. Similar inflammatory DC maturation signatures induced by TNF or Trypanosoma brucei antigens instruct default Th2-cell responses

    Article • European Journal of Immunology, November 2011, Wiley

    Prof. Dr. ir. Benoit Stijlemans

  35. IL-10 limits production of pathogenic TNF by M1 myeloid cells through induction of nuclear NF-κB p50 member inTrypanosoma congolenseinfection-resistant C57BL/6 mice

    Article • European Journal of Immunology, September 2011, Wiley

    Prof. Dr. ir. Benoit Stijlemans

  36. High Affinity Nanobodies against the Trypanosome brucei VSG Are Potent Trypanolytic Agents that Block Endocytosis

    Article • PLoS Pathogens, June 2011, PLOS

    Prof Mark C Field, Prof. Dr. ir. Benoit Stijlemans

  37. Lack of galectin-3 alleviates trypanosomiasis-associated anemia of inflammation

    Article • Immunobiology, September 2010, Elsevier

    Prof. Dr. ir. Benoit Stijlemans

  38. Tip-DC Development during Parasitic Infection Is Regulated by IL-10 and Requires CCL2/CCR2, IFN-γ and MyD88 Signaling

    Article • PLoS Pathogens, August 2010, PLOS

    Prof. Dr. ir. Benoit Stijlemans

  39. Current status of vaccination against African trypanosomiasis

    Article • Parasitology, May 2010, Cambridge University Press

    Prof. Dr. ir. Benoit Stijlemans

  40. Scrutinizing the mechanisms underlying the induction of anemia of inflammation through GPI-mediated modulation of macrophage activation in a model of African trypanosomiasis

    Article • Microbes and Infection, May 2010, Elsevier

    Prof. Dr. ir. Benoit Stijlemans

  41. The Central Role of Macrophages in Trypanosomiasis-Associated Anemia:Rationale for Therapeutical Approaches

    Article • Endocrine Metabolic & Immune Disorders - Drug Targets, March 2010, Bentham Science Publishers

    Prof. Dr. ir. Benoit Stijlemans

  42. Identification of a Parasitic Immunomodulatory Protein Triggering the Development of Suppressive M1 Macrophages during African Trypanosomiasis

    Article • The Journal of Infectious Diseases, December 2009, Oxford University Press (OUP)

    Prof. Dr. ir. Benoit Stijlemans

  43. Differentiation, activation and function of CD11b+Ly6C+ TNF/iNOS-producing dendritic cells during parasitic infection

    Article • Cytokine, October 2009, Elsevier

    Prof. Dr. ir. Benoit Stijlemans

  44. Understanding the role of monocytic cells in liver inflammation using parasite infection as a model

    Article • Immunobiology, September 2009, Elsevier

    Prof. Dr. ir. Benoit Stijlemans

  45. Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice

    Article • Journal of Clinical Investigation, June 2009, American Society for Clinical Investigation

    Prof. Dr. ir. Benoit Stijlemans

  46. Role of iron homeostasis in trypanosomiasis-associated anemia

    Article • Immunobiology, November 2008, Elsevier

    Prof. Dr. ir. Benoit Stijlemans

  47. Parallel selection of multiple anti-infectome Nanobodies without access to purified antigens

    Article • Journal of Immunological Methods, January 2008, Elsevier

    Prof. Dr. ir. Benoit Stijlemans

  48. A Glycosylphosphatidylinositol-Based Treatment Alleviates Trypanosomiasis-Associated Immunopathology

    Article • The Journal of Immunology, September 2007, The American Association of Immunologists

    Prof. Dr. ir. Benoit Stijlemans

  49. African trypanosomosis: From immune escape and immunopathology to immune intervention

    Article • Veterinary Parasitology, August 2007, Elsevier

    Prof. Dr. ir. Benoit Stijlemans

  50. Traitement expérimental de la trypanosomiase africaine par le facteur trypanolytique humain combiné à un nanocorps

    Article • médecine/sciences, November 2006, EDP Sciences

    Prof. Dr. ir. Benoit Stijlemans

  51. Evidence for proteins involved in prophenoloxidase cascade Eisenia fetida earthworms

    Article • Journal of Comparative Physiology B, April 2006, Springer Science + Business Media

    Prof. Dr. ir. Benoit Stijlemans

  52. Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor

    Article • Nature Medicine, April 2006, Nature

    Prof. Dr. ir. Benoit Stijlemans

  53. Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH

    Article • Journal of Molecular Biology, July 2005, Elsevier

    Prof. Dr. ir. Benoit Stijlemans

  54. P75 Tumor Necrosis Factor–Receptor Shedding Occurs as a Protective Host Response during African Trypanosomiasis

    Article • The Journal of Infectious Diseases, February 2004, Oxford University Press (OUP)

    Prof. Dr. ir. Benoit Stijlemans

  55. Efficient Targeting of Conserved Cryptic Epitopes of Infectious Agents by Single Domain Antibodies

    Article • Journal of Biological Chemistry, October 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof. Dr. ir. Benoit Stijlemans

  56. VSG-GPI anchors of African trypanosomes: their role in macrophage activation and induction of infection-associated immunopathology

    Article • Microbes and Infection, July 2002, Elsevier

    Prof. Dr. ir. Benoit Stijlemans

  57. Distinct Carbohydrate Recognition Domains of an Invertebrate Defense Molecule Recognize Gram-negative and Gram-positive Bacteria

    Article • Journal of Biological Chemistry, October 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof. Dr. ir. Benoit Stijlemans

  58. Attenuation ofTrypanosoma bruceiIs Associated with Reduced Immunosuppression and Concomitant Production of Th2 Lymphokines

    Article • The Journal of Infectious Diseases, March 2000, Oxford University Press (OUP)

    Prof. Dr. ir. Benoit Stijlemans

  59. Detection of clinically relevant antibodies pretransplant and posttransplant with PRA-STAT

    Article • Transplantation Proceedings, February 1997, Elsevier

    Prof. Dr. ir. Benoit Stijlemans