All Stories

  1. Collaborative evaluation of in silico predictions for high throughput toxicokinetics

    Article • Toxicology in Vitro, January 2026, Elsevier

    Dr John Fredrick Wambaugh

  2. Interpretation of thyroid-relevant bioactivity data for comparison to in vivo exposures: A prioritization approach for putative chemical inhibitors of in vitro deiodinase activity

    Article • Toxicology, August 2025, Elsevier

    Dr John Fredrick Wambaugh

  3. Applying New Approach Methods for Toxicokinetics for Chemical Risk Assessment

    Article • Chemical Research in Toxicology, July 2025, American Chemical Society (ACS)

    Dr John Fredrick Wambaugh

  4. Insights derived from testing a library of per- and polyfluoroalkyl substances (PFAS) in a battery of new approach methods (NAMs)

    Article • Journal of Toxicology and Environmental Health Part B, July 2025, Taylor & Francis

    Dr Richard S Judson, Dr John Fredrick Wambaugh

  5. Informatics for toxicokinetics

    Article • Journal of Pharmacokinetics and Pharmacodynamics, May 2025, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  6. Enabling transparent toxicokinetic modeling for public health risk assessment

    Article • PLOS One, April 2025, PLOS

    Dr John Fredrick Wambaugh

  7. Integration of new approach methods for the assessment of data-poor chemicals

    Article • Toxicological Sciences, February 2025, Oxford University Press (OUP)

    Dr Richard S Judson, Dr John Fredrick Wambaugh

  8. A Simple Physiologically Based Toxicokinetic Model for Multi-Route In Vitro–In Vivo Extrapolation

    Article • Environmental Science & Technology Letters, February 2025, American Chemical Society (ACS)

    Dr John Fredrick Wambaugh

  9. Developing Chemical Signatures for Categories of Household Consumer Products Using Suspect Screening Analysis

    Article • Environmental Science & Technology, January 2025, American Chemical Society (ACS)

    Dr Antony John Williams, Dr John Fredrick Wambaugh

  10. Discerning Emittable from Extractable Chemicals Identified in Consumer Products by Suspect Screening GCxGC-TOFMS

    Article • Environmental Science & Technology, November 2024, American Chemical Society (ACS)

    Dr John Fredrick Wambaugh

  11. In Vitro Hepatic Clearance Evaluations of Per- and Polyfluoroalkyl Substances (PFAS) across Multiple Structural Categories

    Article • Toxics, September 2024, MDPI AG

    Dr John Fredrick Wambaugh

  12. Development of chemical categories for per- and polyfluoroalkyl substances (PFAS) and the proof-of-concept approach to the identification of potential candidates for tiered toxicological testing and human health assessment

    Article • Computational Toxicology, September 2024, Elsevier

    Dr John Fredrick Wambaugh

  13. A Comparison of In Vitro Points of Departure with Human Blood Levels for Per- and Polyfluoroalkyl Substances (PFAS)

    Article • Toxics, April 2024, MDPI AG

    Dr Richard S Judson, Dr John Fredrick Wambaugh

  14. Suspect Screening Analysis of Pooled Human Serum Samples Using GC × GC/TOF-MS

    Article • Environmental Science & Technology, January 2024, American Chemical Society (ACS)

    Dr John Fredrick Wambaugh

  15. Impact of gut permeability on estimation of oral bioavailability for chemicals in commerce and the environment

    Article • ALTEX, January 2024, ALTEX Edition

    Dr John Fredrick Wambaugh

  16. Characterizing Chemical Exposure Trends from NHANES Urinary Biomonitoring Data

    Article • Environmental Health Perspectives, January 2024, Environmental Health Perspectives

    Dr John Fredrick Wambaugh

  17. Trust your gut: Establishing confidence in gastrointestinal models - An overview of the state of the science and contexts of use

    Article • ALTEX, January 2024, ALTEX Edition

    Dr John Fredrick Wambaugh

  18. Reproducibility of organ-level effects in repeat dose animal studies

    Article • Computational Toxicology, November 2023, Elsevier

    Dr John Fredrick Wambaugh

  19. Cutting-edge computational chemical exposure research at the U.S. Environmental Protection Agency

    Article • Environment International, August 2023, Elsevier

    Dr John Fredrick Wambaugh

  20. Application of Cell Painting for chemical hazard evaluation in support of screening-level chemical assessments

    Article • Toxicology and Applied Pharmacology, June 2023, Elsevier

    Dr John Fredrick Wambaugh

  21. Screening for drinking water contaminants of concern using an automated exposure-focused workflow

    Article • Journal of Exposure Science & Environmental Epidemiology, May 2023, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  22. Category-Based Toxicokinetic Evaluations of Data-Poor Per- and Polyfluoroalkyl Substances (PFAS) using Gas Chromatography Coupled with Mass Spectrometry

    Article • Toxics, May 2023, MDPI AG

    Dr John Fredrick Wambaugh

  23. Plasma Protein Binding Evaluations of Per- and Polyfluoroalkyl Substances for Category-Based Toxicokinetic Assessment

    Article • Chemical Research in Toxicology, May 2023, American Chemical Society (ACS)

    Dr John Fredrick Wambaugh

  24. In vitro to in vivo extrapolation and high-content imaging for simultaneous characterization of chemically induced liver steatosis and markers of hepatotoxicity

    Article • Archives of Toxicology, April 2023, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  25. A Data-Driven Approach to Estimating Occupational Inhalation Exposure Using Workplace Compliance Data

    Article • Environmental Science & Technology, March 2023, American Chemical Society (ACS)

    Dr John Fredrick Wambaugh

  26. A Machine Learning Model to Estimate Toxicokinetic Half-Lives of Per- and Polyfluoro-Alkyl Substances (PFAS) in Multiple Species

    Article • Toxics, January 2023, MDPI AG

    Dr John Fredrick Wambaugh

  27. Identifying xenobiotic metabolites with in silico prediction tools and LCMS suspect screening analysis

    Article • Frontiers in Toxicology, January 2023, Frontiers

    Dr John Fredrick Wambaugh

  28. A regression analysis using simple descriptors for multiple dermal datasets: Going from individual membranes to the full skin

    Article • Journal of Applied Toxicology, January 2023, Wiley

    Dr John Fredrick Wambaugh

  29. A geospatial modeling approach to quantifying the risk of exposure to environmental chemical mixtures via a common molecular target

    Article • The Science of The Total Environment, January 2023, Elsevier

    Dr John Fredrick Wambaugh

  30. Characterizing surface water concentrations of hundreds of organic chemicals in United States for environmental risk prioritization

    Article • Journal of Exposure Science & Environmental Epidemiology, November 2022, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  31. The chemical landscape of high-throughput new approach methodologies for exposure

    Article • Journal of Exposure Science & Environmental Epidemiology, November 2022, Springer Science + Business Media

    Dr Antony John Williams, Dr John Fredrick Wambaugh

  32. Exposure forecasting – ExpoCast – for data-poor chemicals in commerce and the environment

    Article • Journal of Exposure Science & Environmental Epidemiology, November 2022, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  33. Simulating toxicokinetic variability to identify susceptible and highly exposed populations

    Article • Journal of Exposure Science & Environmental Epidemiology, November 2022, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  34. Estimating provisional margins of exposure for data-poor chemicals using high-throughput computational methods

    Article • Frontiers in Pharmacology, October 2022, Frontiers

    Dr John Fredrick Wambaugh

  35. Evaluation of a rapid, generic human gestational dose model

    Article • Reproductive Toxicology, October 2022, Elsevier

    Dr John Fredrick Wambaugh

  36. Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk assessment

    Article • Archives of Toxicology, September 2022, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  37. Bayesian inference of chemical exposures from NHANES urine biomonitoring data

    Article • Journal of Exposure Science & Environmental Epidemiology, August 2022, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  38. Chemical screening of food-related chemicals for human fatty liver risk: Combining high content imaging of cellular responses with in vitro to in vivo extrapolation

    Article • June 2022, Cold Spring Harbor Laboratory Press

    Dr John Fredrick Wambaugh

  39. Quantitative in vitro to in vivo extrapolation for developmental toxicity potency of valproic acid analogues

    Article • Birth Defects Research, May 2022, Wiley

    Dr John Fredrick Wambaugh

  40. IVIVE: Facilitating the Use of In Vitro Toxicity Data in Risk Assessment and Decision Making

    Article • Toxics, May 2022, MDPI AG

    Dr John Fredrick Wambaugh

  41. Incorporating human exposure information in a weight of evidence approach to inform design of repeated dose animal studies

    Article • Regulatory Toxicology and Pharmacology, December 2021, Elsevier

    Dr John Fredrick Wambaugh

  42. Opportunities and challenges related to saturation of toxicokinetic processes: Implications for risk assessment

    Article • Regulatory Toxicology and Pharmacology, December 2021, Elsevier

    Dr John Fredrick Wambaugh

  43. Predicting compound amenability with liquid chromatography-mass spectrometry to improve non-targeted analysis

    Article • Fresenius Journal of Analytical Chemistry, October 2021, Springer Science + Business Media

    Dr Antony John Williams, Dr John Fredrick Wambaugh

  44. Correction to Designing QSARs for Parameters of High Throughput Toxicokinetic Models Using Open-Source Descriptors

    Article • Environmental Science & Technology, October 2021, American Chemical Society (ACS)

    Dr John Fredrick Wambaugh

  45. Chemical Characterization of Recycled Consumer Products Using Suspect Screening Analysis

    Article • Environmental Science & Technology, August 2021, American Chemical Society (ACS)

    Dr Antony John Williams, Dr John Fredrick Wambaugh

  46. Repeat-dose toxicity prediction with Generalized Read-Across (GenRA) using targeted transcriptomic data: A proof-of-concept case study

    Article • Computational Toxicology, August 2021, Elsevier

    Dr John Fredrick Wambaugh

  47. High-throughput PBTK models for in vitro to in vivo extrapolation

    Article • Expert Opinion on Drug Metabolism & Toxicology, June 2021, Taylor & Francis

    Dr John Fredrick Wambaugh

  48. Designing QSARs for Parameters of High-Throughput Toxicokinetic Models Using Open-Source Descriptors

    Article • Environmental Science & Technology, April 2021, American Chemical Society (ACS)

    Dr John Fredrick Wambaugh

  49. High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures

    Article • npj Systems Biology and Applications, January 2021, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  50. GRADE Guidelines 30: the GRADE approach to assessing the certainty of modeled evidence—An overview in the context of health decision-making

    Article • Journal of Clinical Epidemiology, January 2021, Elsevier

    Dr John Fredrick Wambaugh, Alexander Mathioudakis

  51. Using chemical structure information to develop predictive models for in vitro toxicokinetic parameters to inform high-throughput risk-assessment

    Article • Computational Toxicology, November 2020, Elsevier

    Dr John Fredrick Wambaugh

  52. PBPK model reporting template for chemical risk assessment applications

    Article • Regulatory Toxicology and Pharmacology, August 2020, Elsevier

    Dr John Fredrick Wambaugh

  53. Pharmacokinetic profile of Perfluorobutane Sulfonate and activation of hepatic nuclear receptor target genes in mice

    Article • Toxicology, August 2020, Elsevier

    Dr John Fredrick Wambaugh

  54. Correction: Development and evaluation of a high throughput inhalation model for organic chemicals

    Article • Journal of Exposure Science & Environmental Epidemiology, July 2020, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  55. Development and evaluation of a high throughput inhalation model for organic chemicals

    Article • Journal of Exposure Science & Environmental Epidemiology, June 2020, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  56. Database of pharmacokinetic time-series data and parameters for 144 environmental chemicals

    Article • Scientific Data, April 2020, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  57. High-throughput screening tools facilitate calculation of a combined exposure-bioactivity index for chemicals with endocrine activity

    Article • Environment International, April 2020, Elsevier

    Dr John Fredrick Wambaugh

  58. New Approach Methods to Evaluate Health Risks of Air Pollutants: Critical Design Considerations for In Vitro Exposure Testing

    Article • International Journal of Environmental Research and Public Health, March 2020, MDPI AG

    Dr John Fredrick Wambaugh

  59. Toxicity testing in the 21st century: progress in the past decade and future perspectives

    Article • Archives of Toxicology, December 2019, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  60. Assessing Toxicokinetic Uncertainty and Variability in Risk Prioritization

    Article • Toxicological Sciences, September 2019, Oxford University Press (OUP)

    Dr John Fredrick Wambaugh

  61. New approach methodologies for exposure science

    Article • Current Opinion in Toxicology, June 2019, Elsevier

    Dr John Fredrick Wambaugh

  62. Using the concordance of in vitro and in vivo data to evaluate extrapolation assumptions

    Article • PLOS One, May 2019, PLOS

    Dr John Fredrick Wambaugh

  63. Empirical models for anatomical and physiological changes in a human mother and fetus during pregnancy and gestation

    Article • PLOS One, May 2019, PLOS

    Dr Richard S Judson, Dr John Fredrick Wambaugh

  64. Estimating Uncertainty in the Context of New Approach Methodologies for Potential Use in Chemical Safety Evaluation

    Article • Current Opinion in Toxicology, April 2019, Elsevier

    Dr Richard S Judson, Dr John Fredrick Wambaugh

  65. Challenges in working towards an internal threshold of toxicological concern (iTTC) for use in the safety assessment of cosmetics: Discussions from the Cosmetics Europe iTTC Working Group workshop

    Article • Regulatory Toxicology and Pharmacology, April 2019, Elsevier

    Dr John Fredrick Wambaugh

  66. The next generation blueprint of computational toxicology at the U.S. Environmental Protection Agency

    Article • Toxicological Sciences, March 2019, Oxford University Press (OUP)

    Dr Antony John Williams, Dr John Fredrick Wambaugh

  67. Consensus Modeling of Median Chemical Intake for the U.S. Population Based on Predictions of Exposure Pathways

    Article • Environmental Science & Technology, December 2018, American Chemical Society (ACS)

    Dr John Fredrick Wambaugh

  68. Comment on: Dong et al. (2017) “Issues raised by the reference doses for perfluorooctonate sulfonate and perfluorooctanoic acid.”

    Article • Environment International, December 2018, Elsevier

    Dr John Fredrick Wambaugh

  69. Advancements in Life Cycle Human Exposure and Toxicity Characterization

    Article • Environmental Health Perspectives, December 2018, Environmental Health Perspectives

    Dr John Fredrick Wambaugh

  70. Empirical Models for Anatomical and Physiological Changes in a Human Mother and Fetus During Pregnancy and Gestation

    Article • October 2018, Cold Spring Harbor Laboratory Press

    Dr Richard S Judson, Dr John Fredrick Wambaugh

  71. Rapid experimental measurements of physicochemical properties to inform models and testing

    Article • The Science of The Total Environment, September 2018, Elsevier

    Dr Antony John Williams, Dr kamel mansouri, Dr John Fredrick Wambaugh

  72. Advancing internal exposure and physiologically-based toxicokinetic modeling for 21st-century risk assessments

    Article • Journal of Exposure Science & Environmental Epidemiology, August 2018, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  73. Utilizing Threshold of Toxicological Concern (TTC) with high throughput exposure predictions (HTE) as a risk-based prioritization approach for thousands of chemicals

    Article • Computational Toxicology, August 2018, Elsevier

    Dr John Fredrick Wambaugh

  74. In vitro to in vivo extrapolation for high throughput prioritization and decision making

    Article • Toxicology in Vitro, March 2018, Elsevier

    Dr John Fredrick Wambaugh, Dr Nicole Kleinstreuer

  75. Suspect Screening Analysis of Chemicals in Consumer Products

    Article • Environmental Science & Technology, February 2018, American Chemical Society (ACS)

    Andrew D McEachran, Dr John Fredrick Wambaugh, Dr Antony John Williams

  76. Defining toxicological tipping points in neuronal network development

    Article • Toxicology and Applied Pharmacology, February 2018, Elsevier

    Dr John Fredrick Wambaugh

  77. High-throughput in-silico prediction of ionization equilibria for pharmacokinetic modeling

    Article • The Science of The Total Environment, February 2018, Elsevier

    Dr John Fredrick Wambaugh, Dr kamel mansouri, Dr Antony John Williams

  78. Evaluating In Vitro-In Vivo Extrapolation of Toxicokinetics

    Article • Toxicological Sciences, January 2018, Oxford University Press (OUP)

    Dr John Fredrick Wambaugh

  79. Computational Tools for ADMET Profiling

    Article • January 2018, Wiley

    Dr John Fredrick Wambaugh, Dr Antony John Williams

  80. Integrating tools for non-targeted analysis research and chemical safety evaluations at the US EPA

    Article • Journal of Exposure Science & Environmental Epidemiology, December 2017, Nature

    Andrew D McEachran, Dr John Fredrick Wambaugh, Dr Antony John Williams

  81. The CompTox Chemistry Dashboard: a community data resource for environmental chemistry

    Article • Journal of Cheminformatics, November 2017, Springer Science + Business Media

    Dr Antony John Williams, Andrew D McEachran, Dr John Fredrick Wambaugh, Dr kamel mansouri

  82. High-throughput dietary exposure predictions for chemical migrants from food contact substances for use in chemical prioritization

    Article • Environment International, November 2017, Elsevier

    Dr John Fredrick Wambaugh

  83. Evaluation and calibration of high-throughput predictions of chemical distribution to tissues

    Article • Journal of Pharmacokinetics and Pharmacodynamics, October 2017, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  84. Identifying populations sensitive to environmental chemicals by simulating toxicokinetic variability

    Article • Environment International, September 2017, Elsevier

    Dr John Fredrick Wambaugh

  85. A Method for Identifying Prevalent Chemical Combinations in the U.S. Population

    Article • Environmental Health Perspectives, August 2017, Environmental Health Perspectives

    Dr John Fredrick Wambaugh

  86. An Intuitive Approach for Predicting Potential Human Health Risk with the Tox21 10k Library

    Article • Environmental Science & Technology, August 2017, American Chemical Society (ACS)

    Dr John Fredrick Wambaugh

  87. From the exposome to mechanistic understanding of chemical-induced adverse effects

    Article • Environment International, February 2017, Elsevier

    Dr John Fredrick Wambaugh

  88. httk: R Package for High-Throughput Toxicokinetics

    Article • Journal of Statistical Software, January 2017, Foundation for Open Access Statistic

    Dr John Fredrick Wambaugh

  89. High-throughput screening of chemicals as functional substitutes using structure-based classification models

    Article • Green Chemistry, January 2017, Royal Society of Chemistry

    Dr John Fredrick Wambaugh

  90. A Liver-Centric Multiscale Modeling Framework for Xenobiotics

    Article • PLOS One, September 2016, PLOS

    Dr John Fredrick Wambaugh

  91. Analysis of the Effects of Cell Stress and Cytotoxicity onIn VitroAssay Activity Across a Diverse Chemical and Assay Space

    Article • Toxicological Sciences, September 2016, Oxford University Press (OUP)

    Dr Nicole Kleinstreuer, Dr John Fredrick Wambaugh

  92. ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology

    Article • Chemical Research in Toxicology, July 2016, American Chemical Society (ACS)

    Dr Antony John Williams, Dr John Fredrick Wambaugh, Dr kamel mansouri, Jayaram Kancherla

  93. Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity onIn VitroAssay Activity Across a Diverse Chemical and Assay Space

    Article • Toxicological Sciences, May 2016, Oxford University Press (OUP)

    Dr Kevin M Crofton, Dr John Fredrick Wambaugh, Dr Nicole Kleinstreuer

  94. Using mass spectrometry and reference databases to identify chemicals in house dust

    Article • Environment International, March 2016, Elsevier

    Dr Antony John Williams, Dr John Fredrick Wambaugh

  95. Development of a quantitative morphological assessment of toxicant-treated zebrafish larvae using brightfield imaging and high-content analysis

    Article • Journal of Applied Toxicology, February 2016, Wiley

    Dr John Fredrick Wambaugh

  96. Characterization and prediction of chemical functions and weight fractions in consumer products

    Article • Toxicology Reports, January 2016, Elsevier

    Dr John Fredrick Wambaugh

  97. Computational Exposure Science: An Emerging Discipline to Support 21st-Century Risk Assessment

    Article • Environmental Health Perspectives, November 2015, Environmental Health Perspectives

    Dr John Fredrick Wambaugh

  98. Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing

    Article • Toxicological Sciences, August 2015, Oxford University Press (OUP)

    Dr Keith Houck, Dr John Fredrick Wambaugh

  99. Identifiability of PBPK models with applications to dimethylarsinic acid exposure

    Article • Journal of Pharmacokinetics and Pharmacodynamics, July 2015, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  100. Toxicokinetic Triage for Environmental Chemicals

    Article • Toxicological Sciences, June 2015, Oxford University Press (OUP)

    Dr John Fredrick Wambaugh

  101. Exploring consumer exposure pathways and patterns of use for chemicals in the environment

    Article • Toxicology Reports, January 2015, Elsevier

    Dr Richard S Judson, Dr John Fredrick Wambaugh

  102. Dosimetric Anchoring of Toxicological Studies

    Article • January 2015, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  103. Rapid, automated approach to estimate human exposure to over 8,000 environmental chemicals

    Article • Environmental Science & Technology, November 2014, American Chemical Society (ACS)

    Dr Richard S Judson, Dr John Fredrick Wambaugh

  104. Incorporating Population Variability and Susceptible Subpopulations into Dosimetry for High-Throughput Toxicity Testing

    Article • Toxicological Sciences, August 2014, Oxford University Press (OUP)

    Dr John Fredrick Wambaugh

  105. In Vitroand Modelling Approaches to Risk Assessment from the U.S. Environmental Protection Agency ToxCast Programme

    Article • Basic & Clinical Pharmacology & Toxicology, April 2014, Wiley

    Dr Richard S Judson, Dr Keith Houck, Dr John Fredrick Wambaugh, Dr Kevin M Crofton

  106. Development of a consumer product ingredient database for chemical exposure screening and prioritization

    Article • Food and Chemical Toxicology, March 2014, Elsevier

    Dr Richard S Judson, Dr John Fredrick Wambaugh

  107. Erratum

    Article • Toxicological Sciences, January 2014, Oxford University Press (OUP)

    Dr Richard S Judson, Dr John Fredrick Wambaugh

  108. Dosimetric Anchoring of In Vivo and In Vitro Studies for Perfluorooctanoate and Perfluorooctanesulfonate

    Article • Toxicological Sciences, September 2013, Oxford University Press (OUP)

    Dr Richard S Judson, Dr John Fredrick Wambaugh, Dr Nicole Kleinstreuer

  109. Comparison of modeling approaches to prioritize chemicals based on estimates of exposure and exposure potential

    Article • The Science of The Total Environment, August 2013, Elsevier

    Dr John Fredrick Wambaugh

  110. High-Throughput Models for Exposure-Based Chemical Prioritization in the ExpoCast Project

    Article • Environmental Science & Technology, July 2013, American Chemical Society (ACS)

    Dr Richard S Judson, Dr John Fredrick Wambaugh

  111. Relative Impact of Incorporating Pharmacokinetics on Predicting In Vivo Hazard and Mode of Action from High-Throughput In Vitro Toxicity Assays

    Article • Toxicological Sciences, January 2013, Oxford University Press (OUP)

    Dr Richard S Judson, Dr John Fredrick Wambaugh

  112. Incorporating exposure information into the toxicological prioritization index decision support framework

    Article • The Science of The Total Environment, October 2012, Elsevier

    Dr Richard S Judson, Dr John Fredrick Wambaugh

  113. Systems Toxicology from Genes to Organs

    Article • August 2012, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  114. P68—Parsimonious development of a physiologically based pharmacokinetic model for PFOA

    Article • Reproductive Toxicology, July 2012, Elsevier

    Dr John Fredrick Wambaugh

  115. Response to "Accurate Risk-Based Chemical Screening * Relies on Robust Exposure Estimates"

    Article • Toxicological Sciences, April 2012, Oxford University Press (OUP)

    Dr Richard S Judson, Dr John Fredrick Wambaugh

  116. Modeling In Vitro Cell-Based Assays Experiments

    Article • January 2012, Elsevier

    Dr Richard S Judson, Dr John Fredrick Wambaugh

  117. Physiologically Based Pharmacokinetic Model Use in Risk Assessment--Why Being Published Is Not Enough

    Article • Toxicological Sciences, November 2011, Oxford University Press (OUP)

    Dr John Fredrick Wambaugh

  118. Integration of Dosimetry, Exposure, and High-Throughput Screening Data in Chemical Toxicity Assessment

    Article • Toxicological Sciences, September 2011, Oxford University Press (OUP)

    Dr Richard S Judson, Dr John Fredrick Wambaugh

  119. Comparative pharmacokinetics of perfluorononanoic acid in rat and mouse☆

    Article • Toxicology, March 2011, Elsevier

    Dr John Fredrick Wambaugh

  120. Using Nuclear Receptor Activity to Stratify Hepatocarcinogens

    Article • PLOS One, February 2011, PLOS

    Dr Richard S Judson, Dr Keith Houck, Dr John Fredrick Wambaugh

  121. Simulating Quantitative Cellular Responses Using Asynchronous Threshold Boolean Network Ensembles

    Article • BMC Systems Biology, January 2011, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  122. Simple models for granular force networks

    Article • Physica D Nonlinear Phenomena, September 2010, Elsevier

    Dr John Fredrick Wambaugh

  123. Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening

    Article • Toxicological Sciences, July 2010, Oxford University Press (OUP)

    Dr Richard S Judson, Dr John Fredrick Wambaugh

  124. Virtual Tissues in Toxicology

    Article • Journal of Toxicology and Environmental Health Part B, June 2010, Taylor & Francis

    Dr John Fredrick Wambaugh

  125. Force networks and elasticity in granular silos

    Article • The European Physical Journal E, June 2010, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  126. Simulating Microdosimetry in a Virtual Hepatic Lobule

    Article • PLoS Computational Biology, April 2010, PLOS

    Dr John Fredrick Wambaugh

  127. Modeling single and repeated dose pharmacokinetics of PFOA in mice

    Article • Reproductive Toxicology, June 2009, Elsevier

    Dr John Fredrick Wambaugh

  128. Modeling Single and Repeated Dose Pharmacokinetics of PFOA in Mice

    Article • Toxicological Sciences, December 2008, Oxford University Press (OUP)

    Dr John Fredrick Wambaugh

  129. Comparing models for perfluorooctanoic acid pharmacokinetics using Bayesian analysis

    Article • Journal of Pharmacokinetics and Pharmacodynamics, December 2008, Springer Science + Business Media

    Dr John Fredrick Wambaugh

  130. Response to perturbations for granular flow in a hopper

    Article • Physical Review E, November 2007, American Physical Society (APS)

    Dr John Fredrick Wambaugh

  131. Shear and loading in channels: Oscillatory shearing and edge currents of superconducting vortices

    Article • April 2003, American Physical Society (APS)

    Dr John Fredrick Wambaugh

  132. Ratchet-induced segregation and transport of nonspherical grains

    Article • March 2002, American Physical Society (APS)

    Dr John Fredrick Wambaugh

  133. Superconducting Fluxon Pumps and Lenses

    Article • Physical Review Letters, December 1999, American Physical Society (APS)

    Dr John Fredrick Wambaugh

  134. The electronic design notebook: Performing medium and processing medium

    Article • The Visual Computer, July 1989, Springer Science + Business Media

    Dr John Fredrick Wambaugh