All Stories

  1. Microbiome and Gut as Partners in the Persistence of Post-Inflammatory Visceral Pain Insight into Working Mechanisms of Faecal Transplant for Therapy Advance
  2. Building a roadmap to nutrition for Healthy Ageing: a brief report on the ILSI Europe Healthy Ageing Task Force
  3. Gut microbiota dysbiosis affects intestinal sensitivity through epithelium-to-neuron signaling: novel insights from a colon organoid-based model to improve visceral pain therapy
  4. Normalizing Body Weight with a Dietary Strategy Mitigates Obesity-Accelerated Pancreatic Carcinogenesis in Mice
  5. Hormone replacement therapy and dementia risk among postmenopausal women: evidence from the UK Biobank
  6. APOE4 genotype shapes the role of dietary fibers in cognitive health through gut microbiota changes
  7. The gut microbiota in menopause: Is there a role for prebiotic and probiotic solutions?
  8. A standardised saffron extract improves subjective and objective sleep quality in healthy older adults with sleep complaints: results from the Gut-Sleep-Brain Axis randomised, double-blind, placebo-controlled pilot study
  9. The effects of inorganic nitrate and inulin co-ingestion on circulating metabolites and blood pressure in young adults: a pilot double-blind randomised crossover trial
  10. The effects of inorganic nitrate and inulin co-ingestion on circulating metabolites and blood pressure in young adults: a pilot double-blind randomised crossover trial – CORRIGENDUM
  11. The impact of single nucleotide polymorphisms on the absorption, distribution, metabolism, and excretion of dietary (poly)phenols: a critical systematic review
  12. Oral microbiome and nitric oxide biomarkers in older people with mild cognitive impairment and APOE4 genotype
  13. Menopause and Alzheimer’s disease susceptibility: Exploring the potential mechanisms
  14. Cerebrovascular damage caused by the gut microbe/host co-metabolite p -cresol sulfate is prevented by blockade of the EGF receptor
  15. (Poly)phenol-rich grape and blueberry extract prevents LPS-induced disruption of the blood-brain barrier through the modulation of the gut microbiota-derived uremic toxins
  16. (Poly)phenols and brain health – beyond their antioxidant capacity
  17. A novel Mediterranean diet-inspired supplement ameliorates cognitive, microbial, and metabolic deficits in a mouse model of low-grade inflammation
  18. Editorial: Nutrition for an aging brain
  19. Dietary (Poly)phenols and the Gut–Brain Axis in Ageing
  20. Circulatory dietary and gut-derived metabolites predict preclinical Alzheimer’s disease
  21. Do microbes play a role in Alzheimer's disease?
  22. Refined diet consumption increases neuroinflammatory signalling through bile acid dysmetabolism
  23. Dietary fiber supplementation increases Drosophila melanogaster lifespan and gut microbiota diversity
  24. Unravelling phenolic metabotypes in the frame of the COMBAT study, a randomized, controlled trial with cranberry supplementation
  25. Reply to M. Plourde and M. Stiffel
  26. Sexual dimorphism in the context of nutrition and health
  27. Role of mucin glycosylation in the gut microbiota-brain axis of core 3 O-glycan deficient mice
  28. Personality, dietary identity, mental and sleep health in vegans and vegetarians: A preliminary cross‐sectional study
  29. A combined DHA-rich fish oil and cocoa flavanols intervention does not improve cognition or brain structure in older adults with memory complaints: results from the CANN randomized, controlled parallel-design study
  30. The Influence of APOE Genotype, DHA, and Flavanol Intervention on Brain DHA and Lipidomics Profile in Aged Transgenic Mice
  31. Data from A Ketogenic Diet in Combination with Gemcitabine Increases Survival in Pancreatic Cancer KPC Mice
  32. Data from A Ketogenic Diet in Combination with Gemcitabine Increases Survival in Pancreatic Cancer KPC Mice
  33. Supplementary Table S1, Figures S1-S8 from A Ketogenic Diet in Combination with Gemcitabine Increases Survival in Pancreatic Cancer KPC Mice
  34. Supplementary Table S1, Figures S1-S8 from A Ketogenic Diet in Combination with Gemcitabine Increases Survival in Pancreatic Cancer KPC Mice
  35. Natural Products and Neuroprotection 3.0
  36. Nutrition and the Ageing Brain
  37. Correction: A Ketogenic Diet in Combination with Gemcitabine Increases Survival in Pancreatic Cancer KPC Mice
  38. Cerebrovascular damage caused by the gut microbe-derived uraemic toxinp-cresol sulfate is prevented by blockade of the epidermal growth factor receptor
  39. Wholegrain fermentation affects gut microbiota composition, phenolic acid metabolism and pancreatic beta cell function in a rodent model of type 2 diabetes
  40. Multi-nutrient interventions and cognitive ageing: are we barking up the right tree?
  41. A Ketogenic Diet in Combination with Gemcitabine Increases Survival in Pancreatic Cancer KPC Mice
  42. (-)-Epicatechin mitigates anxiety-related behavior in a mouse model of high fat diet-induced obesity
  43. The EAT–Lancet reference diet and cognitive function across the life course
  44. Systematic analysis of nutrigenomic effects of polyphenols related to cardiometabolic health in humans – Evidence from untargeted mRNA and miRNA studies
  45. Editorial: Polyphenols' action on the brain
  46. Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia
  47. Chronic Consumption of Cranberries (Vaccinium macrocarpon) for 12 Weeks Improves Episodic Memory and Regional Brain Perfusion in Healthy Older Adults: A Randomised, Placebo-Controlled, Parallel-Groups Feasibility Study
  48. The role of the mucin-glycan foraging Ruminococcus gnavus in the communication between the gut and the brain
  49. Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain
  50. DHA-Enriched Fish Oil Ameliorates Deficits in Cognition Associated with Menopause and the APOE4 Genotype in Rodents
  51. Circulating Human Serum Metabolites Derived from the Intake of a Saffron Extract (Safr’InsideTM) Protect Neurons from Oxidative Stress: Consideration for Depressive Disorders
  52. The microbiota–gut–brain axis: pathways to better brain health. Perspectives on what we know, what we need to investigate and how to put knowledge into practice
  53. The microRNA-455 Null Mouse Has Memory Deficit and Increased Anxiety, Targeting Key Genes Involved in Alzheimer’s Disease
  54. Saffron extract (Safr'Inside™) improves anxiety related behaviour in a mouse model of low-grade inflammation through the modulation of the microbiota and gut derived metabolites
  55. Cognitive Ageing: The Role of Nutrition
  56. Differential Influence of Soluble Dietary Fibres on Intestinal and Hepatic Carbohydrate Response
  57. Regulation of blood–brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide
  58. Anthocyanins Promote Learning through Modulation of Synaptic Plasticity Related Proteins in an Animal Model of Ageing
  59. Systematic Bioinformatic Analyses of Nutrigenomic Modifications by Polyphenols Associated with Cardiometabolic Health in Humans—Evidence from Targeted Nutrigenomic Studies
  60. Molecular Determinants of the Cardiometabolic Improvements of Dietary Flavanols Identified by an Integrative Analysis of Nutrigenomic Data from a Systematic Review of Animal Studies
  61. Acute Effects of Polyphenols on Human Attentional Processes: A Systematic Review and Meta-Analysis
  62. Therapeutic Opportunities for Food Supplements in Neurodegenerative Disease and Depression
  63. APOE4 genotype exacerbates the impact of menopause on cognition and synaptic plasticity in APOE‐TR mice
  64. Citrus Polyphenols in Brain Health and Disease: Current Perspectives
  65. Effects of Saffron Extract Supplementation on Mood, Well-Being, and Response to a Psychosocial Stressor in Healthy Adults: A Randomized, Double-Blind, Parallel Group, Clinical Trial
  66. Regulation of blood–brain barrier integrity and cognition by the microbiome-associated methylamines trimethylamine-N-oxide and trimethylamine
  67. Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients
  68. Nutrition and the ageing brain: Moving towards clinical applications
  69. The Effect of Long-Term Aronia melanocarpa Extract Supplementation on Cognitive Performance, Mood, and Vascular Function: A Randomized Controlled Trial in Healthy, Middle-Aged Individuals
  70. The role of diet in preventing and reducing cognitive decline
  71. (-)-Epicatechin and NADPH oxidase inhibitors prevent bile acid-induced Caco-2 monolayer permeabilization through ERK1/2 modulation
  72. Acute Intake of a Grape and Blueberry Polyphenol-Rich Extract Ameliorates Cognitive Performance in Healthy Young Adults During a Sustained Cognitive Effort
  73. Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients
  74. Natural Products and Neuroprotection
  75. Inorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humans
  76. Altered SPMs and age-associated decrease in brain DHA in APOE4 female mice
  77. APOE genotype influences the gut microbiome structure and function in humans and mice: relevance for Alzheimer’s disease pathophysiology
  78. Wine Polyphenols and Neurodegenerative Diseases: An Update on the Molecular Mechanisms Underpinning Their Protective Effects
  79. Association between Apolipoprotein E genotype and the gut microbiome composition in humans and mice
  80. The impact of cranberries on microbiome and brain in healthy ageing
  81. Polyphenols Targeting Brain Cells Longevity, Brain’s Redox Status, and Neurodegenerative Diseases
  82. Inhibition of PP2A by hesperetin may contribute to Akt and ERK1/2 activation status in cortical neurons
  83. Validation of control genes and a standardised protocol for quantifying gene expression in the livers of C57BL/6 and ApoE−/− mice
  84. The effect of APOE genotype on Alzheimer’s disease risk is influenced by sex and DHA status
  85. Impact of Flavonoids on Cellular and Molecular Mechanisms Underlying Age-Related Cognitive Decline and Neurodegeneration
  86. Do anthocyanins in purple tomatoes reduce the risk of cardiovascular disease?–Retraction
  87. Poor cognitive ageing: Vulnerabilities, mechanisms and the impact of nutritional interventions
  88. n-3 Fatty acids combined with flavan-3-ols prevent steatosis and liver injury in a murine model of NAFLD
  89. The Cognitive Ageing, Nutrition and Neurogenesis (CANN) trial: Design and progress
  90. Nutrition for the ageing brain: Towards evidence for an optimal diet
  91. The effect of dietary fish oil on weight gain and insulin sensitivity is dependent on APOE genotype in humanized targeted replacement mice
  92. Polyphenols and brain health
  93. Neuroprotective Effects of Polyphenols in Aging and Age-Related Neurological Disorders
  94. High-flavonoid intake induces cognitive improvements linked to changes in serum brain-derived neurotrophic factor: Two randomised, controlled trials
  95. Differential effects of EPA versus DHA on postprandial vascular function and the plasma oxylipin profile in men
  96. A Transgenic Camelina sativa Seed Oil Effectively Replaces Fish Oil as a Dietary Source of Eicosapentaenoic Acid in Mice
  97. Neuroprotective Effects Associated with Wine and Its Phenolic Constituents
  98. Polyphenols and non-alcoholic fatty liver disease: impact and mechanisms
  99. Neuroinflammatory processes in cognitive disorders: Is there a role for flavonoids and n-3 polyunsaturated fatty acids in counteracting their detrimental effects?
  100. Low-grade inflammation, diet composition and health: current research evidence and its translation
  101. Anthocyanins do not influence long-chain n-3 fatty acid status: studies in cells, rodents and humans
  102. Dietary Levels of Pure Flavonoids Improve Spatial Memory Performance and Increase Hippocampal Brain-Derived Neurotrophic Factor
  103. Do anthocyanins in purple tomatoes reduce the risk of cardiovascular disease?
  104. Dietary Polyphenols and Their Effects on Cell Biochemistry and Pathophysiology 2014
  105. The neurotoxicity of 5-S-cysteinyldopamine is mediated by the early activation of ERK1/2 followed by the subsequent activation of ASK1/JNK1/2 pro-apoptotic signalling
  106. Bioavailability, bioactivity and impact on health of dietary flavonoids and related compounds: an update
  107. Polyphénols et neuroprotection : où en sommes-nous aujourd’hui ?
  108. SULFORAPHANE PROTECTS CORTICAL NEURONS AGAINST ENDOGENOUS NEUROTOXINS IN A MODEL OF PARKINSON'S DISEASE
  109. A role for hippocampal PSA-NCAM and NMDA-NR2B receptor function in flavonoid-induced spatial memory improvements in young rats
  110. The impact of fish‐oil fatty acids on postprandial vascular reactivity (959.22)
  111. Plant Polyphenols as Dietary Modulators of Brain Functions
  112. The Impact of Gastrointestinal Modifications, Blood-Brain Barrier Transport, and Intracellular Metabolism on Polyphenol Bioavailability
  113. Redox Signaling in Degenerative Diseases: From Molecular Mechanisms to Health Implications
  114. Dietary Polyphenols and Their Effects on Cell Biochemistry and Pathophysiology 2013
  115. The impact of Champagne wine consumption on vascular and cognitive functions
  116. Effect of flavonoids on learning, memory and neurocognitive performance: relevance and potential implications for Alzheimer's disease pathophysiology
  117. Phenolic Acid Intake, DeliveredViaModerate Champagne Wine Consumption, Improves Spatial Working MemoryViathe Modulation of Hippocampal and Cortical Protein Expression/Activation
  118. Dietary Levels of Pure Flavonoids Improve Spatial Memory Performance and Increase Hippocampal Brain-Derived Neurotrophic Factor
  119. Effect of Cultivar Type and Ripening on the Polyphenol Content of Date Palm Fruit
  120. Potential Neuroprotective Actions of Dietary Flavonoids
  121. The effect of anthocyanin consumption on blood and tissue levels of fatty acids in animals and humans
  122. The impact of polyphenols and flavonoids on memory, learning and neuro-cognitive performance
  123. Blueberry supplementation induces spatial memory improvements and region-specific regulation of hippocampal BDNF mRNA expression in young rats
  124. Flavonoids and Neuroinflammation
  125. Polyphenols
  126. Neuroinflammation: Modulation by flavonoids and mechanisms of action
  127. Regulation of NF-κB activity in astrocytes: effects of flavonoids at dietary-relevant concentrations
  128. Inhibition of colon adenocarcinoma cell proliferation by flavonols is linked to a G2/M cell cycle block and reduction in cyclin D1 expression
  129. Dietary Polyphenols and Their Effects on Cell Biochemistry and Pathophysiology
  130. Dietary Polyphenols as Modulators of Brain Functions: Biological Actions and Molecular Mechanisms Underpinning Their Beneficial Effects
  131. Neuroinflammation and the APOε genotype: Implications for Alzheimer's disease and modulation by dietary flavonoids and n-3 polyunsaturated fatty acids
  132. Potential Health Effects of Champagne Wine Consumption
  133. Absorption and metabolism of olive oil secoiridoids in the small intestine
  134. Neuroprotective actions of astaxanthin in cultured cortical neurones
  135. The effect of ripening on the polyphenol profile of commonly consumed varieties of date palm fruits
  136. Assessment of the anthocyanidin content of common fruits and development of a test diet rich in a range of anthocyanins
  137. Polyphenols and Human Health: Prevention of Disease and Mechanisms of Action
  138. Caffeic acid, tyrosol and p-coumaric acid are potent inhibitors of 5-S-cysteinyl-dopamine induced neurotoxicity
  139. Sulforaphane protects cortical neurons against 5-S-cysteinyl-dopamine-induced toxicity through the activation of ERK1/2, Nrf-2 and the upregulation of detoxification enzymes
  140. Phytochemicals from beer: identification, antioxidant activity, absorption and bioactivity
  141. The inhibitory effects of berry-derived flavonoids against neurodegenerative processes
  142. Involvement of ERK, Akt and JNK signalling in H2O2-induced cell injury and protection by hydroxytyrosol and its metabolite homovanillic alcohol
  143. Flavonoids and cognition: The molecular mechanisms underlying their behavioural effects
  144. Moderate Champagne consumption promotes an acute improvement in acute endothelial-independent vascular function in healthy human volunteers
  145. Dietary Flavonoids as Neuroprotective Agents
  146. The impact of flavonoids on spatial memory in rodents: from behaviour to underlying hippocampal mechanisms
  147. Hydroxytyrosol inhibits the proliferation of human colon adenocarcinoma cells through inhibition of ERK1/2 and cyclin D1
  148. The citrus flavanone naringenin inhibits inflammatory signalling in glial cells and protects against neuroinflammatory injury
  149. The neuroprotective potential of flavonoids: a multiplicity of effects
  150. Glial metabolism of quercetin reduces its neurotoxic potential
  151. Peroxynitrite induced formation of the neurotoxins 5-S-cysteinyl-dopamine and DHBT-1: Implications for Parkinson’s disease and protection by polyphenols
  152. Blueberry-induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels
  153. Substrate specificity of human glutamine transaminase K as an aminotransferase and as a cysteine S-conjugate β-lyase
  154. Inhibition of cellular proliferation by the genistein metabolite 5,7,3′,4′-tetrahydroxyisoflavone is mediated by DNA damage and activation of the ATR signalling pathway
  155. Activation of pro-survival Akt and ERK1/2 signalling pathways underlie the anti-apoptotic effects of flavanones in cortical neurons
  156. Inhibition of the formation of the neurotoxin 5-S-cysteinyl-dopamine by polyphenols
  157. Inhibition of p38/CREB phosphorylation and COX-2 expression by olive oil polyphenols underlies their anti-proliferative effects
  158. Neuroinflammation and its Modulation by Flavonoids
  159. Champagne Wine Polyphenols Protect Primary Cortical Neurons against Peroxynitrite-Induced Injury
  160. The reaction of flavonoid metabolites with peroxynitrite
  161. The intracellular genistein metabolite 5,7,3′,4′-tetrahydroxyisoflavone mediates G2-M cell cycle arrest in cancer cells via modulation of the p38 signaling pathway
  162. Activation of glutathione peroxidase via Nrf1 mediates genistein’s protection against oxidative endothelial cell injury
  163. The beneficial effects of dietary flavonoids: sources, bioavailability and biological functions.
  164. Gut microbe-derived metabolites regulate blood-brain barrier integrity
  165. Young to aged fecal microbiota transfer reverses hallmarks of the aging gut, eye, and brain