All Stories

  1. G protein-coupled receptor digital twins for precision and personalized medicine

    Article • Computational and Structural Biotechnology Journal, January 2025, Elsevier

    Professor Stuart Maudsley

  2. USP20 deletion promotes eccentric cardiac remodeling in response to pressure overload and increases mortality

    Article • AJP Heart and Circulatory Physiology, November 2024, American Physiological Society

    Professor Stuart Maudsley

  3. Editorial: GPCRs: signal transduction

    Article • Frontiers in Molecular Biosciences, April 2024, Frontiers

    Professor Stuart Maudsley

  4. Editorial: Macromolecular interactions in signaling pathways: from classical approaches to virtual reality

    Article • Frontiers in Endocrinology, February 2024, Frontiers

    Professor Stuart Maudsley

  5. Chronic dehydration induces injury pathways in rats, but does not mimic histopathology of chronic interstitial nephritis in agricultural communities

    Article • Scientific Reports, October 2023, Springer Science + Business Media

    Professor Stuart Maudsley

  6. GPR19 Coordinates Multiple Molecular Aspects of Stress Responses Associated with the Aging Process

    Article • International Journal of Molecular Sciences, May 2023, MDPI AG

    Professor Stuart Maudsley

  7. The oDGal Mouse: A Novel, Physiologically Relevant Rodent Model of Sporadic Alzheimer’s Disease

    Article • International Journal of Molecular Sciences, April 2023, MDPI AG

    Professor Stuart Maudsley

  8. A Proteomic Screen to Unravel the Molecular Pathways Associated with Warfarin-Induced or TNAP-Inhibited Arterial Calcification in Rats

    Article • International Journal of Molecular Sciences, February 2023, MDPI AG

    Professor Stuart Maudsley

  9. Intersection of the Orphan G Protein-Coupled Receptor, GPR19, with the Aging Process

    Article • International Journal of Molecular Sciences, November 2022, MDPI AG

    Professor Stuart Maudsley

  10. Progression of established non-diabetic chronic kidney disease is halted by metformin treatment in rats

    Article • Kidney International, May 2022, Elsevier

    Professor Stuart Maudsley

  11. The Relaxin-3 Receptor, RXFP3, Is a Modulator of Aging-Related Disease

    Article • International Journal of Molecular Sciences, April 2022, MDPI AG

    Professor Stuart Maudsley

  12. Making Biomedical Sciences publications more accessible for machines

    Article • Medicine Health Care and Philosophy, January 2022, Springer Science + Business Media

    Professor Stuart Maudsley

  13. Systems Pharmacology: Enabling Multidimensional Therapeutics

    Article • January 2022, Elsevier

    Professor Stuart Maudsley

  14. GPCRs Are Optimal Regulators of Complex Biological Systems and Orchestrate the Interface between Health and Disease

    Article • International Journal of Molecular Sciences, December 2021, MDPI AG

    Professor Stuart Maudsley

  15. Endothelial Contribution to Warfarin-Induced Arterial Media Calcification in Mice

    Article • International Journal of Molecular Sciences, October 2021, MDPI AG

    Professor Stuart Maudsley

  16. Aging-related modifications to G protein-coupled receptor signaling diversity

    Article • Pharmacology & Therapeutics, July 2021, Elsevier

    Professor Stuart Maudsley

  17. The TRY‐motif in the Relaxin Family Peptide Receptor 3 (RXFP3) functions as a Molecular Switch Between DNA Damage Response and Cell Cycle Control

    Article • The FASEB Journal, May 2021, Wiley

    Professor Stuart Maudsley

  18. Effects of Detergent on α-Synuclein Structure: A Native MS-Ion Mobility Study

    Article • International Journal of Molecular Sciences, October 2020, MDPI AG

    Professor Stuart Maudsley

  19. Metal ions shape α-synuclein

    Article • Scientific Reports, October 2020, Springer Science + Business Media

    Professor Stuart Maudsley

  20. P0099CALCINEURIN INHIBITION, BUT NOT DEHYDRATION, IN RATS MIMICS HUMAN RENAL HISTOPATHOLOGY OF PATIENTS WITH CHRONIC INTERSTITIAL NEPHRITIS IN AGRICULTURAL COMMUNITIES (CINAC)

    Article • Nephrology Dialysis Transplantation, June 2020, Oxford University Press (OUP)

    Professor Stuart Maudsley

  21. Profiling of the Peripheral Blood Mononuclear Cell Proteome in Schizophrenia and Mood Disorders for the Discovery of Discriminatory Biomarkers: A Proof-of-Concept Study

    Article • Neuropsychobiology, January 2020, Karger Publishers

    Professor Stuart Maudsley

  22. Multisystem proteinopathy due to a homozygous p.Arg159His VCP mutation

    Article • Neurology, December 2019, Wolters Kluwer Health

    Professor Stuart Maudsley

  23. High-dimensionality Data Analysis of Pharmacological Systems Associated with Complex Diseases

    Article • Pharmacological Reviews, December 2019, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Stuart Maudsley

  24. The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage

    Article • Aging, December 2019, Impact Journals, LLC

    Professor Stuart Maudsley

  25. Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic GIT2 in aging trajectories

    Article • Mechanisms of Ageing and Development, December 2019, Elsevier

    Professor Stuart Maudsley

  26. Sclerostin as Regulatory Molecule in Vascular Media Calcification and the Bone–Vascular Axis

    Article • Toxins, July 2019, MDPI AG

    Professor Stuart Maudsley

  27. Indoxyl Sulfate and p-Cresyl Sulfate Promote Vascular Calcification and Associate with Glucose Intolerance

    Article • Journal of the American Society of Nephrology, April 2019, American Society of Nephrology

    Professor Stuart Maudsley

  28. Image-guided phenotyping of ovariectomized mice: altered functional connectivity, cognition, myelination, and dopaminergic functionality

    Article • Neurobiology of Aging, February 2019, Elsevier

    Drs Jaana van Gastel, Professor Stuart Maudsley

  29. G Protein-Coupled Receptor Systems and Their Role in Cellular Senescence

    Article • Computational and Structural Biotechnology Journal, January 2019, Elsevier

    Professor Stuart Maudsley

  30. Enhanced Molecular Appreciation of Psychiatric Disorders Through High-Dimensionality Data Acquisition and Analytics

    Article • January 2019, Springer Science + Business Media

    Professor Stuart Maudsley

  31. GRK5 – A Functional Bridge Between Cardiovascular and Neurodegenerative Disorders

    Article • Frontiers in Pharmacology, December 2018, Frontiers

    Professor Stuart Maudsley

  32. β-Arrestin Based Receptor Signaling Paradigms: Potential Therapeutic Targets for Complex Age-Related Disorders

    Article • Frontiers in Pharmacology, November 2018, Frontiers

    Drs Jaana van Gastel, Professor Stuart Maudsley

  33. Aging and drug discovery

    Article • Aging, November 2018, Impact Journals, LLC

    Professor Stuart Maudsley

  34. G Protein-Coupled Receptor Systems as Crucial Regulators of DNA Damage Response Processes

    Article • International Journal of Molecular Sciences, September 2018, MDPI AG

    Drs Jaana van Gastel, Professor Stuart Maudsley

  35. GIT2—A keystone in ageing and age-related disease

    Article • Ageing Research Reviews, May 2018, Elsevier

    Drs Jaana van Gastel, Professor Stuart Maudsley

  36. Intelligent and effective informatic deconvolution of “Big Data” and its future impact on the quantitative nature of neurodegenerative disease therapy

    Article • Alzheimer s & Dementia, March 2018, Elsevier

    Professor Stuart Maudsley, Professor Stuart Maudsley

  37. Poor cognitive ageing: Vulnerabilities, mechanisms and the impact of nutritional interventions

    Article • Ageing Research Reviews, March 2018, Elsevier

    Dr David Vauzour, Professor Stuart Maudsley

  38. PFN2 and GAMT as common molecular determinants of axonal Charcot-Marie-Tooth disease

    Article • Journal of Neurology Neurosurgery & Psychiatry, February 2018, BMJ

    Dr Bernard L Schneider, Professor Stuart Maudsley

  39. Translating in vitro ligand bias into in vivo efficacy

    Article • Cellular Signalling, January 2018, Elsevier

    Professor Stuart Maudsley, Professor Stuart Maudsley

  40. Inhibitory actions of the NRG-1/ErbB4 pathway in macrophages during tissue fibrosis in the heart, skin, and lung

    Article • AJP Heart and Circulatory Physiology, November 2017, American Physiological Society

    Professor Stuart Maudsley

  41. Correction for Lu et al., “Nuclear GIT2 Is an ATM Substrate and Promotes DNA Repair”

    Article • Molecular and Cellular Biology, August 2017, ASM Journals

    Professor Stuart Maudsley

  42. Altered learning, memory, and social behavior in type 1 taste receptor subunit 3 knock-out mice are associated with neuronal dysfunction

    Article • Journal of Biological Chemistry, July 2017, Elsevier

    Professor Stuart Maudsley

  43. Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption

    Article • Aging, March 2017, Impact Journals, LLC

    Drs Jaana van Gastel, Professor Stuart Maudsley

  44. Development of Precision Small-Molecule Proneurotrophic Therapies for Neurodegenerative Diseases

    Article • January 2017, Elsevier

    Drs Jaana van Gastel, Professor Stuart Maudsley

  45. Big data to smart data in Alzheimer's disease: The brain health modeling initiative to foster actionable knowledge

    Article • Alzheimer s & Dementia, May 2016, Wiley

    Professor Stuart Maudsley

  46. Alternative Splicing of Neuronal Differentiation Factor TRF2 Regulated by HNRNPH1/H2

    Article • Cell Reports, May 2016, Elsevier

    Professor Stuart Maudsley

  47. GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging

    Article • Frontiers in Endocrinology, January 2016, Frontiers

    Professor Stuart Maudsley

  48. Informatic deconvolution of biased GPCR signaling mechanisms from in vivo pharmacological experimentation

    Article • Methods, January 2016, Elsevier

    Drs Jaana van Gastel, Professor Stuart Maudsley

  49. Hippocampal Transcriptomic and Proteomic Alterations in the BTBR Mouse Model of Autism Spectrum Disorder

    Article • Frontiers in Physiology, November 2015, Frontiers

    Professor Stuart Maudsley

  50. Investigating the role of filamin C in Belgian patients with frontotemporal dementia linked to GRN deficiency in FTLD-TDP brains

    Article • Acta Neuropathologica Communications, November 2015, Springer Science + Business Media

    Professor Stuart Maudsley

  51. Human Obesity Associated with an Intronic SNP in the Brain-Derived Neurotrophic Factor Locus

    Article • Cell Reports, November 2015, Elsevier

    Professor Stuart Maudsley

  52. Recessive mutations inSLC13A5result in a loss of citrate transport and cause neonatal epilepsy, developmental delay and teeth hypoplasia

    Article • Brain, September 2015, Oxford University Press (OUP)

    Professor Stuart Maudsley

  53. Fulfilling the Promise of "Biased" G Protein–Coupled Receptor Agonism

    Article • Molecular Pharmacology, July 2015, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Stuart Maudsley

  54. Delineation of a Conserved Arrestin-Biased Signaling Repertoire In Vivo

    Article • Molecular Pharmacology, January 2015, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Stuart Maudsley

  55. Nuclear GIT2 Is an ATM Substrate and Promotes DNA Repair

    Article • Molecular and Cellular Biology, January 2015, ASM Journals

    Professor Stuart Maudsley

  56. Amitriptyline Improves Motor Function via Enhanced Neurotrophin Signaling and Mitochondrial Functions in the Murine N171-82Q Huntington Disease Model

    Article • Journal of Biological Chemistry, January 2015, Elsevier

    Professor Stuart Maudsley

  57. Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice

    Article • Journal of Experimental Medicine, November 2014, Rockefeller University Press

    Professor Stuart Maudsley

  58. Systems-Level G Protein-Coupled Receptor Therapy Across a Neurodegenerative Continuum by the GLP-1 Receptor System

    Article • Frontiers in Endocrinology, September 2014, Frontiers

    Professor Stuart Maudsley

  59. The effects of aging on the BTBR mouse model of autism spectrum disorder

    Article • Frontiers in Aging Neuroscience, September 2014, Frontiers

    Professor Stuart Maudsley

  60. Resveratrol Prevents High Fat/Sucrose Diet-Induced Central Arterial Wall Inflammation and Stiffening in Nonhuman Primates

    Article • Cell Metabolism, July 2014, Elsevier

    Professor Stuart Maudsley

  61. Metabolic and hormonal signatures in pre-manifest and manifest Huntington's disease patients

    Article • Frontiers in Physiology, June 2014, Frontiers

    Professor Stuart Maudsley

  62. Pharmacophore model of the quercetin binding site of the SIRT6 protein

    Article • Journal of Molecular Graphics and Modelling, April 2014, Elsevier

    Professor Stuart Maudsley

  63. Toll-like receptors 2 and 4 modulate autonomic control of heart rate and energy metabolism

    Article • Brain Behavior and Immunity, February 2014, Elsevier

    Dr. Eitan Okun, Professor Stuart Maudsley

  64. Higher TNF-α, IGF-1, and leptin levels are found in tasters than non-tasters

    Article • Frontiers in Endocrinology, January 2014, Frontiers

    Dr Lea Dijksman, Professor Stuart Maudsley

  65. What Is the Role of Metabolic Hormones in Taste Buds of the Tongue

    Article • January 2014, Karger Publishers

    Professor Stuart Maudsley

  66. Altered Lipid and Salt Taste Responsivity in Ghrelin and GOAT Null Mice

    Article • PLOS One, October 2013, PLOS

    Professor Stuart Maudsley

  67. Longitudinal Analysis of Calorie Restriction on Rat Taste Bud Morphology and Expression of Sweet Taste Modulators

    Article • The Journals of Gerontology Series A, September 2013, Oxford University Press (OUP)

    Professor Stuart Maudsley

  68. Long-Term Artificial Sweetener Acesulfame Potassium Treatment Alters Neurometabolic Functions in C57BL/6J Mice

    Article • PLOS One, August 2013, PLOS

    Professor Stuart Maudsley

  69. Textrous!: Extracting Semantic Textual Meaning from Gene Sets

    Article • PLOS One, April 2013, PLOS

    Professor Stuart Maudsley

  70. The effect of intermittent energy and carbohydrate restrictionv. daily energy restriction on weight loss and metabolic disease risk markers in overweight women

    Article • British Journal Of Nutrition, April 2013, Cambridge University Press

    Professor Stuart Maudsley

  71. β-Arrestin-Selective G Protein-Coupled Receptor Agonists Engender Unique Biological Efficacy in Vivo

    Article • Molecular Endocrinology, February 2013, Endocrine Society

    Professor Stuart Maudsley

  72. VennPlex–A Novel Venn Diagram Program for Comparing and Visualizing Datasets with Differentially Regulated Datapoints

    Article • PLOS One, January 2013, PLOS

    Professor Stuart Maudsley

  73. The role of Thyrotropin Releasing Hormone in aging and neurodegenerative diseases

    Article • American Journal of Alzheimer’s Disease, January 2013, Columbia International Publishing

    Professor Stuart Maudsley, Professor Stuart Maudsley

  74. Systems Analysis of Arrestin Pathway Functions

    Article • January 2013, Elsevier

    Professor Stuart Maudsley, Professor Stuart Maudsley

  75. Plurigon: three dimensional visualization and classification of high-dimensionality data

    Article • Frontiers in Physiology, January 2013, Frontiers

    Professor Stuart Maudsley

  76. BRET Biosensor Analysis of Receptor Tyrosine Kinase Functionality

    Article • Frontiers in Endocrinology, January 2013, Frontiers

    Professor Stuart Maudsley

  77. Effective use of latent semantic indexing and computational linguistics in biological and biomedical applications

    Article • Frontiers in Physiology, January 2013, Frontiers

    Professor Stuart Maudsley

  78. Pancreas++: Automated Quantification of Pancreatic Islet Cells in Microscopy Images

    Article • Frontiers in Physiology, January 2013, Frontiers

    Professor Stuart Maudsley

  79. Altered Hypothalamic Protein Expression in a Rat Model of Huntington's Disease

    Article • PLOS One, October 2012, PLOS

    Professor Stuart Maudsley

  80. Euglycemic Agent-mediated Hypothalamic Transcriptomic Manipulation in the N171–82Q Model of Huntington Disease Is Related to Their Physiological Efficacy

    Article • Journal of Biological Chemistry, September 2012, Elsevier

    Professor Stuart Maudsley

  81. The effects of the ketogenic diet on behavior and cognition

    Article • Epilepsy Research, July 2012, Elsevier

    Professor Stuart Maudsley

  82. Editorial (Hot Topic: G Protein-Coupled Receptor Biased Agonism: Development Towards Future Selective Therapeutics)

    Article • Mini-Reviews in Medicinal Chemistry, June 2012, Bentham Science Publishers

    Professor Stuart Maudsley

  83. Functional Signaling Biases in G Protein-Coupled Receptors: Game Theory and Receptor Dynamics

    Article • Mini-Reviews in Medicinal Chemistry, June 2012, Bentham Science Publishers

    Professor Stuart Maudsley

  84. Precursor ion exclusion for enhanced identification of plasma biomarkers

    Article • PROTEOMICS - CLINICAL APPLICATIONS, June 2012, Wiley

    Professor Stuart Maudsley, Professor Stuart Maudsley

  85. Effective correction of experimental errors in quantitative proteomics using stable isotope labeling by amino acids in cell culture (SILAC)

    Article • Journal of Proteomics, June 2012, Elsevier

    Professor Stuart Maudsley

  86. GIT2 Acts as a Potential Keystone Protein in Functional Hypothalamic Networks Associated with Age-Related Phenotypic Changes in Rats

    Article • PLOS One, May 2012, PLOS

    Professor Stuart Maudsley

  87. VENNTURE–A Novel Venn Diagram Investigational Tool for Multiple Pharmacological Dataset Analysis

    Article • PLOS One, May 2012, PLOS

    Professor Stuart Maudsley

  88. Growth Inhibition by miR-519 via Multiple p21-Inducing Pathways

    Article • Molecular and Cellular Biology, April 2012, ASM Journals

    Professor Stuart Maudsley

  89. Stromal factors SDF1α, sFRP1, and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells

    Article • Journal of Neuroscience Research, April 2012, Wiley

    Professor Stuart Maudsley

  90. Plasma BDNF Is Associated with Age-Related White Matter Atrophy but Not with Cognitive Function in Older, Non-Demented Adults

    Article • PLOS One, April 2012, PLOS

    Professor Stuart Maudsley

  91. Discovery- and target-based protein quantification using iTRAQ and pulsed Q collision induced dissociation (PQD)

    Article • Journal of Proteomics, April 2012, Elsevier

    Professor Stuart Maudsley

  92. Metabolic Dysfunction in Alzheimers Disease and Related Neurodegenerative Disorders

    Article • Current Alzheimer Research, January 2012, Bentham Science Publishers

    Professor Stuart Maudsley, Professor Stuart Maudsley

  93. Editorial [Hot Topic: Progressive and Unconventional Pharmacotherapeutic Approaches to Alzheimers Disease Therapy (Guest Editors: Stuart Maudsley & Wayne Chadwick)]

    Article • Current Alzheimer Research, January 2012, Bentham Science Publishers

    Professor Stuart Maudsley, Professor Stuart Maudsley

  94. Anti-Inflammatory Effects of Physical Activity in Relationship to Improved Cognitive Status in Humans and Mouse Models of Alzheimers Disease

    Article • Current Alzheimer Research, January 2012, Bentham Science Publishers

    Professor Stuart Maudsley

  95. Therapeutic Targeting of the Endoplasmic Reticulum in Alzheimers Disease

    Article • Current Alzheimer Research, January 2012, Bentham Science Publishers

    Professor Stuart Maudsley

  96. Metabolic Context Regulates Distinct Hypothalamic Transcriptional Responses to Antiaging Interventions

    Article • International Journal of Endocrinology, January 2012, Wiley

    Professor Stuart Maudsley

  97. Aging and Bone Health in Individuals with Developmental Disabilities

    Article • International Journal of Endocrinology, January 2012, Wiley

    Professor Stuart Maudsley

  98. Central Role of the EGF Receptor in Neurometabolic Aging

    Article • International Journal of Endocrinology, January 2012, Wiley

    Professor Stuart Maudsley

  99. Repetitive Peroxide Exposure Reveals Pleiotropic Mitogen-Activated Protein Kinase Signaling Mechanisms

    Article • Journal of Signal Transduction, December 2011, Wiley

    Professor Stuart Maudsley

  100. Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets

    Article • Nature Medicine, December 2011, Springer Science + Business Media

    Professor Stuart Maudsley

  101. Age-Related Changes in Mouse Taste Bud Morphology, Hormone Expression, and Taste Responsivity

    Article • The Journals of Gerontology Series A, November 2011, Oxford University Press (OUP)

    Professor Stuart Maudsley

  102. To Be or Not To Be—Obese

    Article • Endocrinology, October 2011, Endocrine Society

    Professor Stuart Maudsley, Professor Stuart Maudsley

  103. Identification of Proteins and Phosphoproteins Using Pulsed Q Collision Induced Dissociation (PQD)

    Article • Journal of the American Society for Mass Spectrometry, July 2011, American Chemical Society (ACS)

    Professor Stuart Maudsley

  104. Regulation of Caenorhabditis elegans vitellogenesis by DAF-2/IIS through separable transcriptional and posttranscriptional mechanisms

    Article • BMC Physiology, July 2011, Springer Science + Business Media

    Professor Stuart Maudsley

  105. Cortical gene transcription response patterns to water maze training in aged mice

    Article • BMC Neuroscience, June 2011, Springer Science + Business Media

    Professor Stuart Maudsley

  106. Amitriptyline-Mediated Cognitive Enhancement in Aged 3×Tg Alzheimer's Disease Mice Is Associated with Neurogenesis and Neurotrophic Activity

    Article • PLOS One, June 2011, PLOS

    Professor Stuart Maudsley

  107. Multiple Oxygen Tension Environments Reveal Diverse Patterns of Transcriptional Regulation in Primary Astrocytes

    Article • PLOS One, June 2011, PLOS

    Professor Stuart Maudsley

  108. Rapid and enhanced proteolytic digestion using electric-field-oriented enzyme reactor

    Article • Journal of Proteomics, June 2011, Elsevier

    Professor Stuart Maudsley

  109. Cannabinoids Inhibit Insulin Receptor Signaling in Pancreatic β-Cells

    Article • Diabetes, March 2011, American Diabetes Association

    Professor Stuart Maudsley

  110. Discontinuous pH gradient-mediated separation of TiO2-enriched phosphopeptides

    Article • Analytical Biochemistry, February 2011, Elsevier

    Professor Stuart Maudsley, Professor Stuart Maudsley

  111. Bioinformatic Approaches to Metabolic Pathways Analysis

    Article • January 2011, Springer Science + Business Media

    Professor Stuart Maudsley

  112. Minimal Peroxide Exposure of Neuronal Cells Induces Multifaceted Adaptive Responses

    Article • PLOS One, December 2010, PLOS

    Professor Stuart Maudsley

  113. Editorial [Hot topic: New Frontiers in G Protein-Coupled Receptor Regulation of Neurological Disorders (Guest Editor: Stuart Maudsley)]

    Article • CNS & Neurological Disorders - Drug Targets, November 2010, Bentham Science Publishers

    Professor Stuart Maudsley, Professor Stuart Maudsley

  114. Ghrelin Receptor Signaling: A Promising Therapeutic Target for Metabolic Syndrome and Cognitive Dysfunction

    Article • CNS & Neurological Disorders - Drug Targets, November 2010, Bentham Science Publishers

    Professor Stuart Maudsley

  115. The Mammalian Tachykinin Ligand-Receptor System: An Emerging Target for Central Neurological Disorders

    Article • CNS & Neurological Disorders - Drug Targets, November 2010, Bentham Science Publishers

    Professor Stuart Maudsley

  116. Gonadotropin-Releasing Hormone Receptor System: Modulatory Role in Aging and Neurodegeneration

    Article • CNS & Neurological Disorders - Drug Targets, November 2010, Bentham Science Publishers

    Professor Stuart Maudsley

  117. Therapeutic Potential of Vasoactive Intestinal Peptide and its Receptors in Neurological Disorders

    Article • CNS & Neurological Disorders - Drug Targets, November 2010, Bentham Science Publishers

    Professor Stuart Maudsley

  118. Hippocampal gene expression patterns underlying the enhancement of memory by running in aged mice

    Article • Neurobiology of Aging, November 2010, Elsevier

    Professor Stuart Maudsley

  119. The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women

    Article • International Journal of Obesity, October 2010, Springer Science + Business Media

    Professor Stuart Maudsley

  120. Ghrelin Is Produced in Taste Cells and Ghrelin Receptor Null Mice Show Reduced Taste Responsivity to Salty (NaCl) and Sour (Citric Acid) Tastants

    Article • PLOS One, September 2010, PLOS

    Professor Stuart Maudsley

  121. Plasma BDNF concentration, Val66Met genetic variant and depression‐related personality traits

    Article • Genes Brain & Behavior, July 2010, Wiley

    Professor Stuart Maudsley

  122. Transferrin Fusion Technology: A Novel Approach to Prolonging Biological Half-Life of Insulinotropic Peptides

    Article • Journal of Pharmacology and Experimental Therapeutics, May 2010, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Stuart Maudsley

  123. Circulating Brain-Derived Neurotrophic Factor and Indices of Metabolic and Cardiovascular Health: Data from the Baltimore Longitudinal Study of Aging

    Article • PLOS One, April 2010, PLOS

    Professor Stuart Maudsley

  124. “Control” laboratory rodents are metabolically morbid: Why it matters

    Article • Proceedings of the National Academy of Sciences, March 2010, Proceedings of the National Academy of Sciences

    Professor Stuart Maudsley

  125. Vasoactive Intestinal Peptide–Null Mice Demonstrate Enhanced Sweet Taste Preference, Dysglycemia, and Reduced Taste Bud Leptin Receptor Expression

    Article • Diabetes, February 2010, American Diabetes Association

    Professor Stuart Maudsley

  126. Complex and Multidimensional Lipid Raft Alterations in a Murine Model of Alzheimer's Disease

    Article • International Journal of Alzheimer s Disease, January 2010, Wiley

    Professor Stuart Maudsley

  127. Chemical modification of Class II G protein-coupled receptor ligands: Frontiers in the development of peptide analogs as neuroendocrine pharmacological therapies

    Article • Pharmacology & Therapeutics, January 2010, Elsevier

    Professor Stuart Maudsley

  128. Pharmacomimetics of Exercise: Novel Approaches for Hippocampally- Targeted Neuroprotective Agents

    Article • Current Medicinal Chemistry, December 2009, Bentham Science Publishers

    Professor Stuart Maudsley

  129. The Devil is in the Dose: Complexity of Receptor Systems and Responses

    Article • October 2009, Springer Science + Business Media

    Professor Stuart Maudsley, Professor Stuart Maudsley

  130. Allosteric Modulators of G Protein-Coupled Receptors: Future Therapeutics for Complex Physiological Disorders

    Article • Journal of Pharmacology and Experimental Therapeutics, August 2009, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Stuart Maudsley

  131. Modulation of Taste Sensitivity by GLP‐1 Signaling in Taste Buds

    Article • Annals of the New York Academy of Sciences, July 2009, Wiley

    Professor Stuart Maudsley

  132. Neonatal Estrogenic Effects upon the Male Rat Pituitary: Early Gonadotrophin Attenuation Precedes Long-term Recovery

    Article • NeuroMolecular Medicine, June 2009, Springer Science + Business Media

    Professor Stuart Maudsley

  133. Live Longer sans the AT1A Receptor

    Article • Cell Metabolism, May 2009, Elsevier

    Professor Stuart Maudsley, Professor Stuart Maudsley

  134. Hormones in the naso-oropharynx: endocrine modulation of taste and smell

    Article • Trends in Endocrinology and Metabolism, May 2009, Elsevier

    Professor Stuart Maudsley, Professor Stuart Maudsley

  135. Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice

    Article • Hippocampus, March 2009, Wiley

    Professor Stuart Maudsley

  136. Diminished iron concentrations increase adenosine A2A receptor levels in mouse striatum and cultured human neuroblastoma cells

    Article • Experimental Neurology, February 2009, Elsevier

    Sergi Ferre, Professor Stuart Maudsley

  137. Exendin-4 Improves Glycemic Control, Ameliorates Brain and Pancreatic Pathologies, and Extends Survival in a Mouse Model of Huntington's Disease

    Article • Diabetes, February 2009, American Diabetes Association

    Professor Stuart Maudsley

  138. Gonadal Transcriptome Alterations in Response to Dietary Energy Intake: Sensing the Reproductive Environment

    Article • PLOS One, January 2009, PLOS

    Professor Stuart Maudsley

  139. Growth Factor Signals in Neural Cells

    Article • Journal of Biological Chemistry, January 2009, Elsevier

    Professor Stuart Maudsley

  140. Targeting TNF-α receptors for neurotherapeutics

    Article • Trends in Neurosciences, October 2008, Elsevier

    Professor Stuart Maudsley

  141. Caloric restriction: Impact upon pituitary function and reproduction

    Article • Ageing Research Reviews, October 2008, Elsevier

    Professor Stuart Maudsley

  142. iTRAQ Analysis of Complex Proteome Alterations in 3xTgAD Alzheimer's Mice: Understanding the Interface between Physiology and Disease

    Article • PLOS One, July 2008, PLOS

    Professor Stuart Maudsley

  143. Gonadotropin-Releasing Hormone Analog Structural Determinants of Selectivity for Inhibition of Cell Growth: Support for the Concept of Ligand-Induced Selective Signaling

    Article • Molecular Endocrinology, July 2008, Endocrine Society

    Professor Stuart Maudsley

  144. Conserved and Differential Effects of Dietary Energy Intake on the Hippocampal Transcriptomes of Females and Males

    Article • PLOS One, June 2008, PLOS

    Professor Stuart Maudsley

  145. Modulation of taste sensitivity by GLP‐1 signaling

    Article • Journal of Neurochemistry, April 2008, Wiley

    Professor Stuart Maudsley

  146. Mammalian Type I Gonadotropin-Releasing Hormone Receptors Undergo Slow, Constitutive, Agonist-Independent Internalization

    Article • Endocrinology, March 2008, Endocrine Society

    Professor Stuart Maudsley

  147. Impact of reduced meal frequency without caloric restriction on glucose regulation in healthy, normal-weight middle-aged men and women

    Article • Metabolism, December 2007, Elsevier

    Professor Stuart Maudsley

  148. Nuclear Stabilization of β-Catenin and Inactivation of Glycogen Synthase Kinase-3β by Gonadotropin-Releasing Hormone: Targeting Wnt Signaling in the Pituitary Gonadotrope

    Article • Molecular Endocrinology, December 2007, Endocrine Society

    Professor Stuart Maudsley

  149. Sex-Dependent Metabolic, Neuroendocrine, and Cognitive Responses to Dietary Energy Restriction and Excess

    Article • Endocrinology, September 2007, Endocrine Society

    Professor Stuart Maudsley

  150. GnRH-Mediated DAN Production Regulates the Transcription of the GnRH Receptor in Gonadotrope Cells

    Article • NeuroMolecular Medicine, August 2007, Springer Science + Business Media

    Professor Stuart Maudsley

  151. Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets

    Article • AJP Endocrinology and Metabolism, August 2007, American Physiological Society

    Professor Stuart Maudsley

  152. Proline-Rich Tyrosine Kinase 2 Mediates Gonadotropin-Releasing Hormone Signaling to a Specific Extracellularly Regulated Kinase-Sensitive Transcriptional Locus in the Luteinizing Hormone β-Subunit Gene

    Article • Molecular Endocrinology, May 2007, Endocrine Society

    Professor Stuart Maudsley

  153. Prophylactic treatment with paroxetine ameliorates behavioral deficits and retards the development of amyloid and tau pathologies in 3xTgAD mice

    Article • Experimental Neurology, May 2007, Elsevier

    Professor Stuart Maudsley

  154. Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma

    Article • Free Radical Biology and Medicine, March 2007, Elsevier

    Professor Stuart Maudsley

  155. G Protein-Coupled Receptor Signaling Complexity in Neuronal Tissue:Implications for Novel Therapeutics

    Article • Current Alzheimer Research, February 2007, Bentham Science Publishers

    Professor Stuart Maudsley

  156. Classification of Alzheimer Diagnosis from ADNI Plasma Biomarker Data

    Article • January 2007, ACM (Association for Computing Machinery)

    Professor Stuart Maudsley, Professor Stuart Maudsley

  157. Caloric restriction and intermittent fasting: Two potential diets for successful brain aging

    Article • Ageing Research Reviews, August 2006, Elsevier

    Professor Stuart Maudsley, Professor Stuart Maudsley

  158. Protein twists and turns in Alzheimer disease

    Article • Nature Medicine, April 2006, Nature

    Professor Stuart Maudsley, Professor Stuart Maudsley

  159. Gonadotropin-Releasing Hormone Functionally Antagonizes Testosterone Activation of the Human Androgen Receptor in Prostate Cells through Focal Adhesion Complexes Involving Hic-5

    Article • Neuroendocrinology, January 2006, Karger Publishers

    Professor Stuart Maudsley

  160. Inhibition of Human Type I Gonadotropin-Releasing Hormone Receptor (GnRHR) Function by Expression of a Human Type II GnRHR Gene Fragment

    Article • Endocrinology, June 2005, Endocrine Society

    Professor Stuart Maudsley

  161. The Origins of Diversity and Specificity in G Protein-Coupled Receptor Signaling

    Article • Journal of Pharmacology and Experimental Therapeutics, April 2005, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Stuart Maudsley

  162. Introduction

    Article • NeuroMolecular Medicine, January 2005, Springer Science + Business Media

    Professor Stuart Maudsley, Professor Stuart Maudsley

  163. Class II G Protein-Coupled Receptors and Their Ligands in Neuronal Function and Protection

    Article • NeuroMolecular Medicine, January 2005, Springer Science + Business Media

    Professor Stuart Maudsley, Professor Stuart Maudsley

  164. A neural signaling triumvirate that influences ageing and age-related disease: insulin/IGF-1, BDNF and serotonin

    Article • Ageing Research Reviews, November 2004, Elsevier

    Professor Stuart Maudsley, Professor Stuart Maudsley

  165. Gonadotropin-Releasing Hormone (GnRH) Antagonists Promote Proapoptotic Signaling in Peripheral Reproductive Tumor Cells by Activating a Gαi-Coupling State of the Type I GnRH Receptor

    Article • Cancer Research, October 2004, American Association for Cancer Research (AACR)

    Professor Stuart Maudsley

  166. BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders

    Article • Trends in Neurosciences, October 2004, Elsevier

    Professor Stuart Maudsley

  167. Elevated Prostaglandin EP2 Receptor in Endometrial Adenocarcinoma Cells Promotes Vascular Endothelial Growth Factor Expression via Cyclic 3′,5′-Adenosine Monophosphate-Mediated Transactivation of the Epidermal Growth Factor Receptor and Extracellular S...

    Article • Molecular Endocrinology, June 2004, Endocrine Society

    Professor Stuart Maudsley

  168. Gonadotropin-Releasing Hormone Receptors

    Article • Endocrine Reviews, April 2004, Endocrine Society

    Professor Stuart Maudsley, Professor Stuart Maudsley

  169. Gonadotropin-releasing Hormone-induced Activation of Diacylglycerol Kinase-ζ and Its Association with Active c-Src

    Article • Journal of Biological Chemistry, March 2004, Elsevier

    Professor Stuart Maudsley

  170. Cytoskeletal Reorganization Dependence of Signaling by the Gonadotropin-releasing Hormone Receptor

    Article • Journal of Biological Chemistry, January 2004, Elsevier

    Professor Stuart Maudsley

  171. Multiple Determinants for Rapid Agonist-Induced Internalization of a Nonmammalian Gonadotropin-Releasing Hormone Receptor: A Putative Palmitoylation Site and Threonine Doublet within the Carboxyl-Terminal Tail Are Critical

    Article • Endocrinology, September 2003, Endocrine Society

    Professor Stuart Maudsley

  172. Type II gonadotrophin-releasing hormone (GnRH-II) in reproductive biology

    Article • Reproduction, September 2003, Bioscientifica

    Professor Stuart Maudsley

  173. Evidence That Gonadotropin‐Releasing Hormone II Is Not a Physiological Regulator of Gonadotropin Secretion in Mammals

    Article • Journal of Neuroendocrinology, August 2003, Wiley

    Professor Stuart Maudsley

  174. A novel mammalian receptor for the evolutionarily conserved type II GnRH

    Article • Proceedings of the National Academy of Sciences, August 2001, Proceedings of the National Academy of Sciences

    Professor Stuart Maudsley

  175. Platelet-Derived Growth Factor Receptor Association with Na+/H+ Exchanger Regulatory Factor Potentiates Receptor Activity

    Article • Molecular and Cellular Biology, November 2000, ASM Journals

    Professor Stuart Maudsley

  176. Transactivation of the EGF Receptor Mediates IGF-1-stimulated Shc Phosphorylation and ERK1/2 Activation in COS-7 Cells

    Article • Journal of Biological Chemistry, July 2000, Elsevier

    Professor Stuart Maudsley

  177. β-Arrestin1 Interacts with the Catalytic Domain of the Tyrosine Kinase c-SRC

    Article • Journal of Biological Chemistry, April 2000, Elsevier

    Professor Stuart Maudsley

  178. The β2-Adrenergic Receptor Mediates Extracellular Signal-regulated Kinase Activation via Assembly of a Multi-receptor Complex with the Epidermal Growth Factor Receptor

    Article • Journal of Biological Chemistry, March 2000, Elsevier

    Professor Stuart Maudsley

  179. Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors

    Article • Proceedings of the National Academy of Sciences, February 2000, Proceedings of the National Academy of Sciences

    Professor Stuart Maudsley

  180. Pasteurella multocida Toxin Stimulates Mitogen-activated Protein Kinase via Gq/11-dependent Transactivation of the Epidermal Growth Factor Receptor

    Article • Journal of Biological Chemistry, January 2000, Elsevier

    Professor Stuart Maudsley

  181. Pleiotropic Coupling of G Protein-coupled Receptors to the Mitogen-activated Protein Kinase Cascade

    Article • Journal of Biological Chemistry, May 1999, Elsevier

    Professor Stuart Maudsley

  182. Conserved polar residues in the transmembrane domain of the human tachykinin NK2 receptor: functional roles and structural implications

    Article • Biochemical Journal, March 1999, Portland Press Ltd.

    Professor Stuart Maudsley

  183. β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes

    Article • Science, January 1999, American Association for the Advancement of Science

    Professor Stuart Maudsley

  184. Src-mediated Tyrosine Phosphorylation of Dynamin Is Required for β2-Adrenergic Receptor Internalization and Mitogen-activated Protein Kinase Signaling

    Article • Journal of Biological Chemistry, January 1999, Elsevier

    Professor Stuart Maudsley

  185. The relationship between the agonist‐induced activation and desensitization of the human tachykinin NK2 receptor expressed in Xenopus oocytes

    Article • British Journal of Pharmacology, June 1998, Wiley

    Professor Stuart Maudsley

  186. Inhibition of Ca2+‐sensitive K+ currents in NG 108‐15 cells by substance P and related tachykinins

    Article • British Journal of Pharmacology, September 1996, Wiley

    Professor Stuart Maudsley

  187. Isolation and characterization of goat C-reactive protein

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, April 1987, Elsevier

    Professor Stuart Maudsley

  188. Preliminary assessment of a multiwire camera for quantitative autoradiography of tritium-labelled substances

    Article • Physics in Medicine and Biology, May 1986, Institute of Physics Publishing

    Professor Stuart Maudsley