All Stories

  1. Perioperative redox changes in patients undergoing hepato-pancreatico-biliary cancer surgery

    Article • Perioperative Medicine, July 2023, Springer Science + Business Media

    Bernadette Fernandez

  2. Nitric oxide and long-term outcomes after kidney transplantation: Results of the TransplantLines cohort study

    Article • Nitric Oxide, August 2022, Elsevier

    Bernadette Fernandez

  3. Dietary Nitrate Supplementation Does Not Alter Exercise Efficiency at High Altitude – Further Results From the Xtreme Alps Study

    Article • Frontiers in Physiology, February 2022, Frontiers

    Bernadette Fernandez

  4. Dietary nitrate supplementation to enhance exercise capacity in hypoxic COPD: EDEN-OX, a double-blind, placebo-controlled, randomised cross-over study

    Article • Thorax, December 2021, BMJ

    Bernadette Fernandez

  5. Exercise Training Induces a Shift in Extracellular Redox Status with Alterations in the Pulmonary and Systemic Redox Landscape in Asthma

    Article • Antioxidants, November 2021, MDPI AG

    Bernadette Fernandez

  6. Plasma Nitrate Levels Are Related to Metabolic Syndrome and Are Not Altered by Treatment with DPP-4 Inhibitor Linagliptin: A Randomised, Placebo-Controlled Trial in Patients with Early Type 2 Diabetes Mellitus

    Article • Antioxidants, September 2021, MDPI AG

    Bernadette Fernandez

  7. Red Blood Cell and Endothelial eNOS Independently Regulate Circulating Nitric Oxide Metabolites and Blood Pressure

    Article • Circulation, September 2021, Wolters Kluwer Health

    Bernadette Fernandez

  8. Divergent trajectories of cellular bioenergetics, intermediary metabolism and systemic redox status in survivors and non-survivors of critical illness

    Article • Redox Biology, May 2021, Elsevier

    Bernadette Fernandez

  9. Circulating biomarkers of nitric oxide bioactivity and impaired muscle vasoreactivity to exercise in adults with uncomplicated type 1 diabetes

    Article • Diabetologia, November 2020, Springer Science + Business Media

    Bernadette Fernandez

  10. Exercise moderates inflammation in asthma through increased redox buffering capacity

    Article • September 2020, European Respiratory Society (ERS)

    Bernadette Fernandez

  11. HACASE: A simple and versatile framework for session design and delivery

    Article • MedEdPublish, July 2020, Faculty of 1000, Ltd.

    Bernadette Fernandez

  12. Effects of dietary nitrate supplementation on microvascular physiology at 4559 m altitude – A randomised controlled trial (Xtreme Alps)

    Article • Nitric Oxide, January 2020, Elsevier

    Bernadette Fernandez

  13. Oxidative Stress Response Following Transcatheter Aortic Valve Replacement

    Article • Oxidative Medicine and Cellular Longevity, November 2019, Hindawi Publishing Corporation

    Bernadette Fernandez, Gabriel Maluenda

  14. Characterising nitric oxide-mediated metabolic benefits of low-dose ultraviolet radiation in the mouse: a focus on brown adipose tissue

    Article • Diabetologia, November 2019, Springer Science + Business Media

    Bernadette Fernandez, Richard Weller

  15. Corrigendum to: Blueberries improve biomarkers of cardiometabolic function in participants with metabolic syndrome—results from a 6-month, double-blind, randomized controlled trial. Am J Clin Nutr 2019;109:1535-45

    Article • American Journal of Clinical Nutrition, November 2019, Elsevier

    Bernadette Fernandez

  16. Inorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humans

    Article • American Journal of Clinical Nutrition, October 2019, Oxford University Press (OUP)

    Dr David Vauzour, Bernadette Fernandez

  17. Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides and oxidation of protein kinase G 1α redox signaling

    Article • Cardiovascular Research, July 2019, Oxford University Press (OUP)

    Bernadette Fernandez

  18. Lower limb ischemic preconditioning combined with dietary nitrate supplementation does not influence time-trial performance in well-trained cyclists

    Article • Journal of Science and Medicine in Sport, July 2019, Elsevier

    Bernadette Fernandez

  19. Blueberries improve biomarkers of cardiometabolic function in participants with metabolic syndrome—results from a 6-month, double-blind, randomized controlled trial

    Article • American Journal of Clinical Nutrition, June 2019, Elsevier

    Bernadette Fernandez

  20. Reactive Species Interactome Alterations in Oocyte Donation Pregnancies in the Absence and Presence of Pre-Eclampsia

    Article • International Journal of Molecular Sciences, March 2019, MDPI AG

    Bernadette Fernandez

  21. Rapid free thiol rebound is a physiological response following cold‐induced vasoconstriction in healthy humans, primary Raynaud and systemic sclerosis

    Article • Physiological Reports, March 2019, Wiley

    Bernadette Fernandez

  22. Pushing arterial-venous plasma biomarkers to new heights: A model for personalised redox metabolomics?

    Article • Redox Biology, February 2019, Elsevier

    Bernadette Fernandez

  23. Endogenous H2S production deficiencies lead to impaired renal erythropoietin production

    Article • Canadian Urological Association Journal, November 2018, Canadian Urological Association Journal

    Bernadette Fernandez

  24. Pharmacological preconditioning with inhaled nitric oxide (NO): Organ-specific differences in the lifetime of blood and tissue NO metabolites

    Article • Nitric Oxide, November 2018, Elsevier

    Bernadette Fernandez

  25. Late Breaking Abstract - Dietary nitrate supplementation increases exercise endurance time in COPD patients using ambulatory oxygen

    Article • September 2018, European Respiratory Society (ERS)

    Dr Adam Lewis, Bernadette Fernandez

  26. FRI0426 Response of the reactive species interactome to hypothermia induced raynaud’s attack in primary raynaud and systemic sclerosis

    Article • June 2018, BMJ

    Bernadette Fernandez

  27. A robust and versatile mass spectrometry platform for comprehensive assessment of the thiol redox metabolome

    Article • Redox Biology, June 2018, Elsevier

    Bernadette Fernandez

  28. The effects of two different doses of ultraviolet-A light exposure on nitric oxide metabolites and cardiorespiratory outcomes

    Article • European Journal of Applied Physiology and Occupational Physiology, March 2018, Springer Science + Business Media

    Richard Weller, Bernadette Fernandez

  29. Nrf2 Deficiency Unmasks the Significance of Nitric Oxide Synthase Activity for Cardioprotection

    Article • Oxidative Medicine and Cellular Longevity, January 2018, Hindawi Publishing Corporation

    Bernadette Fernandez

  30. Effects of dietary nitrate on respiratory physiology at high altitude - Results from the Xtreme Alps study

    Article • Nitric Oxide, December 2017, Elsevier

    Bernadette Fernandez

  31. Does hypoxia play a role in the development of sarcopenia in humans? Mechanistic insights from the Caudwell Xtreme Everest Expedition

    Article • Redox Biology, October 2017, Elsevier

    Bernadette Fernandez, Hugh Montgomery

  32. Low-Dose Nitric Oxide as Targeted Anti-biofilm Adjunctive Therapy to Treat Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis

    Article • Molecular Therapy, September 2017, Elsevier

    Gary Connett, Bernadette Fernandez

  33. FRI0366 A pilot study on ischemia and reperfusion injury during a raynaud's attack: sequential assessment of redox stress parameters in a unique cooling and rewarming experiment

    Article • June 2017, BMJ

    Bernadette Fernandez

  34. Metabolic basis to Sherpa altitude adaptation

    Article • Proceedings of the National Academy of Sciences, May 2017, Proceedings of the National Academy of Sciences

    Bernadette Fernandez, Hugh Montgomery

  35. Changes in acute pulmonary vascular responsiveness to hypoxia during a progressive ascent to high altitude (5300 m)

    Article • Experimental Physiology, May 2017, Wiley

    Bernadette Fernandez

  36. Anti-Bacterial Mouthwash Reduces Plasma Nitrite Following Dietary Nitrate Supplementation but Does Not Alter Stress Response

    Article • Medicine & Science in Sports & Exercise, May 2017, Wolters Kluwer Health

    Bernadette Fernandez

  37. Beetroot juice versus chard gel: A pharmacokinetic and pharmacodynamic comparison of nitrate bioavailability

    Article • Nitric Oxide, April 2017, Elsevier

    Bernadette Fernandez

  38. Suppression of TAK1 pathway by shear stress counteracts the inflammatory endothelial cell phenotype induced by oxidative stress and TGF-β1

    Article • Scientific Reports, February 2017, Nature

    Bernadette Fernandez

  39. Human Second Window Pre-Conditioning and Post-Conditioning by Nitrite Is Influenced by a Common Polymorphism in Mitochondrial Aldehyde Dehydrogenase

    Article • JACC Basic to Translational Science, February 2017, Elsevier

    Bernadette Fernandez

  40. Inorganic Nitrate Mimics Exercise-Stimulated Muscular Fiber-Type Switching and Myokine and γ-Aminobutyric Acid Release

    Article • Diabetes, December 2016, American Diabetes Association

    Bernadette Fernandez

  41. Exposure of Stored Packed Erythrocytes to Nitric Oxide Prevents Transfusion-associated Pulmonary Hypertension

    Article • Anesthesiology, November 2016, Wolters Kluwer Health

    Bernadette Fernandez

  42. Nitrate-rich Beetroot Juice Vs. Nitrate-rich Chard Gel

    Article • Medicine & Science in Sports & Exercise, May 2016, Wolters Kluwer Health

    Bernadette Fernandez

  43. Combined Effects of Ischemic Preconditioning and Nitrate Supplementation on Submaximal Cycling Exercise and Time-trial Performance

    Article • Medicine & Science in Sports & Exercise, May 2016, Wolters Kluwer Health

    Bernadette Fernandez

  44. Dose-dependent Effects Of Uv-a Light On Nitric Oxide Bioavailability And Cardiometabolic Function In Humans

    Article • Medicine & Science in Sports & Exercise, May 2016, Wolters Kluwer Health

    Bernadette Fernandez

  45. Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism

    Article • BMC Biology, December 2015, Springer Science + Business Media

    Bernadette Fernandez

  46. Nitrosopersulfide (SSNO-) targets soluble guanylyl cyclase and induces vasodilation in vivo

    Article • BMC Pharmacology and Toxicology, September 2015, Springer Science + Business Media

    Bernadette Fernandez

  47. dl-propargylglycine reduces blood pressure and renal injury but increases kidney weight in angiotensin-II infused rats

    Article • Nitric Oxide, September 2015, Elsevier

    Bernadette Fernandez

  48. Key bioactive reaction products of the NO/H 2 S interaction are S/N-hybrid species, polysulfides, and nitroxyl

    Article • Proceedings of the National Academy of Sciences, July 2015, Proceedings of the National Academy of Sciences

    Bernadette Fernandez

  49. Inhaled Nitric Oxide as an Adjunctive Treatment for Cerebral Malaria in Children: A Phase II Randomized Open-Label Clinical Trial

    Article • Open Forum Infectious Diseases, July 2015, Oxford University Press (OUP)

    Bernadette Fernandez

  50. Short-Term Intravenous Sodium Nitrite Infusion Improves Cardiac and Pulmonary Hemodynamics in Heart Failure Patients

    Article • Circulation Heart Failure, April 2015, Wolters Kluwer Health

    Bernadette Fernandez

  51. On the chemical biology of the nitrite/sulfide interaction

    Article • Nitric Oxide, April 2015, Elsevier

    Bernadette Fernandez

  52. Systemic oxygen extraction during exercise at high altitude

    Article • British Journal of Anaesthesia, April 2015, Elsevier

    Bernadette Fernandez

  53. Suppression of erythropoiesis by dietary nitrate

    Article • The FASEB Journal, November 2014, Federation of American Societies For Experimental Biology (FASEB)

    Dr Andrew J Murray, Bernadette Fernandez

  54. Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart

    Article • The Journal of Physiology, October 2014, Wiley

    Bernadette Fernandez

  55. Autologous Transfusion of Stored Red Blood Cells Increases Pulmonary Artery Pressure

    Article • American Journal of Respiratory and Critical Care Medicine, October 2014, American Thoracic Society

    Bernadette Fernandez

  56. Inorganic Nitrate Promotes the Browning of White Adipose Tissue Through the Nitrate-Nitrite-Nitric Oxide Pathway

    Article • Diabetes, September 2014, American Diabetes Association

    Bernadette Fernandez

  57. Sunlight lowers blood pressure

    Article • Journal of Investigative Dermatology, July 2014, Elsevier

    Bernadette Fernandez, Richard Weller

  58. Effects of Prolonged Exposure to Hypobaric Hypoxia on Oxidative Stress, Inflammation and Gluco-Insular Regulation: The Not-So-Sweet Price for Good Regulation

    Article • PLoS ONE, April 2014, PLOS

    Bernadette Fernandez, Hugh Montgomery

  59. Short-term hypoxic vasodilationin vivois mediated by bioactive nitric oxide metabolites, rather than free nitric oxide derived from haemoglobin-mediated nitrite reduction

    Article • The Journal of Physiology, February 2014, Wiley

    Bernadette Fernandez

  60. Short-term hypoxic vasodilationin vivois mediated by bioactive nitric oxide metabolites, rather than free nitric oxide derived from haemoglobin-mediated nitrite reduction

    Article • The Journal of Physiology, January 2014, Wiley

    Bernadette Fernandez

  61. Nitrosopersulfide (SSNO−) accounts for sustained NO bioactivity of S-nitrosothiols following reaction with sulfide

    Article • Redox Biology, January 2014, Elsevier

    Bernadette Fernandez

  62. Design and conduct of ‘Xtreme Alps’: A double-blind, randomised controlled study of the effects of dietary nitrate supplementation on acclimatisation to high altitude

    Article • Contemporary Clinical Trials, November 2013, Elsevier

    Bernadette Fernandez

  63. Impact of chronic congestive heart failure on pharmacokinetics and vasomotor effects of infused nitrite

    Article • British Journal of Pharmacology, May 2013, Wiley

    Bernadette Fernandez

  64. Contributions of Nitric Oxide Synthases, Dietary Nitrite/Nitrate, and Other Sources to the Formation of NO Signaling Products

    Article • Antioxidants & Redox Signaling, August 2012, Mary Ann Liebert Inc

    Bernadette Fernandez

  65. NO effect produced by UVA irradiation of skin is independent of NOS and temperature

    Article • Nitric Oxide, July 2012, Elsevier

    Bernadette Fernandez, Richard Weller

  66. Transfusion of Stored Autologous Blood Does Not Alter Reactive Hyperemia Index in Healthy Volunteers

    Article • Anesthesiology, July 2012, Wolters Kluwer Health

    Bernadette Fernandez

  67. The role of nitrogen oxides in human adaptation to hypoxia

    Article • Scientific Reports, October 2011, Nature

    Bernadette Fernandez, Hugh Montgomery

  68. An integrated approach to assessing nitroso-redox balance in systemic inflammation

    Article • Free Radical Biology and Medicine, September 2011, Elsevier

    Bernadette Fernandez

  69. Redox-Sensitivity and Site-Specificity of S- and N- Denitrosation in Proteins

    Article • PLoS ONE, December 2010, PLOS

    Bernadette Fernandez

  70. Application of an Optimized TotalN-Nitrosamine (TONO) Assay to Pools: PlacingN-Nitrosodimethylamine (NDMA) Determinations into Perspective

    Article • Environmental Science & Technology, May 2010, American Chemical Society (ACS)

    Bernadette Fernandez

  71. Dermal Nitrite Application Enhances Global Nitric Oxide Availability: New Therapeutic Potential for Immunomodulation?

    Article • Journal of Investigative Dermatology, February 2010, Elsevier

    Bernadette Fernandez

  72. Hyperoxia-Induced Lung Injury in Gamma-Glutamyl Transferase Deficiency Is Associated with Alterations in Nitrosative and Nitrative Stress

    Article • American Journal Of Pathology, December 2009, Elsevier

    Bernadette Fernandez

  73. Glutathione peroxidase deficiency exacerbates ischemia-reperfusion injury in male but not female myocardium: insights into antioxidant compensatory mechanisms

    Article • AJP Heart and Circulatory Physiology, December 2009, American Physiological Society

    Bernadette Fernandez

  74. Mechanistic Insights Into Nitrite-Induced Cardioprotection Using an Integrated Metabolomic/Proteomic Approach

    Article • Circulation Research, February 2009, Wolters Kluwer Health

    Bernadette Fernandez

  75. Tissue Processing of Nitrite in Hypoxia

    Article • Journal of Biological Chemistry, October 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Bernadette Fernandez

  76. Brief Periods of Nitric Oxide Inhalation Protect against Myocardial Ischemia–Reperfusion Injury

    Article • Anesthesiology, October 2008, Wolters Kluwer Health

    Bernadette Fernandez

  77. Modulation of Nitrosative Stress by S-Nitrosoglutathione Reductase Is Critical for Thermotolerance and Plant Growth in Arabidopsis

    Article • The Plant Cell, March 2008, American Society of Plant Biologists (ASPB)

    Bernadette Fernandez

  78. N-Nitroso Products from the Reaction of Indoles with Angeli's Salt

    Article • Chemical Research in Toxicology, January 2006, American Chemical Society (ACS)

    Bernadette Fernandez

  79. Nitrite is a signaling molecule and regulator of gene expression in mammalian tissues

    Article • Nature Methods, September 2005, Nature

    Bernadette Fernandez

  80. Mechanisms of Reductive Nitrosylation in Iron and Copper Models Relevant to Biological Systems.

    Article • ChemInform, September 2005, Wiley

    Bernadette Fernandez

  81. Mechanisms of Reductive Nitrosylation in Iron and Copper Models Relevant to Biological Systems

    Article • Chemical Reviews, June 2005, American Chemical Society (ACS)

    Bernadette Fernandez

  82. Mechanisms of Ferriheme Reduction by Nitric Oxide:  Nitrite and General Base Catalysis1

    Article • Inorganic Chemistry, August 2004, American Chemical Society (ACS)

    Bernadette Fernandez

  83. Nitrite Catalyzes Ferriheme Protein Reductive Nitrosylation

    Article • Journal of the American Chemical Society, September 2003, American Chemical Society (ACS)

    Bernadette Fernandez

  84. Nitrite Catalyzes Reductive Nitrosylation of the Water-Soluble Ferri-Heme Model FeIII(TPPS) to FeII(TPPS)(NO)

    Article • Inorganic Chemistry, December 2002, American Chemical Society (ACS)

    Bernadette Fernandez