All Stories

  1. Repurposing HIV-Protease Inhibitor Precursors as Anticancer Agents: The Synthetic Molecule RDD-142 Delays Cell Cycle Progression and Induces Autophagy in HepG2 Cells with Enhanced Efficacy via Liposomal Formulation

    Article • International Journal of Molecular Sciences, October 2025, MDPI AG

    Lucia Chiummiento

  2. From insect lipids to biodiesel through the bioconversion process of vegetable by-products

    Article • Journal of Environmental Management, October 2025, Elsevier

    Lucia Chiummiento

  3. Recent Advances in Heterocyclic HIV Protease Inhibitors

    Article • International Journal of Molecular Sciences, September 2025, MDPI AG

    Lucia Chiummiento

  4. NCS-Mediated Ipso-Halogenation of Arylboronic Acids in Water Using Sodium Halides

    Article • ACS Omega, June 2025, American Chemical Society (ACS)

    Lucia Chiummiento

  5. N‐Iodosuccinimide in Oxidative Dimerization of Methyl Cinnamates

    Article • ChemistrySelect, October 2024, Wiley

    Lucia Chiummiento

  6. Unveiling the Relationship between Structure and Anticancer Properties of Permethylated Anigopreissin A: A Study with Thirteen Analogues

    Article • Organics, August 2024, MDPI AG

    Lucia Chiummiento

  7. Targeting Viral and Cellular Cysteine Proteases for Treatment of New Variants of SARS-CoV-2

    Article • Viruses, February 2024, MDPI AG

    Professor Antonio Rescifina, Lucia Chiummiento

  8. Novel wild type and mutate HIV-1 protease inhibitors containing heteroaryl carboxamides in P2: Synthesis, biological evaluations and in silico ADME prediction

    Article • Results in Chemistry, December 2023, Elsevier

    Lucia Chiummiento

  9. Reactivity Insights of Methoxyphenyl Boronic Acids in Rieche Formylation Reaction

    Article • ChemistrySelect, September 2023, Wiley

    Lucia Chiummiento

  10. Novel Wild Type and Mutate HIV-1 Protease Inhibitors Containing Heteroaryl Carboxamides in P2: Synthesis, Biological and ADME Evaluations

    Article • May 2023, MDPI AG

    Lucia Chiummiento

  11. PEGylated Liposomes Loaded with Carbamate Inhibitor ANP0903 Trigger Apoptosis by Enhancing ER Stress in HepG2 Cancer Cells

    Article • International Journal of Molecular Sciences, February 2023, MDPI AG

    Lucia Chiummiento

  12. Mitochondria-Mediated Apoptosis of HCC Cells Triggered by Knockdown of Glutamate Dehydrogenase 1: Perspective for Its Inhibition through Quercetin and Permethylated Anigopreissin A

    Article • Biomedicines, November 2021, MDPI AG

    Lucia Chiummiento

  13. Two Novel Precursors of the HIV-1 Protease Inhibitor Darunavir Target the UPR/Proteasome System in Human Hepatocellular Carcinoma Cell Line HepG2

    Article • Cells, November 2021, MDPI AG

    Lucia Chiummiento

  14. The Pseudo-Symmetric N-benzyl Hydroxyethylamine Core in a New Series of Heteroarylcarboxyamide HIV-1 Pr Inhibitors: Synthesis, Molecular Modeling and Biological Evaluation

    Article • Biomolecules, October 2021, MDPI AG

    Lucia Chiummiento

  15. The Pseudo-Symmetric N-benzyl Hydroxyethylamine Core in a New Series of Heteroarylcarboxyamide HIV-1 Pr Inhibitors: Synthesis, Molecular Modeling and Biological Evaluation

    Article • September 2021, MDPI AG

    Lucia Chiummiento

  16. Regio‐ and Diastereo‐Selective Biomimetic Synthesis of (±)‐ ϵ ‐Viniferin by NIS and Resveratrol

    Article • ChemistrySelect, July 2021, Wiley

    Lucia Chiummiento

  17. Biginelli Reaction and β-Secretase Inhibition: A Multicomponent Reaction as a Friendly Educational Approach to Bioactive Compounds

    Article • Journal of Chemical Education, April 2021, American Chemical Society (ACS)

    Lucia Chiummiento

  18. Access to 12-Membered Cyclic ortho,meta-Diarylheptanoids: Total Synthesis of Actinidione via Isomyricanone

    Article • The Journal of Organic Chemistry, January 2021, American Chemical Society (ACS)

    Lucia Chiummiento

  19. Structural Insights into the TES/TFA Reduction of Differently Substituted Benzofurans: Dihydrobenzofurans or Bibenzyls?

    Article • Synlett, October 2020, Thieme Publishing Group

    Lucia Chiummiento

  20. New synthesized polyoxygenated diarylheptanoids suppress lipopolysaccharide-induced neuroinflammation

    Article • Biochemical and Biophysical Research Communications, September 2020, Elsevier

    Lucia Chiummiento

  21. New Insights into the Exploitation of Vitis vinifera L. cv. Aglianico Leaf Extracts for Nutraceutical Purposes

    Article • Antioxidants, August 2020, MDPI AG

    Lucia Chiummiento

  22. Last Decade of Unconventional Methodologies for the Synthesis of Substituted Benzofurans

    Article • Molecules, May 2020, MDPI AG

    Lucia Chiummiento

  23. Recent Advances in Synthetic Strategies to 2,3-Dihydrobenzofurans

    Article • Synthesis, March 2020, Thieme Publishing Group

    Lucia Chiummiento

  24. Phytochemicals of Minthostachys diffusa Epling and Their Health-Promoting Bioactivities

    Article • Foods, February 2020, MDPI AG

    Lucia Chiummiento

  25. Green Chemistry, Circular Economy and Sustainable Development: An Operational Perspective to Scale Research Results in SMEs Practices

    Article • January 2020, Springer Science + Business Media

    Lucia Chiummiento

  26. Unintended Formation of a 26-Membered Cycle in the Course of a Novel Approach to Myricanol, a Strained [7,0]-Metacyclophane

    Article • Synlett, November 2019, Thieme Publishing Group

    Lucia Chiummiento

  27. Antioxidant, Antidiabetic, and Anticholinesterase Activities and Phytochemical Profile of Azorella glabra Wedd

    Article • Plants, August 2019, MDPI AG

    Lucia Chiummiento

  28. Regio- and Diastereoselective Organo-Zinc-Promoted Arylation oftrans-2,3-Diaryloxiranes by Arylboronic Acids: Stereoselective Access totrans-2,3-Diphenyl-2,3-dihydrobenzofuran

    Article • European Journal of Organic Chemistry, July 2019, Wiley

    Lucia Chiummiento

  29. New heteroaryl carbamates: Synthesis and biological screening in vitro and in mammalian cells of wild-type and mutant HIV-protease inhibitors

    Article • Bioorganic & Medicinal Chemistry, May 2019, Elsevier

    Lucia Chiummiento

  30. Future in the Past: Azorella glabra Wedd. as a Source of New Natural Compounds with Antiproliferative and Cytotoxic Activity on Multiple Myeloma Cells

    Article • International Journal of Molecular Sciences, October 2018, MDPI AG

    Lucia Chiummiento

  31. Antioxidant Activity and Phytochemical Characterization of Senecio clivicolus Wedd.

    Article • Molecules, September 2018, MDPI AG

    Lucia Chiummiento

  32. Mussel-Inspired Electro-Cross-Linking of Enzymes for the Development of Biosensors

    Article • ACS Applied Materials & Interfaces, May 2018, American Chemical Society (ACS)

    Lucia Chiummiento

  33. Convergent total synthesis of (±) myricanol, a cyclic natural diarylheptanoid

    Article • Organic & Biomolecular Chemistry, January 2018, Royal Society of Chemistry

    Lucia Chiummiento

  34. First application of homogeneous Pd nanoparticles prepared by pulsed laser ablation in liquid to a Suzuki-type reaction

    Article • Catalysis Communications, September 2017, Elsevier

    Lucia Chiummiento

  35. Synthesis and biological evaluation in vitro and in mammalian cells of new heteroaryl carboxyamides as HIV-protease inhibitors

    Article • Bioorganic & Medicinal Chemistry, September 2017, Elsevier

    Lucia Chiummiento

  36. Selective Claisen rearrangement and iodination for the synthesis of polyoxygenated allyl phenol derivatives

    Article • Tetrahedron Letters, September 2016, Elsevier

    Lucia Chiummiento

  37. A mild access to chiral syn 1,2-diaryl glycols by stereoselective ring opening of ortho substituted trans 2,3-diaryl-oxiranes using Amberlyst 15 in H2O/THF system

    Article • Tetrahedron, August 2015, Elsevier

    Lucia Chiummiento

  38. Permethylated Anigopreissin A inhibits human hepatoma cell proliferation by mitochondria-induced apoptosis

    Article • Chemico-Biological Interactions, July 2015, Elsevier

    Lucia Chiummiento

  39. Nickel-Catalyzed C-Br/C-H Bis-phenylation of Methyl 4-Bromocrotonate: A Stereoselective Entry to Methyl (E)-3,4-Diphenylbut-2-enoate

    Article • Synthetic Communications, June 2015, Taylor & Francis

    Lucia Chiummiento

  40. Practical and efficient ipso-iodination of arylboronic acids via KF/I2 system

    Article • Tetrahedron Letters, February 2015, Elsevier

    Lucia Chiummiento

  41. Synthesis and biological evaluation of new simple indolic non peptidic HIV Protease inhibitors: The effect of different substitution patterns

    Article • Bioorganic & Medicinal Chemistry, September 2014, Elsevier

    Lucia Chiummiento

  42. Ligand-Free Suzuki Coupling of Arylboronic Acids with Methyl (E)-4-Bromobut-2-enoate: Synthesis of Unconventional Cores of HIV-1 Protease Inhibitors

    Article • Organic Letters, July 2012, American Chemical Society (ACS)

    Lucia Chiummiento

  43. Synthesis and biological evaluation of novel small non-peptidic HIV-1 PIs: The benzothiophene ring as an effective moiety

    Article • Bioorganic & Medicinal Chemistry Letters, April 2012, Elsevier

    Lucia Chiummiento

  44. Heterocycles in Peptidomimetics and Pseudopeptides: Design and Synthesis

    Article • Pharmaceuticals, March 2012, MDPI AG

    Lucia Chiummiento

  45. Stereoselective intramolecular cyclization to 4-(hydroxymethyl)-3-(1H-indolyl)oxazolidin-2-ones

    Article • Chirality, February 2012, Wiley

    Lucia Chiummiento

  46. Concise Total Synthesis of Permethylated Anigopreissin A, a New Benzofuryl Resveratrol Dimer

    Article • European Journal of Organic Chemistry, November 2011, Wiley

    Lucia Chiummiento

  47. Efficient synthesis of 5-nitro-benzo[b]furans via 2-bromo-4-nitro-phenyl acetates

    Article • Tetrahedron Letters, May 2010, Elsevier

    Lucia Chiummiento

  48. Synthesis of New Thienyl Ring Containing HIV-1 Protease Inhibitors: Promising Preliminary Pharmacological Evaluation against Recombinant HIV-1 Proteases

    Article • Journal of Medicinal Chemistry, January 2010, American Chemical Society (ACS)

    Lucia Chiummiento

  49. New indolic non-peptidic HIV protease inhibitors from (S)-glycidol: synthesis and preliminary biological activity

    Article • Tetrahedron, August 2009, Elsevier

    Lucia Chiummiento

  50. A first convergent synthesis of the polyolic fragment of the antifungal pentaene macrolide strevertene A

    Article • Tetrahedron Letters, September 2008, Elsevier

    Lucia Chiummiento

  51. Stereoselective synthesis of versatile 2-chloromercurium-3,5-syn-dihydroxy esters via intramolecular oxymercuration

    Article • Tetrahedron, September 2008, Elsevier

    Lucia Chiummiento

  52. A Chemical/Computational Approach to the Determination of Absolute Configuration of Flexible and Transparent Molecules: Aliphatic Diols As a Case Study

    Article • The Journal of Organic Chemistry, June 2008, American Chemical Society (ACS)

    Lucia Chiummiento

  53. Novel Chiral Calix[4]arenes by Direct Asymmetric Epoxidation Reaction

    Article • The Journal of Organic Chemistry, April 2008, American Chemical Society (ACS)

    Lucia Chiummiento

  54. Application of Sharpless asymmetric dihydroxylation to thienyl- and benzothienyl acrylates and crotonates

    Article • Tetrahedron Asymmetry, November 2006, Elsevier

    Lucia Chiummiento

  55. A Concise and Efficient Stereoselective Synthesis of the C1-C11 Fragment of Macrolactin A

    Article • Synlett, September 2006, Thieme Publishing Group

    Lucia Chiummiento

  56. Direct Preparation of Z-1,3-Enyne Systems with a TMS-Propargylic Sulfone: Application of a One-Pot Julia Olefination

    Article • Synlett, August 2006, Thieme Publishing Group

    Lucia Chiummiento

  57. New Functionalised Hydroxymethyl Ketones from the Mild and Chemoselective KMnO4 Oxidation of Chiral Terminal Olefins

    Article • European Journal of Organic Chemistry, January 2006, Wiley

    Lucia Chiummiento

  58. Synthesis, biological activity and modelling studies of two novel anti HIV PR inhibitors with a thiophene containing hydroxyethylamino core

    Article • Tetrahedron, July 2005, Elsevier

    Lucia Chiummiento

  59. One-Pot Practical Preparation of Novel Propargylic Aryl and Heteroaryl Sulfides and Sulfones

    Article • Synlett, January 2005, Thieme Publishing Group

    Lucia Chiummiento

  60. Convergent Highly Stereoselective Preparation of the C12−C24 Fragment of Macrolactin A

    Article • The Journal of Organic Chemistry, June 2004, American Chemical Society (ACS)

    Lucia Chiummiento

  61. A convergent preparation of the C1–C13 fragment of amphotericin B from a single chiral precursor

    Article • Tetrahedron Letters, March 2004, Elsevier

    Lucia Chiummiento

  62. Synthesis of a first thiophene containing analog of the HIV protease inhibitor nelfinavir

    Article • Tetrahedron Letters, March 2004, Elsevier

    Lucia Chiummiento

  63. A general protocol for the regio high yielding opening of different glycidol derivatives

    Article • Tetrahedron Letters, March 2003, Elsevier

    Lucia Chiummiento

  64. Stereoselective synthesis of C15C24 and C25C30 fragments of dolabelides

    Article • Tetrahedron Letters, February 2003, Elsevier

    Lucia Chiummiento

  65. Preparation of chiral 1,3 skipped anti- and syn-tetrols via highly enantioselective biocatalytic resolution

    Article • Tetrahedron Asymmetry, October 2001, Elsevier

    Lucia Chiummiento

  66. N-(3-Benzo[b]thienyl)iminophosphoranes toward the Synthesis of Benzo[b]thieno[3,2-b]pyridines: Reactivity and Alternative Regioselectivity with α,β-unsaturated Ketones and Aldehydes

    Article • Tetrahedron, March 2000, Elsevier

    Lucia Chiummiento

  67. First Stereocontrolled Synthesis of the (3S,5R,7R,10R,11R)-C1−C13 Fragment of Nystatin A1

    Article • The Journal of Organic Chemistry, June 1999, American Chemical Society (ACS)

    Lucia Chiummiento

  68. Chiral polypropionate subunit by a chemoenzymatic approach

    Article • Tetrahedron Asymmetry, August 1998, Elsevier

    Lucia Chiummiento

  69. First enantioselective synthesis of (-)-seiridin the major phytotoxic metabolite of Seiridium species pathogenic for cypress

    Article • Tetrahedron Letters, October 1995, Elsevier

    Lucia Chiummiento

  70. Ring opening of 2,3-epoxy 1-tosylates to halohydrins and subsequent elaboration to asymmetrical alcohols

    Article • Tetrahedron Letters, January 1994, Elsevier

    Lucia Chiummiento