All Stories

  1. Functional conservation of divergent peptidase_M60 O-glycopeptidases in enterococcus
  2. Substrate recognition and cleavage by mucin degrading O-glycopeptidases from the gut microbe Bacteroides caccae
  3. Protein mannosylation in actinobacteria an enigmatic post-translational modification
  4. Determinants of undesired α2-6-sialoside formation by PmST1 M144D
  5. Differences in intrinsic cellular O-GlcNAcylation impact response to metabolic stress
  6. Differential substrate preferences IN ACTINOBACTERIAL protein O-MANNOSYLTRANSFERASES and alteration of protein-O-MANNOSYLATION by choice of secretion pathway
  7. PROTEIN-O-MANNOSYLATION BY NON-SEC/TAT SECRETION TRANSLOCONS IN ACTINOBACTERIA
  8. A high-throughput screening platform for enzymes active on mucin-type O-glycoproteins
  9. O-GlcNAc transferase modulates the cellular endocytosis machinery by controlling the formation of clathrin-coated pits
  10. Attenuation of Polysialic Acid Biosynthesis in Cells by the Small Molecule Inhibitor 8-Keto-sialic acid
  11. O-glycosylation and its role in therapeutic proteins
  12. A previously uncharacterized O-glycopeptidase from Akkermansia muciniphila requires the Tn-antigen for cleavage of the peptide bond
  13. Chitin-Active Lytic Polysaccharide Monooxygenases Are Rare in Cellulomonas Species
  14. O-GlcNAc transferase modulates formation of clathrin-coated pits
  15. Mammalian sialyltransferases allow efficient E. coli-based production of mucin-type O-glycoproteins but can also transfer Kdo.
  16. Quantifying Carbohydrate-Active Enzyme Activity with Glycoprotein Substrates Using Electrospray Ionization Mass Spectrometry and Center-of-Mass Monitoring
  17. Investigation of sequon engineering for improved O-glycosylation by the human polypeptide N-acetylgalactosaminyl transferase T2 isozyme and two orthologues
  18. Architecturally complex O -glycopeptidases are customized for mucin recognition and hydrolysis
  19. Engineering polysialic acid on Schwann cells using polysialyltransferase gene transfer or purified enzyme exposure for spinal cord injury transplantation
  20. Development of BODIPY labelled sialic acids as sialyltransferase substrates for direct detection of terminal galactose on N- and O-linked glycans
  21. Energetic adaptations: Metabolic control of endocytic membrane traffic
  22. Comparison of α2,6-Sialyltransferases for sialylation of therapeutic proteins
  23. Directed evolution of bacterial polysialyltransferases
  24. Genetics behind the Biosynthesis of Nonulosonic Acid-Containing Lipooligosaccharides in Campylobacter coli
  25. A Bacterial Expression Platform for Production of Therapeutic Proteins Containing Human-like O-Linked Glycans
  26. Genetics behind the biosynthesis of nonulosonic acid containing lipooligosaccharides in Campylobacter coli:
  27. X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid
  28. Recognition of protein-linked glycans as a determinant of peptidase activity
  29. Proteomic Analysis of the Secretome of Cellulomonas fimi ATCC 484 and Cellulomonas flavigena ATCC 482
  30. Construction of a hybrid β-hexosaminidase subunit capable of forming stable homodimers that hydrolyze GM2 ganglioside in vivo
  31. Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation
  32. Sialyltransferases with enhanced legionaminic acid transferase activity for the preparation of analogs of sialoglycoconjugates
  33. Looking at beta-glucosidases in the genome of C. fimi
  34. A plate-based high-throughput activity assay for polysialyltransferase from Neisseria meningitidis
  35. Review of phosphocholine substituents on bacterial pathogen glycans: Synthesis, structures and interactions with host proteins
  36. Biochemical Characterization of a Polysialyltransferase from Mannheimia haemolytica A2 and Comparison to Other Bacterial Polysialyltransferases
  37. In Cellulo Examination of a Beta-Alpha Hybrid Construct of Beta-Hexosaminidase A Subunits, Reported to Interact with the GM2 Activator Protein and Hydrolyze GM2 Ganglioside
  38. Structure-based mutagenic analysis of mechanism and substrate specificity in mammalian glycosyltransferases: Porcine ST3Gal-I
  39. A glyco-gold nanoparticle based assay for α-2,8-polysialyltransferase from Neisseria meningitidis
  40. Domain Organization of the Polymerizing Mannosyltransferases Involved in Synthesis of theEscherichia coliO8 and O9a Lipopolysaccharide O-antigens
  41. Biosynthesis of the Polymannose Lipopolysaccharide O-antigens fromEscherichia coliSerotypes O8 and O9a Requires a Unique Combination of Single- and Multiple-active Site Mannosyltransferases
  42. Enzymatic Engineering of Polysialic Acid on Cellsin Vitroandin VivoUsing a Purified Bacterial Polysialyltransferase
  43. Structures of Merkel Cell Polyomavirus VP1 Complexes Define a Sialic Acid Binding Site Required for Infection
  44. Helicobacter pylori β1,3-N-acetylglucosaminyltransferase for versatile synthesis of type 1 and type 2 poly-LacNAcs on N-linked, O-linked and I-antigen glycans
  45. Thiogalactopyranosides are Resistant to Hydrolysis by α-Galactosidases
  46. Small molecules containing hetero-bicyclic ring systems compete with UDP-Glc for binding to WaaG glycosyltransferase
  47. Characterization of α2,3- and α2,6-sialyltransferases from Helicobacter acinonychis
  48. Recognition of Sialylated Poly‐N‐acetyllactosamine Chains on N‐ and O‐Linked Glycans by Human and Avian Influenza A Virus Hemagglutinins
  49. Recognition of Sialylated Poly-N-acetyllactosamine Chains on N- and O-Linked Glycans by Human and Avian Influenza A Virus Hemagglutinins
  50. Identification and Characterization of a Lipopolysaccharide  ,2,3-Sialyltransferase from the Human Pathogen Helicobacter bizzozeronii
  51. Inhibition of Galactosyltransferases by a Novel Class of Donor Analogues
  52. Transition State Analysis of Vibrio cholerae Sialidase-Catalyzed Hydrolyses of Natural Substrate Analogues
  53. Genetics and molecular specificity of sialylation of Histophilus somni lipooligosaccharide (LOS) and the effect of LOS sialylation on Toll-like receptor-4 signaling
  54. Bacterial glycosyltransferases in molecular mimicry
  55. Structure and Mechanism of the Lipooligosaccharide Sialyltransferase fromNeisseria meningitidis
  56. Structural and Kinetic Analysis of Substrate Binding to the Sialyltransferase Cst-II fromCampylobacter jejuni
  57. Site-specific enzymatic polysialylation of therapeutic proteins using bacterial enzymes
  58. Enzymatic synthesis and properties of glycoconjugates with legionaminic acid as a replacement for neuraminic acid
  59. Fluorescence Activated Cell Sorting as a General Ultra-High-Throughput Screening Method for Directed Evolution of Glycosyltransferases
  60. 89. Demonstration of the in cellulo efficacy of pyrimethamine as a pharmacological chaperone for late onset Tay-Sachs Disease using a fluorescent GM2 ganglioside analogue
  61. A sensitive fluorescence-based assay for monitoring GM2 ganglioside hydrolysis in live patient cells and their lysates
  62. NMR Spectroscopic Characterization of the Sialyltransferase CstII from Campylobacter jejuni: Histidine 188 Is the General Base
  63. Structural insight into mammalian sialyltransferases
  64. Mechanistic Investigation of the Endo-α-N-acetylgalactosaminidase from Streptococcus pneumoniae R6
  65. Structural and Kinetic Characterizations of the Polysialic AcidO-Acetyltransferase OatWY fromNeisseria meningitidis
  66. A New Sialidase Mechanism
  67. Complete chemoenzymatic synthesis of the Forssman antigen using novel glycosyltransferases identified in Campylobacter jejuni and Pasteurella multocida
  68. The Structural Basis for T-antigen Hydrolysis byStreptococcus pneumoniae
  69. Chemo-enzymatic synthesis of poly-N-acetyllactosamine (poly-LacNAc) structures and their characterization for CGL2-galectin-mediated binding of ECM glycoproteins to biomaterial surfaces
  70. A β‐1,4‐Galactosyltransferase from Helicobacter pylori is an Efficient and Versatile Biocatalyst Displaying a Novel Activity for Thioglycoside Synthesis
  71. Characterization of the  -2,8-polysialyltransferase from Neisseria meningitidis with synthetic acceptors, and the development of a self-priming polysialyltransferase fusion enzyme
  72. Variants of the β1,3-Galactosyltransferase CgtB from the Bacterium Campylobacter Jejuni have Distinct Acceptor Specificities
  73. Distinct Endocytic Mechanisms of CD22 (Siglec-2) and Siglec-F Reflect Roles in Cell Signaling and Innate Immunity
  74. Structural Analysis of the α-2,3-Sialyltransferase Cst-I from Campylobacter jejuni in Apo and Substrate-Analogue Bound Forms ,
  75. Combination of UDP‐Glc(NAc) 4′‐Epimerase and Galactose Oxidase in a One‐Pot Synthesis of Biotinylated Nucleotide Sugars
  76. Mechanism of stabilization of Bacillus circulans xylanase upon the introduction of disulfide bonds
  77. Alternative donor substrates for inverting and retaining glycosyltransferases
  78. Identification of a Bifunctional Lipopolysaccharide Sialyltransferase inHaemophilus influenzae
  79. Using substrate engineering to harness enzymatic promiscuity and expand biological catalysis
  80. High-throughput screening methodology for the directed evolution of glycosyltransferases
  81. Chemical and Chemoenzymatic Synthesis of S‐Linked Ganglioside Analogues and Their Protein Conjugates for Use as Immunogens.
  82. Identification of a SialateO-Acetyltransferase fromCampylobacter jejuni
  83. Structural and Functional Characterization of PseC, an Aminotransferase Involved in the Biosynthesis of Pseudaminic Acid, an Essential Flagellar Modification in Helicobacter pylori
  84. Chemical and Chemoenzymatic Synthesis of S‐Linked Ganglioside Analogues and Their Protein Conjugates for Use as Immunogens
  85. Functional Characterization of Dehydratase/Aminotransferase Pairs fromHelicobacterandCampylobacter
  86. Erratum
  87. Chemoenzymatic synthesis of 2-azidoethyl-ganglio-oligosaccharides GD3, GT3, GM2, GD2, GT2, GM1, and GD1a
  88. Identification and Characterization of NeuB3 fromCampylobacter jejunias a Pseudaminic Acid Synthase
  89. Novel biosynthetic functions of lipopolysaccharide rfaJ homologs from Helicobacter pylori
  90. Structural and Mechanistic Analysis of Sialic Acid Synthase NeuB fromNeisseria meningitidisin Complex with Mn2+, Phosphoenolpyruvate, andN-Acetylmannosaminitol
  91. Analysis of Campylobacter jejuni capsular loci reveals multiple mechanisms for the generation of structural diversity and the ability to form complex heptoses
  92. A Single Bifunctional UDP-GlcNAc/Glc 4-Epimerase Supports the Synthesis of Three Cell Surface Glycoconjugates inCampylobacter jejuni
  93. Identification and Mechanism of a Bacterial Hydrolyzing UDP-N-Acetylglucosamine 2-Epimerase
  94. Intermediate Trapping on a Mutant Retaining α-Galactosyltransferase Identifies an Unexpected Aspartate Residue
  95. Evidence for Acquisition of the Lipooligosaccharide Biosynthesis Locus in Campylobacter jejuni GB11, a Strain Isolated from a Patient with Guillain-Barré Syndrome, by Horizontal Exchange
  96. Characterization of the  -1,2-N-acetylglucosaminyltransferase of Neisseria gonorrhoeae, a key control point in lipooligosaccharride biosynthesis
  97. Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analog
  98. Simplifying Oligosaccharide Synthesis: Efficient Synthesis of Lactosamine and Siaylated Lactosamine Oligosaccharide Donors.
  99. Large‐Scale In Vivo Synthesis of the Carbohydrate Moieties of Gangliosides GM1 and GM2 by Metabolically Engineered Escherichia coli
  100. Simplifying Oligosaccharide Synthesis:  Efficient Synthesis of Lactosamine and Siaylated Lactosamine Oligosaccharide Donors
  101. Preparative-Scale Chemoenzymatic Synthesis of Large Carbohydrate Assemblies Using α(1→4)-Galactosyltransferase⧸UDP-4′-Gal-Epimerase Fusion Protein
  102. One Step Closer to a Sweet Conclusion
  103. Incorporation of N-Acetylneuraminic Acid into Haemophilus somnus Lipooligosaccharide (LOS): Enhancement of Resistance to Serum and Reduction of LOS Antibody Binding
  104. The structures of the lipooligosaccharide and capsule polysaccharide of Campylobacter jejuni genome sequenced strain NCTC 11168
  105. Incorporation of N-Acetylneuraminic Acid into Haemophilus somnus Lipooligosaccharide (LOS): Enhancement of Resistance to Serum and Reduction of LOS Antibody Binding
  106. High-level expression of recombinant Neisseria CMP-sialic acid synthetase in Escherichia coli
  107. Mechanistic Studies of a Retaining α-Galactosyltransferase from Neisseria meningitidis,
  108. Mechanistic Studies of a Retaining α-Galactosyltransferase from Neisseria meningitidis
  109. The Genetic Bases for the Variation in the Lipo-oligosaccharide of the Mucosal Pathogen,Campylobacter jejuni
  110. Chemoenzymatic Iterative Synthesis of Difficult Linkages of Oligosaccharides on Soluble Polymeric Supports
  111. A Campylobacter jejuni gene associated with immune-mediated neuropathy
  112. Efficient Preparation of Natural and Synthetic Galactosides with a Recombinant β-1,4-Galactosyltransferase-/UDP-4‘-Gal Epimerase Fusion Protein
  113. Dependence of the Bi-functional Nature of a Sialyltransferase fromNeisseria meningitidison a Single Amino Acid Substitution
  114. Identification of a lipopolysaccharide α‐2,3‐sialyltransferase from Haemophilus influenzae
  115. Structure of a Sialic Acid-activating Synthetase, CMP-acylneuraminate Synthetase in the Presence and Absence of CDP
  116. FlaA1, a New Bifunctional UDP-GlcNAc C6Dehydratase/ C4Reductase fromHelicobacter pylori
  117. Polymer-supported and chemoenzymatic synthesis of the Neisseria meningitidis pentasaccharide: a methodological comparison
  118. Phase variation of a β‐1,3 galactosyltransferase involved in generation of the ganglioside GM1‐like lipo‐oligosaccharide of Campylobacter jejuni
  119. ChemInform Abstract: Enzymatic Synthesis of Oligosaccharide Analogues: Evaluation of UDP‐Gal Analogues as Donors for Three Retaining α‐Galactosyltransferases.
  120. Expression, Purification, and Biochemical Characterization of WbpP, a New UDP-GlcNAc C4 Epimerase fromPseudomonas aeruginosaSerotype O6
  121. Ready Access to Sialylated Oligosaccharide Donors
  122. Functional genomics of Helicobacter pylori: identification of a beta-1,4 galactosyltransferase and generation of mutants with altered lipopolysaccharide
  123. Biosynthesis of Ganglioside Mimics inCampylobacter jejuniOH4384
  124. Enzymatic Synthesis of Oligosaccharide Analogues:  Evaluation of UDP-Gal Analogues as Donors for Three Retaining α-Galactosyltransferases
  125. Glycosyl Fluorides Can Function as Substrates for Nucleotide Phosphosugar-dependent Glycosyltransferases
  126. The synthesis of sialylated oligosaccharides using a CMP-Neu5Ac synthetase/sialyltransferase fusion
  127. Development of an on-line preconcentration method for the analysis of pathogenic lipopolysaccharides using capillary electrophoresis–electrospray mass spectrometry
  128. Scan‐rate dependence in protein calorimetry: The reversible transitions of Bacillus circulans xylanase and a disulfide‐bridge mutant
  129. Structure of an α‐2,6‐sialylated lipooligosaccharide from Neisseria meningitidis immunotype L1
  130. Capsular polysaccharide synthesis in Streptococcus pneumoniae serotype 14: molecular analysis of the complete cps locus and identification of genes encoding glycosyltransferases required for the biosynthesis of the tetrasaccharide subunit
  131. Characterization of a Recombinant Neisseria Meningitidesα‐2,3‐Sialyltransferase and its Acceptor Specificity
  132. Positioning the Acid/Base Catalyst in a Glycosidase:  Studies with Bacillus circulans Xylanase
  133. Cloning of the Lipooligosaccharide α-2,3-Sialyltransferase from the Bacterial PathogensNeisseria meningitidisandNeisseria gonorrhoeae
  134. Characterization of a buried neutral histidine residue inBacillus circulansxylanase: Nmr assignments, pH titration, and hydrogen exchange
  135. Functional Relationships of the Genetic Locus Encoding the Glycosyltransferase Enzymes Involved in Expression of the Lacto-N-neotetraose Terminal Lipopolysaccharide Structure inNeisseria meningitidis
  136. Secondary structure and NMR assignments ofbacillus circulansxylanase
  137. Effects of both Shortening and Lengthening the Active Site Nucleophile of Bacillus circulans Xylanase on Catalytic Activity
  138. The p K a of the General Acid/Base Carboxyl Group of a Glycosidase Cycles during Catalysis:  A 13 C-NMR Study of ...
  139. Abnormally High pKa of an Active‐Site Glutamic Acid Residue in Bacillus Circulans Xylanase
  140. Expression of Trichoderma reesei and Trichoderma viride xylanases in Escherichia coli
  141. Mutational and crystallographic analyses of the active site residues of the bacillus circulans xylanase
  142. Thermostabilization of the Bacillus circulansxylanase by the introduction of disulfide bonds
  143. Amino acid sequence and thermostability of xylanase A from schizophyllum commune
  144. Overexpression of the Bacillus subtilis and circulans Xylanases in Escherichia coli
  145. Two GC-rich DNA elements ofChlamydomonas reinhardtii with complex arrangements of directly repeated sequence motifs
  146. Gametic differentiation in Chlamydomonas reinhardtii: light dependence and gene expression patterns
  147. The molecular cloning and expression of a cellobiase gene from anAgrobacterium inEscherichia coli
  148. α-Putrescinylthymine and the sensitivity of bacteriophageφW-14 DNA to restriction endonucleases
  149. The Preliminary Characterization of the  -Glucosidases of Cellulomonas fimi
  150. The Cellulase System of Cellulomonas fimi
  151. Isolation and Characterization of Escherichia coli Clones Expressing Cellulase Genes from Cellulomonas fimi
  152. Capillary Electrophoresis as an Assay Method for Monitoring Glycosyltransferase Activity
  153. Analysis of Bacterial Glycolipids by Capillary Electrophoresis-Electrospray Mass Spectrometry: Haemophilus influenzae and Neisseria meningitidis Lipopolysaccharides