All Stories

  1. Comparison of α2,6-Sialyltransferases for sialylation of therapeutic proteins
  2. Directed evolution of bacterial polysialyltransferases
  3. Genetics behind the Biosynthesis of Nonulosonic Acid-Containing Lipooligosaccharides in Campylobacter coli
  4. A Bacterial Expression Platform for Production of Therapeutic Proteins Containing Human-like O-Linked Glycans
  5. Genetics behind the biosynthesis of nonulosonic acid containing lipooligosaccharides in Campylobacter coli:
  6. X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid
  7. Recognition of protein-linked glycans as a determinant of peptidase activity
  8. Proteomic Analysis of the Secretome of Cellulomonas fimi ATCC 484 and Cellulomonas flavigena ATCC 482
  9. Construction of a hybrid β-hexosaminidase subunit capable of forming stable homodimers that hydrolyze GM2 ganglioside in vivo
  10. Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation
  11. Sialyltransferases with enhanced legionaminic acid transferase activity for the preparation of analogs of sialoglycoconjugates
  12. Looking at beta-glucosidases in the genome of C. fimi
  13. A plate-based high-throughput activity assay for polysialyltransferase from Neisseria meningitidis
  14. Review of phosphocholine substituents on bacterial pathogen glycans: Synthesis, structures and interactions with host proteins
  15. Biochemical Characterization of a Polysialyltransferase from Mannheimia haemolytica A2 and Comparison to Other Bacterial Polysialyltransferases
  16. In Cellulo Examination of a Beta-Alpha Hybrid Construct of Beta-Hexosaminidase A Subunits, Reported to Interact with the GM2 Activator Protein and Hydrolyze GM2 Ganglioside
  17. Structure-based mutagenic analysis of mechanism and substrate specificity in mammalian glycosyltransferases: Porcine ST3Gal-I
  18. A glyco-gold nanoparticle based assay for α-2,8-polysialyltransferase from Neisseria meningitidis
  19. Domain Organization of the Polymerizing Mannosyltransferases Involved in Synthesis of theEscherichia coliO8 and O9a Lipopolysaccharide O-antigens
  20. Biosynthesis of the Polymannose Lipopolysaccharide O-antigens fromEscherichia coliSerotypes O8 and O9a Requires a Unique Combination of Single- and Multiple-active Site Mannosyltransferases
  21. Enzymatic Engineering of Polysialic Acid on Cellsin Vitroandin VivoUsing a Purified Bacterial Polysialyltransferase
  22. Structures of Merkel Cell Polyomavirus VP1 Complexes Define a Sialic Acid Binding Site Required for Infection
  23. Helicobacter pylori β1,3-N-acetylglucosaminyltransferase for versatile synthesis of type 1 and type 2 poly-LacNAcs on N-linked, O-linked and I-antigen glycans
  24. Thiogalactopyranosides are Resistant to Hydrolysis by α-Galactosidases
  25. Small molecules containing hetero-bicyclic ring systems compete with UDP-Glc for binding to WaaG glycosyltransferase
  26. Characterization of α2,3- and α2,6-sialyltransferases from Helicobacter acinonychis
  27. Recognition of Sialylated Poly-N-acetyllactosamine Chains on N- and O-Linked Glycans by Human and Avian Influenza A Virus Hemagglutinins
  28. Recognition of Sialylated Poly-N-acetyllactosamine Chains on N- and O-Linked Glycans by Human and Avian Influenza A Virus Hemagglutinins
  29. Identification and Characterization of a Lipopolysaccharide  ,2,3-Sialyltransferase from the Human Pathogen Helicobacter bizzozeronii
  30. Inhibition of Galactosyltransferases by a Novel Class of Donor Analogues
  31. Transition State Analysis of Vibrio cholerae Sialidase-Catalyzed Hydrolyses of Natural Substrate Analogues
  32. Genetics and molecular specificity of sialylation of Histophilus somni lipooligosaccharide (LOS) and the effect of LOS sialylation on Toll-like receptor-4 signaling
  33. Bacterial glycosyltransferases in molecular mimicry
  34. Structure and Mechanism of the Lipooligosaccharide Sialyltransferase fromNeisseria meningitidis
  35. Structural and Kinetic Analysis of Substrate Binding to the Sialyltransferase Cst-II fromCampylobacter jejuni
  36. Site-specific enzymatic polysialylation of therapeutic proteins using bacterial enzymes
  37. Enzymatic synthesis and properties of glycoconjugates with legionaminic acid as a replacement for neuraminic acid
  38. Fluorescence Activated Cell Sorting as a General Ultra-High-Throughput Screening Method for Directed Evolution of Glycosyltransferases
  39. ChemInform Abstract: Enzymatic Synthesis of Oligosaccharide Analogues: Evaluation of UDP-Gal Analogues as Donors for Three Retaining α-Galactosyltransferases.
  40. 89. Demonstration of the in cellulo efficacy of pyrimethamine as a pharmacological chaperone for late onset Tay-Sachs Disease using a fluorescent GM2 ganglioside analogue
  41. A sensitive fluorescence-based assay for monitoring GM2 ganglioside hydrolysis in live patient cells and their lysates
  42. NMR Spectroscopic Characterization of the Sialyltransferase CstII from Campylobacter jejuni: Histidine 188 Is the General Base
  43. Structural insight into mammalian sialyltransferases
  44. Mechanistic Investigation of the Endo-α-N-acetylgalactosaminidase from Streptococcus pneumoniae R6
  45. Structural and Kinetic Characterizations of the Polysialic AcidO-Acetyltransferase OatWY fromNeisseria meningitidis
  46. A New Sialidase Mechanism
  47. Complete chemoenzymatic synthesis of the Forssman antigen using novel glycosyltransferases identified in Campylobacter jejuni and Pasteurella multocida
  48. The Structural Basis for T-antigen Hydrolysis byStreptococcus pneumoniae
  49. Chemo-enzymatic synthesis of poly-N-acetyllactosamine (poly-LacNAc) structures and their characterization for CGL2-galectin-mediated binding of ECM glycoproteins to biomaterial surfaces
  50. A β‐1,4‐Galactosyltransferase fromHelicobacter pyloriis an Efficient and Versatile Biocatalyst Displaying a Novel Activity for Thioglycoside Synthesis
  51. Abnormally High pKa of an Active-Site Glutamic Acid Residue in Bacillus Circulans Xylanase
  52. Characterization of the  -2,8-polysialyltransferase from Neisseria meningitidis with synthetic acceptors, and the development of a self-priming polysialyltransferase fusion enzyme
  53. Variants of the β1,3-Galactosyltransferase CgtB from the Bacterium Campylobacter Jejuni have Distinct Acceptor Specificities
  54. Distinct Endocytic Mechanisms of CD22 (Siglec-2) and Siglec-F Reflect Roles in Cell Signaling and Innate Immunity
  55. Structural Analysis of the α-2,3-Sialyltransferase Cst-I from Campylobacter jejuni in Apo and Substrate-Analogue Bound Forms,
  56. Combination of UDP-Glc(NAc) 4′-Epimerase and Galactose Oxidase in a One-Pot Synthesis of Biotinylated Nucleotide Sugars
  57. Mechanism of stabilization of Bacillus circulans xylanase upon the introduction of disulfide bonds
  58. Alternative donor substrates for inverting and retaining glycosyltransferases
  59. Identification of a Bifunctional Lipopolysaccharide Sialyltransferase inHaemophilus influenzae
  60. Using substrate engineering to harness enzymatic promiscuity and expand biological catalysis
  61. High-throughput screening methodology for the directed evolution of glycosyltransferases
  62. Chemical and Chemoenzymatic Synthesis of S-Linked Ganglioside Analogues and Their Protein Conjugates for Use as Immunogens.
  63. Identification of a SialateO-Acetyltransferase fromCampylobacter jejuni
  64. Structural and Functional Characterization of PseC, an Aminotransferase Involved in the Biosynthesis of Pseudaminic Acid, an Essential Flagellar Modification in Helicobacter pylori
  65. Chemical and Chemoenzymatic Synthesis of S-Linked Ganglioside Analogues and Their Protein Conjugates for Use as Immunogens
  66. Functional Characterization of Dehydratase/Aminotransferase Pairs fromHelicobacterandCampylobacter
  67. Erratum
  68. Chemoenzymatic synthesis of 2-azidoethyl-ganglio-oligosaccharides GD3, GT3, GM2, GD2, GT2, GM1, and GD1a
  69. Identification and Characterization of NeuB3 fromCampylobacter jejunias a Pseudaminic Acid Synthase
  70. Novel biosynthetic functions of lipopolysaccharide rfaJ homologs from Helicobacter pylori
  71. Structural and Mechanistic Analysis of Sialic Acid Synthase NeuB fromNeisseria meningitidisin Complex with Mn2+, Phosphoenolpyruvate, andN-Acetylmannosaminitol
  72. Analysis of Campylobacter jejuni capsular loci reveals multiple mechanisms for the generation of structural diversity and the ability to form complex heptoses
  73. A Single Bifunctional UDP-GlcNAc/Glc 4-Epimerase Supports the Synthesis of Three Cell Surface Glycoconjugates inCampylobacter jejuni
  74. Identification and Mechanism of a Bacterial Hydrolyzing UDP-N-Acetylglucosamine 2-Epimerase
  75. Intermediate Trapping on a Mutant Retaining α-Galactosyltransferase Identifies an Unexpected Aspartate Residue
  76. Evidence for Acquisition of the Lipooligosaccharide Biosynthesis Locus in Campylobacter jejuni GB11, a Strain Isolated from a Patient with Guillain-Barré Syndrome, by Horizontal Exchange
  77. Characterization of the  -1,2-N-acetylglucosaminyltransferase of Neisseria gonorrhoeae, a key control point in lipooligosaccharride biosynthesis
  78. Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analog
  79. Simplifying Oligosaccharide Synthesis: Efficient Synthesis of Lactosamine and Siaylated Lactosamine Oligosaccharide Donors.
  80. Large-Scale In Vivo Synthesis of the Carbohydrate Moieties of Gangliosides GM1 and GM2 by Metabolically Engineered Escherichia coli
  81. Simplifying Oligosaccharide Synthesis:  Efficient Synthesis of Lactosamine and Siaylated Lactosamine Oligosaccharide Donors
  82. Preparative-Scale Chemoenzymatic Synthesis of Large Carbohydrate Assemblies Using α(1→4)-Galactosyltransferase⧸UDP-4′-Gal-Epimerase Fusion Protein
  83. One Step Closer to a Sweet Conclusion
  84. Incorporation of N-Acetylneuraminic Acid into Haemophilus somnus Lipooligosaccharide (LOS): Enhancement of Resistance to Serum and Reduction of LOS Antibody Binding
  85. The structures of the lipooligosaccharide and capsule polysaccharide of Campylobacter jejuni genome sequenced strain NCTC 11168
  86. Incorporation of N-Acetylneuraminic Acid into Haemophilus somnus Lipooligosaccharide (LOS): Enhancement of Resistance to Serum and Reduction of LOS Antibody Binding
  87. High-level expression of recombinant Neisseria CMP-sialic acid synthetase in Escherichia coli
  88. Mechanistic Studies of a Retaining α-Galactosyltransferase from Neisseria meningitidis,
  89. Mechanistic Studies of a Retaining α-Galactosyltransferase from Neisseria meningitidis
  90. Phase variation of a β-1,3 galactosyltransferase involved in generation of the ganglioside GM1-like lipo-oligosaccharide of Campylobacter jejuni
  91. The Genetic Bases for the Variation in the Lipo-oligosaccharide of the Mucosal Pathogen,Campylobacter jejuni
  92. Chemoenzymatic Iterative Synthesis of Difficult Linkages of Oligosaccharides on Soluble Polymeric Supports
  93. A Campylobacter jejuni gene associated with immune-mediated neuropathy
  94. Efficient Preparation of Natural and Synthetic Galactosides with a Recombinant β-1,4-Galactosyltransferase-/UDP-4‘-Gal Epimerase Fusion Protein
  95. Dependence of the Bi-functional Nature of a Sialyltransferase fromNeisseria meningitidison a Single Amino Acid Substitution
  96. Identification of a lipopolysaccharide alpha-2,3-sialyltransferase from Haemophilus influenzae
  97. Structure of a Sialic Acid-activating Synthetase, CMP-acylneuraminate Synthetase in the Presence and Absence of CDP
  98. FlaA1, a New Bifunctional UDP-GlcNAc C6Dehydratase/ C4Reductase fromHelicobacter pylori
  99. Polymer-supported and chemoenzymatic synthesis of the Neisseria meningitidis pentasaccharide: a methodological comparison
  100. Expression, Purification, and Biochemical Characterization of WbpP, a New UDP-GlcNAc C4 Epimerase fromPseudomonas aeruginosaSerotype O6
  101. Ready Access to Sialylated Oligosaccharide Donors
  102. Functional genomics of Helicobacter pylori: identification of a beta-1,4 galactosyltransferase and generation of mutants with altered lipopolysaccharide
  103. Biosynthesis of Ganglioside Mimics inCampylobacter jejuniOH4384
  104. Enzymatic Synthesis of Oligosaccharide Analogues:  Evaluation of UDP-Gal Analogues as Donors for Three Retaining α-Galactosyltransferases
  105. Glycosyl Fluorides Can Function as Substrates for Nucleotide Phosphosugar-dependent Glycosyltransferases
  106. The synthesis of sialylated oligosaccharides using a CMP-Neu5Ac synthetase/sialyltransferase fusion
  107. Development of an on-line preconcentration method for the analysis of pathogenic lipopolysaccharides using capillary electrophoresis–electrospray mass spectrometry
  108. Scan-rate dependence in protein calorimetry: The reversible transitions ofBacillus circulansxylanase and a disulfide-bridge mutant
  109. Structure of an alpha-2,6-sialylated lipooligosaccharide from Neisseria meningitidis immunotype L1
  110. Capsular polysaccharide synthesis in Streptococcus pneumoniae serotype 14: molecular analysis of the complete cps locus and identification of genes encoding glycosyltransferases required for the biosynthesis of the tetrasaccharide subunit
  111. Characterization of a Recombinant Neisseria Meningitidesalpha-2,3-Sialyltransferase and its Acceptor Specificity
  112. Positioning the Acid/Base Catalyst in a Glycosidase:  Studies with Bacillus circulans Xylanase
  113. Cloning of the Lipooligosaccharide α-2,3-Sialyltransferase from the Bacterial PathogensNeisseria meningitidisandNeisseria gonorrhoeae
  114. Characterization of a buried neutral histidine residue inBacillus circulansxylanase: Nmr assignments, pH titration, and hydrogen exchange
  115. Functional Relationships of the Genetic Locus Encoding the Glycosyltransferase Enzymes Involved in Expression of the Lacto-N-neotetraose Terminal Lipopolysaccharide Structure inNeisseria meningitidis
  116. Secondary structure and NMR assignments ofbacillus circulansxylanase
  117. Effects of both Shortening and Lengthening the Active Site Nucleophile of Bacillus circulans Xylanase on Catalytic Activity
  118. The pKa of the General Acid/Base Carboxyl Group of a Glycosidase Cycles during Catalysis:  A 13C-NMR Study of Bacillus circulans Xylanase
  119. Expression ofTrichoderma reeseiandTrichoderma viridexylanases inEscherichia coli
  120. Mutational and crystallographic analyses of the active site residues of thebacillus circulansxylanase
  121. Thermostabilization of the Bacillus circulansxylanase by the introduction of disulfide bonds
  122. Amino acid sequence and thermostability of xylanase A from schizophyllum commune
  123. Overexpression of the Bacillus subtilis and circulans Xylanases in Escherichia coli
  124. Two GC-rich DNA elements ofChlamydomonas reinhardtii with complex arrangements of directly repeated sequence motifs
  125. Gametic differentiation in Chlamydomonas reinhardtii: light dependence and gene expression patterns
  126. The molecular cloning and expression of a cellobiase gene from anAgrobacterium inEscherichia coli
  127. α-Putrescinylthymine and the sensitivity of bacteriophageφW-14 DNA to restriction endonucleases
  128. The Preliminary Characterization of the  -Glucosidases of Cellulomonas fimi
  129. The Cellulase System of Cellulomonas fimi
  130. Isolation and Characterization of Escherichia coli Clones Expressing Cellulase Genes from Cellulomonas fimi
  131. Capillary Electrophoresis as an Assay Method for Monitoring Glycosyltransferase Activity
  132. Analysis of Bacterial Glycolipids by Capillary Electrophoresis-Electrospray Mass Spectrometry: Haemophilus influenzae and Neisseria meningitidis Lipopolysaccharides