Professor Warren Wakarchuk

All Stories

1. 
   Protein mannosylation in actinobacteria an enigmatic post-translational modification

   Article • RSC Chemical Biology, January 2026, Royal Society of Chemistry

   Professor Warren Wakarchuk

2. 
   Determinants of undesired α2-6-sialoside formation by PmST1 M144D

   Article • Organic & Biomolecular Chemistry, January 2026, Royal Society of Chemistry

   Professor Warren Wakarchuk

3. 
   Differences in intrinsic cellular O-GlcNAcylation impact response to metabolic stress

   Article • October 2025, Cold Spring Harbor Laboratory Press

   Professor Warren Wakarchuk

4. 
   Differential substrate preferences IN ACTINOBACTERIAL protein O-MANNOSYLTRANSFERASES and alteration of protein-O-MANNOSYLATION by choice of secretion pathway

   Article • Glycobiology, December 2024, Oxford University Press (OUP)

   Professor Warren Wakarchuk

5. 
   PROTEIN-O-MANNOSYLATION BY NON-SEC/TAT SECRETION TRANSLOCONS IN ACTINOBACTERIA

   Article • August 2023, Cold Spring Harbor Laboratory Press

   Professor Warren Wakarchuk

6. 
   A high-throughput screening platform for enzymes active on mucin-type O-glycoproteins

   Article • Nature Chemical Biology, August 2023, Springer Science + Business Media

   Professor Warren Wakarchuk

7. 
   O-GlcNAc transferase modulates the cellular endocytosis machinery by controlling the formation of clathrin-coated pits

   Article • Journal of Biological Chemistry, March 2023, Elsevier

   Professor Warren Wakarchuk

8. 
   Attenuation of Polysialic Acid Biosynthesis in Cells by the Small Molecule Inhibitor 8-Keto-sialic acid

   Article • ACS Chemical Biology, December 2022, American Chemical Society (ACS)

   Professor Warren Wakarchuk

9. 
   O-glycosylation and its role in therapeutic proteins

   Article • Bioscience Reports, October 2022, Portland Press Ltd.

   Professor Warren Wakarchuk

10. 
    A previously uncharacterized O-glycopeptidase from Akkermansia muciniphila requires the Tn-antigen for cleavage of the peptide bond

    Article • Journal of Biological Chemistry, October 2022, Elsevier

    Professor Warren Wakarchuk

11. 
    Chitin-Active Lytic Polysaccharide Monooxygenases Are Rare in Cellulomonas Species

    Article • Applied and Environmental Microbiology, August 2022, ASM Journals

    Professor Warren Wakarchuk

12. 
    O-GlcNAc transferase modulates formation of clathrin-coated pits

    Article • June 2022, Cold Spring Harbor Laboratory Press

    Professor Warren Wakarchuk

13. 
    Mammalian sialyltransferases allow efficient E. coli-based production of mucin-type O-glycoproteins but can also transfer Kdo.

    Article • Glycobiology, December 2021, Oxford University Press (OUP)

    Professor Warren Wakarchuk

14. 
    Quantifying Carbohydrate-Active Enzyme Activity with Glycoprotein Substrates Using Electrospray Ionization Mass Spectrometry and Center-of-Mass Monitoring

    Article • Analytical Chemistry, November 2021, American Chemical Society (ACS)

    Professor Warren Wakarchuk

15. 
    Investigation of sequon engineering for improved O-glycosylation by the human polypeptide N-acetylgalactosaminyl transferase T2 isozyme and two orthologues

    Article • Biochemical Journal, October 2021, Portland Press Ltd.

    Professor Warren Wakarchuk

16. 
    Architecturally complex O -glycopeptidases are customized for mucin recognition and hydrolysis

    Article • Proceedings of the National Academy of Sciences, March 2021, Proceedings of the National Academy of Sciences

    Professor Warren Wakarchuk

17. 
    Engineering polysialic acid on Schwann cells using polysialyltransferase gene transfer or purified enzyme exposure for spinal cord injury transplantation

    Article • Neuroscience Letters, March 2021, Elsevier

    Professor Warren Wakarchuk

18. 
    Development of BODIPY labelled sialic acids as sialyltransferase substrates for direct detection of terminal galactose on N- and O-linked glycans

    Article • Carbohydrate Research, February 2021, Elsevier

    Professor Warren Wakarchuk

19. 
    Energetic adaptations: Metabolic control of endocytic membrane traffic

    Article • Traffic, November 2019, Wiley

    Professor Warren Wakarchuk

20. 
    Comparison of α2,6-Sialyltransferases for sialylation of therapeutic proteins

    Article • Glycobiology, July 2019, Oxford University Press (OUP)

    Professor Warren Wakarchuk

21. 
    Directed evolution of bacterial polysialyltransferases

    Article • Glycobiology, April 2019, Oxford University Press (OUP)

    Professor Warren Wakarchuk

22. 
    Genetics behind the Biosynthesis of Nonulosonic Acid-Containing Lipooligosaccharides in Campylobacter coli

    Article • Journal of Bacteriology, January 2019, ASM Journals

    Professor Warren Wakarchuk

23. 
    A Bacterial Expression Platform for Production of Therapeutic Proteins Containing Human-like O-Linked Glycans

    Article • Cell Chemical Biology, November 2018, Elsevier

    Professor Warren Wakarchuk

24. 
    Genetics behind the biosynthesis of nonulosonic acid containing lipooligosaccharides in Campylobacter coli:

    Article • January 2018, Cold Spring Harbor Laboratory Press

    Professor Warren Wakarchuk

25. 
    X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid

    Article • Scientific Reports, July 2017, Springer Science + Business Media

    Professor Warren Wakarchuk

26. 
    Recognition of protein-linked glycans as a determinant of peptidase activity

    Article • Proceedings of the National Academy of Sciences, January 2017, Proceedings of the National Academy of Sciences

    Professor Warren Wakarchuk

27. 
    Proteomic Analysis of the Secretome of Cellulomonas fimi ATCC 484 and Cellulomonas flavigena ATCC 482

    Article • PLOS One, March 2016, PLOS

    Professor Warren Wakarchuk

28. 
    Construction of a hybrid β-hexosaminidase subunit capable of forming stable homodimers that hydrolyze GM2 ganglioside in vivo

    Article • Molecular Therapy — Methods & Clinical Development, January 2016, Elsevier

    Professor Warren Wakarchuk

29. 
    Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation

    Article • Nature Structural & Molecular Biology, July 2015, Nature

    Professor Warren Wakarchuk

30. 
    Sialyltransferases with enhanced legionaminic acid transferase activity for the preparation of analogs of sialoglycoconjugates

    Article • Glycobiology, April 2015, Oxford University Press (OUP)

    Professor Warren Wakarchuk

31. 
    Looking at beta-glucosidases in the genome of C. fimi

    Article • Journal of Bacteriology, September 2014, ASM Journals

    Professor Warren Wakarchuk

32. 
    A plate-based high-throughput activity assay for polysialyltransferase from Neisseria meningitidis

    Article • Analytical Biochemistry, January 2014, Elsevier

    Professor Warren Wakarchuk

33. 
    Review of phosphocholine substituents on bacterial pathogen glycans: Synthesis, structures and interactions with host proteins

    Article • Molecular Immunology, December 2013, Elsevier

    Professor Warren Wakarchuk

34. 
    Biochemical Characterization of a Polysialyltransferase from Mannheimia haemolytica A2 and Comparison to Other Bacterial Polysialyltransferases

    Article • PLOS One, July 2013, PLOS

    Professor Warren Wakarchuk

35. 
    In Cellulo Examination of a Beta-Alpha Hybrid Construct of Beta-Hexosaminidase A Subunits, Reported to Interact with the GM2 Activator Protein and Hydrolyze GM2 Ganglioside

    Article • PLOS One, March 2013, PLOS

    Professor Warren Wakarchuk

36. 
    Structure-based mutagenic analysis of mechanism and substrate specificity in mammalian glycosyltransferases: Porcine ST3Gal-I

    Article • Glycobiology, January 2013, Oxford University Press (OUP)

    Professor Warren Wakarchuk

37. 
    A glyco-gold nanoparticle based assay for α-2,8-polysialyltransferase from Neisseria meningitidis

    Article • Chemical Communications, January 2013, Royal Society of Chemistry

    Professor Warren Wakarchuk

38. 
    Domain Organization of the Polymerizing Mannosyltransferases Involved in Synthesis of theEscherichia coliO8 and O9a Lipopolysaccharide O-antigens

    Article • Journal of Biological Chemistry, September 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Warren Wakarchuk

39. 
    Biosynthesis of the Polymannose Lipopolysaccharide O-antigens fromEscherichia coliSerotypes O8 and O9a Requires a Unique Combination of Single- and Multiple-active Site Mannosyltransferases

    Article • Journal of Biological Chemistry, August 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Warren Wakarchuk

40. 
    Enzymatic Engineering of Polysialic Acid on Cellsin Vitroandin VivoUsing a Purified Bacterial Polysialyltransferase

    Article • Journal of Biological Chemistry, July 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Warren Wakarchuk

41. 
    Structures of Merkel Cell Polyomavirus VP1 Complexes Define a Sialic Acid Binding Site Required for Infection

    Article • PLoS Pathogens, July 2012, PLOS

    Professor Warren Wakarchuk

42. 
    Helicobacter pylori β1,3-N-acetylglucosaminyltransferase for versatile synthesis of type 1 and type 2 poly-LacNAcs on N-linked, O-linked and I-antigen glycans

    Article • Glycobiology, July 2012, Oxford University Press (OUP)

    Professor Warren Wakarchuk

43. 
    Thiogalactopyranosides are Resistant to Hydrolysis by α-Galactosidases

    Article • ChemBioChem, June 2012, Wiley

    Professor Warren Wakarchuk

44. 
    Small molecules containing hetero-bicyclic ring systems compete with UDP-Glc for binding to WaaG glycosyltransferase

    Article • Glycoconjugate Journal, June 2012, Springer Science + Business Media

    Professor Warren Wakarchuk

45. 
    Characterization of α2,3- and α2,6-sialyltransferases from Helicobacter acinonychis

    Article • Glycobiology, April 2012, Oxford University Press (OUP)

    Professor Warren Wakarchuk

46. 
    Recognition of Sialylated Poly‐N‐acetyllactosamine Chains on N‐ and O‐Linked Glycans by Human and Avian Influenza A Virus Hemagglutinins

    Article • Angewandte Chemie, April 2012, Wiley

    Professor Warren Wakarchuk

47. 
    Recognition of Sialylated Poly-N-acetyllactosamine Chains on N- and O-Linked Glycans by Human and Avian Influenza A Virus Hemagglutinins

    Article • Angewandte Chemie, April 2012, Wiley

    Professor Warren Wakarchuk

48. 
    Identification and Characterization of a Lipopolysaccharide  ,2,3-Sialyltransferase from the Human Pathogen Helicobacter bizzozeronii

    Article • Journal of Bacteriology, March 2012, ASM Journals

    Professor Warren Wakarchuk

49. 
    Inhibition of Galactosyltransferases by a Novel Class of Donor Analogues

    Article • Journal of Medicinal Chemistry, February 2012, American Chemical Society (ACS)

    Professor Warren Wakarchuk

50. 
    Transition State Analysis of Vibrio cholerae Sialidase-Catalyzed Hydrolyses of Natural Substrate Analogues

    Article • Journal of the American Chemical Society, February 2012, American Chemical Society (ACS)

    Professor Warren Wakarchuk

51. 
    Genetics and molecular specificity of sialylation of Histophilus somni lipooligosaccharide (LOS) and the effect of LOS sialylation on Toll-like receptor-4 signaling

    Article • Veterinary Microbiology, November 2011, Elsevier

    Dr Thomas J Inzana, Professor Warren Wakarchuk

52. 
    Bacterial glycosyltransferases in molecular mimicry

    Article • October 2011, Taylor & Francis

    Professor Warren Wakarchuk

53. 
    Structure and Mechanism of the Lipooligosaccharide Sialyltransferase fromNeisseria meningitidis

    Article • Journal of Biological Chemistry, August 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Warren Wakarchuk

54. 
    Structural and Kinetic Analysis of Substrate Binding to the Sialyltransferase Cst-II fromCampylobacter jejuni

    Article • Journal of Biological Chemistry, August 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Warren Wakarchuk

55. 
    Site-specific enzymatic polysialylation of therapeutic proteins using bacterial enzymes

    Article • Proceedings of the National Academy of Sciences, April 2011, Proceedings of the National Academy of Sciences

    Professor Warren Wakarchuk

56. 
    Enzymatic synthesis and properties of glycoconjugates with legionaminic acid as a replacement for neuraminic acid

    Article • Glycobiology, October 2010, Oxford University Press (OUP)

    Professor Warren Wakarchuk

57. 
    Fluorescence Activated Cell Sorting as a General Ultra-High-Throughput Screening Method for Directed Evolution of Glycosyltransferases

    Article • Journal of the American Chemical Society, July 2010, American Chemical Society (ACS)

    Professor Warren Wakarchuk

58. 
    89. Demonstration of the in cellulo efficacy of pyrimethamine as a pharmacological chaperone for late onset Tay-Sachs Disease using a fluorescent GM2 ganglioside analogue

    Article • Molecular Genetics and Metabolism, February 2010, Elsevier

    Professor Warren Wakarchuk

59. 
    A sensitive fluorescence-based assay for monitoring GM2 ganglioside hydrolysis in live patient cells and their lysates

    Article • Glycobiology, November 2009, Oxford University Press (OUP)

    Professor Warren Wakarchuk

60. 
    NMR Spectroscopic Characterization of the Sialyltransferase CstII from Campylobacter jejuni: Histidine 188 Is the General Base

    Article • Biochemistry, November 2009, American Chemical Society (ACS)

    Professor Warren Wakarchuk

61. 
    Structural insight into mammalian sialyltransferases

    Article • Nature Structural & Molecular Biology, October 2009, Springer Science + Business Media

    Professor Warren Wakarchuk

62. 
    Mechanistic Investigation of the Endo-α-N-acetylgalactosaminidase from Streptococcus pneumoniae R6

    Article • Biochemistry, October 2009, American Chemical Society (ACS)

    Professor Warren Wakarchuk

63. 
    Structural and Kinetic Characterizations of the Polysialic AcidO-Acetyltransferase OatWY fromNeisseria meningitidis

    Article • Journal of Biological Chemistry, June 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Warren Wakarchuk

64. 
    A New Sialidase Mechanism

    Article • Journal of Biological Chemistry, May 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Warren Wakarchuk

65. 
    Complete chemoenzymatic synthesis of the Forssman antigen using novel glycosyltransferases identified in Campylobacter jejuni and Pasteurella multocida

    Article • Glycobiology, October 2008, Oxford University Press (OUP)

    Professor Warren Wakarchuk

66. 
    The Structural Basis for T-antigen Hydrolysis byStreptococcus pneumoniae

    Article • Journal of Biological Chemistry, September 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Warren Wakarchuk

67. 
    Chemo-enzymatic synthesis of poly-N-acetyllactosamine (poly-LacNAc) structures and their characterization for CGL2-galectin-mediated binding of ECM glycoproteins to biomaterial surfaces

    Article • Glycoconjugate Journal, August 2008, Springer Science + Business Media

    Professor Vladimir Kren, Professor Warren Wakarchuk

68. 
    A β‐1,4‐Galactosyltransferase from Helicobacter pylori is an Efficient and Versatile Biocatalyst Displaying a Novel Activity for Thioglycoside Synthesis

    Article • ChemBioChem, June 2008, Wiley

    Professor Warren Wakarchuk

69. 
    Characterization of the  -2,8-polysialyltransferase from Neisseria meningitidis with synthetic acceptors, and the development of a self-priming polysialyltransferase fusion enzyme

    Article • Glycobiology, November 2007, Oxford University Press (OUP)

    Professor Warren Wakarchuk

70. 
    Variants of the β1,3-Galactosyltransferase CgtB from the Bacterium Campylobacter Jejuni have Distinct Acceptor Specificities

    Article • Glycobiology, August 2007, Oxford University Press (OUP)

    Professor Warren Wakarchuk

71. 
    Distinct Endocytic Mechanisms of CD22 (Siglec-2) and Siglec-F Reflect Roles in Cell Signaling and Innate Immunity

    Article • Molecular and Cellular Biology, June 2007, ASM Journals

    Professor Warren Wakarchuk

72. 
    Structural Analysis of the α-2,3-Sialyltransferase Cst-I from Campylobacter jejuni in Apo and Substrate-Analogue Bound Forms,

    Article • Biochemistry, May 2007, American Chemical Society (ACS)

    Professor Warren Wakarchuk

73. 
    Combination of UDP‐Glc(NAc) 4′‐Epimerase and Galactose Oxidase in a One‐Pot Synthesis of Biotinylated Nucleotide Sugars

    Article • Advanced Synthesis & Catalysis, February 2007, Wiley

    Professor Warren Wakarchuk

74. 
    Mechanism of stabilization of Bacillus circulans xylanase upon the introduction of disulfide bonds

    Article • Biophysical Chemistry, February 2007, Elsevier

    Professor Warren Wakarchuk

75. 
    Alternative donor substrates for inverting and retaining glycosyltransferases

    Article • Chemical Communications, January 2007, Royal Society of Chemistry

    Professor Warren Wakarchuk

76. 
    Identification of a Bifunctional Lipopolysaccharide Sialyltransferase inHaemophilus influenzae

    Article • Journal of Biological Chemistry, October 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Warren Wakarchuk

77. 
    Using substrate engineering to harness enzymatic promiscuity and expand biological catalysis

    Article • Nature Chemical Biology, October 2006, Springer Science + Business Media

    Professor Warren Wakarchuk

78. 
    High-throughput screening methodology for the directed evolution of glycosyltransferases

    Article • Nature Chemical Biology, July 2006, Springer Science + Business Media

    Professor Warren Wakarchuk

79. 
    Chemical and Chemoenzymatic Synthesis of S‐Linked Ganglioside Analogues and Their Protein Conjugates for Use as Immunogens.

    Article • ChemInform, March 2006, Wiley

    Professor Warren Wakarchuk

80. 
    Identification of a SialateO-Acetyltransferase fromCampylobacter jejuni

    Article • Journal of Biological Chemistry, February 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Warren Wakarchuk

81. 
    Structural and Functional Characterization of PseC, an Aminotransferase Involved in the Biosynthesis of Pseudaminic Acid, an Essential Flagellar Modification in Helicobacter pylori

    Article • Journal of Biological Chemistry, January 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vladimir V Lunin, Dr Jean-Philippe Julien, Professor Warren Wakarchuk

82. 
    Chemical and Chemoenzymatic Synthesis of S‐Linked Ganglioside Analogues and Their Protein Conjugates for Use as Immunogens

    Article • Chemistry - A European Journal, January 2006, Wiley

    Professor Warren Wakarchuk

83. 
    Functional Characterization of Dehydratase/Aminotransferase Pairs fromHelicobacterandCampylobacter

    Article • Journal of Biological Chemistry, November 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Warren Wakarchuk, Dennis M. Whitfield

84. 
    Erratum

    Article • Glycobiology, November 2005, Oxford University Press (OUP)

    Professor Warren Wakarchuk

85. 
    Chemoenzymatic synthesis of 2-azidoethyl-ganglio-oligosaccharides GD3, GT3, GM2, GD2, GT2, GM1, and GD1a

    Article • Carbohydrate Research, September 2005, Elsevier

    Professor Warren Wakarchuk

86. 
    Identification and Characterization of NeuB3 fromCampylobacter jejunias a Pseudaminic Acid Synthase

    Article • Journal of Biological Chemistry, August 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Warren Wakarchuk

87. 
    Novel biosynthetic functions of lipopolysaccharide rfaJ homologs from Helicobacter pylori

    Article • Glycobiology, April 2005, Oxford University Press (OUP)

    Professor Warren Wakarchuk

88. 
    Structural and Mechanistic Analysis of Sialic Acid Synthase NeuB fromNeisseria meningitidisin Complex with Mn2+, Phosphoenolpyruvate, andN-Acetylmannosaminitol

    Article • Journal of Biological Chemistry, October 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Warren Wakarchuk

89. 
    Analysis of Campylobacter jejuni capsular loci reveals multiple mechanisms for the generation of structural diversity and the ability to form complex heptoses

    Article • Molecular Microbiology, October 2004, Wiley

    Andrey Karlyshev, Professor Warren Wakarchuk, Professor Julian Parkhill

90. 
    A Single Bifunctional UDP-GlcNAc/Glc 4-Epimerase Supports the Synthesis of Three Cell Surface Glycoconjugates inCampylobacter jejuni

    Article • Journal of Biological Chemistry, October 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Warren Wakarchuk

91. 
    Identification and Mechanism of a Bacterial Hydrolyzing UDP-N-Acetylglucosamine 2-Epimerase

    Article • Biochemistry, October 2004, American Chemical Society (ACS)

    Professor Warren Wakarchuk

92. 
    Intermediate Trapping on a Mutant Retaining α-Galactosyltransferase Identifies an Unexpected Aspartate Residue

    Article • Journal of Biological Chemistry, April 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Warren Wakarchuk

93. 
    Evidence for Acquisition of the Lipooligosaccharide Biosynthesis Locus in Campylobacter jejuni GB11, a Strain Isolated from a Patient with Guillain-Barré Syndrome, by Horizontal Exchange

    Article • Infection and Immunity, February 2004, ASM Journals

    Professor Warren Wakarchuk

94. 
    Characterization of the  -1,2-N-acetylglucosaminyltransferase of Neisseria gonorrhoeae, a key control point in lipooligosaccharride biosynthesis

    Article • Glycobiology, January 2004, Oxford University Press (OUP)

    Professor Warren Wakarchuk, Dennis M. Whitfield

95. 
    Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analog

    Article • Nature Structural & Molecular Biology, January 2004, Springer Science + Business Media

    Professor Warren Wakarchuk

96. 
    Simplifying Oligosaccharide Synthesis: Efficient Synthesis of Lactosamine and Siaylated Lactosamine Oligosaccharide Donors.

    Article • ChemInform, June 2003, Wiley

    Professor Warren Wakarchuk

97. 
    Large‐Scale In Vivo Synthesis of the Carbohydrate Moieties of Gangliosides GM1 and GM2 by Metabolically Engineered Escherichia coli

    Article • ChemBioChem, May 2003, Wiley

    Professor Warren Wakarchuk

98. 
    Simplifying Oligosaccharide Synthesis:  Efficient Synthesis of Lactosamine and Siaylated Lactosamine Oligosaccharide Donors

    Article • The Journal of Organic Chemistry, February 2003, American Chemical Society (ACS)

    Professor Warren Wakarchuk, Dennis M. Whitfield

99. 
    Preparative-Scale Chemoenzymatic Synthesis of Large Carbohydrate Assemblies Using α(1→4)-Galactosyltransferase⧸UDP-4′-Gal-Epimerase Fusion Protein

    Article • January 2003, Elsevier

    Professor Warren Wakarchuk

100. 
     One Step Closer to a Sweet Conclusion

     Article • Chemistry & Biology, December 2002, Elsevier

     Professor Warren Wakarchuk

101. 
     Incorporation of N-Acetylneuraminic Acid into Haemophilus somnus Lipooligosaccharide (LOS): Enhancement of Resistance to Serum and Reduction of LOS Antibody Binding

     Article • Infection and Immunity, November 2002, ASM Journals

     Professor Warren Wakarchuk

102. 
     The structures of the lipooligosaccharide and capsule polysaccharide of Campylobacter jejuni genome sequenced strain NCTC 11168

     Article • FEBS Journal, October 2002, Wiley

     Professor Warren Wakarchuk

103. 
     Incorporation of N-Acetylneuraminic Acid into Haemophilus somnus Lipooligosaccharide (LOS): Enhancement of Resistance to Serum and Reduction of LOS Antibody Binding

     Article • Infection and Immunity, September 2002, ASM Journals

     Professor Warren Wakarchuk

104. 
     High-level expression of recombinant Neisseria CMP-sialic acid synthetase in Escherichia coli

     Article • Protein Expression and Purification, July 2002, Elsevier

     Professor Warren Wakarchuk

105. 
     Mechanistic Studies of a Retaining α-Galactosyltransferase from Neisseria meningitidis,

     Article • Biochemistry, April 2002, American Chemical Society (ACS)

     Professor Warren Wakarchuk

106. 
     Mechanistic Studies of a Retaining α-Galactosyltransferase from Neisseria meningitidis

     Article • Biochemistry, March 2002, American Chemical Society (ACS)

     Professor Warren Wakarchuk

107. 
     The Genetic Bases for the Variation in the Lipo-oligosaccharide of the Mucosal Pathogen,Campylobacter jejuni

     Article • Journal of Biological Chemistry, October 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

     Professor Warren Wakarchuk

108. 
     Chemoenzymatic Iterative Synthesis of Difficult Linkages of Oligosaccharides on Soluble Polymeric Supports

     Article • Organic Letters, October 2001, American Chemical Society (ACS)

     Professor Warren Wakarchuk, Dennis M. Whitfield

109. 
     A Campylobacter jejuni gene associated with immune-mediated neuropathy

     Article • Nature Reports Stem Cells, July 2001, Nature

     Professor Warren Wakarchuk

110. 
     Efficient Preparation of Natural and Synthetic Galactosides with a Recombinant β-1,4-Galactosyltransferase-/UDP-4‘-Gal Epimerase Fusion Protein

     Article • The Journal of Organic Chemistry, March 2001, American Chemical Society (ACS)

     Professor Warren Wakarchuk

111. 
     Article • Nature Structural Biology, February 2001, Springer Science + Business Media

     Professor Warren Wakarchuk

112. 
     Dependence of the Bi-functional Nature of a Sialyltransferase fromNeisseria meningitidison a Single Amino Acid Substitution

     Article • Journal of Biological Chemistry, January 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

     Professor Warren Wakarchuk

113. 
     Identification of a lipopolysaccharide α‐2,3‐sialyltransferase from Haemophilus influenzae

     Article • Molecular Microbiology, January 2001, Wiley

     Professor Warren Wakarchuk

114. 
     Structure of a Sialic Acid-activating Synthetase, CMP-acylneuraminate Synthetase in the Presence and Absence of CDP

     Article • Journal of Biological Chemistry, December 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

     Professor Warren Wakarchuk

115. 
     FlaA1, a New Bifunctional UDP-GlcNAc C6Dehydratase/ C4Reductase fromHelicobacter pylori

     Article • Journal of Biological Chemistry, August 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

     Professor Warren Wakarchuk

116. 
     Polymer-supported and chemoenzymatic synthesis of the Neisseria meningitidis pentasaccharide: a methodological comparison

     Article • Carbohydrate Research, August 2000, Elsevier

     Professor Warren Wakarchuk, Dennis M. Whitfield

117. 
     Phase variation of a β‐1,3 galactosyltransferase involved in generation of the ganglioside GM1‐like lipo‐oligosaccharide of Campylobacter jejuni

     Article • Molecular Microbiology, August 2000, Wiley

     Professor Warren Wakarchuk

118. 
     ChemInform Abstract: Enzymatic Synthesis of Oligosaccharide Analogues: Evaluation of UDP‐Gal Analogues as Donors for Three Retaining α‐Galactosyltransferases.

     Article • ChemInform, May 2000, Wiley

     Professor Warren Wakarchuk

119. 
     Expression, Purification, and Biochemical Characterization of WbpP, a New UDP-GlcNAc C4 Epimerase fromPseudomonas aeruginosaSerotype O6

     Article • Journal of Biological Chemistry, March 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

     Professor Warren Wakarchuk

120. 
     Ready Access to Sialylated Oligosaccharide Donors

     Article • Organic Letters, March 2000, American Chemical Society (ACS)

     Professor Warren Wakarchuk, Dennis M. Whitfield

121. 
     Functional genomics of Helicobacter pylori: identification of a beta-1,4 galactosyltransferase and generation of mutants with altered lipopolysaccharide

     Article • Molecular Microbiology, March 2000, Wiley

     Professor Warren Wakarchuk

122. 
     Biosynthesis of Ganglioside Mimics inCampylobacter jejuniOH4384

     Article • Journal of Biological Chemistry, February 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

     Professor Warren Wakarchuk

123. 
     Enzymatic Synthesis of Oligosaccharide Analogues:  Evaluation of UDP-Gal Analogues as Donors for Three Retaining α-Galactosyltransferases

     Article • Journal of the American Chemical Society, February 2000, American Chemical Society (ACS)

     Professor Warren Wakarchuk

124. 
     Glycosyl Fluorides Can Function as Substrates for Nucleotide Phosphosugar-dependent Glycosyltransferases

     Article • Journal of Biological Chemistry, December 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

     Professor Warren Wakarchuk

125. 
     Article • Glycoconjugate Journal, January 1999, Springer Science + Business Media

     Professor Warren Wakarchuk

126. 
     Article • Glycoconjugate Journal, January 1999, Springer Science + Business Media

     Professor Warren Wakarchuk

127. 
     The synthesis of sialylated oligosaccharides using a CMP-Neu5Ac synthetase/sialyltransferase fusion

     Article • Nature Biotechnology, August 1998, Springer Science + Business Media

     Professor Warren Wakarchuk

128. 
     Development of an on-line preconcentration method for the analysis of pathogenic lipopolysaccharides using capillary electrophoresis–electrospray mass spectrometry

     Article • Journal of Chromatography A, August 1998, Elsevier

     Professor Warren Wakarchuk

129. 
     Scan‐rate dependence in protein calorimetry: The reversible transitions of Bacillus circulans xylanase and a disulfide‐bridge mutant

     Article • Protein Science, July 1998, Wiley

     Professor Warren Wakarchuk

130. 
     Structure of an α‐2,6‐sialylated lipooligosaccharide from Neisseria meningitidis immunotype L1

     Article • FEBS Journal, June 1998, Wiley

     Professor Warren Wakarchuk

131. 
     Capsular polysaccharide synthesis in Streptococcus pneumoniae serotype 14: molecular analysis of the complete cps locus and identification of genes encoding glycosyltransferases required for the biosynthesis of the tetrasaccharide subunit

     Article • Molecular Microbiology, October 1997, Wiley

     Professor Warren Wakarchuk

132. 
     Characterization of a Recombinant Neisseria Meningitidesα‐2,3‐Sialyltransferase and its Acceptor Specificity

     Article • FEBS Journal, October 1997, Wiley

     Professor Warren Wakarchuk

133. 
     Positioning the Acid/Base Catalyst in a Glycosidase:  Studies with Bacillus circulans Xylanase

     Article • Biochemistry, February 1997, American Chemical Society (ACS)

     Professor Warren Wakarchuk

134. 
     Article • Biotechnology Letters, January 1997, Springer Science + Business Media

     Professor Warren Wakarchuk

135. 
     Cloning of the Lipooligosaccharide α-2,3-Sialyltransferase from the Bacterial PathogensNeisseria meningitidisandNeisseria gonorrhoeae

     Article • Journal of Biological Chemistry, November 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

     Professor Warren Wakarchuk, Professor Michael P Jennings

136. 
     Characterization of a buried neutral histidine residue inBacillus circulansxylanase: Nmr assignments, pH titration, and hydrogen exchange

     Article • Protein Science, November 1996, Wiley

     Professor Warren Wakarchuk

137. 
     Functional Relationships of the Genetic Locus Encoding the Glycosyltransferase Enzymes Involved in Expression of the Lacto-N-neotetraose Terminal Lipopolysaccharide Structure inNeisseria meningitidis

     Article • Journal of Biological Chemistry, August 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

     Professor Warren Wakarchuk, Professor Michael P Jennings

138. 
     Secondary structure and NMR assignments ofbacillus circulansxylanase

     Article • Protein Science, June 1996, Wiley

     Professor Warren Wakarchuk

139. 
     Effects of both Shortening and Lengthening the Active Site Nucleophile of Bacillus circulans Xylanase on Catalytic Activity

     Article • Biochemistry, January 1996, American Chemical Society (ACS)

     Professor Warren Wakarchuk

140. 
     The pKaof the General Acid/Base Carboxyl Group of a Glycosidase Cycles during Catalysis:  A13C-NMR Study ofBacillus circulansXylanase

     Article • Biochemistry, January 1996, American Chemical Society (ACS)

     Professor Warren Wakarchuk

141. 
     Abnormally High pKa of an Active‐Site Glutamic Acid Residue in Bacillus Circulans Xylanase

     Article • FEBS Journal, September 1995, Wiley

     Professor Warren Wakarchuk

142. 
     Expression of Trichoderma reesei and Trichoderma viride xylanases in Escherichia coli

     Article • Biochemistry and Cell Biology, May 1995, Canadian Science Publishing

     Professor Warren Wakarchuk

143. 
     Mutational and crystallographic analyses of the active site residues of the bacillus circulans xylanase

     Article • Protein Science, March 1994, Wiley

     Professor Warren Wakarchuk

144. 
     Thermostabilization of the Bacillus circulansxylanase by the introduction of disulfide bonds

     Article • Protein Engineering Design and Selection, January 1994, Oxford University Press (OUP)

     Professor Warren Wakarchuk

145. 
     Amino acid sequence and thermostability of xylanase A from schizophyllum commune

     Article • FEBS Letters, November 1993, Wiley

     Professor Warren Wakarchuk

146. 
     Overexpression of the Bacillus subtilis and circulans Xylanases in Escherichia coli

     Article • Protein Expression and Purification, June 1993, Elsevier

     Professor Warren Wakarchuk

147. 
     Two GC-rich DNA elements ofChlamydomonas reinhardtii with complex arrangements of directly repeated sequence motifs

     Article • Plant Molecular Biology, January 1992, Springer Science + Business Media

     Professor Warren Wakarchuk

148. 
     Gametic differentiation in Chlamydomonas reinhardtii: light dependence and gene expression patterns

     Article • Archives of Microbiology, November 1989, Springer Science + Business Media

     Professor Warren Wakarchuk

149. 
     The molecular cloning and expression of a cellobiase gene from anAgrobacterium inEscherichia coli

     Article • MGG Molecular & General Genetics, October 1986, Springer Science + Business Media

     Professor Warren Wakarchuk

150. 
     α-Putrescinylthymine and the sensitivity of bacteriophageφW-14 DNA to restriction endonucleases

     Article • Nucleic Acids Research, January 1985, Oxford University Press (OUP)

     Professor Warren Wakarchuk

151. 
     The Preliminary Characterization of the  -Glucosidases of Cellulomonas fimi

     Article • Microbiology, June 1984, Society for General Microbiology

     Professor Warren Wakarchuk

152. 
     The Cellulase System of Cellulomonas fimi

     Article • Microbiology, June 1984, Society for General Microbiology

     Professor Warren Wakarchuk

153. 
     Isolation and Characterization of Escherichia coli Clones Expressing Cellulase Genes from Cellulomonas fimi

     Article • Microbiology, June 1984, Society for General Microbiology

     Professor Warren Wakarchuk

154. 
     Capillary Electrophoresis as an Assay Method for Monitoring Glycosyltransferase Activity

     Article • Springer Science + Business Media

     Professor Warren Wakarchuk

155. 
     Analysis of Bacterial Glycolipids by Capillary Electrophoresis-Electrospray Mass Spectrometry: Haemophilus influenzae and Neisseria meningitidis Lipopolysaccharides

     Article • Springer Science + Business Media

     Professor Warren Wakarchuk