All Stories

  1. In vitro response of human ovarian cancer cells to dietary bioflavonoid isoquercitrin
  2. Isolated Silymarin Flavonoids Increase Systemic and Hepatic Bilirubin Concentrations and Lower Lipoperoxidation in Mice
  3. In-Cell Biochemistry Using NMR Spectroscopy
  4. Enzymatic oxidative dimerization of silymarin flavonolignans
  5. Access to bifunctionalized biomolecular platforms using oxime ligation
  6. Dehydro-flavonolignans from silymarin are potent inhibitors of lipid peroxidation in isolated respiring rat heart and liver mitochondria
  7. Isoquercitrin: Pharmacology, toxicology, and metabolism
  8. cis – trans Isomerization of silybins A and B
  9. Chemo-Enzymatic Synthesis of Silybin and 2,3-Dehydrosilybin Dimers
  10. Preparation of silybin phase II metabolites: Streptomyces catalyzed glucuronidation
  11. Inhibition of GlcNAc-Processing Glycosidases by C-6-Azido-NAG-Thiazoline and Its Derivatives
  12. Expression, characterization and homology modeling of a novel eukaryotic GH84 β-N-acetylglucosaminidase from Penicillium chrysogenum
  13. Biphasic Catalysis with Disaccharide Phosphorylases: Chemoenzymatic Synthesis of α-d-Glucosides Using Sucrose Phosphorylase
  14. Re-Evaluation of Binding Properties of Recombinant Lymphocyte Receptors NKR-P1A and CD69 to Chemically Synthesized Glycans and Peptides
  15. Chemistry of silybin
  16. Biotransformation of Silybin and its Congeners
  17. LC–MS metabolic study on quercetin and taxifolin galloyl esters using human hepatocytes as toxicity and biotransformation in vitro cell model
  18. Recombinant α-L-rhamnosidase ofAspergillus terreusimmobilization in polyvinylalcohol hydrogel and its application in rutin derhamnosylation
  19. Chemoenzymatic synthesis of α-l-rhamnosides using recombinant α-l-rhamnosidase from Aspergillus terreus
  20. Antioxidant, metal-binding and DNA-damaging properties of flavonolignans: A joint experimental and computational highlight based on 7-O-galloylsilybin
  21. Preparative Purification and Isolation of Pyranoanthocyanins from Red Wine and Evaluation of Their Antioxidant Activity
  22. ChemInform Abstract: Enzymatic Glycosylation of Multivalent Scaffolds
  23. Effect of 3-O-Galloyl Substitution on the Electrochemical Oxidation of Quercetin and Silybin Galloyl Esters at Glassy Carbon Electrode
  24. Preparation of silybin and isosilybin sulfates by sulfotransferase from Desulfitobacterium hafniense
  25. Bioavailability of silymarin flavonolignans: drug formulations and biotransformation
  26. Anti-Cancer Efficacy of Silybin Derivatives - A Structure-Activity Relationship
  27. Enzymatic preparation of silybin phase II metabolites: sulfation using aryl sulfotransferase from rat liver
  28. Enzymatic synthesis of new C-6-acylated derivatives of NAG-thiazoline and evaluation of their inhibitor activities towards fungal β-N-acetylhexosaminidase
  29. A Novel Semisynthetic Flavonoid 7-O-Galloyltaxifolin Upregulates Heme Oxygenase-1 in RAW264.7 Cells via MAPK/Nrf2 Pathway
  30. ChemInform Abstract: Enzymatic Glycosylation of Small Molecules: Challenging Substrates Require Tailored Catalysts
  31. Enzymatic glycosylation of multivalent scaffolds
  32. β‐N‐Acetylhexosaminidases: group‐specific inhibitors wanted
  33. Preparative method for isosilybin isolation based on enzymatic kinetic resolution of silymarin mixture
  34. Ionic liquids as cosolvents for glycosylation by sucrose phosphorylase: balancing acceptor solubility and enzyme stability
  35. Base-catalyzed oxidation of silybin and isosilybin into 2,3-dehydro derivatives
  36. Production of Aspergillus niger β-mannosidase in Pichia pastoris
  37. Enzymatic Glycosylation of Small Molecules: Challenging Substrates Require Tailored Catalysts
  38. Preparatory production of quercetin-3-β-d-glucopyranoside using alkali-tolerant thermostable α-l-rhamnosidase from Aspergillus terreus
  39. Biotransformation of flavonols and taxifolin in hepatocyte in vitro systems as determined by liquid chromatography with various stationary phases and electrospray ionization-quadrupole time-of-flight mass spectrometry
  40. Chemo-enzymatic modification of poly- N -acetyllactosamine (LacNAc) oligomers and N,N -diacetyllactosamine (LacDiNAc) based on galactose oxidase treatment
  41. Recombinant α-l-rhamnosidase from Aspergillus terreus in selective trimming of rutin
  42. Facile synthesis of nitrophenyl 2-acetamido-2-deoxy-α-D-mannopyranosides from ManNAc-oxazoline
  43. Quercetin, Quercetin Glycosides and Taxifolin Differ in their Ability to Induce AhR Activation and CYP1A1 Expression in HepG2 Cells
  44. Heterologous Expression and Characterization of an N-Acetyl-β-d-hexosaminidase from Lactococcus lactis ssp. lactis IL1403
  45. Sequencing, cloning and high-yield expression of a fungal β-N-acetylhexosaminidase in Pichia pastoris
  46. Facile production of Aspergillus niger α-N-acetylgalactosaminidase in yeast
  47. Flavonoid-dependent Attenuation of Mitochondrial ROS Formation is Augmented by Their Modulation of Bioenergetic Status of the Cell
  48. Synthesis and Antiangiogenic Activity of New Silybin Galloyl Esters
  49. Electrochemical investigation of flavonolignans and study of their interactions with DNA in the presence of Cu(II)
  50. Laboratory evolution of an epoxide hydrolase – Towards an enantioconvergent biocatalyst
  51. Biodegradation of tetrabromobisphenol A by oxidases in basidiomycetous fungi and estrogenic activity of the biotransformation products
  52. ChemInform Abstract: Glycosidases in Carbohydrate Synthesis: When Organic Chemistry Falls Short
  53. Purification and characterization of heterologously expressed nitrilases from filamentous fungi
  54. Combinatorial One-Pot Synthesis of Poly-N-acetyllactosamine Oligosaccharides with Leloir-Glycosyltransferases
  55. Regioselective alcoholysis of silybin A and B acetates with lipases
  56. Charged Hexosaminides as New Substrates for β-N-Acetylhexosaminidase-Catalyzed Synthesis of Immunomodulatory Disaccharides
  57. Study of electrooxidation mechanisms and antioxidant properties of flavonols and flavonolignans
  58. Narrow-bore core-shell particles and monolithic columns in the analysis of silybin diastereoisomers
  59. Enzymatic characterization and molecular modeling of an evolutionarily interesting fungal β‐N‐acetylhexosaminidase
  60. Evidence for differences in regioselective and stereoselective glucuronidation of silybin diastereomers from milk thistle (Silybum marianum) by human UDP-glucuronosyltransferases
  61. Dimerisation Process of Silybin-Type Flavonolignans: Insights from Theory
  62. Glycosidases in Carbohydrate Synthesis: When Organic Chemistry Falls Short
  63. Dendri-RAFTs: a second generation of cyclopeptide-based glycoclusters
  64. Dehydrosilybin attenuates the production of ROS in rat cardiomyocyte mitochondria with an uncoupler-like mechanism
  65. Analysis of anthocyanin pigments in Lonicera (Caerulea) extracts using chromatographic fractionation followed by microcolumn liquid chromatography-mass spectrometry
  66. β-N-Acetylhexosaminidase: What's in a name…?
  67. Large-scale separation of silybin diastereoisomers using lipases
  68. Genome mining for the discovery of new nitrilases in filamentous fungi
  69. Azido leaving group in enzymatic synthesis-small and efficient
  70. Synthesis and biological activity of glycosyl-1H-1,2,3-triazoles
  71. Cardioprotective activity of dehydrosilybin is linked to its uncoupler-like behavior
  72. Effect of flavonolignans derived from silybin on mitochondrial production of reactive oxygen species
  73. ChemInform Abstract: Enzymatic Glycosylation of Branched Symmetrical Non-Carbohydrate Polyols.
  74. ChemInform Abstract: Enzymatic Synthesis of p-Nitrophenyl β-Chitobioside.
  75. ChemInform Abstract: Enzymatic Glycosylation Using 6-O-Acylated Sugar Donors and Acceptors: β-N-Acetylhexosaminidase-Catalyzed Synthesis of 6-O,N,N′-Triacetylchitobiose (III) and 6′-O,N,N′-Triacetylchitobiose (VI).
  76. ChemInform Abstract: Selective Biotransformation of Substituted Alicyclic Nitriles by Rhodococcus equi A4.
  77. Biotransformations with nitrilases
  78. Antioxidant and antiviral activities of silybin fatty acid conjugates
  79. ChemInform Abstract: Glycosidases in Synthesis
  80. Enzymatic Processing of Bioactive Glycosides from Natural Sources
  81. Condensation reactions catalyzed by α-N-acetylgalactosaminidase fromAspergillus nigeryielding α-N-acetylgalactosaminides
  82. Silybin Derivatives Modulate Thyroid Hormone-Mediated UcP2 Expression in Neonatal Rat Cardiomyocytes
  83. Chemoenzymatic preparative separation of silybins A and B
  84. Silybin (Silibinin) Structure and Chirality
  85. Fungal nitrilases as biocatalysts: Recent developments
  86. Glycosidases in synthesis
  87. Glycosidases: a key to tailored carbohydrates
  88. Silibinin chirality
  89. Molecular mechanisms of silybin and 2,3-dehydrosilybin antiradical activity—role of individual hydroxyl groups
  90. α-Galactosidases and their applications in biotransformations
  91. Enzymatic preparation of acylated derivatives of silybin in organic and ionic liquid media and evaluation of their antitumor proliferative activity
  92. Biodegradation potential of the genus Rhodococcus
  93. Chemo-enzymatic synthesis of poly-N-acetyllactosamine (poly-LacNAc) structures and their characterization for CGL2-galectin-mediated binding of ECM glycoproteins to biomaterial surfaces
  94. Maca (Lepidium meyenii) and yacon (Smallanthus sonchifolius) in combination with silymarin as food supplements: In vivo safety assessment
  95. Selection and screening for enzymes of nitrile metabolism
  96. Laccase-mediated dimerization of the flavonolignan silybin
  97. Biotransformation of nitriles to amides using soluble and immobilized nitrile hydratase from Rhodococcus erythropolis A4
  98. Mechanism of the Antioxidant Action of Silybin and 2,3-Dehydrosilybin Flavonolignans: A Joint Experimental and Theoretical Study
  99. Glycoside vs. Aglycon: The Role of Glycosidic Residue in Biological Activity
  100. Studies on oxidation of ergot alkaloids: oxidation and desaturation of dihydrolysergol—stereochemical requirements
  101. Structure, Function and Dynamics of fungal β-N-Hexosaminidase
  102. Structural modeling of alpha-galactosidase and alpha-galactosaminidase from Aspergillus Niger
  103. New aldoxime-dehydrating enzymes from filamentous fungi
  104. Glycosyl Azides – An Alternative Way to Disaccharides
  105. Structure of the dimeric N-glycosylated form of fungal β-N-acetylhexosaminidase revealed by computer modeling, vibrational spectroscopy, and biochemical studies
  106. Biotransformation of heterocyclic dinitriles by Rhodococcus erythropolis and fungal nitrilases
  107. Large Propeptides of Fungal β-N-Acetylhexosaminidases Are Novel Enzyme Regulators That Must Be Intracellularly Processed to Control Activity, Dimerization, and Secretion into the Extracellular Environment
  108. Silybin and Silymarin - New and Emerging Applications in Medicine
  109. Induction and characterization of an unusual α-d-galactosidase from Talaromyces flavus
  110. Extension of the Nef reaction to C-glycosylnitromethanes
  111. Cyanodeoxy-Glycosyl Derivatives as Substrates for Enzymatic Reactions
  112. Preparative production and separation of 2-acetamido-2-deoxymannopyranoside-containing saccharides using borate-saturated polyolic exclusion gels
  113. New derivatives of silybin and 2,3-dehydrosilybin and their cytotoxic and P-glycoprotein modulatory activity
  114. Unique transglycosylation potential of extracellular α-d-galactosidase from Talaromyces flavus
  115. β-1,4-Galactosyltransferase-catalyzed glycosylation of sugar derivatives: Modulation of the enzyme activity by α-lactalbumin, immobilization and solvent tolerance
  116. Cyanodeoxy‐Glycosyl Derivatives as Substrates for Enzymatic Reactions
  117. Immobilization of fungal nitrilase and bacterial amidase – two enzymes working in accord
  118. Glycosyl azide—a novel substrate for enzymatic transglycosylations
  119. Effects of silymarin flavonolignans and synthetic silybin derivatives on estrogen and aryl hydrocarbon receptor activation
  120. Silybin and silymarin - new effects and applications
  121. The efficacy of glucosamine and chondroitin sulfate in the treatment of osteoarthritis: are these saccharides drugs or nutraceuticals?
  122. Biocatalyzed Generation of Molecular Diversity: Selective Modification of the Saponin Asiaticoside
  123. Combined Application of Galactose Oxidase and β-N-Acetylhexosaminidase in the Synthesis of Complex ImmunoactiveN-Acetyl-D-galactosaminides
  124. A chemoenzymatic route to mannosamine derivatives bearing different N-acyl groups
  125. Screening and characterization of β-N-acetylhexosaminidases for the synthesis of nucleotide-activated disaccharides
  126. Synthesis of 4-Nitrophenyl 2-Acetamido-2-deoxy-β-D-mannopyranoside and 4-Nitrophenyl 2-Acetamido-2-deoxy-α-D-mannopyranoside.
  127. Enzymatic Discrimination of 2-Acetamido-2-deoxy-D-mannopyranose-Containing Disaccharides Using β-N-Acetylhexosaminidases
  128. Chemical Biology and Biomedicine of Glycosylated Natural Compounds
  129. Synthesis of 4-Nitrophenyl 2-Acetamido-2-deoxy-β-D-mannopyranoside and 4-Nitrophenyl 2-Acetamido-2-deoxy-α-D-mannopyranoside
  130. Selective biotransformation of substituted alicyclic nitriles by Rhodococcus equi A4
  131. p-NITROPHENYL 2-AZIDO-2-DEOXY-D-HEXOPYRANOSIDES AS DONORS FOR ENZYMIC GLYCOSYLATION
  132. Nitrile- and Amide-converting Microbial Enzymes: Stereo-, Regio- and Chemoselectivity
  133. Exploitation of a library of ?-galactosidases for the synthesis of building blocks for glycopolymers
  134. Glycosides in Medicine: “The Role of Glycosidic Residue in Biological Activity”
  135. Chemical Biology and Biomedicine of Glycosylated Natural Compounds
  136. Semisynthetic Dimers of Antiparkinsonic Ergot Alkaloids
  137. Enzymatic Glycosylation of Lincomycin
  138. Silymarin: What is in the name …? An appeal for a change of editorial policy
  139. ChemInform Abstract: Enzymatic Preparation of Lysergol β‐D‐Glucuronide.
  140. ChemInform Abstract: One‐pot Enzymatic Synthesis of Sialyl T‐Epitope
  141. Formation ofmyo-inositol phosphates byAspergillus niger 3-phytase
  142. ChemInform Abstract: Pyridoxine as a Substrate for Screening Synthetic Potential of Glycosidases.
  143. Enzymatic Preparation of Lysergol β-D-Glucuronide
  144. Enzymatic synthesis of iso-globotriose from partially protected lactose
  145. Agroclavine Glycosylation
  146. One-Pot Enzymatic Synthesis of Sialyl T-Epitope
  147. Pyridoxine as a Substrate for Screening Synthetic Potential of Glycosidases
  148. Enzymatic Synthesis ofP-Nitrophenyl β-Chitobioside
  149. Unusual nonreducing sugar GlcNAcβ(1↔1)Manβ formation by β-N-acetylhexosaminidase from Aspergillus oryzae
  150. Enzymatic Glycosylation of Branched Symmetrical Non-Carbohydrate Polyols
  151. Glycosidase-Catalysed Synthesis of Ergot Alkaloid α-Glycosides
  152. Effect ofp-Substitution of Aryl α-D-Mannosides on Inhibiting Mannose-Sensitive Adhesion ofEscherichia coli – Syntheses and Testing
  153. Glucosylation of silybin by plant cell cultures of Papaver somniferum var. setigerum
  154. Transglycosylation of Thiamin by Fungal β-N-Acetylhexosaminidases
  155. β-Glucosylation of chitooligomers by galactosyltransferase
  156. Biotransformation of Ergot Alkaloids by Haloperoxidase fromStreptomyces aureofaciens: Stereoselective Acetoxylation and Propionoxylation
  157. N -Deoxyribosides of ergot alkaloids: Synthesis and biological activity
  158. Enzymatic and chemical glycosylations of ergot alkaloids and biological aspects of new compounds
  159. Synthesis and Antiviral Evaluation of N-β-D-Ribosides of Ergot Alkaloids
  160. Glycosylation of silybin
  161. Sterols and fatty acids in Peziza muralis
  162. Ergot alkaloid glycosides with immunomodulatory activities
  163. Biotransformations of γ-methyl-β-ketosulfones: stereoselectivity of 3-methyl-1-(phenylsulfonyl)hexan-2-one reductions by various yeasts
  164. N-1-Trimethylsilyl Derivatives of Ergot Alkaloids
  165. Biotransformation of Chanoclavine by Euphorbia calyptrata Cell Culture
  166. Dimerization of Lysergene by Euphorbia calyptrata Cell Cultures
  167. Biotransformations of aromatic diniitriles using Rhodococcus equi cells
  168. A Multienzyme System for a One-Pot Synthesis of Sialyl T-Antigen
  169. Ein Multienzymsystem zur Eintopfsynthese des Sialyl‐T‐Antigens
  170. Assignment of Nitrogen Stereochemistry of Agroclavine and Elymoclavine 6-N-Oxides
  171. Synthesis of α-mannosylated ergot alkaloids employing α-mannosidase
  172. Fast atom bombardment mass spectrometry of elymoclavine glycosides
  173. Claviceps purpurea (Ergot): Culture and Bioproduction of Ergot Alkaloids
  174. Determination of Lovastatin (mevinolin) and mevinolinic acid in fermentation liquids
  175. Fructosylation of ergot alkaloids by yeast invertase
  176. Galactose oxidase production by immobilized cells ofDactylium dendroides
  177. Bioconversions of ergot alkaloids
  178. Glycosylation of ergot alkaloids by free and immobilized cells of Claviceps purpurea
  179. Effect of triadimefon on lipids, sterols, and membrane fluidity in submerged cultures of claviceps purpurea
  180. Physiological control and process kinetics of clavine alkaloid production byClaviceps purpurea
  181. Physiological control and process kinetics of clavine alkaloid production byClaviceps purpurea
  182. Effect of clomiphene on fatty acids, sterols and membrane fluidity in clavine producing claviceps purpurea strains
  183. Physiological activity of immobilized cells of Claviceps fusiformis during long-term semicontinuous cultivation
  184. Effect of cultivation temperature, clomiphene, and nystatin on the oxidation and cyclization of chanoclavine in submerged cultures of the mutant strainclaviceps purpurea 59
  185. High-production mutant Claviceps purpurea 59 accumulating secoclavines
  186. Identification of fatty acids in submerged cultures of Claviceps species
  187. Occurrence of ricinoleic acid in submerged cultures of variousClaviceps sp.
  188. Continuous cultivation ofCandida utilis yeasts growing on calcium bisulphite waste liquors