All Stories

  1. Synthesis, Characterization, Antimicrobial and Anticancer Studies of Metal Complexes of 2-methoxy-4-((3-methylpyridin-2-ylimino)methyl)phenol
  2. Cytotoxicity of Anchusa arvensis Against HepG-2 Cell Lines: Mechanistic and Computational Approaches
  3. In Silico, Cytotoxic and Antioxidant Potential of Novel Ester, 3-hydroxyoctyl -5- trans-docosenoate Isolated from Anchusa arvensis (L.) M.Bieb. Against HepG-2 Cancer Cells
  4. Synthesis of novel N-(1,3-thiazol-2-yl)benzamide clubbed oxadiazole scaffolds: Urease inhibition, Lipinski rule and molecular docking analyses
  5. Bi-heterocyclic benzamides as alkaline phosphatase inhibitors: Mechanistic comprehensions through kinetics and computational approaches
  6. Design, Synthesis and Therapeutic Potential of some 6, 6`-(1,4-phenylene)bis(4-(4-bromophenyl)pyrimidin-2-amine)analogues
  7. Synthesis of acetamide derivatives of 1,2,4-triazole bearing azinane and their binding interactions with bovine serum albumin using spectroscopic techniques
  8. Synthesis and biological profile of substituted benzimidazoles
  9. 2-Furoic piperazide derivatives as promising drug candidates of type 2 diabetes and Alzheimer’s diseases: In vitro and in silico studies
  10. Design, synthesis and biological evaluation of 3-(2-aminooxazol-5-yl)-2H-chromen-2-one derivatives
  11. Design, synthesis and therapeutic potential of 3-(2-(1H-benzo[d]imidazol-2-ylthio)acetamido)-N-(substituted phenyl)benzamide analogues
  12. Exploration of synthetic multifunctional amides as new therapeutic agents for Alzheimer's disease through enzyme inhibition, chemoinformatic properties, molecular docking and dynamic simulation insights
  13. Isolation and characterization of novel antibacterial compound from an untapped plant, Stereospermum fimbriatum
  14. Synthesis, biological evaluation and corrosion inhibition studies of transition metal complexes of Schiff base
  15. Reverse pharmacophore mapping and molecular docking studies for discovery of GTPase HRas as promising drug target for bis-pyrimidine derivatives
  16. Antiradical and Xanthine Oxidase Inhibitory Activity Evaluations of Averrhoa bilimbi L. Leaves and Tentative Identification of Bioactive Constituents through LC-QTOF-MS/MS and Molecular Docking Approach
  17. Design, synthesis and biological potential of heterocyclic benzoxazole scaffolds as promising antimicrobial and anticancer agents
  18. Design, Synthesis, SAR Study, Antimicrobial and Anticancer Evaluation of Novel 2-Mercaptobenzimidazole Azomethine Derivatives
  19. Synthesis, SAR elucidations and molecular docking study of newly designed isatin based oxadiazole analogs as potent inhibitors of thymidine phosphorylase
  20. Benzoxazole derivatives: design, synthesis and biological evaluation
  21. Synthesis of 3-[4-(2-furoyl)-1-piperazinyl]-N- (substituted)propanamides as promising antibacterial agents with mild cytotoxicity
  22. Norditerpenoid alkaloids of Delphinium denudatum as cholinesterase inhibitors
  23. Synthesis, molecular docking study and in vitro thymidine phosphorylase inhibitory potential of oxadiazole derivatives
  24. Investigation of 3-formylcoumarin derivatives
  25. Synthesis of some new propanamide derivatives bearing 4- piperidinyl-1,3,4-oxadiazole, and their evaluation as promising anticancer agents
  26. Synthesis, in vitro and in silico studies of novel potent urease inhibitors: N -[4-({5-[(3-Un/substituted-anilino-3-oxopropyl)sulfanyl]-1,3,4-oxadiazol-2-yl}methyl)-1,3-thiazol-2-yl]benzamides
  27. Synthesis, enzyme inhibitory kinetics mechanism and computational study of N-(4-methoxyphenethyl)-N-(substituted)-4-methylbenzenesulfonamides as novel therapeutic agents for Alzheimer’s disease
  28. Synthesis of 2-{[5-(aralkyl/aryl)-1,3,4-oxadiazol-2- yl]sulfanyl}-N-(4-methyl-1,3-thiazol-2-yl)acetamides: Novel bi-heterocycles as potential therapeutic agents
  29. S -substituted derivatives of 1,2,4-triazol-3-thiol as new drug candidates for type II diabetes
  30. Synthesis and evaluation of antimicrobial, antitubercular and anticancer activities of 2-(1-benzoyl-1H-benzo[d]imidazol-2-ylthio)-N-substituted acetamides
  31. Synthesis of new heterocyclic 3-piperidinyl-1,3,4-oxadiazole derivatives as potential drug candidate for the treatment of Alzheimer’s disease
  32. Neuroprotective effects of Foeniculum vulgare seeds extract on lead-induced neurotoxicity in mice brain
  33. Phytoconstituents from Vernonia glaberrima Welw. Ex O. Hoffm. leaves and their cytotoxic activities on a panel of human cancer cell lines
  34. Synthesis, α-glucosidase inhibition and molecular docking study of coumarin based derivatives
  35. Design, synthesis and cytotoxic effects of curcuminoids on HeLa, K562, MCF-7 and MDA-MB-231 cancer cell lines
  36. Studies of Flavokawain B Type Chalcones and their Cytotoxic Effects
  37. Compounds with 1,3,4-oxadiazole and azinane appendages to evaluate enzymes inhibition applications supported by docking and BSA binding
  38. A new sulphated flavone and other phytoconstituents from the leaves of Tetracera indica Merr. and their alpha-glucosidase inhibitory activity
  39. Protective effects of Nigella sativa L. seed extract on lead induced neurotoxicity during development and early life in mouse models
  40. Novel indole based hybrid oxadiazole scaffolds with N-(substituted-phenyl)butanamides: synthesis, lineweaver–burk plot evaluation and binding analysis of potent urease inhibitors
  41. Synthesis and Structural Analysis of Persuasive Antibacterial Agents and Enzyme Inhibitors Derived from 5-(1-(4-Tosyl)piperidin-4-yl)-1,3,4-oxadiazol-2-thiol
  42. Syzygium aromaticum ethanol extract reduces AlCl3-induced neurotoxicity in mice brain through regulation of amyloid precursor protein and oxidative stress gene expression
  43. Synthesis and in vitro study of benzofuran hydrazone derivatives as novel alpha-amylase inhibitor
  44. Synthesis, characterization, biological evaluation and molecular docking studies of 2-(1H-benzo[d]imidazol-2-ylthio)-N-(substituted 4-oxothiazolidin-3-yl) acetamides
  45. Synthesis, molecular docking and biological evaluation of bis-pyrimidine Schiff base derivatives
  46. Pharmacological Effects of Turmeric on Learning, Memory and Expression of Muscarinic Receptor Genes (M1, M3 and M5) in Stress-induced Mouse Model
  47. Bis-pyrimidine acetamides: design, synthesis and biological evaluation
  48. Synthesis of a series of new 6-Nitrobenzofuran-2-carbohydrazide derivatives with cytotoxic and antioxidant activity
  49. Antioxidant and anticholinesterase potential of diterpenoid alkaloids from Aconitum heterophyllum
  50. Synthesis and molecular docking of new hydrazones derived from ethyl isonipecotate and their biological activities
  51. Selective dual cholinesterase inhibitors from Aconitum laeve
  52. Diazenyl schiff bases: Synthesis, spectral analysis, antimicrobial studies and cytotoxic activity on human colorectal carcinoma cell line (HCT-116)
  53. Synthesis and pharmacological screening: Sulfa derivatives of 2-pipecoline-bearing 1,3,4-oxadiazole core
  54. Synthesis, Antibacterial and Lipoxygenase Inhibition Studies of N-(Alkyl/aralkyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-methylbenzenesulfonamides
  55. Synthesis of Some Unique Carbamate Derivatives bearing 2-Furoyl-1-piperazine as Valuable Therapeutic Agents
  56. Synthesis of N-substituted acetamide derivatives of azinane-bearing 1,3,4-oxadiazole nucleus and screening for antibacterial activity
  57. Morpholine hydrazone scaffold: Synthesis, anticancer activity and docking studies
  58. Synthesis and in silico study of 2-furyl(4-{4-[(substituted)sulfonyl]benzyl}-1-piperazinyl)methanone derivatives as suitable therapeutic agents
  59. Synthesis, Multiparametric Structure Assessment and Biological Evaluation of Some New 1,3,4-Oxadiazoles Containing Piperidine Nucleus
  60. Acyclovir-Polyethylene Glycol 6000 Binary Dispersions: Mechanistic Insights
  62. Crystal structure, phytochemical study and enzyme inhibition activity of Ajaconine and Delectinine
  63. Green synthesis of silver nanoparticles using Atrocarpus altilis leaf extract and the study of their antimicrobial and antioxidant activity
  64. Synthesis, spectral analysis and pharmacological study of N'- substituted-2-(5-((2,4-dimethylphenoxy)methyl)-1,3,4-oxadiazol-2-ylthio)acetohydrazides
  65. Synthesis and antibacterial profile of novel azomethine derivatives of β-phenylacrolein moiety
  66. Synthesis, Characterization, Antibacterial, α-Glucosidase Inhibition and Hemolytic Studies on Some New N-(2,3- Dimethylphenyl)benzenesulfonamide Derivatives
  67. simvastatin solubility enhancement
  68. Synthesis of some new N-substituted-N-(2,3-Dihydro-[1,4]benzodioxin-6-yl)-4-acetamidobenzenesulfonamides as valuable antibacterial agents
  70. Antiglycation and antioxidant potential of novel imidazo[4,5-b]pyridine benzohydrazones
  71. Synthesis of novel derivatives of oxindole, their urease inhibition and molecular docking studies
  72. Synthesis of 3,4,5-trihydroxybenzohydrazone and evaluation of their urease inhibition potential
  73. Design and synthesis of chalcone derivatives as potent tyrosinase inhibitors and their structural activity relationship
  74. Neuroprotective effect from stem bark extracts ofKnema laurinaagainst H2O2- and Aβ1–42-induced cell death in human SH-SY5Y cells
  75. Crystal structure of 2-{[1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yloxy]carbonyl}benzoic acid
  76. Structure and Absolute Configuration of 20β-Hydroxyprednisolone, a Biotransformed Product of Predinisolone by the Marine Endophytic Fungus Penicilium lapidosum
  77. Microbial-Catalyzed Biotransformation of Multifunctional Triterpenoids Derived from Phytonutrients
  78. Phenoxyacetohydrazide Schiff Bases: β-Glucuronidase Inhibitors
  79. (E)-3-Chloro-N′-(2-fluorobenzylidene)thiophene-2-carbohydrazide
  80. Antioxidant Activity of Hispidin Oligomers from Medicinal Fungi: A DFT Study
  81. 2-{[2-(2-Hydroxy-5-methoxybenzylidene)hydrazin-1-ylidene]methyl}-4-methoxyphenol
  82. Microbial Transformation of Bioactive Anthraquinones ? A Review
  83. Prenylated Xanthone and Rubraxanthone with Antiplatelet Aggregation Activity in Human Whole Blood Isolated from Garcinia griffithii
  84. Biotransformation of 17α-ethynyl substituted steroidal drugs with microbial and plant cell cultures: A review
  85. Antiplatelet Aggregation Activity of 5-Hydroxyflavone, 2’- Hydroxyflavanone, Paeonol and Bergenin Isolated from Stem Bark of Garcinia malaccensis in Human Whole Blood
  86. A Whole-cell Biocatalysis Application of Steroidal Drugs
  87. Solute Solvent Interactions of Polyvinyl Pyrrolidone Wrapped Single Walled Carbon Nanotubes (PVP-SWNTs) in Water by Viscometric Studies
  88. Biotransformation of tissue-specific hormone tibolone with fungal culture Trichothecium roseum
  89. (E)-N′-(4-Chlorobenzylidene)-2-methoxybenzohydrazide
  90. (E)-2-Methoxy-N′-(2,4,6-trihydroxybenzylidene)benzohydrazide
  91. 3-[2-(Triphenylphosphanylidene)acetyl]-2H-chromen-2-one
  92. N′-[(E)-2,3-Dihydroxybenzylidene]-2-methoxybenzohydrazide
  93. N′-[(E)-2-Hydroxy-5-methoxybenzylidene]-2-methoxybenzohydrazide
  94. Synthesis of 1,3,6-Trioxygenated Prenylated Xanthone Derivatives as Potential Antitumor Agents
  95. Protective effects of total alkaloidal extract from Murraya koenigii leaves on experimentally induced dementia
  96. Synthesis and SAR Study of Prenylated Xanthone Analogues as HeLa and MDA-MB-231 Cancer Cell Inhibitors
  97. New class of acetylcholinesterase inhibitors from the stem bark of Knema laurina and their structural insights
  98. Molecular docking studies of potent inhibitors of tyrosinase and α-glucosidase
  99. Phytochemical and Cytotoxic Investigations of Curcuma mangga Rhizomes
  101. Microbial oxidation of anabolic steroids
  102. Microbial transformation of oleanolic acid byFusarium liniandα-glucosidase inhibitory activity of its transformed products
  103. Structure and dynamics of the hydrated palladium(II) ion in aqueous solution A QMCF MD simulation and EXAFS spectroscopic study
  104. Science at the interface of chemistry and biology: Discoveries of α-glucosidase inhibitors and antiglycation agents
  105. A QM/MM MD simulation study of hydrated Pd2+
  106. Biotransformation of Physalin H and Leishmanicidal Activity of Its Transformed Products
  107. Fungal Metabolites of (E)-Guggulsterone and Their Antibacterial and Radical-Scavenging Activities
  108. Microbial Hydroxylation of Pregnenolone Derivatives
  109. Microbial Transformation of Dehydroepiandrosterone