All Stories

  1. Oral bisphosphonates and risk of incident osteoarthritis in individuals with osteoporosis: a target trial emulation

    Article • RMD Open, April 2026, BMJ

    Dr. Sakae Tanaka

  2. Randomized crossover comparison of two teriparatide self-injection regimens for primary osteoporosis: final report of the Japanese Osteoporosis Intervention Trial 06 (JOINT-06)

    Article • Journal of Bone and Mineral Metabolism, September 2025, Springer Science + Business Media

    Dr. Sakae Tanaka

  3. AI‐Powered Smartphone Application for Measuring Hallux Valgus Angle From Radiographs Displayed on a Monitor

    Article • Journal of Foot and Ankle Research, September 2025, Wiley

    Dr. Sakae Tanaka

  4. Sodium-glucose co-transporter-2 inhibitors versus metformin in reducing osteoarthritis risk: A retrospective cohort study of health insurance claims and check-up data

    Article • JBMR Plus, August 2025, Oxford University Press (OUP)

    Dr. Sakae Tanaka

  5. Long-term follow-up study of Kudo type-5 elbow prosthesis in patients with rheumatoid arthritis: minimum 10-year clinical outcomes

    Article • Journal of Shoulder and Elbow Surgery, July 2025, Elsevier

    Dr. Sakae Tanaka

  6. Ganglion Formation After Steroid Injection for Stenosing Flexor Tenosynovitis

    Article • JBJS Open Access, July 2025, Wolters Kluwer Health

    Dr. Sakae Tanaka

  7. PHEX Protein in the Parathyroid Gland Contributes to Phosphate Sensing

    Article • The Journal of Clinical Endocrinology & Metabolism, June 2025, Endocrine Society

    Dr. Sakae Tanaka

  8. Incidence, risk factors, and prognostic impact of regional lymph node metastasis in bone sarcoma: a population-based cohort study

    Article • Japanese Journal of Clinical Oncology, June 2025, Oxford University Press (OUP)

    Dr. Sakae Tanaka

  9. Impact of postoperative nutritional status on the patients’ clinical outcomes and knee biomechanics following total knee arthroplasty in Japan: a prospective cohort study

    Article • Annals of Clinical Nutrition and Metabolism, April 2025, Korean Society for Parenteral and Enteral Nutrition

    Dr. Sakae Tanaka

  10. Gout incidence in metformin versus sodium–glucose co-transporter-2 inhibitor users: a retrospective cohort study

    Article • Rheumatology, March 2025, Oxford University Press (OUP)

    Dr. Sakae Tanaka

  11. Urinary 4-pyridoxic acid as a non-invasive biomarker for evaluating osteoarthritis severity: findings from the ROAD study

    Article • Aging Clinical and Experimental Research, February 2025, Springer Science + Business Media

    Dr. Sakae Tanaka

  12. Successful treatment of recurrent haemarthrosis after total knee arthroplasty using genicular artery embolisation in a patient with rheumatoid arthritis

    Article • Modern Rheumatology Case Reports, January 2025, Oxford University Press (OUP)

    Dr. Sakae Tanaka

  13. Anti-osteoporotic drug efficacy for periprosthetic bone loss after total hip arthroplasty: A systematic review and network meta-analysis

    Article • Journal of Orthopaedic Science, January 2025, Elsevier

    Dr. Sakae Tanaka

  14. Detection of Chronic Musculoskeletal Pain Using Voice Characteristics

    Article • IEEE Journal of Translational Engineering in Health and Medicine, January 2025, Institute of Electrical & Electronics Engineers (IEEE)

    Dr. Sakae Tanaka

  15. Multiple insular-prefrontal pathways underlie perception to execution during response inhibition in humans

    Article • Nature Communications, December 2024, Springer Science + Business Media

    Dr. Sakae Tanaka

  16. Fibroma of Tendon Sheath Arising in the Subacromial Bursa

    Article • JBJS Essential Surgical Techniques, October 2024, Wolters Kluwer Health

    Dr. Sakae Tanaka

  17. Increased early complications after total hip arthroplasty compared with hemiarthroplasty in older adults with a femoral neck fracture

    Article • The Bone & Joint Journal, September 2024, Bone & Joint

    Dr. Sakae Tanaka

  18. Outcomes after hip fracture surgery in patients receiving non-steroidal anti-inflammatory drugs alone, acetaminophen alone, or both

    Article • The Bone & Joint Journal, August 2024, Bone & Joint

    Dr. Sakae Tanaka

  19. Factors associated with work sustainability in patients with bone metastasis

    Article • Japanese Journal of Clinical Oncology, June 2024, Oxford University Press (OUP)

    Dr. Sakae Tanaka

  20. Embryonal and alveolar rhabdomyosarcoma in adolescents/young adults, adults and older adults: a population-based cohort study

    Article • Japanese Journal of Clinical Oncology, April 2024, Oxford University Press (OUP)

    Dr. Sakae Tanaka

  21. Extended curettage for tumour-induced osteomalacia in the bone

    Article • Japanese Journal of Clinical Oncology, January 2024, Oxford University Press (OUP)

    Dr. Sakae Tanaka

  22. Prognostic factors and treatment outcomes in patients with pleomorphic rhabdomyosarcoma: a population-based cohort study

    Article • Japanese Journal of Clinical Oncology, January 2024, Oxford University Press (OUP)

    Dr. Sakae Tanaka

  23. Aging effects on osteoclast progenitor dynamics affect variability in bone turnover via feedback regulation

    Article • JBMR Plus, January 2024, Oxford University Press (OUP)

    Dr. Sakae Tanaka

  24. Irreversible covalent Bruton's tyrosine kinase inhibitor, TAS5315 versus placebo in rheumatoid arthritis patients with inadequate response to methotrexate: a randomised, double-blind, phase IIa trial

    Article • Annals of the Rheumatic Diseases, August 2023, Elsevier

    Dr. Sakae Tanaka

  25. Changes in knee joint destruction patterns among patients with rheumatoid arthritis undergoing total knee arthroplasty in recent decades

    Article • Clinical Rheumatology, May 2023, Springer Science + Business Media

    Dr. Sakae Tanaka

  26. Patterns of symptoms and insufficiency fractures in patients with tumour-induced osteomalacia

    Article • The Bone & Joint Journal, May 2023, Bone & Joint

    Dr. Sakae Tanaka

  27. Nutrient-regulated dynamics of chondroprogenitors in the postnatal murine growth plate

    Article • Bone Research, April 2023, Tsinghua University Press

    Dr. Sakae Tanaka

  28. Practical guidance to handle missing values in the 25-question Geriatric Locomotive Function Scale (GLFS-25): a simulation study

    Article • BMJ Open, December 2022, BMJ

    Dr. Sakae Tanaka

  29. Offset nail fixation for intertrochanteric fractures improves reduction and lag screw position

    Article • PLOS One, November 2022, PLOS

    Dr. Sakae Tanaka

  30. Interspecies Single‐Cell RNA‐Seq Analysis Reveals the Novel Trajectory of Osteoclast Differentiation and Therapeutic Targets

    Article • JBMR Plus, May 2022, Oxford University Press (OUP)

    Dr. Sakae Tanaka

  31. Transcription Factor Hematopoietically Expressed Homeobox Protein (Hhex) Negatively Regulates Osteoclast Differentiation by Controlling Cyclin‐Dependent Kinase Inhibitors

    Article • JBMR Plus, February 2022, Oxford University Press (OUP)

    Dr. Sakae Tanaka

  32. Relationship Between Age-Related Spinopelvic Sagittal Alignment and Low Back Pain in Adults of Population-Based Cohorts: The ROAD Study

    Article • Journal of Pain Research, January 2022, Taylor & Francis

    Dr. Sakae Tanaka

  33. Correction to: Systemic inflammatory responses after orthopedic surgery in patients with rheumatoid arthritis treated with tofacitinib

    Article • Clinical Rheumatology, November 2021, Springer Science + Business Media

    Dr. Sakae Tanaka

  34. Systemic inflammatory responses after orthopedic surgery in patients with rheumatoid arthritis treated with tofacitinib

    Article • Clinical Rheumatology, September 2021, Springer Science + Business Media

    Dr. Sakae Tanaka

  35. Parsing multiomics landscape of activated synovial fibroblasts highlights drug targets linked to genetic risk of rheumatoid arthritis

    Article • Annals of the Rheumatic Diseases, April 2021, Elsevier

    Dr. Sakae Tanaka

  36. Long-term safety and effectiveness of denosumab in Japanese patients with osteoporosis: 3-year post-marketing surveillance study

    Article • Journal of Bone and Mineral Metabolism, January 2021, Springer Science + Business Media

    Dr. Sakae Tanaka

  37. Treatment of acromioclavicular joint separations in Japan: a survey

    Article • JSES International, January 2021, Elsevier

    Dr. Sakae Tanaka

  38. Correction to: RANKL as a therapeutic target of rheumatoid arthritis

    Article • Journal of Bone and Mineral Metabolism, December 2020, Springer Science + Business Media

    Dr. Sakae Tanaka

  39. Sclerostin: from bench to bedside

    Article • Journal of Bone and Mineral Metabolism, November 2020, Springer Science + Business Media

    Dr. Sakae Tanaka

  40. RANKL as a therapeutic target of rheumatoid arthritis

    Article • Journal of Bone and Mineral Metabolism, October 2020, Springer Science + Business Media

    Dr. Sakae Tanaka

  41. Disease activity affects the recurrent deformities of the lesser toes after resection arthroplasty for rheumatoid forefoot deformity

    Article • Modern Rheumatology, June 2020, Taylor & Francis

    Dr. Sakae Tanaka

  42. Sustained anti-osteoporotic action of risedronate compared to anti-RANKL antibody following discontinuation in ovariectomized mice

    Article • Bone Reports, June 2020, Elsevier

    Dr. Sakae Tanaka

  43. Type 2 innate lymphoid cells inhibit the differentiation of osteoclasts and protect from ovariectomy-induced bone loss

    Article • Bone, March 2020, Elsevier

    Dr. Sakae Tanaka

  44. Relationship Between Pain Reduction and Improvement in Health-Related Quality of Life in Patients with Knee Pain Due to Osteoarthritis Receiving Duloxetine: Exploratory Post Hoc Analysis of a Japanese Phase 3 Randomized Study

    Article • Journal of Pain Research, January 2020, Taylor & Francis

    Dr. Sakae Tanaka

  45. 2‐Methacryloyloxyethyl Phosphorylcholine Polymer Coating Inhibits Bacterial Adhesion and Biofilm Formation on a Suture: An In Vitro and In Vivo Study

    Article • BioMed Research International, January 2020, Wiley

    Dr. Sakae Tanaka

  46. Surgical Treatment for Toe Deformities in Stiff-Person Syndrome

    Article • JBJS Essential Surgical Techniques, January 2020, Wolters Kluwer Health

    Dr. Sakae Tanaka

  47. Prevalence of Facet Effusion and Its Relationship with Lumbar Spondylolisthesis and Low Back Pain: The Wakayama Spine Study

    Article • Journal of Pain Research, December 2019, Taylor & Francis

    Dr. Sakae Tanaka

  48. Reconstruction Using Frozen Autograft for Disseminated Phosphaturic Mesenchymal Tumor of the Humerus after a Pathological Fracture

    Article • Case Reports in Orthopedics, September 2019, Hindawi Publishing Corporation

    Dr. Sakae Tanaka

  49. Mechanical regulation of bone homeostasis through p130Cas-mediated alleviation of NF-κB activity

    Article • Science Advances, September 2019, American Association for the Advancement of Science

    Dr. Sakae Tanaka

  50. Phase II/III, randomized, double-blind, parallel-group study of monthly delayed-release versus daily immediate-release risedronate tablets in Japanese patients with involutional osteoporosis

    Article • Journal of Bone and Mineral Metabolism, August 2019, Springer Science + Business Media

    Dr. Sakae Tanaka

  51. Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds

    Article • Stem Cell Reports, August 2019, Elsevier

    Dr. Sakae Tanaka

  52. Efficacy and safety of peficitinib (ASP015K) in patients with rheumatoid arthritis and an inadequate response to conventional DMARDs: a randomised, double-blind, placebo-controlled phase III trial (RAJ3)

    Article • Annals of the Rheumatic Diseases, July 2019, BMJ

    Dr. Sakae Tanaka

  53. Efficacy and safety of peficitinib (ASP015K) in patients with rheumatoid arthritis and an inadequate response to methotrexate: results of a phase III randomised, double-blind, placebo-controlled trial (RAJ4) in Japan

    Article • Annals of the Rheumatic Diseases, July 2019, BMJ

    Dr. Sakae Tanaka

  54. Factors related to the quality of life in patients with bone metastases

    Article • Clinical & Experimental Metastasis, July 2019, Springer Science + Business Media

    Dr. Sakae Tanaka

  55. Development of nomograms for prognostication of patients with primary soft tissue sarcomas of the trunk and extremity: report from the Bone and Soft Tissue Tumor Registry in Japan

    Article • BMC Cancer, July 2019, Springer Science + Business Media

    Dr. Sakae Tanaka

  56. A sliding scale to predict postoperative complications undergoing posterior spine surgery

    Article • Journal of Orthopaedic Science, July 2019, Elsevier

    Dr. Sakae Tanaka

  57. Hypermobile Medial Meniscus

    Article • JBJS Essential Surgical Techniques, July 2019, Wolters Kluwer Health

    Dr. Sakae Tanaka

  58. Factors affecting bone union after distal shortening oblique osteotomy of the lesser metatarsals

    Article • Modern Rheumatology, June 2019, Taylor & Francis

    Dr. Sakae Tanaka

  59. Lysophosphatidic acids and their substrate lysophospholipids in cerebrospinal fluid as objective biomarkers for evaluating the severity of lumbar spinal stenosis

    Article • Scientific Reports, June 2019, Springer Science + Business Media

    Dr. Sakae Tanaka

  60. Prevalence and co-existence of locomotive syndrome, sarcopenia, and frailty: the third survey of Research on Osteoarthritis/Osteoporosis Against Disability (ROAD) study

    Article • Journal of Bone and Mineral Metabolism, June 2019, Springer Science + Business Media

    Dr. Sakae Tanaka

  61. Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway

    Article • Cellular and Molecular Life Sciences, June 2019, Springer Science + Business Media

    Dr. Sakae Tanaka

  62. Spinal cord swelling in patients with cervical compression myelopathy

    Article • BMC Musculoskeletal Disorders, June 2019, Springer Science + Business Media

    Dr. Sakae Tanaka

  63. Gorham-Stout Syndrome of the Shoulder Girdle Successfully Controlled by Antiresorptive Agents

    Article • JBJS Essential Surgical Techniques, June 2019, Wolters Kluwer Health

    Dr. Sakae Tanaka

  64. Intraoperative Tibial Anteroposterior Axis Could Not Be Replicated After Tibial Osteotomy in Total Knee Arthroplasty

    Article • The Journal of Arthroplasty, June 2019, Elsevier

    Dr. Sakae Tanaka

  65. Massively parallel sequencing of tenosynovial giant cell tumors reveals novel CSF1 fusion transcripts and novel somatic CBL mutations

    Article • International Journal of Cancer, May 2019, Wiley

    Dr. Sakae Tanaka

  66. Runx1 contributes to articular cartilage maintenance by enhancement of cartilage matrix production and suppression of hypertrophic differentiation

    Article • Scientific Reports, May 2019, Springer Science + Business Media

    Dr. Sakae Tanaka

  67. CTLA4‐Ig directly inhibits osteoclastogenesis by interfering with intracellular calcium oscillations in bone marrow macrophages

    Article • Journal of Bone and Mineral Research, May 2019, Wiley

    Dr. Sakae Tanaka

  68. Complications of implant removal in ankle fractures

    Article • Journal of Orthopaedics, May 2019, Elsevier

    Dr. Sakae Tanaka

  69. Effects of the anti-RANKL antibody denosumab on joint structural damage in patients with rheumatoid arthritis treated with conventional synthetic disease-modifying antirheumatic drugs (DESIRABLE study): a randomised, double-blind, placebo-controlled ph...

    Article • Annals of the Rheumatic Diseases, April 2019, BMJ

    Dr. Sakae Tanaka

  70. RANKL is a therapeutic target of bone destruction in rheumatoid arthritis

    Article • F1000Research, April 2019, Faculty of 1000, Ltd.

    Dr. Sakae Tanaka

  71. Predictive factors for complications after surgical treatment for schwannomas of the extremities

    Article • BMC Musculoskeletal Disorders, April 2019, Springer Science + Business Media

    Dr. Sakae Tanaka

  72. Bicruciate-stabilised total knee arthroplasty provides good functional stability during high-flexion weight-bearing activities

    Article • Knee Surgery Sports Traumatology Arthroscopy, April 2019, Springer Science + Business Media

    Dr. Sakae Tanaka

  73. Molecular understanding of pharmacological treatment of osteoporosis

    Article • EFORT Open Reviews, April 2019, Bone & Joint

    Dr. Sakae Tanaka

  74. Influence of incidental dural tears and their primary microendoscopic repairs on surgical outcomes in patients undergoing microendoscopic lumbar surgery

    Article • The Spine Journal, April 2019, Elsevier

    Dr. Sakae Tanaka

  75. Minimal clinically important differences in Toronto Extremity Salvage Score for patients with lower extremity sarcoma

    Article • Journal of Orthopaedic Science, April 2019, Elsevier

    Dr. Sakae Tanaka

  76. Excessive mechanical loading promotes osteoarthritis through the gremlin-1–NF-κB pathway

    Article • Nature Communications, March 2019, Springer Science + Business Media

    Dr. Sakae Tanaka

  77. Minimum clinically important difference in outcome scores among patients undergoing cervical laminoplasty

    Article • European Spine Journal, March 2019, Springer Science + Business Media

    Dr. Sakae Tanaka

  78. Association Between Normothermia at the End of Surgery and Postoperative Complications Following Orthopedic Surgery

    Article • Clinical Infectious Diseases, March 2019, Oxford University Press (OUP)

    Dr. Sakae Tanaka

  79. Hypoglossal Nerve Palsy as a Cause of Severe Dysphagia along with the Oropharyngeal Stenosis due to Occipitocervical Kyphosis

    Article • Case Reports in Orthopedics, March 2019, Hindawi Publishing Corporation

    Yuki Taniguchi, Dr. Sakae Tanaka, Yoshitaka Matsubayashi

  80. Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin‐fixed paraffin‐embedded specimens

    Article • Cancer Science, March 2019, Wiley

    Dr. Sakae Tanaka

  81. Effects of a roughened femoral head and the locus of grafting on the wear resistance of the phospholipid polymer-grafted acetabular liner

    Article • Acta Biomaterialia, March 2019, Elsevier

    Dr. Sakae Tanaka

  82. Multi-layered PLLA-nanosheets loaded with FGF-2 induce robust bone regeneration with controlled release in critical-sized mouse femoral defects

    Article • Acta Biomaterialia, February 2019, Elsevier

    Dr. Sakae Tanaka

  83. Successful Treatment of Atlantoaxial Subluxation in an Adolescent Patient with BrachytelephalangicChondrodysplasia Punctata

    Article • Case Reports in Orthopedics, January 2019, Hindawi Publishing Corporation

    Yoshitaka Matsubayashi, Dr. Sakae Tanaka, Nobuhiko Haga, Yuki Taniguchi

  84. Bilateral Stress Fractures of the Talus Associated with Adult-Acquired Flatfoot Deformities

    Article • Case Reports in Orthopedics, September 2018, Hindawi Publishing Corporation

    Dr. Sakae Tanaka

  85. Mental State Can Influence the Degree of Postoperative Axial Neck Pain Following Cervical Laminoplasty

    Article • Global Spine Journal, August 2018, SAGE Publications

    Dr. Sakae Tanaka

  86. Validation study of a diagnostic scoring system for sacroiliac joint-related pain

    Article • Journal of Pain Research, August 2018, Dove Medical Press

    Dr. Sakae Tanaka

  87. Heterotopic Ossification of the Peroneus Longus Tendon in the Retromalleolar Portion with the Peroneus Quartus Muscle: A Case Report

    Article • Case Reports in Orthopedics, July 2018, Hindawi Publishing Corporation

    Dr. Sakae Tanaka

  88. Wrist Arthrodesis in Rheumatoid Arthritis Using an LCP Metaphyseal Locking Plate versus an AO Wrist Fusion Plate

    Article • International Journal of Rheumatology, July 2018, Hindawi Publishing Corporation

    Dr. Sakae Tanaka

  89. The utility of 25-question Geriatric Locomotive Function Scale for evaluating functional ability and disease activity in Japanese rheumatoid arthritis patients: A cross-sectional study using NinJa database

    Article • Modern Rheumatology, April 2018, Taylor & Francis

    Dr Jun Hirose, Dr. Sakae Tanaka

  90. The effect of switching from teriparatide to anti-RANKL antibody on cancellous and cortical bone in ovariectomized mice

    Article • Bone, February 2018, Elsevier

    Dr. Sakae Tanaka

  91. Secondary Chondrosarcoma Presenting with Symptoms Similar to Thoracic Outlet Syndrome

    Article • Case Reports in Orthopedics, January 2018, Hindawi Publishing Corporation

    Dr. Sakae Tanaka

  92. Total Hip Arthroplasty in a Patient with Oto-Spondylo-Megaepiphyseal Dysplasia Planned by Three-Dimensional Motion Analyses and Full-Scale Three-Dimensional Plaster Model of Bones

    Article • Case Reports in Orthopedics, January 2018, Hindawi Publishing Corporation

    Dr. Sakae Tanaka, Nobuhiko Haga

  93. RANKL: A therapeutic target for bone destruction in rheumatoid arthritis

    Article • Modern Rheumatology, September 2017, Taylor & Francis

    Dr. Sakae Tanaka, Yoshiya Tanaka

  94. Characteristics of functional impairment in patients with long-standing rheumatoid arthritis based on range of motion of joints: Baseline data from a multicenter prospective observational cohort study to evaluate the effectiveness of joint surgery in t...

    Article • Modern Rheumatology, July 2017, Taylor & Francis

    Nobuhiko Haga, Keiichiro Nishida, Dr. Sakae Tanaka

  95. Progression, incidence, and risk factors for intervertebral disc degeneration in a longitudinal population-based cohort: the Wakayama Spine Study

    Article • Osteoarthritis and Cartilage, July 2017, Elsevier

    Dr. Sakae Tanaka

  96. Association of Lumbar Spondylolisthesis With Low Back Pain and Symptomatic Lumbar Spinal Stenosis in a Population-based Cohort

    Article • Spine, June 2017, Wolters Kluwer Health

    Dr. Sakae Tanaka

  97. Capturing microscopic features of bone remodeling into a macroscopic model based on biological rationales of bone adaptation

    Article • Biomechanics and Modeling in Mechanobiology, May 2017, Springer Science + Business Media

    Dr. Sakae Tanaka

  98. Molecular mechanisms underlying osteoarthritis development: Notch and NF-κB

    Article • May 2017, Springer Science + Business Media

    Dr. Sakae Tanaka

  99. Wear resistance of poly(2‐methacryloyloxyethyl phosphorylcholine)‐grafted carbon fiber reinforced poly(ether ether ketone) liners against metal and ceramic femoral heads

    Article • Journal of Biomedical Materials Research Part B Applied Biomaterials, May 2017, Wiley

    Kazuhiko Ishihara, Dr. Sakae Tanaka

  100. C7 sagittal vertical axis is the determinant of the C5–C7 angle in cervical sagittal alignment

    Article • The Spine Journal, May 2017, Elsevier

    Dr. Sakae Tanaka

  101. Prognostic factors associated with the surgical indication for lumbar spinal stenosis patients less responsive to conservative treatments

    Article • Journal of Orthopaedic Science, May 2017, Elsevier

    Dr. Sakae Tanaka

  102. Negative feedback loop of bone resorption by NFATc1-dependent induction of Cadm1

    Article • PLOS One, April 2017, PLOS

    Dr. Sakae Tanaka

  103. The prevalence of tandem spinal stenosis and its characteristics in a population-based MRI study: The Wakayama Spine Study

    Article • European Spine Journal, April 2017, Springer Science + Business Media

    Dr. Sakae Tanaka

  104. Mortality and morbidity after spinal surgery in patients with Parkinson's disease: a retrospective matched-pair cohort study

    Article • The Spine Journal, April 2017, Elsevier

    Dr. Sakae Tanaka

  105. Serum levels of matrix metalloproteinase-3 and autoantibodies related to rheumatoid arthritis in the general Japanese population and their association with osteoporosis and osteoarthritis: the ROAD study

    Article • Journal of Bone and Mineral Metabolism, April 2017, Springer Science + Business Media

    Dr. Sakae Tanaka

  106. Different regulation of limb development by p63 transcript variants

    Article • PLOS One, March 2017, PLOS

    Dr. Sakae Tanaka

  107. The effects of presence of a backside screw hole on biotribological behavior of phospholipid polymer-grafted crosslinked polyethylene

    Article • Journal of Biomedical Materials Research Part B Applied Biomaterials, March 2017, Wiley

    Dr. Sakae Tanaka

  108. The Japanese version of the STarT Back Tool predicts 6-month clinical outcomes of low back pain

    Article • Journal of Orthopaedic Science, March 2017, Elsevier

    Dr. Sakae Tanaka

  109. The role of medial meniscus posterior root tear and proximal tibial morphology in the development of spontaneous osteonecrosis and osteoarthritis of the knee

    Article • The Knee, March 2017, Elsevier

    Dr. Sakae Tanaka

  110. Regulation of Chondrocyte Survival in Mouse Articular Cartilage by p63

    Article • Arthritis & Rheumatology, February 2017, Wiley

    Dr. Sakae Tanaka

  111. RANKL-Independent Osteoclastogenesis: A Long-Standing Controversy

    Article • Journal of Bone and Mineral Research, February 2017, Wiley

    Dr. Sakae Tanaka

  112. Estimated risk for chronic pain determined using the generic STarT Back 5-item screening tool

    Article • Journal of Pain Research, February 2017, Dove Medical Press

    Dr Takahiko Yoshimoto, Dr. Sakae Tanaka

  113. Epidemiology of the locomotive syndrome: The research on osteoarthritis/osteoporosis against disability study 2005–2015

    Article • Modern Rheumatology, January 2017, Taylor & Francis

    Dr. Sakae Tanaka

  114. Skeletal-related events and prognosis in urothelial cancer patients with bone metastasis

    Article • International Journal of Clinical Oncology, January 2017, Springer Science + Business Media

    Dr. Sakae Tanaka

  115. Multiple Acrometastases in a Patient with Renal Pelvic Urothelial Cancer

    Article • Case Reports in Urology, January 2017, Hindawi Publishing Corporation

    Dr. Sakae Tanaka, Nobuhiko Haga

  116. Recalcitrant Lateral Premalleolar Bursitis of the Ankle Associated with Lateral Ankle Instability

    Article • Case Reports in Orthopedics, January 2017, Hindawi Publishing Corporation

    Dr. Sakae Tanaka

  117. Anterior Impingement Syndrome of the Ankle Caused by Osteoid Osteoma in the Talar Neck Treated with Arthroscopy and 3D C-Arm-Based Imaging

    Article • Case Reports in Orthopedics, January 2017, Hindawi Publishing Corporation

    Dr. Sakae Tanaka

  118. A hydrated phospholipid polymer-grafted layer prevents lipid-related oxidative degradation of cross-linked polyethylene

    Article • Biomaterials, January 2017, Elsevier

    Dr. Sakae Tanaka

  119. Stenosing Tenosynovitis of the Flexor Hallucis Longus Tendon Associated with the Plantar Capsular Accessory Ossicle at the Interphalangeal Joint of the Great Toe

    Article • Case Reports in Orthopedics, January 2017, Hindawi Publishing Corporation

    Dr. Sakae Tanaka

  120. Real-world evidence of raloxifene versus alendronate in preventing non-vertebral fractures in Japanese women with osteoporosis: retrospective analysis of a hospital claims database

    Article • Journal of Bone and Mineral Metabolism, December 2016, Springer Science + Business Media

    Dr. Sakae Tanaka

  121. The relationship between findings on magnetic resonance imaging and previous history of low back pain

    Article • Journal of Pain Research, December 2016, Dove Medical Press

    Dr. Sakae Tanaka

  122. Patient Satisfaction with Posterior Decompression Surgery for Cervical Ossification of the Posterior Longitudinal Ligament: Prognostic Radiographic Factors and Patient-Reported Outcomes for the Effectiveness of Surgical Treatment

    Article • World Neurosurgery, December 2016, Elsevier

    Dr. Sakae Tanaka

  123. Treatment of spinal cord injury by an advanced cell transplantation technology using brain-derived neurotrophic factor-transfected mesenchymal stem cell spheroids

    Article • Biomaterials, December 2016, Elsevier

    Dr. Sakae Tanaka

  124. Is osteoporosis a predictor for future sarcopenia or vice versa? Four-year observations between the second and third ROAD study surveys

    Article • Osteoporosis International, November 2016, Springer Science + Business Media

    Dr. Sakae Tanaka

  125. Clinical safety and wear resistance of the phospholipid polymer-grafted highly cross-linked polyethylene liner

    Article • Journal of Orthopaedic Research®, November 2016, Wiley

    Dr. Sakae Tanaka

  126. Relationship between roentgenographic joint destruction in the hands and functional disorders among patients with rheumatoid arthritis

    Article • Modern Rheumatology, November 2016, Taylor & Francis

    Dr. Sakae Tanaka

  127. A Patient-Specific Instrument for Femoral Stem Placement During Total Hip Arthroplasty

    Article • Orthopedics, November 2016, SLACK, Inc.

    Dr. Sakae Tanaka

  128. Biphasic regulation of chondrocytes by Rela through induction of anti-apoptotic and catabolic target genes

    Article • Nature Communications, November 2016, Springer Science + Business Media

    Dr. Sakae Tanaka

  129. Diagnosing Discogenic Low Back Pain Associated with Degenerative Disc Disease Using a Medical Interview

    Article • PLOS One, November 2016, PLOS

    Dr. Sakae Tanaka

  130. Effect of Preoperative Sagittal Balance on Cervical Laminoplasty Outcomes

    Article • Spine, November 2016, Wolters Kluwer Health

    Dr. Sakae Tanaka

  131. Total Talar Replacement for Idiopathic Necrosis of the Talus: A Case Report

    Article • The Journal of Foot & Ankle Surgery, November 2016, Elsevier

    Dr. Sakae Tanaka

  132. Time trends and risk factors for perioperative complications in total ankle arthroplasty: retrospective analysis using a national database in Japan

    Article • BMC Musculoskeletal Disorders, October 2016, Springer Science + Business Media

    Dr. Sakae Tanaka

  133. The Serum Phosphorylated Neurofilament Heavy Subunit as a Predictive Marker for Outcome in Adult Patients after Traumatic Brain Injury

    Article • Journal of Neurotrauma, October 2016, Mary Ann Liebert Inc

    Dr. Sakae Tanaka

  134. Smad4 is required to inhibit osteoclastogenesis and maintain bone mass

    Article • Scientific Reports, October 2016, Springer Science + Business Media

    Dr. Sakae Tanaka

  135. Classification of High Intensity Zones of the Lumbar Spine and Their Association with Other Spinal MRI Phenotypes: The Wakayama Spine Study

    Article • PLOS One, September 2016, PLOS

    Dr. Sakae Tanaka

  136. The crucial role of Erk2 in demyelinating inflammation in the central nervous system

    Article • Journal of Neuroinflammation, September 2016, Springer Science + Business Media

    Dr Kazuhito Morioka, Dr. Sakae Tanaka

  137. Evaluation of wear suppression for phospholipid polymer-grafted ultra-high molecular weight polyethylene at concentrated contact

    Article • Tribology International, September 2016, Elsevier

    Dr. Sakae Tanaka

  138. Postoperative outcomes of major lower extremity amputations in patients with diabetes and peripheral artery disease: analysis using the Diagnosis Procedure Combination database in Japan

    Article • The American Journal of Surgery, September 2016, Elsevier

    Dr. Sakae Tanaka

  139. The Association between the Cross-Sectional Area of the Dural Sac and Low Back Pain in a Large Population: The Wakayama Spine Study

    Article • PLOS One, August 2016, PLOS

    Dr. Sakae Tanaka

  140. Dnmt3a Regulates Proliferation of Muscle Satellite Cells via p57Kip2

    Article • PLoS Genetics, July 2016, PLOS

    Dr. Sakae Tanaka

  141. A population approach to analyze the effectiveness of a back extension exercise “One Stretch” in patients with low back pain: A replication study

    Article • Journal of Orthopaedic Science, July 2016, Elsevier

    Dr. Sakae Tanaka

  142. Impingement of the Mobile Bearing on the Lateral Wall of the Tibial Tray in Unicompartmental Knee Arthroplasty

    Article • The Journal of Arthroplasty, July 2016, Elsevier

    Dr. Sakae Tanaka

  143. Identification of Nedd9 as a TGF-β-Smad2/3 Target Gene Involved in RANKL-Induced Osteoclastogenesis by Comprehensive Analysis

    Article • PLOS One, June 2016, PLOS

    Dr. Sakae Tanaka

  144. Myositis ossificans after navigated knee surgery: A report of two cases and literature review

    Article • The Knee, June 2016, Elsevier

    Dr. Sakae Tanaka

  145. A modified technique to reduce tibial keel cutting errors during an Oxford unicompartmental knee arthroplasty

    Article • Knee Surgery Sports Traumatology Arthroscopy, May 2016, Springer Science + Business Media

    Dr. Sakae Tanaka

  146. Thoracic intradural extramedullary lesions causing progressive myelopathy as an initial manifestation of granulomatosis with polyangiitis: a case report and review of literature

    Article • Journal of Spinal Cord Medicine, April 2016, Taylor & Francis

    Dr. Sakae Tanaka

  147. Cervical Anterolisthesis

    Article • Spine, April 2016, Wolters Kluwer Health

    Dr. Sakae Tanaka

  148. Comparison of mouse and human ankles and establishment of mouse ankle osteoarthritis models by surgically-induced instability

    Article • Osteoarthritis and Cartilage, April 2016, Elsevier

    Dr. Sakae Tanaka

  149. Prevalence of hand osteoarthritis and its relationship to hand pain and grip strength in Japan: The third survey of the ROAD study

    Article • Modern Rheumatology, February 2016, Taylor & Francis

    Dr. Sakae Tanaka

  150. Predictive Factors for Subjective Improvement in Lumbar Spinal Stenosis Patients with Nonsurgical Treatment: A 3-Year Prospective Cohort Study

    Article • PLOS One, February 2016, PLOS

    Dr. Sakae Tanaka

  151. Metabolic Syndrome Components Are Associated with Intervertebral Disc Degeneration: The Wakayama Spine Study

    Article • PLOS One, February 2016, PLOS

    Dr. Sakae Tanaka

  152. Does the microendoscopic technique reduce mortality and major complications in patients undergoing lumbar discectomy? A propensity score–matched analysis using a nationwide administrative database

    Article • Neurosurgical FOCUS, February 2016, Journal of Neurosurgery Publishing Group (JNSPG)

    Professor Hideo Yasunaga, Takeshi Oichi, Dr. Sakae Tanaka

  153. Foreword

    Article • January 2016, Elsevier

    Dr. Sakae Tanaka

  154. Extensive ossification of the paraspinal ligaments in a patient with vitamin D-resistant rickets: Case report with literature review

    Article • International Journal of Surgery Case Reports, January 2016, Elsevier

    Dr. Sakae Tanaka

  155. Interdigital Neuroma in the Second Intermetatarsal Space Associated with Metatarsophalangeal Joint Instability

    Article • Case Reports in Orthopedics, January 2016, Hindawi Publishing Corporation

    Dr. Sakae Tanaka

  156. Missed Medial Malleolar Fracture Associated With Achilles Tendon Rupture: A Case Report and Literature Review

    Article • The Journal of Foot & Ankle Surgery, January 2016, Elsevier

    Dr. Sakae Tanaka

  157. Prevalence of radiographic hip osteoarthritis and its association with hip pain in Japanese men and women: the ROAD study

    Article • Osteoarthritis and Cartilage, January 2016, Elsevier

    Dr. Sakae Tanaka

  158. Risk of infectious complications associated with blood transfusion in elective spinal surgery—a propensity score matched analysis

    Article • The Spine Journal, January 2016, Elsevier

    Dr. Sakae Tanaka

  159. Twice cutting method reduces tibial cutting error in unicompartmental knee arthroplasty

    Article • The Knee, January 2016, Elsevier

    Dr. Sakae Tanaka

  160. Concurrent spinal schwannoma and meningioma mimicking a single cervical dumbbell-shaped tumor: case report

    Article • Journal of Neurosurgery Spine, December 2015, Journal of Neurosurgery Publishing Group (JNSPG)

    Takeshi Oichi, Yoshitaka Matsubayashi, Dr. Sakae Tanaka, Yuki Taniguchi

  161. Evaluation of Comorbidity Indices for a Study of Patient Outcomes Following Cervical Decompression Surgery

    Article • Spine, December 2015, Wolters Kluwer Health

    Dr. Sakae Tanaka

  162. Hand-Held Bone Cutting Tool With Autonomous Penetration Detection for Spinal Surgery

    Article • IEEE/ASME Transactions on Mechatronics, December 2015, Institute of Electrical & Electronics Engineers (IEEE)

    Dr. Sakae Tanaka

  163. Psychometric Validation of the Japanese Version of the Neuropathic Pain Symptom Inventory

    Article • PLOS One, November 2015, PLOS

    Dr. Sakae Tanaka

  164. The impact of joint disease on the Modified Health Assessment Questionnaire scores in rheumatoid arthritis patients: A cross-sectional study using the National Database of Rheumatic Diseases by iR-net in Japan

    Article • Modern Rheumatology, November 2015, Taylor & Francis

    Dr. Sakae Tanaka

  165. The effect of cartilage degeneration on ultrasound speed in human articular cartilage

    Article • Modern Rheumatology, November 2015, Taylor & Francis

    Dr. Sakae Tanaka

  166. Quadriceps muscle strength, radiographic knee osteoarthritis and knee pain: the ROAD study

    Article • BMC Musculoskeletal Disorders, October 2015, Springer Science + Business Media

    Dr. Sakae Tanaka

  167. Complications and Postoperative Mortality Rate After Surgery for Pathological Femur Fracture Related to Bone Metastasis: Analysis of a Nationwide Database

    Article • Annals of Surgical Oncology, October 2015, Springer Science + Business Media

    Dr. Sakae Tanaka

  168. Perioperative stroke in patients undergoing elective spinal surgery: a retrospective analysis using the Japanese diagnosis procedure combination database

    Article • BMC Musculoskeletal Disorders, October 2015, Springer Science + Business Media

    Dr. Sakae Tanaka

  169. Phosphorylated neurofilament subunit levels in the serum of cervical compressive myelopathy patients

    Article • Journal of Clinical Neuroscience, October 2015, Elsevier

    Dr. Sakae Tanaka

  170. Association between dementia and postoperative complications after hip fracture surgery in the elderly: analysis of 87,654 patients using a national administrative database

    Article • Archives of Orthopaedic and Traumatic Surgery, September 2015, Springer Science + Business Media

    Dr. Sakae Tanaka

  171. Prevention of bacterial adhesion and biofilm formation on a vitamin E-blended, cross-linked polyethylene surface with a poly(2-methacryloyloxyethyl phosphorylcholine) layer

    Article • Acta Biomaterialia, September 2015, Elsevier

    Dr. Sakae Tanaka

  172. Quantitative and qualitative characterization of expanded CD4+ T cell clones in rheumatoid arthritis patients

    Article • Scientific Reports, August 2015, Springer Science + Business Media

    Dr. Sakae Tanaka

  173. Effects of extra irradiation on surface and bulk properties of PMPC-grafted cross-linked polyethylene

    Article • Journal of Biomedical Materials Research Part A, July 2015, Wiley

    Kazuhiko Ishihara, Dr. Sakae Tanaka

  174. Risk Factors for Prolonged Treatment of Whiplash-Associated Disorders

    Article • PLOS One, July 2015, PLOS

    Dr. Sakae Tanaka

  175. Elevated levels of phosphorylated neurofilament heavy subunit in the cerebrospinal fluid of patients with lumbar spinal stenosis: preliminary findings

    Article • The Spine Journal, July 2015, Elsevier

    Dr. Sakae Tanaka

  176. Repeated total en bloc spondylectomy for spinal metastases at different sites in one patient

    Article • European Spine Journal, July 2015, Springer Science + Business Media

    Dr. Sakae Tanaka

  177. Secure fixation of femoral bone plug with a suspensory button in anatomical anterior cruciate ligament reconstruction with bone-patellar tendon-bone graft

    Article • Joints, July 2015, Thieme Publishing Group

    Dr. Sakae Tanaka

  178. Disappearance of lung adenocarcinoma after total en bloc spondylectomy using frozen tumor-bearing vertebra for reconstruction

    Article • European Spine Journal, June 2015, Springer Science + Business Media

    Dr. Sakae Tanaka

  179. Factors affecting changes in the serum levels of 25-hydroxyvitamin D: a 3-year follow-up of the ROAD study

    Article • Osteoporosis International, June 2015, Springer Science + Business Media

    Dr. Sakae Tanaka

  180. Prediction of proximal femur strength by a quantitative computed tomography-based finite element method—Creation of predicted strength data of the proximal femur according to age range in a normal population

    Article • Modern Rheumatology, June 2015, Taylor & Francis

    Dr. Sakae Tanaka

  181. Prevalence of total knee arthroplasty and its predictive factors in Japanese patients with rheumatoid arthritis: Analysis using the NinJa cohort

    Article • Modern Rheumatology, June 2015, Taylor & Francis

    Dr. Sakae Tanaka

  182. 8-Iso-Prostaglandin F2α and Metabolic Syndrome

    Article • Obesity, June 2015, Wiley

    Dr Kanae Mure, Dr. Sakae Tanaka

  183. Influences of dehydration and rehydration on the lubrication properties of phospholipid polymer-grafted cross-linked polyethylene

    Article • Proceedings of the Institution of Mechanical Engineers Part H Journal of Engineering in Medicine, June 2015, SAGE Publications

    Dr. Sakae Tanaka

  184. Individual and combining effects of anti-RANKL monoclonal antibody and teriparatide in ovariectomized mice

    Article • Bone Reports, June 2015, Elsevier

    Dr. Sakae Tanaka

  185. Joint space narrowing, body mass index, and knee pain: the ROAD study (OAC1839R1)

    Article • Osteoarthritis and Cartilage, June 2015, Elsevier

    Dr. Sakae Tanaka

  186. Genomewide Comprehensive Analysis Reveals Critical Cooperation Between Smad and c-Fos in RANKL-Induced Osteoclastogenesis

    Article • Journal of Bone and Mineral Research, April 2015, Wiley

    Dr. Sakae Tanaka

  187. Wear resistance of the biocompatible phospholipid polymer-grafted highly cross-linked polyethylene liner against larger femoral head

    Article • Journal of Orthopaedic Research®, April 2015, Wiley

    Dr. Sakae Tanaka

  188. Comparison of the Japanese Orthopaedic Association (JOA) Score and Modified JOA (mJOA) Score for the Assessment of Cervical Myelopathy: A Multicenter Observational Study

    Article • PLOS One, April 2015, PLOS

    Dr. Sakae Tanaka

  189. Risks of In-Hospital Death and Complications After Fusion Surgery in Patients with Atlantoaxial Subluxation: Analysis of 1090 Patients Using the Japanese Diagnosis Procedure Combination Database

    Article • World Neurosurgery, April 2015, Elsevier

    Dr. Sakae Tanaka

  190. The association of combination of disc degeneration, end plate signal change, and Schmorl node with low back pain in a large population study: the Wakayama Spine Study

    Article • The Spine Journal, April 2015, Elsevier

    Dr. Sakae Tanaka

  191. Transcription factor Hes1 modulates osteoarthritis development in cooperation with calcium/calmodulin-dependent protein kinase 2

    Article • Proceedings of the National Academy of Sciences, March 2015, Proceedings of the National Academy of Sciences

    Dr. Sakae Tanaka

  192. Total Hip Arthroplasty After Rotational Acetabular Osteotomy

    Article • The Journal of Arthroplasty, March 2015, Elsevier

    Dr. Sakae Tanaka

  193. Prophylactic effect of fondaparinux and enoxaparin for preventing pulmonary embolism after total hip or knee arthroplasty: A retrospective observational study using the Japanese Diagnosis Procedure Combination database

    Article • Modern Rheumatology, February 2015, Taylor & Francis

    Dr. Sakae Tanaka

  194. Association between new indices in the locomotive syndrome risk test and decline in mobility: third survey of the ROAD study

    Article • Journal of Orthopaedic Science, January 2015, Elsevier

    Dr. Sakae Tanaka

  195. Effects of Surface Modification and Bulk Geometry on the Biotribological Behavior of Cross-Linked Polyethylene: Wear Testing and Finite Element Analysis

    Article • BioMed Research International, January 2015, Hindawi Publishing Corporation

    Dr. Sakae Tanaka

  196. Erratum to: Association between new indices in the locomotive syndrome risk test and decline in mobility: third survey of the ROAD study

    Article • Journal of Orthopaedic Science, January 2015, Elsevier

    Dr. Sakae Tanaka

  197. Intrathecal injection of a therapeutic gene-containing polyplex to treat spinal cord injury

    Article • Journal of Controlled Release, January 2015, Elsevier

    Dr. Sakae Tanaka

  198. Long-Term Outcomes of Cervical Laminoplasty in the Elderly

    Article • BioMed Research International, January 2015, Hindawi Publishing Corporation

    Dr. Sakae Tanaka

  199. Patient satisfaction with double-door laminoplasty for cervical compression myelopathy

    Article • Journal of Orthopaedic Science, January 2015, Elsevier

    Dr. Sakae Tanaka

  200. Prospective multicenter surveillance and risk factor analysis of deep surgical site infection after posterior thoracic and/or lumbar spinal surgery in adults

    Article • Journal of Orthopaedic Science, January 2015, Elsevier

    Dr. Sakae Tanaka

  201. Regulation of mouse chondrocyte differentiation by CCAAT/enhancer-binding proteins

    Article • Biomedical Research, January 2015, Biomedical Research Press

    Dr. Sakae Tanaka

  202. Temporal Trends in Characteristics of Newly Diagnosed Nontraumatic Osteonecrosis of the Femoral Head From 1997 to 2011: A Hospital-Based Sentinel Monitoring System in Japan

    Article • Journal of Epidemiology, January 2015, Japan Epidemiological Association

    Dr. Sakae Tanaka

  203. Identification of SCAN Domain Zinc-Finger Gene ZNF449 as a Novel Factor of Chondrogenesis

    Article • PLOS One, December 2014, PLOS

    Dr. Sakae Tanaka

  204. SOX10 Transactivates S100B to Suppress Schwann Cell Proliferation and to Promote Myelination

    Article • PLOS One, December 2014, PLOS

    Dr. Sakae Tanaka

  205. New simulation model for bone formation markers in osteoporosis patients treated with once-weekly teriparatide

    Article • Bone Research, December 2014, Springer Science + Business Media

    Dr. Sakae Tanaka

  206. Global epigenomic analysis indicates protocadherin-7 activates osteoclastogenesis by promoting cell–cell fusion

    Article • Biochemical and Biophysical Research Communications, December 2014, Elsevier

    Dr. Sakae Tanaka

  207. Mutual associations among musculoskeletal diseases and metabolic syndrome components: A 3-year follow-up of the ROAD study

    Article • Modern Rheumatology, November 2014, Taylor & Francis

    Dr. Sakae Tanaka

  208. Necrotising soft-tissue infections of the upper limb: risk factors for amputation and death

    Article • The Bone & Joint Journal, November 2014, Bone & Joint

    Dr. Sakae Tanaka

  209. Effects of fondaparinux on pulmonary embolism following hemiarthroplasty for femoral neck fracture: a retrospective observational study using the Japanese Diagnosis Procedure Combination database

    Article • Journal of Orthopaedic Science, November 2014, Elsevier

    Professor Hideo Yasunaga, Dr. Sakae Tanaka

  210. Progression of ossification of the posterior longitudinal ligament of the thoracic spine following posterior decompression and stabilization

    Article • Journal of Neurosurgery Spine, November 2014, Journal of Neurosurgery Publishing Group (JNSPG)

    Dr. Sakae Tanaka

  211. Multidirectional Wear and Impact-to-wear Tests of Phospholipid-polymer-grafted and Vitamin E-blended Crosslinked Polyethylene: A Pilot Study

    Article • Clinical Orthopaedics and Related Research, October 2014, Wolters Kluwer Health

    Dr. Sakae Tanaka

  212. Ischemic stroke after cervical spine injury: analysis of 11,005 patients using the Japanese Diagnosis Procedure Combination database

    Article • The Spine Journal, October 2014, Elsevier

    Dr. Sakae Tanaka

  213. Serum levels of 25-hydroxyvitamin D and the occurrence of musculoskeletal diseases: a 3-year follow-up to the road study

    Article • Osteoporosis International, August 2014, Springer Science + Business Media

    Dr. Sakae Tanaka

  214. Clinical and radiographic outcomes of total hip replacement with poly(2-methacryloyloxyethyl phosphorylcholine)-grafted highly cross-linked polyethylene liners: Three-year results of a prospective consecutive series

    Article • Modern Rheumatology, August 2014, Taylor & Francis

    Dr. Sakae Tanaka

  215. Development of femoral bone fracture model simulating muscular contraction force by pneumatic rubber actuator

    Article • August 2014, Institute of Electrical & Electronics Engineers (IEEE)

    Dr. Sakae Tanaka

  216. Poly(2-methacryloyloxyethyl phosphorylcholine) grafting and vitamin E blending for high wear resistance and oxidative stability of orthopedic bearings

    Article • Biomaterials, August 2014, Elsevier

    Dr. Sakae Tanaka

  217. Lipopolysaccharide preconditioning facilitates M2 activation of resident microglia after spinal cord injury

    Article • Journal of Neuroscience Research, July 2014, Wiley

    Dr Kazuhito Morioka, Dr. Sakae Tanaka

  218. Clinical Trials Express:Fracture Risk Reduction With Denosumab in Japanese Postmenopausal Women and Men With Osteoporosis: Denosumab Fracture Intervention Randomized Placebo Controlled Trial (DIRECT)

    Article • The Journal of Clinical Endocrinology & Metabolism, July 2014, Endocrine Society

    Dr. Sakae Tanaka

  219. Clinical characteristics of rheumatoid arthritis patients undergoing cervical spine surgery: an analysis of National Database of Rheumatic Diseases in Japan

    Article • BMC Musculoskeletal Disorders, June 2014, Springer Science + Business Media

    Dr. Sakae Tanaka

  220. Eccentric Femoral Tunnel Widening in Anatomic Anterior Cruciate Ligament Reconstruction

    Article • Arthroscopy The Journal of Arthroscopic and Related Surgery, June 2014, Elsevier

    Dr. Sakae Tanaka

  221. Does osteophytosis at the knee predict health-related quality of life decline? A 3-year follow-up of the ROAD study

    Article • Clinical Rheumatology, May 2014, Springer Science + Business Media

    Dr. Sakae Tanaka

  222. Cervical Microendoscopic Interlaminar Decompression through a Midline Approach in Patients with Cervical Myelopathy: A Technical Note

    Article • Journal of Neurological Surgery Part A Central European Neurosurgery, May 2014, Thieme Publishing Group

    Dr. Sakae Tanaka

  223. Nomogram Predicting Severe Adverse Events After Musculoskeletal Tumor Surgery: Analysis of a National Administrative Database

    Article • Annals of Surgical Oncology, May 2014, Springer Science + Business Media

    Professor Hideo Yasunaga, Dr. Sakae Tanaka

  224. Association of physical activities of daily living with the incidence of certified need of care in the long-term care insurance system of Japan: the ROAD study

    Article • Journal of Orthopaedic Science, May 2014, Elsevier

    Dr. Sakae Tanaka

  225. Autonomous penetration detection for bone cutting tool using demonstration-based learning

    Article • May 2014, Institute of Electrical & Electronics Engineers (IEEE)

    Dr. Sakae Tanaka

  226. A review of denosumab for the treatment of osteoporosis

    Article • Patient Preference and Adherence, April 2014, Taylor & Francis

    Dr. Sakae Tanaka

  227. Prevalence of diffuse idiopathic skeletal hyperostosis (DISH) of the whole spine and its association with lumbar spondylosis and knee osteoarthritis: the ROAD study

    Article • Journal of Bone and Mineral Metabolism, March 2014, Springer Science + Business Media

    Dr. Sakae Tanaka

  228. Association of knee osteoarthritis with onset and resolution of pain and physical functional disability: The ROAD study

    Article • Modern Rheumatology, March 2014, Taylor & Francis

    Dr. Sakae Tanaka

  229. Association of dietary intake with joint space narrowing and osteophytosis at the knee in Japanese men and women: the ROAD study

    Article • Modern Rheumatology, March 2014, Taylor & Francis

    Dr. Sakae Tanaka

  230. Grafting of poly(2-methacryloyloxyethyl phosphorylcholine) on polyethylene liner in artificial hip joints reduces production of wear particles

    Article • Journal of the Mechanical Behavior of Biomedical Materials, March 2014, Elsevier

    Dr. Sakae Tanaka

  231. Recurrent hemarthrosis after total knee arthroplasty caused by the impingement of a remnant lateral meniscus: A case report

    Article • The Knee, March 2014, Elsevier

    Dr. Sakae Tanaka

  232. Usefulness of QuickDASH in patients with cervical laminoplasty

    Article • Journal of Orthopaedic Science, March 2014, Elsevier

    Dr. Sakae Tanaka

  233. Anti-apoptotic Bcl-2 family member Mcl-1 regulates cell viability and bone-resorbing activity of osteoclasts

    Article • Bone, January 2014, Elsevier

    Dr. Sakae Tanaka

  234. Determination of differential gene expression profiles in superficial and deeper zones of mature rat articular cartilage using RNA sequencing of laser microdissected tissue specimens

    Article • Biomedical Research, January 2014, Biomedical Research Press

    Dr. Sakae Tanaka

  235. Midterm Results of Resection Arthroplasty for Forefoot Deformities in Patients with Rheumatoid Arthritis and the Risk Factors Associated with Patient Dissatisfaction

    Article • The Journal of Foot & Ankle Surgery, January 2014, Elsevier

    Dr. Sakae Tanaka

  236. S100A1 and S100B are dispensable for endochondral ossification during skeletal development

    Article • Biomedical Research, January 2014, Biomedical Research Press

    Dr. Sakae Tanaka

  237. Bone resorption is regulated by cell-autonomous negative feedback loop of Stat5–Dusp axis in the osteoclast

    Article • Journal of Experimental Medicine, December 2013, Rockefeller University Press

    Dr. Sakae Tanaka

  238. Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

    Article • Nature Reports Stem Cells, December 2013, Springer Science + Business Media

    Dr. Sakae Tanaka

  239. Vertebral fractures affect functional status in postmenopausal rheumatoid arthritis patients

    Article • Journal of Bone and Mineral Metabolism, December 2013, Springer Science + Business Media

    Dr. Sakae Tanaka

  240. Prevalence, incidence and progression of lumbar spondylosis by gender and age strata

    Article • Modern Rheumatology, November 2013, Taylor & Francis

    Dr. Sakae Tanaka

  241. Exercise habits during middle age are associated with lower prevalence of sarcopenia: the ROAD study

    Article • Osteoporosis International, October 2013, Springer Science + Business Media

    Dr. Sakae Tanaka

  242. Clinical outcome of anatomic double-bundle ACL reconstruction and 3D CT model-based validation of femoral socket aperture position

    Article • Knee Surgery Sports Traumatology Arthroscopy, October 2013, Springer Science + Business Media

    Dr. Sakae Tanaka

  243. Validity and Reliability of the Japanese Version of the painDETECT Questionnaire: A Multicenter Observational Study

    Article • PLOS One, September 2013, PLOS

    Dr. Sakae Tanaka

  244. Generation of Col2a1-EGFP iPS Cells for Monitoring Chondrogenic Differentiation

    Article • PLOS One, September 2013, PLOS

    Dr. Sakae Tanaka

  245. Incidence of certified need of care in the long-term care insurance system and its risk factors in the elderly of Japanese population-based cohorts: The ROAD study

    Article • Geriatrics and Gerontology International, September 2013, Wiley

    Dr. Sakae Tanaka

  246. Impact of Hospital Volume on Postoperative Complications and In-Hospital Mortality After Musculoskeletal Tumor Surgery

    Article • Journal of Bone and Joint Surgery, September 2013, The Journal of Bone and Joint Surgery, Inc.

    Professor Hideo Yasunaga, Dr. Sakae Tanaka

  247. Prevalence and progression of radiographic ossification of the posterior longitudinal ligament and associated factors in the Japanese population: a 3-year follow-up of the ROAD study

    Article • Osteoporosis International, August 2013, Springer Science + Business Media

    Dr. Sakae Tanaka

  248. Iliotibial band irritation caused by the EndoButton after anatomic double-bundle anterior cruciate ligament reconstruction: Report of two cases

    Article • The Knee, August 2013, Elsevier

    Dr. Sakae Tanaka

  249. Cervical canal stenosis caused by progressive fusion and enlargement of cervical vertebrae with features of Proteus syndrome and Klippel–Feil syndrome

    Article • Skeletal Radiology, June 2013, Springer Science + Business Media

    Dr. Sakae Tanaka

  250. Impact of age and comorbidity burden on mortality and major complications in older adults undergoing orthopaedic surgery: an analysis using the Japanese diagnosis procedure combination database

    Article • BMC Musculoskeletal Disorders, May 2013, Springer Science + Business Media

    Professor Hideo Yasunaga, Dr. Sakae Tanaka

  251. Profiles of vitamin D insufficiency and deficiency in Japanese men and women: association with biological, environmental, and nutritional factors and coexisting disorders: the ROAD study

    Article • Osteoporosis International, May 2013, Springer Science + Business Media

    Dr. Sakae Tanaka

  252. Influence of navigation system updates on total knee arthroplasty

    Article • Sports Medicine Arthroscopy Rehabilitation Therapy & Technology, May 2013, Springer Science + Business Media

    Dr. Sakae Tanaka

  253. An Additional Reference Axis Improves Femoral Rotation Alignment in Image-Free Computer Navigation Assisted Total Knee Arthroplasty

    Article • The Journal of Arthroplasty, May 2013, Elsevier

    Dr. Sakae Tanaka

  254. Economic Impact of Venous Thromboembolism Following Major Orthopaedic Surgery in Japan

    Article • Value in Health Regional Issues, May 2013, Elsevier

    Dr. Sakae Tanaka

  255. Regulation of bone resorption and sealing zone formation in osteoclasts occurs through protein kinase b-mediated microtubule stabilization

    Article • Journal of Bone and Mineral Research, April 2013, Wiley

    Dr. Sakae Tanaka

  256. Association of dietary intake with joint space narrowing and osteophytosis at the knee in Japanese men and women: the ROAD study

    Article • Modern Rheumatology, March 2013, Taylor & Francis

    Dr. Sakae Tanaka

  257. Mortality and morbidity after high-dose methylprednisolone treatment in patients with acute cervical spinal cord injury: a propensity-matched analysis using a nationwide administrative database

    Article • Emergency Medicine Journal, February 2013, BMJ

    Dr. Sakae Tanaka

  258. Associations between neck and shoulder discomfort (Katakori) and job demand, job control, and worksite support

    Article • Modern Rheumatology, January 2013, Taylor & Francis

    Dr. Sakae Tanaka

  259. Patellar Fracture After Total Knee Arthroplasty for Rheumatoid Arthritis

    Article • The Journal of Arthroplasty, January 2013, Elsevier

    Dr. Sakae Tanaka

  260. Pyogenic discitis due to Abiotrophia adiacens

    Article • International Journal of Surgery Case Reports, January 2013, Elsevier

    Dr. Sakae Tanaka

  261. Regulation of bone destruction in rheumatoid arthritis through RANKL-RANK pathways

    Article • World Journal of Orthopedics, January 2013, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Dr. Sakae Tanaka

  262. Risk factors for falls in a longitudinal population-based cohort study of Japanese men and women: The ROAD Study

    Article • Bone, January 2013, Elsevier

    Dr. Sakae Tanaka

  263. Ultrasonographic Evaluation of Displaced Neurovascular Bundle in Dupuytren Disease

    Article • The Journal Of Hand Surgery, January 2013, Elsevier

    Dr. Sakae Tanaka

  264. Class IA phosphatidylinositol 3-kinase regulates osteoclastic bone resorption through protein kinase B-mediated vesicle transport

    Article • Journal of Bone and Mineral Research, November 2012, Wiley

    Dr. Sakae Tanaka

  265. Regulation of RANKL-Induced Osteoclastogenesis by TGF-β

    Article • November 2012, Springer Science + Business Media

    Dr. Sakae Tanaka

  266. Accumulation of metabolic risk factors such as overweight, hypertension, dyslipidaemia, and impaired glucose tolerance raises the risk of occurrence and progression of knee osteoarthritis: a 3-year follow-up of the ROAD study

    Article • Osteoarthritis and Cartilage, November 2012, Elsevier

    Dr. Sakae Tanaka

  267. Natural Course and Prognostic Factors in Patients With Mild Cervical Spondylotic Myelopathy With Increased Signal Intensity on T2-Weighted Magnetic Resonance Imaging

    Article • Spine, October 2012, Wolters Kluwer Health

    Dr. Sakae Tanaka

  268. Intracellular and Extracellular ATP Coordinately Regulate the Inverse Correlation between Osteoclast Survival and Bone Resorption

    Article • Journal of Biological Chemistry, September 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Sakae Tanaka

  269. Three-Dimensional Fluoroscopic Navigation Guidance for Femoral Tunnel Creation in Revision Anterior Cruciate Ligament Reconstruction

    Article • Arthroscopy Techniques, September 2012, Elsevier

    Dr. Sakae Tanaka

  270. The mid-term efficacy of intra-articular hyaluronic acid injections on joint structure: a nested case control study

    Article • Modern Rheumatology, August 2012, Taylor & Francis

    Dr. Sakae Tanaka

  271. Recent Advance in Epigenetics - Application to The Regulation of Osteoclast Differentiation

    Article • Current Rheumatology Reviews, July 2012, Bentham Science Publishers

    Dr. Sakae Tanaka

  272. Analysis of the affected joints in rheumatoid arthritis patients in a large Japanese cohort

    Article • Modern Rheumatology, March 2012, Taylor & Francis

    Dr. Sakae Tanaka

  273. Fungal arthritis of the wrist caused by Candida parapsilosis during infliximab therapy for rheumatoid arthritis

    Article • Modern Rheumatology, February 2012, Taylor & Francis

    Dr. Sakae Tanaka

  274. Does mild cognitive impairment affect the occurrence of radiographic knee osteoarthritis? A 3-year follow-up in the ROAD study

    Article • BMJ Open, January 2012, BMJ

    Dr. Sakae Tanaka

  275. Risk factors affecting inhospital mortality after hip fracture: retrospective analysis using the Japanese Diagnosis Procedure Combination Database

    Article • BMJ Open, January 2012, BMJ

    Dr. Sakae Tanaka

  276. Risk Factors for Pulmonary Embolism and the Effects of Fondaparinux After Total Hip and Knee Arthroplasty: A Retrospective Observational Study with Use of a National Database in Japan

    Article • Journal of Bone and Joint Surgery, December 2011, The Journal of Bone and Joint Surgery, Inc.

    Professor Hideo Yasunaga, Dr. Sakae Tanaka

  277. Epigenetic regulation of osteoclast differentiation

    Article • Annals of the New York Academy of Sciences, December 2011, Wiley

    Dr. Sakae Tanaka

  278. Distinguishing the proapoptotic and antiresorptive functions of risedronate in murine osteoclasts: Role of the Akt pathway and the ERK/Bim axis

    Article • Arthritis & Rheumatism, November 2011, Wiley

    Dr. Sakae Tanaka

  279. Epigenetic regulation of osteoclast differentiation: Possible involvement of Jmjd3 in the histone demethylation of Nfatc1

    Article • Journal of Bone and Mineral Research, October 2011, Wiley

    Dr. Sakae Tanaka

  280. Are Bone and Serum Cefazolin Concentrations Adequate for Antimicrobial Prophylaxis?

    Article • Clinical Orthopaedics and Related Research, October 2011, Wolters Kluwer Health

    Dr. Sakae Tanaka

  281. Increased Bone Mass in Mice after Single Injection of Anti-receptor Activator of Nuclear Factor-κB Ligand-neutralizing Antibody

    Article • Journal of Biological Chemistry, August 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Sakae Tanaka

  282. Regulation of RANKL-induced osteoclastogenesis by TGF-β through molecular interaction between Smad3 and Traf6

    Article • Journal of Bone and Mineral Research, June 2011, Wiley

    Dr. Sakae Tanaka

  283. Bim: Guardian of Tissue Homeostasis and Critical Regulator of the Immune System, Tumorigenesis and Bone Biology

    Article • Archivum Immunologiae et Therapiae Experimentalis, June 2011, Springer Science + Business Media

    Dr. Sakae Tanaka

  284. Hes1 functions downstream of growth factors to maintain oligodendrocyte lineage cells in the early progenitor stage

    Article • Neuroscience, March 2011, Elsevier

    Dr Kazuhito Morioka, Dr. Sakae Tanaka

  285. Recent trends in orthopedic surgery performed in Japan for rheumatoid arthritis

    Article • Modern Rheumatology, February 2011, Taylor & Francis

    Dr. Sakae Tanaka

  286. tPA Activates LDL Receptor-Related Protein 1-Mediated Mitogenic Signaling Involving the p90RSK and GSK3β Pathway

    Article • American Journal Of Pathology, October 2010, Elsevier

    Dr. Sakae Tanaka

  287. Intra-articular injection of hyaluronan restores the aberrant expression of matrix metalloproteinase-13 in osteoarthritic subchondral bone

    Article • Journal of Orthopaedic Research®, September 2010, Wiley

    Dr. Sakae Tanaka

  288. Hyperphosphorylated neurofilament NF-H as a biomarker of the efficacy of minocycline therapy for spinal cord injury

    Article • Spinal Cord, August 2010, Springer Science + Business Media

    Dr. Sakae Tanaka

  289. The usefulness of neutrophil CD64 expression in the diagnosis of local infection in patients with rheumatoid arthritis in daily practice

    Article • Journal of Orthopaedic Science, July 2010, Elsevier

    Dr. Sakae Tanaka

  290. Neutrophil CD64 expression as a diagnostic marker for local infection and crystal-induced arthritis

    Article • Modern Rheumatology, June 2010, Taylor & Francis

    Dr. Sakae Tanaka

  291. Antiapoptotic molecule Bcl-2 is essential for the anabolic activity of parathyroid hormone in bone

    Article • Annals of the New York Academy of Sciences, April 2010, Wiley

    Dr. Sakae Tanaka

  292. Statistics for orthopedic surgery 2006–2007: data from the Japanese Diagnosis Procedure Combination database

    Article • Journal of Orthopaedic Science, March 2010, Elsevier

    Professor Hideo Yasunaga, Dr. Sakae Tanaka

  293. Impact of biologics on the prevalence of orthopedic surgery in the National Database of Rheumatic Diseases in Japan

    Article • Modern Rheumatology, January 2010, Taylor & Francis

    Dr. Sakae Tanaka

  294. PEDF regulates osteoclasts via osteoprotegerin and RANKL

    Article • Biochemical and Biophysical Research Communications, January 2010, Elsevier

    Dr. Sakae Tanaka

  295. New resorption assay with mouse osteoclast-like multinucleated cells formed in vitro

    Article • Journal of Bone and Mineral Research, December 2009, Wiley

    Dr. Sakae Tanaka

  296. Preparation and characterization of a mouse osteoclast-like multinucleated cell population

    Article • Journal of Bone and Mineral Research, December 2009, Wiley

    Dr. Sakae Tanaka

  297. NF-κB2 (p100) emerges as a negative regulator of TNFα-induced osteoclastogenesis

    Article • IBMS BoneKEy, December 2009, Portico

    Dr. Sakae Tanaka

  298. Anti-apoptotic Molecule Bcl-2 Regulates the Differentiation, Activation, and Survival of Both Osteoblasts and Osteoclasts

    Article • Journal of Biological Chemistry, October 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Sakae Tanaka

  299. NF-κB2 (p100) limits TNF-α–induced osteoclastogenesis

    Article • Journal of Clinical Investigation, October 2009, American Society for Clinical Investigation

    Dr. Sakae Tanaka

  300. The antiapoptotic protein Bcl-xL negatively regulates the bone-resorbing activity of osteoclasts in mice

    Article • Journal of Clinical Investigation, September 2009, American Society for Clinical Investigation

    Dr. Sakae Tanaka

  301. Over-expression of integrin β3 can partially overcome the defect of integrin β3 signaling in transglutaminase 2 null macrophages

    Article • Immunology Letters, September 2009, Elsevier

    Dr. Sakae Tanaka

  302. Neutrophil CD64 expression in the diagnosis of local musculoskeletal infection and the impact of antibiotics

    Article • Journal of Bone and Joint Surgery - British Volume, August 2009, Bone & Joint

    Dr. Sakae Tanaka

  303. Rheumatoid arthritis associated with osteopetrosis

    Article • Modern Rheumatology, August 2009, Taylor & Francis

    Dr. Sakae Tanaka

  304. Involvement of a disintegrin and metalloproteinase 10 and 17 in shedding of tumor necrosis factor-α

    Article • Biochemistry and Cell Biology, August 2009, Canadian Science Publishing

    Dr. Sakae Tanaka

  305. Prevalence of joint replacement surgery in rheumatoid arthritis patients: cross-sectional analysis in a large observational cohort in Japan

    Article • Modern Rheumatology, March 2009, Taylor & Francis

    Dr. Sakae Tanaka

  306. Regulation of Osteoclast Apoptosis by Bcl-2 Family Protein Bim and Caspase-3

    Article • January 2009, Springer Science + Business Media

    Dr. Sakae Tanaka

  307. Potential involvement of p53 in ischemia/reperfusion-induced osteonecrosis

    Article • Journal of Bone and Mineral Metabolism, November 2008, Springer Science + Business Media

    Dr. Sakae Tanaka

  308. A Novel Function of RING Finger Protein 10 in Transcriptional Regulation of the Myelin-Associated Glycoprotein Gene and Myelin Formation in Schwann Cells

    Article • PLOS One, October 2008, PLOS

    Dr. Sakae Tanaka

  309. Brain-type creatine kinase has a crucial role in osteoclast-mediated bone resorption

    Article • Nature Reports Stem Cells, August 2008, Springer Science + Business Media

    Dr. Sakae Tanaka

  310. Pivotal Role of Bcl-2 Family Proteins in the Regulation of Chondrocyte Apoptosis

    Article • Journal of Biological Chemistry, July 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Sakae Tanaka

  311. Tumor necrosis factor-α inhibits chondrogenic differentiation of synovial fibroblasts through p38 mitogen activating protein kinase pathways

    Article • Modern Rheumatology, April 2008, Taylor & Francis

    Dr. Sakae Tanaka

  312. Osteoporotic bone formation in mice lackingtob2; involvement of Tob2 in RANK ligand expression and osteoclasts differentiation

    Article • FEBS Letters, March 2008, Wiley

    Dr. Sakae Tanaka

  313. MKK6–p38 MAPK signaling pathway enhances survival but not bone-resorbing activity of osteoclasts

    Article • Biochemical and Biophysical Research Communications, January 2008, Elsevier

    Dr. Sakae Tanaka

  314. Posttranslational Regulation of Bim by Caspase-3

    Article • Annals of the New York Academy of Sciences, November 2007, Wiley

    Dr. Sakae Tanaka

  315. Akt1 in Osteoblasts and Osteoclasts Controls Bone Remodeling

    Article • PLOS One, October 2007, PLOS

    Dr. Sakae Tanaka

  316. Negative Feedback Loop in the Bim-Caspase-3 Axis Regulating Apoptosis and Activity of Osteoclasts

    Article • Journal of Bone and Mineral Research, June 2007, Wiley

    Dr. Sakae Tanaka

  317. Overexpression of γ-Glutamyltransferase in Transgenic Mice Accelerates Bone Resorption and Causes Osteoporosis

    Article • Endocrinology, June 2007, Endocrine Society

    Dr. Sakae Tanaka

  318. Scientific basis for the efficacy of combined use of antirheumatic drugs against bone destruction in rheumatoid arthritis

    Article • Modern Rheumatology, February 2007, Taylor & Francis

    Dr. Sakae Tanaka

  319. Molecular mechanism of bone destruction in rheumatoid arthritis

    Article • Future Rheumatology, February 2007, Future Medicine

    Dr. Sakae Tanaka

  320. Protein kinase C zeta plays an essential role for Mycobacterium tuberculosis-induced extracellular signal-regulated kinase 1/2 activation in monocytes/macrophages via Toll-like receptor 2

    Article • Cellular Microbiology, February 2007, Wiley

    Dr. Sakae Tanaka

  321. Ectodomain Shedding of Receptor Activator of NF-κB Ligand

    Article • January 2007, Springer Science + Business Media

    Dr. Sakae Tanaka

  322. Erk pathways negatively regulate matrix mineralization

    Article • Bone, January 2007, Elsevier

    Dr. Sakae Tanaka

  323. Signaling Axis in Osteoclast Biology and Therapeutic Targeting in the RANKL/RANK/OPG System

    Article • American Journal of Nephrology, January 2007, Karger Publishers

    Dr. Sakae Tanaka

  324. Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

    Article • Cell, December 2006, Elsevier

    Dr. Sakae Tanaka

  325. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction

    Article • Journal of Experimental Medicine, November 2006, Rockefeller University Press

    Dr. Sakae Tanaka

  326. Negative Regulation of Osteoclastogenesis by Ectodomain Shedding of Receptor Activator of NF-κB Ligand

    Article • Journal of Biological Chemistry, October 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Sakae Tanaka

  327. Pro-inflammatory Cytokine Tumor Necrosis Factor-α Induces Bone Morphogenetic Protein-2 in Chondrocytes via mRNA Stabilization and Transcriptional Up-regulation

    Article • Journal of Biological Chemistry, July 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Sakae Tanaka

  328. Molecular Mechanism of the Life and Death of the Osteoclast

    Article • Annals of the New York Academy of Sciences, April 2006, Wiley

    Dr. Sakae Tanaka

  329. The role of c-Src kinase in the regulation of osteoclast function

    Article • Modern Rheumatology, April 2006, Taylor & Francis

    Dr. Sakae Tanaka

  330. Tissue-type Plasminogen Activator Acts as a Cytokine That Triggers Intracellular Signal Transduction and Induces Matrix Metalloproteinase-9 Gene Expression

    Article • Journal of Biological Chemistry, November 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Sakae Tanaka

  331. Integrin α4β1 Promotes Focal Adhesion Kinase-Independent Cell Motility via α4 Cytoplasmic Domain-Specific Activation of c-Src

    Article • Molecular and Cellular Biology, November 2005, ASM Journals

    Dr. Sakae Tanaka

  332. Identification of an Alternatively Spliced Variant of Ca2+-promoted Ras Inactivator as a Possible Regulator of RANKL Shedding

    Article • Journal of Biological Chemistry, October 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Sakae Tanaka

  333. Regulation of Osteoclast Apoptosis and Motility by Small GTPase Binding Protein Rac1

    Article • Journal of Bone and Mineral Research, August 2005, Wiley

    Dr. Sakae Tanaka

  334. Monokine induced by interferon-  is induced by receptor activator of nuclear factor  B ligand and is involved in osteoclast adhesion and migration

    Article • Blood, April 2005, American Society of Hematology

    Dr. Sakae Tanaka

  335. Intracellular signal transduction pathways: good therapeutic targets for joint destruction in rheumatoid arthritis

    Article • Modern Rheumatology, February 2005, Taylor & Francis

    Dr. Sakae Tanaka

  336. RANK-mediated amplification of TRAF6 signaling leads to NFATc1 induction during osteoclastogenesis

    Article • The EMBO Journal, January 2005, Wiley

    Dr. Sakae Tanaka

  337. In vitro and in vivo assays for osteoclast apoptosis

    Article • Biological Procedures Online, January 2005, Springer Science + Business Media

    Dr. Sakae Tanaka

  338. Essential Role of Synoviolin in Embryogenesis

    Article • Journal of Biological Chemistry, December 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Sakae Tanaka

  339. Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation

    Article • Journal of Clinical Investigation, August 2004, American Society for Clinical Investigation

    Dr Fumiyo Ikeda, Dr. Sakae Tanaka

  340. Opposing Extracellular Signal-Regulated Kinase and Akt Pathways Control Schwann Cell Myelination

    Article • Journal of Neuroscience, July 2004, Society for Neuroscience

    Dr. Sakae Tanaka

  341. Osteoclast Differentiation by RANKL Requires NF-κB-Mediated Downregulation of Cyclin-Dependent Kinase 6 (Cdk6)

    Article • Journal of Bone and Mineral Research, May 2004, Wiley

    Dr. Sakae Tanaka

  342. Activation of ERK or inhibition of JNK ameliorates H2O2 cytotoxicity in mouse renal proximal tubule cells

    Article • Kidney International, April 2004, Elsevier

    Dr. Sakae Tanaka

  343. Distinct roles of Smad pathways and p38 pathways in cartilage-specific gene expression in synovial fibroblasts

    Article • Journal of Clinical Investigation, March 2004, American Society for Clinical Investigation

    Dr. Sakae Tanaka

  344. Fcγ receptor signaling in primary human microglia: differential roles of PI-3K and Ras/ERK MAPK pathways in phagocytosis and chemokine induction

    Article • Journal of Leukocyte Biology, February 2004, Wiley

    Dr. Sakae Tanaka

  345. Src Kinase Activity Is Essential for Osteoclast Function

    Article • Journal of Biological Chemistry, January 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Sakae Tanaka

  346. Suppression of T cell responses by chondromodulin I, a cartilage-derived angiogenesis inhibitory factor: Therapeutic potential in rheumatoid arthritis

    Article • Arthritis & Rheumatism, January 2004, Wiley

    Dr. Sakae Tanaka

  347. Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim

    Article • The EMBO Journal, December 2003, Wiley

    Dr. Sakae Tanaka

  348. Association of sustained ERK activity with integrin β3 induction during receptor activator of nuclear factor kappaB ligand (RANKL)-directed osteoclast differentiation

    Article • Experimental Cell Research, October 2003, Elsevier

    Dr. Sakae Tanaka

  349. Suppression of arthritic bone destruction by adenovirus-mediated dominant-negative Ras gene transfer to synoviocytes and osteoclasts

    Article • Arthritis & Rheumatism, September 2003, Wiley

    Dr. Sakae Tanaka

  350. Signal transduction pathways regulating osteoclast differentiation and function

    Article • Journal of Bone and Mineral Metabolism, May 2003, Springer Science + Business Media

    Dr. Sakae Tanaka

  351. Jun Dimerization Protein 2 (JDP2), a Member of the AP-1 Family of Transcription Factor, Mediates Osteoclast Differentiation Induced by RANKL

    Article • Journal of Experimental Medicine, April 2003, Rockefeller University Press

    Dr. Sakae Tanaka

  352. Extracellular Signal-regulated Kinase Mediates Phosphorylation of Tropomyosin-1 to Promote Cytoskeleton Remodeling in Response to Oxidative Stress: Impact on Membrane Blebbing

    Article • Molecular Biology of the Cell, April 2003, American Society for Cell Biology (ASCB)

    Dr. Sakae Tanaka

  353. Regulation of cytochromecoxidase activity by c-Src in osteoclasts

    Article • Journal of Cell Biology, March 2003, Rockefeller University Press

    Dr. Sakae Tanaka

  354. Traf6 is essential for murine tooth cusp morphogenesis

    Article • Developmental Dynamics, January 2003, Wiley

    Dr. Sakae Tanaka

  355. A novel therapeutic vaccine approach, targeting RANKL, prevents bone destruction in bone-related disorders

    Article • Journal of Bone and Mineral Metabolism, September 2002, Springer Science + Business Media

    Dr KAZUHIRO AOKI, Dr. Sakae Tanaka

  356. Usefulness of absorbable screws in the Sauvé-Kapandji procedure for rheumatoid wrist reconstruction

    Article • Modern Rheumatology, June 2002, Taylor & Francis

    Dr. Sakae Tanaka

  357. Macrophage Migration Inhibitory Factor Up-regulates Matrix Metalloproteinase-9 and -13 in Rat Osteoblasts

    Article • Journal of Biological Chemistry, December 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Sakae Tanaka

  358. Akt Protein Kinase Inhibits Non-apoptotic Programmed Cell Death Induced by Ceramide

    Article • Journal of Biological Chemistry, November 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Sakae Tanaka

  359. Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis

    Article • The EMBO Journal, March 2001, Wiley

    Dr. Sakae Tanaka

  360. Negative Regulation of BMP/Smad Signaling by Tob in Osteoblasts

    Article • Cell, December 2000, Elsevier

    Dr. Sakae Tanaka

  361. Partial Functional Recovery of Paraplegic Rat by Adenovirus-Mediated Gene Delivery of Constitutively Active MEK1

    Article • Experimental Neurology, November 2000, Elsevier

    Dr. Sakae Tanaka

  362. Reciprocal Role of ERK and Nf-κb Pathways in Survival and Activation of Osteoclasts

    Article • Journal of Cell Biology, January 2000, Rockefeller University Press

    Dr. Sakae Tanaka

  363. Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice

    Article • Genes to Cells, June 1999, Wiley

    Dr. Sakae Tanaka

  364. Giant trichoblastoma mimicking malignancy

    Article • Archives of Orthopaedic and Traumatic Surgery, May 1999, Springer Science + Business Media

    Dr. Sakae Tanaka

  365. Adenovirus-mediated Overexpression of C-terminal Src Kinase (Csk) in Type I Astrocytes Interferes with Cell Spreading and Attachment to Fibronectin

    Article • Journal of Biological Chemistry, January 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Sakae Tanaka

  366. Modulation of Osteoclast Function by Adenovirus Vector-Induced Epidermal Growth Factor Receptor

    Article • Journal of Bone and Mineral Research, November 1998, Wiley

    Dr. Sakae Tanaka

  367. A New Mechanism of Bone Destruction in Rheumatoid Arthritis: Synovial Fibroblasts Induce Osteoclastogenesis

    Article • Biochemical and Biophysical Research Communications, November 1997, Elsevier

    Dr. Sakae Tanaka

  368. Tiludronate inhibits protein tyrosine phosphatase activity in osteoclasts

    Article • Bone, May 1997, Elsevier

    Dr. Sakae Tanaka

  369. Bcl-2 Lies Downstream of Parathyroid Hormone–related Peptide in a Signaling Pathway That Regulates Chondrocyte Maturation during Skeletal Development

    Article • Journal of Cell Biology, January 1997, Rockefeller University Press

    Dr. Sakae Tanaka

  370. c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption

    Article • Nature, October 1996, Springer Science + Business Media

    Dr. Sakae Tanaka

  371. A possible mechanism of the specific action of bisphosphonates on osteoclasts: Tiludronate preferentially affects polarized osteoclasts having ruffled borders

    Article • Bone, August 1995, Elsevier

    Dr. Sakae Tanaka

  372. Possible involvement of focal adhesion kinase, p125FAK, in osteoclastic bone resorption

    Article • Journal of Cellular Biochemistry, August 1995, Wiley

    Dr. Sakae Tanaka

  373. Tyrosine Phosphorylation and Translocation of the c-Cbl Protein after Activation of Tyrosine Kinase Signaling Pathways

    Article • Journal of Biological Chemistry, June 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Sakae Tanaka

  374. Wortmannin, a specific inhibitor of phosphatidylinositol-3 kinase, blocks osteoclastic bone resorption

    Article • FEBS Letters, March 1995, Wiley

    Dr. Sakae Tanaka

  375. Postmitotic Osteoclast Precursors Are Mononuclear Cells Which Express Macrophage-Associated Phenotypes

    Article • Developmental Biology, May 1994, Elsevier

    Dr. Sakae Tanaka

  376. Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6.

    Article • Proceedings of the National Academy of Sciences, December 1993, Proceedings of the National Academy of Sciences

    Dr. Sakae Tanaka

  377. Macrophage colon-stimulating factor (M-CSF) is essential for differentiation rather than proliferation of osteoclast progenitors

    Article • Osteoporosis International, January 1993, Springer Science + Business Media

    Dr. Sakae Tanaka

  378. Osteoclasts express high levels of p60c-src , preferentially on ruffled border membranes

    Article • FEBS Letters, November 1992, Wiley

    Dr. Sakae Tanaka

  379. Lack of bone resorption in osteosclerotic (oc/oc) mice is due to a defect in osteoclast progenitors rather than the local microenvironment provided by osteoblastic cells

    Article • Biochemical and Biophysical Research Communications, April 1992, Elsevier

    Dr. Sakae Tanaka

  380. Generating Murine Osteoclasts from Bone Marrow

    Article • Springer Science + Business Media

    Dr. Sakae Tanaka