All Stories

  1. The anti-apoptotic ubiquitin conjugating enzyme BIRC6/BRUCE regulates autophagosome-lysosome fusion

    Article • Autophagy, June 2018, Taylor & Francis

    Dr Fumiyo Ikeda

  2. Linear ubiquitin chain-binding domains

    Article • FEBS Journal, April 2018, Wiley

    Dr Fumiyo Ikeda

  3. The anti-apoptosis ubiquitin E3 ligase XIAP promotes autophagosome-lysosome fusion during autophagy

    Article • March 2018, Cold Spring Harbor Laboratory Press

    Dr Fumiyo Ikeda

  4. The IAP family member BRUCE regulates autophagosome–lysosome fusion

    Article • Nature Communications, February 2018, Springer Science + Business Media

    Dr Fumiyo Ikeda

  5. Ubiquitin enzymes in the regulation of immune responses

    Article • Critical Reviews in Biochemistry and Molecular Biology, May 2017, Taylor & Francis

    Dr Fumiyo Ikeda

  6. Linear ubiquitin chains: enzymes, mechanisms and biology

    Article • Open Biology, April 2017, Royal Society Publishing

    Dr Fumiyo Ikeda

  7. Linear ubiquitination by LUBEL has a role inDrosophilaheat stress response

    Article • EMBO Reports, October 2016, EMBO

    Dr Fumiyo Ikeda

  8. The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate

    Article • Cell Reports, September 2016, Elsevier

    Dr Fumiyo Ikeda

  9. Inhibition of CBLB protects from lethal Candida albicans sepsis

    Article • Nature Medicine, July 2016, Springer Science + Business Media

    Dr Fumiyo Ikeda

  10. The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate

    Article • Cell Reports, May 2016, Elsevier

    Dr Fumiyo Ikeda

  11. An Essential Role for SHARPIN in the Regulation of Caspase 1 Activity in Sepsis

    Article • American Journal Of Pathology, May 2016, Elsevier

    Dr Fumiyo Ikeda

  12. Regulation of transcriptional network system during bone and cartilage development

    Article • Journal of Oral Biosciences, November 2015, Elsevier

    Dr Fumiyo Ikeda

  13. Linear ubiquitination signals in adaptive immune responses

    Article • Immunological Reviews, June 2015, Wiley

    Dr Fumiyo Ikeda

  14. New Insights into the Role of Ubiquitin Networks in the Regulation of Antiapoptosis Pathways

    Article • January 2015, Elsevier

    Dr Fumiyo Ikeda

  15. Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis

    Article • eLife, December 2014, eLife

    Dr Fumiyo Ikeda

  16. The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells

    Article • Nature, February 2014, Springer Science + Business Media

    Dr Fumiyo Ikeda

  17. Signal transduction and signaling networks

    Article • Molecular Biology of the Cell, March 2013, American Society for Cell Biology (ASCB)

    Dr Fumiyo Ikeda

  18. Fumiyo Ikeda: Ubiquitin lines up for action

    Article • The Journal of Cell Biology, October 2012, Rockefeller University Press

    Dr Fumiyo Ikeda

  19. Analysis of Nuclear Factor-κB (NF-κB) Essential Modulator (NEMO) Binding to Linear and Lysine-linked Ubiquitin Chains and Its Role in the Activation of NF-κB

    Article • Journal of Biological Chemistry, May 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Fumiyo Ikeda

  20. SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

    Article • Nature, March 2011, Springer Science + Business Media

    Dr Fumiyo Ikeda

  21. What Determines the Specificity and Outcomes of Ubiquitin Signaling?

    Article • Cell, November 2010, Elsevier

    Dr Fumiyo Ikeda

  22. Selective Binding of Linear Ubiquitin Chains to NEMO in NF-kappaB Activation

    Article • October 2010, Springer Science + Business Media

    Simin Rahighi, Dr Fumiyo Ikeda

  23. JNK/c-Jun Signaling Mediates an Anti-Apoptotic Effect of RANKL in Osteoclasts

    Article • Journal of Bone and Mineral Research, December 2009, Wiley

    Dr Fumiyo Ikeda

  24. Cbp Recruitment of Csk Into Lipid Rafts is Critical to c-Src Kinase Activity and Bone Resorption in Osteoclasts

    Article • Journal of Bone and Mineral Research, October 2009, Wiley

    Dr Fumiyo Ikeda

  25. Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation

    Article • Cell, March 2009, Elsevier

    Simin Rahighi, Dr Fumiyo Ikeda

  26. Paraspeckle protein p54nrb links Sox9-mediated transcription with RNA processing during chondrogenesis in mice

    Article • Journal of Clinical Investigation, September 2008, American Society for Clinical Investigation

    Dr Fumiyo Ikeda

  27. Atypical ubiquitin chains: new molecular signals. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

    Article • EMBO Reports, June 2008, EMBO

    Dr Fumiyo Ikeda

  28. Signal transduction and transcriptional regulation during mesenchymal cell differentiation

    Article • Journal of Bone and Mineral Metabolism, May 2008, Springer Science + Business Media

    Dr Fumiyo Ikeda

  29. Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-κB activation

    Article • The EMBO Journal, January 2008, Wiley

    Dr Fumiyo Ikeda

  30. Ubiquitin binding mediates the NF-κB inhibitory potential of ABIN proteins

    Article • Oncogene, January 2008, Springer Science + Business Media

    Dr Fumiyo Ikeda

  31. Ubiquitin signals in the NF-κB pathway: Figure 1

    Article • Biochemical Society Transactions, November 2007, Portland Press Ltd.

    Dr Fumiyo Ikeda

  32. Ihh/Gli2 Signaling Promotes Osteoblast Differentiation by Regulating Runx2 Expression and Function

    Article • Molecular Biology of the Cell, July 2007, American Society for Cell Biology (ASCB)

    Dr Fumiyo Ikeda

  33. Involvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genes

    Article • The EMBO Journal, June 2007, Wiley

    Dr Fumiyo Ikeda

  34. Critical role of cortactin in actin ring formation and osteoclastic bone resorption

    Article • Journal of Bone and Mineral Metabolism, August 2006, Springer Science + Business Media

    Dr Fumiyo Ikeda

  35. Activation of NFAT Signal In Vivo Leads to Osteopenia Associated with Increased Osteoclastogenesis and Bone-Resorbing Activity

    Article • The Journal of Immunology, August 2006, The American Association of Immunologists

    Dr Fumiyo Ikeda

  36. CYLD in Ubiquitin Signaling and Tumor Pathogenesis

    Article • Cell, May 2006, Elsevier

    Dr Fumiyo Ikeda

  37. Preferential inhibition of bone metastases by 5'-deoxy-5-fluorouridine and capecitabine in the 4T1/luc mouse breast cancer model

    Article • Oncology Reports, September 2005, Spandidos Publications

    Dr Fumiyo Ikeda

  38. A CCAAT/Enhancer Binding Protein β Isoform, Liver-Enriched Inhibitory Protein, Regulates Commitment of Osteoblasts and Adipocytes

    Article • Molecular and Cellular Biology, March 2005, ASM Journals

    Dr Fumiyo Ikeda

  39. Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation

    Article • Journal of Clinical Investigation, August 2004, American Society for Clinical Investigation

    Dr Fumiyo Ikeda

  40. Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation

    Article • Journal of Clinical Investigation, August 2004, American Society for Clinical Investigation

    Dr Fumiyo Ikeda, Dr. Sakae Tanaka

  41. Reciprocal Roles of Msx2 in Regulation of Osteoblast and Adipocyte Differentiation

    Article • Journal of Biological Chemistry, June 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Fumiyo Ikeda

  42. Effects of oral UFT combined with or without zoledronic acid on bone metastasis in the 4T1/luc mouse breast cancer

    Article • International Journal of Cancer, August 2003, Wiley

    Dr Fumiyo Ikeda

  43. Differential Roles of Smad1 and p38 Kinase in Regulation of Peroxisome Proliferator-activating Receptor γ during Bone Morphogenetic Protein 2-induced Adipogenesis

    Article • Molecular Biology of the Cell, February 2003, American Society for Cell Biology (ASCB)

    Dr Fumiyo Ikeda

  44. The role of SMADS in BMP signaling

    Article • Frontiers in Bioscience, January 2003, Frontiers in Bioscience

    Dr Fumiyo Ikeda