All Stories

  1. SARS-CoV-2 nsp3 and nsp4 are minimal constituents of a pore spanning replication organelle
  2. BA.1/BA.5 Immunogenicity, Reactogenicity, and Disease Activity after COVID-19 Vaccination in Patients with ANCA-Associated Vasculitis: A Prospective Observational Cohort Study
  3. Endosomal egress and intercellular transmission of hepatic ApoE-containing lipoproteins and its exploitation by the hepatitis C virus
  4. Structural conservation of HBV-like capsid proteins over hundreds of millions of years despite the shift from non-enveloped to enveloped life-style
  5. Effect of variants in LGP2 on MDA5-mediated activation of interferon response and suppression of hepatitis D virus replication
  6. Multi-Channel Colocalization Analysis and Visualization of Viral Proteins in Fluorescence Microscopy Images
  7. Endosomal egress and intercellular transmission of hepatic ApoE-containing lipoproteins and its exploitation by the hepatitis C virus
  8. A snapshot of protein trafficking in SARS‐CoV‐2 infection
  9. SARS-CoV-2 nsp3-4 suffice to form a pore shaping replication organelles
  10. Dual role of neddylation in transcription of hepatitis B virus RNAs from cccDNA and production of viral surface antigen
  11. Hepatitis D virus-induced interferon response and administered interferons control cell division-mediated virus spread
  12. Impaired Neutralizing Antibody Activity against B.1.617.2 (Delta) after Anti-SARS-CoV-2 Vaccination in Patients Receiving Anti-CD20 Therapy
  13. Redesigning of the cap conformation and symmetry of the diphenylethyne core to yield highly potent pan-genotypic NS5A inhibitors with high potency and high resistance barrier
  14. Genome-Wide CRISPR Screen Identifies RACK1 as a Critical Host Factor for Flavivirus Replication
  15. The Biogenesis of Dengue Virus Replication Organelles Requires the ATPase Activity of Valosin-Containing Protein
  16. Determinants in Nonstructural Protein 4A of Dengue Virus Required for RNA Replication and Replication Organelle Biogenesis
  17. Dengue virus is sensitive to inhibition prior to productive replication
  18. TLR3 Activation by Zika Virus Stimulates Inflammatory Cytokine Production Which Dampens the Antiviral Response Induced by RIG-I-Like Receptors
  19. Can we predict antibody responses in SARS-CoV-2? A cohort analysis
  20. A Versatile Reporter System To Monitor Virus-Infected Cells and Its Application to Dengue Virus and SARS-CoV-2
  21. Dimer Organization of Membrane‐Associated NS5A of Hepatitis C Virus as Determined by Highly Sensitive 1 H‐Detected Solid‐State NMR
  22. Dimer Organization of Membrane‐Associated NS5A of Hepatitis C Virus as Determined by Highly Sensitive 1 H‐Detected Solid‐State NMR
  23. SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography
  24. A Novel Cis-Acting RNA Structural Element Embedded in the Core Coding Region of the Hepatitis C Virus Genome Directs Internal Translation Initiation of the Overlapping Core+1 ORF
  25. A versatile reporter system to monitor virus infected cells and its application to dengue virus and SARS-CoV-2
  26. SARS-CoV-2 structure and replication characterized byin situcryo-electron tomography
  27. Proton‐Detected Solid‐State NMR of the Cell‐Free Synthesized α‐Helical Transmembrane Protein NS4B from Hepatitis C Virus
  28. Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation
  29. A Recurrent Neural Network for Particle Tracking in Microscopy Images Using Future Information, Track Hypotheses, and Multiple Detections
  30. ER-shaping atlastin proteins act as central hubs to promote flavivirus replication and virion assembly
  31. RACK1 mediates rewiring of intracellular networks induced by hepatitis C virus infection
  32. Prodrug Activation by a Viral Protease: Evaluating Combretastatin Peptide Hybrids To Selectively Target Infected Cells
  33. A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle
  34. Synthesis, Biological Evaluation, and Molecular Docking of Combretastatin and Colchicine Derivatives and their hCE1‐Activated Prodrugs as Antiviral Agents
  35. Discovery of highly divergent lineages of plant-associated astro-like viruses sheds light on the emergence of potyviruses
  36. The Role of Tissue Oxygen Tension in Dengue Virus Replication
  37. mRNAs biotinylated within the 5′ cap and protected against decapping: new tools to capture RNA–protein complexes
  38. Novel non-heteroarylpyrimidine (HAP) capsid assembly modifiers have a different mode of action from HAPs in vitro
  39. A Reverse Genetics System for Zika Virus Based on a Simple Molecular Cloning Strategy
  40. HBV Bypasses the Innate Immune Response and Does Not Protect HCV From Antiviral Activity of Interferon
  41. Hepatitis C virus-induced natural killer cell proliferation involves monocyte-derived cells and the OX40/OX40L axis
  42. Glycine-zipper motifs in hepatitis C virus nonstructural protein 4B are required for the establishment of viral replication organelles
  43. Optimization of Substrate-Analogue Furin Inhibitors
  44. Membrane alterations induced by nonstructural proteins of human norovirus
  45. Hepatitis C Virus Replication Depends on Endosomal Cholesterol Homeostasis
  46. Host-directed therapies for bacterial and viral infections
  47. Deciphering the Origin and Evolution of Hepatitis B Viruses by Means of a Family of Non-enveloped Fish Viruses
  48. Genome packaging of reovirus is mediated by the scaffolding property of the microtubule network
  49. Immune-mediated effects targeting hepatitis C virus in a syngeneic replicon cell transplantation mouse model
  50. Overall Structural Model of NS5A Protein from Hepatitis C Virus and Modulation by Mutations Confering Resistance of Virus Replication to Cyclosporin A
  51. Erratum for Roth et al., “Flavivirus Infection Uncouples Translation Suppression from Cellular Stress Responses”
  52. Maturation of secreted HCV particles by incorporation of secreted ApoE protects from antibodies by enhancing infectivity
  53. Novel nucleoside analogues targeting HCV replication through an NS5A-dependent inhibition mechanism
  54. Phosphorylation-Dependent Feedback Inhibition of RIG-I by DAPK1 Identified by Kinome-wide siRNA Screening
  55. Ultrastructural Characterization of Zika Virus Replication Factories
  56. Flavivirus Infection Uncouples Translation Suppression from Cellular Stress Responses
  57. Effects of NS2B-NS3 protease and furin inhibition on West Nile and Dengue virus replication
  58. Chronic viral hepatitis and its association with liver cancer
  59. Editorial: An expanded view of viruses
  60. Peptide–Boronic Acid Inhibitors of Flaviviral Proteases: Medicinal Chemistry and Structural Biology
  61. The quest for host targets to combat dengue virus infections
  62. Broad neutralization of hepatitis C virus-resistant variants by Civacir hepatitis C immunoglobulin
  63. Hepatitis C Virus—From Discovery to Cure
  64. Corrigendum: Conserved RNA secondary structures and long-range interactions in hepatitis C viruses
  65. Dengue Virus Perturbs Mitochondrial Morphodynamics to Dampen Innate Immune Responses
  66. Reovirus intermediate subviral particles constitute a strategy to infect intestinal epithelial cells by exploiting TGF-β dependent pro-survival signaling
  67. A Slow Maturation Process Renders Hepatitis B Virus Infectious
  68. Endoplasmic Reticulum: The Favorite Intracellular Niche for Viral Replication and Assembly
  69. Cell-free expression, purification, and membrane reconstitution for NMR studies of the nonstructural protein 4B from hepatitis C virus
  70. Correlative light and electron microscopy methods for the study of virus-cell interactions
  71. Type I and type II interferon responses in two human liver cell lines (Huh-7 and HuH6)
  72. Interferon‐inducible cholesterol‐25‐hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation
  73. Alleviation of off-target effects from vector-encoded shRNAs via codelivered RNA decoys
  74. A Proline-Tryptophan Turn in the Intrinsically Disordered Domain 2 of NS5A Protein Is Essential for Hepatitis C Virus RNA Replication
  75. P147: A phenotypic NS3-protease inhibitor resistance assay to characterize resistance-associated mutations in patients
  76. P117: Hepatitis C Virus mediates NRG1-dependent down-regulation of ErbB3, thereby modifies ErbB receptor family composition at the cell surface
  77. P119: Hepatitis C virus inhibits IL-1 β -induced Iк Bζ expression and thereby antagonizes mechanisms which may affect cell proliferation
  78. P096: Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication via blockage of membranous web formation
  79. P118: The Hepatitis C Virus (HCV) facilitates CXCR2 ligand expression in response to the Epidermal Growth Factor (EGF) and is able to induce the EGF production by an autocrine circuit in its host cell
  80. Dengue Virus Inhibition of Autophagic Flux and Dependency of Viral Replication on Proteasomal Degradation of the Autophagy Receptor p62
  81. Conserved RNA secondary structures and long-range interactions in hepatitis C viruses
  82. A Combined Genetic-Proteomic Approach Identifies Residues within Dengue Virus NS4B Critical for Interaction with NS3 and Viral Replication
  83. Hepatitis C virus infection inhibits P-body granule formation in human livers
  84. Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody
  85. A Conserved NS3 Surface Patch Orchestrates NS2 Protease Stimulation, NS5A Hyperphosphorylation and HCV Genome Replication
  86. A monocytic detour to replicate patient‐derived hepatitis C virus in hepatoma cells and its use for phenotypic analyses
  87. Expression of the Novel Hepatitis C Virus Core+1/ARF Protein in the Context of JFH1-Based Replicons
  88. A sensor at the lipid‐protein interface: Lipid peroxidation controls hepatitis C virus replication
  89. Identification of HNRNPK as Regulator of Hepatitis C Virus Particle Production
  90. Wheat germ cell-free expression: Two detergents with a low critical micelle concentration allow for production of soluble HCV membrane proteins
  91. Novel Dengue Virus NS2B/NS3 Protease Inhibitors
  92. Aminoterminal Amphipathic α-Helix AH1 of Hepatitis C Virus Nonstructural Protein 4B Possesses a Dual Role in RNA Replication and Virus Production
  93. Daclatasvir-Like Inhibitors of NS5A Block Early Biogenesis of Hepatitis C Virus–Induced Membranous Replication Factories, Independent of RNA Replication
  94. Hepatitis C Virus RNA Replication and Assembly: Living on the Fat of the Land
  95. Development of a high-throughput pyrosequencing assay for monitoring temporal evolution and resistance associated variant emergence in the Hepatitis C virus protease coding-region
  96. Apolipoprotein E Likely Contributes to a Maturation Step of Infectious Hepatitis C Virus Particles and Interacts with Viral Envelope Glycoproteins
  97. The lysine methyltransferase SMYD3 interacts with hepatitis C virus NS5A and is a negative regulator of viral particle production
  98. Characterization of the Mode of Action of a Potent Dengue Virus Capsid Inhibitor
  99. Membranous Replication Factories Induced by Plus-Strand RNA Viruses
  100. Strategies to Inhibit Entry of HBV and HDV Into Hepatocytes
  101. Matrix Conditions and KLF2-Dependent Induction of Heme Oxygenase-1 Modulate Inhibition of HCV Replication by Fluvastatin
  102. Inhibition of HCV Replication by Cyclophilin Antagonists Is Linked to Replication Fitness and Occurs by Inhibition of Membranous Web Formation
  103. Heterologous Src Homology 4 Domains Support Membrane Anchoring and Biological Activity of HIV-1 Nef
  104. Targets for Antiviral Therapy of Hepatitis C
  105. Dengue Virus- and Hepatitis C Virus-Induced Replication and Assembly Compartments: the Enemy Inside--Caught in the Web
  106. Perilipin discerns chronic from acute hepatocellular steatosis
  107. Revisiting Dengue Virus–Host Cell Interaction
  108. On the History of Hepatitis C Virus Cell Culture Systems
  109. Thiazolidinone–Peptide Hybrids as Dengue Virus Protease Inhibitors with Antiviral Activity in Cell Culture
  110. Hepatitis C: A mouse at the end of the tunnel
  111. Robust RNAi enhancement via human Argonaute-2 overexpression from plasmids, viral vectors and cell lines
  112. Membrane undulation induced by NS4A of Dengue virus: a molecular dynamics simulation study
  113. Replication Vesicles are Load- and Choke-Points in the Hepatitis C Virus Lifecycle
  114. Morphological and Biochemical Characterization of the Membranous Hepatitis C Virus Replication Compartment
  115. The Interactomes of Influenza Virus NS1 and NS2 Proteins Identify New Host Factors and Provide Insights for ADAR1 Playing a Supportive Role in Virus Replication
  116. Hepatitis C virus core+1/ARF protein decreases hepcidin transcription through an AP1 binding site
  117. Evidence for Novel Hepaciviruses in Rodents
  118. The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection
  119. The Lipid Kinase Phosphatidylinositol-4 Kinase III Alpha Regulates the Phosphorylation Status of Hepatitis C Virus NS5A
  120. Three-Dimensional Architecture of Tick-Borne Encephalitis Virus Replication Sites and Trafficking of the Replicated RNA
  121. Nuclear Localization of Dengue Virus Nonstructural Protein 5 Does Not Strictly Correlate with Efficient Viral RNA Replication and Inhibition of Type I Interferon Signaling
  122. Analysis of hepatitis C virus resistance to silibinin in vitro and in vivo points to a novel mechanism involving nonstructural protein 4B
  123. Factors That Determine the Antiviral Efficacy of HCV-Specific CD8+ T Cells Ex Vivo
  124. Virion Assembly and Release
  125. Liver Injury and Disease Pathogenesis in Chronic Hepatitis C
  126. Hepatitis C Virus-Specific Directly Acting Antiviral Drugs
  127. Adaptive Immune Responses in Hepatitis C Virus Infection
  128. Animal Models for Hepatitis C
  129. Cell Culture Systems for Hepatitis C Virus
  130. Hepatitis C Virus Proteins: From Structure to Function
  131. Hepatitis C Virus RNA Replication
  132. Hepatitis C Virus RNA Translation
  133. Hepatitis C Virus Replicons Volume 3 and 4
  134. Inhibition of hepatitis C virus RNA translation by antisense bile acid conjugated phosphorothioate modified oligodeoxynucleotides (ODN)
  135. Innate Immune Responses to Hepatitis C Virus
  136. The Origin of Hepatitis C Virus
  137. Treatment of Chronic Hepatitis C: Current and Future
  138. Low Oxygen Tension Enhances Hepatitis C Virus Replication
  139. Three-Dimensional Architecture and Biogenesis of Membrane Structures Associated with Hepatitis C Virus Replication
  140. A Novel Inhibitor of Dengue Virus Replication That Targets the Capsid Protein
  141. Identification of type I and type II interferon-induced effectors controlling hepatitis C virus replication
  142. TCR-Redirected Human T Cells Inhibit Hepatitis C Virus Replication: Hepatotoxic Potential Is Linked to Antigen Specificity and Functional Avidity
  143. Characterization of Hepatitis C Virus Particle Subpopulations Reveals Multiple Usage of the Scavenger Receptor BI for Entry Steps
  144. Reconstitution of the Entire Hepatitis C Virus Life Cycle in Nonhepatic Cells
  145. Persistence of HCV in Quiescent Hepatic Cells Under Conditions of an Interferon-Induced Antiviral Response
  146. MAP-Kinase Regulated Cytosolic Phospholipase A2 Activity Is Essential for Production of Infectious Hepatitis C Virus Particles
  147. Viral immune modulators perturb the human molecular network by common and unique strategies
  148. A Plant-Derived Flavonoid Inhibits Entry of All HCV Genotypes Into Human Hepatocytes
  149. Mutations That Alter Use of Hepatitis C Virus Cell Entry Factors Mediate Escape From Neutralizing Antibodies
  150. Failure of innate and adaptive immune responses in controlling hepatitis C virus infection
  151. Persistent intracellular pathogens
  152. High plasma level of nucleocapsid-free envelope glycoprotein-positive lipoproteins in hepatitis C patients
  153. miRNA-130a Targets ATG2B and DICER1 to Inhibit Autophagy and Trigger Killing of Chronic Lymphocytic Leukemia Cells
  154. Promotion of Hepatocellular Carcinoma by Hepatitis C Virus
  155. New targets for antiviral therapy of chronic hepatitis C
  156. Normalizing for individual cell population context in the analysis of high-content cellular screens
  157. Generation of T-cell receptors targeting a genetically stable and immunodominant cytotoxic T-lymphocyte epitope within hepatitis C virus non-structural protein 3
  158. Mouse Hepatic Cells Support Assembly of Infectious Hepatitis C Virus Particles
  159. Exploitation of cellular pathways by Dengue virus
  160. Molecular Mechanism of Signal Perception and Integration by the Innate Immune Sensor Retinoic Acid-inducible Gene-I (RIG-I)
  161. A Concerted Action of Hepatitis C Virus P7 and Nonstructural Protein 2 Regulates Core Localization at the Endoplasmic Reticulum and Virus Assembly
  162. Inhibition of hepatitis C virus gene expression by adenoviral vectors encoding antisense RNA in vitro and in vivo
  163. Die molekularen Mechanismen der Replikation des Hepatitis C Virus – Implikationen für die Entwicklung antiviraler Wirkstoffe
  164. Synthesis and biological evaluation of α-ketoamides as inhibitors of the Dengue virus protease with antiviral activity in cell-culture
  165. Domain 3 of NS5A Protein from the Hepatitis C Virus Has Intrinsic α-Helical Propensity and Is a Substrate of Cyclophilin A
  166. Interleukin‐32: A new proinflammatory cytokine involved in hepatitis C virus‐related liver inflammation and fibrosis
  167. NS4B Self-Interaction through Conserved C-Terminal Elements Is Required for the Establishment of Functional Hepatitis C Virus Replication Complexes
  168. C-Src is required for complex formation between the hepatitis C virus-encoded proteins NS5A and NS5B: A prerequisite for replication
  169. Hepatitis c virus and host cell lipids: An intimate connection
  170. Assembly of infectious hepatitis C virus particles
  171. A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strain JFH1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture across Genotypes
  172. Biochemical and Morphological Properties of Hepatitis C Virus Particles and Determination of Their Lipidome
  173. Recruitment and Activation of a Lipid Kinase by Hepatitis C Virus NS5A Is Essential for Integrity of the Membranous Replication Compartment
  174. Structural and Functional Studies of Nonstructural Protein 2 of the Hepatitis C Virus Reveal Its Key Role as Organizer of Virion Assembly
  175. Experimental models to study the immunobiology of hepatitis C virus
  176. Comparative Analysis of the Lambda-Interferons IL-28A and IL-29 regarding Their Transcriptome and Their Antiviral Properties against Hepatitis C Virus
  177. DEB025 (Alisporivir) Inhibits Hepatitis C Virus Replication by Preventing a Cyclophilin A Induced Cis-Trans Isomerisation in Domain II of NS5A
  178. New Insights into Structure and Replication of the Hepatitis C Virus and Clinical Implications
  179. Production of Infectious Hepatitis C Virus in Primary Cultures of Human Adult Hepatocytes
  180. A Major Determinant of Cyclophilin Dependence and Cyclosporine Susceptibility of Hepatitis C Virus Identified by a Genetic Approach
  181. Detecting host factors involved in virus infection by observing the clustering of infected cells in siRNA screening images
  182. Hepatitis C virus replication cycle
  183. Deregulation of miR-92a expression is implicated in hepatocellular carcinoma development
  184. Role of Annexin A2 in the Production of Infectious Hepatitis C Virus Particles
  185. Mouse-Specific Residues of Claudin-1 Limit Hepatitis C Virus Genotype 2a Infection in a Human Hepatocyte Cell Line
  186. The heme oxygenase 1 product biliverdin interferes with hepatitis C virus replication by increasing antiviral interferon response
  187. Role of RNA Structures in Genome Terminal Sequences of the Hepatitis C Virus for Replication and Assembly
  188. Cyclosporine A inhibits hepatitis C virus nonstructural protein 2 through cyclophilin A
  189. Characterization of Determinants Important for Hepatitis C Virus p7 Function in Morphogenesis by Using trans-Complementation
  190. Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics
  191. A reporter cell line for rapid and sensitive evaluation of hepatitis C virus infectivity and replication
  192. Reconstructing signaling pathways from RNAi data using probabilistic Boolean threshold networks
  193. Production of Infectious Genotype 1b Virus Particles in Cell Culture and Impairment by Replication Enhancing Mutations
  194. Hepatitis C Virus NS5A Protein Is a Substrate for the Peptidyl-prolyl cis/trans Isomerase Activity of Cyclophilins A and B
  195. Investigation of a role for lysine residues in non-structural proteins 2 and 2/3 of the hepatitis C virus for their degradation and virus assembly
  196. Analysis of CD8+ T-Cell–Mediated Inhibition of Hepatitis C Virus Replication Using a Novel Immunological Model
  197. Composition and Three-Dimensional Architecture of the Dengue Virus Replication and Assembly Sites
  198. Single-cell-based image analysis of high-throughput cell array screens for quantification of viral infection
  199. Hepatitis B and C virus coinfection: A novel model system reveals the absence of direct viral interference
  200. Moving closer to a mouse model for hepatitis C
  201. Nonstructural 3/4A protease of hepatitis C virus activates epithelial growth factor-induced signal transduction by cleavage of the T-cell protein tyrosine phosphatase
  202. Secretion of Hepatitis C Virus Envelope Glycoproteins Depends on Assembly of Apolipoprotein B Positive Lipoproteins
  203. Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27–restricted human immune response
  204. Hepatitis C virus replicons: dinosaurs still in business?
  205. Neutralizing Host Responses in Hepatitis C Virus Infection Target Viral Entry at Postbinding Steps and Membrane Fusion
  206. Sustained delivery of siRNAs targeting viral infection by cell-degradable multilayered polyelectrolyte films
  207. Structural and Functional Characterization of Nonstructural Protein 2 for Its Role in Hepatitis C Virus Assembly
  208. Role of the Hepatitis C Virus Core+1 Open Reading Frame and Core cis-Acting RNA Elements in Viral RNA Translation and Replication
  209. Comparative In Vitro Anti-Hepatitis C Virus Activities of a Selected Series of Polymerase, Protease, and Helicase Inhibitors
  210. Efficient trans-Encapsidation of Hepatitis C Virus RNAs into Infectious Virus-Like Particles
  211. Identification of Terfenadine as an Inhibitor of Human CD81-Receptor HCV-E2 Interaction: Synthesis and Structure Optimization
  212. Molecular aspects of Dengue virus replication
  213. Essential Role of Domain III of Nonstructural Protein 5A for Hepatitis C Virus Infectious Particle Assembly
  214. Enhancement of genotype 1 hepatitis C virus replication by bile acids through FXR
  217. Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81
  218. The Lipid Droplet Binding Domain of Hepatitis C Virus Core Protein Is a Major Determinant for Efficient Virus Assembly
  219. Erratum
  220. Cell Culture Adaptation of Hepatitis C Virus and In Vivo Viability of an Adapted Variant
  221. The lipid droplet is an important organelle for hepatitis C virus production
  222. A Tribute to a Colleague
  223. Hepatitis C virus molecular clones and their replication capacity in vivo and in cell culture
  224. Hepatitis C virus escape from the interferon regulatory factor 3 pathway by a passive and active evasion strategy
  225. Hepatitis viruses in the XXI century
  226. Hepatitis C Virus p7 Protein Is Crucial for Assembly and Release of Infectious Virions
  227. Analysis of Hepatitis C Virus Superinfection Exclusion by Using Novel Fluorochrome Gene-Tagged Viral Genomes
  228. The Cyclophilin Inhibitor Debio-025 is a Potent Inhibitor of Hepatitis C Virus Replication in vitro With a Unique Resistance Profile
  229. Identification of Determinants Involved in Initiation of Hepatitis C Virus RNA Synthesis by Using Intergenotypic Replicase Chimeras
  230. The Non-structural Protein 4A of Dengue Virus Is an Integral Membrane Protein Inducing Membrane Alterations in a 2K-regulated Manner
  231. Analysis of Hepatitis C Virus Superinfection Exclusion by Using Novel Fluorochrome Gene-Tagged Viral Genomes
  232. euHCVdb: the European hepatitis C virus database
  233. Antiviral effects of amantadine and iminosugar derivatives against hepatitis C virus
  234. The Level of CD81 Cell Surface Expression Is a Key Determinant for Productive Entry of Hepatitis C Virus into Host Cells
  235. Ribavirin Antagonizes the In Vitro Anti-Hepatitis C Virus Activity of 2′-C-Methylcytidine, the Active Component of Valopicitabine
  236. The Hepatitis C Virus RNA 3′-Untranslated Region Strongly Enhances Translation Directed by the Internal Ribosome Entry Site
  237. Production of infectious hepatitis C virus particles in three-dimensional cultures of the cell line carrying the genome-length dicistronic viral RNA of genotype 1b
  238. Hepatitis C virus molecular clones: from cDNA to infectious virus particles in cell culture
  239. HCV proteins increase expression of heme oxygenase-1 (HO-1) and decrease expression of Bach1 in human hepatoma cells
  240. Characterization of the Early Steps of Hepatitis C Virus Infection by Using Luciferase Reporter Viruses
  241. Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras
  242. High Density Lipoprotein Inhibits Hepatitis C Virus-neutralizing Antibodies by Stimulating Cell Entry via Activation of the Scavenger Receptor BI
  243. From Structure to Function: New Insights into Hepatitis C Virus RNA Replication
  244. 417 Subgenomic hepatitis C replicon deriving from a clinical isolate with virologic non-response to IFN-based therapy and IFN resistance in vitro
  245. Subcellular Localization and Membrane Topology of the Dengue Virus Type 2 Non-structural Protein 4B
  246. Relation between viral fitness and immune escape within the hepatitis C virus protease
  247. The face of future hepatitis C antiviral drug development: Recent biological and virologic advances and their translation to drug development and clinical practice
  248. O.137 HDL inhibits neutralisation by HCV antibodies via a ternary interaction with the scavenger receptor BI
  249. O.171 HDL inhibits HCV neutralisation by CD81-NOB antibodies by stimulating cell entry through activation of the scavenger receptor BI
  250. The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replicationin vitro
  251. Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33
  252. O.067 Hepatitis C virus: Virology, immunology, natural history, treatment
  253. Quantitative Analysis of the Hepatitis C Virus Replication Complex
  254. Dissecting the Interferon-Induced Inhibition of Hepatitis C Virus Replication by Using a Novel Host Cell Line
  255. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
  256. Hepatitis C Virus NS2/3 Processing Is Required for NS3 Stability and Viral RNA Replication
  257. Erratum: Corrigendum: Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
  258. The hepatitis C virus replicon system: From basic research to clinical application
  259. Efficient hepatitis C virus cell culture system: What a difference the host cell makes
  260. Hepatitis C Virus-Replicating Hepatocytes Induce Fibrogenic Activation of Hepatic Stellate Cells
  261. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
  262. Hepatitis C virus core triggers apoptosis in liver cells by inducing ER stress and ER calcium depletion
  263. Mutational Analysis of Hepatitis C Virus Nonstructural Protein 5A: Potential Role of Differential Phosphorylation in RNA Replication and Identification of a Genetically Flexible Domain
  264. Efficient Rescue of Hepatitis C Virus RNA Replication by trans-Complementation with Nonstructural Protein 5A
  265. Kissing-Loop Interaction in the 3′ End of the Hepatitis C Virus Genome Essential for RNA Replication
  266. Membrane Association of the RNA-Dependent RNA Polymerase Is Essential for Hepatitis C Virus RNA Replication
  267. Interferon type I gene expression in chronic hepatitis C
  268. Structure and Function of the Membrane Anchor Domain of Hepatitis C Virus Nonstructural Protein 5A
  269. Targeting of Hepatitis C Virus Core Protein to Mitochondria through a Novel C-Terminal Localization Motif
  270. Alternative Approaches for Efficient Inhibition of Hepatitis C Virus RNA Replication by Small Interfering RNAs
  271. Novel Insights into Hepatitis C Virus Replication and Persistence
  272. Replication of the hepatitis C virus in cell culture
  273. A replicon-based bioassay for the measurement of interferons in patients with chronic hepatitis C
  274. Identification of the Hepatitis C Virus RNA Replication Complex in Huh-7 Cells Harboring Subgenomic Replicons
  275. Hepatitis C virus RNA replication is resistant to tumour necrosis factor-α
  276. Viral and Cellular Determinants of Hepatitis C Virus RNA Replication in Cell Culture
  277. Identification and characterization of amphiphysin II as a novel cellular interaction partner of the hepatitis C virus NS5A protein
  278. The Hepatitis C Virus RNA-Dependent RNA Polymerase Membrane Insertion Sequence Is a Transmembrane Segment
  279. Hepatitis C virus replicons: potential role for drug development
  280. Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees
  281. Genetic Analysis of Sequences in the 3′ Nontranslated Region of Hepatitis C Virus That Are Important for RNA Replication
  282. Serum versus intrahepatic HCV RNA and liver histology
  283. Persistent and Transient Replication of Full-Length Hepatitis C Virus Genomes in Cell Culture
  284. Interferon-γ inhibits replication of subgenomic and genomic hepatitis C virus RNAs
  285. Functional Properties of a Monoclonal Antibody Inhibiting the Hepatitis C Virus RNA-dependent RNA Polymerase
  286. Sequences in the 5′ Nontranslated Region of Hepatitis C Virus Required for RNA Replication
  287. Oral immunization with HCV-NS3—transformed Salmonella: Induction of HCV-specific CTL in a transgenic mouse model
  288. Novel cell culture systems for the hepatitis C virus
  289. Enhancement of Hepatitis C Virus RNA Replication by Cell Culture-Adaptive Mutations
  290. Characterization of Cell Lines Carrying Self-Replicating Hepatitis C Virus RNAs
  291. Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation
  292. Replication of the hepatitis C virus
  293. Replication of Subgenomic Hepatitis C Virus RNAs in a Hepatoma Cell Line
  294. The NS3/4A proteinase of the hepatitis C virus: unravelling structure and function of an unusual enzyme and a prime target for antiviral therapy
  295. Selective Stimulation of Hepatitis C Virus and Pestivirus NS5B RNA Polymerase Activity by GTP
  296. Detection of hepatitis C virus in paraffin-embedded liver biopsies of patients negative for viral RNA in serum
  297. Biochemical and Kinetic Analyses of NS5B RNA-Dependent RNA Polymerase of the Hepatitis C Virus
  298. Hepatitis B virus with antigenically altered hepatitis B surface antigen is selected by high-dose hepatitis B immune globulin after liver transplantation
  299. Determinants of Substrate Specificity in the NS3 Serine Proteinase of the Hepatitis C Virus
  300. Candidate Targets for Hepatitis C Virus-Specific Antiviral Therapy
  301. In VitroStudies on the Activation of the Hepatitis C Virus NS3 Proteinase by the NS4A Cofactor
  302. An in Vitro Assay for Hepatitis C Virus NS3 Serine Proteinase
  303. Mechanisms governing hepadnaviral nucleocapsid assembly
  304. Expression of the P-protein of the human hepatitis B virus in a vaccinia virus system and detection of the nucleocapsid-associated P-gene product by radiolabelling at newly introduced phosphorylation sites
  305. The duck hepatitis B virus P-gene codes for protein strongly associated with the 5′-end of the viral dna minus strand
  306. Adaptation of the Hepatitis C Virus to Cell Culture
  307. Chronic hepatitis C: Portrait of a silent epidemic and the etiologic agent
  308. In Vitro Replication Models