All Stories

  1. Recurrent integration of domestic cat hepatitis B virus DNA near feline CCNE1 supports an oncogenic role in hepatocellular carcinoma in cats

    Article • Tumour Virus Research, December 2025, Elsevier

    Thomas Tu

  2. Biology of hepatitis B virus DNA integration and its impact on antiviral R&D

    Article • Antiviral Research, December 2025, Elsevier

    Thomas Tu

  3. Patient and public health perspectives to inform expansion of hepatitis B treatment guidelines

    Article • The Lancet Gastroenterology & Hepatology, October 2025, Elsevier

    Thomas Tu

  4. Scientific and medical evidence informing expansion of hepatitis B treatment guidelines

    Article • The Lancet Gastroenterology & Hepatology, October 2025, Elsevier

    Thomas Tu

  5. Let's break it down: combating hepatitis stigma and discrimination

    Article • The Lancet Gastroenterology & Hepatology, September 2025, Elsevier

    Thomas Tu

  6. Sexual health and young people living with chronic hepatitis B: adopting a treatment as prevention framework

    Article • The Lancet Gastroenterology & Hepatology, July 2025, Elsevier

    Thomas Tu

  7. Domestic Cat Hepadnavirus, a Hepatitis B-like Virus Associated with Feline Liver Disease

    Article • Veterinary Clinics of North America Small Animal Practice, July 2025, Elsevier

    Thomas Tu

  8. Demographic factors, knowledge, and experiences associated with engagement in care in Australians diagnosed with hepatitis B

    Article • Discover Public Health, June 2025, Springer Science + Business Media

    Thomas Tu

  9. Domestic cat hepadnavirus is detected infrequently in feline blood and liver samples submitted for diagnostic testing in Texas, USA

    Article • Virology, June 2025, Elsevier

    Thomas Tu

  10. Twelfth scientific biennial meeting of the Australasian Virology Society: AVS12 2024

    Article • Journal of Virology, May 2025, ASM Journals

    Thomas Tu

  11. Best practices for engaging with affected communities: chronic hepatitis B as a case study

    Article • Infectious Diseases of Poverty, March 2025, Springer Science + Business Media

    Thomas Tu

  12. The urgent need to end hepatitis B stigma and discrimination

    Article • The Lancet Gastroenterology & Hepatology, February 2025, Elsevier

    Thomas Tu

  13. Novel digital droplet inverse PCR assay shows that natural clearance of hepatitis B infection is associated with fewer viral integrations

    Article • Emerging Microbes & Infections, January 2025, Taylor & Francis

    Thomas Tu

  14. HBV‐Induced Carcinogenesis: Mechanisms, Correlation With Viral Suppression, and Implications for Treatment

    Article • Liver International, December 2024, Wiley

    Thomas Tu

  15. Perspectives of People Living With Chronic Hepatitis D: Impact of Disease and Unmet Needs Along the Care Cascade

    Article • Journal of Viral Hepatitis, September 2024, Wiley

    Thomas Tu

  16. Hepatitis B Viral Protein HBx: Roles in Viral Replication and Hepatocarcinogenesis

    Article • Viruses, August 2024, MDPI AG

    Thomas Tu

  17. Major open questions in the hepatitis B and D field – Proceedings of the inaugural International emerging hepatitis B and hepatitis D researchers workshop

    Article • Virology, July 2024, Elsevier

    Thomas Tu

  18. Peer support for people living with hepatitis B virus—A foundation for treatment expansion

    Article • Journal of Viral Hepatitis, May 2024, Wiley

    Thomas Tu

  19. Highlights from the 2023 International Meeting on the Molecular Biology of Hepatitis B virus

    Article • Journal of General Virology, May 2024, Society for General Microbiology

    Thomas Tu

  20. Quality of life of people living with chronic hepatitis B: The role of social support system

    Article • PLOS Global Public Health, April 2024, PLOS

    Thomas Tu

  21. Hepatitis B Virus and Hepatitis C Virus Affect Mitochondrial Function Through Different Metabolic Pathways, Explaining Virus-Specific Clinical Features of Chronic Hepatitis

    Article • The Journal of Infectious Diseases, April 2024, Oxford University Press (OUP)

    Thomas Tu

  22. Inhibition of Cellular Factor TM6SF2 Suppresses Secretion Pathways of Hepatitis B, Hepatitis C, and Hepatitis D Viruses

    Article • The Journal of Infectious Diseases, February 2024, Oxford University Press (OUP)

    Thomas Tu

  23. Reply to Piewbang et al. Domestic Cat Hepadnavirus Antigens in Lymphoma Tissues. Comment on “Beatty et al. Domestic Cat Hepadnavirus and Lymphoma. Viruses 2023, 15, 2294”

    Article • Viruses, January 2024, MDPI AG

    Thomas Tu

  24. Domestic Cat Hepadnavirus and Pathogenic Retroviruses; A Sero-Molecular Survey of Cats in Santiago, Chile

    Article • Viruses, December 2023, MDPI AG

    Thomas Tu

  25. Letter to the Editor: Halting antiviral therapy in patients with cirrhosis and chronic hepatitis B: A dangerous game?

    Article • Hepatology, December 2023, Wolters Kluwer Health

    Thomas Tu

  26. Domestic Cat Hepadnavirus and Lymphoma

    Article • Viruses, November 2023, MDPI AG

    Thomas Tu

  27. Special Issue “Hepatitis B Virus: New Breakthroughs to Conquer an Ancient Disease”

    Article • Viruses, October 2023, MDPI AG

    Thomas Tu

  28. Targeting Hepatitis B Virus DNA Using Designer Gene Editors

    Article • Clinics in Liver Disease, July 2023, Elsevier

    Thomas Tu

  29. Novel Assays to Solve the Clinical and Scientific Challenges of Chronic Hepatitis B

    Article • Clinics in Liver Disease, July 2023, Elsevier

    Thomas Tu

  30. Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”

    Article • mBio, June 2023, ASM Journals

    Dr Robert A Edwards, Thomas Tu, Dr Subir Sarker

  31. Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”

    Article • mSphere, June 2023, ASM Journals

    Dr Robert A Edwards, Thomas Tu, Dr Subir Sarker

  32. Targeting liver metabolism: a pathway to cure hepatitis B virus?

    Article • Expert Review of Gastroenterology & Hepatology, June 2023, Taylor & Francis

    Thomas Tu

  33. Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”

    Article • Journal of Virology, May 2023, ASM Journals

    Dr Robert A Edwards, Thomas Tu, Dr Subir Sarker

  34. Pathway to global elimination of hepatitis B: HBV cure is just the first step

    Article • Hepatology, May 2023, Wolters Kluwer Health

    Thomas Tu

  35. Inhibition of cellular factor TM6SF2 suppresses secretion pathways of Hepatitis B, Hepatitis C and Hepatitis D viruses

    Article • April 2023, Research Square

    Thomas Tu

  36. Domestic Cat Hepadnavirus: Molecular Epidemiology and Phylogeny in Cats in Hong Kong

    Article • Viruses, January 2023, MDPI AG

    Thomas Tu

  37. Monitoring quality of care in hepatocellular carcinoma: A modified Delphi consensus

    Article • Hepatology Communications, September 2022, Wolters Kluwer Health

    Thomas Tu, Prof james O'Beirne

  38. Prevalence and Genomic Sequence Analysis of Domestic Cat Hepadnavirus in the United States

    Article • Viruses, September 2022, MDPI AG

    Thomas Tu

  39. Mitosis of hepatitis B virus-infected cells in vitro results in uninfected daughter cells

    Article • JHEP Reports, September 2022, Elsevier

    Thomas Tu

  40. Stigma: a major barrier to hepatitis B elimination

    Article • Nature Reviews Gastroenterology & Hepatology, August 2022, Springer Science + Business Media

    Thomas Tu

  41. Long-term hepatitis B virus infection of rhesus macaques requires suppression of host immunity

    Article • Nature Communications, May 2022, Springer Science + Business Media

    Thomas Tu

  42. Surrogate Markers for Hepatitis B Virus Covalently Closed Circular DNA

    Article • Seminars in Liver Disease, April 2022, Thieme Publishing Group

    Thomas Tu

  43. Approaches to quantifying hepatitis B virus covalently closed circular DNA

    Article • Clinical and Molecular Hepatology, April 2022, The Korean Association for the Study of the Liver (KAMJE)

    Thomas Tu

  44. Viral integrations in chronic hepatitis B infection: Purposeless passenger or problematic promoter of persistence?

    Article • Hepatology, March 2022, Wolters Kluwer Health

    Thomas Tu

  45. A River From the Liver: Detecting Hepatocyte Genomic DNA in Urine

    Article • Hepatology Communications, October 2021, Wolters Kluwer Health

    Thomas Tu

  46. The Inaugural Australian Centre for Hepatitis Virology Public Panel Discussion on Viral Hepatitis Research—Lessons in Scientific Community Outreach

    Article • Viruses, September 2021, MDPI AG

    Thomas Tu

  47. Viral Biomarkers for Hepatitis B Virus-Related Hepatocellular Carcinoma Occurrence and Recurrence

    Article • Frontiers in Microbiology, June 2021, Frontiers

    Thomas Tu

  48. De novo synthesis of hepatitis B virus nucleocapsids is dispensable for the maintenance and transcriptional regulation of cccDNA

    Article • JHEP Reports, February 2021, Elsevier

    Thomas Tu

  49. Hepatitis B Virus DNA Integration: In Vitro Models for Investigating Viral Pathogenesis and Persistence

    Article • Viruses, January 2021, MDPI AG

    Thomas Tu

  50. A sensitive and Specific PCR-based Assay to Quantify Hepatitis B Virus Covalently Closed Circular (ccc) DNA While Preserving Cellular DNA

    Article • BIO-PROTOCOL, January 2021, Bio-Protocol, LLC

    Thomas Tu

  51. Special Issue “Hepatitis B Virus Infection: From Diagnostics to Treatments”

    Article • Viruses, November 2020, MDPI AG

    Thomas Tu

  52. A novel method to precisely quantify hepatitis B virus covalently closed circular (ccc)DNA formation and maintenance

    Article • Antiviral Research, September 2020, Elsevier

    Thomas Tu

  53. The evolution and clinical impact of hepatitis B virus genome diversity

    Article • Nature Reviews Gastroenterology & Hepatology, May 2020, Springer Science + Business Media

    Thomas Tu

  54. The Lived Experience of Chronic Hepatitis B: A Broader View of Its Impacts and Why We Need a Cure

    Article • Viruses, May 2020, MDPI AG

    Thomas Tu

  55. Virus Genotype-Dependent Transcriptional Alterations in Lipid Metabolism and Inflammation Pathways in the Hepatitis C Virus-infected Liver

    Article • Scientific Reports, July 2019, Springer Science + Business Media

    Thomas Tu

  56. Generation and characterization of a stable cell line persistently replicating and secreting the human hepatitis delta virus

    Article • Scientific Reports, July 2019, Springer Science + Business Media

    Thomas Tu

  57. Analyse chromosomal integrierter HBV-DNA durch inverse nested PCR

    Article • BIOspektrum, May 2019, Springer Science + Business Media

    Thomas Tu

  58. Journal Watch: Dr Tu looks back at the most important research articles released in 2018 relating to models and biomarkers of hepatocellular carcinoma

    Article • Hepatic Oncology, March 2019, Future Medicine

    Thomas Tu

  59. Hepatitis B virus (HBV) DNA integration is not driven by viral proteins

    Article • Zeitschrift für Gastroenterologie, January 2019, Thieme Publishing Group

    Thomas Tu

  60. Detection of Low Copy Number Integrated Viral DNA Formed by <em>In Vitro</em> Hepatitis B Infection

    Article • Journal of Visualized Experiments, November 2018, MyJove Corporation

    Thomas Tu

  61. Detection of Low Copy Number Integrated Viral DNA Formed by <em>In Vitro</em> Hepatitis B Infection

    Article • Journal of Visualized Experiments, November 2018, MyJove Corporation

    Thomas Tu

  62. Sequence analysis of integrated hepatitis B virus DNA during HBeAg-seroconversion

    Article • Emerging Microbes & Infections, August 2018, Taylor & Francis

    Thomas Tu

  63. Cellular Genomic Sites of Hepatitis B Virus DNA Integration

    Article • Genes, July 2018, MDPI AG

    Thomas Tu

  64. Virus entry and its inhibition to prevent and treat hepatitis B and hepatitis D virus infections

    Article • Current Opinion in Virology, June 2018, Elsevier

    Thomas Tu

  65. HBV Bypasses the Innate Immune Response and Does Not Protect HCV From Antiviral Activity of Interferon

    Article • Gastroenterology, May 2018, Elsevier

    Ralf Bartenschlager, Thomas Tu

  66. Hepatitis B virus integration into cellular genome

    Article • Journal of Virology, February 2018, ASM Journals

    Thomas Tu

  67. HBV bypasses the innate immune system and does not protect HCV against the antiviral effect of IFN

    Article • Zeitschrift für Gastroenterologie, January 2018, Thieme Publishing Group

    Thomas Tu

  68. HBV DNA Integration: Molecular Mechanisms and Clinical Implications

    Article • Viruses, April 2017, MDPI AG

    Thomas Tu

  69. Chronic viral hepatitis and its association with liver cancer

    Article • Biological Chemistry, January 2017, De Gruyter

    Thomas Tu, Ralf Bartenschlager

  70. Integrated analysis of exosomal microRNA, gene, and pathway regulatory networks in fibrosis and hepatocarcinogenesis

    Article • Journal of Hepatology, January 2017, Elsevier

    Thomas Tu

  71. Viral Hepatitis

    Article • January 2017, Elsevier

    Thomas Tu

  72. Whole genome sequencing analysis of familial primary sclerosing cholangitis

    Article • Journal of Hepatology, January 2017, Elsevier

    Thomas Tu

  73. Detection of Hepatocyte Clones Containing Integrated Hepatitis B Virus DNA Using Inverse Nested PCR

    Article • December 2016, Springer Science + Business Media

    Thomas Tu

  74. Basic Science Liver

    Article • Journal of Gastroenterology and Hepatology, October 2016, Wiley

    Thomas Tu

  75. Accumulation of Deleterious Passenger Mutations Is Associated with the Progression of Hepatocellular Carcinoma

    Article • PLOS One, September 2016, PLOS

    Thomas Tu

  76. Abstracts of the 25th Annual Conference of APASL, February 20–24, 2016, Tokyo, Japan

    Article • Hepatology International, February 2016, Springer Science + Business Media

    Thomas Tu, Mr Nata Pratama Hardjo Lugito

  77. Differential Microrna Expression in Plasma Microvesicles Predict Hepatocellular Carcinoma Regulatory Pathways

    Article • Journal of Hepatology, January 2016, Elsevier

    Thomas Tu

  78. Multi-Omics Landscape of Precancerous Liver Disease

    Article • Journal of Hepatology, January 2016, Elsevier

    Thomas Tu

  79. Hepatocytes in liver injury: Victim, bystander, or accomplice in progressive fibrosis?

    Article • Journal of Gastroenterology and Hepatology, November 2015, Wiley

    Thomas Tu

  80. Analysis of Post-Liver Transplant Hepatitis C Virus Recurrence Using Serial Cluster of Differentiation Antibody Microarrays

    Article • Transplantation, September 2015, Wolters Kluwer Health

    Thomas Tu

  81. Basic Science - Liver

    Article • Journal of Gastroenterology and Hepatology, September 2015, Wiley

    Thomas Tu

  82. P0268 : Accumulation of deleterious passenger mutations during liver injury progression to hepatocellular carcinoma

    Article • Journal of Hepatology, April 2015, Elsevier

    Thomas Tu

  83. Conceptual models for the initiation of hepatitis B virus-associated hepatocellular carcinoma

    Article • Liver International, February 2015, Wiley

    Thomas Tu

  84. Clonal expansion of hepatocytes with a selective advantage occurs during all stages of chronic hepatitis B virus infection

    Article • Journal of Viral Hepatitis, January 2015, Wiley

    Thomas Tu

  85. Our experts highlight the most important research articles across the spectrum of topics relevant to the field of hepatic oncology

    Article • Hepatic Oncology, January 2015, Future Medicine

    Thomas Tu

  86. Poster Presentation Abstracts

    Article • Asia-Pacific Journal of Clinical Oncology, November 2014, Wiley

    Thomas Tu

  87. Hepatocyte Produced Matrix Metalloproteinases Are Regulated by CD147 in Liver Fibrogenesis

    Article • PLOS One, July 2014, PLOS

    Thomas Tu

  88. Novel Aspects of the Liver Microenvironment in Hepatocellular Carcinoma Pathogenesis and Development

    Article • International Journal of Molecular Sciences, May 2014, MDPI AG

    Thomas Tu

  89. Advances in and the future of treatments for hepatitis C

    Article • Expert Review of Gastroenterology & Hepatology, May 2014, Taylor & Francis

    Thomas Tu

  90. Endoscopy Upper

    Article • Journal of Gastroenterology and Hepatology, September 2013, Wiley

    Thomas Tu

  91. “Testing your methyl”: DNA methylation profiling of serum DNA of HCC patients

    Article • Hepatology International, July 2013, Springer Science + Business Media

    Thomas Tu