All Stories

  1. The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2

    Article • Stem Cell Reports, February 2022, Elsevier

    Dr Jochen Bodem

  2. Trim28 acts as restriction factor of prototype foamy virus replication by modulating H3K9me3 marks and destabilizing the viral transactivator Tas

    Article • Retrovirology, December 2021, Springer Science + Business Media

    Dr Jochen Bodem

  3. The Manifold Roles of Sphingolipids in Viral Infections

    Article • Frontiers in Physiology, September 2021, Frontiers

    Dr Jochen Bodem

  4. SARS-CoV-2 Infects Endothelial Cells In Vivo and In Vitro

    Article • Frontiers in Cellular and Infection Microbiology, July 2021, Frontiers

    Dr Jochen Bodem

  5. Facile Synthesis and In Vitro Activity of N-Substituted 1,2-Benzisothiazol-3(2H)-ones against Dengue Virus NS2BNS3 Protease

    Article • Pathogens, April 2021, MDPI AG

    Dr Jochen Bodem

  6. Targeting the Main Protease of SARS‐CoV‐2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors

    Article • Angewandte Chemie International Edition, March 2021, Wiley

    Dr Jochen Bodem

  7. The serotonin reuptake inhibitor Fluoxetine inhibits SARS-CoV-2 in human lung tissue

    Article • Scientific Reports, March 2021, Springer Science + Business Media

    Dr Jochen Bodem

  8. Towards a broad-spectrum antiviral, the myristoyltransferase inhibitor IMP-1088 suppresses viral replication – the Yellow fever NS5 is myristoylated

    Article • March 2021, Cold Spring Harbor Laboratory Press

    Dr Jochen Bodem

  9. The SARS-CoV-2 RNA–protein interactome in infected human cells

    Article • Nature Microbiology, December 2020, Springer Science + Business Media

    Dr Jochen Bodem

  10. A direct RNA-protein interaction atlas of the SARS-CoV-2 RNA in infected human cells

    Article • July 2020, Cold Spring Harbor Laboratory Press

    Dr Jochen Bodem

  11. The serotonin reuptake inhibitor Fluoxetine inhibits SARS-CoV-2

    Article • June 2020, Cold Spring Harbor Laboratory Press

    Dr Jochen Bodem

  12. Exon-4 Mutations in KRAS Affect MEK/ERK and PI3K/AKT Signaling in Human Multiple Myeloma Cell Lines

    Article • Cancers, February 2020, MDPI AG

    Dr Jochen Bodem

  13. Proline-Based Allosteric Inhibitors of Zika and Dengue Virus NS2B/NS3 Proteases

    Article • Journal of Medicinal Chemistry, November 2019, American Chemical Society (ACS)

    Dr Jochen Bodem

  14. Corrigendum to “Spumaretroviruses: Updated taxonomy and nomenclature” [Virology 516 (2018) 158–164]

    Article • Virology, February 2019, Elsevier

    Dr Jochen Bodem, Dr Jens H. Kuhn

  15. Spumaretroviruses: Updated taxonomy and nomenclature

    Article • Virology, March 2018, Elsevier

    Dr Jochen Bodem, Dr Jens H. Kuhn

  16. Low doses of cholera toxin and its mediator cAMP induce CTLA-2 secretion by dendritic cells to enhance regulatory T cell conversion

    Article • PLoS ONE, July 2017, PLOS

    Dr Jochen Bodem

  17. Purification of foamy viral particles

    Article • Virology, June 2017, Elsevier

    Dr Jochen Bodem

  18. A purine-rich element in foamy virus pol regulates env splicing and gag/pol expression

    Article • Retrovirology, February 2017, Springer Science + Business Media

    Dr Jochen Bodem

  19. Sequence errors in foamy virus sequences in the GenBank database: resequencing of the prototypic foamy virus proviral plasmids

    Article • Archives of Virology, December 2016, Springer Science + Business Media

    Dr Jochen Bodem

  20. Flavonoids as noncompetitive inhibitors of Dengue virus NS2B-NS3 protease: Inhibition kinetics and docking studies

    Article • Bioorganic & Medicinal Chemistry, February 2015, Elsevier

    Dr Jochen Bodem

  21. Novel Dengue Virus NS2B/NS3 Protease Inhibitors

    Article • Antimicrobial Agents and Chemotherapy, December 2014, ASM Journals

    Dr Jochen Bodem, Ralf Bartenschlager

  22. Obituary: Axel Rethwilm (1959–2014)

    Article • Retrovirology, September 2014, Springer Science + Business Media

    Dr Jochen Bodem

  23. Determination of the protease cleavage site repertoire—The RNase H but not the RT domain is essential for foamy viral protease activity

    Article • Virology, April 2014, Elsevier

    Dr Jochen Bodem

  24. Evolution of Foamy Viruses: The Most Ancient of All Retroviruses

    Article • Viruses, September 2013, MDPI AG

    Dr Jochen Bodem

  25. Foamy Virus Gag p71-p68 Cleavage Is Required for Template Switch of the Reverse Transcriptase

    Article • Journal of Virology, April 2013, ASM Journals

    Dr Jochen Bodem

  26. Regulation of Retroviral Polyadenylation

    Article • January 2013, Elsevier

    Dr Jochen Bodem

  27. U1snRNP-mediated suppression of polyadenylation in conjunction with the RNA structure controls poly (A) site selection in foamy viruses

    Article • Retrovirology, January 2013, Springer Science + Business Media

    Dr Jochen Bodem, Dr Jens Bohne, Professor Birgitta M Wöhrl

  28. Construction of a High Titer Infectious HIV-1 Subtype C Proviral Clone from South Africa

    Article • Viruses, September 2012, MDPI AG

    Dr Jochen Bodem

  29. A complex immunodeficiency is based on U1 snRNP-mediated poly(A) site suppression

    Article • The EMBO Journal, September 2012, Wiley

    Dr Jochen Bodem, Dr Jens Bohne

  30. Mutations in HIV-1gagandpolCompensate for the Loss of Viral Fitness Caused by a Highly Mutated Protease

    Article • Antimicrobial Agents and Chemotherapy, May 2012, ASM Journals

    Viktor Müller, Dr Jochen Bodem

  31. The prototype foamy virus protease is active independently of the integrase domain

    Article • Retrovirology, January 2012, Springer Science + Business Media

    Dr Jochen Bodem

  32. HIV Drug Resistance (HIVDR) in Antiretroviral Therapy-Naïve Patients in Tanzania Not Eligible for WHO Threshold HIVDR Survey Is Dramatically High

    Article • PLoS ONE, August 2011, PLOS

    Dr Jochen Bodem

  33. Regulation of Foamy Virus Protease Activity by Viral RNA: a Novel and Unique Mechanism among Retroviruses

    Article • Journal of Virology, February 2011, ASM Journals

    Dr Jochen Bodem

  34. Basic Residues in the Foamy Virus Gag Protein

    Article • Journal of Virology, February 2011, ASM Journals

    Dr Jochen Bodem

  35. Regulation of Foamy Viral Transcription and RNA Export

    Article • January 2011, Elsevier

    Dr Jochen Bodem

  36. Regulation of foamy virus protease activity by viral RNA

    Article • Retrovirology, January 2011, Springer Science + Business Media

    Dr Jochen Bodem

  37. Foamy Virus Nuclear RNA Export Is Distinct from That of Other Retroviruses

    Article • Journal of Virology, December 2010, ASM Journals

    Dr Jochen Bodem

  38. Complete nucleotide sequence and evolutionary analysis of a Gorilla foamy virus

    Article • Journal of General Virology, November 2010, Society for General Microbiology

    Dr Jochen Bodem

  39. Formation of transient dimers by a retroviral protease

    Article • Biochemical Journal, April 2010, Portland Press Ltd.

    Dr Jochen Bodem

  40. Molecular Analysis of HIV Type 1 vif Sequences from Cape Town, South Africa

    Article • AIDS Research and Human Retroviruses, July 2008, Mary Ann Liebert Inc

    Dr Jochen Bodem

  41. Phylogenetic Diversity and Low Level Antiretroviral Resistance Mutations in HIV Type 1 Treatment-Naive Patients from Cape Town, South Africa

    Article • AIDS Research and Human Retroviruses, July 2008, Mary Ann Liebert Inc

    Dr Jochen Bodem

  42. Characterisation of a chikungunya virus from a German patient returning from Mauritius and development of a serological test

    Article • Medical Microbiology and Immunology, March 2008, Springer Science + Business Media

    Dr Jochen Bodem

  43. Genotypic resistance testing in HIV by arrayed primer extension

    Article • Analytical and Bioanalytical Chemistry, January 2008, Springer Science + Business Media

    Dr Jochen Bodem, Dr Kurt Fellenberg

  44. The complete nucleotide sequence of a New World simian foamy virus

    Article • Virology, December 2007, Elsevier

    Dr Jochen Bodem

  45. Acetylation of the foamy virus transactivator Tas by PCAF augments promoter-binding affinity and virus transcription

    Article • Journal of General Virology, January 2007, Society for General Microbiology

    Dr Jochen Bodem

  46. From nonpeptide toward noncarbon protease inhibitors: Metallacarboranes as specific and potent inhibitors of HIV protease

    Article • Proceedings of the National Academy of Sciences, October 2005, Proceedings of the National Academy of Sciences

    Dr Jochen Bodem

  47. A peptide inhibitor of HIV-1 assembly in vitro

    Article • Nature Structural & Molecular Biology, July 2005, Springer Science + Business Media

    Dr Jochen Bodem

  48. Comparative functional characterization of the feline foamy virus transactivator reveals its species specificity

    Article • Virology, January 2004, Elsevier

    Dr Jochen Bodem

  49. The Mason-Pfizer Monkey Virus PPPY and PSAP Motifs Both Contribute to Virus Release

    Article • Journal of Virology, September 2003, ASM Journals

    Dr Jochen Bodem

  50. Identification of protein phosphorylation sites by combination of elastase digestion, immobilized metal affinity chromatography, and quadrupole-time of flight tandem mass spectrometry

    Article • PROTEOMICS, July 2002, Wiley

    Dr Jochen Bodem

  51. Modification of Immobilized Peptides

    Article • January 2002, Springer Science + Business Media

    Dr Jochen Bodem

  52. TIF-IA, the factor mediating growth-dependent control of ribosomal RNA synthesis, is the mammalian homolog of yeast Rrn3p

    Article • EMBO Reports, August 2000, EMBO

    Dr Jochen Bodem

  53. Construction of Infectious Feline Foamy Virus Genomes: Cat Antisera Do Not Cross-Neutralize Feline Foamy Virus Chimera with Serotype-Specific Env Sequences

    Article • Virology, January 2000, Elsevier

    Dr Jochen Bodem

  54. Nuclear Localization of the Functional Bel 1 Transactivator but Not of the Gag Proteins of the Feline Foamy Virus

    Article • Virology, November 1998, Elsevier

    Dr Jochen Bodem

  55. Detection of Subgenomic cDNAs and Mapping of Feline Foamy Virus mRNAs Reveals Complex Patterns of Transcription

    Article • Virology, May 1998, Elsevier

    Dr Jochen Bodem

  56. A rapid streptavidin-capture ELISA specific for the detection of antibodies to feline foamy virus

    Article • Journal of Immunological Methods, August 1997, Elsevier

    Dr Jochen Bodem

  57. Regulation of gene expression by human foamy virus and potentials of foamy viral vectors

    Article • Stem Cells, April 1997, Wiley

    Dr Jochen Bodem