All Stories

  1. Bacterial Cofactors for CRISPR Activation

    Article • Biochemistry, February 2026, American Chemical Society (ACS)

    Quanjiang Ji

  2. Protocol for Discovery and Characterization of Miniature Cas12 Systems

    Article • ACS Chemical Biology, February 2026, American Chemical Society (ACS)

    Quanjiang Ji

  3. Phage-associated Cas12p nucleases require binding to bacterial thioredoxin for activation and cleavage of target DNA

    Article • Nature Microbiology, January 2026, Springer Science + Business Media

    Quanjiang Ji

  4. Mechanisms and engineering of a miniature type V-N CRISPR-Cas12 effector enzyme

    Article • Nature Communications, July 2025, Springer Science + Business Media

    Quanjiang Ji

  5. Systematic trans‐Activity Comparison of Several Reported Cas12f Nucleases†

    Article • Chinese Journal of Chemistry, March 2025, Wiley

    Quanjiang Ji, Quanjiang Ji

  6. Prime editing in bacteria with BacPE

    Article • January 2025, Elsevier

    Quanjiang Ji

  7. Characterization and Engineering of a Novel Miniature Eubacterium siraeum CRISPR-Cas12f System

    Article • ACS Synthetic Biology, June 2024, American Chemical Society (ACS)

    Quanjiang Ji, Quanjiang Ji

  8. Miniature CRISPR-Cas12 Systems: Mechanisms, Engineering, and Genome Editing Applications

    Article • ACS Chemical Biology, June 2024, American Chemical Society (ACS)

    Quanjiang Ji, Quanjiang Ji

  9. BacPE: a versatile prime-editing platform in bacteria by inhibiting DNA exonucleases

    Article • Nature Communications, January 2024, Springer Science + Business Media

    Quanjiang Ji, Quanjiang Ji

  10. A KDPG sensor RccR governs Pseudomonas aeruginosa carbon metabolism and aminoglycoside antibiotic tolerance

    Article • Nucleic Acids Research, December 2023, Oxford University Press (OUP)

    Quanjiang Ji, Quanjiang Ji

  11. Molecular Basis and Genome Editing Applications of a Compact Eubacterium ventriosum CRISPR-Cas9 System

    Article • ACS Synthetic Biology, December 2023, American Chemical Society (ACS)

    Quanjiang Ji, Quanjiang Ji

  12. CRISPR/Cas9-based Genome Editing of Pseudomonas aeruginosa

    Article • October 2023, Springer Science + Business Media

    Quanjiang Ji

  13. Molecular basis and engineering of miniature Cas12f with C-rich PAM specificity

    Article • Nature Chemical Biology, September 2023, Springer Science + Business Media

    Quanjiang Ji, Quanjiang Ji

  14. Structure and engineering of miniature Acidibacillus sulfuroxidans Cas12f1

    Article • Nature Catalysis, July 2023, Springer Science + Business Media

    Quanjiang Ji, Quanjiang Ji

  15. Cas12n nucleases, early evolutionary intermediates of type V CRISPR, comprise a distinct family of miniature genome editors

    Article • Molecular Cell, July 2023, Elsevier

    Quanjiang Ji, Quanjiang Ji

  16. Identification of Editable Sites, Spacer Oligonucleotide Design, and Generation of the Gene-Targeting CRISPR–nCas9 Plasmid for Gene Disruption inStaphylococcus aureusUsing the CRISPR–nCas9 and Cytidine Deaminase System

    Article • Cold Spring Harbor Protocols, April 2023, Cold Spring Harbor Laboratory Press

    Quanjiang Ji

  17. Introduction of a CRISPR–nCas9 Gene-Targeting Plasmid intoStaphylococcus aureusfor Gene Disruption

    Article • Cold Spring Harbor Protocols, April 2023, Cold Spring Harbor Laboratory Press

    Quanjiang Ji

  18. Using CRISPR–Cas9-Based Methods for Genome Editing inStaphylococcus aureus

    Article • Cold Spring Harbor Protocols, April 2023, Cold Spring Harbor Laboratory Press

    Quanjiang Ji

  19. Guide RNA engineering enables efficient CRISPR editing with a miniature Syntrophomonas palmitatica Cas12f1 nuclease

    Article • Cell Reports, September 2022, Elsevier

    Quanjiang Ji, Quanjiang Ji

  20. CRISPR/Cpf1-Mediated Multiplex and Large-Fragment Gene Editing in Staphylococcus aureus

    Article • ACS Synthetic Biology, August 2022, American Chemical Society (ACS)

    Quanjiang Ji, Quanjiang Ji

  21. Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli

    Article • Nucleic Acids Research, May 2022, Oxford University Press (OUP)

    Quanjiang Ji, Quanjiang Ji, Dr. Shuyu Zhang

  22. Genome Editing in Klebsiella pneumoniae Using CRISPR/Cas9 Technology

    Article • January 2022, Springer Science + Business Media

    Quanjiang Ji, Quanjiang Ji

  23. Programmed genome editing by a miniature CRISPR-Cas12f nuclease

    Article • Nature Chemical Biology, September 2021, Springer Science + Business Media

    Quanjiang Ji, Quanjiang Ji

  24. Targeted genetic screening in bacteria with a Cas12k-guided transposase

    Article • Cell Reports, August 2021, Elsevier

    Quanjiang Ji, Quanjiang Ji

  25. CRISPR-CBEI: a Designing and Analyzing Tool Kit for Cytosine Base Editor-Mediated Gene Inactivation

    Article • mSystems, September 2020, ASM Journals

    Quanjiang Ji, Quanjiang Ji

  26. Catalytic-state structure and engineering of Streptococcus thermophilus Cas9

    Article • Nature Catalysis, September 2020, Springer Science + Business Media

    Quanjiang Ji, Quanjiang Ji

  27. CRISPR-Cas9-Based Genome Editing and Cytidine Base Editing in Acinetobacter baumannii

    Article • STAR Protocols, June 2020, Elsevier

    Quanjiang Ji, Quanjiang Ji

  28. Structural Basis of Staphylococcus aureus Surface Protein SdrC

    Article • Biochemistry, April 2020, American Chemical Society (ACS)

    Quanjiang Ji, Quanjiang Ji

  29. Programmable adenine deamination in bacteria using a Cas9–adenine-deaminase fusion

    Article • Chemical Science, January 2020, Royal Society of Chemistry

    Quanjiang Ji, Quanjiang Ji

  30. Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease

    Article • PLoS Biology, October 2019, PLOS

    Quanjiang Ji, Quanjiang Ji

  31. Genetic Manipulation of MRSA Using CRISPR/Cas9 Technology

    Article • September 2019, Springer Science + Business Media

    Quanjiang Ji, Quanjiang Ji

  32. A Highly Efficient CRISPR-Cas9-Based Genome Engineering Platform in Acinetobacter baumannii to Understand the H2O2-Sensing Mechanism of OxyR

    Article • Cell Chemical Biology, September 2019, Elsevier

    Quanjiang Ji, Quanjiang Ji

  33. Application of CRISPR/Cas9-Based Genome Editing in Studying the Mechanism of Pandrug Resistance in Klebsiella pneumoniae

    Article • Antimicrobial Agents and Chemotherapy, April 2019, ASM Journals

    Quanjiang Ji, Quanjiang Ji

  34. Genome editing in Klebsiella pneumoniae using CRISPR-Cas9 and CRISPR-assisted cytidine deaminase

    Article • Applied and Environmental Microbiology, September 2018, ASM Journals

    Quanjiang Ji, Quanjiang Ji

  35. CRISPR-based genome editing in Pseudomonas species

    Article • iScience, August 2018, Elsevier

    Quanjiang Ji, Quanjiang Ji

  36. Molecular mechanism of staphylopine-mediated metal acquisition

    Article • Proceedings of the National Academy of Sciences, March 2018, Proceedings of the National Academy of Sciences

    Quanjiang Ji, Dr. Shuyu Zhang, Quanjiang Ji

  37. Cytidine deaminase-mediated base editing in Staphylococcus aureus

    Article • Chemical Science, January 2018, Royal Society of Chemistry

    Quanjiang Ji, Quanjiang Ji

  38. One-step genome editing of Staphylococcus aureus by CRISPR/Cas9

    Article • Journal of the American Chemical Society, March 2017, American Chemical Society (ACS)

    Quanjiang Ji, Quanjiang Ji