What is it about?
CRISPR-Cas9 and cytidine deaminase mediated genome editing tools enabled highly efficient gene deletion and inactivation in both the chromosomal and plasmid-borne genes.
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Why is it important?
The methods will facilitate physiology studies in Klebsiella pneumoniae, including drug resistance and pathogenesis.
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This page is a summary of: CRISPR-Cas9 and CRISPR-Assisted Cytidine Deaminase Enable Precise and Efficient Genome Editing in Klebsiella pneumoniae, Applied and Environmental Microbiology, September 2018, ASM Journals,
DOI: 10.1128/aem.01834-18.
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