All Stories

  1. A Synthetic Approach to Diverse Indole/Oxindole-Annulated S -Heterocycles
  2. Construction and Asymmetric Skeletal Rearrangement of Medium-Sized Rings: Divergent Synthesis of Pyrazole/Pyrazolone-Annulated Frameworks
  3. Indocyanine polymethine fluorophores with extended π-conjugation emitting beyond 1,200 nm for enhanced NIR-II imaging
  4. Organocatalytic asymmetric tandem reaction for the enantioselective synthesis of chiral oxindoles to construct CyK dyes
  5. Allylic C–H oxygenation of unactivated internal olefins by the Cu/azodiformate catalyst system
  6. NCI-driven regioselectivity and enantioreversal in chiral phosphoric acid-catalyzed arylamine functionalization
  7. One-pot cobalt-catalyzed ring-opening of diaziridines for bismuth-promoted Fischer indole synthesis
  8. Stepwise or Concerted Mechanisms? Rethinking of the Classical Carbocation Rearrangement Reaction
  9. Organocatalytic Asymmetric Synthesis of Sulfonyl-Substituted Furans via a Cascade 1,6-Addition/Cyclization/Enantioselective Protonation Pathway
  10. Enantioselective sequential Michael addition/C-H olefination/Michael reaction for the efficient collective synthesis of clavine alkaloids
  11. Asymmetric Intramolecular Amination Catalyzed with Cp*Ir-SPDO via Nitrene Transfer for Synthesis of Spiro-Quaternary Indolinone
  12. Regioselective Electrooxidative [3+2] Annulation between Indole and Aniline Derivatives to Construct Functionalized Indolo[2,3-b]indoles
  13. Atroposelective synthesis of biaxial bridged eight-membered terphenyls via a Co/SPDO-catalyzed aerobic oxidative coupling/desymmetrization of phenols
  14. Enantioselective Synthesis of Axially Chiral Sulfone-Containing Styrenes Based on Ion-Exchange Strategy
  15. How achiral Brønsted acid is involved in co-catalyst model with chiral phosphoric acid for construction of quaternary carbon stereocenter
  16. Cooperative Cu/azodiformate system-catalyzed allylic C–H amination of unactivated internal alkenes directed by aminoquinoline
  17. Colorless transparent and thermally stable terphenyl polyimides with various small side groups for substrate application
  18. Bringing Green Organic Electrochemistry to Undergraduates: A Designed Comparison Organic Experiment of Bromination
  19. An Axially Chiral Styrene–Phosphine Ligand for Pd-Catalyzed Asymmetric N-Alkylation of Indoles
  20. Stereoselective Sulfa-Michael/Aldol Reaction Promoted by an Axially Chiral Styrene-Based Organocatalyst
  21. Total Syntheses of Polycyclic Diterpenes Phomopsene, Methyl Phomopsenonate, and iso-Phomopsene via Reorganization of C–C Single Bonds
  22. Asymmetric Intramolecular Hydroalkylation of Internal Olefin with Cycloalkanone to Directly Access Polycyclic Systems
  23. Asymmetric Intramolecular Hydroalkylation of Internal Olefin with Cycloalkanone to Directly Access Polycyclic Systems
  24. Synthetic strategies and mechanistic studies of axially chiral styrenes
  25. Electroreductive fluoroalkylative heteroarylation of unactivated alkenes via an unconventional remote heteroaryl migration
  26. Project-Based Learning in Green Electrochemistry for Undergraduates: An Efficient Synthesis Route of a Natural Product
  27. Axially chiral styrene-based organocatalysts and their application in asymmetric cascade Michael/cyclization reaction
  28. Bioinspired Palladium‐Catalyzed Intramolecular C(sp3)−H Activation for the Collective Synthesis of Proline Natural Products
  29. Bioinspired Palladium‐Catalyzed Intramolecular C(sp3)−H Activation for the Collective Synthesis of Proline Natural Products
  30. Chiral Phosphoric Acid-Catalyzed Enantioselective Dearomative Electrophilic Hydrazination: Access to Chiral Aza-Quaternary Carbon Indolenines
  31. Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli
  32. Highly Site‐ and Enantioselective N—H Functionalization of N‐Monosubstituted Aniline Derivatives Affording Pyrazolones Bearing a Quaternary Stereocenter
  33. Bromine and oxygen redox species mediated highly selective electro-epoxidation of styrene
  34. Electrochemical collective synthesis of labeled pyrroloindoline alkaloids with Freon-type methanes as functional C1 synthons
  35. Terphenyl-based colorless and heat-resistant polyimides with a controlled molecular structure using methyl side groups
  36. Base-Promoted Cobalt-Catalyzed Regio- and Enantioselective para-Friedel–Crafts Alkylation of Aniline Derivatives
  37. Organocatalytic Direct Asymmetric Indolization from Anilines by Enantioselective [3 + 2] Annulation
  38. Paired Electrolysis Enabled Ni-Catalyzed Unconventional Cascade Reductive Thiolation Using Sulfinates
  39. Using Computational Chemistry to Improve Students’ Multidimensional Understanding of Complex Electrophilic Aromatic Substitution Reactions: Further Analysis of the Solvent Effect, Temperature Influence, and Kinetic Behaviors
  40. Correction to “Highly Chemo-, Site-, and Enantioseletive para C–H Aminoalkylation of N-Monosubstituted Aniline Derivatives Affording 3-Amino-2-Oxindoles”
  41. Co-Catalyzed Direct Regio- and Enantioselective Intermolecular γ-Amination of N-Acylpyrazoles
  42. Fe-Catalyzed Sequential C(sp3)–H/N–H Annulation of 2-Methylindoles with Ethyl Trifluoropyruvate at Room Temperature: Construction of Pyrrolo[1,2-α]indoles
  43. Total Synthesis of Fawcettimine-Type Alkaloid, Lycojaponicumin A
  44. Highly Chemo-, Site-, and Enantioseletive para C–H Aminoalkylation of N-Monosubstituted Aniline Derivatives Affording 3-Amino-2-oxindoles
  45. Organocatalytic Enantioselective Construction of Heterocycle-Substituted Styrenes with Chiral Atropisomerism
  46. A dienamine-mediated deconjugative addition/cyclization cascade of γ,γ-disubstituted enals with carboxylic acid-activated enones: a rapid access to highly functionalized γ-lactones
  47. Remote C6-Enantioselective C–H Functionalization of 2,3-Disubstituted Indoles through the Dual H-Bonds and π–π Interaction Strategy Enabled by CPAs
  48. Cobalt-Catalyzed Ortho-C(sp2)–H Amidation of Benzaldehydes with Dioxazolones Using Transient Directing Groups
  49. Lewis Base/Brønsted Acid Co-catalyzed Enantioselective Sulfenylation/Semipinacol Rearrangement of Di- and Trisubstituted Allylic Alcohols
  50. Highly atroposelective synthesis of nonbiaryl naphthalene-1,2-diamine N-C atropisomers through direct enantioselective C-H amination
  51. Copper-Complex-Catalyzed Asymmetric Aerobic Oxidative Cross-Coupling of 2-Naphthols: Enantioselective Synthesis of 3,3′-Substituted C1 -Symmetric BINOLs
  52. Design and synthesis of a novel quinoxaline diamine and its polyimides with high-Tg and red color
  53. Silver-Catalyzed para-Selective C–H Amination of 1-Naphthyl­amides with Azodicarboxylates at Room Temperature
  54. Asymmetric N-Hydroxyalkylation of Indoles with Ethyl Glyoxalates Catalyzed by a Chiral Phosphoric Acid: Highly Enantioselective Synthesis of Chiral N,O-Aminal Indole Derivatives
  55. Electrochemical Semipinacol Rearrangements of Allylic Alcohols: Construction of All-Carbon Quaternary Stereocenters
  56. Dual Directing-Groups-Assisted Redox-Neutral Annulation and Ring Opening of N-Aryloxyacetamides with 1-Alkynylcyclobutanols via Rhodium(III)-Catalyzed C–H/C–C Activations
  57. Asymmetric Organocatalytic Synthesis of 2,3-Allenamides from Hydrogen-Bond-Stabilized Enynamides
  58. Computational and experimental studies on copper-mediated selective cascade C–H/N–H annulation of electron-deficient acrylamide with arynes
  59. Electrochemical halogenation/semi-pinacol rearrangement of allylic alcohols using inorganic halide salt: an eco-friendly route to the synthesis of β-halocarbonyls
  60. Synthesis, structures, and thermodynamics/kinetics properties of three Zn(II) coordination polymers modified by 5-substituted isophthalic acid
  61. Rhodium(III)-Catalyzed Redox-Neutral Cascade [3 + 2] Annulation of N-Phenoxyacetamides with Propiolates via C–H Functionalization/Isomerization/Lactonization
  62. Asymmetric intramolecular Friedel–Crafts reaction catalyzed by a spiropyrrolidine organocatalyst: Enantioselective construction of indolizine and azepine frameworks
  63. Transition Metal-Controlled Direct Regioselective Intermolecular Amidation of C−H Bonds with Azodicarboxylates: Scope, Mechanistic Studies, and Applications
  64. A Facile Approach to Oximes and Ethers by a Tandem NO + ‐Initiated Semipinacol Rearrangement and H‐Elimination
  65. A Facile Approach to Oximes and Ethers by a Tandem NO+ -Initiated Semipinacol Rearrangement and H-Elimination
  66. Electrophilic Trifluoromethylthiolation/Semipinacol Rearrangement: Preparation of β-SCF3 Carbonyl Compounds with α-Quaternary Carbon Center
  67. Metal-Controlled, Regioselective, Direct Intermolecular α- or γ-Amination with Azodicarboxylates
  68. Molecular mechanism of staphylopine-mediated metal acquisition
  69. Experimental and computational studies on H2O-promoted, Rh-catalyzed transient-ligand-free ortho-C(sp2)–H amidation of benzaldehydes with dioxazolones
  70. Recent progress in the isolation, bioactivity, biosynthesis, and total synthesis of natural spiroketals
  71. Copper-Mediated Cascade C–H/N–H Annulation of Indolocarboxamides with Arynes: Construction of Tetracyclic Indoloquinoline Alkaloids
  72. Catalytic Asymmetric Cascade Using Spiro-Pyrrolidine Organocatalyst: Efficient Construction of Hydrophenanthridine Derivatives
  73. Stereoselective Synthesis of Z-Vinylsilanes via Palladium-Catalyzed Direct Intermolecular Silylation of C(sp2)–H Bonds
  74. Copper-Catalyzed Selective ortho-C–H/N–H Annulation of Benzamides with Arynes: Synthesis of Phenanthridinone Alkaloids
  75. Palladium-Catalyzed Direct Intermolecular Amination of Unactivated Methylene C(sp3)–H Bonds with Azodiformates via Bidentate-Chelation Assistance
  76. Palladium-catalyzed direct intermolecular silylation of remote unactivated C(sp3)–H bonds
  77. Tandem C–H oxidation/cyclization/rearrangement and its application to asymmetric syntheses of (−)-brussonol and (−)-przewalskine E
  78. Gold(I)/Copper(II)-Cocatalyzed Tandem Cyclization/Semipinacol Reaction: Construction of 6-Aza/Oxa-Spiro[4.5]decane Skeletons and Formal Synthesis of (±)-Halichlorine
  79. Palladium-catalyzed alkylation of unactivated C(sp3)–H bonds with primary alkyl iodides at room temperature: facile synthesis of β-alkyl α-amino acids
  80. Pd-Catalyzed Monoselective ortho-C–H Alkylation of N-Quinolyl Benzamides: Evidence for Stereoretentive Coupling of Secondary Alkyl Iodides
  81. Total Synthesis of Hibispeptin A via Pd-Catalyzed C(sp3)–H Arylation with Sterically Hindered Aryl Iodides
  82. Palladium-Catalyzed Stereoretentive Olefination of Unactivated C(sp3)–H Bonds with Vinyl Iodides at Room Temperature: Synthesis of β-Vinyl α-Amino Acids
  83. Palladium-catalyzed picolinamide-directed halogenation of ortho C–H bonds of benzylamine substrates
  84. Palladium-catalyzed trifluoroacetate-promoted mono-arylation of the β-methyl group of alanine at room temperature: synthesis of β-arylated α-amino acids through sequential C–H functionalization
  85. Palladium-Catalyzed Picolinamide-Directed Acetoxylation of Unactivated γ-C(sp3)H Bonds of Alkylamines
  86. Copper-Catalyzed Carboxamide-Directed Ortho Amination of Anilines with Alkylamines at Room Temperature
  87. A Synthetic Approach for Constructing the 3/6/6/5-Fused Tetracyclic Skeleton of Tenuipesine A
  88. Toward the natural didemnaketal A: total synthesis of the isomer of didemnaketal A
  89. Use of a Readily Removable Auxiliary Group for the Synthesis of Pyrrolidones by the Palladium-Catalyzed Intramolecular Amination of Unactivated γ C(sp3)H Bonds
  90. Stereoselective Synthesis of β-Alkylated α-Amino Acids via Palladium-Catalyzed Alkylation of Unactivated Methylene C(sp3)–H Bonds with Primary Alkyl Halides
  91. Iodination of Remote Ortho-C–H Bonds of Arenes via Directed SEAr: A Streamlined Synthesis of Tetrahydroquinolines
  92. Synthesis of phenanthridines via palladium-catalyzed picolinamide-directed sequential C–H functionalization
  93. Direct Syntheses of Spiro- and Fused-Hydrofurans by a Tunable Tandem Semipinacol Rearrangement/Oxa-Michael Addition Protocol
  94. Cascade Oxidative Dearomatization/Semipinacol Rearrangement: An Approach to 2-Spirocyclo-3-oxindole Derivatives
  95. Palladium-Catalyzed Picolinamide-Directed Alkylation of Unactivated C(sp3)–H Bonds with Alkyl Iodides
  96. Tandem Semipinacol-Type 1,2-Carbon Migration/Aldol Reaction toward the Construction of [5–6–7] All-Carbon Tricyclic Core of Calyciphylline A-Type Alkaloids
  97. Organocatalytic Asymmetric Direct C sp 3H Functionalization of Ethers: A Highly Efficient Approach to Chiral Spiroethers
  98. Efficient Alkyl Ether Synthesis via Palladium-Catalyzed, Picolinamide-Directed Alkoxylation of Unactivated C(sp3)–H and C(sp2)–H Bonds at Remote Positions
  99. Formal Synthesis of (−)-Cephalotaxine Based on a Tandem Hydroamination/Semipinacol Rearrangement Reaction
  100. Studies on the Total Synthesis of 8-epi-Liphagal
  101. Highly Efficient Syntheses of Azetidines, Pyrrolidines, and Indolines via Palladium Catalyzed Intramolecular Amination of C(sp3)–H and C(sp2)–H Bonds at γ and δ Positions
  102. Selective fluorescent probes for live-cell monitoring of sulphide
  103. Chiral Brønsted Acid-Promoted Enantioselective Desymmetrization in an Intramolecular Schmidt Reaction of Symmetric Azido 1,3-Hexanediones: Asymmetric Synthesis of Azaquaternary Pyrroloazepine Skeletons
  104. Development of the Intramolecular Prins Cyclization/Schmidt Reaction for the Construction of the Azaspiro[4,4]nonane: Application to the Formal Synthesis of (±)-Stemonamine
  105. Direct Sp3α-C–H activation and functionalization of alcohol and ether
  106. Iron-Catalyzed C(sp3)C(sp3) Bond Formation through C(sp3)H Functionalization: A Cross-Coupling Reaction of Alcohols with Alkenes
  107. A RhCl(PPh3)3/BF3·OEt2 co-promoted direct C–C cross-coupling of alcohols at β-position with aldehydes
  108. Cross-Coupling Reaction between Alcohols through sp3CH Activation Catalyzed by a Ruthenium/Lewis Acid System
  109. Tandem Aziridination/Rearrangement Reaction of Allylic Alcohols: An Efficient Approach to 2-Quaternary Mannich Bases
  110. Prolinamide/PPTS-Catalyzed Hajos-Parrish Annulation: Efficient Approach to the Tricyclic Core of Cylindricine-Type Alkaloids
  111. A Direct CC Cross-Coupling of Alcohols at the β-Position with Aldehydes under Co-Promotion of Tris(triphenylphosphine)rhodium Chloride/Boron Trifuoride Etherate
  112. A coupling reaction between tetrahydrofuran and olefins by Rh-catalyzed/Lewis acid-promoted C–H activation
  113. Palladium-Catalyzed/Lewis Acid-Promoted Alkene Dimerization and Cross-Coupling with AlcoholsviaCH Bond Activation
  114. Asymmetric Synthesis of the C(17)–C(28)Subunit of Didemnaketal B
  115. An alternative synthetic approach towards erythrinan and homoerythrinan alkaloids by tandem semipinacol/intramolecular Schmidt reaction
  116. General and Efficient Strategy for Erythrinan and Homoerythrinan Alkaloids:  Syntheses of (±)-3-Demethoxyerythratidinone and (±)-Erysotramidine
  117. Quinine/selectfluor combination induced asymmetric semipinacol rearrangement of allylic alcohols: an effective and enantioselective approach to α-quaternary β-fluoro aldehydes
  118. An Efficient Total Synthesis of (±)-Lycoramine
  119. A General Efficient Strategy forcis-3a-Aryloctahydroindole Alkaloids via Stereocontrolled ZnBr2-Catalyzed Rearrangement of 2,3-Aziridino Alcohols