All Stories

  1. Photothermal catalysis versus thermal catalysis: A palladium-catalyzed intermolecular three-component C─H 1,3- N , O -difunctionalization
  2. Axially Chiral Styrene-Based Organocatalysts: Structure–Activity Relationship, Density Functional Theory Calculations and Application
  3. Styrene-Based Axial Chiral Catalyst-Catalyzed Asymmetric Synthesis of Spirobarbiturates through Chiral Proton Shuttle
  4. Ligand-Relay Strategy Enabling Copper-Catalyzed C–C/C–O/C–N Cascade Trifunctionalization of Internal Alkynes and Propargylic Sites: Synthesis of Benzofuran-β-Lactams
  5. Circularly Polarized Luminescence with Large Dissymmetry Factor over 10 −1 Based on Flexible Point‐Chirality via Programming at Molecular Level
  6. Circularly Polarized Luminescence with Large Dissymmetry Factor over 10 −1 Based on Flexible Point‐Chirality via Programming at Molecular Level
  7. A Synthetic Approach to Diverse Indole/Oxindole-Annulated S -Heterocycles
  8. Construction and Asymmetric Skeletal Rearrangement of Medium-Sized Rings: Divergent Synthesis of Pyrazole/Pyrazolone-Annulated Frameworks
  9. Indocyanine polymethine fluorophores with extended π-conjugation emitting beyond 1,200 nm for enhanced NIR-II imaging
  10. Organocatalytic asymmetric tandem reaction for the enantioselective synthesis of chiral oxindoles to construct CyK dyes
  11. Allylic C–H oxygenation of unactivated internal olefins by the Cu/azodiformate catalyst system
  12. NCI-driven regioselectivity and enantioreversal in chiral phosphoric acid-catalyzed arylamine functionalization
  13. One-pot cobalt-catalyzed ring-opening of diaziridines for bismuth-promoted Fischer indole synthesis
  14. Stepwise or Concerted Mechanisms? Rethinking of the Classical Carbocation Rearrangement Reaction
  15. Organocatalytic Asymmetric Synthesis of Sulfonyl-Substituted Furans via a Cascade 1,6-Addition/Cyclization/Enantioselective Protonation Pathway
  16. Enantioselective sequential Michael addition/C-H olefination/Michael reaction for the efficient collective synthesis of clavine alkaloids
  17. Asymmetric Intramolecular Amination Catalyzed with Cp*Ir-SPDO via Nitrene Transfer for Synthesis of Spiro-Quaternary Indolinone
  18. Regioselective Electrooxidative [3+2] Annulation between Indole and Aniline Derivatives to Construct Functionalized Indolo[2,3-b]indoles
  19. Atroposelective synthesis of biaxial bridged eight-membered terphenyls via a Co/SPDO-catalyzed aerobic oxidative coupling/desymmetrization of phenols
  20. Enantioselective Synthesis of Axially Chiral Sulfone-Containing Styrenes Based on Ion-Exchange Strategy
  21. How achiral Brønsted acid is involved in co-catalyst model with chiral phosphoric acid for construction of quaternary carbon stereocenter
  22. Cooperative Cu/azodiformate system-catalyzed allylic C–H amination of unactivated internal alkenes directed by aminoquinoline
  23. Colorless transparent and thermally stable terphenyl polyimides with various small side groups for substrate application
  24. Bringing Green Organic Electrochemistry to Undergraduates: A Designed Comparison Organic Experiment of Bromination
  25. An Axially Chiral Styrene–Phosphine Ligand for Pd-Catalyzed Asymmetric N-Alkylation of Indoles
  26. Stereoselective Sulfa-Michael/Aldol Reaction Promoted by an Axially Chiral Styrene-Based Organocatalyst
  27. Total Syntheses of Polycyclic Diterpenes Phomopsene, Methyl Phomopsenonate, and iso-Phomopsene via Reorganization of C–C Single Bonds
  28. Asymmetric Intramolecular Hydroalkylation of Internal Olefin with Cycloalkanone to Directly Access Polycyclic Systems
  29. Asymmetric Intramolecular Hydroalkylation of Internal Olefin with Cycloalkanone to Directly Access Polycyclic Systems
  30. Synthetic strategies and mechanistic studies of axially chiral styrenes
  31. Electroreductive fluoroalkylative heteroarylation of unactivated alkenes via an unconventional remote heteroaryl migration
  32. Project-Based Learning in Green Electrochemistry for Undergraduates: An Efficient Synthesis Route of a Natural Product
  33. Axially chiral styrene-based organocatalysts and their application in asymmetric cascade Michael/cyclization reaction
  34. Bioinspired Palladium‐Catalyzed Intramolecular C(sp3)−H Activation for the Collective Synthesis of Proline Natural Products
  35. Bioinspired Palladium‐Catalyzed Intramolecular C(sp3)−H Activation for the Collective Synthesis of Proline Natural Products
  36. Chiral Phosphoric Acid-Catalyzed Enantioselective Dearomative Electrophilic Hydrazination: Access to Chiral Aza-Quaternary Carbon Indolenines
  37. Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli
  38. Highly Site‐ and Enantioselective N—H Functionalization of N‐Monosubstituted Aniline Derivatives Affording Pyrazolones Bearing a Quaternary Stereocenter
  39. Bromine and oxygen redox species mediated highly selective electro-epoxidation of styrene
  40. Electrochemical collective synthesis of labeled pyrroloindoline alkaloids with Freon-type methanes as functional C1 synthons
  41. Terphenyl-based colorless and heat-resistant polyimides with a controlled molecular structure using methyl side groups
  42. Base-Promoted Cobalt-Catalyzed Regio- and Enantioselective para-Friedel–Crafts Alkylation of Aniline Derivatives
  43. Organocatalytic Direct Asymmetric Indolization from Anilines by Enantioselective [3 + 2] Annulation
  44. Paired Electrolysis Enabled Ni-Catalyzed Unconventional Cascade Reductive Thiolation Using Sulfinates
  45. Using Computational Chemistry to Improve Students’ Multidimensional Understanding of Complex Electrophilic Aromatic Substitution Reactions: Further Analysis of the Solvent Effect, Temperature Influence, and Kinetic Behaviors
  46. Correction to “Highly Chemo-, Site-, and Enantioseletive para C–H Aminoalkylation of N-Monosubstituted Aniline Derivatives Affording 3-Amino-2-Oxindoles”
  47. Co-Catalyzed Direct Regio- and Enantioselective Intermolecular γ-Amination of N-Acylpyrazoles
  48. Fe-Catalyzed Sequential C(sp3)–H/N–H Annulation of 2-Methylindoles with Ethyl Trifluoropyruvate at Room Temperature: Construction of Pyrrolo[1,2-α]indoles
  49. Total Synthesis of Fawcettimine-Type Alkaloid, Lycojaponicumin A
  50. Highly Chemo-, Site-, and Enantioseletive para C–H Aminoalkylation of N-Monosubstituted Aniline Derivatives Affording 3-Amino-2-oxindoles
  51. Organocatalytic Enantioselective Construction of Heterocycle-Substituted Styrenes with Chiral Atropisomerism
  52. A dienamine-mediated deconjugative addition/cyclization cascade of γ,γ-disubstituted enals with carboxylic acid-activated enones: a rapid access to highly functionalized γ-lactones
  53. Remote C6-Enantioselective C–H Functionalization of 2,3-Disubstituted Indoles through the Dual H-Bonds and π–π Interaction Strategy Enabled by CPAs
  54. Cobalt-Catalyzed Ortho-C(sp2)–H Amidation of Benzaldehydes with Dioxazolones Using Transient Directing Groups
  55. Lewis Base/Brønsted Acid Co-catalyzed Enantioselective Sulfenylation/Semipinacol Rearrangement of Di- and Trisubstituted Allylic Alcohols
  56. Highly atroposelective synthesis of nonbiaryl naphthalene-1,2-diamine N-C atropisomers through direct enantioselective C-H amination
  57. Copper-Complex-Catalyzed Asymmetric Aerobic Oxidative Cross-Coupling of 2-Naphthols: Enantioselective Synthesis of 3,3′-Substituted C1 -Symmetric BINOLs
  58. Design and synthesis of a novel quinoxaline diamine and its polyimides with high-Tg and red color
  59. Silver-Catalyzed para-Selective C–H Amination of 1-Naphthyl­amides with Azodicarboxylates at Room Temperature
  60. Asymmetric N-Hydroxyalkylation of Indoles with Ethyl Glyoxalates Catalyzed by a Chiral Phosphoric Acid: Highly Enantioselective Synthesis of Chiral N,O-Aminal Indole Derivatives
  61. Electrochemical Semipinacol Rearrangements of Allylic Alcohols: Construction of All-Carbon Quaternary Stereocenters
  62. Dual Directing-Groups-Assisted Redox-Neutral Annulation and Ring Opening of N-Aryloxyacetamides with 1-Alkynylcyclobutanols via Rhodium(III)-Catalyzed C–H/C–C Activations
  63. Asymmetric Organocatalytic Synthesis of 2,3-Allenamides from Hydrogen-Bond-Stabilized Enynamides
  64. Computational and experimental studies on copper-mediated selective cascade C–H/N–H annulation of electron-deficient acrylamide with arynes
  65. Electrochemical halogenation/semi-pinacol rearrangement of allylic alcohols using inorganic halide salt: an eco-friendly route to the synthesis of β-halocarbonyls
  66. Synthesis, structures, and thermodynamics/kinetics properties of three Zn(II) coordination polymers modified by 5-substituted isophthalic acid
  67. Rhodium(III)-Catalyzed Redox-Neutral Cascade [3 + 2] Annulation of N-Phenoxyacetamides with Propiolates via C–H Functionalization/Isomerization/Lactonization
  68. Asymmetric intramolecular Friedel–Crafts reaction catalyzed by a spiropyrrolidine organocatalyst: Enantioselective construction of indolizine and azepine frameworks
  69. Transition Metal-Controlled Direct Regioselective Intermolecular Amidation of C−H Bonds with Azodicarboxylates: Scope, Mechanistic Studies, and Applications
  70. A Facile Approach to Oximes and Ethers by a Tandem NO + ‐Initiated Semipinacol Rearrangement and H‐Elimination
  71. A Facile Approach to Oximes and Ethers by a Tandem NO+ -Initiated Semipinacol Rearrangement and H-Elimination
  72. Electrophilic Trifluoromethylthiolation/Semipinacol Rearrangement: Preparation of β-SCF3 Carbonyl Compounds with α-Quaternary Carbon Center
  73. Metal-Controlled, Regioselective, Direct Intermolecular α- or γ-Amination with Azodicarboxylates
  74. Molecular mechanism of staphylopine-mediated metal acquisition
  75. Experimental and computational studies on H2O-promoted, Rh-catalyzed transient-ligand-free ortho-C(sp2)–H amidation of benzaldehydes with dioxazolones
  76. Recent progress in the isolation, bioactivity, biosynthesis, and total synthesis of natural spiroketals
  77. Copper-Mediated Cascade C–H/N–H Annulation of Indolocarboxamides with Arynes: Construction of Tetracyclic Indoloquinoline Alkaloids
  78. Catalytic Asymmetric Cascade Using Spiro-Pyrrolidine Organocatalyst: Efficient Construction of Hydrophenanthridine Derivatives
  79. Stereoselective Synthesis of Z-Vinylsilanes via Palladium-Catalyzed Direct Intermolecular Silylation of C(sp2)–H Bonds
  80. Copper-Catalyzed Selective ortho-C–H/N–H Annulation of Benzamides with Arynes: Synthesis of Phenanthridinone Alkaloids
  81. Palladium-Catalyzed Direct Intermolecular Amination of Unactivated Methylene C(sp3)–H Bonds with Azodiformates via Bidentate-Chelation Assistance
  82. Palladium-catalyzed direct intermolecular silylation of remote unactivated C(sp3)–H bonds
  83. Tandem C–H oxidation/cyclization/rearrangement and its application to asymmetric syntheses of (−)-brussonol and (−)-przewalskine E
  84. Gold(I)/Copper(II)-Cocatalyzed Tandem Cyclization/Semipinacol Reaction: Construction of 6-Aza/Oxa-Spiro[4.5]decane Skeletons and Formal Synthesis of (±)-Halichlorine
  85. Palladium-catalyzed alkylation of unactivated C(sp3)–H bonds with primary alkyl iodides at room temperature: facile synthesis of β-alkyl α-amino acids
  86. Pd-Catalyzed Monoselective ortho-C–H Alkylation of N-Quinolyl Benzamides: Evidence for Stereoretentive Coupling of Secondary Alkyl Iodides
  87. Total Synthesis of Hibispeptin A via Pd-Catalyzed C(sp3)–H Arylation with Sterically Hindered Aryl Iodides
  88. Palladium-Catalyzed Stereoretentive Olefination of Unactivated C(sp3)–H Bonds with Vinyl Iodides at Room Temperature: Synthesis of β-Vinyl α-Amino Acids
  89. Palladium-catalyzed picolinamide-directed halogenation of ortho C–H bonds of benzylamine substrates
  90. Palladium-catalyzed trifluoroacetate-promoted mono-arylation of the β-methyl group of alanine at room temperature: synthesis of β-arylated α-amino acids through sequential C–H functionalization
  91. Palladium-Catalyzed Picolinamide-Directed Acetoxylation of Unactivated γ-C(sp3)H Bonds of Alkylamines
  92. Copper-Catalyzed Carboxamide-Directed Ortho Amination of Anilines with Alkylamines at Room Temperature
  93. A Synthetic Approach for Constructing the 3/6/6/5-Fused Tetracyclic Skeleton of Tenuipesine A
  94. Toward the natural didemnaketal A: total synthesis of the isomer of didemnaketal A
  95. Use of a Readily Removable Auxiliary Group for the Synthesis of Pyrrolidones by the Palladium-Catalyzed Intramolecular Amination of Unactivated γ C(sp3)H Bonds
  96. Stereoselective Synthesis of β-Alkylated α-Amino Acids via Palladium-Catalyzed Alkylation of Unactivated Methylene C(sp3)–H Bonds with Primary Alkyl Halides
  97. Iodination of Remote Ortho-C–H Bonds of Arenes via Directed SEAr: A Streamlined Synthesis of Tetrahydroquinolines
  98. Synthesis of phenanthridines via palladium-catalyzed picolinamide-directed sequential C–H functionalization
  99. Direct Syntheses of Spiro- and Fused-Hydrofurans by a Tunable Tandem Semipinacol Rearrangement/Oxa-Michael Addition Protocol
  100. Cascade Oxidative Dearomatization/Semipinacol Rearrangement: An Approach to 2-Spirocyclo-3-oxindole Derivatives
  101. Palladium-Catalyzed Picolinamide-Directed Alkylation of Unactivated C(sp3)–H Bonds with Alkyl Iodides
  102. Tandem Semipinacol-Type 1,2-Carbon Migration/Aldol Reaction toward the Construction of [5–6–7] All-Carbon Tricyclic Core of Calyciphylline A-Type Alkaloids
  103. Organocatalytic Asymmetric Direct C sp 3H Functionalization of Ethers: A Highly Efficient Approach to Chiral Spiroethers
  104. Efficient Alkyl Ether Synthesis via Palladium-Catalyzed, Picolinamide-Directed Alkoxylation of Unactivated C(sp3)–H and C(sp2)–H Bonds at Remote Positions
  105. Formal Synthesis of (−)-Cephalotaxine Based on a Tandem Hydroamination/Semipinacol Rearrangement Reaction
  106. Studies on the Total Synthesis of 8-epi-Liphagal
  107. Highly Efficient Syntheses of Azetidines, Pyrrolidines, and Indolines via Palladium Catalyzed Intramolecular Amination of C(sp3)–H and C(sp2)–H Bonds at γ and δ Positions
  108. Selective fluorescent probes for live-cell monitoring of sulphide
  109. Chiral Brønsted Acid-Promoted Enantioselective Desymmetrization in an Intramolecular Schmidt Reaction of Symmetric Azido 1,3-Hexanediones: Asymmetric Synthesis of Azaquaternary Pyrroloazepine Skeletons
  110. Development of the Intramolecular Prins Cyclization/Schmidt Reaction for the Construction of the Azaspiro[4,4]nonane: Application to the Formal Synthesis of (±)-Stemonamine
  111. Direct Sp3α-C–H activation and functionalization of alcohol and ether
  112. Iron-Catalyzed C(sp3)C(sp3) Bond Formation through C(sp3)H Functionalization: A Cross-Coupling Reaction of Alcohols with Alkenes
  113. A RhCl(PPh3)3/BF3·OEt2 co-promoted direct C–C cross-coupling of alcohols at β-position with aldehydes
  114. Cross-Coupling Reaction between Alcohols through sp3CH Activation Catalyzed by a Ruthenium/Lewis Acid System
  115. Tandem Aziridination/Rearrangement Reaction of Allylic Alcohols: An Efficient Approach to 2-Quaternary Mannich Bases
  116. Prolinamide/PPTS-Catalyzed Hajos-Parrish Annulation: Efficient Approach to the Tricyclic Core of Cylindricine-Type Alkaloids
  117. A Direct CC Cross-Coupling of Alcohols at the β-Position with Aldehydes under Co-Promotion of Tris(triphenylphosphine)rhodium Chloride/Boron Trifuoride Etherate
  118. A coupling reaction between tetrahydrofuran and olefins by Rh-catalyzed/Lewis acid-promoted C–H activation
  119. Palladium-Catalyzed/Lewis Acid-Promoted Alkene Dimerization and Cross-Coupling with AlcoholsviaCH Bond Activation
  120. Asymmetric Synthesis of the C(17)–C(28)Subunit of Didemnaketal B
  121. An alternative synthetic approach towards erythrinan and homoerythrinan alkaloids by tandem semipinacol/intramolecular Schmidt reaction
  122. General and Efficient Strategy for Erythrinan and Homoerythrinan Alkaloids:  Syntheses of (±)-3-Demethoxyerythratidinone and (±)-Erysotramidine
  123. Quinine/selectfluor combination induced asymmetric semipinacol rearrangement of allylic alcohols: an effective and enantioselective approach to α-quaternary β-fluoro aldehydes
  124. An Efficient Total Synthesis of (±)-Lycoramine
  125. A General Efficient Strategy forcis-3a-Aryloctahydroindole Alkaloids via Stereocontrolled ZnBr2-Catalyzed Rearrangement of 2,3-Aziridino Alcohols