All Stories

  1. The chromosomal origin of replication as the basis for the spatio-temporal biology of bacteria

    Article • Frontiers in Microbiology, April 2026, Frontiers

    Dr masamichi kohiyama

  2. 60 Years of Studies into the Initiation of Chromosome Replication in Bacteria

    Article • Biomolecules, February 2025, MDPI AG

    Dr masamichi kohiyama, Pr Vic Norris

  3. Open Questions about the Roles of DnaA, Related Proteins, and Hyperstructure Dynamics in the Cell Cycle

    Article • Life, September 2023, MDPI AG

    Dr masamichi kohiyama, Pr Vic Norris

  4. The orin of chromosome replication initiator

    Article • Research in Microbiology, December 2020, Elsevier

    Dr masamichi kohiyama

  5. Trashing of Single-Stranded DNA Generated during Processing of Arrested Replication Fork in E. coli

    Article • Journal of Molecular Biology, November 2013, Elsevier

    Dr masamichi kohiyama

  6. DNA replication defects in a mutant deficient in the thioredoxin homolog YbbN

    Article • Biochemical and Biophysical Research Communications, February 2011, Elsevier

    Dr masamichi kohiyama

  7. formation of anucleoid cells

    Article • Journal of Bacteriology, January 2006, ASM Journals

    Dr masamichi kohiyama

  8. Anormal localization of replication forks observed in mukB mutant

    Article • Molecular Genetics and Genomics, August 2005, Springer Science + Business Media

    Dr masamichi kohiyama

  9. fluorescence microscopic detection of recombinants during conjugation in E.coli

    Article • Science, August 2003, American Association for the Advancement of Science

    Dr masamichi kohiyama

  10. control of gene expression via DNA adenine methylation(Dam)

    Article • Journal of Bacteriology, May 2003, ASM Journals

    Dr masamichi kohiyama

  11. Specificity of elongation factor EF-TU for hydrophobic peptides

    Article • Biochemical and Biophysical Research Communications, August 2002, Elsevier

    Dr masamichi kohiyama

  12. DnaA protein dependent denaturation of negative supercoiled oriC DNA minicircles

    Article • Biochimie, January 2001, Elsevier

    Dr masamichi kohiyama

  13. The origin of DNA replication as a music chair

    Article • Genes to Cells, November 2000, Wiley

    Dr masamichi kohiyama

  14. Initiation of DNA replication in Δcya mutants of Escherichia coli K12

    Article • Biochimie, August 1999, Elsevier

    Dr masamichi kohiyama

  15. Replication cycle dependent association of SeqA to the outer membrane fraction of E. coli

    Article • Biochimie, August 1999, Elsevier

    Dr masamichi kohiyama

  16. Initiation of DNA replication in Δcya mutants of Escherichia coli K12

    Article • Biochimie, August 1999, Elsevier

    Dr masamichi kohiyama

  17. Interaction of DnaK with native proteins and membrane proteins correlates with their accessible hydrophobicity

    Article • Gene, April 1999, Elsevier

    Dr masamichi kohiyama

  18. Hemi‐methylated oriC DNA binding activity found in non‐specific acid phosphatase

    Article • Molecular Microbiology, January 1999, Wiley

    Dr masamichi kohiyama

  19. Increased expression of a hemimethylated oriC binding protein, SeqA, in an aphA mutant

    Article • Biochimie, December 1998, Elsevier

    Dr masamichi kohiyama

  20. Purification of Elongation Factors EF-Tu and EF-G fromEscherichia coliby Covalent Chromatography on Thiol–Sepharose

    Article • Protein Expression and Purification, October 1998, Elsevier

    Dr masamichi kohiyama

  21. DnaJ Potentiates the Interaction between DnaK and α-Helical Peptides

    Article • Biochemical and Biophysical Research Communications, April 1997, Elsevier

    Dr masamichi kohiyama

  22. Co‐ordination between membrane oriC sequestration factors and a chromosome partitioning protein, TolC (MukA)

    Article • Molecular Microbiology, October 1996, Wiley

    Dr masamichi kohiyama

  23. Defect in export and synthesis of the periplasmic galactose receptor MgIB in dnaK mutants of Escherichia coli, and decreased stability of the mgIB mRN

    Article • Microbiology, September 1996, Society for General Microbiology

    Dr masamichi kohiyama

  24. Specificity of DnaK for Arginine/Lysine and Effect of DnaJ on the Amino Acid Specificity of DnaK

    Article • Journal of Biological Chemistry, June 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr masamichi kohiyama

  25. A Novel Cytoplasmic Hemimethylated oriC Binding Activity

    Article • Journal of Biological Chemistry, March 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr masamichi kohiyama

  26. The initiation mess?

    Article • Molecular Microbiology, February 1996, Wiley

    Dr masamichi kohiyama

  27. Reversal by GroES of the GroEL Preference from Hydrophobic Amino Acids toward Hydrophilic Amino Acids

    Article • Journal of Biological Chemistry, May 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr masamichi kohiyama

  28. Importance of the replication origin sequestration in cell division of Escherichia coli

    Article • Biochimie, January 1995, Elsevier

    Dr masamichi kohiyama

  29. Parental strand recognition of the DNA replication origin by the outer membrane in Escherichia coli.

    Article • The EMBO Journal, October 1994, Wiley

    Dr masamichi kohiyama

  30. DnaA independent DNA replication initiated by gamma ray irradiation

    Article • Journal of General Microbiology, November 1993, Society for General Microbiology

    Dr masamichi kohiyama

  31. Impairment of nucleoid segregation and cell division at high osmolarity in a strain of Escherichia coli overproducing the chaperone DnaK

    Article • FEMS Microbiology Letters, October 1993, Oxford University Press (OUP)

    Dr masamichi kohiyama

  32. Autostimulation of the DnaK (HSP 70) ATPase of Escherichia coli

    Article • FEBS Letters, May 1993, Wiley

    Dr masamichi kohiyama

  33. The heat-shock DnaK protein is required for plasmid R1 replication and it is dispensable for plasmid ColE1 replication

    Article • Nucleic Acids Research, January 1993, Oxford University Press (OUP)

    Dr masamichi kohiyama

  34. Potassium ions and changes in bacterial DNA supercoiling under osmotic stress

    Article • FEMS Microbiology Letters, December 1992, Oxford University Press (OUP)

    Dr masamichi kohiyama

  35. Purification of the MglC/E membrane proteins of the binding protein‐dependent galactose transport system of Salmonella typhimurium

    Article • FEBS Letters, June 1992, Wiley

    Dr masamichi kohiyama

  36. DNA Replication: The Regulatory Mechanisms

    Article • January 1992, Springer Science + Business Media

    Dr masamichi kohiyama, Dr Patrick T Hughes

  37. Inhibition of DNA synthesis at the hemimethylated pBR322 origin of replication by a cell membrane fraction

    Article • Nucleic Acids Research, January 1992, Oxford University Press (OUP)

    Dr masamichi kohiyama

  38. Further Characterization of a DNA Replication Inhibitor from the Cell Membrane of Escherichia coli

    Article • January 1992, Springer Science + Business Media

    Dr masamichi kohiyama

  39. Exonuclease activities associated with DNA polymerases α and β of the archaebacterium Halobacterium halobium

    Article • FEBS Journal, May 1991, Wiley

    Dr masamichi kohiyama

  40. Presence of circulating anti‐c‐myb oncogene product antibodies in human sera

    Article • International Journal of Cancer, March 1991, Wiley

    Dr masamichi kohiyama

  41. In vitro roles of Escbericbia coli DnaJ and DnaK heat shock proteins in the replication of oriC plasmids

    Article • March 1991

    Dr masamichi kohiyama

  42. An Archaebacterial Antigen Used to Study Immunological Humoral Response to C-Myc Oncogene Product

    Article • January 1991, Springer Science + Business Media

    Dr masamichi kohiyama

  43. eukaryotic DNA polymerase isolated and purified from an archaebacterium

    Article • January 1991, Springer Science + Business Media

    Dr masamichi kohiyama

  44. Reverse transcriptase in archaebacteria

    Article • FEBS Journal, January 1991, Wiley

    Dr masamichi kohiyama

  45. Bacterial membrane helps control of DNa replication

    Article • Cell, November 1990, Elsevier

    Dr masamichi kohiyama

  46. Circulating antibodies against c‐MYC oncogene product in sera of colorectal cancer patients

    Article • International Journal of Cancer, July 1990, Wiley

    Dr masamichi kohiyama

  47. Dam methylated and hemimethylatedoriC plasmids are replicated symmetrically; a novel and general test of replication symmetry

    Article • June 1989

    Dr masamichi kohiyama

  48. ATP is required for K+ active transport in the archaebacterium Haloferax volcanii

    Article • Archives of Microbiology, May 1989, Springer Science + Business Media

    Dr masamichi kohiyama

  49. dam methylation and the initiation of DNA replication on oriC plasmids

    Article • April 1989

    Dr masamichi kohiyama

  50. affinity of DnaA for cAMP

    Article • Cell, October 1988, Elsevier

    Dr masamichi kohiyama

  51. DNA primase activity found in an α‐like DNA polymerase obtained from Halobacterium halobium

    Article • FEBS Journal, August 1988, Wiley

    Dr masamichi kohiyama

  52. A protein of Halobacterium halobium immunologically related to the v‐myc gene product

    Article • FEBS Letters, January 1988, Wiley

    Dr masamichi kohiyama

  53. DNA polymerase and primase-reverse transcriptase from Halobacterium halobium

    Article • Systematic and Applied Microbiology, March 1986, Elsevier

    Dr masamichi kohiyama

  54. Archae DNA polymerase purification and characterization

    Article • FEBS Journal, October 1985, Wiley

    Dr masamichi kohiyama

  55. Effect of oriC unmethylation on initiation site of DNA replication

    Article • Journal of Molecular Biology, June 1984, Elsevier

    Dr masamichi kohiyama

  56. Studies on the Role of dam Methylation at the Escherichia Coli Chromosome Replication Origin (oriC)

    Article • January 1984, Springer Science + Business Media

    Dr masamichi kohiyama

  57. early demonstration of the importance of DNA helices in repair

    Article • November 1983

    Dr masamichi kohiyama

  58. Stable DNA replication induced by gamma ray irradiation without DnaA depends on RecA

    Article • FEBS Journal, May 1983, Wiley

    Dr masamichi kohiyama

  59. Recognition of Origin of Replication by Initiation Factors in Escherichia Coli

    Article • January 1983, Springer Science + Business Media

    Dr masamichi kohiyama

  60. Recognition sites for a membrane-derived DNA binding protein preparation in the E. coli replication origin

    Article • January 1983

    Dr masamichi kohiyama

  61. Purification of Penicillin‐Binding Protein 3 from Streptococcus pneumoniae

    Article • FEBS Journal, October 1982, Wiley

    Dr masamichi kohiyama

  62. Inhibition of DNA replication in vitro by pefloxacin

    Article • FEBS Letters, August 1982, Wiley

    Dr masamichi kohiyama, Dr Patrick T Hughes

  63. Labelling of pneumococcal penicillin-binding proteins with [ 3 H]propionyl-ampicillin

    Article • FEMS Microbiology Letters, August 1982, Oxford University Press (OUP)

    Dr masamichi kohiyama

  64. A DNA-Binding Protein Specific for the Early Replicated Region of the Chromosome Obtained from Escherichia coli Membrane Fractions

    Article • FEBS Journal, March 1980, Wiley

    Dr masamichi kohiyama

  65. ISOLATION OF DNA-DEPENDENT ATPase I MUTANTS OF E.COLI

    Article • January 1980, Elsevier

    Dr masamichi kohiyama

  66. ISOLATION OF A MEMBRANE PROTEIN HAVING AN AFFINITY TO THE REPLICATION ORIGIN OF E. COLI

    Article • January 1980, Elsevier

    Dr masamichi kohiyama

  67. DNA Research Overview DNA Synthesis: Present and Future Ian Molineux Masamichi Kohiyama

    Article • BioScience, July 1979, Oxford University Press (OUP)

    Dr masamichi kohiyama

  68. DNA Synthesis: Present and Future Ian Molineux Masamichi Kohiyama

    Article • The Quarterly Review of Biology, June 1979, University of Chicago Press

    Dr masamichi kohiyama

  69. DNA-dependent ATPases from Escherichia coli K12

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 1979, Cold Spring Harbor Laboratory Press

    Dr masamichi kohiyama

  70. Evidences for the Existence of Two Steps in DNA Replication Obtained in Toluene- Treated Escherichia coli

    Article • FEBS Journal, October 1978, Wiley

    Dr masamichi kohiyama

  71. DNA Synthesis

    Article • January 1978, Springer Science + Business Media

    Dr masamichi kohiyama

  72. The Role of ATP in E.Coli Chromosome Replication

    Article • January 1978, Springer Science + Business Media

    Dr masamichi kohiyama

  73. Mechanism and Regulation of DNA Replication

    Article • January 1974, Springer Science + Business Media

    Dr masamichi kohiyama

  74. The Role of ATP in Chromosome Replication Studied in Toluenized Escherichia coli

    Article • January 1974, Springer Science + Business Media

    Dr masamichi kohiyama

  75. Isolation of a DNA polymerase fraction active with single-strand DNA and stimulated by ATP

    Article • Journal of Molecular Biology, July 1973, Elsevier

    Dr masamichi kohiyama

  76. Some DNA repair protein participates in stable replication induced by gamma rays

    Article • Nature New Biology, October 1971, Springer Science + Business Media

    Dr masamichi kohiyama

  77. Immediate stop of replication in CRT-266(dnaB) mutant in nonpermissive conditions

    Article • Nature, December 1970, Springer Science + Business Media

    Dr masamichi kohiyama

  78. Stable DNA replication induced by gamma ray irradiation in the absence of active initiator in E.coli

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 1968, Cold Spring Harbor Laboratory Press

    Dr masamichi kohiyama

  79. DNA-MEDIATED TRANSFORMATION IN BACILLUS SUBTILIS WITH SPECIAL REFERENCE TO THE METHOD FOR PREPARING COMPETENT CELLS

    Article • The Journal of General and Applied Microbiology, January 1961, Microbiology Research Foundation

    Dr masamichi kohiyama

  80. Streptomycin iresistant mutant acquired other mutations

    Article • Nature, July 1960, Springer Science + Business Media

    Dr masamichi kohiyama

  81. how to increase competent cells for transformation

    Article • Biochimica et Biophysica Acta, June 1960, Elsevier

    Dr masamichi kohiyama

  82. A hint for the existence of DNA transformation in B.subtilis

    Article • Nature, July 1959, Springer Science + Business Media

    Dr masamichi kohiyama

  83. Genetic interaction observed in Bacillus subtilis

    Article • Molecular Genetics and Genomics, January 1959, Springer Science + Business Media

    Dr masamichi kohiyama