All Stories

  1. On the other side of the membrane: A new role for a luminal protein in the cytoplasm

    Article • European Journal of Biochemistry, May 2026, Wiley

    Erik L Snapp

  2. TUDCA modulates drug bioavailability to regulate resistance to acute ER stress in Saccharomyces cerevisiae

    Article • Molecular Biology of the Cell, February 2025, American Society for Cell Biology (ASCB)

    Erik L Snapp

  3. TUDCA modulates drug bioavailability to regulate resistance to acute ER stress inSaccharomyces cerevisiae

    Article • November 2024, Cold Spring Harbor Laboratory Press

    Erik L Snapp

  4. Size‐dependent secretory protein reflux into the cytosol in association with acute endoplasmic reticulum stress

    Article • Traffic, April 2020, Wiley

    Erik L Snapp

  5. Trans -endocytosis of intact IL-15Rα–IL-15 complex from presenting cells into NK cells favors signaling for proliferation

    Article • Proceedings of the National Academy of Sciences, December 2019, Proceedings of the National Academy of Sciences

    Erik L Snapp

  6. How to design a chalk talk—the million dollar sales pitch

    Article • Molecular Biology of the Cell, June 2019, American Society for Cell Biology (ASCB)

    Erik L Snapp

  7. Size-Dependent Secretory Protein Reflux into the Cytosol in Association with Acute Endoplasmic Reticulum Stress

    Article • March 2019, Cold Spring Harbor Laboratory Press

    Erik L Snapp

  8. Interleukin 2 modulates thymic-derived regulatory T cell epigenetic landscape

    Article • Nature Communications, December 2018, Springer Science + Business Media

    Erik L Snapp

  9. moxMaple3: a Photoswitchable Fluorescent Protein for PALM and Protein Highlighting in Oxidizing Cellular Environments

    Article • Scientific Reports, October 2018, Springer Science + Business Media

    Erik L Snapp

  10. The Development and Enhancement of FRAP as a Key Tool for Investigating Protein Dynamics

    Article • Biophysical Journal, October 2018, Elsevier

    Erik L Snapp

  11. Structure and topology around the cleavage site regulate post-translational cleavage of the HIV-1 gp160 signal peptide

    Article • eLife, July 2017, eLife

    Erik L Snapp

  12. moxDendra2: an inert photoswitchable protein for oxidizing environments

    Article • Chemical Communications, January 2017, Royal Society of Chemistry

    Erik L Snapp

  13. An in vitro compartmentalization-based method for the selection of bond-forming enzymes from large libraries

    Article • Biotechnology and Bioengineering, February 2016, Wiley

    Erik L Snapp

  14. A New Transferrin Receptor Aptamer Inhibits New World Hemorrhagic Fever Mammarenavirus Entry

    Article • Molecular Therapy — Nucleic Acids, January 2016, Elsevier

    Erik L Snapp

  15. Connexin Type and Fluorescent Protein Fusion Tag Determine Structural Stability of Gap Junction Plaques

    Article • Journal of Biological Chemistry, August 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Erik L Snapp

  16. Imaging the Alphavirus Exit Pathway

    Article • Microscopy and Microanalysis, August 2015, Cambridge University Press

    Erik L Snapp

  17. Going Viral with Fluorescent Proteins

    Article • Journal of Virology, July 2015, ASM Journals

    Erik L Snapp

  18. A palette of fluorescent proteins optimized for diverse cellular environments

    Article • Nature Communications, July 2015, Springer Science + Business Media

    Erik L Snapp

  19. Traffic of p24 Proteins and COPII Coat Composition Mutually Influence Membrane Scaffolding

    Article • Current Biology, May 2015, Elsevier

    Erik L Snapp

  20. Engineering and exploitation of a fluorescent HIV-1 gp120 for live cell CD4 binding assays

    Article • Virology, February 2015, Elsevier

    Erik L Snapp

  21. Biochemical and Cellular Analysis of Human Variants of the DYT1 Dystonia Protein, TorsinA/TOR1A

    Article • Human Mutation, July 2014, Wiley

    Erik L Snapp

  22. Allosteric Inhibition of the IRE1α RNase Preserves Cell Viability and Function during Endoplasmic Reticulum Stress

    Article • Cell, July 2014, Elsevier

    Erik L Snapp

  23. A sphingolipid-dependent diffusion barrier confines ER stress to the yeast mother cell

    Article • eLife, May 2014, eLife

    Erik L Snapp

  24. Imaging the Alphavirus Exit Pathway

    Article • Journal of Virology, April 2014, ASM Journals

    Dr Margaret Kielian, Erik L Snapp

  25. Human Liver Cell Trafficking Mutants: Characterization and Whole Exome Sequencing

    Article • PLOS One, January 2014, PLOS

    Erik L Snapp

  26. Approaches to imaging unfolded secretory protein stress in living cells

    Article • Endoplasmic Reticulum Stress in Diseases, January 2014, De Gruyter

    Erik L Snapp, Patrick Lajoie

  27. Fluorescent Proteins in Cellular Organelles: Serious Pitfalls and Some Solutions

    Article • DNA and Cell Biology, November 2013, Mary Ann Liebert Inc

    Erik L Snapp

  28. Probing Endoplasmic Reticulum Dynamics using Fluorescence Imaging and Photobleaching Techniques

    Article • September 2013, Wiley

    Erik L Snapp

  29. Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha 1 ‐antitrypsin deficiency

    Article • Hepatology, March 2013, Wiley

    Erik L Snapp, Dr Elena Miranda

  30. ERdj3 regulates BiP occupancy in living cells

    Article • Journal of Cell Science, February 2013, The Company of Biologists

    Erik L Snapp

  31. Photobleaching Methods to Study Golgi Complex Dynamics in Living Cells

    Article • January 2013, Elsevier

    Erik L Snapp

  32. Detecting Soluble PolyQ Oligomers and Investigating Their Impact on Living Cells Using Split-GFP

    Article • January 2013, Springer Science + Business Media

    Erik L Snapp, Patrick Lajoie

  33. Cysteineless non-glycosylated monomeric blue fluorescent protein, secBFP2, for studies in the eukaryotic secretory pathway

    Article • Biochemical and Biophysical Research Communications, January 2013, Elsevier

    Erik L Snapp

  34. Proinsulin Intermolecular Interactions during Secretory Trafficking in Pancreatic β Cells

    Article • Journal of Biological Chemistry, December 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Erik L Snapp

  35. Unfolded Protein Responses With or Without Unfolded Proteins?

    Article • Cells, November 2012, MDPI AG

    Erik L Snapp

  36. Polymeric Mutants Of ±1-Antitrypsin Impair Protein Mobility Within The Endoplasmic Reticulum And Enhance Susceptibility To The Unfolded Protein Response

    Article • May 2012, American Thoracic Society

    Erik L Snapp

  37. Kar2p availability defines distinct forms of endoplasmic reticulum stress in living cells

    Article • Molecular Biology of the Cell, March 2012, American Society for Cell Biology (ASCB)

    Erik L Snapp

  38. Assessing the Tendency of Fluorescent Proteins to Oligomerize Under Physiologic Conditions

    Article • Traffic, February 2012, Wiley

    Erik L Snapp

  39. Changes in BiP availability reveal hypersensitivity to acute endoplasmic reticulum stress in cells expressing mutant huntingtin

    Article • Journal of Cell Science, February 2012, The Company of Biologists

    Erik L Snapp

  40. ERdj4 Protein Is a Soluble Endoplasmic Reticulum (ER) DnaJ Family Protein That Interacts with ER-associated Degradation Machinery

    Article • Journal of Biological Chemistry, January 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Erik L Snapp

  41. Sec24p and Sec16p cooperate to regulate the GTP cycle of the COPII coat

    Article • The EMBO Journal, December 2011, Wiley

    Erik L Snapp

  42. Activating Photoactivatable Proteins with Laser Light to Visualize Membrane Systems and Membrane Traffic in Living Cells

    Article • Cold Spring Harbor Protocols, November 2011, Cold Spring Harbor Laboratory Press

    Erik L Snapp

  43. Imaging of Membrane Systems and Membrane Traffic in Living Cells

    Article • Cold Spring Harbor Protocols, November 2011, Cold Spring Harbor Laboratory Press

    Erik L Snapp

  44. Photobleaching Regions of Living Cells to Monitor Membrane Traffic

    Article • Cold Spring Harbor Protocols, November 2011, Cold Spring Harbor Laboratory Press

    Erik L Snapp

  45. Time-Lapse Imaging of Membrane Traffic in Living Cells

    Article • Cold Spring Harbor Protocols, November 2011, Cold Spring Harbor Laboratory Press

    Erik L Snapp

  46. Mechanism of Collapse of Endoplasmic Reticulum Cisternae During African Swine Fever Virus Infection

    Article • Traffic, October 2011, Wiley

    Erik L Snapp

  47. Changes in BiP availability reveal hypersensitivity to acute endoplasmic reticulum stress in cells expressing mutant huntingtin

    Article • Journal of Cell Science, September 2011, The Company of Biologists

    Erik L Snapp

  48. Maturation of BRI2 generates a specific inhibitor that reduces APP processing at the plasma membrane and in endocytic vesicles

    Article • Neurobiology of Aging, August 2011, Elsevier

    Erik L Snapp

  49. Alcohol Disrupts Endoplasmic Reticulum Function and Protein Secretion in Hepatocytes

    Article • Alcoholism Clinical and Experimental Research, July 2011, Wiley

    Erik L Snapp

  50. Static retention of the lumenal monotopic membrane protein torsinA in the endoplasmic reticulum

    Article • The EMBO Journal, July 2011, Wiley

    Erik L Snapp

  51. Superfolder GFP Is Fluorescent in Oxidizing Environments When Targeted via the Sec Translocon

    Article • Traffic, February 2011, Wiley

    Erik L Snapp

  52. Formation and Toxicity of Soluble Polyglutamine Oligomers in Living Cells

    Article • PLOS One, December 2010, PLOS

    Erik L Snapp, Patrick Lajoie

  53. BiP Modulates the Affinity of Its Co-chaperone ERj1 for Ribosomes

    Article • Journal of Biological Chemistry, September 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Erik L Snapp

  54. BiP Availability Distinguishes States of Homeostasis and Stress in the Endoplasmic Reticulum of Living Cells

    Article • Molecular Biology of the Cell, June 2010, American Society for Cell Biology (ASCB)

    Erik L Snapp

  55. Structural Insights into Triglyceride Storage Mediated by Fat Storage-Inducing Transmembrane (FIT) Protein 2

    Article • PLOS One, May 2010, PLOS

    Erik L Snapp

  56. Evolutionary Gain of Function for the ER Membrane Protein Sec62 from Yeast to Humans

    Article • Molecular Biology of the Cell, March 2010, American Society for Cell Biology (ASCB)

    Prof Martin Jung, Erik L Snapp

  57. Fluorescent proteins: a cell biologist's user guide

    Article • Trends in Cell Biology, November 2009, Elsevier

    Erik L Snapp

  58. An essential role for ATP binding and hydrolysis in the chaperone activity of GRP94 in cells

    Article • Proceedings of the National Academy of Sciences, July 2009, Proceedings of the National Academy of Sciences

    Erik L Snapp

  59. LULL1 Retargets TorsinA to the Nuclear Envelope Revealing an Activity That Is Impaired by the DYT1 Dystonia Mutation

    Article • Molecular Biology of the Cell, June 2009, American Society for Cell Biology (ASCB)

    Erik L Snapp

  60. Evolutionarily conserved gene family important for fat storage

    Article • Proceedings of the National Academy of Sciences, January 2008, Proceedings of the National Academy of Sciences

    Erik L Snapp

  61. Erratum

    Article • Critical Reviews in Plant Sciences, October 2007, Taylor & Francis

    Erik L Snapp

  62. High Speed Photomanipulation Applications

    Article • Microscopy and Microanalysis, August 2007, Cambridge University Press

    Erik L Snapp

  63. Rational Design and Evaluation of FRET Experiments to Measure Protein Proximities in Cells

    Article • Current Protocols in Cell Biology, September 2006, Wiley

    Erik L Snapp

  64. Endoplasmic reticulum architecture: structures in flux

    Article • Current Opinion in Cell Biology, August 2006, Elsevier

    Erik L Snapp

  65. Monitoring chaperone engagement of substrates in the endoplasmic reticulum of live cells

    Article • Proceedings of the National Academy of Sciences, April 2006, Proceedings of the National Academy of Sciences

    Erik L Snapp

  66. Golgi Inheritance in Mammalian Cells Is Mediated through Endoplasmic Reticulum Export Activities

    Article • Molecular Biology of the Cell, February 2006, American Society for Cell Biology (ASCB)

    Erik L Snapp

  67. Regulation of Protein Compartmentalization Expands the Diversity of Protein Function

    Article • Developmental Cell, October 2005, Elsevier

    Erik L Snapp

  68. Design and Use of Fluorescent Fusion Proteins in Cell Biology

    Article • Current Protocols in Cell Biology, June 2005, Wiley

    Erik L Snapp

  69. Stable Binding of ATF6 to BiP in the Endoplasmic Reticulum Stress Response

    Article • Molecular and Cellular Biology, February 2005, ASM Journals

    Erik L Snapp

  70. Glycan-independent Role of Calnexin in the Intracellular Retention of Charcot-Marie-Tooth 1A Gas3/PMP22 Mutants

    Article • Journal of Biological Chemistry, November 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Erik L Snapp

  71. The Fusome Mediates Intercellular Endoplasmic Reticulum Connectivity in Drosophila Ovarian Cysts

    Article • Molecular Biology of the Cell, October 2004, American Society for Cell Biology (ASCB)

    Erik L Snapp

  72. Endoplasmic Reticulum Export Sites and Golgi Bodies Behave as Single Mobile Secretory Units in Plant Cells

    Article • The Plant Cell, June 2004, American Society of Plant Biologists (ASPB)

    Erik L Snapp

  73. The organization of engaged and quiescent translocons in the endoplasmic reticulum of mammalian cells

    Article • Journal of Cell Biology, March 2004, Rockefeller University Press

    Erik L Snapp

  74. Formation of stacked ER cisternae by low affinity protein interactions

    Article • Journal of Cell Biology, October 2003, Rockefeller University Press

    Erik L Snapp

  75. Measuring Protein Mobility by Photobleaching GFP Chimeras in Living Cells

    Article • Current Protocols in Cell Biology, June 2003, Wiley

    Erik L Snapp

  76. Active translocon complexes labeled with GFP–Dad1 diffuse slowly as large polysome arrays in the endoplasmic reticulum

    Article • Journal of Cell Biology, August 2002, Rockefeller University Press

    Erik L Snapp

  77. Membrane Protein Transport between the Endoplasmic Reticulum and the Golgi in Tobacco Leaves Is Energy Dependent but Cytoskeleton Independent

    Article • The Plant Cell, June 2002, American Society of Plant Biologists (ASPB)

    Erik L Snapp

  78. Studying protein dynamics in living cells

    Article • Nature Reviews Molecular Cell Biology, June 2001, Springer Science + Business Media

    Erik L Snapp

  79. Dynamics and retention of misfolded proteins in native ER membranes

    Article • Nature Cell Biology, April 2000, Springer Science + Business Media

    Erik L Snapp

  80. Characterization of a Targeting Motif for a Flagellar Membrane Protein inLeishmania enriettii

    Article • Journal of Biological Chemistry, October 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Erik L Snapp

  81. Cytoskeletal Association Is Important for Differential Targeting of Glucose Transporter Isoforms in Leishmania

    Article • Journal of Cell Biology, December 1997, Rockefeller University Press

    Erik L Snapp

  82. Classification and Indexing Practice (Book Review)

    Article • College & Research Libraries, September 1978, American Library Association

    Erik L Snapp

  83. Local Library Cooperation (Book Review)

    Article • College & Research Libraries, September 1975, American Library Association

    Erik L Snapp

  84. Endoplasmic Reticulum Biogenesis

    Article • Springer Science + Business Media

    Erik L Snapp

  85. FRAP and Other Photobleaching Methods

    Article • Springer Science + Business Media

    Erik L Snapp

  86. Imaging Cellular Proteins and Structures: Smaller, Brighter, and Faster

    Article • Wiley

    Erik L Snapp