All Stories

  1. p38 links RAS to GATA2

    Article • EMBO Reports, August 2014, EMBO

    Professor Manuela Baccarini

  2. “RAF” neighborhood: Protein–protein interaction in the Raf/Mek/Erk pathway

    Article • FEBS Letters, June 2014, Wiley

    Professor Manuela Baccarini

  3. BRAF inhibitors suppress apoptosis through off-target inhibition of JNK signaling

    Article • eLife, November 2013, eLife

    Professor Manuela Baccarini, Dr Rosamaria Ruggieri, Dr Sandra S Ojeda

  4. Skin Tumorigenesis Stimulated by Raf Inhibitors Relies Upon Raf Functions That Are Dependent and Independent of ERK

    Article • Cancer Research, October 2013, American Association for Cancer Research (AACR)

    Professor Manuela Baccarini

  5. EGFR-Ras-Raf Signaling in Epidermal Stem Cells: Roles in Hair Follicle Development, Regeneration, Tissue Remodeling and Epidermal Cancers

    Article • International Journal of Molecular Sciences, September 2013, MDPI AG

    Professor Manuela Baccarini

  6. RKIP regulates MAP kinase signaling in cells with defective B-Raf activity

    Article • Cellular Signalling, May 2013, Elsevier

    Professor Manuela Baccarini

  7. MEK1 Is Required for PTEN Membrane Recruitment, AKT Regulation, and the Maintenance of Peripheral Tolerance

    Article • Molecular Cell, April 2013, Elsevier

    Professor Manuela Baccarini

  8. Selective Requirement of PI3K/PDK1 Signaling for Kras Oncogene-Driven Pancreatic Cell Plasticity and Cancer

    Article • Cancer Cell, March 2013, Elsevier

    Professor Manuela Baccarini

  9. B-Raf and C-Raf Are Required for Melanocyte Stem Cell Self-Maintenance

    Article • Cell Reports, October 2012, Elsevier

    Professor Manuela Baccarini

  10. Essential, non-redundant roles of B-Raf and Raf-1 in Ras-driven skin tumorigenesis

    Article • Oncogene, June 2012, Springer Science + Business Media

    Professor Manuela Baccarini

  11. ERK Signaling, But Not c-Raf, Is Required for Gonadotropin-Releasing Hormone (GnRH)-Induced Regulation of Nur77 in Pituitary Gonadotropes

    Article • Endocrinology, February 2012, Endocrine Society

    Professor Manuela Baccarini

  12. Angiogenic Sprouting Requires the Fine Tuning of Endothelial Cell Cohesion by the Raf-1/Rok-α Complex

    Article • Developmental Cell, January 2012, Elsevier

    Professor Manuela Baccarini

  13. Conservation of Salmonella Infection Mechanisms in Plants and Animals

    Article • PLoS ONE, September 2011, PLOS

    Professor Manuela Baccarini, Dr Adam Schikora

  14. Raf kinases in cancer–roles and therapeutic opportunities

    Article • Oncogene, May 2011, Springer Science + Business Media

    Professor Manuela Baccarini

  15. C-Raf Is Required for the Initiation of Lung Cancer by K-RasG12D

    Article • Cancer Discovery, May 2011, American Association for Cancer Research (AACR)

    Professor Manuela Baccarini

  16. c-Raf, but Not B-Raf, Is Essential for Development of K-Ras Oncogene-Driven Non-Small Cell Lung Carcinoma

    Article • Cancer Cell, May 2011, Elsevier

    Professor Manuela Baccarini

  17. Partner exchange: protein–protein interactions in the Raf pathway

    Article • Trends in Biochemical Sciences, December 2010, Elsevier

    Professor Manuela Baccarini

  18. Targets of Raf in tumorigenesis

    Article • Carcinogenesis, January 2010, Oxford University Press (OUP)

    Professor Manuela Baccarini

  19. Deciphering Signaling Pathways In Vivo: The Ras/Raf/Mek/Erk Cascade

    Article • January 2010, Springer Science + Business Media

    Professor Manuela Baccarini

  20. Disruption of epidermal specific Stat3 expression and delayed skin tumor development in HPV8 transgenic mice

    Article • Cytokine, October 2009, Elsevier

    Professor Manuela Baccarini, Professor Marco De Andrea

  21. Raf-1 Addiction in Ras-Induced Skin Carcinogenesis

    Article • Cancer Cell, August 2009, Elsevier

    Professor Manuela Baccarini

  22. A Mek1–Mek2 heterodimer determines the strength and duration of the Erk signal

    Article • Nature Structural & Molecular Biology, February 2009, Springer Science + Business Media

    Professor Manuela Baccarini

  23. Raf Protects Against Colitis by Promoting Mouse Colon Epithelial Cell Survival Through NF-κB

    Article • Gastroenterology, August 2008, Elsevier

    Professor Manuela Baccarini

  24. B-Raf is required for ERK activation and tumor progression in a mouse model of pancreatic β-cell carcinogenesis

    Article • Oncogene, May 2008, Springer Science + Business Media

    Professor Manuela Baccarini

  25. RASSF1A Elicits Apoptosis through an MST2 Pathway Directing Proapoptotic Transcription by the p73 Tumor Suppressor Protein

    Article • Molecular Cell, September 2007, Elsevier

    Professor Manuela Baccarini, Dr David Matallanas

  26. Raf kinase signaling functions in sensory neuron differentiation and axon growth in vivo

    Article • Nature Neuroscience, March 2007, Springer Science + Business Media

    Professor Manuela Baccarini, Dr Jian Zhong

  27. Second nature: Biological functions of the Raf‐1 “kinase”

    Article • FEBS Letters, March 2005, Wiley

    Professor Manuela Baccarini

  28. Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis

    Article • Journal of Clinical Investigation, October 2004, American Society for Clinical Investigation

    Professor Manuela Baccarini

  29. Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis

    Article • Journal of Clinical Investigation, October 2004, American Society for Clinical Investigation

    Professor Manuela Baccarini

  30. Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock

    Article • Nature Immunology, April 2003, Springer Science + Business Media

    Professor Manuela Baccarini, David Levy

  31. Raf-1 Antagonizes Erythroid Differentiation by Restraining Caspase Activation

    Article • The Journal of Experimental Medicine, November 2002, Rockefeller University Press

    Professor Manuela Baccarini

  32. An old kinase on a new path: Raf and apoptosis

    Article • Cell Death and Differentiation, July 2002, Springer Science + Business Media

    Professor Manuela Baccarini

  33. Opposite effects of different doses of MCSF on ERK phosphorylation and cell proliferation in macrophages

    Article • Oncogene, May 2002, Springer Science + Business Media

    Professor Manuela Baccarini, Elisabetta Rovida

  34. Raf‐1 and B‐Raf proteins have similar regional distributions but differential subcellular localization in adult rat brain

    Article • European Journal of Neuroscience, June 1999, Wiley

    Professor Manuela Baccarini

  35. Activation of bcl‐2 suppressible 40 and 44 kDa p38‐like kinases during apoptosis of early and late B lymphocytic cell lines

    Article • FEBS Letters, May 1998, Wiley

    Professor Manuela Baccarini

  36. Altered Growth Factor Response in Myeloid Progenitor Cell Mutants Derived after Retroviral Insertlonal Mutagenesis

    Article • January 1996, Springer Science + Business Media

    Professor Manuela Baccarini

  37. Ras/MAP kinase-dependent and -independent signaling pathways target distinct ternary complex factors.

    Article • Genes & Development, August 1994, Cold Spring Harbor Laboratory Press

    Professor Manuela Baccarini

  38. Bacterially Expressed Murine CSF-1 Possesses Agonistic Activity in Its Monomeric Form

    Article • Biochemical and Biophysical Research Communications, April 1993, Elsevier

    Professor Manuela Baccarini

  39. Upregulation of Lineage Specific Receptors and Ligands in Multipotential Progenitor Cells is Part of an Endogenous Program of Differentiation

    Article • Growth Factors, January 1993, Taylor & Francis

    Professor Manuela Baccarini

  40. Colony Stimulating Factor-1

    Article • January 1990, Springer Science + Business Media

    Professor Manuela Baccarini

  41. Liver‐associated macrophage precursor cells proliferate under impairment of regular hemopoiesis

    Article • European Journal of Immunology, May 1988, Wiley

    Professor Manuela Baccarini

  42. Extracellular killing of Leishmania promastigotes and amastigotes by macrophage precursors derived from bone marrow cultures

    Article • The Journal of Experimental Medicine, April 1988, Rockefeller University Press

    Professor Manuela Baccarini

  43. Organ-Associated Macrophage Precursor Cells as Effector Cells Against Tumor Targets and Microorganisms

    Article • January 1987, Springer Science + Business Media

    Professor Manuela Baccarini

  44. Functional heterogeneity of murine macrophage precursor cells from spleen and bone marrow

    Article • Cellular Immunology, September 1986, Elsevier

    Professor Manuela Baccarini

  45. A fast and objective assay for cell mediated intra- and extracellular killing of Leishmania promastigotes

    Article • Journal of Immunological Methods, February 1986, Elsevier

    Professor Manuela Baccarini

  46. Liver‐associated macrophage precursors as natural cytotoxic effectors against Candida albicans and Yac‐1 cells

    Article • European Journal of Immunology, January 1986, Wiley

    Professor Manuela Baccarini

  47. Killing of Yeast, Germ-tube and Mycelial Forms of Candida albicans by Murine Effectors as Measured by a Radiolabel Release Microassay

    Article • Microbiology, March 1985, Society for General Microbiology

    Professor Manuela Baccarini

  48. Enhancement of natural killer cell activity in mice by treatment with a thymic factor

    Article • Cancer Immunology Immunotherapy, June 1984, Springer Science + Business Media

    Professor Manuela Baccarini

  49. Modulating Effects of Thymic Factors on Natural Cell-Mediated Reactivities of Natural and Cyclophosphamide-Treated Mice

    Article • January 1984, Springer Science + Business Media

    Professor Manuela Baccarini

  50. Phagocytic killing of Candida albicans by different murine effector cells

    Article • Medical Mycology, January 1983, Oxford University Press (OUP)

    Professor Manuela Baccarini

  51. A radiolabel release microassay for phagocytic killing of Candida albicans

    Article • Journal of Immunological Methods, August 1982, Elsevier

    Professor Manuela Baccarini

  52. Influence of thymosin α1 on natural resistance and cytotoxicity against (CA)

    Article • International Journal of Immunopharmacology, January 1982, Elsevier

    Professor Manuela Baccarini