All Stories

  1. ERK5 is activated by oncogenic BRAF and promotes melanoma growth

    Article • Oncogene, February 2018, Nature

    Elisabetta Rovida

  2. Targeting chronic myeloid leukemia stem cells with the hypoxia-inducible factor inhibitor acriflavine

    Article • Blood, June 2017, American Society of Hematology

    Elisabetta Rovida

  3. The Leukemic Stem Cell Niche: Adaptation to “Hypoxia” versus Oncogene Addiction

    Article • Stem Cells International, January 2017, Hindawi Publishing Corporation

    Nathalie Mazure, Elisabetta Rovida, Matteo Lulli

  4. Low-dose methotrexate enhances cycling of highly anaplastic cancer cells

    Article • Cell Cycle, November 2016, Taylor & Francis

    Elisabetta Rovida

  5. Different BCR/Abl protein suppression patterns as a converging trait of Chronic Myeloid Leukemia cell adaptation to energy restriction

    Article • Oncotarget, November 2016, Impact Journals, LLC

    Elisabetta Rovida

  6. Fibronectin induces macrophage migration through a SFK-FAK/CSF-1R pathway

    Article • Cell Adhesion & Migration, September 2016, Taylor & Francis

    Elisabetta Rovida

  7. Crosstalk between MAPK and HH_GLI signaling in cancer

    Article • Seminars in Cancer Biology, December 2015, Elsevier

    Elisabetta Rovida

  8. The complex metabolic network gearing the G1/S transition in leukemic stem cells: Hints to a rational use of antineoplastic agents

    Article • Oncotarget, October 2015, Impact Journals, LLC

    Elisabetta Rovida

  9. PGE2 synergizes with CSF-1R

    Article • The FASEB Journal, March 2015, Federation of American Societies For Experimental Biology (FASEB)

    Professor Sandra Donnini, Elisabetta Rovida

  10. Hypoxia up-regulates SERPINB3 through HIF-2α in human liver cancer cells

    Article • Oncotarget, February 2015, Impact Journals, LLC

    Elisabetta Rovida

  11. Positive correlation of HIF2α and SERPINB3 in human hepatocellular carcinoma: selectivity and prognostic implications

    Article • Digestive and Liver Disease, February 2015, Elsevier

    Elisabetta Rovida

  12. Colony-Stimulating Factor-1 Receptor in the Polarization of Macrophages: A Target for Turning Bad to Good Ones?

    Article • Journal of Clinical & Cellular Immunology, January 2015, OMICS Publishing Group

    Elisabetta Rovida

  13. Lipid rafts: integrated platforms for vascular organization offering therapeutic opportunities

    Article • Cellular and Molecular Life Sciences, January 2015, Springer Science + Business Media

    Elisabetta Rovida

  14. The metabolically-modulated stem cell niche: a dynamic scenario regulating cancer cell phenotype and resistance to therapy

    Article • Cell Cycle, October 2014, Taylor & Francis

    Elisabetta Rovida

  15. The mitogen-activated protein kinase ERK5 regulates the development and growth of hepatocellular carcinoma

    Article • Gut, September 2014, BMJ

    Elisabetta Rovida

  16. 786: The mitogen-activated protein kinase ERK5 regulates the development and growth of hepatocellular carcinoma

    Article • European Journal of Cancer, July 2014, Elsevier

    Elisabetta Rovida

  17. Possible mechanisms and function of nuclear trafficking of the colony-stimulating factor-1 receptor

    Article • Cellular and Molecular Life Sciences, June 2014, Springer Science + Business Media

    Elisabetta Rovida

  18. One more stem cell niche: how the sensitivity of chronic myeloid leukemia cells to imatinib mesylate is modulated within a "hypoxic" environment

    Article • Hypoxia, January 2014, Taylor & Francis

    Elisabetta Rovida

  19. Chromatin-associated CSF-1R binds to the promoter of proliferation-related genes in breast cancer cells

    Article • Oncogene, December 2013, Nature

    Elisabetta Rovida

  20. Correction to Barbetti V, et al. Epigenetics Volume 8, Issue 2; pp. 210–9

    Article • Epigenetics, December 2013, Taylor & Francis

    Elisabetta Rovida

  21. Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets

    Article • Cell Cycle, November 2013, Taylor & Francis

    Elisabetta Rovida

  22. The Culture-Repopulating Ability Assays and Incubation in Low Oxygen: A Simple Way to Test Drugs on Leukaemia Stem or Progenitor Cells

    Article • Current Pharmaceutical Design, July 2013, Bentham Science Publishers

    Elisabetta Rovida

  23. AML1/ETO sensitizes via TRAIL acute myeloid leukemia cells to the pro-apoptotic effects of hypoxia

    Article • Cell Death and Disease, March 2013, Nature

    Elisabetta Rovida

  24. Time- and residue-specific differences in histone acetylation induced by VPA and SAHA in AML1/ETO-positive leukemia cells

    Article • Epigenetics, February 2013, Taylor & Francis

    Elisabetta Rovida

  25. The involvement of a Nanog, Klf4 and c-Myc transcriptional circuitry in the intertwining between neoplastic progression and reprogramming

    Article • Cell Cycle, January 2013, Taylor & Francis

    Elisabetta Rovida

  26. The Colony-Stimulating Factor-1 (CSF-1) Receptor Sustains ERK1/2 Activation and Proliferation in Breast Cancer Cell Lines

    Article • PLoS ONE, November 2011, PLOS

    Elisabetta Rovida

  27. Hypoxia Selects Bortezomib-Resistant Stem Cells of Chronic Myeloid Leukemia

    Article • PLoS ONE, February 2011, PLOS

    Elisabetta Rovida

  28. Glucose availability in hypoxia regulates the selection of chronic myeloid leukemia progenitor subsets with different resistance to imatinib-mesylate

    Article • Haematologica, November 2010, Ferrata Storti Foundation (Haematologica)

    Elisabetta Rovida

  29. Correction: Granulocyte Maturation after Butyrate Treatment of Leukemic Blasts

    Article • Cancer Research, November 2008, American Association for Cancer Research (AACR)

    Elisabetta Rovida

  30. p38 and cancer: Yang gets yin

    Article • Cancer Biology & Therapy, August 2008, Taylor & Francis

    Elisabetta Rovida

  31. ERK5/BMK1 Is Indispensable for Optimal Colony-Stimulating Factor 1 (CSF-1)-Induced Proliferation in Macrophages in a Src-Dependent Fashion

    Article • The Journal of Immunology, March 2008, The American Association of Immunologists

    Elisabetta Rovida

  32. ERK5 differentially regulates PDGF-induced proliferation and migration of hepatic stellate cells

    Article • Journal of Hepatology, January 2008, Elsevier

    Elisabetta Rovida

  33. Selective anti-leukaemic activity of low-dose histone deacetylase inhibitor ITF2357 on AML1/ETO-positive cells

    Article • Oncogene, September 2007, Nature

    Elisabetta Rovida

  34. Severe Hypoxia Defines Heterogeneity and Selects Highly Immature Progenitors Within Clonal Erythroleukemia Cells

    Article • Stem Cells, May 2007, Wiley

    Elisabetta Rovida

  35. The c-Jun-N-terminal-Kinase inhibitor SP600125 enhances the butyrate derivative D1-induced apoptosis via caspase 8 activation in Kasumi 1 t(8;21) acute myeloid leukaemia cells

    Article • British Journal of Haematology, December 2006, Wiley

    Elisabetta Rovida

  36. Hypoxia suppresses BCR/Abl and selects imatinib-insensitive progenitors within clonal CML populations

    Article • Leukemia, May 2006, Nature

    Elisabetta Rovida

  37. 332 Activation of ERK5, a member of the mapk family, differentially regulates proliferation and migration of hepatic stellate cells

    Article • Journal of Hepatology, April 2006, Elsevier

    Elisabetta Rovida

  38. Focal adhesion kinase is redistributed to focal complexes and mediates cell spreading in macrophages in response to M-CSF

    Article • Biological Chemistry, January 2005, De Gruyter

    Elisabetta Rovida

  39. Corrections

    Article • Cancer Research, May 2004, American Association for Cancer Research (AACR)

    Elisabetta Rovida

  40. Tryptophan availability selectively limits NO-synthase induction in macrophages

    Article • Journal of Leukocyte Biology, January 2003, Society for Leukocyte Biology

    Elisabetta Rovida

  41. Low M r Phosphotyrosine Protein Phosphatase Associates and Dephosphorylates p125 Focal Adhesion Kinase, Interfering with Cell Motility and Spreading

    Article • Journal of Biological Chemistry, June 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Elisabetta Rovida

  42. Opposite effects of different doses of MCSF on ERK phosphorylation and cell proliferation in macrophages

    Article • Oncogene, May 2002, Springer Science + Business Media

    Professor Manuela Baccarini, Elisabetta Rovida

  43. Transmodulation of Cell Surface Regulatory Molecules via Ectodomain Shedding

    Article • Biological Chemistry, January 2002, De Gruyter

    Elisabetta Rovida

  44. TNF- -Converting Enzyme Cleaves the Macrophage Colony-Stimulating Factor Receptor in Macrophages Undergoing Activation

    Article • The Journal of Immunology, February 2001, The American Association of Immunologists

    Elisabetta Rovida

  45. The expansion of murine bone marrow cells preincubated in hypoxia as an in vitro indicator of their marrow-repopulating ability

    Article • Leukemia, April 2000, Nature

    Elisabetta Rovida

  46. Incubation of murine bone marrow cells in hypoxia ensures the maintenance of marrow-repopulating ability together with the expansion of committed progenitors

    Article • British Journal of Haematology, February 2000, Wiley

    Elisabetta Rovida

  47. Low M r phosphotyrosine protein phosphatase activity on fibroblast growth factor receptor is not associated with enzyme translocation

    Article • FEBS Letters, October 1999, Wiley

    Elisabetta Rovida

  48. The Low-Molecular-Weight Phosphotyrosine Protein Phosphatase, when Overexpressed, Reduces the Mitogenic Response to Macrophage Colony-Stimulating Factor and Tyrosine Phosphorylation of Its Receptor

    Article • Biochemical and Biophysical Research Communications, December 1998, Elsevier

    Elisabetta Rovida

  49. INTERLEUKIN 2 DOWN-MODULATES THE MACROPHAGE COLONY-STIMULATING FACTOR RECEPTOR IN MURINE MACROPHAGES

    Article • Cytokine, June 1996, Elsevier

    Elisabetta Rovida