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  1. Platelets derived citrullinated proteins and microparticles are potential autoantibodies ACPA targets in RA patients

    Article • Frontiers in Immunology, January 2023, Frontiers

    Docent Kutty Selva Nandakumar

  2. Vaccines and Vaccine Adjuvants for Infectious Diseases and Autoimmune Diseases

    Article • Vaccines, January 2023, MDPI AG

    Docent Kutty Selva Nandakumar

  3. Comparative studies on mannan and imiquimod induced experimental plaque psoriasis inflammation in inbred mice

    Article • Clinical & Experimental Immunology, January 2023, Oxford University Press (OUP)

    Docent Kutty Selva Nandakumar

  4. Kaempferol modulates IFN-γ induced JAK-STAT signaling pathway and ameliorates imiquimod-induced psoriasis-like skin lesions

    Article • International Immunopharmacology, January 2023, Elsevier

    Docent Kutty Selva Nandakumar

  5. Editorial: Systemic lupus erythematosus - predisposition factors, pathogenesis, diagnosis, treatment and disease models

    Article • Frontiers in Immunology, December 2022, Frontiers

    Docent Kutty Selva Nandakumar

  6. Small molecule SMU-CX24 targeting toll-like receptor 3 counteracts inflammation: A novel approach to atherosclerosis therapy

    Article • Acta Pharmaceutica Sinica B, September 2022, Elsevier

    Docent Kutty Selva Nandakumar

  7. HAPLN1 Affects Cell Viability and Promotes the Pro-Inflammatory Phenotype of Fibroblast-Like Synoviocytes

    Article • Frontiers in Immunology, June 2022, Frontiers

    Docent Kutty Selva Nandakumar

  8. Estrogen Acts Through Estrogen Receptor-β to Promote Mannan-Induced Psoriasis-Like Skin Inflammation

    Article • Frontiers in Immunology, May 2022, Frontiers

    Docent Kutty Selva Nandakumar

  9. Characterization of chronic relapsing antibody mediated arthritis in mice with a mutation in Ncf1 causing reduced oxidative burst

    Article • Molecular Biomedicine, May 2022, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  10. Proteus mirabilis Vesicles Induce Mitochondrial Apoptosis by Regulating miR96-5p/Abca1 to Inhibit Osteoclastogenesis and Bone Loss

    Article • Frontiers in Immunology, February 2022, Frontiers

    Docent Kutty Selva Nandakumar

  11. A Perspective on the Roles of Adjuvants in Developing Highly Potent COVID-19 Vaccines

    Article • Viruses, February 2022, MDPI AG

    Docent Kutty Selva Nandakumar

  12. Gancao Nurish-Yin Decoction medicated serum inhibits growth and migration of ovarian cancer cells: network pharmacology-based analysis and biological validation

    Article • Pharmacological Research - Modern Chinese Medicine, February 2022, Elsevier

    Docent Kutty Selva Nandakumar

  13. Targeting microRNA for improved skin health

    Article • Health Science Reports, October 2021, Wiley

    Docent Kutty Selva Nandakumar

  14. Albumin/Globulin Ratio as Yin–Yang in Rheumatoid Arthritis and Its Correlation to Inflamm-Aging Cytokines

    Article • Journal of Inflammation Research, October 2021, Taylor & Francis

    Docent Kutty Selva Nandakumar

  15. Polymorphic estrogen receptor binding site causes Cd2-dependent sex bias in the susceptibility to autoimmune diseases

    Article • Nature Communications, September 2021, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  16. Current Progress in the Development of Zika Virus Vaccines

    Article • Vaccines, September 2021, MDPI AG

    Docent Kutty Selva Nandakumar

  17. Optimization of CAR-T Cell-Based Therapies Using Small-Molecule-Based Safety Switches

    Article • Journal of Medicinal Chemistry, June 2021, American Chemical Society (ACS)

    Docent Kutty Selva Nandakumar

  18. Imidazole Scaffold based Compounds in the Development of Therapeutic Drugs

    Article • Current Topics in Medicinal Chemistry, May 2021, Bentham Science Publishers

    Docent Kutty Selva Nandakumar

  19. Design, Synthesis, and Structure–Activity Relationship of N-Aryl-N′-(thiophen-2-yl)thiourea Derivatives as Novel and Specific Human TLR1/2 Agonists for Potential Cancer Immunotherapy

    Article • Journal of Medicinal Chemistry, May 2021, American Chemical Society (ACS)

    Docent Kutty Selva Nandakumar

  20. Comparative Analysis on Abnormal Methylome of Differentially Expressed Genes and Disease Pathways in the Immune Cells of RA and SLE

    Article • Frontiers in Immunology, May 2021, Frontiers

    Docent Kutty Selva Nandakumar

  21. Polymorphic estrogen receptor binding site causes CD2-dependent sex bias in the susceptibility to autoimmune diseases

    Article • April 2021, Research Square

    Docent Kutty Selva Nandakumar

  22. ‘SMASH’ recommendations for standardised microscopic arthritis scoring of histological sections from inflammatory arthritis animal models

    Article • Annals of the Rheumatic Diseases, February 2021, BMJ

    Docent Kutty Selva Nandakumar

  23. Targeted inhibition of ATP5B gene prevents bone erosion in collagen-induced arthritis by inhibiting osteoclastogenesis

    Article • Pharmacological Research, January 2021, Elsevier

    Docent Kutty Selva Nandakumar

  24. Emerging and state of the art hemagglutinin-targeted influenza virus inhibitors

    Article • Expert Opinion on Pharmacotherapy, December 2020, Taylor & Francis

    Docent Kutty Selva Nandakumar

  25. Structural Insights into the Atomistic Mechanisms of Uric Acid Recognition and Translocation of Human Urate Anion Transporter 1

    Article • ACS Omega, December 2020, American Chemical Society (ACS)

    Docent Kutty Selva Nandakumar

  26. Design and pharmaceutical applications of proteolysis-targeting chimeric molecules

    Article • Biochemical Pharmacology, December 2020, Elsevier

    Docent Kutty Selva Nandakumar

  27. Gancao Nurish-Yin Decoction Ameliorates Imiquimod-Induced Psoriasis-Like Skin Lesions and Inflammation in Mice

    Article • December 2020, Research Square

    Docent Kutty Selva Nandakumar

  28. Genetic dissection of a major haplotype associated with arthritis reveal FcγR2b and FcγR3 to act additively

    Article • European Journal of Immunology, November 2020, Wiley

    Docent Kutty Selva Nandakumar, Professor Mark Cragg

  29. Collagen-induced inflammations

    Article • November 2020, Cold Spring Harbor Laboratory Press

    Docent Kutty Selva Nandakumar

  30. Potential treatment methods targeting 2019-nCoV infection

    Article • European Journal of Medicinal Chemistry, November 2020, Elsevier

    Docent Kutty Selva Nandakumar

  31. Vitamin D3 receptor polymorphisms regulate T cells and T cell-dependent inflammatory diseases

    Article • Proceedings of the National Academy of Sciences, September 2020, Proceedings of the National Academy of Sciences

    Docent Kutty Selva Nandakumar, Rikard Holmdahl

  32. Recent Research on Flavonoids and their Biomedical applications

    Article • Current Medicinal Chemistry, July 2020, Bentham Science Publishers

    Docent Kutty Selva Nandakumar

  33. Phytoestrogens protect joints in collagen induced arthritis by increasing IgG glycosylation and reducing osteoclast activation

    Article • International Immunopharmacology, June 2020, Elsevier

    Docent Kutty Selva Nandakumar

  34. Cartilage-binding antibodies initiate joint inflammation and promote chronic erosive arthritis

    Article • May 2020, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  35. Metformin, AMPK activator inhibits activation of fibroblast-like synoviocytes but promotes hyaluronan and proteoglycan link protein 1 secretion

    Article • Molecular Therapy — Methods & Clinical Development, May 2020, Elsevier

    Docent Kutty Selva Nandakumar

  36. SNX10 deficiency restricts foam cell formation and protects against atherosclerosis by suppressing CD36-Lyn axis

    Article • Canadian Journal of Cardiology, May 2020, Elsevier

    Docent Kutty Selva Nandakumar

  37. Molecular and Cellular Pathways Contributing to Joint Damage in Rheumatoid Arthritis

    Article • Mediators of Inflammation, March 2020, Hindawi Publishing Corporation

    Docent Kutty Selva Nandakumar

  38. Adenosine monophosphate-activated protein kinase activator inhibits activation of fibroblast-like synoviocytes but promotes hyaluronan and proteoglycan link protein 1 secretion

    Article • February 2020, Research Square

    Docent Kutty Selva Nandakumar

  39. [1,2,4]Triazolo[1,5-a]pyrimidine derivative (Mol-5) is a new NS5-RdRp inhibitor of DENV2 proliferation and DENV2-induced inflammation

    Article • Acta Pharmacologica Sinica, November 2019, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  40. Autoantibodies as Diagnostic Markers and Mediator of Joint Inflammation in Arthritis

    Article • Mediators of Inflammation, October 2019, Hindawi Publishing Corporation

    Docent Kutty Selva Nandakumar

  41. GLP-1 Receptor Activation Abrogates β-Cell Dysfunction by PKA Cα-Mediated Degradation of Thioredoxin Interacting Protein

    Article • Frontiers in Pharmacology, October 2019, Frontiers

    Docent Kutty Selva Nandakumar

  42. Asperosaponin VI protects against bone destructions in collagen induced arthritis by inhibiting osteoclastogenesis

    Article • Phytomedicine, October 2019, Elsevier

    Docent Kutty Selva Nandakumar

  43. Immunotherapy for treating methamphetamine, heroin and cocaine use disorders

    Article • Drug Discovery Today, August 2019, Elsevier

    Docent Kutty Selva Nandakumar

  44. SNX10 (sorting nexin 10) inhibits colorectal cancer initiation and progression by controlling autophagic degradation of SRC

    Article • Autophagy, July 2019, Taylor & Francis

    Docent Kutty Selva Nandakumar

  45. Cartilage-binding antibodies induce pain through immune complex–mediated activation of neurons

    Article • The Journal of Experimental Medicine, June 2019, Rockefeller University Press

    Docent Kutty Selva Nandakumar, Professor Mark Cragg

  46. Protective effects of Wang-Bi tablet on bone destruction in collagen-induced arthritis by regulating osteoclast-osteoblast functions

    Article • Journal of Ethnopharmacology, June 2019, Elsevier

    Docent Kutty Selva Nandakumar

  47. Autophagy induced by STING, an unnoticed and primordial function of cGAS

    Article • Cellular and Molecular Immunology, May 2019, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  48. Regulatory role of Golgi brefeldin A resistance factor‐1 in amyloid precursor protein trafficking, cleavage and Aβ formation

    Article • Journal of Cellular Biochemistry, May 2019, Wiley

    Docent Kutty Selva Nandakumar

  49. Therapeutic effects of artesunate on lupus-prone MRL/lpr mice are dependent on T follicular helper cell differentiation and activation of JAK2-STAT3 Signaling Pathway

    Article • Phytomedicine, May 2019, Elsevier

    Docent Kutty Selva Nandakumar

  50. Analysis of data from breast diseases treated with 5-alpha reductase inhibitors for benign prostatic hyperplasia

    Article • Clinical Breast Cancer, April 2019, Elsevier

    Docent Kutty Selva Nandakumar

  51. TLR1/2 Specific Small‐Molecule Agonist Suppresses Leukemia Cancer Cell Growth by Stimulating Cytotoxic T Lymphocytes

    Article • Advanced Science, March 2019, Wiley

    Docent Kutty Selva Nandakumar

  52. The autoantibody response to cyclic citrullinated collagen type II peptides in rheumatoid arthritis

    Article • Rheumatology, March 2019, Oxford University Press (OUP)

    Docent Kutty Selva Nandakumar

  53. Nanobiocatalysts for Industrial Applications

    Article • January 2019, Elsevier

    Docent Kutty Selva Nandakumar

  54. Large expert-curated database for benchmarking document

    Article • Database, January 2019, Oxford University Press (OUP)

    Dr Daniel Prieto, Dr James A.L. Brown, Professor Amanda G Thrift, Docent Kutty Selva Nandakumar, Professor Miguel Viveiros, MD Diego A. Valera-Cornejo, Dr Soroush Safaei, Dr Carmen San Martín, Piero Carninci, Dr Florian Rehfeldt, Dr Yoichi Watanabe, Kazuki Ide, Mr Alvin Wong, Dr Adrian Meule, Dr Maurizio Petrelli, Dr Christine McGarrigle, Dr Tristan Reddan, Dr Nicola Roberts, Professor Stefan Lorkowski, Dr Cyrille Goarant, Dr Emma C Hobbs, Dr. Saurab Sharma, Ph.D., Dr Farid Rahimi, Prof. Iseult Lynch, Mirella Walker, Dr Luca Galluzzi, Sophie Ohlsson, Professor Tullio Florio, Dr Rabea A Gadelkareem, Dr Azubuike Christian Ukubuiwe, Prof Gajendra PS Raghava, Prof Jun Shen

  55. Streptococcal Endo-β-N-Acetylglucosaminidase Suppresses Antibody-Mediated Inflammation In Vivo

    Article • Frontiers in Immunology, July 2018, Frontiers

    Docent Kutty Selva Nandakumar

  56. Antigen-Specific Tolerization and Targeted Delivery as Therapeutic Strategies for Autoimmune Diseases

    Article • Trends in Biotechnology, July 2018, Elsevier

    Docent Kutty Selva Nandakumar

  57. Chronic Active Arthritis Driven by Macrophages Without Involvement of T Cells

    Article • Arthritis & Rheumatology, June 2018, Wiley

    Docent Kutty Selva Nandakumar, Dr Cecilia Fahlquist-Hagert, Rikard Holmdahl

  58. Q63, a novel DENV2 RdRp non-nucleoside inhibitor, inhibited DENV2 replication and infection

    Article • Journal of Pharmacological Sciences, June 2018, Elsevier

    Docent Kutty Selva Nandakumar

  59. Recent advances in the development of vaccines for chronic inflammatory autoimmune diseases

    Article • Vaccine, May 2018, Elsevier

    Docent Kutty Selva Nandakumar

  60. A Shared Epitope of Collagen Type XI and Type II Is Recognized by Pathogenic Antibodies in Mice and Humans with Arthritis

    Article • Frontiers in Immunology, April 2018, Frontiers

    Docent Kutty Selva Nandakumar

  61. Increased salt exposure affects both lymphoid and myeloid effector functions, influencing innate-associated disease but not T-cell-associated autoimmunity

    Article • Immunology, April 2018, Wiley

    Docent Kutty Selva Nandakumar, Rikard Holmdahl

  62. A Restricted Role for FcγR in the Regulation of Adaptive Immunity

    Article • The Journal of Immunology, March 2018, The American Association of Immunologists

    Docent Kutty Selva Nandakumar

  63. Tatanan A from the Acorus calamus L . root inhibited dengue virus proliferation and infections

    Article • Phytomedicine, March 2018, Elsevier

    Docent Kutty Selva Nandakumar

  64. Targeting IgG in Arthritis: Disease Pathways and Therapeutic Avenues

    Article • International Journal of Molecular Sciences, February 2018, MDPI AG

    Docent Kutty Selva Nandakumar

  65. An update on smart biocatalysts for industrial and biomedical applications

    Article • Journal of The Royal Society Interface, February 2018, Royal Society Publishing

    Docent Kutty Selva Nandakumar

  66. Inhibition of dengue viral infection by diasarone-I is associated with 2'O methyltransferase of NS5

    Article • European Journal of Pharmacology, February 2018, Elsevier

    Docent Kutty Selva Nandakumar

  67. Germinal Center B Cells Are Essential for Collagen-Induced Arthritis

    Article • Arthritis & Rheumatology, January 2018, Wiley

    Docent Kutty Selva Nandakumar, Rikard Holmdahl

  68. Targeting pattern-recognition receptors to discover new small molecule immune modulators

    Article • European Journal of Medicinal Chemistry, January 2018, Elsevier

    Docent Kutty Selva Nandakumar

  69. Biomaterials for Induction and Treatment of Autoimmunity

    Article • January 2017, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  70. Regulation of autoantibody activity by the IL-23–TH17 axis determines the onset of autoimmune disease

    Article • Nature Immunology, November 2016, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  71. Animal Models of Rheumatoid Arthritis (I): Pristane-Induced Arthritis in the Rat

    Article • PLoS ONE, May 2016, PLOS

    Docent Kutty Selva Nandakumar

  72. Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism

    Article • Annals of the Rheumatic Diseases, November 2015, BMJ

    Docent Kutty Selva Nandakumar

  73. Macrophage-derived reactive oxygen species protects against autoimmune priming with a defined polymeric adjuvant

    Article • Immunology, November 2015, Wiley

    Docent Kutty Selva Nandakumar

  74. System A amino acid transporters regulate glutamine uptake and attenuate antibody-mediated arthritis

    Article • Immunology, October 2015, Wiley

    Docent Kutty Selva Nandakumar, Rikard Holmdahl

  75. B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production

    Article • European Journal of Immunology, June 2015, Wiley

    Docent Kutty Selva Nandakumar, Rikard Holmdahl

  76. Reactive Oxygen Species in Psoriasis and Psoriasis Arthritis: Relevance to Human Disease

    Article • International Archives of Allergy and Immunology, January 2015, Karger Publishers

    Docent Kutty Selva Nandakumar

  77. Nerve Conduction Velocity Is Regulated by the Inositol Polyphosphate-4-Phosphatase II Gene

    Article • American Journal Of Pathology, September 2014, Elsevier

    Docent Kutty Selva Nandakumar

  78. Mannan induces ROS-regulated, IL-17A–dependent psoriasis arthritis-like disease in mice

    Article • Proceedings of the National Academy of Sciences, August 2014, Proceedings of the National Academy of Sciences

    Docent Kutty Selva Nandakumar

  79. Synthetic Polymer as an Adjuvant in Collagen‐Induced Arthritis

    Article • Current Protocols in Mouse Biology, March 2014, Wiley

    Docent Kutty Selva Nandakumar

  80. A Single Functional Group Substitution in C5a Breaks B Cell and T Cell Tolerance and Protects Against Experimental Arthritis

    Article • Arthritis & Rheumatology, February 2014, Wiley

    Docent Kutty Selva Nandakumar, Rikard Holmdahl

  81. Epitope-specific antibody response is controlled by immunoglobulin VHpolymorphisms

    Article • The Journal of Experimental Medicine, February 2014, Rockefeller University Press

    Docent Kutty Selva Nandakumar

  82. Chemical cross-linking abrogates adjuvant potential of natural polymers

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Docent Kutty Selva Nandakumar

  83. Affinity purified anti-citrullinated protein/peptide antibodies target antigens expressed in the rheumatoid joint

    Article • Arthritis Research & Therapy, January 2014, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  84. Type II collagen antibody response is enriched in the synovial fluid of rheumatoid joints and directed to the same major epitopes as in collagen induced arthritis in primates and mice

    Article • Arthritis Research & Therapy, January 2014, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  85. Polymeric cryogels are biocompatible, and their biodegradation is independent of oxidative radicals

    Article • Journal of Biomedical Materials Research Part A, October 2013, Wiley

    Docent Kutty Selva Nandakumar

  86. Stimuli‐Responsive Polymers as Adjuvants and Carriers for Antigen Delivery

    Article • October 2013, Wiley

    Docent Kutty Selva Nandakumar

  87. Incomplete B Cell Tolerance to Cartilage Oligomeric Matrix Protein in Mice

    Article • Arthritis & Rheumatism, August 2013, Wiley

    Docent Kutty Selva Nandakumar

  88. Characterization of chemically defined poly-N-isopropylacrylamide based copolymeric adjuvants

    Article • Vaccine, August 2013, Elsevier

    Docent Kutty Selva Nandakumar

  89. Dominant suppression of inflammation by glycan-hydrolyzed IgG

    Article • Proceedings of the National Academy of Sciences, May 2013, Proceedings of the National Academy of Sciences

    Docent Kutty Selva Nandakumar

  90. Type II collagen–specific antibodies induce cartilage damage in mice independent of inflammation

    Article • Arthritis & Rheumatism, February 2013, Wiley

    Docent Kutty Selva Nandakumar

  91. Collagen antibody–induced arthritis evokes persistent pain with spinal glial involvement and transient prostaglandin dependency

    Article • Arthritis & Rheumatism, November 2012, Wiley

    Docent Kutty Selva Nandakumar

  92. Applications of polymeric adjuvants in studying autoimmune responses and vaccination against infectious diseases

    Article • Journal of The Royal Society Interface, November 2012, Royal Society Publishing

    Docent Kutty Selva Nandakumar

  93. Genetic control of antibody production during collagen‐induced arthritis development in heterogeneous stock mice

    Article • Arthritis & Rheumatism, October 2012, Wiley

    Docent Kutty Selva Nandakumar

  94. C57BL/6 mice need MHC class II Aq to develop collagen-induced arthritis dependent on autoreactive T cells

    Article • Annals of the Rheumatic Diseases, October 2012, BMJ

    Docent Kutty Selva Nandakumar

  95. Correction: Pathogenic Autoreactive B Cells Are Not Negatively Selected toward Matrix Protein Collagen II

    Article • The Journal of Immunology, September 2012, The American Association of Immunologists

    Docent Kutty Selva Nandakumar

  96. Keratinocyte growth factor (KGF) delays the onset of collagen-induced arthritis

    Article • Autoimmunity, September 2012, Taylor & Francis

    Docent Kutty Selva Nandakumar

  97. Enhancement of Antibody-Induced Arthritis via Toll-Like Receptor 2 Stimulation Is Regulated by Granulocyte Reactive Oxygen Species

    Article • American Journal Of Pathology, July 2012, Elsevier

    Docent Kutty Selva Nandakumar

  98. Antibody‐Mediated Arthritis and New Therapeutic Avenues

    Article • April 2012, Wiley

    Docent Kutty Selva Nandakumar

  99. Genetic control of antibody production during collagen induced arthritis development in heterogeneous stock mice

    Article • Annals of the Rheumatic Diseases, February 2012, BMJ

    Docent Kutty Selva Nandakumar

  100. Identification of arthritis promoting non-obese diabetic genes in theCia9locus using different genetic strategies

    Article • Annals of the Rheumatic Diseases, February 2012, BMJ

    Docent Kutty Selva Nandakumar

  101. Collagen Antibody-Induced Arthritis: A Disease-Relevant Model for Studies of Persistent Joint Pain

    Article • January 2012, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  102. Cartilage oligomeric matrix protein specific antibodies are pathogenic

    Article • Arthritis Research & Therapy, January 2012, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  103. Crystal structure of an arthritogenic anticollagen immune complex

    Article • Arthritis & Rheumatism, November 2011, Wiley

    Docent Kutty Selva Nandakumar

  104. Collagen Type II and a Thermo-Responsive Polymer of N-Isopropylacrylamide Induce Arthritis Independent of Toll-Like Receptors

    Article • American Journal Of Pathology, November 2011, Elsevier

    Docent Kutty Selva Nandakumar

  105. Pathogenic Autoreactive B Cells Are Not Negatively Selected toward Matrix Protein Collagen II

    Article • The Journal of Immunology, September 2011, The American Association of Immunologists

    Docent Kutty Selva Nandakumar

  106. Inhibiting the C5–C5a receptor axis

    Article • Molecular Immunology, August 2011, Elsevier

    Docent Kutty Selva Nandakumar

  107. An encephalomyelitis-specific locus on chromosome 16 in mouse controls disease development and expression of immune-regulatory genes

    Article • Journal of Neuroimmunology, June 2011, Elsevier

    Docent Kutty Selva Nandakumar

  108. A dominant suppressive MHC class II haplotype interacting with autosomal genes controls autoantibody production and chronicity of arthritis

    Article • Annals of the Rheumatic Diseases, May 2011, BMJ

    Docent Kutty Selva Nandakumar

  109. High-resolution mapping of a complex disease, a model for rheumatoid arthritis, using heterogeneous stock mice

    Article • Human Molecular Genetics, May 2011, Oxford University Press (OUP)

    Docent Kutty Selva Nandakumar

  110. Adjuvant properties of a biocompatible thermo-responsive polymer of N-isopropylacrylamide in autoimmunity and arthritis

    Article • Journal of The Royal Society Interface, May 2011, Royal Society Publishing

    Docent Kutty Selva Nandakumar

  111. Effects of oestradiol and raloxifene on the induction and effector phases of experimental postmenopausal arthritis and secondary osteoporosis

    Article • Clinical & Experimental Immunology, April 2011, Wiley

    Docent Kutty Selva Nandakumar

  112. Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chronic arthritis development

    Article • March 2011, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  113. Collagen antibody-induced arthritis (CAIA) evokes transient inflammation but persistent allodynia

    Article • Annals of the Rheumatic Diseases, February 2011, BMJ

    Docent Kutty Selva Nandakumar

  114. Correction: A Recombinant Vaccine Effectively Induces C5a-Specific Neutralizing Antibodies and Prevents Arthritis

    Article • PLoS ONE, January 2011, PLOS

    Docent Kutty Selva Nandakumar

  115. Chemical changes demonstrated in cartilage by synchrotron infrared microspectroscopy in an antibody-induced murine model of rheumatoid arthritis

    Article • Journal of Biomedical Optics, January 2011, SPIE

    Docent Kutty Selva Nandakumar

  116. Heterogeneous Stock Mice are Susceptible to Encephalomyelitis and Antibody-initiated Arthritis but not to Collagen- and G6PI-induced Arthritis

    Article • Scandinavian Journal of Immunology, December 2010, Wiley

    Docent Kutty Selva Nandakumar

  117. Specific antibody protection of the extracellular cartilage matrix against collagen antibody–induced damage

    Article • Arthritis & Rheumatism, October 2010, Wiley

    Docent Kutty Selva Nandakumar

  118. A Recombinant Vaccine Effectively Induces C5a-Specific Neutralizing Antibodies and Prevents Arthritis

    Article • PLoS ONE, October 2010, PLOS

    Docent Kutty Selva Nandakumar

  119. Pain mechanisms in animal models of rheumatoid arthritis

    Article • Scandinavian Journal of Pain, July 2010, De Gruyter

    Docent Kutty Selva Nandakumar

  120. Rabeximod reduces arthritis severity in mice by decreasing activation of inflammatory cells

    Article • Annals of the Rheumatic Diseases, June 2010, BMJ

    Docent Kutty Selva Nandakumar

  121. Antibodies to citrullinated proteins: molecular interactions and arthritogenicity

    Article • Immunological Reviews, December 2009, Wiley

    Docent Kutty Selva Nandakumar

  122. In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012

    Article • Free Radical Biology and Medicine, September 2009, Elsevier

    Docent Kutty Selva Nandakumar

  123. Secretory lysosome targeting and induced secretion of human soluble TNF-α receptor in murine hematopoietic cells in vivo as a principle for immunoregulation in inflammation and malignancy

    Article • Experimental Hematology, August 2009, Elsevier

    Docent Kutty Selva Nandakumar

  124. Pathogenic antibody recognition of cartilage

    Article • Cell and Tissue Research, June 2009, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  125. Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis

    Article • The Journal of Experimental Medicine, February 2009, Rockefeller University Press

    Docent Kutty Selva Nandakumar

  126. The role of collagen antibodies in mediating arthritis

    Article • Modern Rheumatology, October 2008, Oxford University Press (OUP)

    Docent Kutty Selva Nandakumar

  127. Three‐dimensional culture for monoclonal antibody production by hybridoma cells immobilized in macroporous gel particles

    Article • Biotechnology Progress, September 2008, Wiley

    Docent Kutty Selva Nandakumar

  128. Role of anti-hinge antibodies in therapeutic cleavage of IgG: response to Drs. Lutz and Fumia

    Article • Trends in Immunology, August 2008, Elsevier

    Docent Kutty Selva Nandakumar

  129. C4b-binding protein (C4BP) inhibits development of experimental arthritis in mice

    Article • Annals of the Rheumatic Diseases, July 2008, BMJ

    Docent Kutty Selva Nandakumar

  130. The novel small molecule drug Rabeximod is effective in reducing disease severity of mouse models of autoimmune disorders

    Article • Annals of the Rheumatic Diseases, July 2008, BMJ

    Docent Kutty Selva Nandakumar

  131. Diagnosis of typhoid fever: detection of Salmonella typhi porins-specific antibodies by inhibition ELISA

    Article • Clinical & Experimental Immunology, June 2008, Oxford University Press (OUP)

    Docent Kutty Selva Nandakumar

  132. Cartilage oligomeric matrix protein induction of chronic arthritis in mice

    Article • Arthritis & Rheumatism, June 2008, Wiley

    Docent Kutty Selva Nandakumar

  133. The role of collagen antibodies in mediating arthritis

    Article • Modern Rheumatology, June 2008, Oxford University Press (OUP)

    Docent Kutty Selva Nandakumar

  134. Therapeutic cleavage of IgG: new avenues for treating inflammation

    Article • Trends in Immunology, April 2008, Elsevier

    Docent Kutty Selva Nandakumar

  135. The crystal structure of the pathogenic collagen type II-specific mouse monoclonal antibody CIIC1 Fab: Structure to function analysis

    Article • Molecular Immunology, April 2008, Elsevier

    Docent Kutty Selva Nandakumar

  136. Cartilage oligomeric matrix protein deficiency promotes early onset and the chronic development of collagen-induced arthritis

    Article • Arthritis Research & Therapy, January 2008, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  137. Arthritogenic antibodies specific for a major type II collagen triple‐helical epitope bind and destabilize cartilage independent of inflammation

    Article • Arthritis & Rheumatism, December 2007, Wiley

    Docent Kutty Selva Nandakumar

  138. Macrophages suppress T cell responses and arthritis development in mice by producing reactive oxygen species

    Article • Journal of Clinical Investigation, October 2007, American Society for Clinical Investigation

    Docent Kutty Selva Nandakumar

  139. Blocking of experimental arthritis by cleavage of IgG antibodies in vivo

    Article • Arthritis & Rheumatism, September 2007, Wiley

    Docent Kutty Selva Nandakumar

  140. Endoglycosidase treatment abrogates IgG arthritogenicity: Importance of IgG glycosylation in arthritis

    Article • European Journal of Immunology, September 2007, Wiley

    Docent Kutty Selva Nandakumar

  141. Monoclonal Antibody Production Using a New Supermacroporous Cryogel Bioreactor

    Article • Biotechnology Progress, August 2007, Wiley

    Docent Kutty Selva Nandakumar

  142. Ethanol prevents development of destructive arthritis

    Article • Proceedings of the National Academy of Sciences, January 2007, Proceedings of the National Academy of Sciences

    Docent Kutty Selva Nandakumar

  143. Collagen Antibody Induced Arthritis

    Article • January 2007, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  144. Monoclonal Antibody Production Using a New Supermacroporous Cryogel Bioreactor

    Article • Biotechnology Progress, January 2007, Wiley

    Docent Kutty Selva Nandakumar

  145. Backcross and Partial Advanced Intercross Analysis of Nonobese Diabetic Gene-Mediated Effects on Collagen-Induced Arthritis Reveals an Interactive Effect by Two Major Loci

    Article • The Journal of Immunology, September 2006, The American Association of Immunologists

    Docent Kutty Selva Nandakumar

  146. Do “infectious” prey select for high levels of natural antibodies in tropical pythons?

    Article • Evolutionary Ecology, August 2006, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  147. Arthritis induced with cartilage‐specific antibodiesis IL‐4‐dependent

    Article • European Journal of Immunology, May 2006, Wiley

    Docent Kutty Selva Nandakumar

  148. Therapeutic Vaccination of Active Arthritis with a Glycosylated Collagen Type II Peptide in Complex with MHC Class II Molecules

    Article • The Journal of Immunology, January 2006, The American Association of Immunologists

    Docent Kutty Selva Nandakumar

  149. Integrated bioprocess for the production and isolation of urokinase from animal cell culture using supermacroporous cryogel matrices

    Article • Biotechnology and Bioengineering, January 2006, Wiley

    Docent Kutty Selva Nandakumar

  150. Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity

    Article • Arthritis Research & Therapy, January 2006, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  151. Article • Arthritis Research & Therapy, January 2006, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  152. Article • Arthritis Research & Therapy, January 2006, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  153. Stromal cells and osteoclasts are responsible for exacerbated collagen‐induced arthritis in interferon‐β–deficient mice

    Article • Arthritis & Rheumatism, November 2005, Wiley

    Docent Kutty Selva Nandakumar

  154. Efficient promotion of collagen antibody induced arthritis (CAIA) using four monoclonal antibodies specific for the major epitopes recognized in both collagen induced arthritis and rheumatoid arthritis

    Article • Journal of Immunological Methods, September 2005, Elsevier

    Docent Kutty Selva Nandakumar

  155. Arthritogenic anti–type II collagen antibodies are pathogenic for cartilage‐derived chondrocytes independent of inflammatory cells

    Article • Arthritis & Rheumatism, June 2005, Wiley

    Docent Kutty Selva Nandakumar

  156. Methotrexate ameliorates T cell dependent autoimmune arthritis and encephalomyelitis but not antibody induced or fibroblast induced arthritis

    Article • Annals of the Rheumatic Diseases, April 2005, BMJ

    Docent Kutty Selva Nandakumar

  157. A genetic contamination in MHC‐congenic mouse strains reveals a locus on chromosome 10 that determines autoimmunity and arthritis susceptibility

    Article • European Journal of Immunology, March 2005, Wiley

    Docent Kutty Selva Nandakumar

  158. The Plasminogen Activator/Plasmin System Is Essential for Development of the Joint Inflammatory Phase of Collagen Type II-Induced Arthritis

    Article • American Journal Of Pathology, March 2005, Elsevier

    Docent Kutty Selva Nandakumar

  159. Identification of epistasis through a partial advanced intercross reveals three arthritis loci within the Cia5 QTL in mice

    Article • Genes & Immunity, February 2005, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  160. Article • Arthritis Research & Therapy, January 2005, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  161. Article • Arthritis Research & Therapy, January 2005, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  162. Affinity binding of cells to cryogel adsorbents with immobilized specific ligands: effect of ligand coupling and matrix architecture

    Article • Journal of Molecular Recognition, September 2004, Wiley

    Docent Kutty Selva Nandakumar

  163. Antileukoproteinase: Modulation of neutrophil function and therapeutic effects on anti–type II collagen antibody–induced arthritis

    Article • Arthritis & Rheumatism, July 2004, Wiley

    Docent Kutty Selva Nandakumar

  164. Two monoclonal antibodies to precisely the same epitope of type II collagen select non-crossreactive phage clones by phage display: implications for autoimmunity and molecular mimicry

    Article • Molecular Immunology, June 2004, Elsevier

    Docent Kutty Selva Nandakumar

  165. Complement activation by both classical and alternative pathways is critical for the effector phase of arthritis

    Article • European Journal of Immunology, March 2004, Wiley

    Docent Kutty Selva Nandakumar

  166. Relapsing Polychondritis, Induced in Mice with Matrilin 1, Is an Antibody- and Complement-Dependent Disease

    Article • American Journal Of Pathology, March 2004, Elsevier

    Docent Kutty Selva Nandakumar

  167. Article • Arthritis Research, January 2004, Springer Science + Business Media

    Docent Kutty Selva Nandakumar

  168. Collagen Type II-Specific Monoclonal Antibody-Induced Arthritis in Mice

    Article • American Journal Of Pathology, November 2003, Elsevier

    Docent Kutty Selva Nandakumar

  169. Genetic Control of Tolerance to Type II Collagen and Development of Arthritis in an Autologous Collagen-Induced Arthritis Model

    Article • The Journal of Immunology, September 2003, The American Association of Immunologists

    Docent Kutty Selva Nandakumar

  170. Induction of arthritis by single monoclonal IgG anti‐collagen type II antibodies and enhancement of arthritis in mice lacking inhibitory FcγRIIB

    Article • European Journal of Immunology, July 2003, Wiley

    Docent Kutty Selva Nandakumar

  171. IL-4-deficient mice develop less acute but more chronic relapsing collagen-induced arthritis

    Article • European Journal of Immunology, October 2002, Wiley

    Docent Kutty Selva Nandakumar

  172. Epitope‐specific recognition of type II collagen by rheumatoid arthritis antibodies is shared with recognition by antibodies that are arthritogenic in collagen‐induced arthritis in the mouse

    Article • Arthritis & Rheumatism, September 2002, Wiley

    Docent Kutty Selva Nandakumar

  173. Mouse models for rheumatoid arthritis

    Article • Trends in Genetics, June 2002, Elsevier

    Docent Kutty Selva Nandakumar

  174. IL-10-Deficient B10.Q Mice Develop More Severe Collagen-Induced Arthritis, but Are Protected from Arthritis Induced with Anti-Type II Collagen Antibodies

    Article • The Journal of Immunology, September 2001, The American Association of Immunologists

    Docent Kutty Selva Nandakumar

  175. Evaluation of the Percentage of Peripheral T Cells with Two Different T Cell Receptor α-Chains and of their Potential Role in Autoimmunity

    Article • Journal of Autoimmunity, June 2001, Elsevier

    Docent Kutty Selva Nandakumar, Dr Alexandre Corthay

  176. Influence of Immunopotentiators on the Antiporin Immunoglobulin G Subclass: Distribution and Protective Immunity Against Murine Salmonellosis

    Article • Scandinavian Journal of Immunology, August 1999, Wiley

    Docent Kutty Selva Nandakumar

  177. Monoclonal antibodies against Salmonella porins: Generation and characterization

    Article • Immunology Letters, July 1992, Elsevier

    Docent Kutty Selva Nandakumar

  178. Applications of Nanomaterials for Activation and Suppression of Immune Responses

    Article • IGI Global

    Docent Kutty Selva Nandakumar

  179. Applications of Nanomaterials for Activation and Suppression of Immune Responses

    Article • IGI Global

    Docent Kutty Selva Nandakumar