All Stories

  1. Crystal structure of ferric recombinant horseradish peroxidase

    Article • JBIC Journal of Biological Inorganic Chemistry, March 2025, Springer Science + Business Media

    Christine Toelzer

  2. ATAC and SAGA histone acetyltransferase modules facilitate transcription factor binding to nucleosomes independent of their acetylation activity

    Article • Nucleic Acids Research, December 2024, Oxford University Press (OUP)

    Christine Toelzer

  3. Engineering the ADDobody protein scaffold for generation of high-avidity ADDomer super-binders

    Article • Structure, March 2024, Elsevier

    Christine Toelzer

  4. Cryo-EM reveals binding of linoleic acid to SARS-CoV-2 spike glycoprotein, suggesting an antiviral treatment strategy

    Article • Acta Crystallographica Section D Structural Biology, January 2023, International Union of Crystallography

    Christine Toelzer

  5. The free fatty acid–binding pocket is a conserved hallmark in pathogenic β-coronavirus spike proteins from SARS-CoV to Omicron

    Article • Science Advances, November 2022, American Association for the Advancement of Science

    Christine Toelzer

  6. Highly efficient CRISPR-mediated large DNA docking and multiplexed prime editing using a single baculovirus

    Article • Nucleic Acids Research, July 2022, Oxford University Press (OUP)

    Christine Toelzer

  7. Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder-causing mutation

    Article • Nucleic Acids Research, May 2022, Oxford University Press (OUP)

    Christine Toelzer

  8. The Free Fatty Acid-Binding Pocket is a Conserved Hallmark in Pathogenic β-Coronavirus Spike Proteins from SARS-CoV to Omicron

    Article • April 2022, Cold Spring Harbor Laboratory Press

    Christine Toelzer

  9. Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2

    Article • Nature Communications, January 2022, Springer Science + Business Media

    Christine Toelzer

  10. Structural basis for cell-type specific evolution of viral fitness by SARS-CoV-2

    Article • May 2021, Cold Spring Harbor Laboratory Press

    Christine Toelzer

  11. Frontispiz: Molecular Simulations suggest Vitamins, Retinoids and Steroids as Ligands of the Free Fatty Acid Pocket of the SARS‐CoV‐2 Spike Protein

    Article • Angewandte Chemie, March 2021, Wiley

    Christine Toelzer

  12. Molecular Simulations suggest Vitamins, Retinoids and Steroids as Ligands of the Free Fatty Acid Pocket of the SARS‐CoV‐2 Spike Protein**

    Article • Angewandte Chemie, February 2021, Wiley

    Christine Toelzer

  13. Synthesis, biological properties and structural study of new halogenated azolo[4,5-b]pyridines as inhibitors of CK2 kinase

    Article • Bioorganic Chemistry, January 2021, Elsevier

    Christine Toelzer

  14. The MultiBac BEVS: Basics, applications, performance and recent developments

    Article • January 2021, Elsevier

    Christine Toelzer

  15. Expanding the Application Range of Microbial Oxidoreductases by an Alcohol Dehydrogenase from Comamonas testosteroni with a Broad Substrate Spectrum and pH Profile

    Article • Catalysts, November 2020, MDPI AG

    Christine Toelzer

  16. Molecular Simulations suggest Vitamins, Retinoids and Steroids as Ligands binding the Free Fatty Acid Pocket of SARS-CoV-2 Spike Protein

    Article • October 2020, American Chemical Society (ACS)

    Christine Toelzer

  17. Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein

    Article • Science, September 2020, American Association for the Advancement of Science

    Christine Toelzer

  18. Baculovirus-vectored precision delivery of large DNA cargoes in human genomes

    Article • August 2020, Cold Spring Harbor Laboratory Press

    Christine Toelzer

  19. Unexpected free fatty acid binding pocket in the cryo-EM structure of SARS-CoV-2 spike protein

    Article • June 2020, Cold Spring Harbor Laboratory Press

    Christine Toelzer

  20. Arabidopsis immunity regulator EDS1 in a PAD4/SAG101-unbound form is a monomer with an inherently inactive conformation

    Article • Journal of Structural Biology, December 2019, Elsevier

    Christine Toelzer

  21. The MultiBac system: a perspective

    Article • Emerging Topics in Life Sciences, September 2019, Portland Press Ltd.

    Christine Toelzer

  22. MultiBac: Baculovirus-Mediated Multigene DNA Cargo Delivery in Insect and Mammalian Cells

    Article • Viruses, February 2019, MDPI AG

    Christine Toelzer

  23. Large expert-curated database for benchmarking document

    Article • Database, January 2019, Oxford University Press (OUP)

    Dr Daniel Prieto, Associate Professor James A.L. Brown, Professor Amanda G Thrift, Docent Kutty Selva Nandakumar, Professor Miguel Viveiros, MD Diego A. Valera-Cornejo, Dr Soroush Safaei, Dr Carmen San Martín, Piero Carninci, Dr Florian Rehfeldt, Dr Yoichi Watanabe, Kazuki Ide, Mr Alvin Wong, PD Dr. Adrian Meule, Dr Maurizio Petrelli, Dr Christine McGarrigle, Dr Tristan Reddan, Dr Nicola Roberts, Professor Stefan Lorkowski, Dr Cyrille Goarant, Dr Emma C Hobbs, Dr. Saurab Sharma, Ph.D., Dr Farid Rahimi, Prof. Iseult Lynch, Mirella Walker, Dr Luca Galluzzi, Sophie Ohlsson, Professor Tullio Florio, Dr Rabea A Gadelkareem, Dr Azubuike Christian Ukubuiwe, Prof Gajendra PS Raghava, Prof Jun Shen, Lubna Razak, ABHISHEKA BANSAL, Craig Billington, Dr Alejandro Lazo-Langner, Joan Albiol, MOURAD TAYEBI, Chuang Ma, Christine Toelzer , Dr. Kathrin Karsay, Professor Andrew M Beale, Professor Hugh James Byrne, Dr Ugo Marzocchi, Ana Nordberg, Martin Bartas, Natalia Echeverría, Dr Patricia M Graves

  24. Improved protein-crystal identification by using 2,2,2-trichloroethanol as a fluorescence enhancer

    Article • Acta Crystallographica Section F Structural Biology Communications, April 2018, International Union of Crystallography

    Christine Toelzer

  25. Control of Chiral Magnetism Through Electric Fields in Multiferroic Compounds above the Long-Range Multiferroic Transition

    Article • Physical Review Letters, October 2017, American Physical Society (APS)

    Christine Toelzer

  26. A novel esterase subfamily with α/β-hydrolase fold suggested by structures of two bacterial enzymes homologous tol-homoserineO-acetyl transferases

    Article • FEBS Letters, December 2015, Wiley

    Christine Toelzer

  27. Crystallization and preliminary crystallographic analysis ofcgHle, a homoserine acetyltransferase homologue, fromCorynebacterium glutamicum

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, December 2008, International Union of Crystallography

    Christine Toelzer