All Stories

  1. Resolvin D2 prevents vascular remodeling, hypercontractility and endothelial dysfunction in obese hypertensive mice through modulation of vascular and proinflammatory factors

    Article • Biomedicine & Pharmacotherapy, May 2024, Elsevier

    Prof Jesmond Dalli

  2. Resolvin T4 enhances macrophage cholesterol efflux to reduce vascular disease

    Article • Nature Communications, February 2024, Springer Science + Business Media

    Prof Jesmond Dalli

  3. Efferocyte‐Derived MCTRs Metabolically Prime Macrophages for Continual Efferocytosis via Rac1‐Mediated Activation of Glycolysis

    Article • Advanced Science, December 2023, Wiley

    Prof Jesmond Dalli

  4. Reply to: Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples

    Article • Nature Communications, November 2023, Springer Science + Business Media

    Prof Jesmond Dalli

  5. Maresin 1 activates brown adipose tissue and promotes browning of white adipose tissue in mice

    Article • Molecular Metabolism, August 2023, Elsevier

    Prof Jesmond Dalli

  6. Author Correction: A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae

    Article • Nature Communications, July 2023, Springer Science + Business Media

    Prof Jesmond Dalli

  7. Mistakes in the re-analysis of lipidomic data obtained from a human model of resolving inflammation lead to erroneous conclusions

    Article • March 2023, Cold Spring Harbor Laboratory Press

    Prof Jesmond Dalli

  8. Pro-inflammatory and pro-resolving lipid mediators of inflammation in HIV: effect of aspirin intervention

    Article • EBioMedicine, March 2023, Elsevier

    Prof Jesmond Dalli

  9. Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis

    Article • JCI Insight, February 2023, American Society for Clinical Investigation

    Prof Jesmond Dalli

  10. Resolution Pharmacology: Focus on Pro-Resolving Annexin A1 and Lipid Mediators for Therapeutic Innovation in Inflammation

    Article • The Annual Review of Pharmacology and Toxicology, January 2023, Annual Reviews

    Prof Jesmond Dalli

  11. Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans

    Article • Journal of Clinical Investigation, January 2023, American Society for Clinical Investigation

    Prof Jesmond Dalli

  12. Deletion of macrophage Gpr101 disrupts their phenotype and function dysregulating host immune responses in sterile and infectious inflammation

    Article • Biochemical Pharmacology, January 2023, Elsevier

    Prof Jesmond Dalli

  13. Resolvin D2 Attenuates Cardiovascular Damage in Angiotensin II-Induced Hypertension

    Article • Hypertension, January 2023, Wolters Kluwer Health

    Prof Jesmond Dalli

  14. Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis

    Article • JCI Insight, October 2022, American Society for Clinical Investigation

    Prof Jesmond Dalli

  15. Vagus nerve stimulation promotes resolution of inflammation by a mechanism that involves Alox15 and requires the α7nAChR subunit

    Article • Proceedings of the National Academy of Sciences, May 2022, Proceedings of the National Academy of Sciences

    Peder Olofsson, Prof Jesmond Dalli

  16. Distinct immune profiles of HIV‐infected subjects are linked to specific lipid mediator signature

    Article • Immunity Inflammation and Disease, May 2022, Wiley

    Prof Jesmond Dalli

  17. MCTR3 reprograms arthritic monocytes to upregulate Arginase-1 and exert pro-resolving and tissue-protective functions in experimental arthritis

    Article • EBioMedicine, May 2022, Elsevier

    Prof Jesmond Dalli

  18. Evidence for the presence and diagnostic utility of SPM in human peripheral blood

    Article • April 2022, Cold Spring Harbor Laboratory Press

    Prof Jesmond Dalli

  19. Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions

    Article • Progress in Lipid Research, April 2022, Elsevier

    Prof Jesmond Dalli

  20. Utility of the Specialized Pro-Resolving Mediators as Diagnostic and Prognostic Biomarkers in Disease

    Article • Biomolecules, February 2022, MDPI AG

    Prof Jesmond Dalli

  21. Lipid mediator n‐3 docosapentaenoic acid‐derived protectin D1 enhances synaptic inhibition of hippocampal principal neurons by interaction with a G‐protein‐coupled receptor

    Article • The FASEB Journal, February 2022, Wiley

    Prof Jesmond Dalli

  22. 20‐hydroxyeicosatetraenoic acid (20‐HETE) is a pivotal endogenous ligand for TRPV1‐mediated neurogenic inflammation in the skin

    Article • British Journal of Pharmacology, February 2022, Wiley

    Prof Jesmond Dalli

  23. Aspirin activates resolution pathways to reprogram T cell and macrophage responses in colitis-associated colorectal cancer

    Article • Science Advances, February 2022, American Association for the Advancement of Science

    Prof Jesmond Dalli

  24. Lipoxins modulate neutrophil oxidative burst, integrin expression and lymphatic transmigration differentially in human health and atherosclerosis

    Article • The FASEB Journal, February 2022, Wiley

    Prof Jesmond Dalli

  25. Stereoselective Synthesis, Configurational Assignment and Biological Evaluations of the Lipid Mediator RvD2 n‐3 DPA

    Article • Chemistry - A European Journal, December 2021, Wiley

    Prof Jesmond Dalli

  26. Differential Lipid Mediator Involvement in the Different Forms of Genetic Frontotemporal Dementia: Novel Insights into Neuroinflammation

    Article • Journal of Alzheimer s Disease, October 2021, IOS Press

    Prof Jesmond Dalli

  27. Lipid Mediator n-3 Docosapentaenoic Acid-Derived Protectin D1­(PD1n-3DPA) Enhances Synaptic Inhibition of Hippocampal Principal Neurons by Interaction with a G-Protein Coupled Receptor

    Article • September 2021, Research Square

    Prof Jesmond Dalli

  28. Dysregulated Maresin Concentrations in Plasma and Nasal Secretions From Patients With Chronic Rhinosinusitis

    Article • Frontiers in Immunology, August 2021, Frontiers

    Prof Jesmond Dalli

  29. Dysregulated plasma lipid mediator profiles in critically ill COVID-19 patients

    Article • PLoS ONE, August 2021, PLOS

    Prof Jesmond Dalli

  30. Disrupted Resolution Mechanisms Favor Altered Phagocyte Responses in COVID-19

    Article • Circulation Research, August 2021, Wolters Kluwer Health

    Prof Jesmond Dalli

  31. Differential sensitivity of inflammatory macrophages and alternatively activated macrophages to ferroptosis

    Article • European Journal of Immunology, July 2021, Wiley

    Prof Jesmond Dalli

  32. Loss of 15-lipoxygenase disrupts Treg differentiation altering their pro-resolving functions

    Article • Cell Death and Differentiation, May 2021, Springer Science + Business Media

    Prof Jesmond Dalli

  33. 14,17,18-Trihydroxy-Eicosatetraenoic Acid: A Novel Pro-Resolving Lipid Mediator from Marine Microalgae

    Article • ACS Pharmacology & Translational Science, May 2021, American Chemical Society (ACS)

    Prof Jesmond Dalli

  34. Platelets orchestrate the resolution of pulmonary inflammation in mice by T reg cell repositioning and macrophage education

    Article • The Journal of Experimental Medicine, May 2021, Rockefeller University Press

    Prof Jesmond Dalli

  35. Changes in brown adipose tissue lipid mediator signatures with aging, obesity, and DHA supplementation in female mice

    Article • The FASEB Journal, May 2021, Wiley

    Prof Jesmond Dalli

  36. Splenic Nerve Neuromodulation Reduces Inflammation and Promotes Resolution in Chronically Implanted Pigs

    Article • Frontiers in Immunology, March 2021, Frontiers

    Prof Jesmond Dalli

  37. Protective activities of distinct omega-3 enriched oils are linked to their ability to upregulate specialized pro-resolving mediators

    Article • PLoS ONE, December 2020, PLOS

    Prof Jesmond Dalli

  38. HIF1α activation in dendritic cells under sterile conditions promotes an anti-inflammatory phenotype through accumulation of intracellular lipids

    Article • Scientific Reports, November 2020, Springer Science + Business Media

    Prof Jesmond Dalli

  39. Methodologies and Procedures Employed in the Identification and Quantitation of Lipid Mediators via LC-MS/MS

    Article • October 2020, Research Square

    Prof Jesmond Dalli

  40. Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis

    Article • Nature Communications, October 2020, Springer Science + Business Media

    Prof Jesmond Dalli

  41. The GPR40 Agonist GW9508 Enhances Neutrophil Function to Aid Bacterial Clearance During E. coli Infections

    Article • Frontiers in Immunology, September 2020, Frontiers

    Prof Jesmond Dalli

  42. Editorial: Role of Blood Cells in Inflammatory and Vascular Disorders

    Article • Frontiers in Pharmacology, September 2020, Frontiers

    Prof Jesmond Dalli

  43. RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance

    Article • Frontiers in Immunology, September 2020, Frontiers

    Prof Jesmond Dalli

  44. Treatment With a Marine Oil Supplement Alters Lipid Mediators and Leukocyte Phenotype in Healthy Patients and Those With Peripheral Artery Disease

    Article • Journal of the American Heart Association, August 2020, Wolters Kluwer Health

    Prof Jesmond Dalli

  45. ANGPTL3 deficiency alters the lipid profile and metabolism of cultured hepatocytes and human lipoproteins

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, July 2020, Elsevier

    Prof Jesmond Dalli

  46. Imbalance of proresolving lipid mediators in persistent allodynia dissociated from signs of clinical arthritis

    Article • Pain, May 2020, Wolters Kluwer Health

    Prof Jesmond Dalli

  47. Immune Regulatory Mediators in Plasma from Patients With Acute Decompensation Are Associated With 3-Month Mortality

    Article • Clinical Gastroenterology and Hepatology, May 2020, Elsevier

    Prof Jesmond Dalli

  48. A combination of LCPUFA ameliorates airway inflammation in asthmatic mice by promoting pro-resolving effects and reducing adverse effects of EPA

    Article • Mucosal Immunology, May 2020, Elsevier

    Prof Jesmond Dalli

  49. Lipid mediators of inflammation and Resolution in individuals with tuberculosis and tuberculosis-Diabetes

    Article • Prostaglandins & Other Lipid Mediators, April 2020, Elsevier

    Prof Jesmond Dalli

  50. Enzymatic studies with 3-oxa n-3 DPA

    Article • Bioorganic Chemistry, March 2020, Elsevier

    Prof Jesmond Dalli

  51. Plant‐ and Fish‐Derived n‐3 PUFAs Suppress Citrobacter Rodentium –Induced Colonic Inflammation

    Article • Molecular Nutrition & Food Research, February 2020, Wiley

    Prof Jesmond Dalli

  52. Stereoselective synthesis of MaR2n-3 DPA

    Article • Tetrahedron Letters, February 2020, Elsevier

    Prof Jesmond Dalli

  53. Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway

    Article • EMBO Molecular Medicine, January 2020, EMBO

    Prof Jesmond Dalli

  54. Enriched Marine Oil Supplements Increase Peripheral Blood Specialized Pro-Resolving Mediators Concentrations and Reprogram Host Immune Responses

    Article • Circulation Research, January 2020, Wolters Kluwer Health

    Prof Jesmond Dalli

  55. A Single Injection of Docosahexaenoic Acid Induces a Pro-Resolving Lipid Mediator Profile in the Injured Tissue and a Long-Lasting Reduction in Neurological Deficit after Traumatic Brain Injury in Mice

    Article • Journal of Neurotrauma, January 2020, Mary Ann Liebert Inc

    Prof Jesmond Dalli

  56. GPR101 mediates the pro-resolving actions of RvD5n-3 DPA in arthritis and infections

    Article • Journal of Clinical Investigation, December 2019, American Society for Clinical Investigation

    Prof Jesmond Dalli

  57. Addendum: Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1 n −3 DPA

    Article • Chemistry - A European Journal, November 2019, Wiley

    Prof Jesmond Dalli

  58. Proresolving Mediators LXB4 and RvE1 Regulate Inflammation in Stromal Cells from Patients with Shoulder Tendon Tears

    Article • American Journal Of Pathology, November 2019, Elsevier

    Prof Jesmond Dalli

  59. Proresolving mediator profiles in cerebrospinal fluid are linked with disease severity and outcome in adults with tuberculous meningitis

    Article • The FASEB Journal, October 2019, Wiley

    Prof Jesmond Dalli

  60. Polyunsaturated fatty acids modify the extracellular vesicle membranes and increase the production of proresolving lipid mediators of human mesenchymal stromal cells

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, October 2019, Elsevier

    Prof Jesmond Dalli

  61. Synthesis, Structural Confirmation, and Biosynthesis of 22-OH-PD1n-3 DPA

    Article • Molecules, September 2019, MDPI AG

    Prof Jesmond Dalli

  62. Early increase of specialized pro-resolving lipid mediators in patients with ST-elevation myocardial infarction

    Article • EBioMedicine, August 2019, Elsevier

    Prof Jesmond Dalli

  63. Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, August 2019, Elsevier

    Prof Jesmond Dalli

  64. Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis

    Article • JCI Insight, July 2019, American Society for Clinical Investigation

    Prof Jesmond Dalli

  65. 15-Epi-LXA4 and MaR1 counter inflammation in stromal cells from patients with Achilles tendinopathy and rupture

    Article • The FASEB Journal, July 2019, Federation of American Societies For Experimental Biology (FASEB)

    Prof Jesmond Dalli

  66. Tendon cells isolated from patients with persistent shoulder tendinopathy show dysregulated resolution responses

    Article • Translational Sports Medicine, June 2019, Hindawi Publishing Corporation

    Prof Jesmond Dalli

  67. Resolvin D1 Attenuates the Organ Injury Associated With Experimental Hemorrhagic Shock

    Article • Annals of Surgery, June 2019, Wolters Kluwer Health

    Prof Jesmond Dalli

  68. Pro-Resolving Mediator Profiles And 5-Lipoxygenase Activity In Cerebrospinal Fluid Correlate with Disease Severity and Outcome in Adults with Tuberculous Meningitis

    Article • April 2019, Cold Spring Harbor Laboratory Press

    Prof Jesmond Dalli

  69. Proresolving mediators LXB4 and RvE1 regulate inflammation in stromal cells from patients with shoulder tendon tears

    Article • April 2019, Cold Spring Harbor Laboratory Press

    Prof Jesmond Dalli

  70. FRI-109-Increased plasma leukotriene B4 in decompensated cirrhosis associates with disease progression and leads to increased skin window neutrophil infiltration

    Article • Journal of Hepatology, April 2019, Elsevier

    Prof Jesmond Dalli

  71. Leukocytes from obese individuals exhibit an impaired SPM signature

    Article • The FASEB Journal, March 2019, Federation of American Societies For Experimental Biology (FASEB)

    Prof Jesmond Dalli, Joan Claria

  72. Novel n-3 Docosapentaneoic Acid-Derived Pro-resolving Mediators Are Vasculoprotective and Mediate the Actions of Statins in Controlling Inflammation

    Article • January 2019, Springer Science + Business Media

    Prof Jesmond Dalli

  73. Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1 n −3 DPA

    Article • Chemistry - A European Journal, December 2018, Wiley

    Prof Jesmond Dalli

  74. New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration

    Article • Molecular Aspects of Medicine, December 2018, Elsevier

    Prof Jesmond Dalli

  75. ERV1/ChemR23 Signaling Protects Against Atherosclerosis by Modifying Oxidized Low-Density Lipoprotein Uptake and Phagocytosis in Macrophages

    Article • Circulation, October 2018, Wolters Kluwer Health

    Prof Jesmond Dalli

  76. n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis

    Article • Brain, October 2018, Oxford University Press (OUP)

    Prof Jesmond Dalli

  77. Endogenously generated arachidonate-derived ligands for TRPV1 induce cardiac protection in sepsis

    Article • The FASEB Journal, July 2018, Federation of American Societies For Experimental Biology (FASEB)

    Professor Roger Corder, Prof Jesmond Dalli, Jianmin Chen

  78. New maresin conjugates in tissue regeneration pathway counters leukotriene D4–stimulated vascular responses

    Article • The FASEB Journal, July 2018, Federation of American Societies For Experimental Biology (FASEB)

    Charles Serhan, Prof Jesmond Dalli

  79. Identification and structure elucidation of the pro‐resolving mediators provides novel leads for resolution pharmacology

    Article • British Journal of Pharmacology, June 2018, Wiley

    Prof Jesmond Dalli

  80. PDn-3 DPA Pathway Regulates Human Monocyte Differentiation and Macrophage Function

    Article • Cell Chemical Biology, June 2018, Elsevier

    Prof Jesmond Dalli

  81. Albumin Counteracts Immune-Suppressive Effects of Lipid Mediators in Patients With Advanced Liver Disease

    Article • Clinical Gastroenterology and Hepatology, May 2018, Elsevier

    Prof Jesmond Dalli

  82. Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli–driven acute inflammation

    Article • JCI Insight, March 2018, American Society for Clinical Investigation

    Prof Jesmond Dalli

  83. Impaired Production and Diurnal Regulation of Vascular RvD n-3 DPA Increase Systemic Inflammation and Cardiovascular Disease

    Article • Circulation Research, March 2018, Wolters Kluwer Health

    Prof Jesmond Dalli

  84. A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults

    Article • eLife, February 2018, eLife

    Prof Jesmond Dalli

  85. Immunoresolvents signaling molecules at intersection between the brain and immune system

    Article • Current Opinion in Immunology, February 2018, Elsevier

    Prof Jesmond Dalli

  86. Trypanosoma cruzi Produces the Specialized Proresolving Mediators Resolvin D1, Resolvin D5, and Resolvin E2

    Article • Infection and Immunity, January 2018, ASM Journals

    Prof Jesmond Dalli

  87. Lipid Mediator Metabolomics Via LC-MS/MS Profiling and Analysis

    Article • January 2018, Springer Science + Business Media

    Prof Jesmond Dalli

  88. Performance of Mixed Species and Mono-specific Algal Diets for Culture of Larval Western School Prawns, Metapenaeus dalli

    Article • Journal of the World Aquaculture Society, December 2017, Wiley

    Prof Jesmond Dalli

  89. Does promoting resolution instead of inhibiting inflammation represent the new paradigm in treating infections?

    Article • Molecular Aspects of Medicine, December 2017, Elsevier

    Prof Jesmond Dalli

  90. Resolvins suppress tumor growth and enhance cancer therapy

    Article • The Journal of Experimental Medicine, November 2017, Rockefeller University Press

    Prof Jesmond Dalli

  91. Pro-Resolving Mediators in Regulating and Conferring Macrophage Function

    Article • Frontiers in Immunology, November 2017, Frontiers

    Prof Jesmond Dalli

  92. The novel lipid mediator PD1n-3 DPA: An overview of the structural elucidation, synthesis, biosynthesis and bioactions

    Article • Prostaglandins & Other Lipid Mediators, November 2017, Elsevier

    Prof Jesmond Dalli

  93. Prolonged immune alteration following resolution of acute inflammation in humans

    Article • PLoS ONE, October 2017, PLOS

    Prof Jesmond Dalli

  94. NLRP3 Inflammasome Deficiency Protects against Microbial Sepsis via Increased Lipoxin B4 Synthesis

    Article • American Review of Respiratory Disease, September 2017, American Thoracic Society

    Prof Jesmond Dalli

  95. Increased 15-PGDH expression leads to dysregulated resolution responses in stromal cells from patients with chronic tendinopathy

    Article • Scientific Reports, September 2017, Springer Science + Business Media

    Prof Jesmond Dalli

  96. Microscale arrays for the profiling of start and stop signals coordinating human-neutrophil swarming

    Article • Nature Biomedical Engineering, June 2017, Springer Science + Business Media

    Prof Jesmond Dalli

  97. Recent advances in the chemistry and biology of anti-inflammatory and specialized pro-resolving mediators biosynthesized from n-3 docosapentaenoic acid

    Article • Bioorganic & Medicinal Chemistry Letters, June 2017, Elsevier

    Prof Jesmond Dalli

  98. 13-Series resolvins mediate the leukocyte-platelet actions of atorvastatin and pravastatin in inflammatory arthritis

    Article • The FASEB Journal, May 2017, Federation of American Societies For Experimental Biology (FASEB)

    Prof Jesmond Dalli

  99. Characterizing the anti-inflammatory and tissue protective actions of a novel Annexin A1 peptide

    Article • PLoS ONE, April 2017, PLOS

    Prof Jesmond Dalli

  100. Protectin D1 n-3 DPA and resolvin D5 n-3 DPA are effectors of intestinal protection

    Article • Proceedings of the National Academy of Sciences, March 2017, Proceedings of the National Academy of Sciences

    Prof Jesmond Dalli

  101. Resolving inflammation by using nutrition therapy

    Article • Current Opinion in Clinical Nutrition & Metabolic Care, March 2017, Wolters Kluwer Health

    Prof Jesmond Dalli

  102. Neutrophil Resolvin E1 Receptor Expression and Function in Type 2 Diabetes

    Article • The Journal of Immunology, January 2017, The American Association of Immunologists

    Prof Jesmond Dalli

  103. Immune resolution mechanisms in inflammatory arthritis

    Article • Nature Reviews Rheumatology, January 2017, Springer Science + Business Media

    Prof Jesmond Dalli

  104. Human Sepsis Eicosanoid and Proresolving Lipid Mediator Temporal Profiles

    Article • Critical Care Medicine, January 2017, Wolters Kluwer Health

    Prof Jesmond Dalli

  105. Vagal Regulation of Group 3 Innate Lymphoid Cells and the Immunoresolvent PCTR1 Controls Infection Resolution

    Article • Immunity, January 2017, Elsevier

    Prof Jesmond Dalli

  106. Plasma lipid mediator (LM) profiling identifies hyper- and hypo-activated groups of patients with ACLF and targeted 20% human albumin solution infusion recalibrates abnormalities

    Article • Journal of Hepatology, January 2017, Elsevier

    Prof Jesmond Dalli

  107. Stereocontrolled synthesis and investigation of the biosynthetic transformations of 16(S),17(S)-epoxy-PDn-3 DPA

    Article • Organic & Biomolecular Chemistry, January 2017, Royal Society of Chemistry

    Prof Jesmond Dalli

  108. Identification and Actions of the Maresin 1 Metabolome in Infectious Inflammation

    Article • The Journal of Immunology, December 2016, The American Association of Immunologists

    Prof Jesmond Dalli

  109. Carbon Monoxide Improves Efficacy of Mesenchymal Stromal Cells During Sepsis by Production of Specialized Proresolving Lipid Mediators*

    Article • Critical Care Medicine, December 2016, Wolters Kluwer Health

    Prof Jesmond Dalli

  110. Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans

    Article • Journal of Clinical Investigation, November 2016, American Society for Clinical Investigation

    Professor Fulvio D'Acquisto, Prof Jesmond Dalli

  111. Synthesis of 13(R)-Hydroxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins

    Article • Journal of Natural Products, October 2016, American Chemical Society (ACS)

    Prof Jesmond Dalli

  112. Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages

    Article • Proceedings of the National Academy of Sciences, October 2016, Proceedings of the National Academy of Sciences

    Professor Nicos A. Petasis, Prof Jesmond Dalli

  113. Signaling and Immunoresolving Actions of Resolvin D1 in Inflamed Human Visceral Adipose Tissue

    Article • The Journal of Immunology, September 2016, The American Association of Immunologists

    Prof Jesmond Dalli

  114. Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation

    Article • The Journal of Immunology, September 2016, The American Association of Immunologists

    Prof Jesmond Dalli

  115. Aspirin-triggered resolvin D1 is produced during self-resolving gram-negative bacterial pneumonia and regulates host immune responses for the resolution of lung inflammation

    Article • Mucosal Immunology, September 2016, Elsevier

    Prof Jesmond Dalli

  116. Proresolving lipid mediators resolvin D1, resolvin D2, and maresin 1 are critical in modulating T cell responses

    Article • Science Translational Medicine, August 2016, American Association for the Advancement of Science

    Prof Jesmond Dalli

  117. Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia

    Article • American Journal Of Pathology, July 2016, Elsevier

    Professor Nicos A. Petasis, Prof Jesmond Dalli

  118. Macrophage Proresolving Mediators—the When and Where

    Article • Microbiology Spectrum, May 2016, ASM Journals

    Prof Jesmond Dalli

  119. Human milk proresolving mediators stimulate resolution of acute inflammation

    Article • Mucosal Immunology, May 2016, Elsevier

    Prof Jesmond Dalli

  120. SPM in CAD and clot remodeling

    Article • The FASEB Journal, April 2016, Federation of American Societies For Experimental Biology (FASEB)

    Prof Jesmond Dalli, Charles Serhan

  121. Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis

    Article • JCI Insight, April 2016, American Society for Clinical Investigation

    Prof Jesmond Dalli

  122. Lipid mediators and the resolution of chronic inflammation: implications for arthritis therapy

    Article • Osteoarthritis and Cartilage, April 2016, Elsevier

    Prof Jesmond Dalli

  123. The Protectin PCTR1 Is Produced by Human M2 Macrophages and Enhances Resolution of Infectious Inflammation

    Article • American Journal Of Pathology, April 2016, Elsevier

    Prof Jesmond Dalli

  124. Identification and Actions of a Novel Third Maresin Conjugate in Tissue Regeneration: MCTR3

    Article • PLoS ONE, February 2016, PLOS

    Prof Jesmond Dalli

  125. Resolvin D4 stereoassignment and its novel actions in host protection and bacterial clearance

    Article • Scientific Reports, January 2016, Nature

    Professor Nicos A. Petasis, Prof Jesmond Dalli

  126. Selective identification of specialized pro-resolving lipid mediators from their biosynthetic double di-oxygenation isomers

    Article • RSC Advances, January 2016, Royal Society of Chemistry

    Prof Jesmond Dalli

  127. Specialized Pro-Resolving Mediators from Omega-3 Fatty Acids Improve Amyloid-β Phagocytosis and Regulate Inflammation in Patients with Minor Cognitive Impairment

    Article • Journal of Alzheimer s Disease, December 2015, IOS Press

    Prof Jesmond Dalli

  128. Maresin 1 Biosynthesis and Proresolving Anti-infective Functions with Human-Localized Aggressive Periodontitis Leukocytes

    Article • Infection and Immunity, December 2015, ASM Journals

    Charles Serhan, Prof Jesmond Dalli

  129. Human Periodontal Stem Cells Release Specialized Proresolving Mediators and Carry Immunomodulatory and Prohealing Properties Regulated by Lipoxins

    Article • Stem Cells Translational Medicine, November 2015, Wiley

    Prof Jesmond Dalli

  130. Synthesis of the 16S,17S-Epoxyprotectin Intermediate in the Biosynthesis of Protectins by Human Macrophages

    Article • Journal of Natural Products, November 2015, American Chemical Society (ACS)

    Prof Jesmond Dalli

  131. Resolvins attenuate inflammation and promote resolution in cigarette smoke-exposed human macrophages

    Article • AJP Lung Cellular and Molecular Physiology, October 2015, American Physiological Society

    Prof Jesmond Dalli

  132. Specialized Pro-Resolving Mediators from Omega-3 Fatty Acids Improve Amyloid-β Phagocytosis and Regulate Inflammation in Patients with Minor Cognitive Impairment

    Article • Journal of Alzheimer s Disease, September 2015, IOS Press

    Prof Jesmond Dalli

  133. The Regulation of Proresolving Lipid Mediator Profiles in Baboon Pneumonia by Inhaled Carbon Monoxide

    Article • American Journal of Respiratory Cell and Molecular Biology, September 2015, American Thoracic Society

    Prof Jesmond Dalli

  134. Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections

    Article • Nature Reports Stem Cells, August 2015, Springer Science + Business Media

    Prof Jesmond Dalli

  135. Identification of resolvin D2 receptor mediating resolution of infections and organ protection

    Article • The Journal of Experimental Medicine, July 2015, Rockefeller University Press

    Prof Jesmond Dalli

  136. Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function

    Article • Journal of Molecular and Cellular Cardiology, July 2015, Elsevier

    Prof Jesmond Dalli

  137. Lipoxin A4 Attenuates Obesity-Induced Adipose Inflammation and Associated Liver and Kidney Disease

    Article • Cell Metabolism, July 2015, Elsevier

    Prof Jesmond Dalli

  138. A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae

    Article • Nature Communications, June 2015, Springer Science + Business Media

    Prof Jesmond Dalli

  139. Proresolving actions of a new resolvin D1 analog mimetic qualifies as an immunoresolvent

    Article • AJP Lung Cellular and Molecular Physiology, May 2015, American Physiological Society

    Prof Jesmond Dalli

  140. The resolution code of acute inflammation: Novel pro-resolving lipid mediators in resolution

    Article • Seminars in Immunology, May 2015, Elsevier

    Prof Jesmond Dalli

  141. Characterization of the anti-inflammatory properties of NCX 429, a dual-acting compound releasing nitric oxide and naproxen

    Article • Life Sciences, April 2015, Elsevier

    Prof Jesmond Dalli

  142. Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, April 2015, Elsevier

    Prof Jesmond Dalli

  143. Novel proresolving and tissue-regenerative resolvin and protectin sulfido-conjugated pathways

    Article • The FASEB Journal, February 2015, Federation of American Societies For Experimental Biology (FASEB)

    Charles Serhan, Prof Jesmond Dalli

  144. Cutting Edge: Maresin-1 Engages Regulatory T Cells To Limit Type 2 Innate Lymphoid Cell Activation and Promote Resolution of Lung Inflammation

    Article • The Journal of Immunology, December 2014, The American Association of Immunologists

    Professor Nicos A. Petasis, Prof Jesmond Dalli

  145. Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1

    Article • AJP Lung Cellular and Molecular Physiology, November 2014, American Physiological Society

    Prof Jesmond Dalli

  146. Proresolving Nanomedicines Activate Bone Regeneration in Periodontitis

    Article • Journal of Dental Research, November 2014, SAGE Publications

    Prof Jesmond Dalli

  147. Maresin 1 biosynthesis during platelet–neutrophil interactions is organ-protective

    Article • Proceedings of the National Academy of Sciences, November 2014, Proceedings of the National Academy of Sciences

    Professor Nicos A. Petasis, Prof Jesmond Dalli

  148. Lipid Mediators in the Resolution of Inflammation

    Article • Cold Spring Harbor Perspectives in Biology, October 2014, Cold Spring Harbor Laboratory Press

    Prof Jesmond Dalli

  149. Correction: Corrigendum: Novel n-3 Immunoresolvents: Structures and Actions

    Article • Scientific Reports, October 2014, Springer Science + Business Media

    Prof Jesmond Dalli

  150. Identification of 14-series sulfido-conjugated mediators that promote resolution of infection and organ protection

    Article • Proceedings of the National Academy of Sciences, October 2014, Proceedings of the National Academy of Sciences

    Prof Jesmond Dalli

  151. Plasma Metabolomics in Human Pulmonary Tuberculosis Disease: A Pilot Study

    Article • PLoS ONE, October 2014, PLOS

    Prof Jesmond Dalli

  152. Aging Delays Resolution of Acute Inflammation in Mice: Reprogramming the Host Response with Novel Nano-Proresolving Medicines

    Article • The Journal of Immunology, October 2014, The American Association of Immunologists

    Prof Jesmond Dalli

  153. Total Synthesis of the Anti-inflammatory and Pro-resolving Lipid Mediator MaR1n−3 DPAUtilizing an sp3-sp3Negishi Cross-Coupling Reaction

    Article • Chemistry - A European Journal, September 2014, Wiley

    Prof Jesmond Dalli

  154. Synthesis and Anti-inflammatory and Pro-resolving Activities of 22-OH-PD1, a Monohydroxylated Metabolite of Protectin D1

    Article • Journal of Natural Products, September 2014, American Chemical Society (ACS)

    Prof Jesmond Dalli

  155. Total Synthesis of the Anti-inflammatory and Pro-resolving Lipid Mediator MaR1n−3 DPAUtilizing an sp3-sp3Negishi Cross-Coupling Reaction

    Article • Chemistry - A European Journal, September 2014, Wiley

    Prof Jesmond Dalli

  156. Maresin Biosynthesis and Identification of Maresin 2, a New Anti-Inflammatory and Pro-Resolving Mediator from Human Macrophages

    Article • PLoS ONE, July 2014, PLOS

    Prof Jesmond Dalli

  157. Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue

    Article • AJP Cell Physiology, July 2014, American Physiological Society

    Prof Jesmond Dalli

  158. Cutting Edge: Parathyroid Hormone Facilitates Macrophage Efferocytosis in Bone Marrow via Proresolving Mediators Resolvin D1 and Resolvin D2

    Article • The Journal of Immunology, July 2014, The American Association of Immunologists

    Prof Jesmond Dalli

  159. Vagus nerve controls resolution and pro-resolving mediators of inflammation

    Article • The Journal of Experimental Medicine, May 2014, Rockefeller University Press

    Prof Jesmond Dalli

  160. Total Synthesis of the Lipid Mediator PD1n-3 DPA: Configurational Assignments and Anti-inflammatory and Pro-resolving Actions

    Article • Journal of Natural Products, February 2014, American Chemical Society (ACS)

    Prof Jesmond Dalli

  161. Investigational Analysis Reveals a Potential Role for Neutrophils in Giant-Cell Arteritis Disease Progression

    Article • Circulation Research, January 2014, Wolters Kluwer Health

    Prof Jesmond Dalli

  162. Stereoselective synthesis of protectin D1: a potent anti-inflammatory and proresolving lipid mediator

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Prof Jesmond Dalli

  163. Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis

    Article • EMBO Molecular Medicine, December 2013, EMBO

    Prof Jesmond Dalli

  164. Plasticity of Leukocytic Exudates in Resolving Acute Inflammation Is Regulated by MicroRNA and Proresolving Mediators

    Article • Immunity, November 2013, Elsevier

    Prof Jesmond Dalli

  165. Contributions of the Three CYP1 Monooxygenases to Pro-Inflammatory and Inflammation-Resolution Lipid Mediator Pathways

    Article • The Journal of Immunology, September 2013, The American Association of Immunologists

    Prof Jesmond Dalli

  166. Microparticles are novel effectors of immunity

    Article • Current Opinion in Pharmacology, August 2013, Elsevier

    Prof Jesmond Dalli

  167. Heterogeneity in Neutrophil Microparticles Reveals Distinct Proteome and Functional Properties

    Article • Molecular & Cellular Proteomics, August 2013, Elsevier

    Prof Jesmond Dalli, Manuel Mayr

  168. Inhaled Carbon Monoxide Accelerates Resolution of Inflammation via Unique Proresolving Mediator–Heme Oxygenase-1 Circuits

    Article • The Journal of Immunology, June 2013, The American Association of Immunologists

    Prof Jesmond Dalli

  169. Proresolving and Tissue-Protective Actions of Annexin A1–Based Cleavage-Resistant Peptides Are Mediated by Formyl Peptide Receptor 2/Lipoxin A4 Receptor

    Article • The Journal of Immunology, June 2013, The American Association of Immunologists

    Prof Jesmond Dalli

  170. Novel n-3 Immunoresolvents: Structures and Actions

    Article • Scientific Reports, June 2013, Springer Science + Business Media

    Prof Jesmond Dalli

  171. The novel 13 S ,14 S ‐epoxy‐maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A 4 hydrolase (LTA 4 H), and shifts macropha...

    Article • The FASEB Journal, March 2013, Wiley

    Professor Nicos A. Petasis, Prof Jesmond Dalli

  172. Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Potent Immunoresolvents

    Article • Chemistry & Biology, February 2013, Elsevier

    Professor Nicos A. Petasis, Prof Jesmond Dalli

  173. Biphasic Modulation of NOS Expression, Protein and Nitrite Products by Hydroxocobalamin Underlies Its Protective Effect in Endotoxemic Shock: Downstream Regulation of COX-2, IL-1β, TNF-α, IL-6, and HMGB1 Expression

    Article • Mediators of Inflammation, January 2013, Hindawi Publishing Corporation

    Professor Fulvio D'Acquisto, Prof Jesmond Dalli

  174. Gene expression signature-based approach identifies a pro-resolving mechanism of action for histone deacetylase inhibitors

    Article • Cell Death and Differentiation, December 2012, Springer Science + Business Media

    Prof Jesmond Dalli

  175. Microfluidic chambers for monitoring leukocyte trafficking and humanized nano-proresolving medicines interactions

    Article • Proceedings of the National Academy of Sciences, November 2012, Proceedings of the National Academy of Sciences

    Prof Jesmond Dalli

  176. Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC–MS/MS

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, November 2012, Elsevier

    Prof Jesmond Dalli

  177. Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators

    Article • Blood, October 2012, American Society of Hematology

    Prof Jesmond Dalli

  178. Self-Limited versus Delayed Resolution of Acute Inflammation: Temporal Regulation of Pro-Resolving Mediators and MicroRNA

    Article • Scientific Reports, September 2012, Springer Science + Business Media

    Prof Jesmond Dalli

  179. Genetic Ablation of the Fpr1 Gene Confers Protection from Smoking-Induced Lung Emphysema in Mice

    Article • American Journal of Respiratory Cell and Molecular Biology, September 2012, American Thoracic Society

    Prof Jesmond Dalli

  180. Resolvin D1 and Resolvin D2 Govern Local Inflammatory Tone in Obese Fat

    Article • The Journal of Immunology, September 2012, The American Association of Immunologists

    Prof Jesmond Dalli

  181. Resolvin D1 Limits Polymorphonuclear Leukocyte Recruitment to Inflammatory Loci

    Article • Arteriosclerosis Thrombosis and Vascular Biology, August 2012, Wolters Kluwer Health

    Prof Jesmond Dalli

  182. Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages

    Article • Proceedings of the National Academy of Sciences, July 2012, Proceedings of the National Academy of Sciences

    Prof Jesmond Dalli

  183. Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain

    Article • The FASEB Journal, January 2012, Wiley

    Prof Jesmond Dalli

  184. Annexin A1 N-Terminal Derived Peptide Ac2-26 Exerts Chemokinetic Effects on Human Neutrophils

    Article • Frontiers in Pharmacology, January 2012, Frontiers

    Dr Simon McArthur, Prof Jesmond Dalli

  185. Annexin A1 regulates neutrophil clearance by macrophages in the mouse bone marrow

    Article • The FASEB Journal, September 2011, Wiley

    Prof Jesmond Dalli

  186. Evidence for an Anti-Inflammatory Loop Centered on Polymorphonuclear Leukocyte Formyl Peptide Receptor 2/Lipoxin A4 Receptor and Operative in the Inflamed Microvasculature

    Article • The Journal of Immunology, April 2011, The American Association of Immunologists

    Prof Jesmond Dalli

  187. Corrections: Anti-Inflammatory Role of the Murine Formyl-Peptide Receptor 2: Ligand-Specific Effects on Leukocyte Responses and Experimental Inflammation

    Article • The Journal of Immunology, February 2011, The American Association of Immunologists

    Prof Jesmond Dalli

  188. 561 THE CINOD NCX 429 INHIBITS MICROVASCULAR INFLAMMATION THROUGH ITS NO-RELEASING PROPERTIES

    Article • Osteoarthritis and Cartilage, October 2010, Elsevier

    Prof Jesmond Dalli

  189. Downstream Gene Activation of the Receptor ALX by the Agonist Annexin A1

    Article • PLoS ONE, September 2010, PLOS

    Professor Fulvio D'Acquisto, Prof Jesmond Dalli

  190. Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature

    Article • Blood, August 2010, American Society of Hematology

    Professor Fulvio D'Acquisto, Prof Jesmond Dalli

  191. CFTR Inhibition Provokes an Inflammatory Response Associated with an Imbalance of the Annexin A1 Pathway

    Article • American Journal Of Pathology, July 2010, Elsevier

    Prof Jesmond Dalli

  192. FPR2/ALX receptor expression and internalization are critical for lipoxin A4and annexin‐derived peptide‐stimulated phagocytosis

    Article • The FASEB Journal, June 2010, Wiley

    Prof Jesmond Dalli

  193. Anti-Inflammatory Role of the Murine Formyl-Peptide Receptor 2: Ligand-Specific Effects on Leukocyte Responses and Experimental Inflammation

    Article • The Journal of Immunology, March 2010, The American Association of Immunologists

    Prof Jesmond Dalli

  194. Exploiting the Annexin A1 pathway for the development of novel anti‐inflammatory therapeutics

    Article • British Journal of Pharmacology, October 2009, Wiley

    Prof Jesmond Dalli

  195. Functional and Ultrastructural Analysis of Annexin A1 and Its Receptor in Extravasating Neutrophils during Acute Inflammation

    Article • American Journal Of Pathology, January 2009, Elsevier

    Prof Jesmond Dalli

  196. Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles

    Article • Blood, September 2008, American Society of Hematology

    Prof Jesmond Dalli

  197. Activation of the annexin 1 counter-regulatory circuit affords protection in the mouse brain microcirculation

    Article • The FASEB Journal, February 2007, Federation of American Societies For Experimental Biology (FASEB)

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins, Prof Jesmond Dalli