All Stories

  1. Elovanoids are a novel class of homeostatic lipid mediators that protect neural cell integrity upon injury
  2. Elovanoids are novel cell-specific lipid mediators necessary for neuroprotective signaling for photoreceptor cell integrity
  3. Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages
  4. Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia
  5. Resolvin D4 stereoassignment and its novel actions in host protection and bacterial clearance
  6. Component-Selective and Stereocontrolled One-Step Three-Component Reaction among Aldehydes, Amines, and Allenyl Boronic Acids or Allenyl Pinacolboronates
  7. Hippocampal Neuro-Networks and Dendritic Spine Perturbations in Epileptogenesis Are Attenuated by Neuroprotectin D1
  8. Molecular characterization of the boron adducts of the proteasome inhibitor bortezomib with epigallocatechin-3-gallate and related polyphenols
  9. Cutting Edge: Maresin-1 Engages Regulatory T Cells To Limit Type 2 Innate Lymphoid Cell Activation and Promote Resolution of Lung Inflammation
  10. Maresin 1 biosynthesis during platelet–neutrophil interactions is organ-protective
  11. The Resolvin D1 Analogue Controls Maturation of Dendritic Cells and Suppresses Alloimmunity in Corneal Transplantation
  12. Protective Actions of Aspirin-Triggered (17R) Resolvin D1 and Its Analogue, 17R-Hydroxy-19-Para-Fluorophenoxy-Resolvin D1 Methyl Ester, in C5a-Dependent IgG Immune Complex–Induced Inflammation and Lung Injury
  13. Advances in GPCR Modeling Evaluated by the GPCR Dock 2013 Assessment: Meeting New Challenges
  14. Avermectins differentially affect ethanol intake and receptor function: implications for developing new therapeutics for alcohol use disorders
  15. Stereocontrolled Total Synthesis of the Potent Anti-inflammatory and Pro-resolving Lipid Mediator Resolvin D3 and Its Aspirin-Triggered 17 R -Epimer
  16. The novel 13 S ,14 S ‐epoxy‐maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A 4 hydrolase (LTA 4 H), and shifts macropha...
  17. Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Potent Immunoresolvents
  18. Preferential killing of triple-negative breast cancer cells in vitro and in vivo when pharmacological aggravators of endoplasmic reticulum stress are combined with autophagy inhibitors
  19. Inhibition of autophagy and induction of breast cancer cell death by mefloquine, an antimalarial agent
  20. Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment
  21. Interleukin-8 reduces post-surgical lymphedema formation by promoting lymphatic vessel regeneration
  22. Perillyl Alcohol for the Treatment of Temozolomide-Resistant Gliomas
  23. Ivermectin reduces alcohol intake and preference in mice
  24. Novel aspirin-triggered neuroprotectin D1 attenuates cerebral ischemic injury after experimental stroke
  25. Interleukin-8 and its receptor CXCR2 in the tumour microenvironment promote colon cancer growth, progression and metastasis
  26. Ataxin-1 Poly(Q)-induced Proteotoxic Stress and Apoptosis Are Attenuated in Neural Cells by Docosahexaenoic Acid-derived Neuroprotectin D1
  27. Stereocontrolled total synthesis of Neuroprotectin D1/Protectin D1 and its aspirin-triggered stereoisomer
  28. Inhibition of the function of class IIa HDACs by blocking their interaction with MEF2
  29. The CXCR2 Antagonist, SCH-527123, Shows Antitumor Activity and Sensitizes Cells to Oxaliplatin in Preclinical Colon Cancer Models
  30. Neuroinflammation
  31. Lipid Mediators
  32. Noscapine inhibits tumor growth in TMZ-resistant gliomas
  33. Resolvins and Protectins in Inflammation Resolution
  34. Preclinical Development of Novel Anti-Glioma Drugs Targeting the Endoplasmic Reticulum Stress Response
  35. Novel Proresolving Aspirin-Triggered DHA Pathway
  36. Enhancement of photodynamic therapy by 2,5-dimethyl celecoxib, a non-cyclooxygenase-2 inhibitor analog of celecoxib
  37. Discovery and Preclinical Evaluation of a Novel Class of Cytotoxic Propynoic Acid Carbamoyl Methyl Amides (PACMAs)
  38. Glutamatergic Neurons in Rodent Models Respond to Nanoscale Particulate Urban Air Pollutants in Vivo and in Vitro
  39. Synthesis of osmium and ruthenium complexes bearing dimethyl (S,S)-2,2′-(pyridine-2,6-diyl)-bis-(4,5-dihydrooxazol-4-carboxylate) ligand and application to catalytic H/D exchange
  40. Docosahexaenoic Acid-Derived Neuroprotectin D1 Induces Neuronal Survival via Secretase- and PPARγ-Mediated Mechanisms in Alzheimer's Disease Models
  41. Lipoxin A4 and Its Analogue Suppress the Tumor Growth of Transplanted H22 in Mice: The Role of Antiangiogenesis
  42. ChemInform Abstract: Titanium-Carbene Mediated Reactions
  43. ChemInform Abstract: Highly Stereocontrolled One-Step Synthesis of anti-β-Amino Alcohols from Organoboronic Acids, Amines, and α-Hydroxy Aldehydes.
  44. ChemInform Abstract: Regioselective Conversion of Arylboronic Acids to Phenols and Subsequent Coupling to Symmetrical Diaryl Ethers.
  45. Antiangiogenic Activities of 2,5-Dimethyl-Celecoxib on the Tumor Vasculature
  46. Cytotoxic effects of celecoxib on Raji lymphoma cells correlate with aggravated endoplasmic reticulum stress but not with inhibition of cyclooxygenase-2
  47. Resolvin D1 binds human phagocytes with evidence for proresolving receptors
  48. Neuroprotectin D1/protectin D1 stereoselective and specific binding with human retinal pigment epithelial cells and neutrophils
  49. Anti-inflammatory and pro-resolving properties of benzo-lipoxin A4 analogs
  50. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis
  51. Enhanced killing of chemo-resistant breast cancer cells via controlled aggravation of ER stress
  52. ChemInform Abstract: Synthesis of 2H-Chromenes and 1,2-Dihydroquinolines from Aryl Aldehydes, Amines, and Alkenylboron Compounds.
  53. 15-Epi-lipoxin A4Inhibits Myeloperoxidase Signaling and Enhances Resolution of Acute Lung Injury
  54. Synthesis of 2H-chromenes and 1,2-dihydroquinolines from aryl aldehydes, amines, and alkenylboron compounds
  55. Selective Survival Rescue in 15-Lipoxygenase-1-deficient Retinal Pigment Epithelial Cells by the Novel Docosahexaenoic Acid-derived Mediator, Neuroprotectin D1
  56. Activation of Polyisoprenyl Diphosphate Phosphatase 1 Remodels Cellular Presqualene Diphosphate †
  57. Green tea polyphenols block the anticancer effects of bortezomib and other boronic acid-based proteasome inhibitors
  58. Rapid Appearance of Resolvin Precursors in Inflammatory Exudates: Novel Mechanisms in Resolution
  59. Design and synthesis of benzo-lipoxin A4 analogs with enhanced stability and potent anti-inflammatory properties
  60. Aggravated Endoplasmic Reticulum Stress as a Basis for Enhanced Glioblastoma Cell Killing by Bortezomib in Combination with Celecoxib or Its Non-Coxib Analogue, 2,5-Dimethyl-Celecoxib
  61. Celecoxib analogs that lack COX-2 inhibitory function: preclinical development of novel anticancer drugs
  62. ChemInform Abstract: Multicomponent Reactions with Organoboron Compounds
  63. COX-2 inhibition is neither necessary nor sufficient for celecoxib to suppress tumor cell proliferation and focus formation in vitro
  64. Simultaneous lipidomic analysis of three families of bioactive lipid mediators leukotrienes, resolvins, protectins and related hydroxy-fatty acids by liquid chromatography/electrospray ionisation tandem mass spectrometry
  65. Chlorotitanium Triisopropoxide
  66. Aspirin-Triggered Lipoxins Override the Apoptosis-Delaying Action of Serum Amyloid A in Human Neutrophils: A Novel Mechanism for Resolution of Inflammation
  67. Calcium-activated endoplasmic reticulum stress as a major component of tumor cell death induced by 2,5-dimethyl-celecoxib, a non-coxib analogue of celecoxib
  69. Resolvin D1, protectin D1, and related docosahexaenoic acid-derived products: Analysis via electrospray/low energy tandem mass spectrometry based on spectra and fragmentation mechanisms
  70. Expanding Roles for Organoboron Compounds – Versatile and Valuable Molecules for Synthetic, Biological and Medicinal Chemistry
  71. Titanium Carbene Mediated Reactions
  72. Metabolic Inactivation of Resolvin E1 and Stabilization of Its Anti-inflammatory Actions
  73. Methyltitanium Triisopropoxide
  74. Regulation of phosphatidylinositol 3–kinase by polyisoprenyl phosphates in neutrophil-mediated tissue injury
  75. Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes.
  76. Anti-Inflammatory Actions of Neuroprotectin D1/Protectin D1 and Its Natural Stereoisomers: Assignments of Dihydroxy-Containing Docosatrienes
  77. Identification of endogenous resolvin E1 and other lipid mediators derived from eicosapentaenoic acid via electrospray low-energy tandem mass spectrometry: spectra and fragmentation mechanisms
  78. RvE1 protects from local inflammation and osteoclastmediated bone destruction in periodontitis
  79. Multitarget inhibition of drug-resistant multiple myeloma cell lines by dimethyl-celecoxib (DMC), a non-COX-2 inhibitory analog of celecoxib
  80. Dimethyl celecoxib as a novel non–cyclooxygenase 2 therapy in the treatment of non–small cell lung cancer
  81. Novel polyisoprenyl phosphates block phospholipase D and human neutrophil activation in vitro and murine peritoneal inflammation in vivo
  82. Multicomponent Reactions with Organoboron Compounds
  83. Design, synthesis and bioactions of novel stable mimetics of lipoxins and aspirin-triggered lipoxins
  84. Cystic fibrosis and lipoxins
  85. Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis
  86. Dimethyl-Celecoxib (DMC), a derivative of celecoxib that lacks cyclooxygenase-2-Inhibitory function, potently mimics the anti-tumor effects of celecoxib on burkitt’s lymphoma in vitro and in vivo
  87. Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1
  88. Interactions Between Lipoxin A4, the Stable Analogue 16-phenoxy-lipoxin A4 and Leukotriene B4 in Cytokine Generation by Human Monocytes
  89. ipso -Nitration of Arylboronic Acids with Chlorotrimethylsilane−Nitrate Salts
  90. Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway
  91. Reduced Inflammation and Tissue Damage in Transgenic Rabbits Overexpressing 15-Lipoxygenase and Endogenous Anti-inflammatory Lipid Mediators
  92. Aspirin-Triggered Lipoxin A4 and B4 Analogs Block Extracellular Signal-Regulated Kinase-Dependent TNF-  Secretion from Human T Cells
  93. Lipoxin A4 and Aspirin-Triggered 15-epi-Lipoxin A4 Inhibit Human Neutrophil Migration: Comparisons Between Synthetic 15 Epimers in Chemotaxis and Transmigration with Microvessel Endothelial Cells and Epithelial Cells
  94. Lipoxins, Aspirin-Triggered Epi-Lipoxins, Lipoxin Stable Analogues, and the Resolution of Inflammation: Stimulation of Macrophage Phagocytosis of Apoptotic Neutrophils In Vivo
  95. Lipoxin A 4 and aspirin-triggered 15-epi-lipoxin A 4 inhibit peroxynitrite formation, NF-κB and AP-1 activation, and IL-8 gene expression in human leukocytes
  96. 15-Epi-16-(Para-Fluorophenoxy)-Lipoxin A4-Methyl Ester, a Synthetic Analogue of 15-epi-Lipoxin A4, Is Protective in Experimental Ischemic Acute Renal Failure
  97. Lipoxins Induce Actin Reorganization in Monocytes and Macrophages But Not in Neutrophils
  98. Stereoselective Synthesis of a nti -α-(Difluoromethyl)-β-amino Alcohols by Boronic Acid Based Three-Component Condensation. Stereoselective Preparation of (2 S ,3 R )-Difluorothreonine
  99. Lipoxin A4 and Aspirin-Triggered 15-Epi-Lipoxin A4 Antagonize TNF- -Stimulated Neutrophil-Enterocyte Interactions In Vitro and Attenuate TNF- -Induced Chemokine Release and Colonocyte Apoptosis in Human Intestinal Mucosa Ex Vivo
  100. ChemInform Abstract: One-Step Three-Component Reaction Among Organoboronic Acids, Amines and Salicylaldehydes.
  101. Bis(cyclopentadienyl)dimethyltitanium
  102. Chlorotitanium Triisopropoxide
  103. Methyltitanium Trichloride
  104. Methyltitanium Triisopropoxide
  105. Methyltitanium Tris(diethylamide)
  106. Dichlorotitanium Diisopropoxide
  107. Bis(cyclopentadienyl)diphenyltitanium
  108. Allyltitanium Triphenoxide
  109. Dibromomethane-Zinc-Titanium(IV) Chloride
  110. ChemInform Abstract: Synthesis of Piperazinones and Benzopiperazinones from 1,2-Diamines and Organoboronic Acids.
  111. ChemInform Abstract: A Facile Stereocontrolled Synthesis of anti-α-(Trifluoromethyl)-β-amino Alcohols.
  112. ChemInform Abstract: Considered Electrophilic Aromatic Substitution. Part 66. Regioselective Nitration of Arylboronic Acids.
  113. Regioselective Conversion of Arylboronic Acids to Phenols and Subsequent Coupling to Symmetrical Diaryl Ethers
  114. One-step three-component reaction among organoboronic acids, amines and salicylaldehydes
  115. Synthesis of piperazinones and benzopiperazinones from 1,2-diamines and organoboronic acids
  116. Fluorophores Related to the Green Fluorescent Protein and Their Use in Optoelectronic Devices
  117. A Facile Stereocontrolled Synthesis of anti -α-(Trifluoromethyl)-β-amino Alcohols
  118. Lipoxin A 4 Analogues Inhibit Leukocyte Recruitment to Porphyromonas gingivalis :  A Role for Cyclooxygenase-2 and Lipoxins in Periodontal Disease †
  119. Cutting Edge: Lipoxins Rapidly Stimulate Nonphlogistic Phagocytosis of Apoptotic Neutrophils by Monocyte-Derived Macrophages
  120. Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitmentin vivo
  121. Lipoxin (LX)A 4 and Aspirin-triggered 15-epi-LXA 4 Inhibit Tumor Necrosis Factor 1α–initiated Neutrophil Responses and Trafficking: Regulators of a Cytokine–Chemokine Axis
  122. Highly Stereocontrolled One-Step Synthesis of anti -β-Amino Alcohols from Organoboronic Acids, Amines, and α-Hydroxy Aldehydes
  123. Irish society of gastroenterology
  124. Irish society of gastroenterology
  125. Pathogen-induced chemokine secretion from model intestinal epithelium is inhibited by lipoxin A4 analogs.
  126. Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues.
  127. Mild Preparation of Haloarenes by Ipso -Substitution of Arylboronic Acids with N -Halosuccinimides
  128. A new synthesis of α-arylglycines from aryl boronic acids
  129. Polyisoprenyl phosphates in intracellular signalling
  130. Lipoxin A4stable analogs inhibit leukocyte rolling and adherence in the rat mesenteric microvasculature: Role of P-selectin
  131. Aspirin-triggered 15-Epi-Lipoxin A 4 (LXA 4 ) and LXA 4 Stable Analogues Are Potent Inhibitors of Acute Inflammation: Evidence for Anti-inflammatory Receptors
  132. Facile Preparation of Fluorine-containing Alkenes, Amides and Alcohols via the Electrophilic Fluorination of Alkenyl Boronic Acids and Trifluoroborates
  133. Lipoxin A4 Stable Analogs Are Potent Mimetics That Stimulate Human Monocytes and THP-1 Cells via a G-protein-linked Lipoxin A4 Receptor
  134. Allenation of Carbonyl Compounds with Alkenyltitanocene Derivatives
  135. A New and Practical Synthesis of α-Amino Acids from Alkenyl Boronic Acids
  136. Formation of eight-membered ring β-keto lactones via the intramolecular trapping of hydroxy acylketenes
  137. Synthesis of Substituted Benzonorbornadienes from Cyclobutenediones
  138. Stereocontrolled synthesis of substituted tetrahydropyrans from 1,3-dioxan-4-ones
  139. Mild conversion of alkenyl boronic acids to alkenyl halides with halosuccinimides
  140. Design of Lipoxin A4 Stable Analogs That Block Transmigration and Adhesion of Human Neutrophils
  141. Titanium-mediated olefinations of cyclobutenedione derivatives
  142. New Stereocontrolled Synthesis of Substituted Tetrahydrofurans from 1,3-Dioxolan-4-ones
  143. Tris(trimethylsilyl) titanacyclobutene: A new mild reagent for the conversion of carbonyls to alkenyl silanes
  144. Methylenations of heteroatom-substituted carbonyls with dimethyl titanocene
  145. Spectroscopic, crystallographic and computational studies of the formation and isomerization of cyclic acetals and ketals of pentonolactones
  146. Reactions of dimethyltitanocene with alkynes and nitriles
  147. Ring-opening metathesis polymerization of norbornene with titanium alkylidenes generated by thermolysis of dimethyltitanocene and related cyclopentadienyltitanium(IV) derivatives
  148. Alicyclic claisen rearrangement with a two-atom ring contraction. A new synthetic approach to cembranoids
  149. Biscyclopropyl titanocene: A novel reagent for the synthesis of alkylidene and vinyl cyclopropanes
  150. The boronic acid mannich reaction: A new method for the synthesis of geometrically pure allylamines
  151. Investigations of the formation of cyclic acetal and ketal derivatives of D-ribono-1,4-lactone and 2-deoxy-D-ribono-1,4-lactone
  152. Enolates of .alpha.-allenyl ketones: formation and aldol reactions of cumulenolates
  153. The synthesis of carbocyclic eight-membered rings
  154. Titanium-mediated carbonyl olefinations. 2. Benzylidenations of carbonyl compounds with dibenzyl titanocene
  155. Titanium-Mediated Carbonyl Olefinations; 3: Conversion of Carbonyl Compounds to Vinylsilanes with Cyclopentadienyl(trimethylsilylmethyl)titanium(IV) Derivatives
  156. Lipoxins and Related Eicosanoids: Biosynthesis, Biological Properties, and Chemical Synthesis
  157. Lipoxine und verwandte Eicosanoide: Biosynthese, biologische Eigenschaften und chemische Synthese
  158. Titanium-mediated carbonyl olefinations. 1. Methylenations of carbonyl compounds with dimethyltitanocene
  159. Synthesis of 8-membered ring lactones from dioxolenones
  160. A claisen rearrangement strategy for the three-atom ring expansion of cyclic ketones. A total synthesis of (±) precapnelladiene
  161. Modulation of leukotriene synthesis and actions by synthetic derivatives of arachidonic acid
  162. N-phenylselenophthalimide (NPSP)
  163. Ethanoarachidonic acids. A new class of arachidonic acid cascade modulators. 1. Monoethano compounds
  164. Ethanoarachidonic acids, a new class of arachidonic acid cascade modulators. 2. Polyethano compounds
  165. The endiandric acid cascade. Electrocyclizations in organic synthesis. I. Stepwise, stereocontrolled total synthesis of endiandric acids A and B
  166. The endiandric acid cascade. Electrocyclizations in organic synthesis. 2. Stepwise, stereocontrolled total synthesis of endiandric acids C-G
  167. The endiandric acid cascade. Electrocyclizations in organic synthesis. 3. "Biomimetic" approach to endiandric acids A-G. Synthesis of precursors
  168. The endiandric acid cascade. Electrocyclizations in organic synthesis. 4. Biomimetic approach to endiandric acids A-G. Total synthesis and thermal studies
  169. Selective inhibition of 5-lipoxygenase by 5,6-methanoleukotriene A4 , a stable analogue of leukotriene A4
  170. 5,6-Methanoleukotriene A4. A stable and biologically active analogue of leukotriene A4
  171. Synthesis of macrocycles by intramolecular ketophosphonate reactions. Stereoselective construction of the "left-wing" of carbomycin B and a synthesis of dl-muscone from oleic acid
  172. Titanium–Carbene Mediated Reactions
  173. Titanium—Carbene Mediated Reactions