All Stories

  1. The Occlusal Contact Area Is Associated with the Magnitude but Not Peak Timing of Changes in Chewing-Induced Brain Blood Flow in Mandibular Prognathism

    Article • Dentistry Journal, June 2025, MDPI AG

    Hiroyuki Kanzaki

  2. Age-Related Changes in Children's Oral Functions: From Early Development to Young Adulthood

    Article • Clinical and Experimental Dental Research, November 2024, Wiley

    Hiroyuki Kanzaki

  3. Antioxidant regulator Nrf2 helps prevent abnormal tissue calcification by controlling ENPP1 protein

    Article • Antioxidants, July 2024, MDPI AG

    Hiroyuki Kanzaki

  4. Jaw Misalignment Reduces Brain Blood Flow During Chewing: New Insights from Dental Research

    Article • Dentistry Journal, May 2024, MDPI AG

    Hiroyuki Kanzaki

  5. Myo-inositol supplement boosts jaw growth in rabbits, potential therapy for small jaws

    Article • Dentistry Journal, February 2024, MDPI AG

    Hiroyuki Kanzaki

  6. Dental X-rays may predict risk of aortic calcification before symptoms appear

    Article • Scientific Reports, October 2023, Springer Science + Business Media

    Hiroyuki Kanzaki

  7. Severe malocclusion linked to reduced oral function in adults: A case-control study

    Article • Clinical and Investigative Orthodontics, October 2023, Taylor & Francis

    Hiroyuki Kanzaki

  8. Soluble Sema4D cleaved from osteoclast precursors by TACE suppresses osteoblastogenesis

    Article • Journal of Cellular and Molecular Medicine, May 2023, Wiley

    Hiroyuki Kanzaki

  9. Bach1 inhibitors reduce bone loss by blocking osteoclast formation

    Article • Frontiers in Cell and Developmental Biology, August 2020, Frontiers

    Hiroyuki Kanzaki

  10. In vivo delivery of an exogenous molecule into murine T lymphocytes using a lymphatic drug delivery system combined with sonoporation

    Article • Biochemical and Biophysical Research Communications, May 2020, Elsevier

    Hiroyuki Kanzaki

  11. Sustained Release of Catechin from Gelatin and Its Effect on Bone Formation in Critical Sized Defects in Rat Calvaria

    Article • Journal of Hard Tissue Biology, January 2020, Society for Hard Tissue Regenerative Biology

    Hiroyuki Kanzaki

  12. Jaw misalignment linked to reduced brain blood flow during chewing

    Article • Scientific Reports, December 2019, Springer Science + Business Media

    Hiroyuki Kanzaki

  13. Nrf2 in bone cells blocks inflammation signals to prevent bone loss

    Article • Bone Reports, December 2019, Elsevier

    Hiroyuki Kanzaki

  14. MicroRNA-3198 Controls Bone Loss During Tooth Movement by Regulating OPG Levels

    Article • BMC Molecular and Cell Biology, April 2019, Springer Science + Business Media

    Hiroyuki Kanzaki

  15. Nutritional supplementation with myo-inositol in growing mice specifically augments mandibular endochondral growth

    Article • Bone, April 2019, Elsevier

    Hiroyuki Kanzaki

  16. EGCG-gelatin slows tooth movement in braces by reducing bone breakdown and inflammation

    Article • Polymers, December 2018, MDPI AG

    Hiroyuki Kanzaki

  17. Orthodontic treatment of acquired open bite accompanied with extreme mesially inclined mandibular molars

    Article • International Orthodontics, December 2018, Elsevier

    Hiroyuki Kanzaki

  18. Traitement orthodontique de la béance acquise associée à une mésioversion très prononcée des molaires mandibulaires

    Article • International Orthodontics, December 2018, Elsevier

    Hiroyuki Kanzaki

  19. Author's response

    Article • American Journal of Orthodontics and Dentofacial Orthopedics, October 2018, Elsevier

    Hiroyuki Kanzaki

  20. Compression and Tension Inversely Change Osteoprotegerin Expression via miR-3198 in Periodontal Ligament Cells

    Article • July 2018, MDPI AG

    Hiroyuki Kanzaki

  21. HMGB1 protein helps regulate tooth movement during orthodontic treatment

    Article • Journal of Oral Biosciences, June 2018, Elsevier

    Hiroyuki Kanzaki

  22. Antibacterial, Hydrophilic Effect and Mechanical Properties of Orthodontic Resin Coated with UV-Responsive Photocatalyst

    Article • Materials, May 2018, MDPI AG

    Hiroyuki Kanzaki

  23. Discovery of Asporin's Role in Jaw Joint Growth and Cartilage Protection

    Article • Bone Reports, December 2017, Elsevier

    Hiroyuki Kanzaki

  24. Jaw growth boosted on one side by local IGF-1 injection: Potential fix for facial asymmetry in mice

    Article • American Journal of Orthodontics and Dentofacial Orthopedics, December 2017, Elsevier

    Hiroyuki Kanzaki

  25. Influence of posterior cranial base growth on the therapeutic effect of bite jumping appliance

    Article • Orthodontic Waves, December 2017, Taylor & Francis

    Hiroyuki Kanzaki

  26. Antioxidant Drug Blocks Bone Loss by Reducing Cell Stress Signals

    Article • Journal of Cellular and Molecular Medicine, October 2017, Wiley

    Hiroyuki Kanzaki

  27. Nasopharyngoscopic Analyses through Anterior Maxillary Distraction Osteogenesis for Adolescent Patients With Cleft Palate

    Article • Journal of Craniofacial Surgery, October 2017, Wolters Kluwer Health

    Hiroyuki Kanzaki, Yoshimichi Imai

  28. New Surgery Method Shows Promise for Improving Facial Features in Cleft Lip and Palate Patients

    Article • Journal of Craniofacial Surgery, June 2017, Wolters Kluwer Health

    Hiroyuki Kanzaki, Yoshimichi Imai

  29. Fighting Gum Disease: How Our Body's Natural Defenses Battle Harmful Oxygen Molecules

    Article • Frontiers in Physiology, May 2017, Frontiers

    Hiroyuki Kanzaki

  30. Bacterial lipid from gum disease pathogen promotes bone loss by interfering with cellular fusion

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, May 2017, Elsevier

    Hiroyuki Kanzaki

  31. Tooth Movement Triggers Blood Vessel Growth Through Enzyme Action in Gum Tissue

    Article • Journal of Periodontal Research, April 2017, Wiley

    Hiroyuki Kanzaki

  32. Novel Device Reveals How Cells Respond to Gentle Stretching During Tooth Movement

    Article • Biology Open, March 2017, The Company of Biologists

    Hiroyuki Kanzaki

  33. Bach1 positively controls RANKL-mediated osteoclastogenesis

    Article • The FASEB Journal, November 2016, Federation of American Societies For Experimental Biology (FASEB)

    Hiroyuki Kanzaki

  34. Enzyme TACE from Immune Cells Drives Bone Loss in Gum Disease through RANKL Protein Release

    Article • The Journal of Immunology, October 2016, The American Association of Immunologists

    Hiroyuki Kanzaki

  35. Cancer-linked enzyme ADAM17 breaks down immune system protein that fights tumors

    Article • Scientific Reports, August 2016, Nature

    Hiroyuki Kanzaki

  36. Molecular Control of Bone Cell Formation: How Protective Enzymes Shape Osteoclast Development

    Article • Redox Biology, August 2016, Elsevier

    Hiroyuki Kanzaki

  37. First Molar's Role as Main Chewing Point in Normal and Protruding Lower Jaw Patients

    Article • The Angle Orthodontist, January 2016, The Angle Orthodontist (EH Angle Education & Research Foundation)

    Hiroyuki Kanzaki

  38. Understanding how tooth disuse affects bone formation: TGF-β pathway study in rat model

    Article • Dental Oral and Craniofacial Research, January 2016, Open Access Text Pvt, Ltd.

    Hiroyuki Kanzaki

  39. Delivery of Molecules to the Lymph Node via Lymphatic Vessels Using Ultrasound and Nano/Microbubbles

    Article • Ultrasound in Medicine & Biology, May 2015, Elsevier

    Hiroyuki Kanzaki

  40. Nrf2 Activation: A Novel Approach to Control Orthodontic Tooth Movement and Prevent Relapse

    Article • Journal of Dental Research, March 2015, SAGE Publications

    Hiroyuki Kanzaki

  41. Nuclear Nrf2 Activation by Cell-Permeable Peptide Shows Promise in Preventing Bone Loss

    Article • Free Radical Biology and Medicine, December 2014, Elsevier

    Hiroyuki Kanzaki

  42. The Keap1/Nrf2 protein axis plays a role in osteoclast differentiation by regulating intracellular reactive oxygen species signaling.

    Article • Journal of Biological Chemistry, February 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Hiroyuki Kanzaki

  43. Nrf2/Keap1 Pathway: A Key Regulator of Bone Cell Development Through Oxidative Stress Contro

    Article • Journal of Biological Chemistry, June 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Hiroyuki Kanzaki

  44. HVJ-E/importin-β hybrid vector for overcoming cytoplasmic and nuclear membranes as double barrier for non-viral gene delivery

    Article • Biomedicine & Pharmacotherapy, October 2012, Elsevier

    Hiroyuki Kanzaki

  45. Effects of local osteoprotegerin gene transfection on orthodontic root resorption during retention: an in vivo micro-CT analysis

    Article • Orthodontics and Craniofacial Research, January 2012, Wiley

    Hiroyuki Kanzaki

  46. Inhibition of T-Cell-Mediated and Infection-Induced Periodontal Bone Resorption by TACE Blockade

    Article • January 2012, Springer Science + Business Media

    Hiroyuki Kanzaki

  47. Local osteoprotegerin gene transfer inhibits relapse of orthodontic tooth movement

    Article • American Journal of Orthodontics and Dentofacial Orthopedics, January 2012, Elsevier

    Hiroyuki Kanzaki

  48. Is RANKL shedding involved in immune cell-mediated osteoclastogenesis?

    Article • January 2010, Springer Science + Business Media

    Hiroyuki Kanzaki

  49. Gene transfer approach blocks bone loss in gum disease by targeting key protein pathway

    Article • Journal of Periodontal Research, April 2008, Wiley

    Hiroyuki Kanzaki

  50. Drug Shows Promise in Controlling Tooth Movement During Orthodontic Treatment

    Article • Journal of Dental Research, August 2006, SAGE Publications

    Hiroyuki Kanzaki

  51. Mechanical Forces in Teeth: How Tension Prevents Bone Loss Through Natural Protein Signals

    Article • Journal of Dental Research, May 2006, SAGE Publications

    Hiroyuki Kanzaki

  52. Gene therapy breakthrough accelerates tooth movement during orthodontic treatment

    Article • Gene Therapy, January 2006, Nature

    Hiroyuki Kanzaki

  53. Mechanical Stress Triggers Bone Loss Through Cell Signaling in Periodontal Ligament

    Article • Journal of Bone and Mineral Research, February 2002, Wiley

    Hiroyuki Kanzaki

  54. Dual Control of Bone Cell Formation by Periodontal Ligament: New Insights for gum homeostasis

    Article • Journal of Dental Research, March 2001, SAGE Publications

    Hiroyuki Kanzaki