All Stories

  1. Glucocorticoid-induced Leucine Zipper (GILZ) is a novel secreted protein by intestinal L-cells and is dysregulated during active ulcerative colitis
  2. Immunonutrition in Acute Geriatric Care: Clinical Outcomes, Inflammatory Profiles, and Immune Responses
  3. Impact of endocrine disruptors on peripheral blood mononuclear cells in vitro: role of gender
  4. Differences in the Expression Levels of SARS-CoV-2 Spike Protein in Cells Treated with mRNA-Based COVID-19 Vaccines: A Study on Vaccines from the Real World
  5. Overexpression of Potential Markers of Regulatory and Exhausted CD8+ T Cells in the Peripheral Blood Mononuclear Cells of Patients with B-Acute Lymphoblastic Leukemia
  6. Association of GILZ with MUC2, TLR2, and TLR4 in Inflammatory Bowel Disease
  7. Diagnostic performance of the Bladder EpiCheck methylation test and photodynamic diagnosis-guided cystoscopy in the surveillance of high-risk non-muscle invasive bladder cancer: A single centre, prospective, blinded clinical trial
  8. Validation in an Independent Cohort of MiR-122, MiR-1271, and MiR-15b as Urinary Biomarkers for the Potential Early Diagnosis of Clear Cell Renal Cell Carcinoma
  9. Cardiovascular, neurological, and pulmonary events following vaccination with the BNT162b2, ChAdOx1 nCoV-19, and Ad26.COV2.S vaccines: An analysis of European data
  10. Blood clots and bleeding events following BNT162b2 and ChAdOx1 nCoV-19 vaccine: An analysis of European data
  11. Immune and Nervous Systems Interaction in Endocrine Disruptors Toxicity: The Case of Atrazine
  12. IgG4 induces tolerogenic M2-like macrophages and correlates with disease progression in colon cancer
  13. Detection of urinary miRNAs for diagnosis of clear cell renal cell carcinoma
  14. Immune modulation via T regulatory cell enhancement: disease‐modifying therapies for autoimmunity and their potential for chronic allergic and inflammatory diseases – An EAACI position paper of the Task Force on Immunopharmacology (TIPCO)
  15. Expansion of regulatory T cells prevents type 1 diabetes onset by inhibiting islet destruction
  16. Identification of 15 T Cell Restricted Genes Evaluates T Cell Infiltration of Human Healthy Tissues and Cancers and Shows Prognostic and Predictive Potential
  17. Evaluation of potential targets for ADCC induction against regulatory T cells in renal cell carcinoma
  18. The antibody frequently used to stain human GITR, does not bind GITR, leading to misleading results.
  19. The first‐generation phosphodiesterase 5 inhibitors and their pharmacokinetic issue
  20. ENGINEERED ALGINATE MICROCAPSULES FOR MOLECULAR THERAPY TROUGH BIOLOGIC SECRETING CELLS
  21. Context-Dependent Effect of Glucocorticoids on the Proliferation, Differentiation, and Apoptosis of Regulatory T Cells: A Review of the Empirical Evidence and Clinical Applications
  22. Beta-carotene, telomerase activity and Alzheimer’s disease in old age subjects
  23. Telomeres Increasingly Develop Aberrant Structures in Aging Humans
  24. Comparing biologicals and small molecule drug therapies for chronic respiratory diseases
  25. GITR is an interesting target for immunotherapy of cancers, infection and autoimmune diseases
  26. Triggering of GITR expands a subset of regulatory T cells and prevents diabetes development in mice
  27. Use of regulatory T cells to treat autoimmune diseases and prevent GVHD in murine models and humans
  28. Regulatory T cells (Tregs) expressing specific Treg markers that infiltrate 9 types of human cancers
  29. The Proinflammatory Cytokine GITRL Contributes to TRAIL-mediated Neurotoxicity in the HCN-2 Human Neuronal Cell Line
  30. Influence of chemotherapeutic drug-related gene polymorphisms on toxicity and survival of early breast cancer patients receiving adjuvant chemotherapy
  31. The role of GITR single-positive cells in immune homeostasis
  32. GITR: A Modulator of Regulatory and Effector T-Cell Activity, Crucial in Tumour Rejection and Autoimmune Diseases
  33. Modulation of tumor immunity: a patent evaluation of WO2015026684A1
  34. Are we Able to Harness the Immunomodulatory Power of Cytokines for Novel Autoimmune Disease Treatments?
  35. GITR+ regulatory T cells in the treatment of autoimmune diseases
  36. A focused Real Time PCR strategy to determine GILZ expression in mouse tissues
  37. Glucocorticoid-Induced Tumour Necrosis Factor Receptor-Related Protein: A Key Marker of Functional Regulatory T Cells
  38. The Clinical Pharmacology of Past, Present, and Future Glucocorticoids
  39. The Molecular and Cellular Mechanisms Responsible for the Anti-inflammatory and Immunosuppressive Effects of Glucocorticoids
  40. Expansion of regulatory GITR+CD25low/-CD4+ T cells in systemic lupus erythematosus patients
  41. L-GILZ binds p53 and MDM2 and suppresses tumor growth through p53 activation in human cancer cells
  42. Transcriptional regulation of kinases downstream of the T cell receptor: another immunomodulatory mechanism of glucocorticoids
  43. Eicosapentaenoic Acid Activates RAS/ERK/C/EBPβ Pathway through H-Ras Intron 1 CpG Island Demethylation in U937 Leukemia Cells
  44. Glucocorticoid-Induced Tumor Necrosis Factor Receptor Family-Related Ligand Triggering Upregulates Vascular Cell Adhesion Molecule-1 and Intercellular Adhesion Molecule-1 and Promotes Leukocyte Adhesion
  45. Characterization of a new regulatory CD4+ T cell subset in primary Sjogren's syndrome
  46. L-GILZ forms a complex with p53 and mdm2 and suppresses tumor growth through p53 activation
  47. Expansion of CD4+CD25-GITR+ regulatory T-cell subset in the peripheral blood of patients with primary Sjögren's syndrome: correlation with disease activity
  48. Mechanisms of the anti-inflammatory effects of glucocorticoids: genomic and nongenomic interference with MAPK signaling pathways
  49. The intracellular portion of GITR enhances NGF-promoted neurite growth through an inverse modulation of Erk and NF-κB signalling
  50. Pharmacological modulation of GITRL/GITR system: therapeutic perspectives
  51. CD8+T Cells: GITR Matters
  52. Balance between Regulatory T and Th17 Cells in Systemic Lupus Erythematosus: The Old and the New
  53. GITR Gene Deletion and GITR-Fc Soluble Protein Administration Inhibit Multiple Organ Failure Induced by Zymosan
  54. CD4+CD25lowGITR+ cells: A novel human CD4+ T-cell population with regulatory activity
  55. Eicosapentaenoic Acid Demethylates a Single CpG That Mediates Expression of Tumor Suppressor CCAAT/Enhancer-binding Protein δ in U937 Leukemia Cells
  56. Glucocorticoid-Induced TNFR family Related gene (GITR) enhances dendritic cell activity
  57. The glucocorticoid-induced TNF receptor family-related protein (GITR) is critical to the development of acute pancreatitis in mice
  58. Effect of dietary saturated fatty acids on HNF-4α DNA binding activity and ApoCIII mRNA in sedentary rat liver
  59. Role of regulatory T cells in rheumatoid arthritis: facts and hypothesis
  60. Neutralization of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Reduces Spinal Cord Injury Damage in Mice
  61. Identification of regulatory T cells in systemic lupus erythematosus
  62. GITR: A Modulator of Immune Response and Inflammation
  63. The GITRL–GITR system alters TLR-4 expression on DC during fungal infection
  64. Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity
  65. Glucocorticoid-Induced Tumor Necrosis Factor Receptor-Related (GITR)-Fc Fusion Protein Inhibits GITR Triggering and Protects from the Inflammatory Response after Spinal Cord Injury
  66. Peroxisome Proliferator-Activated Receptor-α Contributes to the Anti-Inflammatory Activity of Glucocorticoids
  67. Glucocorticoid-Induced TNFR-Related Protein Lowers the Threshold of CD28 Costimulation in CD8+ T Cells
  68. Modulation of Acute and Chronic Inflammation of the Lung by GITR and its Ligand
  69. GITR/GITRL: More than an effector T cell co-stimulatory system
  70. Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy
  71. GITR-GITRL System, A Novel Player in Shock and Inflammation
  72. Genetic and pharmacological inhibition of GITR-GITRL interaction reduces chronic lung injury induced by bleomycin instillation
  73. Interaction of CTSD and A2M polymorphisms in the risk for Alzheimer's disease
  74. Modulation of Pro- and Antiapoptotic Molecules in Double-Positive (CD4+CD8+) Thymocytes following Dexamethasone Treatment
  75. Proinflammatory Role of Glucocorticoid-Induced TNF Receptor-Related Gene in Acute Lung Inflammation
  76. Dietary PUFA modulate the expression of proliferation and differentiation markers in Morris 3924A hepatoma cells
  77. The Glucocorticoid-Induced Tumor Necrosis Factor Receptor-Related Gene Modulates the Response to Candida albicans Infection
  78. GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily
  79. Glucocorticoid-induced TNF receptor family gene (GITR) knockout mice exhibit a resistance to splanchnic artery occlusion (SAO) shock
  80. Frontline: GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations
  81. Dietary α-linolenic acid reduces COX-2 expression and induces apoptosis of hepatoma cells
  82. Cathepsin D Polymorphism in Italian Elderly Subjects with Sporadic Late-Onset Alzheimer’s Disease
  83. Enhanced expression of hepatic lipogenic enzymes in an animal model of sedentariness
  84. GITR interacts with the pro-apoptotic protein Siva and induces apoptosis
  85. Oxidative Stress and Apoptosis in Immune Diseases
  86. Role of GITR in activation response of T lymphocytes
  87. Gene Structure and Chromosomal Assignment of Mouse GITR, a Member of the Tumor Necrosis Factor/Nerve Growth Factor Receptor Family
  88. Identification of three novel mRNA splice variants of GITR
  89. Design and Synthesis of Modified Quinolones as Antitumoral Acridones
  90. Angiotensin converting enzyme deletion allele in different kinds of dementia disorders
  91. Antitumor activity of 2,2′-bipyridyl-6-carbothioamide: a ribonucleotide reductase inhibitor
  92. Apolipoprotein-E genotype in normal aging, age-associated memory impairment, Alzheimer's disease and vascular dementia patients
  93. A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis
  94. Short-Term Dexamethasone Treatment Modulates the Expression of the Murine TCRζ Gene Locus
  95. Dexamethasone modulates CD2 expression
  96. The 2,2′-Bipyridyl-6-carbothioamide copper (II) complex differs from the iron (II) complex in its biochemical effects in tumor cells, suggesting possible differences in the mechanism leading to cytotoxicity
  97. Ribonucleotide reductase inhibitors: new strategies for cancer chemotherapy
  98. Furanfurin and Thiophenfurin: Two Novel Tiazofurin Analogs. Synthesis, Structure, Antitumor Activity, and Interactions with Inosine Monophosphate Dehydrogenase
  99. T cell receptor ι an alternatively spliced product of the T cell receptor ζ gene
  100. Effect of dexamethasone on TCRζ gene expression
  101. Dexamethasone inhibits TCR/CD3 complex expression
  102. Chelating agents as potential antitumorals. 2-quinolylhydrazones and bis-2-quinolylhydrazones. I
  103. Dexamethasone and interleukins modulate apoptosis of murine thymocytes and peripheral T-lymphocytes
  104. 8-Aza Analogues of Deaza Purine Nucleosides. Synthesis and Biological Evaluation of 8-Aza-1-deazaadenosine and 2′-Deoxy-8-aza-1-deazaadenosine
  105. Synthesis and Evaluation of Anti-HIV-1 and Antitumor Activity of 2′,3′-didehydro-2′,3′-dideoxy-3-deazaadenosine, 2′,3′-dideoxy-3-Deazaadenosine and Some 2′,3′-dideoxy-3-deaza-adenosine 5′-dialkyl Phosphates1
  106. Synthesis and antitumor activity of 2-.beta.-D-ribofuranosyloxazole-4-carboxamide (oxazofurin)
  107. Implications and problems in analysing cytotoxic activity of hydroxyurea in combination with a potential inhibitor of ribonucleotide reductase*1
  108. Implications and problems in analysing cytotoxic activity of hydroxyurea in combination with a potential inhibitor of ribonucleotide reductase
  109. Early evaluation of a new 2,2′-bipyridyl derivative with potential inhibitory activity on the ribonucleotide reductase enzyme
  110. 3,7-Dideazapurine nucleosides. Synthesis and antitumor activity of 1-deazatubercidin and 2-chloro-2'-deoxy-3,7-dideazaadenosine