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  1. Detection of urinary miRNAs for diagnosis of clear cell renal cell carcinoma

    Article • Scientific Reports, December 2020, Springer Science + Business Media

    Prof Giuseppe Nocentini

  2. Immune modulation via T regulatory cell enhancement: disease‐modifying therapies for autoimmunity and their potential for chronic allergic and inflammatory diseases – An EAACI position paper of the Task Force on Immunopharmacology (TIPCO)

    Article • Allergy, June 2020, Wiley

    Prof Giuseppe Nocentini

  3. Expansion of regulatory T cells prevents type 1 diabetes onset by inhibiting islet destruction

    Article • Diabetes, March 2020, American Diabetes Association

    Prof Giuseppe Nocentini, Dr Luigi Cari

  4. Identification of 15 T Cell Restricted Genes Evaluates T Cell Infiltration of Human Healthy Tissues and Cancers and Shows Prognostic and Predictive Potential

    Article • International Journal of Molecular Sciences, October 2019, MDPI AG

    Prof Giuseppe Nocentini

  5. Evaluation of potential targets for ADCC induction against regulatory T cells in renal cell carcinoma

    Article • European Urology Supplements, October 2019, Elsevier

    Prof Giuseppe Nocentini

  6. The antibody frequently used to stain human GITR, does not bind GITR, leading to misleading results.

    Article • Clinical Cancer Research, September 2019, American Association for Cancer Research (AACR)

    Dr Luigi Cari, Prof Giuseppe Nocentini

  7. The first‐generation phosphodiesterase 5 inhibitors and their pharmacokinetic issue

    Article • Andrology, July 2019, Wiley

    Dr Luigi Cari, Professor Alessandro Zucchi, Prof Giuseppe Nocentini

  8. ENGINEERED ALGINATE MICROCAPSULES FOR MOLECULAR THERAPY TROUGH BIOLOGIC SECRETING CELLS

    Article • Tissue Engineering Part C Methods, April 2019, Mary Ann Liebert Inc

    Dr Luigi Cari, Prof Giuseppe Nocentini

  9. Context-Dependent Effect of Glucocorticoids on the Proliferation, Differentiation, and Apoptosis of Regulatory T Cells: A Review of the Empirical Evidence and Clinical Applications

    Article • International Journal of Molecular Sciences, March 2019, MDPI AG

    Dr Luigi Cari, Prof Giuseppe Nocentini

  10. Beta-carotene, telomerase activity and Alzheimer’s disease in old age subjects

    Article • European Journal of Nutrition, January 2019, Springer Science + Business Media

    Dr Luigi Cari, Prof Giuseppe Nocentini

  11. Telomeres Increasingly Develop Aberrant Structures in Aging Humans

    Article • The Journals of Gerontology Series A, November 2018, Oxford University Press (OUP)

    Dr Luigi Cari, Prof Giuseppe Nocentini

  12. Comparing biologicals and small molecule drug therapies for chronic respiratory diseases

    Article • Allergy, October 2018, Wiley

    Dr Luigi Cari, Prof Giuseppe Nocentini

  13. GITR is an interesting target for immunotherapy of cancers, infection and autoimmune diseases

    Article • Expert Opinion on Therapeutic Targets, August 2018, Taylor & Francis

    Prof Giuseppe Nocentini

  14. Triggering of GITR expands a subset of regulatory T cells and prevents diabetes development in mice

    Article • Diabetes, May 2018, American Diabetes Association

    Prof Giuseppe Nocentini

  15. Use of regulatory T cells to treat autoimmune diseases and prevent GVHD in murine models and humans

    Article • January 2018, Elsevier

    Dr Luigi Cari, Prof Giuseppe Nocentini

  16. Regulatory T cells (Tregs) expressing specific Treg markers that infiltrate 9 types of human cancers

    Article • OncoImmunology, November 2017, Taylor & Francis

    Dr Luigi Cari, Prof Giuseppe Nocentini

  17. The Proinflammatory Cytokine GITRL Contributes to TRAIL-mediated Neurotoxicity in the HCN-2 Human Neuronal Cell Line

    Article • Current Alzheimer Research, September 2017, Bentham Science Publishers

    Prof Giuseppe Nocentini

  18. Influence of chemotherapeutic drug-related gene polymorphisms on toxicity and survival of early breast cancer patients receiving adjuvant chemotherapy

    Article • BMC Cancer, July 2017, Springer Science + Business Media

    Prof Giuseppe Nocentini

  19. The role of GITR single-positive cells in immune homeostasis

    Article • Immunity Inflammation and Disease, February 2017, Wiley

    Dr Luigi Cari, Prof Giuseppe Nocentini

  20. GITR: A Modulator of Regulatory and Effector T-Cell Activity, Crucial in Tumour Rejection and Autoimmune Diseases

    Article • January 2017, Wiley

    Dr Luigi Cari, Prof Giuseppe Nocentini

  21. Modulation of tumor immunity: a patent evaluation of WO2015026684A1

    Article • Expert Opinion on Therapeutic Patents, February 2016, Informa Healthcare

    Dr Luigi Cari, Prof Giuseppe Nocentini

  22. Are we Able to Harness the Immunomodulatory Power of Cytokines for Novel Autoimmune Disease Treatments?

    Article • American Journal of Pharmacology and Toxicology, February 2015, Science Publications

    Prof Giuseppe Nocentini

  23. GITR+ regulatory T cells in the treatment of autoimmune diseases

    Article • Autoimmunity Reviews, February 2015, Elsevier

    Prof Giuseppe Nocentini

  24. A focused Real Time PCR strategy to determine GILZ expression in mouse tissues

    Article • Results in Immunology, January 2015, Elsevier

    Dr Luigi Cari, Prof Giuseppe Nocentini

  25. Glucocorticoid-Induced Tumour Necrosis Factor Receptor-Related Protein: A Key Marker of Functional Regulatory T Cells

    Article • Journal of Immunology Research, January 2015, Hindawi Publishing Corporation

    Dr Luigi Cari, Prof Giuseppe Nocentini

  26. The Clinical Pharmacology of Past, Present, and Future Glucocorticoids

    Article • January 2015, Springer Science + Business Media

    Prof Giuseppe Nocentini

  27. The Molecular and Cellular Mechanisms Responsible for the Anti-inflammatory and Immunosuppressive Effects of Glucocorticoids

    Article • January 2015, Springer Science + Business Media

    Prof Giuseppe Nocentini

  28. Expansion of regulatory GITR+CD25low/-CD4+ T cells in systemic lupus erythematosus patients

    Article • Arthritis Research & Therapy, September 2014, Springer Science + Business Media

    Prof Giuseppe Nocentini

  29. L-GILZ binds p53 and MDM2 and suppresses tumor growth through p53 activation in human cancer cells

    Article • Cell Death and Differentiation, August 2014, Springer Science + Business Media

    Prof Giuseppe Nocentini

  30. Transcriptional regulation of kinases downstream of the T cell receptor: another immunomodulatory mechanism of glucocorticoids

    Article • BMC Pharmacology and Toxicology, July 2014, Springer Science + Business Media

    Dr Katia Fettucciari, Dr Luigi Cari, Prof Giuseppe Nocentini

  31. Eicosapentaenoic Acid Activates RAS/ERK/C/EBPβ Pathway through H-Ras Intron 1 CpG Island Demethylation in U937 Leukemia Cells

    Article • PLoS ONE, January 2014, PLOS

    Prof Giuseppe Nocentini

  32. Glucocorticoid-Induced Tumor Necrosis Factor Receptor Family-Related Ligand Triggering Upregulates Vascular Cell Adhesion Molecule-1 and Intercellular Adhesion Molecule-1 and Promotes Leukocyte Adhesion

    Article • Journal of Pharmacology and Experimental Therapeutics, July 2013, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Prof Giuseppe Nocentini

  33. Characterization of a new regulatory CD4+ T cell subset in primary Sjogren's syndrome

    Article • Rheumatology, May 2013, Oxford University Press (OUP)

    Prof Giuseppe Nocentini

  34. L-GILZ forms a complex with p53 and mdm2 and suppresses tumor growth through p53 activation

    Article • Frontiers in Immunology, January 2013, Frontiers

    Prof Giuseppe Nocentini

  35. Expansion of CD4+CD25-GITR+ regulatory T-cell subset in the peripheral blood of patients with primary Sjögren's syndrome: correlation with disease activity

    Article • Reumatismo, December 2012, PAGEPress Publications

    Prof Giuseppe Nocentini

  36. Mechanisms of the anti-inflammatory effects of glucocorticoids: genomic and nongenomic interference with MAPK signaling pathways

    Article • The FASEB Journal, September 2012, Federation of American Societies For Experimental Biology (FASEB)

    Prof Giuseppe Nocentini

  37. The intracellular portion of GITR enhances NGF-promoted neurite growth through an inverse modulation of Erk and NF-κB signalling

    Article • Biology Open, August 2012, The Company of Biologists

    Prof Giuseppe Nocentini

  38. Pharmacological modulation of GITRL/GITR system: therapeutic perspectives

    Article • British Journal of Pharmacology, March 2012, Wiley

    Prof Giuseppe Nocentini

  39. CD8+T Cells: GITR Matters

    Article • The Scientific World JOURNAL, January 2012, Hindawi Publishing Corporation

    Prof Giuseppe Nocentini

  40. Balance between Regulatory T and Th17 Cells in Systemic Lupus Erythematosus: The Old and the New

    Article • Developmental Immunology, January 2012, Hindawi Publishing Corporation

    Prof Giuseppe Nocentini

  41. GITR Gene Deletion and GITR-Fc Soluble Protein Administration Inhibit Multiple Organ Failure Induced by Zymosan

    Article • Shock, September 2011, Wolters Kluwer Health

    Prof Giuseppe Nocentini

  42. CD4+CD25lowGITR+ cells: A novel human CD4+ T-cell population with regulatory activity

    Article • European Journal of Immunology, July 2011, Wiley

    Prof Giuseppe Nocentini

  43. Eicosapentaenoic Acid Demethylates a Single CpG That Mediates Expression of Tumor Suppressor CCAAT/Enhancer-binding Protein δ in U937 Leukemia Cells

    Article • Journal of Biological Chemistry, June 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Katia Fettucciari, Prof Giuseppe Nocentini

  44. Glucocorticoid-Induced TNFR family Related gene (GITR) enhances dendritic cell activity

    Article • Immunology Letters, March 2011, Elsevier

    Prof Giuseppe Nocentini

  45. The glucocorticoid-induced TNF receptor family-related protein (GITR) is critical to the development of acute pancreatitis in mice

    Article • January 2011, Wiley

    Prof Giuseppe Nocentini

  46. Effect of dietary saturated fatty acids on HNF-4α DNA binding activity and ApoCIII mRNA in sedentary rat liver

    Article • Molecular and Cellular Biochemistry, October 2010, Springer Science + Business Media

    Prof Giuseppe Nocentini

  47. Role of regulatory T cells in rheumatoid arthritis: facts and hypothesis

    Article • Autoimmunity Highlights, May 2010, Springer Science + Business Media

    Prof Giuseppe Nocentini

  48. Neutralization of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Reduces Spinal Cord Injury Damage in Mice

    Article • Neuropsychopharmacology, January 2010, Nature

    Prof Giuseppe Nocentini

  49. Identification of regulatory T cells in systemic lupus erythematosus

    Article • Autoimmunity Reviews, March 2009, Elsevier

    Prof Giuseppe Nocentini

  50. GITR: A Modulator of Immune Response and Inflammation

    Article • January 2009, Springer Science + Business Media

    Prof Giuseppe Nocentini

  51. The GITRL–GITR system alters TLR-4 expression on DC during fungal infection

    Article • Cellular Immunology, January 2009, Elsevier

    Prof Giuseppe Nocentini

  52. Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity

    Article • European Journal of Cancer, June 2008, Elsevier

    Prof Giuseppe Nocentini

  53. Glucocorticoid-Induced Tumor Necrosis Factor Receptor-Related (GITR)-Fc Fusion Protein Inhibits GITR Triggering and Protects from the Inflammatory Response after Spinal Cord Injury

    Article • Molecular Pharmacology, March 2008, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Prof Giuseppe Nocentini

  54. Peroxisome Proliferator-Activated Receptor-α Contributes to the Anti-Inflammatory Activity of Glucocorticoids

    Article • Molecular Pharmacology, November 2007, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Prof Giuseppe Nocentini

  55. Glucocorticoid-Induced TNFR-Related Protein Lowers the Threshold of CD28 Costimulation in CD8+ T Cells

    Article • The Journal of Immunology, October 2007, The American Association of Immunologists

    Prof Giuseppe Nocentini

  56. Modulation of Acute and Chronic Inflammation of the Lung by GITR and its Ligand

    Article • Annals of the New York Academy of Sciences, June 2007, Wiley

    Prof Giuseppe Nocentini

  57. GITR/GITRL: More than an effector T cell co-stimulatory system

    Article • European Journal of Immunology, May 2007, Wiley

    Prof Giuseppe Nocentini

  58. Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy

    Article • Nature Medicine, April 2007, Nature

    Professor FRANCESCA FALLARINO, Prof Giuseppe Nocentini

  59. GITR-GITRL System, A Novel Player in Shock and Inflammation

    Article • The Scientific World JOURNAL, January 2007, Hindawi Publishing Corporation

    Dr Katia Fettucciari, Prof Giuseppe Nocentini

  60. Genetic and pharmacological inhibition of GITR-GITRL interaction reduces chronic lung injury induced by bleomycin instillation

    Article • The FASEB Journal, November 2006, Federation of American Societies For Experimental Biology (FASEB)

    Prof Giuseppe Nocentini

  61. Interaction of CTSD and A2M polymorphisms in the risk for Alzheimer's disease

    Article • Journal of the Neurological Sciences, September 2006, Elsevier

    Prof Giuseppe Nocentini

  62. Modulation of Pro- and Antiapoptotic Molecules in Double-Positive (CD4+CD8+) Thymocytes following Dexamethasone Treatment

    Article • Journal of Pharmacology and Experimental Therapeutics, August 2006, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Katia Fettucciari, Prof Giuseppe Nocentini

  63. Proinflammatory Role of Glucocorticoid-Induced TNF Receptor-Related Gene in Acute Lung Inflammation

    Article • The Journal of Immunology, June 2006, The American Association of Immunologists

    Prof Giuseppe Nocentini

  64. Dietary PUFA modulate the expression of proliferation and differentiation markers in Morris 3924A hepatoma cells

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, December 2005, Elsevier

    Prof Giuseppe Nocentini

  65. The Glucocorticoid-Induced Tumor Necrosis Factor Receptor-Related Gene Modulates the Response to Candida albicans Infection

    Article • Infection and Immunity, November 2005, ASM Journals

    Prof Giuseppe Nocentini

  66. GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily

    Article • European Journal of Immunology, April 2005, Wiley

    Prof Giuseppe Nocentini

  67. Glucocorticoid-induced TNF receptor family gene (GITR) knockout mice exhibit a resistance to splanchnic artery occlusion (SAO) shock

    Article • August 2004, Wiley

    Prof Giuseppe Nocentini

  68. Frontline: GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations

    Article • European Journal of Immunology, March 2004, Wiley

    Prof Giuseppe Nocentini

  69. Dietary α-linolenic acid reduces COX-2 expression and induces apoptosis of hepatoma cells

    Article • Journal of Lipid Research, October 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Giuseppe Nocentini

  70. Cathepsin D Polymorphism in Italian Elderly Subjects with Sporadic Late-Onset Alzheimer’s Disease

    Article • Dementia and Geriatric Cognitive Disorders, July 2003, Karger Publishers

    Prof Giuseppe Nocentini

  71. Enhanced expression of hepatic lipogenic enzymes in an animal model of sedentariness

    Article • Journal of Lipid Research, January 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Giuseppe Nocentini

  72. GITR interacts with the pro-apoptotic protein Siva and induces apoptosis

    Article • Cell Death and Differentiation, December 2002, Springer Science + Business Media

    Prof Giuseppe Nocentini

  73. Oxidative Stress and Apoptosis in Immune Diseases

    Article • International Journal of Immunopathology and Pharmacology, September 2002, SAGE Publications

    Prof Giuseppe Nocentini

  74. Role of GITR in activation response of T lymphocytes

    Article • Blood, April 2002, American Society of Hematology

    Prof Giuseppe Nocentini

  75. Gene Structure and Chromosomal Assignment of Mouse GITR, a Member of the Tumor Necrosis Factor/Nerve Growth Factor Receptor Family

    Article • DNA and Cell Biology, April 2000, Mary Ann Liebert Inc

    Prof Giuseppe Nocentini

  76. Identification of three novel mRNA splice variants of GITR

    Article • Cell Death and Differentiation, April 2000, Springer Science + Business Media

    Prof Giuseppe Nocentini

  77. Design and Synthesis of Modified Quinolones as Antitumoral Acridones 1

    Article • Journal of Medicinal Chemistry, June 1999, American Chemical Society (ACS)

    Professor Claudia Sissi, Prof Giuseppe Nocentini

  78. Angiotensin converting enzyme deletion allele in different kinds of dementia disorders

    Article • Neuroscience Letters, May 1999, Elsevier

    Prof Giuseppe Nocentini

  79. Article • Molecular and Cellular Biochemistry, January 1999, Springer Science + Business Media

    Prof Giuseppe Nocentini

  80. Antitumor activity of 2,2′-bipyridyl-6-carbothioamide: a ribonucleotide reductase inhibitor

    Article • General Pharmacology The Vascular System, November 1997, Elsevier

    Prof Giuseppe Nocentini

  81. Apolipoprotein-E genotype in normal aging, age-associated memory impairment, Alzheimer's disease and vascular dementia patients

    Article • Neuroscience Letters, August 1997, Elsevier

    Prof Giuseppe Nocentini

  82. A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis

    Article • Proceedings of the National Academy of Sciences, June 1997, Proceedings of the National Academy of Sciences

    Prof Giuseppe Nocentini

  83. Short-Term Dexamethasone Treatment Modulates the Expression of the Murine TCRζ Gene Locus

    Article • Cellular Immunology, June 1997, Elsevier

    Prof Giuseppe Nocentini

  84. Article • Molecular and Cellular Biochemistry, January 1997, Springer Science + Business Media

    Prof Giuseppe Nocentini

  85. Dexamethasone modulates CD2 expression

    Article • International Journal of Immunopharmacology, December 1996, Elsevier

    Prof Giuseppe Nocentini

  86. The 2,2′-Bipyridyl-6-carbothioamide copper (II) complex differs from the iron (II) complex in its biochemical effects in tumor cells, suggesting possible differences in the mechanism leading to cytotoxicity

    Article • Biochemical Pharmacology, July 1996, Elsevier

    Prof Giuseppe Nocentini

  87. Ribonucleotide reductase inhibitors: new strategies for cancer chemotherapy

    Article • Critical Reviews in Oncology/Hematology, March 1996, Elsevier

    Prof Giuseppe Nocentini

  88. Furanfurin and Thiophenfurin: Two Novel Tiazofurin Analogs. Synthesis, Structure, Antitumor Activity, and Interactions with Inosine Monophosphate Dehydrogenase

    Article • Journal of Medicinal Chemistry, September 1995, American Chemical Society (ACS)

    Prof Giuseppe Nocentini

  89. T cell receptor ι an alternatively spliced product of the T cell receptor ζ gene

    Article • European Journal of Immunology, May 1995, Wiley

    Prof Giuseppe Nocentini

  90. Effect of dexamethasone on TCRζ gene expression

    Article • January 1995, Elsevier

    Prof Giuseppe Nocentini

  91. Dexamethasone inhibits TCR/CD3 complex expression

    Article • January 1995, Elsevier

    Prof Giuseppe Nocentini

  92. Chelating agents as potential antitumorals. 2-quinolylhydrazones and bis-2-quinolylhydrazones. I

    Article • European Journal of Medicinal Chemistry, January 1995, Elsevier

    Prof Giuseppe Nocentini

  93. Dexamethasone and interleukins modulate apoptosis of murine thymocytes and peripheral T-lymphocytes

    Article • July 1994, Elsevier

    Prof Giuseppe Nocentini

  94. 8-Aza Analogues of Deaza Purine Nucleosides. Synthesis and Biological Evaluation of 8-Aza-1-deazaadenosine and 2′-Deoxy-8-aza-1-deazaadenosine

    Article • Nucleosides and Nucleotides, June 1992, Taylor & Francis

    Prof Giuseppe Nocentini

  95. Synthesis and antitumor activity of 2-.beta.-D-ribofuranosyloxazole-4-carboxamide (oxazofurin)

    Article • Journal of Medicinal Chemistry, October 1990, American Chemical Society (ACS)

    Prof Giuseppe Nocentini

  96. Implications and problems in analysing cytotoxic activity of hydroxyurea in combination with a potential inhibitor of ribonucleotide reductase*1

    Article • Pharmacological Research, October 1990, Elsevier

    Prof Giuseppe Nocentini

  97. Implications and problems in analysing cytotoxic activity of hydroxyurea in combination with a potential inhibitor of ribonucleotide reductase

    Article • Cancer Chemotherapy and Pharmacology, September 1990, Springer Science + Business Media

    Prof Giuseppe Nocentini

  98. 3,7-Dideazapurine nucleosides. Synthesis and antitumor activity of 1-deazatubercidin and 2-chloro-2'-deoxy-3,7-dideazaadenosine

    Article • Journal of Medicinal Chemistry, July 1989, American Chemical Society (ACS)

    Prof Giuseppe Nocentini