All Stories

  1. Clostridioides difficile meets the adenosine system: the art of manipulating host homeostasis

    Article • Journal of Biomedical Science, July 2025, Springer Science + Business Media

    Dr Katia Fettucciari

  2. PhosphoLipidome Alteration Induced by Clostridioides difficile Toxin B in Enteric Glial Cells

    Article • Cells, June 2024, MDPI AG

    Dr Katia Fettucciari, Professor Gabrio Bassotti

  3. Pro-Inflammatory Cytokines Enhanced In Vitro Cytotoxic Activity of Clostridioides difficile Toxin B in Enteric Glial Cells: The Achilles Heel of Clostridioides difficile Infection?

    Article • International Journal of Molecular Sciences, January 2024, MDPI AG

    Dr Katia Fettucciari, Professor Gabrio Bassotti

  4. Role of the Alteration in Calcium Homeostasis in Cell Death Induced by Clostridioides difficile Toxin A and Toxin B

    Article • Biology, August 2023, MDPI AG

    Dr Katia Fettucciari, Professor Gabrio Bassotti

  5. Clostridioides difficile and colorectal cancer: a dangerous liaison

    Article • European Journal of Gastroenterology & Hepatology, July 2023, Wolters Kluwer Health

    Dr Katia Fettucciari

  6. Clostridioides difficile Toxin B Induced Senescence: A New Pathologic Player for Colorectal Cancer?

    Article • International Journal of Molecular Sciences, May 2023, MDPI AG

    Dr Katia Fettucciari, Professor Gabrio Bassotti

  7. Cytotoxic synergism of Clostridioides difficile toxin B with proinflammatory cytokines in subjects with inflammatory bowel diseases

    Article • World Journal of Gastroenterology, January 2023, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Dr Katia Fettucciari

  8. The Polyunsaturated Fatty Acid EPA, but Not DHA, Enhances Neurotrophic Factor Expression through Epigenetic Mechanisms and Protects against Parkinsonian Neuronal Cell Death

    Article • International Journal of Molecular Sciences, December 2022, MDPI AG

    Dr Katia Fettucciari

  9. Clostridioides difficile toxin B alone and with pro-inflammatory cytokines induces apoptosis in enteric glial cells by activating three different signalling pathways mediated by caspases, calpains and cathepsin B

    Article • Cellular and Molecular Life Sciences, July 2022, Springer Science + Business Media

    Dr Katia Fettucciari, Professor Gabrio Bassotti

  10. Clostridioides difficile Infection in Patients with Inflammatory Bowel Disease May be Favoured by the Effects of Proinflammatory Cytokines on the Enteroglial Network

    Article • Journal of Inflammation Research, December 2021, Taylor & Francis

    Professor Gabrio Bassotti, Dr Katia Fettucciari

  11. Proinflammatory Cytokines: Possible Accomplices for the Systemic Effects of Clostridioides difficile Toxin B

    Article • Journal of Inflammation Research, January 2021, Taylor & Francis

    Professor Gabrio Bassotti, Dr Katia Fettucciari

  12. Invisible steps for a global endemy: molecular strategies adopted by Clostridioides difficile

    Article • Therapeutic Advances in Gastroenterology, January 2021, SAGE Publications

    Dr Katia Fettucciari

  13. Crosstalk between Long-Term Sublethal Oxidative Stress and Detrimental Inflammation as Potential Drivers for Age-Related Retinal Degeneration

    Article • Antioxidants, December 2020, MDPI AG

    Dr Katia Fettucciari

  14. The efficacy of the anticancer 3-bromopyruvate is potentiated by antimycin and menadione by unbalancing mitochondrial ROS production and disposal in U118 glioblastoma cells

    Article • Heliyon, December 2020, Elsevier

    Dr Katia Fettucciari

  15. The cytotoxic synergy betweenClostridioides difficiletoxin B and proinflammatory cytokines: an unholy alliance favoring the onset ofClostridioides difficileinfection and relapses

    Article • MicrobiologyOpen, July 2020, Wiley

    Professor Gabrio Bassotti, Dr Katia Fettucciari

  16. Acetamidine-Based iNOS Inhibitors as Molecular Tools to Counteract Inflammation in BV2 Microglial Cells

    Article • Molecules, June 2020, MDPI AG

    Dr Katia Fettucciari

  17. Guanylin, Uroguanylin and Guanylate Cyclase-C Are Expressed in the Gastrointestinal Tract of Horses

    Article • Frontiers in Physiology, September 2019, Frontiers

    Dr Katia Fettucciari

  18. Gentamicin Targets Acid Sphingomyelinase in Cancer: The Case of the Human Gastric Cancer NCI-N87 Cells

    Article • International Journal of Molecular Sciences, September 2019, MDPI AG

    Dr Katia Fettucciari

  19. Clostridium difficile toxin B induces senescence in enteric glial cells: A potential new mechanism of Clostridium difficile pathogenesis

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, December 2018, Elsevier

    Dr Katia Fettucciari

  20. Palmitate lipotoxicity in enteric glial cells: Lipid remodeling and mitochondrial ROS are responsible for cyt c release outside mitochondria

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, August 2018, Elsevier

    Dr Katia Fettucciari

  21. Nicotine induces apoptosis in human osteoblasts via a novel mechanism driven by H 2 O 2 and entailing Glyoxalase 1-dependent MG-H1 accumulation leading to TG2-mediated NF-kB desensitization: Implication for smokers-related osteoporosis

    Article • Free Radical Biology and Medicine, March 2018, Elsevier

    Dr Katia Fettucciari

  22. VDR independent induction of acid-sphingomyelinase by 1,23(OH)2 D3 in gastric cancer cells: Impact on apoptosis and cell morphology

    Article • Biochimie, March 2018, Elsevier

    Dr Katia Fettucciari

  23. Effects of probiotic bacteria on mucosal polyamines levels in dogs with IBD and colonic polyps: a preliminary study

    Article • Beneficial Microbes, February 2018, Wageningen Academic Publishers

    Dr Katia Fettucciari, Professor Gabrio Bassotti, Giacomo Rossi

  24. Clostridium difficile-related postinfectious IBS: a case of enteroglial microbiological stalking and/or the solution of a conundrum?

    Article • Cellular and Molecular Life Sciences, December 2017, Springer Science + Business Media

    Professor Gabrio Bassotti, Dr Katia Fettucciari

  25. Enteric glial cells counteract Clostridium difficile Toxin B through a NADPH oxidase/ROS/JNK/caspase-3 axis, without involving mitochondrial pathways

    Article • Scientific Reports, March 2017, Springer Science + Business Media

    Dr Katia Fettucciari

  26. Effects of Single-Dose Prucalopride on Intestinal Hypomotility in Horses: Preliminary Observations

    Article • Scientific Reports, January 2017, Springer Science + Business Media

    Dr Katia Fettucciari

  27. Enteric glial cells (EGC) are susceptible to C. difficile toxin B (TcdB)

    Article • Cellular and Molecular Life Sciences, November 2016, Springer Science + Business Media

    Dr Katia Fettucciari

  28. Erratum

    Article • International Journal of Cancer, August 2015, Wiley

    Dr Katia Fettucciari

  29. Macrophage induced gelsolin in response to Group B Streptococcus (GBS)

    Article • Cellular Microbiology, September 2014, Wiley

    Dr Katia Fettucciari

  30. Transcriptional regulation of kinases downstream of the T cell receptor: another immunomodulatory mechanism of glucocorticoids

    Article • BMC Pharmacology and Toxicology, July 2014, Springer Science + Business Media

    Dr Katia Fettucciari, Dr Luigi Cari, Prof Giuseppe Nocentini

  31. Impairment of brain mitochondrial functions by β-hemolytic Group B Streptococcus. Effect of cardiolipin and phosphatidylcholine

    Article • Journal of Bioenergetics and Biomembranes, August 2013, Springer Science + Business Media

    Dr Katia Fettucciari

  32. A novel mechanism of methylglyoxal cytotoxicity in prostate cancer cells

    Article • The International Journal of Biochemistry & Cell Biology, April 2013, Elsevier

    Dr Katia Fettucciari

  33. Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction

    Article • European Journal of Immunology, December 2012, Wiley

    Dr Katia Fettucciari

  34. γ-Secretase inhibitor I induces apoptosis in chronic lymphocytic leukemia cells by proteasome inhibition, endoplasmic reticulum stress increase and notch down-regulation

    Article • International Journal of Cancer, October 2012, Wiley

    Dr Katia Fettucciari

  35. Role of glyoxalase I in the proliferation and apoptosis control of human LNCaP and PC3 prostate cancer cells

    Article • The Prostate, June 2012, Wiley

    Dr Katia Fettucciari

  36. Eicosapentaenoic Acid Demethylates a Single CpG That Mediates Expression of Tumor Suppressor CCAAT/Enhancer-binding Protein δ in U937 Leukemia Cells

    Article • Journal of Biological Chemistry, June 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Katia Fettucciari, Prof Giuseppe Nocentini

  37. GBS disrupts by calpain macrophage cytoskeleton

    Article • Cellular Microbiology, March 2011, Wiley

    Dr Katia Fettucciari

  38. Novel targets for endoplasmic reticulum stress-induced apoptosis in B-CLL

    Article • Blood, October 2010, American Society of Hematology

    Dr Katia Fettucciari

  39. Protein expression changes induced in murine peritoneal macrophages by Group B Streptococcus

    Article • PROTEOMICS, March 2010, Wiley

    Dr Katia Fettucciari

  40. Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells

    Article • Blood, January 2009, American Society of Hematology

    Dr Katia Fettucciari

  41. GITR-GITRL System, A Novel Player in Shock and Inflammation

    Article • The Scientific World JOURNAL, January 2007, Hindawi Publishing Corporation

    Dr Katia Fettucciari, Prof Giuseppe Nocentini

  42. Interleukin-7–Engineered Mesenchymal Cells: In Vitro Effects on Naive T-Cell Population

    Article • Biology of Blood and Marrow Transplantation, December 2006, Elsevier

    Dr Katia Fettucciari

  43. Modulation of Pro- and Antiapoptotic Molecules in Double-Positive (CD4+CD8+) Thymocytes following Dexamethasone Treatment

    Article • Journal of Pharmacology and Experimental Therapeutics, August 2006, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Katia Fettucciari, Prof Giuseppe Nocentini

  44. Group B Streptococcus (GBS) induces macrophage apoptosis by calpain activation

    Article • The Journal of Immunology, June 2006, The American Association of Immunologists

    Dr Katia Fettucciari

  45. Graft engineering for allogeneic haploidentical stem cell transplantation

    Article • Blood Cells Molecules and Diseases, November 2004, Elsevier

    Dr Katia Fettucciari

  46. Effect of trichostatin a and 5′-azacytidine on transgene reactivation in U937 transduced cells

    Article • Pharmacological Research, April 2003, Elsevier

    Dr Katia Fettucciari

  47. Involvement of mitogen-activated protein kinases in Group B Streptococcus-induced macrophage apoptosis

    Article • Pharmacological Research, April 2003, Elsevier

    Dr Katia Fettucciari

  48. Group B streptococcus (GBS) modifies macrophage phosphatidylserine metabolism during induction of apoptosis

    Article • FEBS Letters, May 2002, Wiley

    Dr Katia Fettucciari

  49. In Vivo Demethylation of a MoMuLV Retroviral Vector Expressing the Herpes Simplex Thymidine Kinase Suicide Gene by 5′ Azacytidine

    Article • Stem Cells, November 2000, Wiley

    Dr Katia Fettucciari

  50. Group B Streptococcus Induces Apoptosis in Macrophages

    Article • The Journal of Immunology, October 2000, The American Association of Immunologists

    Dr Katia Fettucciari

  51. Differential Role of p38 and c-Jun N-Terminal Kinase 1 Mitogen-Activated Protein Kinases in NK Cell Cytotoxicity

    Article • The Journal of Immunology, August 2000, The American Association of Immunologists

    Dr Katia Fettucciari

  52. In vitro Effects of Meropenem and Imipenem/Cilastatin on Some Functions of Human Natural Effector Cells

    Article • Chemotherapy, January 2000, Karger Publishers

    Dr Katia Fettucciari

  53. Cytokine Response to Group B Streptococcus Infection in Mice

    Article • Scandinavian Journal of Immunology, April 1998, Wiley

    Dr Katia Fettucciari

  54. Group B streptococci persist inside macrophages

    Article • Immunology, January 1998, Wiley

    Dr Katia Fettucciari

  55. Activation of cytokine genes during primary and anamnestic immune response to inactivated C. albicans

    Article • Immunology, September 1996, Wiley

    Dr Katia Fettucciari

  56. Activity Inhibition of Cytolytic Lymphocytes by Omeprazole

    Article • Scandinavian Journal of Immunology, September 1996, Wiley

    Dr Katia Fettucciari

  57. Cytokine Response to Inactivated Candida albicans in Mice

    Article • Cellular Immunology, May 1995, Elsevier

    Dr Katia Fettucciari

  58. Induction and Persistence in Vivo of NK/LAK Activity by a Mannoprotein Component of Candida albicans Cell Wall

    Article • Cellular Immunology, May 1994, Elsevier

    Dr Katia Fettucciari