All Stories

  1. Antibodies against MLC1 found in patients with NMOSD-like disease mediate astrocytopathy in rodent models

    Article • Science Translational Medicine, August 2026, American Association for the Advancement of Science

    Professor Fredrik Piehl

  2. Targeting progressive multiple sclerosis: Toward mechanism‐informed precision medicine

    Article • Journal of Internal Medicine, July 2026, Wiley

    Professor Fredrik Piehl

  3. Drivers of Rising Prevalence in Major Motor Neurodegenerative Diseases

    Article • Neurology, July 2026, Wolters Kluwer Health

    Professor Fredrik Piehl

  4. Comparable Infection Risk of Ocrelizumab and Rituximab in Multiple Sclerosis in a Nationwide Swedish Cohort Study

    Article • Annals of Neurology, June 2026, Wiley

    Professor Fredrik Piehl

  5. Correction: Stability in Cognition and Employment in People with Relapsing Multiple Sclerosis Treated with Cladribine Tablets: Two‑year Phase IV CLARIFY‑MS Study

    Article • Neurology and Therapy, June 2026, Springer Science + Business Media

    Professor Fredrik Piehl, Dr. Alessandra Solari

  6. Comorbidities for Predicting Progression Independent of Relapse Activity in Multiple Sclerosis Treated With B‐Cell Depletion

    Article • European Journal of Neurology, June 2026, Wiley

    Professor Fredrik Piehl

  7. Treatment persistence in paediatric-onset multiple sclerosis: A Swedish nationwide registry study

    Article • Multiple Sclerosis Journal, May 2026, SAGE Publications

    Professor Fredrik Piehl

  8. Temporal trends in the incidence and prevalence of multiple sclerosis in Sweden 2001-2021

    Article • Neuroepidemiology, May 2026, Karger Publishers

    Professor Fredrik Piehl

  9. Divergence of C4A and C4B in first-episode psychosis: Insights from CSF and plasma immune profiling

    Article • Translational Psychiatry, April 2026, Springer Science + Business Media

    Professor Fredrik Piehl

  10. Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

    Article • Annals of Clinical and Translational Neurology, April 2026, Wiley

    Professor Fredrik Piehl

  11. Comorbidities and Treatment Patterns in People With Myasthenia Gravis in Denmark, Finland and Sweden: A Population‐Based Observational Study

    Article • Muscle & Nerve, March 2026, Wiley

    Professor Fredrik Piehl

  12. Stability in Cognition and Employment in People with Relapsing Multiple Sclerosis Treated with Cladribine Tablets: Two-year Phase IV CLARIFY-MS Study

    Article • Neurology and Therapy, March 2026, Springer Science + Business Media

    Professor Fredrik Piehl, Dr. Alessandra Solari

  13. Changes in Multiple Sclerosis Clinical Care and Outcomes During the COVID‐19 Era: A Population‐Wide Study

    Article • Acta Neurologica Scandinavica, January 2026, Wiley

    Professor Fredrik Piehl

  14. Correlates of patient reported quality of life in a large multiple sclerosis cohort encompassing the COVID-19 pandemic period

    Article • Multiple Sclerosis and Related Disorders, December 2025, Elsevier

    Professor Fredrik Piehl

  15. A human pan-disease blood atlas of the circulating proteome

    Article • Science, October 2025, American Association for the Advancement of Science

    Professor Fredrik Piehl

  16. Granulocyte and astrocyte markers distinguish MOG-antibody disease and neuromyelitis optica from multiple sclerosis

    Article • Brain, September 2025, Oxford University Press (OUP)

    Professor Fredrik Piehl

  17. Beneficial impact of physical activity on multiple sclerosis disability progression

    Article • Journal of Neurology Neurosurgery & Psychiatry, September 2025, BMJ

    Professor Fredrik Piehl

  18. Cardiovascular protein profiling in patients with first-episode psychosis

    Article • Schizophrenia, June 2025, Springer Science + Business Media

    Professor Fredrik Piehl

  19. Validation of the Swedish Multiple Sclerosis registry for pediatric-onset multiple sclerosis

    Article • Multiple Sclerosis Journal - Experimental Translational and Clinical, January 2025, SAGE Publications

    Professor Fredrik Piehl

  20. Fluid biomarkers of chronic traumatic brain injury

    Article • Nature Reviews Neurology, October 2024, Springer Science + Business Media

    Professor Fredrik Piehl

  21. Misdiagnosis and underdiagnosis of multiple sclerosis: A systematic review and meta-analysis

    Article • Multiple Sclerosis Journal, September 2024, SAGE Publications

    Professor Fredrik Piehl

  22. Impact of previous treatment history and B-cell depletion treatment duration on infection risk in relapsing-remitting multiple sclerosis: a nationwide cohort study

    Article • Journal of Neurology Neurosurgery & Psychiatry, May 2024, BMJ

    Professor Fredrik Piehl

  23. Trajectories of self-reported fatigue following initiation of multiple sclerosis disease-modifying therapy

    Article • Journal of Neurology Neurosurgery & Psychiatry, May 2024, BMJ

    Professor Fredrik Piehl

  24. Neurofilaments as biomarkers in neurological disorders — towards clinical application

    Article • Nature Reviews Neurology, April 2024, Springer Science + Business Media

    Professor Fredrik Piehl, Professor Tjalf Ziemssen

  25. Epidemiology of myasthenia gravis in Denmark, Finland and Sweden: a population-based observational study

    Article • Journal of Neurology Neurosurgery & Psychiatry, March 2024, BMJ

    Professor Fredrik Piehl

  26. Real‐World Healthcare Cost Savings and Reduced Relapse Rate with Off‐Label Rituximab versus Disease‐Modifying Treatments Approved for Relapsing–Remitting Multiple Sclerosis: A Nationwide Cost‐Effectiveness Study

    Article • Annals of Neurology, March 2024, Wiley

    Professor Fredrik Piehl

  27. Generalized myasthenia gravis with acetylcholine receptor antibodies: A guidance for treatment

    Article • European Journal of Neurology, February 2024, Wiley

    Professor Fredrik Piehl

  28. COVID-19–Related Enhancement for the COMBAT-MS Study

    Article • November 2023, Patient-Centered Outcomes Reserach Institute

    Professor Fredrik Piehl

  29. Improvements in quality of life over 2 years with cladribine tablets in people with relapsing multiple sclerosis: The CLARIFY-MS study

    Article • Multiple Sclerosis Journal, November 2023, SAGE Publications

    Professor Fredrik Piehl, Dr. Alessandra Solari

  30. Comparing the Safety and Effectiveness of Different Medicines to Treat Multiple Sclerosis – The COMBAT-MS Study

    Article • November 2023, Patient-Centered Outcomes Reserach Institute

    Professor Fredrik Piehl

  31. Multiple Sclerosis, Disease-Modifying Therapies, and Infections

    Article • Neurology Neuroimmunology & Neuroinflammation, November 2023, Wolters Kluwer Health

    Professor Fredrik Piehl

  32. Systemic Capillary Leak Syndrome With Cerebral Involvement in a C9orf72 Expansion Carrier

    Article • Neurology Genetics, August 2023, Wolters Kluwer Health

    Professor Fredrik Piehl

  33. Granulocyte activation markers in cerebrospinal fluid differentiate acute neuromyelitis spectrum disorder from multiple sclerosis

    Article • Journal of Neurology Neurosurgery & Psychiatry, April 2023, BMJ

    Professor Fredrik Piehl

  34. Multiple sclerosis, disease-modifying drugs and risk for adverse perinatal and pregnancy outcomes: Results from a population-based cohort study

    Article • Multiple Sclerosis Journal, April 2023, SAGE Publications

    Professor Fredrik Piehl

  35. Comparing the Safety of Medicines to Treat MS during the COVID-19 Pandemic

    Article • April 2023, Patient-Centered Outcomes Reserach Institute

    Professor Fredrik Piehl

  36. Sustained Low Relapse Rate With Highly Variable B-Cell Repopulation Dynamics With Extended Rituximab Dosing Intervals in Multiple Sclerosis

    Article • Neurology Neuroimmunology & Neuroinflammation, January 2023, Wolters Kluwer Health

    Professor Fredrik Piehl

  37. T cell responses at diagnosis of amyotrophic lateral sclerosis predict disease progression

    Article • Nature Communications, November 2022, Springer Science + Business Media

    Professor Fredrik Piehl

  38. Low-dose rituximab should be used for treating MS in resource-limited settings: Yes

    Article • Multiple Sclerosis Journal, April 2022, SAGE Publications

    Professor Thomas Mathew, Professor Fredrik Piehl

  39. The Karolinska NeuroCOVID study protocol: Neurocognitive impairment, biomarkers and advanced imaging in critical care survivors

    Article • Acta Anaesthesiologica Scandinavica, April 2022, Wiley

    Professor Fredrik Piehl

  40. Demyelinating events following anti‐tumor necrosis factor alpha therapy: Rare but challenging to treat

    Article • European Journal of Neurology, March 2022, Wiley

    Professor Fredrik Piehl

  41. Correlation between leukocyte phenotypes and prognosis of amyotrophic lateral sclerosis

    Article • eLife, March 2022, eLife

    Professor Fredrik Piehl

  42. Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study

    Article • The Lancet Neurology, March 2022, Elsevier

    Professor Fredrik Piehl

  43. The risk of infections for multiple sclerosis and neuromyelitis optica spectrum disorder disease-modifying treatments: Eighth European Committee for Treatment and Research in Multiple Sclerosis Focused Workshop Review. April 2021

    Article • Multiple Sclerosis Journal, February 2022, SAGE Publications

    Professor Fredrik Piehl

  44. Automatic deep learning multicontrast corpus callosum segmentation in multiple sclerosis

    Article • Journal of Neuroimaging, January 2022, Wiley

    Professor Fredrik Piehl

  45. Treatment satisfaction, safety, and tolerability of cladribine tablets in patients with highly active relapsing multiple sclerosis: CLARIFY-MS study 6-month interim analysis

    Article • Multiple Sclerosis and Related Disorders, January 2022, Elsevier

    Professor Dawn Langdon, Professor Fredrik Piehl, Dr. Alessandra Solari

  46. Dilated Virchow-Robin Spaces are a Marker for Arterial Disease in Multiple Sclerosis

    Article • January 2022, Elsevier

    Professor Fredrik Piehl

  47. Autoimmunity and long-term safety and efficacy of alemtuzumab for multiple sclerosis: Benefit/risk following review of trial and post-marketing data

    Article • Multiple Sclerosis Journal, December 2021, SAGE Publications

    Professor Fredrik Piehl, Professor Tjalf Ziemssen

  48. Rituximab Infusion Timing, Cumulative Dose, and Hospitalization for COVID-19 in Persons With Multiple Sclerosis in Sweden

    Article • JAMA Network Open, December 2021, American Medical Association (AMA)

    Professor Fredrik Piehl

  49. Screening for pathogenic neuronal autoantibodies in serum and CSF of patients with first-episode psychosis

    Article • Translational Psychiatry, November 2021, Springer Science + Business Media

    Professor Fredrik Piehl

  50. Association of Infectious Mononucleosis in Childhood and Adolescence With Risk for a Subsequent Multiple Sclerosis Diagnosis Among Siblings

    Article • JAMA Network Open, October 2021, American Medical Association (AMA)

    scott montgomery, Professor Fredrik Piehl

  51. Patient-Reported Symptom Severity in a Nationwide Myasthenia Gravis Cohort

    Article • Neurology, October 2021, Wolters Kluwer Health

    Professor Fredrik Piehl

  52. Treatment Escalation vs Immediate Initiation of Highly Effective Treatment for Patients With Relapsing-Remitting Multiple Sclerosis

    Article • JAMA Neurology, October 2021, American Medical Association (AMA)

    Professor Fredrik Piehl

  53. Development of humoral and cellular immunological memory against SARS-CoV-2 despite B cell depleting treatment in multiple sclerosis

    Article • iScience, September 2021, Elsevier

    Professor Fredrik Piehl

  54. Risk of depression in multiple sclerosis across disease-modifying therapies

    Article • Multiple Sclerosis Journal, July 2021, SAGE Publications

    Professor Fredrik Piehl

  55. ALS patients with concurrent neuroinflammatory disorders; a nationwide clinical records study

    Article • Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, July 2021, Taylor & Francis

    Professor Fredrik Piehl

  56. Complex Autoantibody Responses Occur following Moderate to Severe Traumatic Brain Injury

    Article • The Journal of Immunology, July 2021, Oxford University Press (OUP)

    Professor Fredrik Piehl

  57. Reduction of the risk of PML in natalizumab treated MS patients in Sweden: An effect of improved PML risk surveillance

    Article • Multiple Sclerosis and Related Disorders, May 2021, Elsevier

    Professor Fredrik Piehl

  58. Small noncoding RNA profiling across cellular and biofluid compartments and their implications for multiple sclerosis immunopathology

    Article • Proceedings of the National Academy of Sciences, April 2021, Proceedings of the National Academy of Sciences

    Professor Fredrik Piehl

  59. Neurofilament light chain as a marker for cortical atrophy in multiple sclerosis without radiological signs of disease activity

    Article • Journal of Internal Medicine, April 2021, Wiley

    Professor Fredrik Piehl

  60. Plasma bilirubin levels are reduced in first-episode psychosis patients and associates to working memory and duration of untreated psychosis

    Article • Scientific Reports, April 2021, Springer Science + Business Media

    Professor Fredrik Piehl

  61. Safety of Alemtuzumab and Autologous Hematopoietic Stem Cell Transplantation Compared to Noninduction Therapies for Multiple Sclerosis

    Article • Neurology, March 2021, Wolters Kluwer Health

    Professor Fredrik Piehl

  62. Fluid proteomics of CSF and serum reveal important neuroinflammatory proteins in blood–brain barrier disruption and outcome prediction following severe traumatic brain injury: a prospective, observational study

    Article • Critical Care, March 2021, Springer Science + Business Media

    Professor Fredrik Piehl

  63. Hospital-diagnosed infections before age 20 and risk of a subsequent multiple sclerosis diagnosis

    Article • Brain, March 2021, Oxford University Press (OUP)

    scott montgomery, Professor Fredrik Piehl

  64. Deep Learning Corpus Callosum Segmentation as a Neurodegenerative Marker in Multiple Sclerosis

    Article • Journal of Neuroimaging, February 2021, Wiley

    Professor Fredrik Piehl

  65. Differential effects on blood and cerebrospinal fluid immune protein markers and kynurenine pathway metabolites from aerobic physical exercise in healthy subjects

    Article • Scientific Reports, January 2021, Springer Science + Business Media

    Professor Fredrik Piehl

  66. Cerebrospinal fluid brevican and neurocan fragment patterns in human traumatic brain injury

    Article • Clinica Chimica Acta, January 2021, Elsevier

    Professor Fredrik Piehl

  67. Assessing the Preanalytical Variability of Plasma and Cerebrospinal Fluid Processing and Its Effects on Inflammation-Related Protein Biomarkers

    Article • Molecular & Cellular Proteomics, January 2021, Elsevier

    Professor Fredrik Piehl

  68. The Effect of Different National Treatment Strategies on Disability Outcome in Relapsing-Remitting Multiple Sclerosis: A Propensity Score Adjusted Comparison between Denmark and Sweden

    Article • January 2021, Elsevier

    Professor Fredrik Piehl

  69. Associations between autoimmune diseases and amyotrophic lateral sclerosis: a register-based study

    Article • Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, December 2020, Taylor & Francis

    Professor Fredrik Piehl

  70. Current and emerging disease modulatory therapies and treatment targets for multiple sclerosis

    Article • Journal of Internal Medicine, December 2020, Wiley

    Professor Fredrik Piehl

  71. Effect of Vitamin D on Experimental Autoimmune Neuroinflammation Is Dependent on Haplotypes Comprising Naturally Occurring Allelic Variants of CIITA (Mhc2ta)

    Article • Frontiers in Neurology, November 2020, Frontiers

    Professor Fredrik Piehl

  72. Disease activity in pregnancy and postpartum in women with MS who suspended rituximab and natalizumab

    Article • Neurology Neuroimmunology & Neuroinflammation, November 2020, Wolters Kluwer Health

    Professor Fredrik Piehl

  73. Dynamics of cerebrospinal fluid levels of matrix metalloproteinases in human traumatic brain injury

    Article • Scientific Reports, October 2020, Springer Science + Business Media

    Professor Fredrik Piehl

  74. Absence of Neuronal Autoantibodies in Neuropsychiatric Systemic Lupus Erythematosus

    Article • Annals of Neurology, October 2020, Wiley

    Professor Fredrik Piehl

  75. Infections in patients with multiple sclerosis: A national cohort study in Sweden

    Article • Multiple Sclerosis and Related Disorders, October 2020, Elsevier

    Professor Fredrik Piehl, scott montgomery

  76. A comparative study of tolerability and effects on immunoglobulin levels and CD19 cell counts with ocrelizumab vs low dose of rituximab in multiple sclerosis

    Article • Multiple Sclerosis Journal - Experimental Translational and Clinical, October 2020, SAGE Publications

    Professor Fredrik Piehl

  77. Is the treatment of myasthenia gravis improving?

    Article • Neurology, September 2020, Wolters Kluwer Health

    Professor Fredrik Piehl

  78. The DQB1*03:02 Genotype and Treatment for Pain in People With and Without Multiple Sclerosis

    Article • Frontiers in Neurology, September 2020, Frontiers

    scott montgomery, Professor Fredrik Piehl

  79. Neurological manifestations of coronavirus infections – a systematic review

    Article • Annals of Clinical and Translational Neurology, August 2020, Wiley

    Professor Fredrik Piehl

  80. Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas-Casp8-Bid-axis

    Article • Nature Communications, August 2020, Springer Science + Business Media

    Professor Fredrik Piehl

  81. The genetic architecture of human brainstem structures and their involvement in common brain disorders

    Article • Nature Communications, August 2020, Springer Science + Business Media

    Professor Fredrik Piehl

  82. Comparison Between Rituximab Treatment for New-Onset Generalized Myasthenia Gravis and Refractory Generalized Myasthenia Gravis

    Article • JAMA Neurology, August 2020, American Medical Association (AMA)

    Professor Fredrik Piehl

  83. Non-infectious comorbidity in patients with multiple sclerosis: A national cohort study in Sweden

    Article • Multiple Sclerosis Journal - Experimental Translational and Clinical, July 2020, SAGE Publications

    scott montgomery, Professor Fredrik Piehl

  84. Characterization of More Selective Central Nervous System Nrf2-Activating Novel Vinyl Sulfoximine Compounds Compared to Dimethyl Fumarate

    Article • Neurotherapeutics, July 2020, Elsevier

    Professor Fredrik Piehl, Elias Arner

  85. Diagnostic accuracy of intrathecal kappa free light chains compared with OCBs in MS

    Article • Neurology Neuroimmunology & Neuroinflammation, July 2020, Wolters Kluwer Health

    Professor Fredrik Piehl

  86. Rituximab, MS, and pregnancy

    Article • Neurology Neuroimmunology & Neuroinflammation, July 2020, Wolters Kluwer Health

    Professor Fredrik Piehl

  87. Enlarged perivascular spaces in multiple sclerosis on magnetic resonance imaging: a systematic review and meta-analysis

    Article • Deutsche Zeitschrift für Nervenheilkunde, June 2020, Springer Science + Business Media

    Professor Fredrik Piehl

  88. Plasma neurofilament light levels are associated with risk of disability in multiple sclerosis

    Article • Neurology, June 2020, Wolters Kluwer Health

    Professor Fredrik Piehl

  89. CSF levels of synaptosomal-associated protein 25 and synaptotagmin-1 in first-episode psychosis subjects

    Article • IBRO Reports, June 2020, Elsevier

    Professor Fredrik Piehl

  90. Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas/Casp8/Bid-axis

    Article • May 2020, Cold Spring Harbor Laboratory Press

    Professor Fredrik Piehl

  91. Inflammation-related plasma and CSF biomarkers for multiple sclerosis

    Article • Proceedings of the National Academy of Sciences, May 2020, Proceedings of the National Academy of Sciences

    Ingrid Kockum, Professor Fredrik Piehl

  92. Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study

    Article • The Lancet Neurology, April 2020, Elsevier

    Professor Fredrik Piehl

  93. Cancer Risk for Fingolimod, Natalizumab, and Rituximab in Multiple Sclerosis Patients

    Article • Annals of Neurology, March 2020, Wiley

    Professor Fredrik Piehl

  94. Validation of Rapid Magnetic Resonance Myelin Imaging in Multiple Sclerosis

    Article • Annals of Neurology, March 2020, Wiley

    Professor Fredrik Piehl

  95. A Novel, Robust Method for Quantification of Multiple Kynurenine Pathway Metabolites in the Cerebrospinal Fluid

    Article • Bioanalysis, March 2020, Taylor & Francis

    Professor Fredrik Piehl

  96. Blood neurofilament light levels segregate treatment effects in multiple sclerosis

    Article • Neurology, February 2020, Wolters Kluwer Health

    Benedicte Delcoigne, Professor Fredrik Piehl

  97. Infection Risks Among Patients With Multiple Sclerosis Treated With Fingolimod, Natalizumab, Rituximab, and Injectable Therapies

    Article • JAMA Neurology, February 2020, American Medical Association (AMA)

    Professor Fredrik Piehl

  98. Interrupting rituximab treatment in relapsing-remitting multiple sclerosis; no evidence of rebound disease activity

    Article • Multiple Sclerosis and Related Disorders, January 2020, Elsevier

    Professor Fredrik Piehl

  99. Confounding effect of blood volume and body mass index on blood neurofilament light chain levels

    Article • Annals of Clinical and Translational Neurology, January 2020, Wiley

    Professor Fredrik Piehl

  100. Creatinine and C-reactive protein in amyotrophic lateral sclerosis, multiple sclerosis and Parkinson’s disease

    Article • Brain Communications, January 2020, Oxford University Press (OUP)

    Professor Fredrik Piehl

  101. Quantification of Plasma Kynurenine Metabolites Following One Bout of Sprint Interval Exercise

    Article • International Journal of Tryptophan Research, January 2020, SAGE Publications

    Professor Fredrik Piehl

  102. MRI‐Based Manual versus Automated Corpus Callosum Volumetric Measurements in Multiple Sclerosis

    Article • Journal of Neuroimaging, November 2019, Wiley

    Professor Fredrik Piehl

  103. Retinal nerve fiber layer thickness associates with cognitive impairment and physical disability in multiple sclerosis

    Article • Multiple Sclerosis and Related Disorders, November 2019, Elsevier

    Professor Fredrik Piehl

  104. Successful combined treatment with thymectomy, rituximab and tocilizumab for severe thymoma-associated multi autoimmune syndrome

    Article • Journal of Neuroimmunology, November 2019, Elsevier

    Professor Fredrik Piehl

  105. A Serum Protein Biomarker Panel Improves Outcome Prediction in Human Traumatic Brain Injury

    Article • Journal of Neurotrauma, October 2019, Mary Ann Liebert Inc

    Professor Fredrik Piehl

  106. Epilepsy in systemic lupus erythematosus: prevalence and risk factors

    Article • European Journal of Neurology, October 2019, Wiley

    Professor Fredrik Piehl

  107. Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

    Article • Science, September 2019, American Association for the Advancement of Science

    Dr Jacob L McCauley, Professor Fredrik Piehl

  108. Common brain disorders are associated with heritable patterns of apparent aging of the brain

    Article • Nature Neuroscience, September 2019, Springer Science + Business Media

    Professor Fredrik Piehl

  109. Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology

    Article • JAMA Neurology, September 2019, American Medical Association (AMA)

    Professor Fredrik Piehl

  110. Different epigenetic clocks reflect distinct pathophysiological features of multiple sclerosis

    Article • Epigenomics, September 2019, Taylor & Francis

    Professor Fredrik Piehl

  111. Incidence of osmotic demyelination syndrome in Sweden: A nationwide study

    Article • Acta Neurologica Scandinavica, August 2019, Wiley

    Professor Fredrik Piehl

  112. Non-parametric combination analysis of multiple data types enables detection of novel regulatory mechanisms in T cells of multiple sclerosis patients

    Article • Scientific Reports, August 2019, Springer Science + Business Media

    Professor Fredrik Piehl

  113. Comparative effectiveness of dimethyl fumarate as the initial and secondary treatment for MS

    Article • Multiple Sclerosis Journal, August 2019, SAGE Publications

    Professor Fredrik Piehl

  114. Increased peripheral levels of TARC/CCL17 in first episode psychosis patients

    Article • Schizophrenia Research, August 2019, Elsevier

    Professor Fredrik Piehl

  115. GM-CSF and CXCR4 define a T helper cell signature in multiple sclerosis

    Article • Nature Medicine, July 2019, Springer Science + Business Media

    Felix Hartmann, Professor Fredrik Piehl

  116. Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes

    Article • Nature Communications, July 2019, Springer Science + Business Media

    Professor Fredrik Piehl

  117. Brain Heterogeneity in Schizophrenia and Its Association With Polygenic Risk

    Article • JAMA Psychiatry, July 2019, American Medical Association (AMA)

    Professor Fredrik Piehl

  118. Rituximab treatment for multiple sclerosis

    Article • Multiple Sclerosis Journal, June 2019, SAGE Publications

    Professor Fredrik Piehl

  119. Randomized phase 2 study of FcRn antagonist efgartigimod in generalized myasthenia gravis

    Article • Neurology, June 2019, Wolters Kluwer Health

    Professor Fredrik Piehl

  120. Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

    Article • Clinical Epigenetics, May 2019, Springer Science + Business Media

    Professor Fredrik Piehl

  121. Dynamics of extracellular matrix proteins in cerebrospinal fluid and serum and their relation to clinical outcome in human traumatic brain injury

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), April 2019, De Gruyter

    Professor Fredrik Piehl

  122. Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progression

    Article • EBioMedicine, April 2019, Elsevier

    Professor Fredrik Piehl

  123. The association between multiple sclerosis and pain medications: Erratum.

    Article • Pain, April 2019, Wolters Kluwer Health

    scott montgomery, Professor Fredrik Piehl

  124. Natalizumab, rituximab and fingolimod as escalation therapy in multiple sclerosis

    Article • European Journal of Neurology, March 2019, Wiley

    Professor Fredrik Piehl

  125. Validation of the Swedish Multiple Sclerosis Register

    Article • Epidemiology, March 2019, Wolters Kluwer Health

    Professor Fredrik Piehl

  126. B cell alterations during BAFF inhibition with belimumab in SLE

    Article • EBioMedicine, February 2019, Elsevier

    Professor Fredrik Piehl

  127. Morvan’s syndrome treated successfully with rituximab and lacosamide

    Article • BMJ Case Reports, February 2019, BMJ

    Professor Fredrik Piehl

  128. Author Correction: Multiple sclerosis

    Article • Nature Reviews Disease Primers, November 2018, Springer Science + Business Media

    Professor Fredrik Piehl, Dr. Alessandra Solari

  129. Multiple sclerosis

    Article • Nature Reviews Disease Primers, November 2018, Springer Science + Business Media

    Professor Fredrik Piehl, Dr. Alessandra Solari

  130. International consensus on quality standards for brain health-focused care in multiple sclerosis

    Article • Multiple Sclerosis Journal, November 2018, SAGE Publications

    Professor Tjalf Ziemssen, Professor Fredrik Piehl

  131. The association between multiple sclerosis and pain medications

    Article • Pain, October 2018, Wolters Kluwer Health

    scott montgomery, Professor Fredrik Piehl

  132. miR-31 regulates energy metabolism and is suppressed in T cells from patients with Sjögren's syndrome

    Article • European Journal of Immunology, October 2018, Wiley

    Professor Fredrik Piehl

  133. Cerebrospinal fluid levels of sphingolipids associate with disease severity in first episode psychosis patients

    Article • Schizophrenia Research, September 2018, Elsevier

    Professor Fredrik Piehl

  134. Identification of MS-specific serum miRNAs in an international multicenter study

    Article • Neurology Neuroimmunology & Neuroinflammation, September 2018, Wolters Kluwer Health

    Professor Fredrik Piehl

  135. Memory B Cells Activate Brain-Homing, Autoreactive CD4+ T Cells in Multiple Sclerosis

    Article • Cell, September 2018, Elsevier

    Professor Fredrik Piehl

  136. Neurofilaments as biomarkers in neurological disorders

    Article • Nature Reviews Neurology, August 2018, Springer Science + Business Media

    Mr axel petzold, Professor Fredrik Piehl

  137. Increased number of monocytes and plasma levels ofMCP‐1 andYKL‐40 in first‐episode psychosis

    Article • Acta Psychiatrica Scandinavica, August 2018, Wiley

    Professor Fredrik Piehl

  138. Polygenic link between blood lipids and amyotrophic lateral sclerosis

    Article • Neurobiology of Aging, July 2018, Elsevier

    Professor Fredrik Piehl

  139. DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis

    Article • Nature Communications, June 2018, Springer Science + Business Media

    Professor Fredrik Piehl

  140. Comparative Effectiveness of Rituximab and Other Initial Treatment Choices for Multiple Sclerosis

    Article • JAMA Neurology, March 2018, American Medical Association (AMA)

    Professor Fredrik Piehl

  141. Depression and fatigue in multiple sclerosis: Relation to exposure to violence and cerebrospinal fluid immunomarkers

    Article • Psychoneuroendocrinology, March 2018, Elsevier

    Professor Fredrik Piehl

  142. Susceptibility to Oxidative Stress Is Determined by Genetic Background in Neuronal Cell Cultures

    Article • eNeuro, March 2018, Society for Neuroscience

    Professor Fredrik Piehl

  143. Rituximab is an acceptable alternative to ocrelizumab for treating multiple sclerosis – Yes

    Article • Multiple Sclerosis Journal, February 2018, SAGE Publications

    Professor Fredrik Piehl

  144. The changing multiple sclerosis treatment landscape: impact of new drugs and treatment recommendations

    Article • European Journal of Clinical Pharmacology, February 2018, Springer Science + Business Media

    Professor Fredrik Piehl

  145. Impact of genetic risk loci for multiple sclerosis on expression of proximal genes in patients

    Article • Human Molecular Genetics, January 2018, Oxford University Press (OUP)

    Professor Fredrik Piehl

  146. The Temporal Retinal Nerve Fiber Layer Thickness Is the Most Important Optical Coherence Tomography Estimate in Multiple Sclerosis

    Article • Frontiers in Neurology, December 2017, Frontiers

    Professor Fredrik Piehl

  147. Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study

    Article • The Lancet Neurology, December 2017, Elsevier

    Prof Corrado Angelini, Professor Fredrik Piehl

  148. Monitoring disease activity in multiple sclerosis using serum neurofilament light protein

    Article • Neurology, November 2017, Wolters Kluwer Health

    Professor Fredrik Piehl

  149. Persistence with dimethyl fumarate in relapsing-remitting multiple sclerosis: a population-based cohort study

    Article • European Journal of Clinical Pharmacology, November 2017, Springer Science + Business Media

    Professor Fredrik Piehl

  150. Successful combined targeting of B- and plasma cells in treatment refractory anti-NMDAR encephalitis

    Article • Journal of Neuroimmunology, November 2017, Elsevier

    Professor Fredrik Piehl

  151. Novel genetic loci associated HLA-B*08:01 positive myasthenia gravis

    Article • Journal of Autoimmunity, October 2017, Elsevier

    Professor Fredrik Piehl

  152. Neurodegenerative and psychiatric diseases among families with amyotrophic lateral sclerosis

    Article • Neurology, August 2017, Wolters Kluwer Health

    Professor Fredrik Piehl

  153. Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes

    Article • Multiple Sclerosis Journal, August 2017, SAGE Publications

    Professor Fredrik Piehl

  154. Rituximab in multiple sclerosis: Frequency and clinical relevance of anti-drug antibodies

    Article • Multiple Sclerosis Journal, August 2017, SAGE Publications

    Professor Fredrik Piehl

  155. A minimal unified model of disease trajectories captures hallmarks of multiple sclerosis

    Article • Mathematical Biosciences, July 2017, Elsevier

    Professor Fredrik Piehl

  156. Comparative effectiveness of rituximab relative to IFN-β or glatiramer acetate in relapsing-remitting MS from the Swedish MS registry

    Article • Multiple Sclerosis Journal, June 2017, SAGE Publications

    Professor Fredrik Piehl

  157. Plasma neurofilament light chain levels in patients with MS switching from injectable therapies to fingolimod

    Article • Multiple Sclerosis Journal, June 2017, SAGE Publications

    Professor Fredrik Piehl

  158. Beneficial effect of tocilizumab in myasthenia gravis refractory to rituximab

    Article • Neuromuscular Disorders, June 2017, Elsevier

    Professor Fredrik Piehl

  159. Cerebrospinal fluid mtDNA concentration is elevated in multiple sclerosis disease and responds to treatment

    Article • Multiple Sclerosis Journal, March 2017, SAGE Publications

    Professor Fredrik Piehl

  160. CSF GABA is reduced in first-episode psychosis and associates to symptom severity

    Article • Molecular Psychiatry, March 2017, Springer Science + Business Media

    Professor Fredrik Piehl

  161. Multiple Sclerosis—A Tuning Fork Still Required

    Article • JAMA Neurology, March 2017, American Medical Association (AMA)

    Professor Fredrik Piehl

  162. Population-based incidence and clinical characteristics of idiopathic intracranial hypertension

    Article • Acta Neurologica Scandinavica, February 2017, Hindawi Publishing Corporation

    Professor Fredrik Piehl

  163. Cross Talk in HEK293 Cells Between Nrf2, HIF, and NF-κB Activities upon Challenges with Redox Therapeutics Characterized with Single-Cell Resolution

    Article • Antioxidants & Redox Signaling, February 2017, Mary Ann Liebert Inc

    Elias Arner, Professor Fredrik Piehl

  164. Successful autologous haematopoietic stem cell transplantation for refractory myasthenia gravis – a case report

    Article • Neuromuscular Disorders, January 2017, Elsevier

    Professor Fredrik Piehl

  165. Effects ofC2tagenetic polymorphisms on MHC class II expression and autoimmune diseases

    Article • Immunology, December 2016, Wiley

    Rikard Holmdahl, Professor Fredrik Piehl

  166. Cerebrospinal fluid biomarkers as a measure of disease activity and treatment efficacy in relapsing‐remitting multiple sclerosis

    Article • Journal of Neurochemistry, November 2016, Wiley

    Professor Fredrik Piehl

  167. Rituximab in multiple sclerosis

    Article • Neurology, November 2016, Wolters Kluwer Health

    Professor Fredrik Piehl

  168. Cognitive function did not improve after initiation of natalizumab treatment in relapsing-remitting multiple sclerosis. A prospective one-year dual control group study

    Article • Multiple Sclerosis and Related Disorders, November 2016, Elsevier

    Professor Fredrik Piehl

  169. Tryptophan Metabolism Along the Kynurenine Pathway Downstream of Toll‐like Receptor Stimulation in Peripheral Monocytes

    Article • Scandinavian Journal of Immunology, October 2016, Wiley

    Professor Fredrik Piehl

  170. NR1H3 p.Arg415Gln Is Not Associated to Multiple Sclerosis Risk

    Article • Neuron, October 2016, Elsevier

    Dr Jacob L McCauley, Professor Fredrik Piehl

  171. Reply

    Article • Annals of Neurology, September 2016, Wiley

    Professor Fredrik Piehl

  172. Fatigue and depression in multiple sclerosis: pharmacological and non-pharmacological interventions

    Article • Acta Neurologica Scandinavica, September 2016, Wiley

    Professor Fredrik Piehl

  173. Guidelines for the use of magnetic resonance imaging in diagnosing and monitoring the treatment of multiple sclerosis: recommendations of the Swedish Multiple Sclerosis Association and the Swedish Neuroradiological Society

    Article • Acta Neurologica Scandinavica, August 2016, Hindawi Publishing Corporation

    Professor Fredrik Piehl

  174. Absence of systemic oxidative stress and increased CSF prostaglandin F 2α in progressive MS

    Article • Neurology Neuroimmunology & Neuroinflammation, August 2016, Wolters Kluwer Health

    Professor Fredrik Piehl

  175. T-cell activation and HLA-regulated response to smoking in the deep airways of patients with multiple sclerosis

    Article • Clinical Immunology, August 2016, Elsevier

    Professor Fredrik Piehl

  176. Cerebrospinal fluid biomarkers of inflammation and degeneration as measures of fingolimod efficacy in multiple sclerosis

    Article • Multiple Sclerosis Journal, July 2016, SAGE Publications

    Professor Fredrik Piehl

  177. Circulating miR-150 in CSF is a novel candidate biomarker for multiple sclerosis

    Article • Neurology Neuroimmunology & Neuroinflammation, June 2016, Wolters Kluwer Health

    Professor Fredrik Piehl

  178. Complement Receptor 2 is increased in cerebrospinal fluid of multiple sclerosis patients and regulates C3 function

    Article • Clinical Immunology, May 2016, Elsevier

    Professor Fredrik Piehl

  179. No Evidence for Disease History as a Risk Factor for Narcolepsy after A(H1N1)pdm09 Vaccination

    Article • PLOS One, April 2016, PLOS

    Professor Fredrik Piehl

  180. Rituximab versus fingolimod after natalizumab in multiple sclerosis patients

    Article • Annals of Neurology, April 2016, Wiley

    Professor Fredrik Piehl

  181. High-intensity resistance training in multiple sclerosis — An exploratory study of effects on immune markers in blood and cerebrospinal fluid, and on mood, fatigue, health-related quality of life, muscle strength, walking and cognition

    Article • Journal of the Neurological Sciences, March 2016, Elsevier

    Professor Fredrik Piehl

  182. Lipocalin-2 is increased in progressive multiple sclerosis and inhibits remyelination

    Article • Neurology Neuroimmunology & Neuroinflammation, February 2016, Wolters Kluwer Health

    Professor Fredrik Piehl

  183. Chronic inflammatory demyelinating polyradiculoneuropathy occurring after autologous haematopoietic stem cell transplantation for multiple sclerosis

    Article • Multiple Sclerosis Journal - Experimental Translational and Clinical, January 2016, SAGE Publications

    Professor Fredrik Piehl

  184. Cerebrospinal fluid kynurenines in multiple sclerosis; relation to disease course and neurocognitive symptoms

    Article • Brain Behavior and Immunity, January 2016, Elsevier

    Professor Fredrik Piehl

  185. Rituximab in paediatric onset multiple sclerosis: a case series

    Article • Deutsche Zeitschrift für Nervenheilkunde, November 2015, Springer Science + Business Media

    Professor Fredrik Piehl

  186. Complement receptor 2 is up regulated in the spinal cord following nerve root injury and modulates the spinal cord response

    Article • Journal of Neuroinflammation, October 2015, Springer Science + Business Media

    Professor Fredrik Piehl

  187. MicroRNAs as promising novel biomarkers and potential drug targets for inflammatory neurological diseases

    Article • Journal of the Neurological Sciences, September 2015, Elsevier

    Professor Fredrik Piehl

  188. Comparative Assessment of the Prognostic Value of Biomarkers in Traumatic Brain Injury Reveals an Independent Role for Serum Levels of Neurofilament Light

    Article • PLOS One, July 2015, PLOS

    Professor Fredrik Piehl

  189. Comparative analysis of first-year fingolimod and natalizumab drug discontinuation among Swedish patients with multiple sclerosis

    Article • Multiple Sclerosis Journal, April 2015, SAGE Publications

    Professor Fredrik Piehl

  190. Is a Cancer Diagnosis Associated with Subsequent Risk of Transient Global Amnesia?

    Article • PLOS One, April 2015, PLOS

    Professor Fredrik Piehl

  191. Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis

    Article • PLOS One, April 2015, PLOS

    Professor Fredrik Piehl

  192. P300 amplitude and response speed relate to preserved cognitive function in relapsing–remitting multiple sclerosis

    Article • Clinical Neurophysiology, April 2015, Elsevier

    Professor Fredrik Piehl

  193. Serum neurofilament light chain levels are increased in patients with a clinically isolated syndrome

    Article • Journal of Neurology Neurosurgery & Psychiatry, February 2015, BMJ

    Professor Fredrik Piehl

  194. Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study

    Article • Multiple Sclerosis Journal, February 2015, SAGE Publications

    Gavin Giovannoni, prof aksel siva, Professor Fredrik Piehl

  195. Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes

    Article • Brain, February 2015, Oxford University Press (OUP)

    Professor Fredrik Piehl

  196. Risk factors for amyotrophic lateral sclerosis

    Article • Clinical Epidemiology, February 2015, Taylor & Francis

    Dr Per Roos, Professor Fredrik Piehl

  197. Genome-Wide Association Study of Late-Onset Myasthenia Gravis: Confirmation of TNFRSF11A and Identification of ZBTB10 and Three Distinct HLA Associations

    Article • Extremophiles, January 2015, Springer Science + Business Media

    Professor Fredrik Piehl

  198. Hexosylceramides as intrathecal markers of worsening disability in multiple sclerosis

    Article • Multiple Sclerosis Journal, December 2014, SAGE Publications

    Professor Fredrik Piehl

  199. The autoimmune spectrum of myasthenia gravis: a Swedish population‐based study

    Article • Journal of Internal Medicine, November 2014, Wiley

    Professor Fredrik Piehl

  200. High interleukin-6 and impulsivity: determining the role of endophenotypes in attempted suicide

    Article • Translational Psychiatry, October 2014, Springer Science + Business Media

    Professor Fredrik Piehl

  201. Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells

    Article • Nature Communications, October 2014, Springer Science + Business Media

    Professor Fredrik Piehl, Felix Hartmann

  202. High Glutathione-S-transferase 4 alpha expression promotes nerve cell survival in neurodegenerative disorders

    Article • Journal of Neuroimmunology, October 2014, Elsevier

    Professor Fredrik Piehl

  203. Genetic study of Pandemrix-associated narcolepsy

    Article • Journal of Neuroimmunology, October 2014, Elsevier

    Professor Fredrik Piehl

  204. Methylome characterization of CD4+ T cells in multiple sclerosis — Establishing a role for miR-21 in autoimmune disease

    Article • Journal of Neuroimmunology, October 2014, Elsevier

    Professor Fredrik Piehl

  205. Autologous hematopoietic stem cell transplantation in neuromyelitis optica: A registry study of the EBMT Autoimmune Diseases Working Party

    Article • Multiple Sclerosis Journal, July 2014, SAGE Publications

    Professor Fredrik Piehl

  206. Age-dependent effects on the treatment response of natalizumab in MS patients

    Article • Multiple Sclerosis Journal, May 2014, SAGE Publications

    Professor Fredrik Piehl

  207. A changing treatment landscape for multiple sclerosis: challenges and opportunities

    Article • Journal of Internal Medicine, March 2014, Wiley

    Professor Fredrik Piehl

  208. Unbiased Expression Mapping Identifies a Link between the Complement and Cholinergic Systems in the Rat Central Nervous System

    Article • The Journal of Immunology, February 2014, Oxford University Press (OUP)

    Professor Fredrik Piehl

  209. Variability in the CIITA gene interacts with HLA in multiple sclerosis

    Article • Genes & Immunity, January 2014, Springer Science + Business Media

    Senior Professor Johnny Ludvigsson, Professor Fredrik Piehl

  210. Phenotypes and Predictors of Pain Following Traumatic Spinal Cord Injury: A Prospective Study

    Article • Journal of Pain, January 2014, Elsevier

    Professor Fredrik Piehl

  211. Variability in C-Type Lectin Receptors Regulates Neuropathic Pain-Like Behavior after Peripheral Nerve Injury

    Article • Molecular Pain, January 2014, SAGE Publications

    Professor Fredrik Piehl

  212. Functional variability in butyrylcholinesterase activity regulates intrathecal cytokine and astroglial biomarker profiles in patients with Alzheimer's disease

    Article • Neurobiology of Aging, November 2013, Elsevier

    Professor Fredrik Piehl

  213. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

    Article • Nature Genetics, September 2013, Springer Science + Business Media

    Dr Jacob L McCauley, Professor Fredrik Piehl

  214. Regulated Extracellular Choline Acetyltransferase Activity— The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway

    Article • PLOS One, June 2013, PLOS

    Professor Fredrik Piehl

  215. Genetic variability in the rat Aplec C-type lectin gene cluster regulates lymphocyte trafficking and motor neuron survival after traumatic nerve root injury

    Article • Journal of Neuroinflammation, May 2013, Springer Science + Business Media

    Professor Fredrik Piehl

  216. Intense Inflammation and Nerve Damage in Early Multiple Sclerosis Subsides at Older Age: A Reflection by Cerebrospinal Fluid Biomarkers

    Article • PLOS One, May 2013, PLOS

    Professor Fredrik Piehl

  217. Correction: Systemic Inflammation in Progressive Multiple Sclerosis Involves Follicular T-Helper, Th17- and Activated B-Cells and Correlates with Progression

    Article • PLOS One, March 2013, PLOS

    Professor Fredrik Piehl

  218. Naturally Occurring Variation in the Glutathione-S-Transferase 4 Gene Determines Neurodegeneration After Traumatic Brain Injury

    Article • Antioxidants & Redox Signaling, March 2013, Mary Ann Liebert Inc

    Professor Fredrik Piehl

  219. Systemic Inflammation in Progressive Multiple Sclerosis Involves Follicular T-Helper, Th17- and Activated B-Cells and Correlates with Progression

    Article • PLOS One, March 2013, PLOS

    Professor Fredrik Piehl

  220. The DQB1*03:02 HLA haplotype is associated with increased risk of chronic pain after inguinal hernia surgery and lumbar disc herniation

    Article • Pain, March 2013, Wolters Kluwer Health

    Professor Fredrik Piehl

  221. Cognitive Impairment Has a Strong Relation to Nonsomatic Symptoms of Depression in Relapsing-Remitting Multiple Sclerosis

    Article • Archives of Clinical Neuropsychology, January 2013, Oxford University Press (OUP)

    Professor Fredrik Piehl

  222. Strain influences on inflammatory pathway activation, cell infiltration and complement cascade after traumatic brain injury in the rat

    Article • Brain Behavior and Immunity, January 2013, Elsevier

    Professor Fredrik Piehl

  223. In vivo TSPO imaging in patients with multiple sclerosis: a brain PET study with [18F]FEDAA1106

    Article • EJNMMI Research, January 2013, Springer Science + Business Media

    Professor Fredrik Piehl

  224. Multiple sclerosis risk genotypes correlate with an elevated cerebrospinal fluid level of the suggested prognostic marker CXCL13

    Article • Multiple Sclerosis Journal, November 2012, SAGE Publications

    Professor Fredrik Piehl

  225. Low vascular endothelial growth factor and interleukin-8 in cerebrospinal fluid of suicide attempters

    Article • Translational Psychiatry, November 2012, Springer Science + Business Media

    Professor Fredrik Piehl

  226. Time to secondary progression in patients with multiple sclerosis who were treated with first generation immunomodulating drugs

    Article • Multiple Sclerosis Journal, November 2012, SAGE Publications

    Professor Fredrik Piehl

  227. Age-dependent variation of genotypes in MHC II transactivator gene (CIITA) in controls and association to type 1 diabetes

    Article • Genes & Immunity, October 2012, Springer Science + Business Media

    Senior Professor Johnny Ludvigsson, Professor Fredrik Piehl

  228. Risk for myasthenia gravis maps to a 151Pro→Ala change in TNIP1 and to human leukocyte antigen‐B*08

    Article • Annals of Neurology, October 2012, Wiley

    Professor Fredrik Piehl

  229. The Calcitonin Receptor Gene Is a Candidate for Regulation of Susceptibility to Herpes simplex Type 1 Neuronal Infection Leading to Encephalitis in Rat

    Article • PLoS Pathogens, June 2012, PLOS

    Professor Fredrik Piehl

  230. Genetic and sex influence on neuropathic pain‐like behaviour after spinal cord injury in the rat

    Article • European Journal of Pain, April 2012, Wiley

    Professor Fredrik Piehl

  231. Unmet medical needs with current standard treatments

    Article • March 2012, Future Medicine

    Professor Fredrik Piehl

  232. iNOS-mediated secondary inflammatory response differs between rat strains following experimental brain contusion

    Article • Acta Neurochirurgica, February 2012, Springer Science + Business Media

    Professor Fredrik Piehl

  233. Naturally Occurring Genetic Variability in Expression of Gsta4 is Associated with Differential Survival of Axotomized Rat Motoneurons

    Article • NeuroMolecular Medicine, December 2011, Springer Science + Business Media

    Professor Fredrik Piehl

  234. Inflammatory and haemostatic markers in idiopathic intracranial hypertension

    Article • Journal of Internal Medicine, September 2011, Wiley

    Professor Fredrik Piehl

  235. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Article • Nature, August 2011, Springer Science + Business Media

    Professor Janusz Antoni Jankowski, Professor Fredrik Piehl

  236. Concomitant autoimmunity in myasthenia gravis — Lack of association with IgA deficiency

    Article • Journal of Neuroimmunology, July 2011, Elsevier

    Professor Fredrik Piehl

  237. Both MHC and non-MHC genes regulate inflammation and T-cell response after traumatic brain injury

    Article • Brain Behavior and Immunity, July 2011, Elsevier

    Professor Fredrik Piehl

  238. The Expression of VEGF-A Is Down Regulated in Peripheral Blood Mononuclear Cells of Patients with Secondary Progressive Multiple Sclerosis

    Article • PLOS One, May 2011, PLOS

    Professor Fredrik Piehl

  239. A Swedish national post-marketing surveillance study of natalizumab treatment in multiple sclerosis

    Article • Multiple Sclerosis Journal, January 2011, SAGE Publications

    Professor Fredrik Piehl

  240. High levels of 15-oxygenated steroids in circulation of patients with multiple sclerosis: fact or fiction?

    Article • Journal of Lipid Research, January 2011, Elsevier

    Professor Fredrik Piehl

  241. Profiling of CD4+ T Cells with Epigenetic Immune Lineage Analysis

    Article • The Journal of Immunology, January 2011, Oxford University Press (OUP)

    Professor Fredrik Piehl

  242. Axonal damage in relapsing multiple sclerosis is markedly reduced by natalizumab

    Article • Annals of Neurology, December 2010, Wiley

    Professor Fredrik Piehl

  243. Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course

    Article • Multiple Sclerosis Journal, December 2010, SAGE Publications

    Professor Fredrik Piehl

  244. Influence of Perineurial Cells and Toll-Like Receptors 2 and 9 on Herpes simplex Type 1 Entry to the Central Nervous System in Rat Encephalitis

    Article • PLOS One, August 2010, PLOS

    Professor Fredrik Piehl

  245. Genetic regulation of microglia activation, complement expression, and neurodegeneration in a rat model of traumatic brain injury

    Article • Experimental Brain Research, July 2010, Springer Science + Business Media

    Professor Fredrik Piehl

  246. Swedish natalizumab (Tysabri) multiple sclerosis surveillance study

    Article • Neurological Sciences, June 2010, Springer Science + Business Media

    Professor Fredrik Piehl

  247. Genetic aspects in TBI

    Article • Frontiers in Neurology, January 2010, Frontiers

    Professor Fredrik Piehl

  248. Differential nerve injury-induced expression of MHC class II in the mouse correlates to genetic variability in the type I promoter of C2ta

    Article • Journal of Neuroimmunology, July 2009, Elsevier

    Professor Fredrik Piehl

  249. Identification of gene regions regulating inflammatory microglial response in the rat CNS after nerve injury

    Article • Journal of Neuroimmunology, July 2009, Elsevier

    Professor Fredrik Piehl

  250. Fine Mapping of Gene Regions Regulating Neurodegeneration

    Article • PLOS One, June 2009, PLOS

    Professor Fredrik Piehl

  251. The effects of natalizumab on inflammatory mediators in multiple sclerosis: prospects for treatment‐sensitive biomarkers

    Article • European Journal of Neurology, March 2009, Wiley

    Professor Fredrik Piehl

  252. Inflammation and susceptibility to neurodegeneration: The use of unbiased genetics to decipher critical regulatory pathways

    Article • Neuroscience, February 2009, Elsevier

    Professor Fredrik Piehl

  253. Contrasting genetic effects of major histocompatibility complex on ischemic peripheral nerve and spinal cord injury in female rats

    Article • Neuroscience Letters, October 2008, Elsevier

    Professor Fredrik Piehl

  254. Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study

    Article • The Lancet, October 2008, Elsevier

    Professor Fredrik Piehl

  255. Both MHC and non-MHC genes regulate development of experimental neuropathic pain in rats

    Article • Neuroscience Letters, September 2008, Elsevier

    Professor Fredrik Piehl

  256. Genetic analysis of neuropathic pain-like behavior following peripheral nerve injury suggests a role of the major histocompatibility complex in development of allodynia

    Article • Pain, June 2008, Wolters Kluwer Health

    Professor Fredrik Piehl

  257. Vra4 Congenic Rats with Allelic Differences in the Class II Transactivator Gene Display Altered Susceptibility to Experimental Autoimmune Encephalomyelitis

    Article • The Journal of Immunology, March 2008, Oxford University Press (OUP)

    Professor Fredrik Piehl

  258. Host strain-dependent difference in susceptibility in a rat model of herpes simplex type 1 encephalitis

    Article • Journal of NeuroVirology, January 2008, Springer Science + Business Media

    Professor Fredrik Piehl

  259. The axon reaction: Identifying the genes that make a difference

    Article • Physiology & Behavior, September 2007, Elsevier

    Professor Fredrik Piehl

  260. Recovery from spinal cord injury differs between rat strains in a major histocompatibility complex-independent manner

    Article • European Journal of Neuroscience, August 2007, Wiley

    Professor Fredrik Piehl

  261. The incidence and significance of anti-natalizumab antibodies: Results from AFFIRM and SENTINEL

    Article • Neurology, August 2007, Wolters Kluwer Health

    Professor Michael Hutchinson, Professor Fredrik Piehl

  262. Decreased Expression of VEGF‐A in Rat Experimental Autoimmune Encephalomyelitis and in Cerebrospinal Fluid Mononuclear Cells from Patients with Multiple Sclerosis

    Article • Scandinavian Journal of Immunology, February 2007, Wiley

    Professor Fredrik Piehl

  263. Genetics of autoimmune neuroinflammation

    Article • Current Opinion in Immunology, December 2006, Elsevier

    Professor Fredrik Piehl

  264. Decreased Expression of VEGF‐A in Rat Experimental Autoimmune Encephalomyelitis and in Cerebrospinal Fluid Mononuclear Cells from Patients with Multiple Sclerosis

    Article • Scandinavian Journal of Immunology, November 2006, Wiley

    Professor Fredrik Piehl

  265. Genetically determined susceptibility to neurodegeneration is associated with expression of inflammatory genes

    Article • Neurobiology of Disease, October 2006, Elsevier

    Professor Fredrik Piehl

  266. Differential Expression of the Chemokine Receptors CX3CR1 and CCR1 by Microglia and Macrophages in Myelin-Oligodendrocyte-Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis

    Article • Brain Pathology, April 2006, Wiley

    Professor Fredrik Piehl

  267. Genetic Regulation of Nerve Avulsion-Induced Spinal Cord Inflammation

    Article • Annals of the New York Academy of Sciences, January 2006, Wiley

    Professor Fredrik Piehl

  268. Inflammation and neurodegeneration

    Article • Future Neurology, January 2006, Future Medicine

    Professor Fredrik Piehl

  269. Expression of T cell immunoglobulin- and mucin-domain-containing molecules-1 and -3 (TIM-1 and -3) in the rat nervous and immune systems

    Article • Journal of Neuroimmunology, July 2005, Elsevier

    Professor Fredrik Piehl

  270. Genetic dissection of neurodegeneration and CNS inflammation

    Article • Journal of the Neurological Sciences, June 2005, Elsevier

    Professor Fredrik Piehl

  271. MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction

    Article • Nature Genetics, April 2005, Springer Science + Business Media

    Professor Fredrik Piehl

  272. A role for MHC class I molecules in synaptic plasticity and regeneration of neurons after axotomy

    Article • Proceedings of the National Academy of Sciences, December 2004, Proceedings of the National Academy of Sciences

    Professor Fredrik Piehl

  273. T Cell Ig- and Mucin-Domain-Containing Molecule-3 (TIM-3) and TIM-1 Molecules Are Differentially Expressed on Human Th1 and Th2 Cells and in Cerebrospinal Fluid-Derived Mononuclear Cells in Multiple Sclerosis

    Article • The Journal of Immunology, June 2004, Oxford University Press (OUP)

    Professor Fredrik Piehl

  274. Prior poliomyelitis—IvIg treatment reduces proinflammatory cytokine production

    Article • Journal of Neuroimmunology, May 2004, Elsevier

    Professor Fredrik Piehl

  275. Increased Brain‐Derived Neurotrophic Factor Expression in White Blood Cells of Relapsing–Remitting Multiple Sclerosis Patients

    Article • Scandinavian Journal of Immunology, May 2003, Wiley

    Professor Fredrik Piehl

  276. Harm or heal – divergent effects of autoimmune neuroinflammation?

    Article • Trends in Immunology, January 2003, Elsevier

    Professor Fredrik Piehl

  277. Properties of motoneurons underlying their regenerative capacity after axon lesions in the ventral funiculus or at the surface of the spinal cord

    Article • Brain Research Reviews, October 2002, Elsevier

    Professor Fredrik Piehl

  278. Facial nerve lesion response; strain differences but no involvement of IFN-γ, STAT4 or STAT6

    Article • Neuroreport, September 2002, Wolters Kluwer Health

    Professor Fredrik Piehl

  279. Upregulation of VEGF-A Without Angiogenesis in a Mouse Model of Dilated Cardiomyopathy Caused by Mitochondrial Dysfunction

    Article • Journal of Histochemistry & Cytochemistry, July 2002, SAGE Publications

    Professor Fredrik Piehl

  280. Differential Expression of Neurotrophic Factors and Inflammatory Cytokines by Myelin Basic Protein‐Specific and Other Recruited T Cells Infiltrating the Central Nervous System during Experimental Autoimmune Encephalomyelitis

    Article • Scandinavian Journal of Immunology, March 2002, Wiley

    Professor Fredrik Piehl

  281. Differential expression of multiple alternative spliceforms of the Men1 tumor suppressor gene in mouse

    Article • International Journal of Molecular Medicine, December 2001, Spandidos Publications

    Professor Fredrik Piehl

  282. Neuroinflammation in the rat - CNS cells and their role in the regulation of immune reactions

    Article • Immunological Reviews, December 2001, Wiley

    Professor Fredrik Piehl

  283. Menin Interacts Directly with the Homeobox-Containing Protein Pem

    Article • Biochemical and Biophysical Research Communications, August 2001, Elsevier

    Professor Fredrik Piehl

  284. Neurodegeneration and glial activation patterns after mechanical nerve injury are differentially regulated by non‐MHC genes in congenic inbred rat strains

    Article • The Journal of Comparative Neurology, February 2001, Wiley

    Professor Fredrik Piehl

  285. Neurodegeneration and glial activation patterns after mechanical nerve injury are differentially regulated by non-MHC genes in congenic inbred rat strains

    Article • The Journal of Comparative Neurology, January 2001, Wiley

    Professor Fredrik Piehl

  286. Induction of VEGF and VEGF receptors in the spinal cord after mechanical spinal injury and prostaglandin administration

    Article • European Journal of Neuroscience, October 2000, Wiley

    Professor Fredrik Piehl

  287. Neuroprotection by Encephalomyelitis: Rescue of Mechanically Injured Neurons and Neurotrophin Production by CNS-Infiltrating T and Natural Killer Cells

    Article • Journal of Neuroscience, July 2000, Society for Neuroscience

    Professor Fredrik Piehl

  288. Genetics of rat neuroinflammation

    Article • Journal of Neuroimmunology, July 2000, Elsevier

    Professor Robert Weissert, Professor Fredrik Piehl

  289. Molecular characterization of human and murine C11orf5, a new member of the FAUNA gene cluster

    Article • Mammalian Genome, January 2000, Springer Science + Business Media

    Professor Fredrik Piehl

  290. Differential regulation of trophic factor receptor mRNAs in spinal motoneurons after sciatic nerve transection and ventral root avulsion in the rat

    Article • The Journal of Comparative Neurology, January 2000, Wiley

    Professor Fredrik Piehl

  291. Reduction of both pro- and anti-inflammatory cytokines after 6 months of interferon beta-1a treatment of multiple sclerosis

    Article • Journal of Neuroimmunology, January 2000, Elsevier

    Professor Fredrik Piehl

  292. Regulation of laminin-associated integrin subunit mRNAs in rat spinal motoneurons during postnatal development and after axonal injury

    Article • The Journal of Comparative Neurology, January 2000, Wiley

    Professor Fredrik Piehl

  293. Expression of nonclassical MHC class I (RT1-U) in certain neuronal populations of the central nervous system

    Article • European Journal of Neuroscience, December 1999, Wiley

    Professor Fredrik Piehl

  294. Expression of MHC class I heavy chain and β2-microglobulin in rat brainstem motoneurons and nigral dopaminergic neurons

    Article • Journal of Neuroimmunology, November 1999, Elsevier

    Professor Fredrik Piehl

  295. Non-MHC gene regulation of nerve root injury induced spinal cord inflammation and neuron death

    Article • Journal of Neuroimmunology, November 1999, Elsevier

    Professor Fredrik Piehl

  296. Restricted Expression Pattern ofvegf-din the Adult and Fetal Mouse: High Expression in the Embryonic Lung

    Article • Biochemical and Biophysical Research Communications, April 1999, Elsevier

    Professor Fredrik Piehl

  297. Expression of insulin-like growth factors and corresponding binding proteins (IGFBP 1-6) in rat spinal cord and peripheral nerve after axonal injuries

    Article • The Journal of Comparative Neurology, October 1998, Wiley

    Professor Fredrik Piehl

  298. Expression of insulin‐like growth factors and corresponding binding proteins (IGFBP 1–6) in rat spinal cord and peripheral nerve after axonal injuries

    Article • The Journal of Comparative Neurology, October 1998, Wiley

    Professor Fredrik Piehl

  299. Characterization of the mouse Men1 gene and its expression during development

    Article • Oncogene, October 1998, Springer Science + Business Media

    Professor Fredrik Piehl

  300. Characterization of the human synaptogyrin gene family

    Article • Human Genetics, September 1998, Springer Science + Business Media

    Professor Fredrik Piehl

  301. Expression and chromosomal localization of the Requiem gene

    Article • Mammalian Genome, August 1998, Springer Science + Business Media

    Professor Fredrik Piehl

  302. Expression of theBCL6Gene in the Pre- and Postnatal Mouse

    Article • Biochemical and Biophysical Research Communications, June 1998, Elsevier

    Professor Fredrik Piehl

  303. A comparative study of the expression patterns for vegf, vegf-b/vrf and vegf-c in the developing and adult mouse

    Article • Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, June 1998, Elsevier

    Professor Fredrik Piehl

  304. Mapping of the human Ca2+ channel β4 subunit to 2q22-23 and its expression in developing mouse

    Article • Mammalian Genome, April 1998, Springer Science + Business Media

    Professor Fredrik Piehl

  305. Changes in the mRNA expression pattern, with special reference to calcitonin gene-related peptide, after axonal injuries in rat motoneurons depends on age and type of injury

    Article • Experimental Brain Research, February 1998, Springer Science + Business Media

    Professor Fredrik Piehl

  306. VAMP‐1 and VAMP‐2 gene expression in rat spinal motoneurones: differential regulation after neuronal injury

    Article • European Journal of Neuroscience, January 1998, Wiley

    Professor Fredrik Piehl

  307. Article • Journal of Neuroscience Research, January 1998, Wiley

    Professor Fredrik Piehl

  308. Expression of LAZ3/BCL6 in follicular center (FC) B cells of reactive lymph nodes and FC-derived non-Hodgkin lymphomas

    Article • Leukemia, April 1997, Springer Science + Business Media

    Professor Fredrik Piehl

  309. Sequence and Expression of the Mouse Homologue to Human Phospholipase C β3 Neighboring Gene

    Article • Biochemical and Biophysical Research Communications, June 1996, Elsevier

    Professor Fredrik Piehl

  310. Differential subcellular localization of SNAP-25a and SNAP-25b RNA transcripts in spinal motoneurons and plasticity in expression after nerve injury

    Article • Molecular Brain Research, April 1996, Elsevier

    Professor Fredrik Piehl

  311. Expression of the VEGF-Related Factor Gene in Pre- and Postnatal Mouse

    Article • Biochemical and Biophysical Research Communications, March 1996, Elsevier

    Professor Fredrik Piehl

  312. GDNF mRNA in Schwann cells and DRG satellite cells after chronic sciatic nerve injury

    Article • Neuroreport, March 1996, Wolters Kluwer Health

    Professor Fredrik Piehl

  313. Expression of the phosphoinositide-specific phospholipase Cβ3 gene in the rat

    Article • Neuroreport, December 1995, Wolters Kluwer Health

    Professor Fredrik Piehl

  314. Differential effects of combined trk receptor mutations on dorsal root ganglion and inner ear sensory neurons

    Article • Development, December 1995, The Company of Biologists

    Professor Fredrik Piehl

  315. Prominent Expression of bFGF in Dorsal Root Ganglia after Axotomy

    Article • European Journal of Neuroscience, December 1995, Wiley

    Professor Fredrik Piehl

  316. Expression of NMDA Receptor mRNAs in Rat Motoneurons is Down-regulated after Axotomy

    Article • European Journal of Neuroscience, October 1995, Wiley

    Professor Fredrik Piehl

  317. Increase in α-CGRP and GAP-43 in aged motoneurons: A study of peptides, growth factors, and ChAT mRNA in the lumbar spinal cord of senescent rats with symptoms of hindlimb incapacities

    Article • The Journal of Comparative Neurology, August 1995, Wiley

    Professor Fredrik Piehl

  318. Fibroblast Growth Factors Regulate Calcitonin Gene-related Peptide mRNA Expression in Rat Motoneurons after Lesion and in Culture

    Article • European Journal of Neuroscience, August 1995, Wiley

    Professor Fredrik Piehl

  319. Adhesive/Repulsive Properties in the Injured Spinal Cord: Relation to Myelin Phagocytosis by Invading Macrophages

    Article • Experimental Neurology, October 1994, Elsevier

    Professor Fredrik Piehl

  320. Increased trkB mRNA expression by axotomized motoneurones

    Article • Neuroreport, February 1994, Wolters Kluwer Health

    Professor Fredrik Piehl

  321. trkC-like Immunoreactivity in the Primate Descending Serotoninergic System

    Article • European Journal of Neuroscience, February 1994, Wiley

    Professor Fredrik Piehl

  322. The peptidergic motoneurone

    Article • Neuroreport, July 1993, Wolters Kluwer Health

    Professor Fredrik Piehl

  323. Calcitonin Gene-Related Peptide in the Brain, Spinal Cord, and Some Peripheral Systems

    Article • Annals of the New York Academy of Sciences, June 1992, Wiley

    Professor Fredrik Piehl

  324. Calcitonin Gene-related Peptide (CGRP)-like Immunoreactivity and CGRP mRNA in Rat Spinal Cord Motoneurons after Different Types of Lesions

    Article • European Journal of Neuroscience, August 1991, Wiley

    Professor Fredrik Piehl