All Stories

  1. Cerebrospinal fluid brevican and neurocan fragment patterns in human traumatic brain injury

    Article • Clinica Chimica Acta, January 2021, Elsevier

    Professor Fredrik Piehl

  2. Current and emerging disease modulatory therapies and treatment targets for multiple sclerosis

    Article • Journal of Internal Medicine, December 2020, Wiley

    Professor Fredrik Piehl

  3. Absence of Neuronal Autoantibodies in Neuropsychiatric Systemic Lupus Erythematosus

    Article • Annals of Neurology, October 2020, Wiley

    Professor Fredrik Piehl

  4. Infections in patients with multiple sclerosis: A national cohort study in Sweden

    Article • Multiple Sclerosis and Related Disorders, October 2020, Elsevier

    Professor Fredrik Piehl

  5. Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas-Casp8-Bid-axis

    Article • Nature Communications, August 2020, Springer Science + Business Media

    Professor Fredrik Piehl

  6. Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas/Casp8/Bid-axis

    Article • May 2020, Cold Spring Harbor Laboratory Press

    Professor Fredrik Piehl

  7. Interrupting rituximab treatment in relapsing-remitting multiple sclerosis; no evidence of rebound disease activity

    Article • Multiple Sclerosis and Related Disorders, January 2020, Elsevier

    Professor Fredrik Piehl

  8. Retinal nerve fiber layer thickness associates with cognitive impairment and physical disability in multiple sclerosis

    Article • Multiple Sclerosis and Related Disorders, November 2019, Elsevier

    Professor Fredrik Piehl

  9. Rituximab treatment for multiple sclerosis

    Article • Multiple Sclerosis Journal, June 2019, SAGE Publications

    Professor Fredrik Piehl

  10. Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progression

    Article • EBioMedicine, April 2019, Elsevier

    Professor Fredrik Piehl

  11. Rituximab is an acceptable alternative to ocrelizumab for treating multiple sclerosis – Yes

    Article • Multiple Sclerosis Journal, February 2018, SAGE Publications

    Professor Fredrik Piehl

  12. Novel genetic loci associated HLA-B*08:01 positive myasthenia gravis

    Article • Journal of Autoimmunity, October 2017, Elsevier

    Professor Fredrik Piehl

  13. Plasma neurofilament light chain levels in patients with MS switching from injectable therapies to fingolimod

    Article • Multiple Sclerosis Journal, June 2017, SAGE Publications

    Professor Fredrik Piehl

  14. MicroRNAs as promising novel biomarkers and potential drug targets for inflammatory neurological diseases

    Article • Journal of the Neurological Sciences, September 2015, Elsevier

    Professor Fredrik Piehl

  15. P300 amplitude and response speed relate to preserved cognitive function in relapsing–remitting multiple sclerosis

    Article • Clinical Neurophysiology, April 2015, Elsevier

    Professor Fredrik Piehl

  16. Risk factors for amyotrophic lateral sclerosis

    Article • Clinical Epidemiology, February 2015, Taylor & Francis

    Dr Per Roos, Professor Fredrik Piehl

  17. Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells

    Article • Nature Communications, October 2014, Springer Science + Business Media

    Professor Fredrik Piehl, Felix Hartmann

  18. High Glutathione-S-transferase 4 alpha expression promotes nerve cell survival in neurodegenerative disorders

    Article • Journal of Neuroimmunology, October 2014, Elsevier

    Professor Fredrik Piehl

  19. Genetic study of Pandemrix-associated narcolepsy

    Article • Journal of Neuroimmunology, October 2014, Elsevier

    Professor Fredrik Piehl

  20. Methylome characterization of CD4+ T cells in multiple sclerosis — Establishing a role for miR-21 in autoimmune disease

    Article • Journal of Neuroimmunology, October 2014, Elsevier

    Professor Fredrik Piehl

  21. Phenotypes and Predictors of Pain Following Traumatic Spinal Cord Injury: A Prospective Study

    Article • Journal of Pain, January 2014, Elsevier

    Professor Fredrik Piehl

  22. Variability in C-Type Lectin Receptors Regulates Neuropathic Pain-Like Behavior after Peripheral Nerve Injury

    Article • Molecular Pain, January 2014, SAGE Publications

    Professor Fredrik Piehl

  23. Regulated Extracellular Choline Acetyltransferase Activity— The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway

    Article • PLoS ONE, June 2013, PLOS

    Professor Fredrik Piehl

  24. Genetic variability in the rat Aplec C-type lectin gene cluster regulates lymphocyte trafficking and motor neuron survival after traumatic nerve root injury

    Article • Journal of Neuroinflammation, May 2013, Springer Science + Business Media

    Professor Fredrik Piehl

  25. Intense Inflammation and Nerve Damage in Early Multiple Sclerosis Subsides at Older Age: A Reflection by Cerebrospinal Fluid Biomarkers

    Article • PLoS ONE, May 2013, PLOS

    Professor Fredrik Piehl

  26. Correction: Systemic Inflammation in Progressive Multiple Sclerosis Involves Follicular T-Helper, Th17- and Activated B-Cells and Correlates with Progression

    Article • PLoS ONE, March 2013, PLOS

    Professor Fredrik Piehl

  27. Naturally Occurring Variation in the Glutathione-S-Transferase 4 Gene Determines Neurodegeneration After Traumatic Brain Injury

    Article • Antioxidants & Redox Signaling, March 2013, Mary Ann Liebert Inc

    Professor Fredrik Piehl

  28. Systemic Inflammation in Progressive Multiple Sclerosis Involves Follicular T-Helper, Th17- and Activated B-Cells and Correlates with Progression

    Article • PLoS ONE, March 2013, PLOS

    Professor Fredrik Piehl

  29. The DQB1*03:02 HLA haplotype is associated with increased risk of chronic pain after inguinal hernia surgery and lumbar disc herniation

    Article • Pain, March 2013, Wolters Kluwer Health

    Professor Fredrik Piehl

  30. Strain influences on inflammatory pathway activation, cell infiltration and complement cascade after traumatic brain injury in the rat

    Article • Brain Behavior and Immunity, January 2013, Elsevier

    Professor Fredrik Piehl

  31. In vivo TSPO imaging in patients with multiple sclerosis: a brain PET study with [18F]FEDAA1106

    Article • EJNMMI Research, January 2013, Springer Science + Business Media

    Professor Fredrik Piehl

  32. The Calcitonin Receptor Gene Is a Candidate for Regulation of Susceptibility to Herpes simplex Type 1 Neuronal Infection Leading to Encephalitis in Rat

    Article • PLoS Pathogens, June 2012, PLOS

    Professor Fredrik Piehl

  33. Unmet medical needs with current standard treatments

    Article • March 2012, Future Medicine

    Professor Fredrik Piehl

  34. iNOS-mediated secondary inflammatory response differs between rat strains following experimental brain contusion

    Article • Acta Neurochirurgica, February 2012, Springer Science + Business Media

    Professor Fredrik Piehl

  35. Naturally Occurring Genetic Variability in Expression of Gsta4 is Associated with Differential Survival of Axotomized Rat Motoneurons

    Article • NeuroMolecular Medicine, December 2011, Springer Science + Business Media

    Professor Fredrik Piehl

  36. Concomitant autoimmunity in myasthenia gravis — Lack of association with IgA deficiency

    Article • Journal of Neuroimmunology, July 2011, Elsevier

    Professor Fredrik Piehl

  37. Both MHC and non-MHC genes regulate inflammation and T-cell response after traumatic brain injury

    Article • Brain Behavior and Immunity, July 2011, Elsevier

    Professor Fredrik Piehl

  38. The Expression of VEGF-A Is Down Regulated in Peripheral Blood Mononuclear Cells of Patients with Secondary Progressive Multiple Sclerosis

    Article • PLoS ONE, May 2011, PLOS

    Professor Fredrik Piehl

  39. Axonal damage in relapsing multiple sclerosis is markedly reduced by natalizumab

    Article • Annals of Neurology, December 2010, Wiley

    Professor Fredrik Piehl

  40. Influence of Perineurial Cells and Toll-Like Receptors 2 and 9 on Herpes simplex Type 1 Entry to the Central Nervous System in Rat Encephalitis

    Article • PLoS ONE, August 2010, PLOS

    Professor Fredrik Piehl

  41. Genetic regulation of microglia activation, complement expression, and neurodegeneration in a rat model of traumatic brain injury

    Article • Experimental Brain Research, July 2010, Springer Science + Business Media

    Professor Fredrik Piehl

  42. Swedish natalizumab (Tysabri) multiple sclerosis surveillance study

    Article • Neurological Sciences, June 2010, Springer Science + Business Media

    Professor Fredrik Piehl

  43. Genetic aspects in TBI

    Article • Frontiers in Neurology, January 2010, Frontiers

    Professor Fredrik Piehl

  44. Differential nerve injury-induced expression of MHC class II in the mouse correlates to genetic variability in the type I promoter of C2ta

    Article • Journal of Neuroimmunology, July 2009, Elsevier

    Professor Fredrik Piehl

  45. Identification of gene regions regulating inflammatory microglial response in the rat CNS after nerve injury

    Article • Journal of Neuroimmunology, July 2009, Elsevier

    Professor Fredrik Piehl

  46. Fine Mapping of Gene Regions Regulating Neurodegeneration

    Article • PLoS ONE, June 2009, PLOS

    Professor Fredrik Piehl

  47. Both MHC and non-MHC genes regulate development of experimental neuropathic pain in rats

    Article • Neuroscience Letters, September 2008, Elsevier

    Professor Fredrik Piehl

  48. Genetic analysis of neuropathic pain-like behavior following peripheral nerve injury suggests a role of the major histocompatibility complex in development of allodynia

    Article • Pain, June 2008, Wolters Kluwer Health

    Professor Fredrik Piehl

  49. Host strain-dependent difference in susceptibility in a rat model of herpes simplex type 1 encephalitis

    Article • Journal of NeuroVirology, January 2008, Springer Science + Business Media

    Professor Fredrik Piehl

  50. The axon reaction: Identifying the genes that make a difference

    Article • Physiology & Behavior, September 2007, Elsevier

    Professor Fredrik Piehl

  51. Recovery from spinal cord injury differs between rat strains in a major histocompatibility complex-independent manner

    Article • European Journal of Neuroscience, August 2007, Wiley

    Professor Fredrik Piehl

  52. Genetics of autoimmune neuroinflammation

    Article • Current Opinion in Immunology, December 2006, Elsevier

    Professor Fredrik Piehl

  53. Genetically determined susceptibility to neurodegeneration is associated with expression of inflammatory genes

    Article • Neurobiology of Disease, October 2006, Elsevier

    Professor Fredrik Piehl

  54. Differential Expression of the Chemokine Receptors CX3CR1 and CCR1 by Microglia and Macrophages in Myelin-Oligodendrocyte-Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis

    Article • Brain Pathology, April 2006, Wiley

    Professor Fredrik Piehl

  55. Genetic Regulation of Nerve Avulsion-Induced Spinal Cord Inflammation

    Article • Annals of the New York Academy of Sciences, January 2006, Wiley

    Professor Fredrik Piehl

  56. Inflammation and neurodegeneration

    Article • Future Neurology, January 2006, Future Medicine

    Professor Fredrik Piehl

  57. Expression of T cell immunoglobulin- and mucin-domain-containing molecules-1 and -3 (TIM-1 and -3) in the rat nervous and immune systems

    Article • Journal of Neuroimmunology, July 2005, Elsevier

    Professor Fredrik Piehl

  58. Genetic dissection of neurodegeneration and CNS inflammation

    Article • Journal of the Neurological Sciences, June 2005, Elsevier

    Professor Fredrik Piehl

  59. MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction

    Article • Nature Genetics, April 2005, Springer Science + Business Media

    Professor Fredrik Piehl

  60. Prior poliomyelitis—IvIg treatment reduces proinflammatory cytokine production

    Article • Journal of Neuroimmunology, May 2004, Elsevier

    Professor Fredrik Piehl

  61. Facial nerve lesion response; strain differences but no involvement of IFN-γ, STAT4 or STAT6

    Article • Neuroreport, September 2002, Wolters Kluwer Health

    Professor Fredrik Piehl

  62. Differential expression of multiple alternative spliceforms of the Men1 tumor suppressor gene in mouse

    Article • International Journal of Molecular Medicine, December 2001, Spandidos Publications

    Professor Fredrik Piehl

  63. Neuroinflammation in the rat - CNS cells and their role in the regulation of immune reactions

    Article • Immunological Reviews, December 2001, Wiley

    Professor Fredrik Piehl

  64. Menin Interacts Directly with the Homeobox-Containing Protein Pem

    Article • Biochemical and Biophysical Research Communications, August 2001, Elsevier

    Professor Fredrik Piehl

  65. Neurodegeneration and glial activation patterns after mechanical nerve injury are differentially regulated by non‐MHC genes in congenic inbred rat strains

    Article • The Journal of Comparative Neurology, February 2001, Wiley

    Professor Fredrik Piehl

  66. Neurodegeneration and glial activation patterns after mechanical nerve injury are differentially regulated by non-MHC genes in congenic inbred rat strains

    Article • The Journal of Comparative Neurology, January 2001, Wiley

    Professor Fredrik Piehl

  67. Induction of VEGF and VEGF receptors in the spinal cord after mechanical spinal injury and prostaglandin administration

    Article • European Journal of Neuroscience, October 2000, Wiley

    Professor Fredrik Piehl

  68. Molecular characterization of human and murine C11orf5, a new member of the FAUNA gene cluster

    Article • Mammalian Genome, January 2000, Springer Science + Business Media

    Professor Fredrik Piehl

  69. Differential regulation of trophic factor receptor mRNAs in spinal motoneurons after sciatic nerve transection and ventral root avulsion in the rat

    Article • The Journal of Comparative Neurology, January 2000, Wiley

    Professor Fredrik Piehl

  70. Reduction of both pro- and anti-inflammatory cytokines after 6 months of interferon beta-1a treatment of multiple sclerosis

    Article • Journal of Neuroimmunology, January 2000, Elsevier

    Professor Fredrik Piehl

  71. Regulation of laminin-associated integrin subunit mRNAs in rat spinal motoneurons during postnatal development and after axonal injury

    Article • The Journal of Comparative Neurology, January 2000, Wiley

    Professor Fredrik Piehl

  72. Expression of nonclassical MHC class I (RT1-U) in certain neuronal populations of the central nervous system

    Article • European Journal of Neuroscience, December 1999, Wiley

    Professor Fredrik Piehl

  73. Expression of MHC class I heavy chain and β2-microglobulin in rat brainstem motoneurons and nigral dopaminergic neurons

    Article • Journal of Neuroimmunology, November 1999, Elsevier

    Professor Fredrik Piehl

  74. Non-MHC gene regulation of nerve root injury induced spinal cord inflammation and neuron death

    Article • Journal of Neuroimmunology, November 1999, Elsevier

    Professor Fredrik Piehl

  75. Restricted Expression Pattern ofvegf-din the Adult and Fetal Mouse: High Expression in the Embryonic Lung

    Article • Biochemical and Biophysical Research Communications, April 1999, Elsevier

    Professor Fredrik Piehl

  76. Expression of insulin-like growth factors and corresponding binding proteins (IGFBP 1-6) in rat spinal cord and peripheral nerve after axonal injuries

    Article • The Journal of Comparative Neurology, October 1998, Wiley

    Professor Fredrik Piehl

  77. Expression of insulin‐like growth factors and corresponding binding proteins (IGFBP 1–6) in rat spinal cord and peripheral nerve after axonal injuries

    Article • The Journal of Comparative Neurology, October 1998, Wiley

    Professor Fredrik Piehl

  78. Characterization of the mouse Men1 gene and its expression during development

    Article • Oncogene, October 1998, Springer Science + Business Media

    Professor Fredrik Piehl

  79. Characterization of the human synaptogyrin gene family

    Article • Human Genetics, September 1998, Springer Science + Business Media

    Professor Fredrik Piehl

  80. Expression and chromosomal localization of the Requiem gene

    Article • Mammalian Genome, August 1998, Springer Science + Business Media

    Professor Fredrik Piehl

  81. Expression of theBCL6Gene in the Pre- and Postnatal Mouse

    Article • Biochemical and Biophysical Research Communications, June 1998, Elsevier

    Professor Fredrik Piehl

  82. A comparative study of the expression patterns for vegf, vegf-b/vrf and vegf-c in the developing and adult mouse

    Article • Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, June 1998, Elsevier

    Professor Fredrik Piehl

  83. Mapping of the human Ca2+ channel β4 subunit to 2q22-23 and its expression in developing mouse

    Article • Mammalian Genome, April 1998, Springer Science + Business Media

    Professor Fredrik Piehl

  84. VAMP‐1 and VAMP‐2 gene expression in rat spinal motoneurones: differential regulation after neuronal injury

    Article • European Journal of Neuroscience, January 1998, Wiley

    Professor Fredrik Piehl

  85. Sequence and Expression of the Mouse Homologue to Human Phospholipase C β3 Neighboring Gene

    Article • Biochemical and Biophysical Research Communications, June 1996, Elsevier

    Professor Fredrik Piehl

  86. Differential subcellular localization of SNAP-25a and SNAP-25b RNA transcripts in spinal motoneurons and plasticity in expression after nerve injury

    Article • Molecular Brain Research, April 1996, Elsevier

    Professor Fredrik Piehl

  87. Expression of the VEGF-Related Factor Gene in Pre- and Postnatal Mouse

    Article • Biochemical and Biophysical Research Communications, March 1996, Elsevier

    Professor Fredrik Piehl

  88. Expression of the phosphoinositide-specific phospholipase Cβ3 gene in the rat

    Article • Neuroreport, December 1995, Wolters Kluwer Health

    Professor Fredrik Piehl

  89. Expression of NMDA Receptor mRNAs in Rat Motoneurons is Down-regulated after Axotomy

    Article • European Journal of Neuroscience, October 1995, Wiley

    Professor Fredrik Piehl

  90. Increase in α-CGRP and GAP-43 in aged motoneurons: A study of peptides, growth factors, and ChAT mRNA in the lumbar spinal cord of senescent rats with symptoms of hindlimb incapacities

    Article • The Journal of Comparative Neurology, August 1995, Wiley

    Professor Fredrik Piehl

  91. Fibroblast Growth Factors Regulate Calcitonin Gene-related Peptide mRNA Expression in Rat Motoneurons after Lesion and in Culture

    Article • European Journal of Neuroscience, August 1995, Wiley

    Professor Fredrik Piehl

  92. Adhesive/Repulsive Properties in the Injured Spinal Cord: Relation to Myelin Phagocytosis by Invading Macrophages

    Article • Experimental Neurology, October 1994, Elsevier

    Professor Fredrik Piehl

  93. Increased trkB mRNA expression by axotomized motoneurones

    Article • Neuroreport, February 1994, Wolters Kluwer Health

    Professor Fredrik Piehl

  94. trkC-like Immunoreactivity in the Primate Descending Serotoninergic System

    Article • European Journal of Neuroscience, February 1994, Wiley

    Professor Fredrik Piehl

  95. The peptidergic motoneurone

    Article • Neuroreport, July 1993, Wolters Kluwer Health

    Professor Fredrik Piehl

  96. Calcitonin Gene-Related Peptide in the Brain, Spinal Cord, and Some Peripheral Systems

    Article • Annals of the New York Academy of Sciences, June 1992, Wiley

    Professor Fredrik Piehl

  97. Calcitonin Gene-related Peptide (CGRP)-like Immunoreactivity and CGRP mRNA in Rat Spinal Cord Motoneurons after Different Types of Lesions

    Article • European Journal of Neuroscience, August 1991, Wiley

    Professor Fredrik Piehl