All Stories

  1. LIPID MAPS: Powering discovery in lipidomics

    Article • Science Signaling, May 2026, American Association for the Advancement of Science

    Dr. Xueli Guan

  2. Endogenous formation of phosphatidylhomoserine in Escherichia coli through phosphatidylserine synthase

    Article • Journal of Biological Chemistry, July 2025, Elsevier

    Dr. Xueli Guan

  3. The Health for Life in Singapore (HELIOS) Study: delivering Precision Medicine research for Asian populations

    Article • May 2024, Cold Spring Harbor Laboratory Press

    Dr. Xueli Guan

  4. microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data

    Article • Nature Microbiology, February 2024, Springer Science + Business Media

    Dr Andrew Patterson, Dr. Xueli Guan

  5. Assessing variations in manual pipetting: An under-investigated requirement of good laboratory practice

    Article • Journal of Mass Spectrometry and Advances in the Clinical Lab, November 2023, Elsevier

    Dr. Xueli Guan

  6. Angiopoietin-like 4 shapes the intrahepatic T-cell landscape via eIF2α signaling during steatohepatitis in diet-induced NAFLD

    Article • January 2023, Cold Spring Harbor Laboratory Press

    Dr. Xueli Guan

  7. LipidA-IDER to Explore the Global Lipid A Repertoire of Drug-Resistant Gram-Negative Bacteria

    Article • Analytical Chemistry, January 2023, American Chemical Society (ACS)

    Dr. Xueli Guan

  8. Draft Genome Sequence of Enterobacter hormaechei subsp. steigerwaltii Strain BEI01

    Article • Microbiology Resource Announcements, July 2021, ASM Journals

    Dr. Xueli Guan

  9. Biosynthetic intermediates of the enterobacterial common antigen overcome outer membrane lipid dyshomeostasis in Escherichia coli

    Article • November 2018, Cold Spring Harbor Laboratory Press

    Dr. Xueli Guan

  10. Macrophage–Bacteria Interactions—A Lipid-Centric Relationship

    Article • Frontiers in Immunology, December 2017, Frontiers

    Dr. Xueli Guan

  11. Comparative sphingolipidomics of disease-causing trypanosomatids reveal unique lifecycle- and taxonomy-specific lipid chemistries

    Article • Scientific Reports, October 2017, Springer Science + Business Media

    Dr. Xueli Guan

  12. Lipid metabolism in mycobacteria—Insights using mass spectrometry-based lipidomics

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, January 2016, Elsevier

    Dr. Xueli Guan

  13. The fusogenic lipid phosphatidic acid promotes the biogenesis of mitochondrial outer membrane protein Ugo1

    Article • Journal of Cell Biology, September 2015, Rockefeller University Press

    Dr. Xueli Guan

  14. Co-option of Membrane Wounding Enables Virus Penetration into Cells

    Article • Cell Host & Microbe, July 2015, Elsevier

    Dr. Xueli Guan

  15. Match-making for posaconazole through systems thinking

    Article • Trends in Parasitology, February 2015, Elsevier

    Dr. Xueli Guan

  16. Lipidomics and genomics of Mycobacterium tuberculosis reveal lineage‐specific trends in mycolic acid biosynthesis

    Article • MicrobiologyOpen, September 2014, Wiley

    Dr Damien Portevin, Dr. Xueli Guan

  17. Gill tissue lipids of salmon (Salmo salar L.) presmolts and smolts from anadromous and landlocked populations

    Article • Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology, June 2014, Elsevier

    Dr. Xueli Guan

  18. Lipidomics identifies a requirement for peroxisomal function during influenza virus replication

    Article • Journal of Lipid Research, May 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Xueli Guan

  19. A computational framework for integration of lipidomics data into metabolic pathways

    Article • Metabolic Engineering, May 2014, Elsevier

    Professor Vassily Hatzimanikatis, Dr. Xueli Guan

  20. Genome profiling of sterol synthesis shows convergent evolution in parasites and guides chemotherapeutic attack

    Article • Journal of Lipid Research, March 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Xueli Guan

  21. Biochemical Membrane Lipidomics during Drosophila Development

    Article • Developmental Cell, January 2013, Elsevier

    Prof. Gisou van der Goot, Dr. Xueli Guan

  22. The Stem Region of Premembrane Protein Plays an Important Role in the Virus Surface Protein Rearrangement during Dengue Maturation

    Article • Journal of Biological Chemistry, October 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Xueli Guan

  23. Targeted and Non-Targeted Analysis of Membrane Lipids Using Mass Spectrometry

    Article • January 2012, Elsevier

    Dr. Xueli Guan

  24. A Systems Biology Approach Reveals the Role of a Novel Methyltransferase in Response to Chemical Stress and Lipid Homeostasis

    Article • PLoS Genetics, October 2011, PLOS

    Professor Corey Nislow, Dr. Xueli Guan

  25. A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistance

    Article • Metabolic Engineering, September 2011, Elsevier

    Dr. Xueli Guan

  26. Phosphatidic Acid Is a pH Biosensor That Links Membrane Biogenesis to Metabolism

    Article • Science, August 2010, American Association for the Advancement of Science

    Dr. Xueli Guan

  27. Characterization of Substrate Preference for Slc1p and Cst26p in Saccharomyces cerevisiae Using Lipidomic Approaches and an LPAAT Activity Assay

    Article • PLOS One, August 2010, PLOS

    Dr. Xueli Guan

  28. Toward one step analysis of cellular lipidomes using liquid chromatography coupled with mass spectrometry: application to Saccharomyces cerevisiae and Schizosaccharomyces pombe lipidomics

    Article • Molecular BioSystems, January 2010, Royal Society of Chemistry

    Dr. Xueli Guan

  29. Yeast Lipid Analysis and Quantification by Mass Spectrometry

    Article • January 2010, Elsevier

    Dr. Xueli Guan

  30. Mitochondrial Cardiolipin Involved in Outer-Membrane Protein Biogenesis: Implications for Barth Syndrome

    Article • Current Biology, December 2009, Elsevier

    Dr. Xueli Guan

  31. A combined proteomic and genetic analysis identifies a role for the lipid desaturase Desat1 in starvation-induced autophagy in Drosophila

    Article • Autophagy, October 2009, Taylor & Francis

    Dr. Xueli Guan

  32. Functional Interactions between Sphingolipids and Sterols in Biological Membranes Regulating Cell Physiology

    Article • Molecular Biology of the Cell, April 2009, American Society for Cell Biology (ASCB)

    Dr. Xueli Guan

  33. The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis

    Article • Journal of Cell Biology, December 2008, Rockefeller University Press

    Dr. Xueli Guan

  34. Trans-Golgi Network and Endosome Dynamics Connect Ceramide Homeostasis with Regulation of the Unfolded Protein Response and TOR Signaling in Yeast

    Article • Molecular Biology of the Cell, November 2008, American Society for Cell Biology (ASCB)

    Dr. Xueli Guan

  35. Biochemistry of inositol lipids

    Article • Frontiers in Bioscience, January 2008, IMR Press

    Dr. Xueli Guan

  36. Expression, activity, and role of serine palmitoyltransferase in the rat hippocampus after kainate injury

    Article • Journal of Neuroscience Research, February 2007, Wiley

    Dr. Xueli Guan

  37. Non-targeted profiling of lipids during kainate-induced neuronal injury

    Article • The FASEB Journal, June 2006, Federation of American Societies For Experimental Biology (FASEB)

    Dr. Xueli Guan

  38. Mass spectrometry-based profiling of phospholipids and sphingolipids in extracts fromSaccharomyces cerevisiae

    Article • Yeast, January 2006, Wiley

    Dr. Xueli Guan

  39. Compensatory caspase activation in MPP+-induced cell death in dopaminergic neurons

    Article • Cellular and Molecular Life Sciences, January 2005, Springer Science + Business Media

    Dr. Xueli Guan