All Stories

  1. Correction: Ou-Yang, F. et al. Antiproliferation for Breast Cancer Cells by Ethyl Acetate Extract of Nepenthes thorellii x (ventricosa x maxima). Int. J. Mol. Sci. 2019, 20, 3238
  2. Application of Bioactive Compounds and Drugs to Target Epigenetic Enzymes and Non-coding RNAs, Exploiting New Delivery Systems for Cancer Therapy
  3. Correction: Zheng, L., et al. PBN11-8, a Cytotoxic Polypeptide Purified from Marine Bacillus, Suppresses Invasion and Migration of Human Hepatocellular Carcinoma Cells by Targeting Focal Adhesion Kinase Pathways. Polymers 2018, 10, 1043
  4. Cucurbitacin mediated regulation of deregulated oncogenic signaling cascades and non-coding RNAs in different cancers: Spotlight on JAK/STAT, Wnt/β-catenin, mTOR, TRAIL-mediated pathways
  5. Regulatory effects of noncoding RNAs on the interplay of oxidative stress and autophagy in cancer malignancy and therapy
  6. Luteolin mediated targeting of protein network and microRNAs in different cancers: Focus on JAK-STAT, NOTCH, mTOR and TRAIL-mediated signaling pathways
  7. Mesenchymal Stem Cells Combined With IFNγ Induce Apoptosis of Breast Cancer Cells Partially Through TRAIL
  8. Vitamin C as an Anticancer Agent: Regulation of Signaling Pathways
  9. The Prowess of Andrographolide as a Natural Weapon in the War against Cancer
  10. Methanol Extract of Usnea barbata Induces Cell Killing, Apoptosis, and DNA Damage against Oral Cancer Cells through Oxidative Stress
  11. MALAT1 as a Versatile Regulator of Cancer: Overview of the updates from Predatory role as Competitive Endogenous RNA to Mechanistic In-sights
  12. Epigenetic deregulation in cancer: Enzyme players and non-coding RNAs
  13. Targeting epigenetics in cancer: therapeutic potential of flavonoids
  14. Recent updates on true potential of an anesthetic agent as a regulator of cell signaling pathways and non-coding RNAs in different cancers: Focusing on the brighter side of propofol
  15. EGCG Mediated Targeting of Deregulated Signaling Pathways and Non-Coding RNAs in Different Cancers: Focus on JAK/STAT, Wnt/β-Catenin, TGF/SMAD, NOTCH, SHH/GLI, and TRAIL Mediated Signaling Pathways
  16. Toxic-Metal-Induced Alteration in miRNA Expression Profile as a Proposed Mechanism for Disease Development
  17. Pomegranate extract inhibits migration and invasion of oral cancer cells by downregulating matrix metalloproteinase‐2/9 and epithelial‐mesenchymal transition
  18. Editorial
  19. Interplay between epigenetic abnormalities and deregulated expression of microRNAs in cancer
  20. MicroRNA regulation of TRAIL mediated signaling in different cancers: Control of micro steering wheels during the journey from bench-top to the bedside
  21. Overview of the oncogenic signaling pathways in colorectal cancer: Mechanistic insights
  22. Manoalide Preferentially Provides Antiproliferation of Oral Cancer Cells by Oxidative Stress-Mediated Apoptosis and DNA Damage
  23. MicroRNA-143 as a new weapon against cancer: overview of the mechanistic insights and long non-coding RNA mediated regulation of miRNA-143 in different cancers
  24. Antiproliferation for Breast Cancer Cells by Ethyl Acetate Extract of Nepenthes thorellii x (ventricosa x maxima)
  25. Ethyl acetate extract of Nepenthes adrianii x clipeata induces antiproliferation, apoptosis, and DNA damage against oral cancer cells through oxidative stress
  26. Natural Product Mediated Regulation of Death Receptors and Intracellular Machinery: Fresh from the Pipeline about TRAIL-Mediated Signaling and Natural TRAIL Sensitizers
  27. Regulation of Cell Signaling Pathways by Berberine in Different Cancers: Searching for Missing Pieces of an Incomplete Jig-Saw Puzzle for an Effective Cancer Therapy
  28. Zinc-Doped Copper Oxide Nanocomposites Inhibit the Growth of Pancreatic Cancer by Inducing Autophagy Through AMPK/mTOR Pathway
  29. Regulation of Kisspeptin mediated signaling by non-coding RNAs in different cancers: the beginning of a new era
  30. Regulation of signaling pathways by β‐elemene in cancer progression and metastasis
  31. Nanoparticle systems for cancer vaccine
  32. Targeting Hedgehog signaling pathway: Paving the road for cancer therapy
  33. Garcinol Sensitizes NSCLC Cells to Standard Therapies by Regulating EMT-Modulating miRNAs
  34. Gaze through the clinical lens: molecular and clinical advancements of botanicals
  35. NEDD4 Family of E3 Ubiquitin Ligases in Breast Cancer: Spotlight on SMURFs, WWPs and NEDD4
  36. Role of Autophagy in Breast Cancer Development and Progression: Opposite Sides of the Same Coin
  37. Role of mTORC1 and mTORC2 in Breast Cancer: Therapeutic Targeting of mTOR and Its Partners to Overcome Metastasis and Drug Resistance
  38. TRAIL Mediated Signaling in Breast Cancer: Awakening Guardian Angel to Induce Apoptosis and Overcome Drug Resistance
  39. Targeting of JAK-STAT Signaling in Breast Cancer: Therapeutic Strategies to Overcome Drug Resistance
  40. Interplay of long non-coding RNAs and TGF/SMAD signaling in different cancers
  41. Effect of trail C1595T variant and gene expression on the pathogenesis of non-small cell lung cancer
  42. Integrative analysis of mRNA and microRNA expression profiles in laryngeal squamous cell carcinoma
  43. Granulin A Synergizes with Cisplatin to Inhibit the Growth of Human Hepatocellular Carcinoma
  44. Apigenin as an effective anticancer natural product: Spotlight on TRAIL, WNT/β‐catenin, JAK‐STAT pathways, and microRNAs
  45. PBN11-8, a Cytotoxic Polypeptide Purified from Marine Bacillus, Suppresses Invasion and Migration of Human Hepatocellular Carcinoma Cells by Targeting Focal Adhesion Kinase Pathways
  46. Quercetin-mediated regulation of signal transduction cascades and microRNAs: Natural weapon against cancer
  47. Bitter gourd (Momordica charantia) as a rich source of bioactive components to combat cancer naturally: Are we on the right track to fully unlock its potential as inhibitor of deregulated signaling pathways
  48. Regulation of cancer cell signaling pathways by mushrooms and their bioactive molecules: Overview of the journey from benchtop to clinical trials
  49. Piperlongumine as anticancer agent: The story so far about killing many birds with one stone
  50. MiRNAs and their interplay with PI3K/AKT/mTOR pathway in ovarian cancer cells: a potential role in platinum resistance
  51. Role of microRNA‐410 in molecular oncology: A double edged sword
  52. Emerging themes of regulation of oncogenic proteins by Solanum nigrum and its bioactive molecules in different cancers
  53. Maslinic acid as an effective anticancer agent
  54. CS5931, a novel marine polypeptide, inhibits migration and invasion of cancer cells via interacting with enolase 1
  55. MicroRNA Regulation of Telomerase Reverse Transcriptase (TERT): Micro Machines Pull Strings of Papier-Mâché Puppets
  56. MicroRNA-15a expression measured in urine samples as a potential biomarker of renal cell carcinoma
  57. Curcumin on the “flying carpets” to modulate different signal transduction cascades in cancers: Next‐generation approach to bridge translational gaps
  58. Regulation of Cell Signaling Pathways and miRNAs by Resveratrol in Different Cancers
  59. Targeting activator protein 1 signaling pathway by bioactive natural agents: Possible therapeutic strategy for cancer prevention and intervention
  60. Signaling cascades in thyroid cancer: Increasing the armory of archers to hit bullseye
  61. Potential Anticancer Properties of Osthol: A Comprehensive Mechanistic Review
  62. Exosome biogenesis, bioactivities and functions as new delivery systems of natural compounds
  63. Polymer-Based Drug Delivery Systems for Cancer
  64. Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs
  65. Expression of miR-373 and its predicted target genes E-cadherin and CD44 in patients with laryngeal squamous cell carcinoma
  66. C-Kit receptor and tryptase expressing mast cells correlate with angiogenesis in breast cancer patients
  67. Regulation of signal transduction cascades by Pterostilbenes in different cancers: Is it a death knell for oncogenic pathways
  68. Differential diagnosis of the small renal masses: role of the apparent diffusion coefficient of the diffusion-weighted MRI
  69. MicroRNA-34a: A Versatile Regulator of Myriads of Targets in Different Cancers
  70. PI3K/AKT/mTOR Pathway in Ovarian Cancer Treatment: Are We on the Right Track?
  71. Two likely targets for the anti-cancer effect of indole derivatives from cruciferous vegetables: PI3K/Akt/mTOR signalling pathway and the aryl hydrocarbon receptor
  72. Regulation of signaling pathways by tanshinones in different cancers
  73. Natural Agents-Mediated Targeting of Histone Deacetylases
  74. TRAIL, Wnt, Sonic Hedgehog, TGFβ, and miRNA Signalings Are Potential Targets for Oral Cancer Therapy
  75. Beyond circulating microRNA biomarkers: Urinary microRNAs in ovarian and breast cancer
  76. Oleuropein and Cancer Chemoprevention: The Link is Hot
  77. Journey of TRAIL from bench to bedside and its potential role in immuno-oncology
  78. Oleanolic Acid Alters Multiple Cell Signaling Pathways: Implication in Cancer Prevention and Therapy
  79. Signaling networks in TMPRSS2-ERG positive prostate cancers: Do we need a Pied Piper or sharpshooter to deal with “at large” fused oncoprotein
  80. Transferrin-Conjugated Nanocarriers as Active-Targeted Drug Delivery Platforms for Cancer Therapy
  81. effect of CTLA-4 and CD28 gene variants gastric cancer
  82. VEGF mediated signaling in oral cancer
  83. Restoring TRAIL Induced Apoptosis Using Naturopathy. Hercules Joins Hand with Nature to Triumph Over Lernaean Hydra
  84. Renal cell carcinoma: applicability of the apparent coefficient of the diffusion-weighted estimated by MRI for improving their differential diagnosis, histologic subtyping, and differentiation grade
  85. Magnetic nanomaterials and sensors for biological detection
  86. Role of nanotechnology and gene delivery systems in TRAIL based therapies
  87. Kisspeptin Mediated Signaling in Cancer
  88. Oleuropein Mediated Targeting of Signaling Network in Cancer
  89. DNA methylation, histone acetylation and methylation of epigenetic modifications as a therapeutic approach for cancers
  90. Prostate Cancer Stem Cells: Viewing Signaling Cascades at a Finer Resolution
  91. Is miR-34a a Well-equipped Swordsman to Conquer Temple of Molecular Oncology?
  92. Association between breast cancer and tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) gene 1595C/T SNP in a Pakistani population
  93. Circulating tumor cells as trigger to hematogenous spreads and potential biomarkers to predict the prognosis in ovarian cancer
  94. New Frontiers in Promoting TRAIL-Mediated Cell Death: Focus on Natural Sensitizers, miRNAs, and Nanotechnological Advancements
  95. Natural Products Mediated Regulation of Oxidative Stress and DNA Damage in Ultraviolet Exposed Skin Cells
  96. The biological complexity of RKIP signaling in human cancers
  97. Inclusion of a pH-responsive amino acid-based amphiphile in methotrexate-loaded chitosan nanoparticles as a delivery strategy in cancer therapy
  98. Anticancer drugs for the modulation of endoplasmic reticulum stress and oxidative stress
  99. Platelet-derived growth factor (PDGF) signalling in cancer: rapidly emerging signalling landscape
  100. Activation and Inhibition of ATM by Phytochemicals: Awakening and Sleeping the Guardian Angel Naturally
  101. Advances in anti-angiogenic agents for ovarian cancer treatment: The role of trebananib (AMG 386)
  102. Genetic Variants in the Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand and Death Receptor Genes Contribute to Susceptibility to Bladder Cancer
  103. Tumor Infiltrating Lymphocytes in Ovarian Cancer
  104. Citrus Fruits and their Bioactive Ingredients: Leading Four Horsemen from Front
  105. Epigenetic mechanisms in cancer: push and pull between kneaded erasers and fate writers
  106. TRAIL and Bortezomib: Killing Cancer with Two Stones
  107. Recent progress in fungus-derived bioactive agents for targeting of signaling machinery in cancer cells
  108. Association between Laryngeal Squamous Cell Carcinoma and Polymorphisms in Tumor Necrosis Factor Related Apoptosis Induce Ligand (TRAIL), TRAIL Receptor and sTRAIL Levels
  109. HIV-associated osteoporosis
  110. Overview on the complexity of androgen receptor-targeted therapy for prostate cancer
  111. Rutin mediated targeting of signaling machinery in cancer cells
  112. Methanolic Extracts of Solieria robusta Inhibits Proliferation of Oral Cancer Ca9-22 Cells via Apoptosis and Oxidative Stress
  113. Reactive Oxygen Species and Autophagy Modulation in Non-Marine Drugs and Marine Drugs
  114. Drugs from Marine Sources: Modulation of TRAIL Induced Apoptosis in Cancer Cells
  115. Antisense therapeutics in oncology: current status
  116. Anticancer Activity of Essential Oils: Targeting of Protein Networks in Cancer Cells
  117. Dealing Naturally with Stumbling Blocks on Highways and Byways of TRAIL Induced Signaling
  118. Recently Emerging Signaling Landscape of Ataxia-Telangiectasia Mutated (ATM) Kinase
  119. TRAIL Mediated Signaling in Pancreatic Cancer
  120. Hepatocellular carcinoma: targeting of oncogenic signaling networks in TRAIL resistant cancer cells
  121. Restoring TRAIL Mediated Signaling in Ovarian Cancer Cells
  122. Nanoparticle Induced Oxidative Stress in Cancer Cells: Adding New Pieces to an Incomplete Jigsaw Puzzle
  123. Ovarian Cancer: Interplay of Vitamin D Signaling and miRNA Action
  124. Hepatoprotective effect of leaves of aqueous ethanol extract of Cestrum nocturnum against paracetamol-induced hepatotoxicity
  125. Anthocyanins: Targeting of Signaling Networks in Cancer Cells
  126. Ionizing Radiations Induce Apoptosis in TRAIL Resistant Cancer Cells: in vivo and in vitro Analysis
  127. miR-421, miR-155 and miR-650: Emerging Trends of Regulation of Cancer and Apoptosis
  128. Superparamagnetic maghemite loaded poly (?- caprolactone) nanocapsules : characterization and synthesis optimization
  129. Androgen receptor and gene network: Micromechanics reassemble the signaling machinery of TMPRSS2-ERG positive prostate cancer cells
  130. Mir-34: A New Weapon Against Cancer?
  131. Physiology to the Pleiotropic Role of RNAs: Prospecting Novel Therapies
  132. TRAIL and microRNAs in the treatment of prostate cancer: therapeutic potential and role of nanotechnology
  133. miRNA and TMPRSS2-ERG do not mind their own business in prostate cancer cells
  134. BCR-ABL1 in leukemia: Disguise master outplays riding shotgun
  135. Breakpoint cluster region-c-abl oncogene 1, non-receptor tyrosine kinase signaling: Current patterns of the versatile regulator revisited
  136. Nip the HPV encoded evil in the cancer bud: HPV reshapes TRAILs and signaling landscapes
  137. While at Rome miRNA and TRAIL Do Whatever BCR-ABL Commands to Do
  138. Breast Cancer Proteome Takes More Than Two to Tango on TRAIL: Beat Them at Their Own Game
  139. Prostate cancer is known by the companionship with ATM and miRNA it keeps: craftsmen of translation have dual behaviour with tailors of life thread
  140. Prostate Cancer and Immunoproteome: Awakening and Reprogramming the Guardian Angels
  141. Algae extracts and methyl jasmonate anti-cancer activities in prostate cancer: choreographers of ‘the dance macabre’
  142. TRAIL and vitamins: opting for keys to castle of cancer proteome instead of open sesame
  143. Upon the tightrope in prostate cancer: two acrobats on the same tightrope to cross the finishline
  144. NutriTRAILomics in prostate cancer: time to have two strings to one’s bow
  145. Wnt and SHH in prostate cancer: trouble mongers occupy the TRAIL towards apoptosis
  146. TRPM channels: same ballpark, different players, and different rules in immunogenetics
  147. SMURF and NEDD4: Sharp Shooters Monitor the Gate Keepers and Ion Traffic Controllers of Lead Astray Cell
  148. PDGF: the nuts and bolts of signalling toolbox
  149. TRAIL and guardian angel of genome integrity: ATM boards TRAIL blazer
  150. ATM protein kinase: the linchpin of cellular defenses to stress
  151. One Size Fits All in Prostate Cancer: A Story Tale Whose Time has Come and Gone
  152. Getting Personal with Prostate Cancer: Adding New Pieces to an Incomplete Jigsaw Puzzle